-
1
-
-
0018369605
-
Expression in Escherichia coli of chemically synthesized genes for human insulin
-
Goeddel DV, Kleid DG, Bolivar F et al. Expression in Escherichia coli of chemically synthesized genes for human insulin. Proc. Natl Acad. Sci. USA 76(1), 106-110 (1979
-
(1979)
Proc. Natl Acad. Sci. USA
, vol.76
, Issue.1
, pp. 106-110
-
-
Goeddel, D.V.1
Kleid, D.G.2
Bolivar, F.3
-
2
-
-
54049101216
-
Drug discovery: Past, present and future
-
Malik NN. Drug discovery: past, present and future. Drug Discov. Today. 13(21-22), 909-912 (2008
-
(2008)
Drug Discov. Today
, vol.13
, Issue.21-22
, pp. 909-912
-
-
Malik, N.N.1
-
3
-
-
84857459290
-
-
Pharmaceutical Research Manufacturers Association Pharmaceutical Research And Manufacturers Association Washington DC, USA
-
Pharmaceutical Research and Manufacturers Association. Biotechnology Medicines in Development. Pharmaceutical Research and Manufacturers Association, Washington, DC, USA (2011
-
(2011)
Biotechnology Medicines in Development
-
-
-
4
-
-
84877667086
-
Protein structure, purification and characterisation
-
Wilson K, Walker J (Eds Cambridge, University Press, Cambridge, UK
-
Walker J. Protein structure, purification and characterisation. In: Practical Biochemistry Principals and Techniques. Wilson K, Walker J (Eds). Cambridge University Press, Cambridge, UK (2000
-
(2000)
Practical Biochemistry Principals and Techniques
-
-
Walker, J.1
-
6
-
-
84871394690
-
The future of peptide-based drugs
-
Craik DJ, Fairlie DP, Liras S, Price D. The future of peptide-based drugs. Chem. Biol. Drug Des. 81(1), 136-147 (2013
-
(2013)
Chem. Biol. Drug des
, vol.81
, Issue.1
, pp. 136-147
-
-
Craik, D.J.1
Fairlie, D.P.2
Liras, S.3
Price, D.4
-
7
-
-
84871380139
-
Prospects in the total synthesis of protein therapeutics
-
Chalker JM. Prospects in the total synthesis of protein therapeutics. Chem. Biol. Drug Des. 81(1), 122-135 (2013
-
(2013)
Chem. Biol. Drug des
, vol.81
, Issue.1
, pp. 122-135
-
-
Chalker, J.M.1
-
8
-
-
79955632991
-
Longer action means better drug: Tuning up protein therapeutics
-
Szlachcic A, Zakrzewska M, Otlewski J. Longer action means better drug: tuning up protein therapeutics. Biotechnol. Adv. 29(4), 436-441 (2011
-
(2011)
Biotechnol. Adv
, vol.29
, Issue.4
, pp. 436-441
-
-
Szlachcic, A.1
Zakrzewska, M.2
Otlewski, J.3
-
10
-
-
77953171768
-
Stability of protein pharmaceuticals: An update
-
Manning MC, Chou DK, Murphy BM, Payne RW, Katayama DS. Stability of protein pharmaceuticals: an update. Pharm. Res. 27(4), 544-575 (2010
-
(2010)
Pharm. Res
, vol.27
, Issue.4
, pp. 544-575
-
-
Manning, M.C.1
Chou, D.K.2
Murphy, B.M.3
Payne, R.W.4
Katayama, D.S.5
-
11
-
-
52449102139
-
Past, present, and future technologies for oral delivery of therapeutic proteins
-
Singh R, Singh S, Lillard JW Jr. Past, present, and future technologies for oral delivery of therapeutic proteins. J. Pharm. Sci. 97 (7), 2497-2523 (2008
-
(2008)
J. Pharm. Sci
, vol.97
, Issue.7
, pp. 2497-2523
-
-
Singh, R.1
Singh, S.2
Lillard Jr., J.W.3
-
12
-
-
40749145377
-
Properties and formulation of oral drug delivery systems of protein and peptides
-
Semalty A, Semalty M, Singh R, Saraf SK, Saraf S. Properties and formulation of oral drug delivery systems of protein and peptides. Indian J. Pharm. Sci. 69, 741-747 (2007
-
(2007)
Indian J. Pharm. Sci
, vol.69
, pp. 741-747
-
-
Semalty, A.1
Semalty, M.2
Singh, R.3
Saraf, S.K.4
Saraf, S.5
-
13
-
-
34548222649
-
Antimicrobial activity of truncated alpha-defensin (human neutrophil peptide (HNP)-1) analogues without disulphide bridges
-
Lundy FT, Nelson J, Lockhart D, Greer B, Harriott P, Marley JJ. Antimicrobial activity of truncated alpha-defensin (human neutrophil peptide (HNP)-1) analogues without disulphide bridges. Mol. Immunol. 45(1), 190-193 (2008
-
(2008)
Mol. Immunol
, vol.45
, Issue.1
, pp. 190-193
-
-
Lundy, F.T.1
Nelson, J.2
Lockhart, D.3
Greer, B.4
Harriott, P.5
Marley, J.J.6
-
14
-
-
77951498805
-
Protein aggregation-pathways and inf luencing factors
-
Wang W, Nema S, Teagarden D. Protein aggregation-pathways and inf luencing factors. Int. J. Pharm. 390(2), 89-99 (2010
-
(2010)
Int. J. Pharm
, vol.390
, Issue.2
, pp. 89-99
-
-
Wang, W.1
Nema, S.2
Teagarden, D.3
-
15
-
-
63749128279
-
Reducing risk, improving outcomes: Bioengineering less immunogenic protein therapeutics
-
De Groot AS, Martin W. Reducing risk, improving outcomes: bioengineering less immunogenic protein therapeutics. Clin. Immunol. 131(2), 189-201 (2009
-
(2009)
Clin. Immunol
, vol.131
, Issue.2
, pp. 189-201
-
-
De Groot, A.S.1
Martin, W.2
-
16
-
-
69249203868
-
Immunogenicity assessment of therapeutic proteins and peptides
-
Kaliyaperumal A, Jing S. Immunogenicity assessment of therapeutic proteins and peptides. Curr. Pharm. Biotechnol. 10(4), 352-358 (2009
-
(2009)
Curr. Pharm. Biotechnol
, vol.10
, Issue.4
, pp. 352-358
-
-
Kaliyaperumal, A.1
Jing, S.2
-
17
-
-
77958483948
-
Pre-clinical considerations in the assessment of immunogenicity for protein therapeutics
-
Baker M, Carr F. Pre-clinical considerations in the assessment of immunogenicity for protein therapeutics. Curr. Drug Saf. 5(4), 308-313 (2010
-
(2010)
Curr. Drug Saf
, vol.5
, Issue.4
, pp. 308-313
-
-
Baker, M.1
Carr, F.2
-
18
-
-
84868576131
-
Clinical pharmacology considerations in biologics development
-
Zhao L, Ren TH, Wang DD. Clinical pharmacology considerations in biologics development. Acta Pharmacol. Sin. 33(11), 1339-1347 (2012
-
(2012)
Acta Pharmacol. Sin
, vol.33
, Issue.11
, pp. 1339-1347
-
-
Zhao, L.1
Ren, T.H.2
Wang, D.D.3
-
19
-
-
84866735537
-
Pharmacokinetic considerations for antibody drug conjugates
-
Lin K, Tibbitts J. Pharmacokinetic considerations for antibody drug conjugates. Pharm. Res. 29(9), 2354-2366 (2012
-
(2012)
Pharm. Res
, vol.29
, Issue.9
, pp. 2354-2366
-
-
Lin, K.1
Tibbitts, J.2
-
20
-
-
18644361997
-
Pharmacokinetic and pharmacodynamic considerations in the development of therapeutic proteins
-
Mahmood I, Green M. Pharmacokinetic and pharmacodynamic considerations in the development of therapeutic proteins. Clin. Pharmacokinet. 44(4), 331-347 (2005
-
(2005)
Clin. Pharmacokinet
, vol.44
, Issue.4
, pp. 331-347
-
-
Mahmood, I.1
Green, M.2
-
21
-
-
85047692219
-
Novel formulation strategies for improving oral bioavailability of drugs with poor membrane permeation or presystemic metabolism
-
Aungst BJ. Novel formulation strategies for improving oral bioavailability of drugs with poor membrane permeation or presystemic metabolism. J. Pharm. Sci. 82(10), 979-987 (1993
-
(1993)
J. Pharm. Sci
, vol.82
, Issue.10
, pp. 979-987
-
-
Aungst, B.J.1
-
22
-
-
84871679525
-
-
Peptide Drug Discovery and Development: Translational Research in Academia and Industry Castanho M, Santos NC (Eds). Wiley-VCH, NJ, USA
-
Hamman JH, Steenekamp JH. Oral peptide drug delivery: strategies to overcome challenges. In: Peptide Drug Discovery and Development: Translational Research in Academia and Industry. Castanho M, Santos NC (Eds). Wiley-VCH, NJ, USA (2011
-
(2011)
Oral Peptide Drug Delivery: Strategies to Overcome Challenges
-
-
Hamman, J.H.1
Steenekamp, J.H.2
-
23
-
-
4344634877
-
Pharmacokinetic aspects of biotechnology products
-
Tang L, Persky AM, Hochhaus G, Meibohm B. Pharmacokinetic aspects of biotechnology products. J. Pharm. Sci. 93(9), 2184-2204 (2004
-
(2004)
J. Pharm. Sci
, vol.93
, Issue.9
, pp. 2184-2204
-
-
Tang, L.1
Persky, A.M.2
Hochhaus, G.3
Meibohm, B.4
-
24
-
-
3042616099
-
Techniques: New approaches to the delivery of biopharmaceuticals
-
Orive G, Gascon A, Hernandez R, Dominiguez-Gil A, Pedraz J. Techniques: new approaches to the delivery of biopharmaceuticals. Trends Pharmacol. Sci. 25(7), 382-387 (2004
-
