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Volumn 8, Issue 5, 2013, Pages

MDA5 Plays a Crucial Role in Enterovirus 71 RNA-Mediated IRF3 Activation

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CYTOKINE; INTERFERON REGULATORY FACTOR 3; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5 PROTEIN; UNCLASSIFIED DRUG; VIRUS RNA; CASPASE; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; IFIH1 PROTEIN, HUMAN; IRF3 PROTEIN, HUMAN;

EID: 84877047634     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063431     Document Type: Article
Times cited : (77)

References (49)
  • 2
    • 0016257919 scopus 로고
    • An apparently new enterovirus isolated from patients with disease of the central nervous system
    • Schmidt NJ, Lennette EH, Ho HH, (1974) An apparently new enterovirus isolated from patients with disease of the central nervous system. J Infect Dis 129: 304-309.
    • (1974) J Infect Dis , vol.129 , pp. 304-309
    • Schmidt, N.J.1    Lennette, E.H.2    Ho, H.H.3
  • 4
    • 34547753377 scopus 로고    scopus 로고
    • Picornaviridae: The Virus ans Their Repliation
    • In: Knipe DM, Howley PM, editors, 5th ed. Philadelphia, PA, USA: Lippincott Williams & Wilkins
    • Racaniello VR (2007) Picornaviridae: The Virus ans Their Repliation. In: Knipe DM, Howley PM, editors. Fields Virology. 5th ed. Philadelphia, PA, USA: Lippincott Williams & Wilkins. pp. 796-839.
    • (2007) Fields Virology , pp. 796-839
    • Racaniello, V.R.1
  • 5
    • 0029557306 scopus 로고
    • Complete nucleotide sequence of enterovirus 71 is distinct from poliovirus
    • Brown BA, Pallansch MA, (1995) Complete nucleotide sequence of enterovirus 71 is distinct from poliovirus. Virus Res 39: 195-205.
    • (1995) Virus Res , vol.39 , pp. 195-205
    • Brown, B.A.1    Pallansch, M.A.2
  • 6
    • 0242268125 scopus 로고    scopus 로고
    • Enterovirus 71 contains a type I IRES element that functions when eukaryotic initiation factor eIF4G is cleaved
    • Thompson SR, Sarnow P, (2003) Enterovirus 71 contains a type I IRES element that functions when eukaryotic initiation factor eIF4G is cleaved. Virology 315: 259-266.
    • (2003) Virology , vol.315 , pp. 259-266
    • Thompson, S.R.1    Sarnow, P.2
  • 7
    • 0036271365 scopus 로고    scopus 로고
    • Infection with enterovirus 71 or expression of its 2A protease induces apoptotic cell death
    • Kuo RL, Kung SH, Hsu YY, Liu WT, (2002) Infection with enterovirus 71 or expression of its 2A protease induces apoptotic cell death. J Gen Virol 83: 1367-1376.
    • (2002) J Gen Virol , vol.83 , pp. 1367-1376
    • Kuo, R.L.1    Kung, S.H.2    Hsu, Y.Y.3    Liu, W.T.4
  • 8
    • 0020356106 scopus 로고
    • Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex
    • Etchison D, Milburn SC, Edery I, Sonenberg N, Hershey JW, (1982) Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex. J Biol Chem 257: 14806-14810.
    • (1982) J Biol Chem , vol.257 , pp. 14806-14810
    • Etchison, D.1    Milburn, S.C.2    Edery, I.3    Sonenberg, N.4    Hershey, J.W.5
  • 9
    • 70349659010 scopus 로고    scopus 로고
    • Enterovirus 71 3C protease cleaves a novel target CstF-64 and inhibits cellular polyadenylation
    • Weng KF, Li ML, Hung CT, Shih SR, (2009) Enterovirus 71 3C protease cleaves a novel target CstF-64 and inhibits cellular polyadenylation. PLoS Pathog 5: e1000593.
    • (2009) PLoS Pathog , vol.5
    • Weng, K.F.1    Li, M.L.2    Hung, C.T.3    Shih, S.R.4
  • 10
    • 0036057766 scopus 로고    scopus 로고
    • The 3C protease activity of enterovirus 71 induces human neural cell apoptosis
    • Li ML, Hsu TA, Chen TC, Chang SC, Lee JC, et al. (2002) The 3C protease activity of enterovirus 71 induces human neural cell apoptosis. Virology 293: 386-395.
