메뉴 건너뛰기




Volumn 43, Issue 3, 2009, Pages 251-259

Transdermal drug delivery: Evolving technologies and expanding opportunities

Author keywords

Electroporation; Iontophoresis; Microneedle technology; Needleless injections; Pressure waves; Radiofrequency microchannels; Sonophoresis; Transdermal drug delivery

Indexed keywords

ANTIINFLAMMATORY AGENT; DRUG CARRIER; ETHOSOME; FENTANYL; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 70349122971     PISSN: 00195464     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (76)
  • 1
    • 1242308254 scopus 로고    scopus 로고
    • Current status and future potential of transdermal drug delivery
    • Prausnitz MR, Mitragotri S, Langer R. Current status and future potential of transdermal drug delivery. Nat Rev Drug Discov 2004;3(2):115-124 (Pubitemid 38239773)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.2 , pp. 115-124
    • Prausnitz, M.R.1    Mitragotri, S.2    Langer, R.3
  • 3
    • 33846156172 scopus 로고    scopus 로고
    • Four myths about transdermal drug delivery
    • Gorden RD, Peterson TA. Four myths about transdermal drug delivery. Drug Del Technol 2003;3:1-7.
    • (2003) Drug del Technol , vol.3 , pp. 1-7
    • Gorden, R.D.1    Peterson, T.A.2
  • 4
    • 12344296656 scopus 로고    scopus 로고
    • Transdermal drug delivery: Past, Present, Future
    • Scheindlin. Transdermal drug delivery: Past, Present, Future. Molecular Interventions 2004;4(6):308-312
    • (2004) Molecular Interventions , vol.4 , Issue.6 , pp. 308-312
    • Scheindlin1
  • 5
    • 0036331403 scopus 로고    scopus 로고
    • Polymers in transdermal drug delivery systems
    • [serial online] [cited 2008 jan 15];62-78. Available from
    • Kandavilli S, Nair V, Panchagnula R. Polymers in transdermal drug delivery systems. Pharm Technol [serial online] 2002 [cited 2008 jan 15];62-78. Available from: URL: www.pharmtech.com.
    • (2002) Pharm Technol
    • Kandavilli, S.1    Nair, V.2    Panchagnula, R.3
  • 6
    • 70349086778 scopus 로고    scopus 로고
    • Advances in transdermal technologies: Transdermal delivery takes up once forbidden compounds, reviving markets and creating formulation opportunities
    • [serial online] [cited 2008 jan 15];1-5. Available from
    • Rios M. Advances in transdermal technologies: transdermal delivery takes up once forbidden compounds, reviving markets and creating formulation opportunities. Pharm Technol [serial online] 2007 [cited 2008 jan 15];1-5. Available from: URL: www.pharmtech.com.
    • (2007) Pharm Technol
    • Rios, M.1
  • 7
    • 33645286192 scopus 로고    scopus 로고
    • Dermal and transdermal drug delivery systems: Current and future prospects
    • Brown MB, Martin GP, Jones SA, Akomeah FK. Dermal and transdermal drug delivery systems: Current and future prospects. Drug Deliv 2006;13(3):175-187
    • (2006) Drug Deliv , vol.13 , Issue.3 , pp. 175-187
    • Brown, M.B.1    Martin, G.P.2    Jones, S.A.3    Akomeah, F.K.4
  • 8
    • 5444241167 scopus 로고    scopus 로고
    • Emerging technologies in transdermal therapeutics
    • Meidan VM, Michniak BB. Emerging technologies in transdermal therapeutics. Am J Ther 2004;11:312-316
    • (2004) Am J Ther , vol.11 , pp. 312-316
    • Meidan, V.M.1    Michniak, B.B.2
  • 10
    • 0036355887 scopus 로고    scopus 로고
    • Optimizing delivery of therapeutics: Percutaneous technologies
    • Henzl MR. Optimizing delivery of therapeutics: percutaneous technologies. Bratisl Lek Listy 2002;103(4-5):144-151
    • (2002) Bratisl Lek Listy , vol.103 , Issue.4-5 , pp. 144-151
    • Henzl, M.R.1
  • 11
    • 70349108174 scopus 로고    scopus 로고
    • [online]. [cited 2008 july 15]. Available from
    • Frost and Sullivan. Rise of transdermal drug delivery technologies [online]. 2003 [cited 2008 july 15]. Available from: URL: http://www. Inpharmatechnologist.com/new/ng.asp?id=26435-rise-of-transdermal.