(2004)
Trends Pharmacol. Sci
, vol.25
, Issue.7
, pp. 382-387
-
-
Orive, G.1
Gascon, A.2
Hernandez, R.3
Dominiguez-Gil, A.4
Pedraz, J.5
-
26
-
-
34547899919
-
Solid lipid nanoparticles as a drug delivery system for peptides and proteins
-
Almeida A, Souto E. Solid lipid nanoparticles as a drug delivery system for peptides and proteins. Adv. Drug Deliver. Rev. 59, 478-490 (2007
-
(2007)
Adv. Drug Deliver. Rev
, vol.59
, pp. 478-490
-
-
Almeida, A.1
Souto, E.2
-
27
-
-
84873643357
-
Nanoparticles as drug delivery systems
-
Wilczewska AZ, Niemirowicz K, Markiewicz KH, Car H. Nanoparticles as drug delivery systems. Pharmacol. Rep. 64(5), 1020-1037 (2012
-
(2012)
Pharmacol. Rep
, vol.64
, Issue.5
, pp. 1020-1037
-
-
Wilczewska, A.Z.1
Niemirowicz, K.2
Markiewicz, K.H.3
Car, H.4
-
28
-
-
33746872198
-
Novel delivery technologies for protein and peptide therapeutics
-
Kumar TR, Soppimath K, Nachaegari SK. Novel delivery technologies for protein and peptide therapeutics. Curr. Pharm. Biotechnol. 7(4), 261-276 (2006
-
(2006)
Curr. Pharm. Biotechnol
, vol.7
, Issue.4
, pp. 261-276
-
-
Kumar, T.R.1
Soppimath, K.2
Nachaegari, S.K.3
-
29
-
-
22244488749
-
Oral delivery of peptide drugs: Barriers and developments
-
Hamman JH, Enslin GM, Kotzé AF. Oral delivery of peptide drugs: barriers and developments. Bio. Drugs 19, 165-177 (2005
-
(2005)
Bio. Drugs
, vol.19
, pp. 165-177
-
-
Hamman, J.H.1
Enslin, G.M.2
Kotzé, A.F.3
-
30
-
-
84871436009
-
Paracellular drug absorption enhancement through tight junction modulation
-
Lemmer HJ, Hamman JH. Paracellular drug absorption enhancement through tight junction modulation. Expert Opin. Drug Deliv. 10(1), 103-114 (2013
-
(2013)
Expert Opin. Drug Deliv
, vol.10
, Issue.1
, pp. 103-114
-
-
Lemmer, H.J.1
Hamman, J.H.2
-
31
-
-
33746790243
-
Zonula occludens toxin synthetic peptide derivative AT1002 enhances in vitro and in vivo intestinal absorption of low molecular weight heparin
-
Motlekar NA, Fasano A, Wachtel MS, Youan BB. Zonula occludens toxin synthetic peptide derivative AT1002 enhances in vitro and in vivo intestinal absorption of low molecular weight heparin. J. Drug Target. 14(5), 321-329 (2006
-
(2006)
J. Drug Target
, vol.14
, Issue.5
, pp. 321-329
-
-
Motlekar, N.A.1
Fasano, A.2
Wachtel, M.S.3
Youan, B.B.4
-
32
-
-
0037027876
-
Bioadhesive polysaccharide in protein delivery system: Chitosan nanoparticles improve the intestinal absorption of insulin in vivo
-
Pan Y. Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo. Int. J. Pharm. 249, 139-147 (2002
-
(2002)
Int. J. Pharm
, vol.249
, pp. 139-147
-
-
Pan, Y.1
-
33
-
-
0033020555
-
Polymers with thiol groups: A new generation of mucoadhesive polymers?
-
Bernkop-Schnürch A, Schwarz V, Steininger S. Polymers with thiol groups: a new generation of mucoadhesive polymers? Pharm. Res. 16(6), 876-881 (1999
-
(1999)
Pharm. Res
, vol.16
, Issue.6
, pp. 876-881
-
-
Bernkop-Schnürch, A.1
Schwarz, V.2
Steininger, S.3
-
34
-
-
26644452975
-
Thiomers: A new generation of mucoadhesive polymers
-
Bernkop-Schnürch A. Thiomers: a new generation of mucoadhesive polymers. Adv. Drug Deliv. Rev. 57(11), 1569-1582 (2005
-
(2005)
Adv. Drug Deliv. Rev
, vol.57
, Issue.11
, pp. 1569-1582
-
-
Bernkop-Schnürch, A.1
-
35
-
-
0029121427
-
Penetration enhancement effect of Pz-peptide, a paracellularly transported peptide, in rabbit intestinal segments and Caco-2 cell monolayers
-
Yen WC, Lee VH. Penetration enhancement effect of Pz-peptide, a paracellularly transported peptide, in rabbit intestinal segments and Caco-2 cell monolayers. J. Control. Release 36, 25-37 (1995
-
(1995)
J. Control. Release
, vol.36
, pp. 25-37
-
-
Yen, W.C.1
Lee, V.H.2
-
36
-
-
33646492929
-
Tight junction modulation and its relationship to drug delivery
-
Salama NN, Eddington ND, Fasano A. Tight junction modulation and its relationship to drug delivery. Adv. Drug Deliv. Rev. 58, 15-28 (2006
-
(2006)
Adv. Drug Deliv. Rev
, vol.58
, pp. 15-28
-
-
Salama, N.N.1
Eddington, N.D.2
Fasano, A.3
-
37
-
-
84861995150
-
Analysis of absorption enhancers in epithelial cell models
-
Rosenthal R, Heydt MS, Amasheh M, Stein C, Fromm M, Amasheh S. Analysis of absorption enhancers in epithelial cell models. Ann. NY Acad. Sci. 1258, 86-92 (2012
-
(2012)
Ann. NY Acad. Sci
, vol.1258
, pp. 86-92
-
-
Rosenthal, R.1
Heydt, M.S.2
Amasheh, M.3
Stein, C.4
Fromm, M.5
Amasheh, S.6
-
38
-
-
75149183678
-
Glycosylation of therapeutic proteins: An effective strategy to optimize efficacy
-
Solá RJ, Griebenow K. Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy. BioDrugs 24(1), 9-21 (2010
-
(2010)
BioDrugs
, vol.24
, Issue.1
, pp. 9-21
-
-
Solá, R.J.1
Griebenow, K.2
-
39
-
-
84857582436
-
PEGylation of proteins and liposomes: A powerful and flexible strategy to improve the drug delivery
-
Milla P, Dosio F, Cattel L. PEGylation of proteins and liposomes: a powerful and flexible strategy to improve the drug delivery. Curr. Drug Metab. 13(1), 105-119 (2012
-
(2012)
Curr. Drug Metab
, vol.13
, Issue.1
, pp. 105-119
-
-
Milla, P.1
Dosio, F.2
Cattel, L.3
-
40
-
-
77954537092
-
Acyl modified chitosan derivatives for oral delivery of insulin and curcumin
-
Shelma R, Sharma CP. Acyl modified chitosan derivatives for oral delivery of insulin and curcumin. J. Mater. Sci. Mater. Med. 21(7), 2133-2140 (2010
-
(2010)
J. Mater. Sci. Mater. Med
, vol.21
, Issue.7
, pp. 2133-2140
-
-
Shelma, R.1
Sharma, C.P.2
-
41
-
-
0034617463
-
Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein
-
Fujita K, Katahira J, Horiguchi Y, Sonoda N, Furuse M, Tsukita S. Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein. FEBS Lett. 476(3), 258-261 (2000
-
(2000)
FEBS Lett
, vol.476
, Issue.3
, pp. 258-261
-
-
Fujita, K.1
Katahira, J.2
Horiguchi, Y.3
Sonoda, N.4
Furuse, M.5
Tsukita, S.6
-
42
-
-
84855935214
-
The effect of chitosan on transcellular and paracellular mechanisms in the intestinal epithelial barrier
-
Rosenthal R, Günzel D, Finger C et al. The effect of chitosan on transcellular and paracellular mechanisms in the intestinal epithelial barrier. Biomaterials 33(9), 2791-2800 (2012
-
(2012)
Biomaterials
, vol.33
, Issue.9
, pp. 2791-2800
-
-
Rosenthal, R.1
Günzel, D.2
Finger, C.3
-
43
-
-
54549097056
-
Conjugated chitosan as a novel platform for oral delivery of paclitaxel
-
Lee E, Lee J, Lee IH et al. Conjugated chitosan as a novel platform for oral delivery of paclitaxel. J. Med. Chem. 51(20), 6442-6449 (2008
-
(2008)
J. Med. Chem
, vol.51
, Issue.20
, pp. 6442-6449
-
-
Lee, E.1
Lee, J.2
Lee, I.H.3
-
44
-
-
85157101793
-
Oral drug delivery systems using chemical conjugates or physical complexes
-
doi:10.1016/j.addr.11.002 Epub ahead of print
-
Al-Hilal TA, Alam F, Byun Y. Oral drug delivery systems using chemical conjugates or physical complexes. Adv. Drug Deliv. Rev. doi:10.1016/j.addr.11. 002 (2012) (Epub ahead of print
-
(2012)
Adv. Drug Deliv. Rev
-
-
Al-Hilal, T.A.1
Alam, F.2
Byun, Y.3
-
45
-
-
79955051472
-
Diverse approaches for the enhancement of oral drug bioavailability
-
Fasinu P, Pillay V, Ndesendo VM, du Toit LC, Choonara YE. Diverse approaches for the enhancement of oral drug bioavailability. Biopharm. Drug Dispos. 32(4), 185-209 (2011
-
(2011)
Biopharm. Drug Dispos
, vol.32
, Issue.4
, pp. 185-209
-
-
Fasinu, P.1
Pillay, V.2
Ndesendo, V.M.3
Du Toit, L.C.4
Choonara, Y.E.5
-
46
-
-
81255156925
-
Oral delivery of macromolecules: Rationale underpinning Gastrointestinal Permeation Enhancement Technology (GIPET
-
Walsh EG, Adamczyk BE, Chalasani KB et al. Oral delivery of macromolecules: rationale underpinning Gastrointestinal Permeation Enhancement Technology (GIPET). Ther. Deliv. 2(12), 1595-1610 (2011
-
(2011)
Ther. Deliv
, vol.2
, Issue.12
, pp. 1595-1610