    • (2002) Virology , vol.293 , pp. 386-395
    • Li, M.L.1    Hsu, T.A.2    Chen, T.C.3    Chang, S.C.4    Lee, J.C.5
  • 11
    • 36348940608 scopus 로고    scopus 로고
    • Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures
    • Randall RE, Goodbourn S, (2008) Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. J Gen Virol 89: 1-47.
    • (2008) J Gen Virol , vol.89 , pp. 1-47
    • Randall, R.E.1    Goodbourn, S.2
  • 12
    • 0037154176 scopus 로고    scopus 로고
    • mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties
    • Kang DC, Gopalkrishnan RV, Wu Q, Jankowsky E, Pyle AM, et al. (2002) mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties. Proc Natl Acad Sci U S A 99: 637-642.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 637-642
    • Kang, D.C.1    Gopalkrishnan, R.V.2    Wu, Q.3    Jankowsky, E.4    Pyle, A.M.5
  • 13
    • 3242813113 scopus 로고    scopus 로고
    • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, et al. (2004) The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 5: 730-737.
    • (2004) Nat Immunol , vol.5 , pp. 730-737
    • Yoneyama, M.1    Kikuchi, M.2    Natsukawa, T.3    Shinobu, N.4    Imaizumi, T.5
  • 14
    • 33646342149 scopus 로고    scopus 로고
    • Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
    • Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, et al. (2006) Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441: 101-105.
    • (2006) Nature , vol.441 , pp. 101-105
    • Kato, H.1    Takeuchi, O.2    Sato, S.3    Yoneyama, M.4    Yamamoto, M.5
  • 15
    • 39649092731 scopus 로고    scopus 로고
    • Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses
    • Takahasi K, Yoneyama M, Nishihori T, Hirai R, Kumeta H, et al. (2008) Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses. Mol Cell 29: 428-440.
    • (2008) Mol Cell , vol.29 , pp. 428-440
    • Takahasi, K.1    Yoneyama, M.2    Nishihori, T.3    Hirai, R.4    Kumeta, H.5
  • 16
    • 58049217490 scopus 로고    scopus 로고
    • RNA recognition and signal transduction by RIG-I-like receptors
    • Yoneyama M, Fujita T, (2009) RNA recognition and signal transduction by RIG-I-like receptors. Immunol Rev 227: 54-65.
    • (2009) Immunol Rev , vol.227 , pp. 54-65
    • Yoneyama, M.1    Fujita, T.2
  • 17
    • 24944538819 scopus 로고    scopus 로고
    • VISA is an adapter protein required for virus-triggered IFN-beta signaling
    • Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, et al. (2005) VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol Cell 19: 727-740.
    • (2005) Mol Cell , vol.19 , pp. 727-740
    • Xu, L.G.1    Wang, Y.Y.2    Han, K.J.3    Li, L.Y.4    Zhai, Z.5
  • 18
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
    • Seth RB, Sun L, Ea CK, Chen ZJ, (2005) Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122: 669-682.
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.K.3    Chen, Z.J.4
  • 19
    • 27144440476 scopus 로고    scopus 로고
    • Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
    • Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, et al. (2005) Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437: 1167-1172.
    • (2005) Nature , vol.437 , pp. 1167-1172
    • Meylan, E.1    Curran, J.2    Hofmann, K.3    Moradpour, D.4    Binder, M.5
  • 20
    • 27144440523 scopus 로고    scopus 로고
    • IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
    • Kawai T, Takahashi K, Sato S, Coban C, Kumar H, et al. (2005) IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol 6: 981-988.
    • (2005) Nat Immunol , vol.6 , pp. 981-988
    • Kawai, T.1    Takahashi, K.2    Sato, S.3    Coban, C.4    Kumar, H.5
  • 21
    • 0038363463 scopus 로고    scopus 로고
    • Triggering the interferon antiviral response through an IKK-related pathway
    • Sharma S, tenOever BR, Grandvaux N, Zhou GP, Lin R, et al. (2003) Triggering the interferon antiviral response through an IKK-related pathway. Science 300: 1148-1151.
    • (2003) Science , vol.300 , pp. 1148-1151
    • Sharma, S.1    tenOever, B.R.2    Grandvaux, N.3    Zhou, G.P.4    Lin, R.5
  • 22
    • 0038393016 scopus 로고    scopus 로고
    • IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
    • Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, et al. (2003) IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol 4: 491-496.