    • (2003) Rise of Transdermal Drug Delivery Technologies
    • Frost1    Sullivan2
  • 16
    • 0033996247 scopus 로고    scopus 로고
    • Ethosomes - Novel vesicular carriers for enhanced delivery: Characterization and skin penetration properties
    • DOI 10.1016/S0168-3659(99)00222-9, PII S0168365999002229
    • Touitou E, Dayan N, Bergelson I, Godin B Eliaz M. Ethosomes- Novel vesicular carriers for enhanced delivery: Characterization and skin penetration properties. J Control Release 2000;65:403-418 (Pubitemid 30122942)
    • (2000) Journal of Controlled Release , vol.65 , Issue.3 , pp. 403-418
    • Touitou, E.1    Dayan, N.2    Bergelson, L.3    Godin, B.4    Eliaz, M.5
  • 17
    • 33751231999 scopus 로고    scopus 로고
    • Transferosomes for transdermal drug delivery
    • Benson, Heather AE. Transferosomes for transdermal drug delivery. Expert Opin Drug Deliv 2006;3(6):727-737
    • (2006) Expert Opin Drug Deliv , vol.3 , Issue.6 , pp. 727-737
    • Benson1    Heather, A.E.2
  • 18
    • 38349149071 scopus 로고    scopus 로고
    • Iontophoretic transport across a multiple membrane system
    • Molokhia SA, Zhang Y, Higuchi WI, Li SK. Iontophoretic transport across a multiple membrane system. J Pharm Sci 2008;97:490-505.
    • (2008) J Pharm Sci , vol.97 , pp. 490-505
    • Molokhia, S.A.1    Zhang, Y.2    Higuchi, W.I.3    Li, S.K.4
  • 19
    • 0029041507 scopus 로고
    • Iontophoresis: Applications in transdermal medication delivery
    • Costello CT, Jeske AH. Iontophoresis: applications in transdermal medication delivery. Phys Ther 1995;75:554-563
    • (1995) Phys Ther , vol.75 , pp. 554-563
    • Costello, C.T.1    Jeske, A.H.2
  • 20
    • 0037436012 scopus 로고    scopus 로고
    • Optimization of aminolevulinic acid (ALA) delivery by iontophoresis
    • Lopez RFV, Bentley MVLB, Charro MBD, Guy RH. Optimization of aminolevulinic acid (ALA) delivery by iontophoresis. J Control Release 2003;88:65-70.
    • (2003) J Control Release , vol.88 , pp. 65-70
    • Lopez, R.F.V.1    Mvlb, B.2    Charro, M.B.D.3    Guy, R.H.4
  • 23
    • 37349085927 scopus 로고    scopus 로고
    • Vasodilator iontophoresis a possible new therapy for digital ischaemia in systemic sclerosis
    • Murray AK, Moore TL, King TA, Herrick AL. Vasodilator iontophoresis a possible new therapy for digital ischaemia in systemic sclerosis. Rheumatology (Oxford) 2008;47:76-79
    • (2008) Rheumatology (Oxford) , vol.47 , pp. 76-79
    • Murray, A.K.1    Moore, T.L.2    King, T.A.3    Herrick, A.L.4
  • 25
    • 37549003661 scopus 로고    scopus 로고
    • Mechanistic analysis of electroporation-induced cellular uptake of macromolecules
    • Zaharoff DA, Henshaw JW, Mossop B, Yuan F. Mechanistic analysis of electroporation-induced cellular uptake of macromolecules. Exp Biol Med (Maywood) 2008;233:94-105.
