Characterisation of protein stability in rod-insert vaginal rings

International Journal of Pharmaceutics

Volumn 430, Issue 1-2, 2012, Pages 89-97

  Pattani, Aditya ^a   Lowry, Deborah ^a   Curran, Rhonda M ^a   McGrath, Stephanie ^a   Kett, Vicky L ^a   Andrews, Gavin P ^a   Malcolm, R Karl ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Freeze dried protein; Protein aggregation; Protein stability; Vaginal delivery; Vaginal ring

Indexed keywords

BOVINE SERUM ALBUMIN; HYDROXYPROPYLMETHYLCELLULOSE; TREHALOSE;

ARTICLE; BACTERIAL COUNT; CIRCULAR DICHROISM; COMPRESSION; CONFORMATIONAL TRANSITION; FREEZE DRYING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LOW TEMPERATURE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PATHOGEN LOAD; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN STABILITY; ROD INSERT VAGINAL RING; THERMOGRAVIMETRY; TURBIDIMETRY; VAGINA RING;

ADMINISTRATION, INTRAVAGINAL; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG STABILITY; ELASTOMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EQUIPMENT CONTAMINATION; EQUIPMENT DESIGN; EXCIPIENTS; FEMALE; FREEZE DRYING; GELS; HUMANS; HUMIDITY; METHYLCELLULOSE; NEPHELOMETRY AND TURBIDIMETRY; POLYSORBATES; PROTEIN CONFORMATION; PROTEIN STABILITY; SERUM ALBUMIN, BOVINE; SOLUBILITY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; THERMOGRAVIMETRY; TIME FACTORS; TREHALOSE; VACCINES;

EID: 84860760141     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.03.036     Document Type: Article

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