Pulmonary delivery of elcatonin using surface-modified liposomes to improve systemic absorption: Polyvinyl alcohol with a hydrophobic anchor and chitosan oligosaccharide as effective surface modifiers

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 80, Issue 2, 2012, Pages 340-346

  Murata, Mitsutaka ^a   Nakano, Koji ^a   Tahara, Kohei ^a   Tozuka, Yuichi ^a   Takeuchi, Hirofumi ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Chitosan; Elcatonin; Liposomes; Pulmonary administration; PVA; Surface modification

Indexed keywords

CHITOSAN; ELCATONIN; LIPOSOME; OLIGOSACCHARIDE; POLYVINYL ALCOHOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CELL INTERACTION; CELL VIABILITY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXICITY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; FEASIBILITY STUDY; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; LUNG FLUID; LUNG PARENCHYMA; NONHUMAN; RAT; TIGHT JUNCTION;

ANIMALS; CALCITONIN; CELL LINE, TUMOR; CHITOSAN; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEASIBILITY STUDIES; HUMANS; LIPOSOMES; LUNG; MALE; OLIGOSACCHARIDES; POLYVINYL ALCOHOL; RATS; RATS, WISTAR; TIME FACTORS; TISSUE DISTRIBUTION; TOXICITY TESTS;

EID: 84856597241     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.10.011     Document Type: Conference Paper

References (24)

1. F.Y. Liu, Z. Shao, D.O. Kildsig, and A.K. Mitra Pulmonary delivery of free and liposomal insulin Pharm. Res. 10 1993 228 232 (Pubitemid 23041736)
2. J.S. Patton Mechanisms of macromolecule absorption by the lungs Adv. Drug Deliv. Rev. 19 1996 3 36 (Pubitemid 26167852)
3. R.U. Agu, M.I. Ugwoke, M. Armand, R. Kinget, and N. Verbeke The lung as a route for systemic delivery of therapeutic proteins and peptides Resp. Res. 2 2001 198 209 (Pubitemid 34187927)
4. R. Siekmeier, and G. Scheuch Treatment of systemic diseases by inhalation of biomolecule aerosols J. Physiol. Pharmacol. 60 2009 15 26
5. B. Stark, F. Andreae, W. Mosgoeller, M. Edetsberger, E. Gaubitzer, G. Koehler, and R. Prass Liposomal vasoactive intestinal peptide for lung application: protection from proteolytic degradation Eur. J. Pharm. Biopharm. 70 2008 153 164
6. L. Zhao, Y. Ye, J. Li, and Y. Wei Preparation and the in vivo evaluation of paclitaxel liposomes for lung targeting delivery in dogs J. Pharm. Pharmacol. 63 2011 80 86
7. A. Makhlof, S. Fujimoto, Y. Tozuka, and H. Takeuchi In vitro and in vivo evaluation of WGA-carbopol modified liposomes as carriers for oral peptide delivery Eur. J. Pharm. Biopharm. 77 2011 216 224
8. Y. Yoshizawa, Y. Kono, Ken-ichi Ogawara, T. Kimura, and K. Higaki PEG liposomalization of paclitaxel improved its in vivo disposition and anti-tumor efficacy Int. J. Pharm. 412 2011 132 141
9. H. Takeuchi, H. Kojima, H. Yamamoto, and Y. Kawashima Polymer coating of liposomes with a modified polyvinyl alcohol and their systemic circulation and RES uptake in rats J. Control. Release 68 2000 195 205 (Pubitemid 30488897)
10. H. Takeuchi, H. Kojima, T. Toyoda, H. Yamamoto, T. Hino, and Y. Kawashima Prolonged circulation time of doxorubicin-loaded liposomes coated with a modified polyvinyl alcohol after intravenous injection in rats Eur. J. Pharm. Biopharm. 48 1999 123 129 (Pubitemid 29401988)
11. H. Takeuchi, H. Yamamoto, T. Toyoda, H. Toyobuku, T. Hino, and Y. Kawashima Physical stability of size controlled small unilameller liposomes coated with a modified polyvinyl alcohol Int. J. Pharm. 164 1998 103 111 (Pubitemid 28160102)
12. H. Takeuchi, J. Thongborisute, Y. Matsui, H. Sugihara, H. Yamamoto, and Y. Kawashima Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems Adv. Drug Deliv. Rev. 57 2005 1583 1594 (Pubitemid 41443471)
13. H. Tekeuchi, H. Yamamoto, T. Toyoda, and Y. Kawashima Mucoadhesion of polymer-coated liposomes to rat intestine in vitro Chem. Pharm. Bull. 42 1994 1954 1956 (Pubitemid 24315522)
14. C.-M. Lehr, J.A. Bouwstra, E.H. Schacht, and H.E. Junginger In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers Int. J. Pharm. 78 1992 43 48
15. G. Siligardi, B. Samori, S. Melandri, M. Visconti, and A.F. Drake Correlations between biological activities and conformational properties for human, salmon, eel, porcine, and Elcatnin elucidated by CD spectroscopy Eur. J. Biochem. 221 1994 1117 1125 (Pubitemid 24146216)
16. M. Izume, and A. Ohtakara Preparation of d-glucosamine oligosaccharides by the enzymatic hydrolysis of chitosan Agric. Biol. Chem. 51 1987 1189 1191
17. C.I. Grainger, L.L. Greenwell, D.J. Lockley, G.P. Martin, and B. Forbes Culture of Calu-3 cells at the air interface provides a representative model of the airway epithelial barrier Pharm. Res. 23 2006 1482 1490 (Pubitemid 43993811)
18. W. Ho, and A. Furst Intratracheal instillation method for mouse lungs Oncology 27 1973 385 393
19. K. Yamada, M. Odomi, N. Okada, T. Fujita, and A. Yamamoto Chitosan oligomers as potential and safe absorption enhancers for improving the pulmonary absorption of interferon-α in rats J. Pharm. Sci. 94 2005 2432 2440 (Pubitemid 43081940)
20. V. Dodane, M.A. Khan, and J.R. Merwin Effect of chitosan on epithelial permeability and structure Int. J. Pharm. 182 1999 21 32 (Pubitemid 29229791)
21. A. Grenha, C.I. Grainger, L.A. Dailey, B. Seijo, G.P. Martin, C. Remunan-Lopez, and B. Forbes Chitosan nanoparticles are compatible with respiratory epithelial cells in vitro Eur. J. Pharm. Sci. 31 2007 73 84 (Pubitemid 46660576)
22. R.F. Henderson Use of bronchoalveolar lavage to detect lung damage Environ. Health Perspect. 56 1984 115 129 (Pubitemid 14070485)
23. I.M. van der Lubben, J.C. Verhoef, G. Borchard, and H.E. Junginger Chitosan and its derivatives in mucosal drug and vaccine delivery Eur. J. Pharm. Sci. 14 2001 201 207 (Pubitemid 32884316)
24. K. Nakano, Y. Tozuka, and H. Takeuchi Effect of surface properties of liposomes coated with a modified polyvinyl alcohol (PVA-R) on the interaction with macrophage cells Int. J. Pharm. 354 2008 174 179 (Pubitemid 351400326)