    • (2008) Exp Biol Med (Maywood) , vol.233 , pp. 94-105
    • Zaharoff, D.A.1    Henshaw, J.W.2    Mossop, B.3    Yuan, F.4
  • 26
    • 0033820934 scopus 로고    scopus 로고
    • Transdermal drug delivery using electroporation. II. Factors influencing skin reversibility in electroporative delivery of terazosin hydrochloride in hairless rats
    • DOI 10.1002/(SICI)1520-6017(200004)89:4<536::AID-JPS11>3.0.CO;2-O
    • Sharma A, Kara M, Smith FR, Krishnan TR. Transdermal drug delivery using electroporation. II. Factors influencing skin reversibiliy in electroporative delivery of terazosin hydrochloride in hairless rats. J Pharm Sci 2000;89(4):536-544 (Pubitemid 30690343)
    • (2000) Journal of Pharmaceutical Sciences , vol.89 , Issue.4 , pp. 536-544
    • Sharma, A.1    Kara, M.2    Smith, F.R.3    Krishnan, T.R.4
  • 27
    • 0037136038 scopus 로고    scopus 로고
    • Transdermal insulin delivery using lipid enhanced electroporation
    • DOI 10.1016/S0005-2736(02)00453-4, PII S0005273602004534
    • Sen A, Daly ME, Hui SW. Transdermal insulin delivery using lipid enhanced electroporation. Biochim Biophys Acta 2002;1564:5-8. (Pubitemid 34717862)
    • (2002) Biochimica et Biophysica Acta - Biomembranes , vol.1564 , Issue.1 , pp. 5-8
    • Sen, A.1    Daly, M.E.2    Hui, S.W.3
  • 31
    • 16244412915 scopus 로고    scopus 로고
    • Skin targeted DNA vaccine delivery using electroporation in rabbits - I: Efficacy
    • DOI 10.1016/j.ijpharm.2004.12.014
    • Medi BM, Hoselton S, Marepalli RB, Singh J. Skin targeted DNA vaccine delivery using electroportation in rabbits- I: Efficacy. Int J Pharm 2005;294(1-2):53-63. (Pubitemid 40462322)
    • (2005) International Journal of Pharmaceutics , vol.294 , Issue.1-2 , pp. 53-63
    • Medi, B.M.1    Hoselton, S.2    Marepalli, R.B.3    Singh, J.4
  • 32
    • 0037472111 scopus 로고    scopus 로고
    • Radiofrequency-driven skin microchanneling as a new way for electrically assisted transdermal delivery of hydrophilic drugs
    • Sintov AC. Radiofrequency-driven skin microchanneling as a new way for electrically assisted transdermal delivery of hydrophilic drugs. J Control Release 2003;89:311-320
    • (2003) J Control Release , vol.89 , pp. 311-320
    • Sintov, A.C.1
  • 35
    • 0037945771 scopus 로고    scopus 로고
    • Ultrasound enhanced transdermal transport
    • Merino G, Kalia YN, Guy RH. Ultrasound enhanced transdermal transport. J Pharm Sci 2003;92:1125-1137
    • (2003) J Pharm Sci , vol.92 , pp. 1125-1137
    • Merino, G.1    Kalia, Y.N.2    Guy, R.H.3
  • 36
    • 39049193701 scopus 로고    scopus 로고
    • Transdermal drug delivery using ultrasound therapy, understanding and critical analysis
    • Sivakumar M, Tachibana K, Pandit AB, Yasui K, Tuziuti K, Towata A, et al. Transdermal drug delivery using ultrasound therapy, understanding and critical analysis. Cell Mol Biol 2005;51:767-784
    • (2005) Cell Mol Biol , vol.51 , pp. 767-784
    • Sivakumar, M.1    Tachibana, K.2    Pandit, A.B.3    Yasui, K.4    Tuziuti, K.5    Towata, A.6
  • 38
    • 1542358753 scopus 로고    scopus 로고
    • Transdermal drug delivery with a pressure wave
    • DOI 10.1016/j.addr.2003.10.031, PII S0169409X03002370
    • Doukas AG, Kollias N. Transdermal drug delivery with a pressure wave. Adv Drug Deliv Rev 2004;56(5):559-579 (Pubitemid 38326933)
    • (2004) Advanced Drug Delivery Reviews , vol.56 , Issue.5 , pp. 559-579
    • Doukas, A.G.1    Kollias, N.2
  • 39
    • 33846542514 scopus 로고    scopus 로고
    • Assembled microneedle arrays enhance the transport of compounds varying over a large range of molecular weight across human dermatomed skin