-
-
Walsh, E.G.1
Adamczyk, B.E.2
Chalasani, K.B.3
-
47
-
-
80053905149
-
Enhanced bioavailability of nano-sized chitosan-atorvastatin conjugate after oral administration to rats
-
Anwar M, Warsi MH, Mallick N et al. Enhanced bioavailability of nano-sized chitosan-atorvastatin conjugate after oral administration to rats. Eur. J. Pharm. Sci. 44(3), 241-249 (2011
-
(2011)
Eur. J. Pharm. Sci
, vol.44
, Issue.3
, pp. 241-249
-
-
Anwar, M.1
Warsi, M.H.2
Mallick, N.3
-
48
-
-
0021236615
-
An in vitro investigation of mucosa-adhesive materials for use in controlled drug delivery
-
Smart JD, Kellaway IW, Worthington HE. An in vitro investigation of mucosa-adhesive materials for use in controlled drug delivery. J. Pharm. Pharmacol. 36(5), 295-299 (1984
-
(1984)
J. Pharm. Pharmacol
, vol.36
, Issue.5
, pp. 295-299
-
-
Smart, J.D.1
Kellaway, I.W.2
Worthington, H.E.3
-
49
-
-
0000856347
-
Studies on potential bioadhesive systems for oral drug delivery
-
Harris D, Fell JT, Sharma H, Taylo DC, Linch J. Studies on potential bioadhesive systems for oral drug delivery. STP Pharmacol. 5, 852e6 (1989
-
(1989)
STP Pharmacol
, vol.5
-
-
Harris, D.1
Fell, J.T.2
Sharma, H.3
Taylo, D.C.4
Linch, J.5
-
50
-
-
83355177971
-
Preactivated thiomers as mucoadhesive polymers for drug delivery
-
Iqbal J, Shahnaz G, Dünnhaupt S, Müller C, Hintzen F, Bernkop-Schnürch A. Preactivated thiomers as mucoadhesive polymers for drug delivery. Biomaterials 33(5), 1528-1535 (2012
-
(2012)
Biomaterials
, vol.33
, Issue.5
, pp. 1528-1535
-
-
Iqbal, J.1
Shahnaz, G.2
Dünnhaupt, S.3
Müller, C.4
Hintzen, F.5
Bernkop-Schnürch, A.6
-
51
-
-
0026802436
-
The human MUC2 intestinal mucin has cysteine-rich subdomains located both upstream and downstream of its central repetitive region
-
Gum JR Jr, Hicks JW, Toribara NW, Rothe EM, Lagace RE, Kim YS. The human MUC2 intestinal mucin has cysteine-rich subdomains located both upstream and downstream of its central repetitive region. J. Biol. Chem. 267(30), 21375-21383 (1992
-
(1992)
J. Biol. Chem
, vol.267
, Issue.30
, pp. 21375-21383
-
-
Gum Jr., J.R.1
Hicks, J.W.2
Toribara, N.W.3
Rothe, E.M.4
Lagace, R.E.5
Kim, Y.S.6
-
52
-
-
3843126497
-
Thiomers: Potential excipients for non-invasive peptide delivery systems
-
Bernkop-Schnürch A, Krauland AH, Leitner VM, Palmberger T. Thiomers: potential excipients for non-invasive peptide delivery systems. Eur. J. Pharm. Biopharm. 58(2), 253-263 (2004
-
(2004)
Eur. J. Pharm. Biopharm
, vol.58
, Issue.2
, pp. 253-263
-
-
Bernkop-Schnürch, A.1
Krauland, A.H.2
Leitner, V.M.3
Palmberger, T.4
-
53
-
-
16244418685
-
Current strategies used to enhance the paracellular transport of therapeutic polypeptides across the intestinal epithelium
-
Salamat-Miller N, Johnston TP. Current strategies used to enhance the paracellular transport of therapeutic polypeptides across the intestinal epithelium. Int. J. Pharm. 294, 201-216 (2005
-
(2005)
Int. J. Pharm
, vol.294
, pp. 201-216
-
-
Salamat-Miller, N.1
Johnston, T.P.2
-
54
-
-
52149119477
-
Protein and peptide drug delivery: Oral approaches
-
Shaji J, Patole V. Protein and peptide drug delivery: oral approaches. Indian J. Pharm. Sci. 70(3), 269-277 (2008
-
(2008)
Indian J. Pharm. Sci
, vol.70
, Issue.3
, pp. 269-277
-
-
Shaji, J.1
Patole, V.2
-
55
-
-
0017701219
-
Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol
-
Abuchowski A, van Es T, Palczuk NC, Davis FF. Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol. J. Biol. Chem. 252(11), 3578-3581 (1977
-
(1977)
J. Biol. Chem
, vol.252
, Issue.11
, pp. 3578-3581
-
-
Abuchowski, A.1
Van Es, T.2
Palczuk, N.C.3
Davis, F.F.4
-
56
-
-
0036379293
-
Oral insulin product hexyl-insulin monoconjugate 2 (HIM2) in type 1 diabetes mellitus: The glucose stabilization effects of HIM2
-
Clement S, Still JG, Kosutic G, McAllister RG. Oral insulin product hexyl-insulin monoconjugate 2 (HIM2) in type 1 diabetes mellitus: the glucose stabilization effects of HIM2. Diabetes Technol. Ther. 4(4), 459-466 (2002
-
(2002)
Diabetes Technol. Ther
, vol.4
, Issue.4
, pp. 459-466
-
-
Clement, S.1
Still, J.G.2
Kosutic, G.3
McAllister, R.G.4
-
57
-
-
0036105205
-
Development of oral insulin: Progress and current status
-
Gordon Still J. Development of oral insulin: progress and current status. Diabetes Metab. Res. Rev. 18(Suppl. 1), S29-S37 (2002
-
(2002)
Diabetes Metab. Res. Rev
, vol.18
, Issue.SUPPL. 1
-
-
Gordon Still, J.1
-
58
-
-
0347316399
-
Oral modified insulin (HIM2) in patients with type 1 diabetes mellitus: Results from a Phase I/II clinical trial
-
Clement S, Dandona P, Still JG, Kosutic G. Oral modified insulin (HIM2) in patients with type 1 diabetes mellitus: results from a Phase I/II clinical trial. Metabolism 53(1), 54-58 (2004
-
(2004)
Metabolism
, vol.53
, Issue.1
, pp. 54-58
-
-
Clement, S.1
Dandona, P.2
Still, J.G.3
Kosutic, G.4
-
60
-
-
77958084962
-
A dose range finding study of novel oral insulin (IN-105) under fed conditions in type 2 diabetes mellitus subjects
-
Khedkar A, Iyer H, Anand A et al. A dose range finding study of novel oral insulin (IN-105) under fed conditions in type 2 diabetes mellitus subjects. Diabetes Obes. Metab. 12(8), 659-664 (2010
-
(2010)
Diabetes Obes. Metab
, vol.12
, Issue.8
, pp. 659-664
-
-
Khedkar, A.1
Iyer, H.2
Anand, A.3
-
61
-
-
75149183537
-
Chitosan-based delivery systems for protein therapeutics and antigens
-
Amidi M, Mastrobattista E, Jiskoot W, Hennink WE. Chitosan-based delivery systems for protein therapeutics and antigens. Adv. Drug Deliv. Rev. 62(1), 59-82 (2010
-
(2010)
Adv. Drug Deliv. Rev
, vol.62
, Issue.1
, pp. 59-82
-
-
Amidi, M.1
Mastrobattista, E.2
Jiskoot, W.3
Hennink, W.E.4
-
62
-
-
71849101103
-
Alternative routes of administration for systemic delivery of protein pharmaceuticals
-
Moeller E, Jorgensen L. Alternative routes of administration for systemic delivery of protein pharmaceuticals. Drug Discov. Today Technol. 5(2-3), e89-e94 (2008
-
(2008)
Drug Discov. Today Technol
, vol.5
, Issue.2-3
-
-
Moeller, E.1
Jorgensen, L.2
-
63
-
-
85157044818
-
Formulation, stability and characterisation of protein and peptide drugs
-
Mahato R (Ed.). CRC Press, FL, USA
-
Frokjaer S. Formulation, stability and characterisation of protein and peptide drugs. In: Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids. Mahato R (Ed.). CRC Press, FL, USA (2005
-
(2005)
Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids
-
-
Frokjaer, S.1
-
64
-
-
0032825974
-
Recent advances in buccal drug delivery and absorption - In vitro and in vivo studies
-
Junginger H. Recent advances in buccal drug delivery and absorption - in vitro and in vivo studies. J. Control. Release 62(1-2), 149-159 (1999
-
(1999)
J. Control. Release
, vol.62
, Issue.1-2
, pp. 149-159
-
-
Junginger, H.1
-
65
-
-
33746468534
-
Buccal bioadhesive drug delivery - A promising option for orally less efficient drugs
-
Sudhakar Y, Kuotsu K, Bandyopadhyay AK. Buccal bioadhesive drug delivery - a promising option for orally less efficient drugs. J. Control. Release 114(1), 15-40 (2006
-
(2006)
J. Control. Release
, vol.114
, Issue.1
, pp. 15-40
-
-
Sudhakar, Y.1
Kuotsu, K.2
Bandyopadhyay, A.K.3
-
67
-
-
0003070827
-
Structure and function of the oral mucosa and implications for drug delivery
-
Rathborne M (Ed. Marcel-Dekker, Inc., NY, USA )
-
Squier C, Wertz P. Structure and function of the oral mucosa and implications for drug delivery. In: Oral Mucosal Drug Delivery. Rathborne M (Ed.). Marcel-Dekker, Inc., NY, USA (1996
-
(1996)
Oral Mucosal Drug Delivery
-
-
Squier, C.1
Wertz, P.2
-
68
-
-
0035132416
-
Factors and strategies for improving buccal absorption of peptides
-
Veuillez F. Factors and strategies for improving buccal absorption of peptides. Eur. J. Pharm. Biopharm. 51(2), 93-109 (2001
