Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1

Drug Metabolism and Pharmacokinetics

Volumn 26, Issue 2, 2011, Pages 171-179

  Shirasaka, Yoshiyuki ^a   Suzuki, Kensuke ^a   Shichiri, Megumi ^a   Nakanishi, Takeo ^a   Tamai, Ikumi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

HMG CoA reductase inhibitors; Intestinal absorption; MDR1; Mdr1a; Naringin; OATP1A2; Oatp1a5; Oatp2b1; OATP2B1; Pitavastatin

Indexed keywords

AURANTIIN; ELACRIDAR; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 1A; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 1A2; ORGANIC ANION TRANSPORTER 1A5; ORGANIC ANION TRANSPORTER 2B1; PITAVASTATIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TRANSPORT; IC 50; INTESTINE ABSORPTION; INTESTINE MUCOSA PERMEABILITY; MALE; NONHUMAN; OOCYTE; RAT; XENOPUS LAEVIS;

EID: 79955740281     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.DMPK-10-RG-073     Document Type: Article

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