    • DOI 10.1016/j.jconrel.2006.11.009, PII S0168365906006018
    • Verbaan FJ, Bal SM, Van den Berg DJ, Groenink WHH, Verpoorten H, Luttge R, et al. Assembled microneedle arrays enhance the transport of compounds varying over a large range of molecular weight across human dermatomed skin. J Control Release 2007;117:238-245 (Pubitemid 46161879)
    • (2007) Journal of Controlled Release , vol.117 , Issue.2 , pp. 238-245
    • Verbaan, F.J.1    Bal, S.M.2    Van Den Berg, D.J.3    Groenink, W.H.H.4    Verpoorten, H.5    Luttge, R.6    Bouwstra, J.A.7
  • 40
    • 1542358759 scopus 로고    scopus 로고
    • Microneedles for transdermal drug delivery
    • Prausnitz MR. Microneedles for transdermal drug delivery. Adv Drug Deliv Rev 2004;56(5):581-587
    • (2004) Adv Drug Deliv Rev , vol.56 , Issue.5 , pp. 581-587
    • Prausnitz, M.R.1
  • 43
    • 0034946760 scopus 로고    scopus 로고
    • Delivery of insulin by jet injection: Recent observations
    • DOI 10.1089/152091501300209598
    • Bremseth DL, Pass F. Delivery of insulin by jet injection: Recent observations. Diabetes Technol Ther 2001;3:225-232 (Pubitemid 32651958)
    • (2001) Diabetes Technology and Therapeutics , vol.3 , Issue.2 , pp. 225-232
    • Bremseth, D.L.1    Pass, F.2
  • 44
    • 0036086597 scopus 로고    scopus 로고
    • 'Needle-free' delivery of local anesthesia: A valuable option in pediatrics
    • Splinter WM. 'Needle-free' delivery of local anesthesia: a valuable option in pediatrics. Paediatr Drugs 2002;4(6):349-352
    • (2002) Paediatr Drugs , vol.4 , Issue.6 , pp. 349-352
    • Splinter, W.M.1
  • 46
    • 34047232233 scopus 로고    scopus 로고
    • The recent trend of transdermal drug delivery system development
    • DOI 10.1248/yakushi.127.655
    • Higo N. Recent trend of transdermal drug delivery system development. Yokugaku Zasshi 2007;127(4):655-662 (Pubitemid 46536538)
    • (2007) Yakugaku Zasshi , vol.127 , Issue.4 , pp. 655-662
    • Higo, N.1
  • 47
    • 34248233552 scopus 로고    scopus 로고
    • Influence of permeation enhancers on transdermal delivery of anemonia
    • Ning YM, Rao YF, Liang WQ. Influence of permeation enhancers on transdermal delivery of anemonia. Zhonqquo Zhong Yao Za Zhi 2007;32:393-396
    • (2007) Zhonqquo Zhong Yao Za Zhi , vol.32 , pp. 393-396
    • Ning, Y.M.1    Rao, Y.F.2    Liang, W.Q.3
  • 48
    • 0031445928 scopus 로고    scopus 로고
    • Testosterone skin permeation enhancement by menthol through formation of eutectic with the drug and interaction with lipid
    • Kaplun FW, Toitou E. Testosterone skin permeation enhancement by menthol through formation of eutectic with the drug and interaction with lipid. J Pharm Sci 1997;86:1394-1399
    • (1997) J Pharm Sci , vol.86 , pp. 1394-1399
    • Kaplun, F.W.1    Toitou, E.2
  • 49
    • 33847249544 scopus 로고    scopus 로고
    • Delivery of ethinylestradiol from film forming polymeric solutions across human epidermis in vitro and in vivo in pigs
    • DOI 10.1016/j.jconrel.2006.12.013, PII S0168365906007127
    • Zurdo SI, Franke P, Schaefer UF, Lehr CM. Delivery of ethinylestradiol from film forming polymeric solutions across human epidermis in vitro and in vivo in pigs. J Control Release 2007;118:196-203. (Pubitemid 46329735)
    • (2007) Journal of Controlled Release , vol.118 , Issue.2 , pp. 196-203
    • Schroeder, I.Z.1    Franke, P.2    Schaefer, U.F.3    Lehr, C.-M.4
  • 50
    • 70349126516 scopus 로고    scopus 로고
    • Effect of chemical enhancers on in vitro release of salbutamol sulfate from patches
    • Budhathoki U, Thapa P. Effect of chemical enhancers on in vitro release of salbutamol sulfate from patches. Kathmandu Univ J Sci Engg Technol 2005;1(1):1-8.