-
(2001)
Eur. J. Pharm. Biopharm
, vol.51
, Issue.2
, pp. 93-109
-
-
Veuillez, F.1
-
69
-
-
79960086774
-
Advances in oral transmucosal drug delivery
-
Patel VF, Liu F, Brown MB. Advances in oral transmucosal drug delivery. J. Control. Release 53(2), 106-116 (2011
-
(2011)
J. Control. Release
, vol.53
, Issue.2
, pp. 106-116
-
-
Patel, V.F.1
Liu, F.2
Brown, M.B.3
-
70
-
-
0037148692
-
Peptidase activity on the surface of the porcine buccal mucosa
-
Walker G, Langoth N, Berknop-Schnurch A. Peptidase activity on the surface of the porcine buccal mucosa. Int. J. Pharm. 233(1-2), 141-147 (2002
-
(2002)
Int. J. Pharm
, vol.233
, Issue.1-2
, pp. 141-147
-
-
Walker, G.1
Langoth, N.2
Berknop-Schnurch, A.3
-
71
-
-
0032732323
-
Evaluation of a novel, natural oligosaccharide gum as a sustained-release and mucoadhesive component of calcitonin buccal tablets
-
Alur HH, Beal JD, Pather SI, Mitra AK, Johnston TP. Evaluation of a novel, natural oligosaccharide gum as a sustained-release and mucoadhesive component of calcitonin buccal tablets. J. Pharm. Sci. 88(12), 1313-1319 (1999
-
(1999)
J. Pharm. Sci
, vol.88
, Issue.12
, pp. 1313-1319
-
-
Alur, H.H.1
Beal, J.D.2
Pather, S.I.3
Mitra, A.K.4
Johnston, T.P.5
-
72
-
-
0037712690
-
Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery
-
Remuñán-López C, Portero A, Vila-Jato JL, Alonso MJ. Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery. J. Control. Release 55(2-3), 143-152 (1998
-
(1998)
J. Control. Release
, vol.55
, Issue.2-3
, pp. 143-152
-
-
Remuñán-López, C.1
Portero, A.2
Vila-Jato, J.L.3
Alonso, M.J.4
-
73
-
-
0033813758
-
Bioadhesive-based dosage forms: The next generation
-
Lee JW, Park JH, Robinson Jr. Bioadhesive-based dosage forms: the next generation. J. Pharm. Sci. 89(7), 850-866 (2000
-
(2000)
J. Pharm. Sci
, vol.89
, Issue.7
, pp. 850-866
-
-
Lee, J.W.1
Park, J.H.2
Robinson, J.R.3
-
74
-
-
34250891275
-
Mucoadhesive interactions of amphiphilic cationic copolymers based on [2-(methacryloyloxy) ethyl]trimethylammonium chloride
-
Fefelova NA, Nurkeeva ZS, Mun GA, Khutoryanskiy VV. Mucoadhesive interactions of amphiphilic cationic copolymers based on [2-(methacryloyloxy) ethyl]trimethylammonium chloride. Int. J. Pharm. 339(1-2), 25-32 (2007
-
(2007)
Int. J. Pharm
, vol.339
, Issue.1-2
, pp. 25-32
-
-
Fefelova, N.A.1
Nurkeeva, Z.S.2
Mun, G.A.3
Khutoryanskiy, V.V.4
-
75
-
-
0032507738
-
In vitro evaluation of the mucoadhesive properties of chitosan microspheres
-
He P, Davis S, Illum L. In vitro evaluation of the mucoadhesive properties of chitosan microspheres. Int. J. Pharm. 166(1), 75-88 (1998
-
(1998)
Int. J. Pharm
, vol.166
, Issue.1
, pp. 75-88
-
-
He, P.1
Davis, S.2
Illum, L.3
-
76
-
-
0033991816
-
Chitosan and its derivatives: Potential excipients for peroral peptide delivery systems
-
Bernkop-Schnürch A. Chitosan and its derivatives: potential excipients for peroral peptide delivery systems. Int. J. Pharm. 194(1), 1-13 (2000
-
(2000)
Int. J. Pharm
, vol.194
, Issue.1
, pp. 1-13
-
-
Bernkop-Schnürch, A.1
-
77
-
-
0034734982
-
Lectin-mediated mucosal delivery of drugs and microparticles
-
Clark MA, Hirst BH, Jepson MA. Lectin-mediated mucosal delivery of drugs and microparticles. Adv. Drug Deliv. Rev. 43(2-3), 207-223 (2000
-
(2000)
Adv. Drug Deliv. Rev
, vol.43
, Issue.2-3
, pp. 207-223
-
-
Clark, M.A.1
Hirst, B.H.2
Jepson, M.A.3
-
79
-
-
78149339756
-
The buccal mucosa as an alternative route for the systemic delivery of risperidone
-
Heemstra LB, Finnin BC, Nicolazzo JA. The buccal mucosa as an alternative route for the systemic delivery of risperidone. J. Pharm. Sci. 99(11), 4584-4592 (2010
-
(2010)
J. Pharm. Sci
, vol.99
, Issue.11
, pp. 4584-4592
-
-
Heemstra, L.B.1
Finnin, B.C.2
Nicolazzo, J.A.3
-
80
-
-
77953618655
-
Nanoparticles for local drug delivery to the oral mucosa: Proof of principle studies
-
Holpuch AS, Hummel GJ, Tong M et al. Nanoparticles for local drug delivery to the oral mucosa: proof of principle studies. Pharm. Res. 27(7), 1224-1236 (2010
-
(2010)
Pharm. Res
, vol.27
, Issue.7
, pp. 1224-1236
-
-
Holpuch, A.S.1
Hummel, G.J.2
Tong, M.3
-
81
-
-
84859436289
-
Development and characterisation of chitosan films impregnated with insulin loaded PEG-b-PLA nanoparticles (NPs): A potential approach for buccal delivery of macromolecules
-
Giovino C, Ayensu I, Tetteh J, Boateng JS. Development and characterisation of chitosan films impregnated with insulin loaded PEG-b-PLA nanoparticles (NPs): a potential approach for buccal delivery of macromolecules. Int. J. Pharm. 428(1-2), 143-151 (2012
-
(2012)
Int. J. Pharm
, vol.428
, Issue.1-2
, pp. 143-151
-
-
Giovino, C.1
Ayensu, I.2
Tetteh, J.3
Boateng, J.S.4
-
82
-
-
20444371579
-
Buccal penetration enhancers - How do they really work?
-
Nicolazzo JA, Reed BL, Finnin BC. Buccal penetration enhancers - how do they really work? J. Control. Release 105(1-2), 1-15 (2005
-
(2005)
J. Control. Release
, vol.105
, Issue.1-2
, pp. 1-15
-
-
Nicolazzo, J.A.1
Reed, B.L.2
Finnin, B.C.3
-
83
-
-
0029759228
-
In vivo buccal delivery of the peptide drug buserelin with glycodeoxycholate as an absorption enhancer in pigs
-
Hoogstraate AJ, Coos Verhoef J, Pijpers A et al. In vivo buccal delivery of the peptide drug buserelin with glycodeoxycholate as an absorption enhancer in pigs. Pharm. Res. 13(8), 1233-1237 (1996
-
(1996)
Pharm. Res
, vol.13
, Issue.8
, pp. 1233-1237
-
-
Hoogstraate, A.J.1
Coos Verhoef, J.2
Pijpers, A.3
-
84
-
-
84864604538
-
Modeling the oral cavity: In vitro and in vivo evaluations of buccal drug delivery systems
-
Patel VF, Liu F, Brown MB. Modeling the oral cavity: in vitro and in vivo evaluations of buccal drug delivery systems. J. Control. Release 161(3), 746-756 (2012
-
(2012)
J. Control. Release
, vol.161
, Issue.3
, pp. 746-756
-
-
Patel, V.F.1
Liu, F.2
Brown, M.B.3
-
85
-
-
0037459005
-
Nasal drug delivery - Possibilities, problems and solutions
-
Illum L. Nasal drug delivery - possibilities, problems and solutions. J. Control. Release 87(1-3), 187-198 (2003
-
(2003)
J. Control. Release
, vol.87
, Issue.1-3
, pp. 187-198
-
-
Illum, L.1
-
86
-
-
0033229947
-
Delivery of peptide and non-peptide drugs through the respiratory tract
-
Davis S. Delivery of peptide and non-peptide drugs through the respiratory tract. Pharm. Sci. Technol. Today 2(11), 450-456 (1999
-
(1999)
Pharm. Sci. Technol. Today
, vol.2
, Issue.11
, pp. 450-456
-
-
Davis, S.1
-
87
-
-
0034095651
-
Transport of drugs from the nasal cavity to the central nervous system
-
Illum L. Transport of drugs from the nasal cavity to the central nervous system. Eur. J. Pharm. Sci. 11, 1-18 (2000
-
(2000)
Eur. J. Pharm. Sci
, vol.11
, pp. 1-18
-
-
Illum, L.1
-
88
-
-
34248205304
-
Nasal drug delivery systemfactors affecting and applications
-
Jadhav K, Gambhire M, Shaikh I, Kadam V, Pisal S. Nasal drug delivery systemfactors affecting and applications. Curr. Drug Therapy 2, 27-38 (2007
-
(2007)
Curr. Drug Therapy
, vol.2
, pp. 27-38
-
-
Jadhav, K.1
Gambhire, M.2
Shaikh, I.3
Kadam, V.4
Pisal, S.5
-
89
-
-
3542998669
-
Nasal route and drug delivery systems
-
Türker S, Onur E, Ozer Y. Nasal route and drug delivery systems. Pharm. World Sci. 26(3), 137-142 (2004
-
(2004)
Pharm. World Sci
, vol.26
, Issue.3
, pp. 137-142
-
-
Türker, S.1
Onur, E.2
Ozer, Y.3
-
90
-
-
68649090916
-
Nanoparticles for direct nose-to-brain delivery of drugs
-
Mistry A, Stolnik S, Illum L. Nanoparticles for direct nose-to-brain delivery of drugs. Int. J. Pharm. 379, 146-157 (2009
-
(2009)
Int. J. Pharm
, vol.379
, pp. 146-157
-
-
Mistry, A.1
Stolnik, S.2
Illum, L.3
-
91
-
-
77950358719
-
Intranasal drug delivery: How, why and what for?
