Intestinal absorption of HMG-CoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide

Pharmaceutical Research

Volumn 27, Issue 10, 2010, Pages 2141-2149

  Shirasaka, Yoshiyuki ^a   Suzuki, Kensuke ^a   Nakanishi, Takeo ^a   Tamai, Ikumi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

intestinal absorption; Mdr1; naringin; Oatp; pravastatin

Indexed keywords

AURANTIIN; BREAST CANCER RESISTANCE PROTEIN; ELACRIDAR; MULTIDRUG RESISTANCE PROTEIN 1; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 1A2; ORGANIC ANION TRANSPORTER 1A5; ORGANIC ANION TRANSPORTER 2B1; PRAVASTATIN; RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG UPTAKE; IC 50; IN VIVO STUDY; INTESTINE ABSORPTION; INTESTINE MUCOSA PERMEABILITY; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; XENOPUS LAEVIS;

ANIMALS; BIOLOGICAL TRANSPORT; CHROMATOGRAPHY, LIQUID; FLAVANONES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; ILEUM; INTESTINAL ABSORPTION; MALE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; OOCYTES; ORGANIC ANION TRANSPORTERS; PRAVASTATIN; RATS; RATS, WISTAR; TANDEM MASS SPECTROMETRY; XENOPUS LAEVIS;

EID: 77957337144     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0216-5     Document Type: Article

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