    • (2005) Kathmandu Univ J Sci Engg Technol , vol.1 , Issue.1 , pp. 1-8
    • Budhathoki, U.1    Thapa, P.2
  • 51
    • 23144440197 scopus 로고    scopus 로고
    • Transdermal delivery of zidovudine (AZT): The effects of vehicles, enhancers, and polymer membranes on permeation across cadaver pig skin
    • Suwanpidokkul N, Thongnopnua P, Umpryan K. Transdermal delivery of zidovudine (AZT): The effects of vehicles, enhancers and polymer membranes on permeation across cadaver pig skin. AAPS PharmSciTech 2004;5:Article 48. (Pubitemid 41086238)
    • (2004) AAPS PharmSciTech , vol.5 , Issue.3 , pp. 48
    • Suwanpidokkul, N.1    Thongnopnua, P.2    Umprayn, K.3
  • 52
    • 0031938795 scopus 로고    scopus 로고
    • Influence of the permeation enhancers 1-alkyl-2-pyrrolidones on permeant partitioning into the stratum corneum
    • DOI 10.1021/js970190k
    • Yoneto K, Li SK, Higuchi WI, Shimabaashi S. Influence of the permeation enhancers 1-alkyl-2-pyrrolidones on permeant partitioning into the stratum corneum. J Pharm Sci 1998;87:209-214 (Pubitemid 28081330)
    • (1998) Journal of Pharmaceutical Sciences , vol.87 , Issue.2 , pp. 209-214
    • Yoneto, K.1    Li, S.K.2    Higuchi, W.I.3    Shimabayashi, S.4
  • 53
    • 27744463374 scopus 로고    scopus 로고
    • Feasibility of transdermal delivery of fluoxetine
    • Parikh DK, Tapash KG. Feasibility of transdermal delivery of fluoxetine. AAPS PharmSciTech 2005;6(2):E144-9.
    • (2005) AAPS PharmSciTech , vol.6 , Issue.2
    • Parikh, D.K.1    Tapash, K.G.2
  • 54
    • 17044397634 scopus 로고    scopus 로고
    • Sorbitan monolaurate 20 as a potential skin permeation enhancer in transdermal patches
    • Mukherjee B, Kanupriya, Mahapatra S, Das S, Patra B. Sorbitan Monolaurate 20 as a potential skin permeation enhancer in transdermal patches. J Appl Res 2005;5(1):96-107. (Pubitemid 40503483)
    • (2005) Journal of Applied Research , vol.5 , Issue.1 , pp. 96-108
    • Mukherjee, B.1    Kanupriya2    Mahapatra, S.3    Das, S.4    Patra, B.5
  • 56
    • 35648983523 scopus 로고    scopus 로고
    • Effects of dimethylformamide and L-menthol permeation enhancers on transdermal delivery of quercetin
    • DOI 10.1080/10837450701481207, PII 783461391
    • Olivella MS, Lhez L, Pappano NB, Debattista NB. Effects of dimethylformamide and L-menthol permeation enhancers on transdermal delivery of quercetin. Pharm Dev Technol 2007;12:481-484 (Pubitemid 350034882)
    • (2007) Pharmaceutical Development and Technology , vol.12 , Issue.5 , pp. 481-484
    • Olivella, M.S.1    Lhez, L.2    Pappano, N.B.3    Debattista, N.B.4
  • 57
    • 8344269541 scopus 로고    scopus 로고
    • Formulation of an HPMC gel drug reservoir system with ethanol water as a solvent system and limonene as a permeation enhancer for enhancing in vitro transdermal delivery of nicorandil
    • Jayaaraam B, Bhaskar P. Formulation of an HPMC gel drug reservoir system with ethanol water as a solvent system and limonene as a permeation enhancer for enhancing in vitro transdermal delivery of nicorandil. J Pharmacol Biophysiol Res 2004;17:310-320