-
Pires A, Fortuna A, Alves G, Falcão A. Intranasal drug delivery: how, why and what for? J. Pharm. Pharm. Sci. 12(3), 288-311 (2009
-
(2009)
J. Pharm. Pharm. Sci
, vol.12
, Issue.3
, pp. 288-311
-
-
Pires, A.1
Fortuna, A.2
Alves, G.3
Falcão, A.4
-
92
-
-
70349556669
-
Nasal delivery of high molecular weight drugs
-
Ozsoy Y, Gungor S, Cevher E. Nasal delivery of high molecular weight drugs. Molecules 14, 3754-3779 (2009
-
(2009)
Molecules
, vol.14
, pp. 3754-3779
-
-
Ozsoy, Y.1
Gungor, S.2
Cevher, E.3
-
93
-
-
0025851808
-
The nasal mucocilliary clearance: Relevance to nasal drug delivery
-
Schipper N, Verhoef J, Merkus F. The nasal mucocilliary clearance: relevance to nasal drug delivery. Pharm. Res. 8, 807-814 (1991
-
(1991)
Pharm. Res
, vol.8
, pp. 807-814
-
-
Schipper, N.1
Verhoef, J.2
Merkus, F.3
-
94
-
-
0001782792
-
Anatomy and physiology
-
Naclerio R, Durham S, Mygind N (Eds Marcel-Dekker, Inc., NY, USA
-
Baroody F. Anatomy and physiology. In: Rhinitis: Mechanisms and Management. Naclerio R, Durham S, Mygind N (Eds). Marcel-Dekker, Inc., NY, USA (1999
-
(1999)
Rhinitis: Mechanisms and Management
-
-
Baroody, F.1
-
95
-
-
0002963196
-
Bioadhesive formulations for nasal peptide delivery
-
Mathiowitz E, Chickering D, Lehr CM (Eds Marcel- Dekker, Inc., NY, USA )
-
Illum L. Bioadhesive formulations for nasal peptide delivery In: Bioadhesive Drug Delivery Systems: Fundamentals, Novel Approaches and Development. Mathiowitz E, Chickering D, Lehr CM (Eds). Marcel- Dekker, Inc., NY, USA (1999
-
(1999)
Bioadhesive Drug Delivery Systems: Fundamentals, Novel Approaches and Development
-
-
Illum, L.1
-
96
-
-
0141872336
-
-
Pharmaceutical Formulation Development of Peptides and Proteins Frokjaer S, Hovgaard L (Eds). Taylor and Francis PA, USA
-
Ingemann M, Frokjaer S, Hovgaard L, Brøndsted H. Peptide and protein drug delivery systems for non-parenteral routes of administration. In: Pharmaceutical Formulation Development of Peptides and Proteins. Frokjaer S, Hovgaard L (Eds). Taylor and Francis, PA, USA (2000
-
(2000)
Peptide and protein drug delivery systems for non-parenteral routes of administration
-
-
Ingemann, M.1
Frokjaer, S.2
Hovgaard, L.3
Brøndsted, H.4
-
97
-
-
80054830004
-
Nasal drug delivery
-
Rathborne, M (Ed. Marcel-Dekker, Inc., NY, USA
-
Karla P, Deep K, Gaudana R, Mitra A. Nasal drug delivery In: Modified Release Drug Delivery Technology. Rathborne, M (Ed.). Marcel-Dekker, Inc., NY, USA (2008
-
(2008)
Modified Release Drug Delivery Technology
-
-
Karla, P.1
Deep, K.2
Gaudana, R.3
Mitra, A.4
-
98
-
-
0026586445
-
Drug metabolism in the nasal mucosa
-
Sarkar M. Drug metabolism in the nasal mucosa. Pharm. Res. 9, 1-9 (1992
-
(1992)
Pharm. Res
, vol.9
, pp. 1-9
-
-
Sarkar, M.1
-
99
-
-
33847073061
-
Pharmacokinetics and pharmacodynamics of sterylglucoside-modified liposomes for levonorgestrel delivery via nasal route
-
Ding WX, Qi XR, Fu Q, Piao HS. Pharmacokinetics and pharmacodynamics of sterylglucoside-modified liposomes for levonorgestrel delivery via nasal route. Drug Deliv. 14(2), 101-104 (2007
-
(2007)
Drug Deliv
, vol.14
, Issue.2
, pp. 101-104
-
-
Ding, W.X.1
Qi, X.R.2
Fu, Q.3
Piao, H.S.4
-
100
-
-
30644471588
-
Nasal delivery of insulin using bioadhesive chitosan gels
-
Varshosaz J, Sadrai H, Heidari A. Nasal delivery of insulin using bioadhesive chitosan gels. Drug Deliv. 13(1), 31-38 (2006
-
(2006)
Drug Deliv
, vol.13
, Issue.1
, pp. 31-38
-
-
Varshosaz, J.1
Sadrai, H.2
Heidari, A.3
-
101
-
-
33744797668
-
Aminated gelatin microspheres as a nasal delivery system for peptide drugs: Evaluation of in vitro release and in vivo insulin absorption in rats
-
Wang J, Tabata Y, Morimoto K. Aminated gelatin microspheres as a nasal delivery system for peptide drugs: evaluation of in vitro release and in vivo insulin absorption in rats. J. Control. Release 113(1), 31-37 (2006
-
(2006)
J. Control. Release
, vol.113
, Issue.1
, pp. 31-37
-
-
Wang, J.1
Tabata, Y.2
Morimoto, K.3
-
102
-
-
0026674499
-
Nasal membrane and intracellular protein and enzyme release by bile salts and bile salt-fatty acid mixed micelles: Correlation with facilitated drug transport
-
Shao Z, Mitra AK. Nasal membrane and intracellular protein and enzyme release by bile salts and bile salt-fatty acid mixed micelles: correlation with facilitated drug transport. Pharm. Res. 9(9), 1184-1189 (1992
-
(1992)
Pharm. Res
, vol.9
, Issue.9
, pp. 1184-1189
-
-
Shao, Z.1
Mitra, A.K.2
-
103
-
-
0026663934
-
Absorption enhancers in nasal insulin delivery and their influence on nasal ciliary functioning
-
Schipper N, Verhoef J, Romejin SG, Merkus F. Absorption enhancers in nasal insulin delivery and their influence on nasal ciliary functioning. J. Control. Release 21(1-3), 173-185 (1992
-
(1992)
J. Control. Release
, vol.21
, Issue.1-3
, pp. 173-185
-
-
Schipper, N.1
Verhoef, J.2
Romejin, S.G.3
Merkus, F.4
-
104
-
-
34447528700
-
Muco-adhesive multivesicular liposomes as an effective carrier for transmucosal insulin delivery
-
Jain AK, Chalasani KB, Khar RK, Ahmed FJ, Diwan PV. Muco-adhesive multivesicular liposomes as an effective carrier for transmucosal insulin delivery. J. Drug Target. 15(6), 417-427 (2007
-
(2007)
J. Drug Target
, vol.15
, Issue.6
, pp. 417-427
-
-
Jain, A.K.1
Chalasani, K.B.2
Khar, R.K.3
Ahmed, F.J.4
Diwan, P.V.5
-
105
-
-
0035189175
-
Enhancement of nasal absorption of calcitonin loaded in liposomes
-
Law SL, Huang KJ, Chou VH, Cherng JY. Enhancement of nasal absorption of calcitonin loaded in liposomes. J. Liposome Res. 11(2-3), 165-174 (2001
-
(2001)
J. Liposome Res
, vol.11
, Issue.2-3
, pp. 165-174
-
-
Law, S.L.1
Huang, K.J.2
Chou, V.H.3
Cherng, J.Y.4
-
106
-
-
0026520761
-
Effects of proteolytic enzyme inhibitors as absorption enhancers on the transdermal iontophoretic delivery of calcitonin in rats
-
Morimoto K, Iwakura Y, Nakatani E, Miyazaki M, Tojima H. Effects of proteolytic enzyme inhibitors as absorption enhancers on the transdermal iontophoretic delivery of calcitonin in rats. J. Pharm. Pharmacol. 44(3), 216-218 (1992
-
(1992)
J. Pharm. Pharmacol
, vol.44
, Issue.3
, pp. 216-218
-
-
Morimoto, K.1
Iwakura, Y.2
Nakatani, E.3
Miyazaki, M.4
Tojima, H.5
-
107
-
-
0025088495
-
Nasal absorption enhancers for biosynthetic human growth hormone in rats
-
O'Hagan DT, Critchley H, Farraj NF et al. Nasal absorption enhancers for biosynthetic human growth hormone in rats. Pharm. Res. 7(7), 772-776 (1990
-
(1990)
Pharm. Res
, vol.7
, Issue.7
, pp. 772-776
-
-
O'Hagan, D.T.1
Critchley, H.2
Farraj, N.F.3
-
108
-
-
12344281758
-
Commercial challenges of protein drug delivery
-
Brown L. Commercial challenges of protein drug delivery. Expert Opin. Drug Del. 2(1), 29-42 (2005
-
(2005)
Expert Opin. Drug Del
, vol.2
, Issue.1
, pp. 29-42
-
-
Brown, L.1
-
109
-
-
0346104870
-
Absorption enhancers in pulmonary protein delivery
-
Hussain A, Arnold JJ, Khan MA, Ahsan F. Absorption enhancers in pulmonary protein delivery. J. Control. Release 94 (1), 15-24 (2004
-
(2004)
J. Control. Release
, vol.94
, Issue.1
, pp. 15-24
-
-
Hussain, A.1
Arnold, J.J.2
Khan, M.A.3
Ahsan, F.4
-
110
-
-
34147126384
-
Recent advances in protein and peptide drug delivery system
-
Malik DK, Baboota S, Ahuja A, Hasan S, Ali J. Recent advances in protein and peptide drug delivery system. Curr. Drug Deliv. 4, 141-151 (2007
-
(2007)
Curr. Drug Deliv
, vol.4
, pp. 141-151
-
-
Malik, D.K.1
Baboota, S.2
Ahuja, A.3
Hasan, S.4
Ali, J.5
-
111
-
-
84862109704
-
Noninvasive routes of proteins and peptides drug delivery
-
Jitendra, Sharma PK, Bansal S, Banik A. Noninvasive routes of proteins and peptides drug delivery. Indian J. Pharm. Sci. 73(4), 367-375 (2011
-
(2011)
Indian J. Pharm. Sci
, vol.73
, Issue.4
, pp. 367-375
-
-
Jitendra Sharma, P.K.1
Bansal, S.2
Banik, A.3
-
112
-
-
36849085410
-
Pfizer dumps Exubera
-
