Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation

Journal of Pharmacology and Experimental Therapeutics

Volumn 304, Issue 1, 2003, Pages 223-228

  Tirona, Rommel G ^a   Leake, Brenda F ^a   Wolkoff, Allan W ^b   Kim, Richard B ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ORGANIC ANION TRANSPORTER; PREGNANE X RECEPTOR; RIFAMPICIN;

ALLELE; ARTICLE; BINDING AFFINITY; CELL LEVEL; CONTROLLED STUDY; DRUG UPTAKE; ENZYME INDUCTION; EUROPE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; LIVER CELL; NEGRO; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REPORTER GENE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIBIOTICS, ANTITUBERCULAR; CARRIER PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; DNA, COMPLEMENTARY; ESTRADIOL; GENES, REPORTER; HEPATOCYTES; HUMANS; KINETICS; MEMBRANE TRANSPORT PROTEINS; ORGANIC ANION TRANSPORT POLYPEPTIDE C; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; ORGANIC CATION TRANSPORTER 1; PLASMIDS; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RIFAMPIN; SYMPORTERS; TRANS-ACTIVATION (GENETICS); TRANSFECTION;

EID: 0037216648     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.043026     Document Type: Article

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