    • (2004) J Pharmacol Biophysiol Res , vol.17 , pp. 310-320
    • Jayaaraam, B.1    Bhaskar, P.2
  • 58
    • 34147124974 scopus 로고    scopus 로고
    • Formulation of transdermal drug delivery system: Matrix type, and selection of polymer- Their evaluation
    • DOI 10.2174/157016306780368135
    • Kaza R, Pitchaimani R. Formulation of transdermal drug delivery system: Matrix and selection of polymer-their evaluation. Curr Drug Discov Technol 2006;3:279-285 (Pubitemid 46572566)
    • (2006) Current Drug Discovery Technologies , vol.3 , Issue.4 , pp. 279-285
    • Kaza, R.1    Pitchaimani, R.2
  • 59
    • 0034003730 scopus 로고    scopus 로고
    • Enhancing effects of fatty acids on piroxicam permeation through rat skins
    • Shin SC, Shin EY, Cho CY. Enhancing effects of fatty acids on piroxicam permeation through rat skins. Drug Dev Ind Pharm 2000;26:563-566
    • (2000) Drug Dev Ind Pharm , vol.26 , pp. 563-566
    • Shin, S.C.1    Shin, E.Y.2    Cho, C.Y.3
  • 60
    • 0028958393 scopus 로고
    • Effect of various penetration enhancers using a novel skin alternative
    • Ogiso T, Iwaki M, Paku T. Effect of various penetration enhancers using a novel skin alternative. J Pharm Sci 1995;84:482-488
    • (1995) J Pharm Sci , vol.84 , pp. 482-488
    • Ogiso, T.1    Iwaki, M.2    Paku, T.3
  • 62
    • 0024521461 scopus 로고
    • Iontophoresis facilitated transdermal delivery of verapamil. 1. in vitro evaluation and mechanistic studies
    • Wearley L, Liu JC, Chien YW. Iontophoresis facilitated transdermal delivery of verapamil. 1. In vitro evaluation and mechanistic studies. J Control Release 1989;2:237-250
    • (1989) J Control Release , vol.2 , pp. 237-250
    • Wearley, L.1    Liu, J.C.2    Chien, Y.W.3
  • 63
    • 0028882735 scopus 로고
    • Transdermal iontophoresis and solute penetration across excised human skin
    • Singh P, Anbinker M, Smith GA, Zavortink D, Maibach HI. Transdermal iontophoresis and solute penetration across excised human skin. J Pharm Sci 1995;84:1342-1346
    • (1995) J Pharm Sci , vol.84 , pp. 1342-1346
    • Singh, P.1    Anbinker, M.2    Smith, G.A.3    Zavortink, D.4    Maibach, H.I.5
  • 65
    • 36048987306 scopus 로고    scopus 로고
    • Transdermal delivery of Clostridium botulinum toxin type a by pulsed current iontophoresis
    • DOI 10.1016/j.jaad.2007.08.037, PII S0190962207013229
    • Pacini S, Gulisano M, Punzi T, Ruggiero M. Transdermal delivery of Clostridium botulinum toxin type A by pulsed current iontophoresis. J Am Acad Dermatol 2007;57:1097-1099 (Pubitemid 350087356)
    • (2007) Journal of the American Academy of Dermatology , vol.57 , Issue.6 , pp. 1097-1099
    • Pacini, S.1    Gulisano, M.2    Punzi, T.3    Ruggiero, M.4
  • 66
  • 67
    • 63649116002 scopus 로고    scopus 로고
    • Investigation of drug delivery by iontophoresis in a surgical wound utilizing microdialysis
    • Holovics HJ, Anderson CR, Levine BS, Hui HW, Lunte, CE. Investigation of drug delivery by iontophoresis in a surgical wound utilizing microdialysis. Pharm Res 2007;24(1):1-4.