Mack GS. Pfizer dumps Exubera. Nat. Biotechnol. 25, 1331-1332 (2007
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 1331-1332
-
-
Mack, G.S.1
-
113
-
-
67349152120
-
Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery
-
Chono S, Fukuchi R, Seki T, Morimoto K. Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery. J. Control. Release 137(2), 104-109 (2009
-
(2009)
J. Control. Release
, vol.137
, Issue.2
, pp. 104-109
-
-
Chono, S.1
Fukuchi, R.2
Seki, T.3
Morimoto, K.4
-
114
-
-
0029055776
-
Susceptibility of insulin to proteolysis in rat lung homogenate and its protection from proteolysis by various protease inhibitors
-
Fukuda Y, Tsuji T, Fujita T, Yamamoto A, Muranishi S. Susceptibility of insulin to proteolysis in rat lung homogenate and its protection from proteolysis by various protease inhibitors. Biol. Pharm. Bull. 18(6), 891-894 (1995
-
(1995)
Biol. Pharm. Bull
, vol.18
, Issue.6
, pp. 891-894
-
-
Fukuda, Y.1
Tsuji, T.2
Fujita, T.3
Yamamoto, A.4
Muranishi, S.5
-
115
-
-
0027955697
-
Absorption enhancement of intrapulmonary administered insulin by various absorption enhancers and protease inhibitors in rats
-
Yamamoto A, Umemori S, Muranishi S. Absorption enhancement of intrapulmonary administered insulin by various absorption enhancers and protease inhibitors in rats. J. Pharm. Pharmacol. 46(1), 14-18 (1994
-
(1994)
J. Pharm. Pharmacol
, vol.46
, Issue.1
, pp. 14-18
-
-
Yamamoto, A.1
Umemori, S.2
Muranishi, S.3
-
116
-
-
84862327411
-
Enhanced pulmonary absorption of recombinant human insulin by pulmonary surfactant and phospholipid hexadecanol tyloxapol through Calu-3 monolayers
-
Zheng J, Zheng Y, Chen J et al. Enhanced pulmonary absorption of recombinant human insulin by pulmonary surfactant and phospholipid hexadecanol tyloxapol through Calu-3 monolayers. Pharmazie 67(5), 448-451 (2012
-
(2012)
Pharmazie
, vol.67
, Issue.5
, pp. 448-451
-
-
Zheng, J.1
Zheng, Y.2
Chen, J.3
-
117
-
-
77955903375
-
Technosphere® insulin: Defining the role of technosphere particles at the cellular level
-
Angelo R, Rousseau BS, Grant M, Leone-Bay A, Richardson P. Technosphere® insulin: defining the role of technosphere particles at the cellular level. J. Diabetes Sci. Technol. 3(3), 545-554 (2009
-
(2009)
J. Diabetes Sci. Technol
, vol.3
, Issue.3
, pp. 545-554
-
-
Angelo, R.1
Rousseau, B.S.2
Grant, M.3
Leone-Bay, A.4
Richardson, P.5
-
118
-
-
79952200239
-
Pharmacokinetic characterization of the novel pulmonary delivery excipient fumaryl diketopiperazine
-
Potocka E, Cassidy JP, Haworth P, Heuman D, van Marle S, Baughman RA Jr. Pharmacokinetic characterization of the novel pulmonary delivery excipient fumaryl diketopiperazine. J. Diabetes Sci. Technol. 4(5), 1164-1173 (2010
-
(2010)
J. Diabetes Sci. Technol
, vol.4
, Issue.5
, pp. 1164-1173
-
-
Potocka, E.1
Cassidy, J.P.2
Haworth, P.3
Heuman, D.4
Van Marle, S.5
Baughman Jr., R.A.6
-
120
-
-
84868031494
-
Technosphere insulin effectively controls postprandial glycemia in patients with type 2 diabetes mellitus
-
Zisser H, Jovanovic L, Markova K et al. Technosphere insulin effectively controls postprandial glycemia in patients with type 2 diabetes mellitus. Diabetes Technol. Ther. 14(11), 997-1001 (2012
-
(2012)
Diabetes Technol. Ther
, vol.14
, Issue.11
, pp. 997-1001
-
-
Zisser, H.1
Jovanovic, L.2
Markova, K.3
-
121
-
-
0036145578
-
Interleukin-2 liposomes for primary immune deficiency using the aerosol route
-
Ten RM, Anderson PM, Zein NN, Temesgen Z, Clawson ML, Weiss W. Interleukin-2 liposomes for primary immune deficiency using the aerosol route. Int. Immunopharmacol. 2, 333-344 (2002
-
(2002)
Int. Immunopharmacol
, vol.2
, pp. 333-344
-
-
Ten, R.M.1
Anderson, P.M.2
Zein, N.N.3
Temesgen, Z.4
Clawson, M.L.5
Weiss, W.6
-
122
-
-
84856597241
-
Pulmonary delivery of elcatonin using surface-modified liposomes to improve systemic absorption: Polyvinyl alcohol with a hydrophobic anchor and chitosan oligosaccharide as effective surface modifiers
-
Murata M, Nakano K, Tahara K, Tozuka Y, Takeuchi H. Pulmonary delivery of elcatonin using surface-modified liposomes to improve systemic absorption: polyvinyl alcohol with a hydrophobic anchor and chitosan oligosaccharide as effective surface modifiers. Eur. J. Pharm. Biopharm. 80(2), 340-346 (2012
-
(2012)
Eur. J. Pharm. Biopharm
, vol.80
, Issue.2
, pp. 340-346
-
-
Murata, M.1
Nakano, K.2
Tahara, K.3
Tozuka, Y.4
Takeuchi, H.5
-
123
-
-
84869773544
-
Liposomal delivery of proteins and peptides
-
Swaminathan J, Ehrhardt C. Liposomal delivery of proteins and peptides. Expert Opin. Drug Deliv. 9(12) 1489-1503 (2012
-
(2012)
Expert Opin. Drug Deliv
, vol.9
, Issue.12
, pp. 1489-1503
-
-
Swaminathan, J.1
Ehrhardt, C.2
-
124
-
-
0025825296
-
Degradation of insulin by trypsin and a-chymotrypsin
-
Schilling RJ, Mitra AK. Degradation of insulin by trypsin and a-chymotrypsin, Pharm. Res. 8, 721-727 (1991
-
(1991)
Pharm. Res
, vol.8
, pp. 721-727
-
-
Schilling, R.J.1
Mitra, A.K.2
-
125
-
-
0035901722
-
The effect of absorption enhancers on the initial degradation kinetics of insulin by alpha-chymotrypsin
-
Radwan MA, Aboul-Enein HY. The effect of absorption enhancers on the initial degradation kinetics of insulin by alpha-chymotrypsin. Int. J. Pharm. 217(1-2), 111-120 (2001
-
(2001)
Int. J. Pharm
, vol.217
, Issue.1-2
, pp. 111-120
-
-
Radwan, M.A.1
Aboul-Enein, H.Y.2
-
126
-
-
0029818353
-
Effects of enzyme inhibitors and insulin concentration on transepithelial transport of insulin in rats
-
Bai JP, Chang LL. Effects of enzyme inhibitors and insulin concentration on transepithelial transport of insulin in rats. J. Pharm. Pharmacol. 48(10), 1078-1082 (1996
-
(1996)
J. Pharm. Pharmacol
, vol.48
, Issue.10
, pp. 1078-1082
-
-
Bai, J.P.1
Chang, L.L.2
-
127
-
-
0019157951
-
Cytotoxic effects of protease inhibitors on human cells part 2. Effect of Elastatinal
-
Yagi T, Ishizaki K, Takebe H. Cytotoxic effects of protease inhibitors on human cells part 2. Effect of Elastatinal. Cancer Lett. 10, 301-307 (1980
-
(1980)
Cancer Lett
, vol.10
, pp. 301-307
-
-
Yagi, T.1
Ishizaki, K.2
Takebe, H.3
-
128
-
-
0027534406
-
Evidence for the role of a cathepsin D-like activity in the release of Gal beta 1-4GlcNAc alpha 2-6sialyltransferase from rat and mouse liver in whole-cell systems
-
McCaffrey G, Jamieson JC. Evidence for the role of a cathepsin D-like activity in the release of Gal beta 1-4GlcNAc alpha 2-6sialyltransferase from rat and mouse liver in whole-cell systems. Comp. Biochem. Physiol. B 104, 91-94 (1993
-
(1993)
Comp. Biochem. Physiol. B
, vol.104
, pp. 91-94
-
-
McCaffrey, G.1
Jamieson, J.C.2
-
129
-
-
0034306493
-
The scope and potential of vaginal drug delivery
-
Vermani K, Garg S. The scope and potential of vaginal drug delivery. Pharm. Sci. Technol. Today 3, 359-364 (2000
-
(2000)
Pharm. Sci. Technol. Today
, vol.3
, pp. 359-364
-
-
Vermani, K.1
Garg, S.2
-
130
-
-
26844560127
-
The use of mucoadhesive polymers in vaginal delivery
-
Valenta C. The use of mucoadhesive polymers in vaginal delivery. Adv. Drug Del. Rev. 57, 1692-1712 (2005
-
(2005)
Adv. Drug Del. Rev
, vol.57
, pp. 1692-1712
-
-
Valenta, C.1
-
131
-
-
0020416221
-
Vaginal absorption of a potent luteinizing hormone-releasing hormone analog (leuprolide) in rats I: Absorption by various routes and absorption enhancement
-
Okada H, Yamazaki I, Ogawa Y, Hirai S, Yashiki T, Mima H. Vaginal absorption of a potent luteinizing hormone-releasing hormone analog (leuprolide) in rats I: absorption by various routes and absorption enhancement. J. Pharm. Sci. 71(12), 1367-1371 (1982
-
(1982)
J. Pharm. Sci
, vol.71
, Issue.12
, pp. 1367-1371
-
-
Okada, H.1
Yamazaki, I.2
Ogawa, Y.3
Hirai, S.4
Yashiki, T.5
Mima, H.6
-
133
-
-
0035173648
-
Comparison of vaginal aminopeptidase enzymatic activities in various animals and in humans
-
Acartürk F, Parlatan Z, Saracoǧlu O. Comparison of vaginal aminopeptidase enzymatic activities in various animals and in humans. J. Pharm. Pharmacol. 53(11), 1499-1504 (2001
-
(2001)
J. Pharm. Pharmacol
, vol.53
, Issue.11
, pp. 1499-1504
-
-
Acartürk, F.1
Parlatan, Z.2
Saracoǧlu, O.3
-
134
-
-
0012700801
-
Vaginal delivery of calcitonin by hyaluronic acid formulations
-
Mathiowitz E, Chickering DE, Lehr CM (Eds Marcel-Dekker, Inc., NY, USA 563-599
-
Richardson JL, Armstrong TI. Vaginal delivery of calcitonin by hyaluronic acid formulations. In: Bioadhesive Drug Delivery Systems - Fundamentals, Novel Approaches and Development. Mathiowitz E, Chickering DE, Lehr CM (Eds). Marcel-Dekker, Inc., NY, USA 563-599 (1999
-
(1999)
Bioadhesive Drug Delivery Systems - Fundamentals, Novel Approaches and Development
-
-
Richardson, J.L.1
Armstrong, T.I.2
-
135
-
-
0029552071
-
Development of luteinizing hormone releasing hormone (LH-RH) delivery systems for vaginal mucosal route
-
Han K, Park JS, Chung YB, Jeong NJ, Park HB, Robinson Jr. Development of luteinizing hormone releasing hormone (LH-RH) delivery systems for vaginal mucosal route. Arch. Pharm. Res. 18, 325-331 (1995
-
(1995)
Arch. Pharm. Res
, vol.18
, pp. 325-331
-
-
Han, K.1
Park, J.S.2
Chung, Y.B.3
Jeong, N.J.4
Park, H.B.5
Robinson, J.R.6
-
136
-
-
0019975945
-
Effective vaginal absorption of insulin in diabetic rats and rabbits using polyacrylic acid aqueous gel bases
-
Morimoto K, Takeeda T, Nakamoto Y, Morisaka K. Effective vaginal absorption of insulin in diabetic rats and rabbits using polyacrylic acid aqueous gel bases. Int. J. Pharm. 12, 107-111 (1982
-
(1982)
Int. J. Pharm
, vol.12
, pp. 107-111
-
-
Morimoto, K.1
Takeeda, T.2
Nakamoto, Y.3
Morisaka, K.4
-
137
-
-
27644512131
-
Niosomes with sorbitan monoester as a carrier for vaginal delivery of insulin: Studies in rats
-
Ning M, Guo Y, Pan H, Yu H, Gu Z. Niosomes with sorbitan monoester as a carrier for vaginal delivery of insulin: studies in rats. Drug Deliv. 12(6), 399-407 (2005
-
(2005)
Drug Deliv
, vol.12
, Issue.6
, pp. 399-407
-
-
Ning, M.1
Guo, Y.2
Pan, H.3
Yu, H.4
Gu, Z.5
-
138
-
-
79960306877
-
Niosomes: A controlled and novel drug delivery system
-
Rajera R, Nagpal K, Singh SK, Mishra DN. Niosomes: a controlled and novel drug delivery system. Biol. Pharm. Bull. 34(7), 945-953 (2011
-
(2011)
Biol. Pharm. Bull
, vol.34
, Issue.7
, pp. 945-953
-
-
Rajera, R.1
Nagpal, K.2
Singh, S.K.3
Mishra, D.N.4
-
139
-
-
84867319576
-
Vaginal DNA vaccination against infectious diseases transmitted through the vagina
-
Kanazawa T, Takashima Y, Okada H. Vaginal DNA vaccination against infectious diseases transmitted through the vagina. Front. Biosci. (Elite Ed.) 4, 2340-2353 (2012
-
(2012)
Front. Biosci. (Elite Ed)
, vol.4
, pp. 2340-2353
-
-
Kanazawa, T.1
Takashima, Y.2
Okada, H.3
-
140
-
-
84860760141
-
Characterisation of protein stability in rod-insert vaginal rings
-
Pattani A, Lowry D, Curran RM et al. Characterisation of protein stability in rod-insert vaginal rings. Int. J. Pharm. 430(1-2), 89-97 (2012
-
(2012)
Int. J. Pharm
, vol.430
, Issue.1-2
, pp. 89-97
-
-
Pattani, A.1
Lowry, D.2
Curran, R.M.3
-
141
-
-
0342424651
-
Systemic delivery of peptide-based pharmaceuticals
-
Marcel-Dekker, Inc., NY, USA
-
Chien, Y. Systemic delivery of peptide-based pharmaceuticals. In: Novel Drug Delivery Systems. Marcel-Dekker, Inc., NY, USA (1992
-
(1992)
Novel Drug Delivery Systems
-
-
Chien, Y.1
-
142
-
-
0031563894
-
Peptide drug delivery: Colonic and rectal absorption
-
Mackay M, Philips J, Hastewell J. Peptide drug delivery: colonic and rectal absorption. Adv. Drug Deliv. 28, 253-273 (1997
-
(1997)
Adv. Drug Deliv
, vol.28
, pp. 253-273
-
-
Mackay, M.1
Philips, J.2
Hastewell, J.3
-
143
-
-
26844567547
-
-
Biological Barriers To Protein Delivery Audus KL, Raub TJ (Eds). Plenum Press, NY, USA
-
Muranshi S, Yamamoto A, Okada H. Rectal and vaginal absorption of peptides and proteins. In: Biological Barriers To Protein Delivery. Audus KL, Raub TJ (Eds). Plenum Press, NY, USA (1993
-
(1993)
Rectal and Vaginal Absorption of Peptides and Proteins
-
-
Muranshi, S.1
Yamamoto, A.2
Okada, H.3
-
144
-
-
0032963526
-
Relative hypoglycemia of rectal insulin suppositories containing deoxycholic acid, sodium taurocholate, polycarbophil, and their combinations in diabetic rabbits
-
Hosny E. Relative hypoglycemia of rectal insulin suppositories containing deoxycholic acid, sodium taurocholate, polycarbophil, and their combinations in diabetic rabbits. Drug Dev. Ind. Pharm. 25(6), 745-752 (1999
-
(1999)
Drug Dev. Ind. Pharm
, vol.25
, Issue.6
, pp. 745-752
-
-
Hosny, E.1
-
145
-
-
0034752744
-
Effect of different bile salts on the relative hypoglycemia of witepsol W35 suppositories containing insulin in diabetic Beagle dogs
-
Hosny E, Al-Shora H, Elmazar M. Effect of different bile salts on the relative hypoglycemia of witepsol W35 suppositories containing insulin in diabetic Beagle dogs. Drug Dev. Ind. Pharm. 27(8), 837-845 (2001
-
(2001)
Drug Dev. Ind. Pharm
, vol.27
, Issue.8
, pp. 837-845
-
-
Hosny, E.1
Al-Shora, H.2
Elmazar, M.3
-
146
-
-
84867838466
-
Approaches for breaking the barriers of drug permeation through transdermal drug delivery
-
Alexander A, Dwivedi S, Ajazuddin et al. Approaches for breaking the barriers of drug permeation through transdermal drug delivery. J. Control. Release 164(1), 26-40 (2012
-
(2012)
J. Control. Release
, vol.164
, Issue.1
, pp. 26-40
-
-
Alexander, A.1
Ajazuddin, D.S.2
-
147
-
-
28044473874
-
Emerging strategies for the transdermal delivery of peptide and protein drugs
-
Schuetz YB, Naik A, Guy RH, Kalia YN. Emerging strategies for the transdermal delivery of peptide and protein drugs. Expert Opin. Drug Deliv. 2, 533-548 (2005
-
(2005)
Expert Opin. Drug Deliv
, vol.2
, pp. 533-548
-
-
Schuetz, Y.B.1
Naik, A.2
Guy, R.H.3
Kalia, Y.N.4
-
148
-
-
53549130424
-
Proteins and peptides: Strategies for delivery to and across the skin
-
Benson HA, Namjoshi S. Proteins and peptides: strategies for delivery to and across the skin. J. Pharm. Sci. 97(9), 3591-3610 (2008
-
(2008)
J. Pharm. Sci
, vol.97
, Issue.9
, pp. 3591-3610
-
-
Benson, H.A.1
Namjoshi, S.2
-
149
-
-
70349122971
-
Transdermal drug delivery: Evolving technologies and expanding opportunities
-
Aggarwal G, Garg A, Dhawan S. Transdermal drug delivery: evolving technologies and expanding opportunities. Indian J. Pharm. Ed. Res. 43, 251-259 (2009
-
(2009)
Indian J. Pharm. Ed. Res
, vol.43
, pp. 251-259
-
-
Aggarwal, G.1
Garg, A.2
Dhawan, S.3
-
150
-
-
73949137818
-
Penetration of nanoparticles and nanomaterials in the skin: Fiction or reality? J
-
Baroli B. Penetration of nanoparticles and nanomaterials in the skin: fiction or reality? J. Pharm. Sci. 99, 21-50 (2010
-
(2010)
Pharm. Sci
, vol.99
, pp. 21-50
-
-
Baroli, B.1
-
151
-
-
79955023808
-
Stratum corneum permeation and percutaneous drug delivery of hydrophilic molecules enhanced by cryopneumatic and photopneumatic technologies
-
Sun F, Anderson R, Aguilar G. Stratum corneum permeation and percutaneous drug delivery of hydrophilic molecules enhanced by cryopneumatic and photopneumatic technologies. J. Drugs Derm. 9, 1528-1530 (2010
-
(2010)
J. Drugs Derm
, vol.9
, pp. 1528-1530
-
-
Sun, F.1
Anderson, R.2
Aguilar, G.3
-
152
-
-
55049116362
-
Applications of ultrasonic skin permeation in transdermal drug delivery
-
Smith NB. Applications of ultrasonic skin permeation in transdermal drug delivery. Expert Opin. Drug Del. 5, 1107-1120 (2008
-
(2008)
Expert Opin. Drug Del
, vol.5
, pp. 1107-1120
-
-
Smith, N.B.1
-
153
-
-
78649956855
-
Low-frequency sonophoresis: Application to the transdermal delivery of macromolecules and hydrophilic drugs
-
Polat BE, Blankschtein D, Langer R. Low-frequency sonophoresis: application to the transdermal delivery of macromolecules and hydrophilic drugs. Expert Opin. Drug Del. 7, 1415-1432 (2010