    • (2007) Pharm Res , vol.24 , Issue.1 , pp. 1-4
    • Holovics, H.J.1    Anderson, C.R.2    Levine, B.S.3    Hui, H.W.4    Lunte, C.E.5
  • 68
    • 0035337773 scopus 로고    scopus 로고
    • Topical delivery of lidocaine in healthy volunteers by electroporation, electroincorporation or iontophoresis: An evaluation of skin anaesthesia
    • Wallace MS. Topical delivery of lidocaine in healthy volunteers by electroporation, electroincorporation or iontophoresis: an evaluation of skin anaesthesia. Reg Anaesth Pain Med 2001;26:229-238
    • (2001) Reg Anaesth Pain Med , vol.26 , pp. 229-238
    • Wallace, M.S.1
  • 69
    • 0036789522 scopus 로고    scopus 로고
    • Saturated anionic phospholipids enhance transdermal transport by electroporation
    • Sen A, Zhao YL, Hui SW. Saturated anionic phospholipids enhance transdermal transport by electroporation. Biophys J 2002;83(4):2064-2073
    • (2002) Biophys J , vol.83 , Issue.4 , pp. 2064-2073
    • Sen, A.1    Zhao, Y.L.2    Hui, S.W.3
  • 71
    • 0032931085 scopus 로고    scopus 로고
    • Electroporation-mediated topical delivery of vitamin C for cosmetic applications
    • DOI 10.1016/S0302-4598(99)00026-4, PII S0302459899000264
    • Zang L, Lerner S, Rustrum WV, Hofmann GA. Electroporation mediated topical delivery of vitamin C for cosmetic applications. Bioelectrochem Bioenerget 1999;48:453-461 (Pubitemid 29225182)
    • (1999) Bioelectrochemistry and Bioenergetics , vol.48 , Issue.2 , pp. 453-461
    • Zhang, L.1    Lerner, S.2    Rustrum, W.V.3    Hofmann, G.A.4
  • 72
    • 0026721597 scopus 로고
    • Transdermal delivery of insulin to alloxan diabetic rabbits by ultrasound exposure
    • Tachibana K. Transdermal delivery of insulin to alloxan diabetic rabbits by ultrasound exposure. Pharm Res 1992;9:952-954
    • (1992) Pharm Res , vol.9 , pp. 952-954
    • Tachibana, K.1
  • 73
    • 0034813451 scopus 로고    scopus 로고
    • Transdermal delivery of heparin and low-molecular weight heparin using low-frequency ultrasound
    • DOI 10.1023/A:1010979010907
    • Mitragotri S, Kost J. Transdermal delivery of heparin and low molecular weight heparin using low frequency ultrasound. Pharm Res 2001;18:1151-1156 (Pubitemid 32900401)
    • (2001) Pharmaceutical Research , vol.18 , Issue.8 , pp. 1151-1156
    • Mitragotri, S.1    Kost, J.2
  • 74
    • 0036281760 scopus 로고    scopus 로고
    • Porous resins as a cavitation enhancer for low-frequency sonophoresis
    • DOI 10.1002/jps.10080
    • Terahara T, Mitragotri S, Langer R. Porous resins as cavitation enhancer for low frequency sonophoresis. J Pharm Sci 2002;91:753-759 (Pubitemid 34639638)
    • (2002) Journal of Pharmaceutical Sciences , vol.91 , Issue.3 , pp. 753-759
    • Terahara, T.1    Mitragotri, S.2    Langer, R.3
  • 75
    • 34249872741 scopus 로고    scopus 로고
    • Novel microneedle patches for active insulin delivery are efficient in maintaining glycaemic control: An initial comparison with subcutaneous administration
    • DOI 10.1007/s11095-007-9256-x
    • Nordquist L, Roxhed N, Griss P, Stemme G. Novel microneedle patches for active insulin delivery are efficient in maintaining glycaemic control: an initial comparison with subcutaneous administration. Pharm Res 2007;24:1381-1388 (Pubitemid 46870597)
    • (2007) Pharmaceutical Research , vol.24 , Issue.7 , pp. 1381-1388
    • Nordquist, L.1    Roxhed, N.2    Griss, P.3    Stemme, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.