-
(2010)
Expert Opin. Drug Del
, vol.7
, pp. 1415-1432
-
-
Polat, B.E.1
Blankschtein, D.2
Langer, R.3
-
154
-
-
0034902043
-
Novel mechanisms and devices to enable successful transdermal drug delivery
-
Barry BW. Novel mechanisms and devices to enable successful transdermal drug delivery. Eur. J. Pharm. Sci. 14, 101-114 (2001
-
(2001)
Eur. J. Pharm. Sci
, vol.14
, pp. 101-114
-
-
Barry, B.W.1
-
155
-
-
0037240324
-
Transdermal delivery of nalbuphine and its prodrugs by electroporation
-
Sung KC, Fang JY, Wang JJ, Hu OY. Transdermal delivery of nalbuphine and its prodrugs by electroporation. Eur. J. Pharm. Sci. 18, 63-70 (2003
-
(2003)
Eur. J. Pharm. Sci
, vol.18
, pp. 63-70
-
-
Sung, K.C.1
Fang, J.Y.2
Wang, J.J.3
Hu, O.Y.4
-
156
-
-
77955271877
-
Effect of controlled laser microporation on drug transport kinetics into and across the skin
-
Bachhav YG, Summer S, Heinrich A, Bragagna T, Bohler C, Kalia YN. Effect of controlled laser microporation on drug transport kinetics into and across the skin. J. Control. Release 146, 31-36 (2010
-
(2010)
J. Control. Release
, vol.146
, pp. 31-36
-
-
Bachhav, Y.G.1
Summer, S.2
Heinrich, A.3
Bragagna, T.4
Bohler, C.5
Kalia, Y.N.6
-
157
-
-
77951434882
-
Microneedle-based drug delivery systems: Microfabrication, drug delivery, and safety
-
Donnelly RF, Raj Singh TR, Woolfson AD. Microneedle-based drug delivery systems: microfabrication, drug delivery, and safety. Drug Deliv. 17(4), 187-207 (2010
-
(2010)
Drug Deliv
, vol.17
, Issue.4
, pp. 187-207
-
-
Donnelly, R.F.1
Raj Singh, T.R.2
Woolfson, A.D.3
-
158
-
-
78651261187
-
Design, optimization and characterisation of polymeric microneedle arrays prepared by a novel laser-based micromoulding technique
-
Donnelly RF, Majithiya R, Singh TR et al. Design, optimization and characterisation of polymeric microneedle arrays prepared by a novel laser-based micromoulding technique. Pharm. Res. 28(1), 41-57 (2011
-
(2011)
Pharm. Res
, vol.28
, Issue.1
, pp. 41-57
-
-
Donnelly, R.F.1
Majithiya, R.2
Singh, T.R.3
-
159
-
-
3042809905
-
Transdermal delivery of insulin using microneedles in vivo
-
Martanto W, Davis SP, Holiday NR, Wang J, Gill HS, Prausnitz MR. Transdermal delivery of insulin using microneedles in vivo. Pharm. Res. 21(6), 947-952 (2004
-
(2004)
Pharm. Res
, vol.21
, Issue.6
, pp. 947-952
-
-
Martanto, W.1
Davis, S.P.2
Holiday, N.R.3
Wang, J.4
Gill, H.S.5
Prausnitz, M.R.6
-
160
-
-
84863578185
-
Out-of-plane, high strength, polymer microneedles for transdermal drug delivery
-
Chaudhri BP, Ceyssens F, Neves HP, La Manna A, Van Hoof C, Puers R. Out-of-plane, high strength, polymer microneedles for transdermal drug delivery. Conf. Proc. IEEE Eng. Med. Biol. Soc. 3680-3683 (2011
-
(2011)
Conf. Proc IEEE Eng. Med. Biol. Soc
, pp. 3680-3683
-
-
Chaudhri, B.P.1
Ceyssens, F.2
Neves, H.P.3
La Manna, A.4
Van Hoof, C.5
Puers, R.6
-
161
-
-
84859501688
-
Dissolving polymeric microneedle arrays for electrically assisted transdermal drug delivery
-
Garland MJ, Caffarel-Salvador E, Migalska K, Woolfson AD, Donnelly RF. Dissolving polymeric microneedle arrays for electrically assisted transdermal drug delivery. J. Control. Release 159(1), 52-59 (2012
-
(2012)
J. Control. Release
, vol.159
, Issue.1
, pp. 52-59
-
-
Garland, M.J.1
Caffarel-Salvador, E.2
Migalska, K.3
Woolfson, A.D.4
Donnelly, R.F.5
-
162
-
-
0036007129
-
Macroflux microprojection array patch technology: A new and efficient approach for intracutaneous immunization
-
Matriano JA, Cormier M, Johnson J et al. Macroflux microprojection array patch technology: a new and efficient approach for intracutaneous immunization. Pharm. Res. 19(1), 63-70 (2002
-
(2002)
Pharm. Res
, vol.19
, Issue.1
, pp. 63-70
-
-
Matriano, J.A.1
Cormier, M.2
Johnson, J.3
-
163
-
-
3042556333
-
Transdermal delivery of desmopressin using a coated microneedle array patch system
-
Cormier M, Johnson B, Ameri M et al. Transdermal delivery of desmopressin using a coated microneedle array patch system. J. Control. Release 97(3), 503-511 (2004
-
(2004)
J. Control. Release
, vol.97
, Issue.3
, pp. 503-511
-
-
Cormier, M.1
Johnson, B.2
Ameri, M.3
-
164
-
-
79952287383
-
Dissolving microneedle patch for transdermal delivery of human growth hormone
-
Lee JW, Choi SO, Felner EI, Prausnitz MR. Dissolving microneedle patch for transdermal delivery of human growth hormone. Small 7(4), 531-539 (2011
-
(2011)
Small
, vol.7
, Issue.4
, pp. 531-539
-
-
Lee, J.W.1
Choi, S.O.2
Felner, E.I.3
Prausnitz, M.R.4
-
165
-
-
3042809905
-
Transdermal delivery of insulin using microneedles in vivo
-
Martanto W, Davis SP, Holiday NR, Wang J, Gill HS, Prausnitz MR. Transdermal delivery of insulin using microneedles in vivo. Pharm. Res. 21(6), 947-952 (2004
-
(2004)
Pharm. Res
, vol.21
, Issue.6
, pp. 947-952
-
-
Martanto, W.1
Davis, S.P.2
Holiday, N.R.3
Wang, J.4
Gill, H.S.5
Prausnitz, M.R.6
-
166
-
-
84861963363
-
Microneedle delivery of plasmid DNA to living human skin: Formulation coating, skin insertion and gene expression
-
Pearton M, Saller V, Coulman SA et al. Microneedle delivery of plasmid DNA to living human skin: formulation coating, skin insertion and gene expression. J. Control. Release 160(3), 561-569 (2012
-
(2012)
J. Control. Release
, vol.160
, Issue.3
, pp. 561-569
-
-
Pearton, M.1
Saller, V.2
Coulman, S.A.3
-
167
-
-
84863490212
-
DNA vaccination in the skin using microneedles improves protection against inf luenza
-
Song JM, Kim YC, O E, Compans RW, Prausnitz MR, Kang SM. DNA vaccination in the skin using microneedles improves protection against inf luenza. Mol. Ther. 20(7), 1472-1480 (2012
-
(2012)
Mol. Ther
, vol.20
, Issue.7
, pp. 1472-1480
-
-
Song, J.M.1
Kim, Y.C.2
Compans, R.W.3
Prausnitz, M.R.4
Kang, S.M.5
-
168
-
-
84862629947
-
A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens
-
Matsuo K, Yokota Y, Zhai Y et al. A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens. J. Control. Release 161(1), 10-17 (2012
-
(2012)
J. Control. Release
, vol.161
, Issue.1
, pp. 10-17
-
-
Matsuo, K.1
Yokota, Y.2
Zhai, Y.3
-
169
-
-
79960557083
-
Infusion pressure and pain during microneedle injection into skin of human subjects
-
2011
-
Gupta J, Park SS, Bondy B, Felner EI, Prausnitz MR. Infusion pressure and pain during microneedle injection into skin of human subjects. Biomaterials 32(28), 6823-6231 (2011
-
Biomaterials
, vol.32
, Issue.28
, pp. 6823-6231
-
-
Gupta, J.1
Park, S.S.2
Bondy, B.3
Felner, E.I.4
Prausnitz, M.R.5
-
170
-
-
79961173516
-
Laser-engineered dissolving microneedle arrays for transdermal macromolecular drug delivery
-
Migalska K, Morrow DI, Garland MJ, Thakur R, Woolfson AD, Donnelly RF. Laser-engineered dissolving microneedle arrays for transdermal macromolecular drug delivery. Pharm. Res. 28(8), 1919-1930 (2011
-
(2011)
Pharm. Res
, vol.28
, Issue.8
, pp. 1919-1930
-
-
Migalska, K.1
Morrow, D.I.2
Garland, M.J.3
Thakur, R.4
Woolfson, A.D.5
Donnelly, R.F.6
-
171
-
-
84870624248
-
Hydrogel forming microneedle arrays for enhanced transdermal drug delivery
-
Donnelly RF, Thakur RRS, Garland MJ et al. Hydrogel forming microneedle arrays for enhanced transdermal drug delivery. Adv. Funct. Mat. 22, 4879-4890 (2012
-
(2012)
Adv. Funct. Mat
, vol.22
, pp. 4879-4890
-
-
Donnelly, R.F.1
Rrs, T.2
Garland, M.J.3
-
172
-
-
41849128858
-
Electrically responsive smart hydrogels in drug delivery: A review
-
Kulkarni RV, Biswanath S. Electrically responsive smart hydrogels in drug delivery: a review. J. Appl. Biomater. Biomech. 5(3), 125-139 (2007
-
(2007)
J. Appl. Biomater. Biomech
, vol.5
, Issue.3
, pp. 125-139
-
-
Kulkarni, R.V.1
Biswanath, S.2
-
175
-
-
85157052609
-
-
Frost Sullivan Accessed on 8 January 2013
-
Frost, Sullivan. Merrion pharmaceuticals (2008). www.merrionpharma.com/ archive/FandS-MP-051108.pdf (Accessed on 8 January 2013
-
(2008)
Merrion Pharmaceuticals
-
-
|