    • (2003) Nat Immunol , vol.4 , pp. 491-496
    • Fitzgerald, K.A.1    McWhirter, S.M.2    Faia, K.L.3    Rowe, D.C.4    Latz, E.5
  • 23
    • 33846307026 scopus 로고    scopus 로고
    • Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2
    • Saito T, Hirai R, Loo YM, Owen D, Johnson CL, et al. (2007) Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2. Proc Natl Acad Sci U S A 104: 582-587.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 582-587
    • Saito, T.1    Hirai, R.2    Loo, Y.M.3    Owen, D.4    Johnson, C.L.5
  • 24
    • 26844503987 scopus 로고    scopus 로고
    • The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I
    • Rothenfusser S, Goutagny N, DiPerna G, Gong M, Monks BG, et al. (2005) The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I. J Immunol 175: 5260-5268.
    • (2005) J Immunol , vol.175 , pp. 5260-5268
    • Rothenfusser, S.1    Goutagny, N.2    DiPerna, G.3    Gong, M.4    Monks, B.G.5
  • 25
    • 76549109497 scopus 로고    scopus 로고
    • LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses
    • Satoh T, Kato H, Kumagai Y, Yoneyama M, Sato S, et al. (2010) LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses. Proc Natl Acad Sci U S A 107: 1512-1517.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 1512-1517
    • Satoh, T.1    Kato, H.2    Kumagai, Y.3    Yoneyama, M.4    Sato, S.5
  • 26
    • 67749133995 scopus 로고    scopus 로고
    • 5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
    • Schmidt A, Schwerd T, Hamm W, Hellmuth JC, Cui S, et al. (2009) 5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I. Proc Natl Acad Sci U S A 106: 12067-12072.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12067-12072
    • Schmidt, A.1    Schwerd, T.2    Hamm, W.3    Hellmuth, J.C.4    Cui, S.5
  • 27
    • 33750984771 scopus 로고    scopus 로고
    • RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates
    • Pichlmair A, Schulz O, Tan CP, Naslund TI, Liljestrom P, et al. (2006) RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates. Science 314: 997-1001.
    • (2006) Science , vol.314 , pp. 997-1001
    • Pichlmair, A.1    Schulz, O.2    Tan, C.P.3    Naslund, T.I.4    Liljestrom, P.5
  • 28
    • 33750976374 scopus 로고    scopus 로고
    • 5′-Triphosphate RNA is the ligand for RIG-I
    • Hornung V, Ellegast J, Kim S, Brzozka K, Jung A, et al. (2006) 5′-Triphosphate RNA is the ligand for RIG-I. Science 314: 994-997.
    • (2006) Science , vol.314 , pp. 994-997
    • Hornung, V.1    Ellegast, J.2    Kim, S.3    Brzozka, K.4    Jung, A.5
  • 29
    • 70349728538 scopus 로고    scopus 로고
    • Activation of MDA5 requires higher-order RNA structures generated during virus infection
    • Pichlmair A, Schulz O, Tan CP, Rehwinkel J, Kato H, et al. (2009) Activation of MDA5 requires higher-order RNA structures generated during virus infection. J Virol 83: 10761-10769.
    • (2009) J Virol , vol.83 , pp. 10761-10769
    • Pichlmair, A.1    Schulz, O.2    Tan, C.P.3    Rehwinkel, J.4    Kato, H.5
  • 30
    • 46949097299 scopus 로고    scopus 로고
    • Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5
    • Kato H, Takeuchi O, Mikamo-Satoh E, Hirai R, Kawai T, et al. (2008) Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5. J Exp Med 205: 1601-1610.
    • (2008) J Exp Med , vol.205 , pp. 1601-1610
    • Kato, H.1    Takeuchi, O.2    Mikamo-Satoh, E.3    Hirai, R.4    Kawai, T.5
  • 31
    • 47949092573 scopus 로고    scopus 로고
    • Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA
    • Saito T, Owen DM, Jiang F, Marcotrigiano J, Gale M Jr, (2008) Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA. Nature 454: 523-527.
    • (2008) Nature , vol.454 , pp. 523-527
    • Saito, T.1    Owen, D.M.2    Jiang, F.3    Marcotrigiano, J.4    Gale Jr., M.5
  • 32
    • 80052077030 scopus 로고    scopus 로고
    • RNA structural domains in noncoding regions of the foot-and-mouth disease virus genome trigger innate immunity in porcine cells and mice
    • Rodriguez-Pulido M, Borrego B, Sobrino F, Saiz M, (2011) RNA structural domains in noncoding regions of the foot-and-mouth disease virus genome trigger innate immunity in porcine cells and mice. J Virol 85: 6492-6501.
    • (2011) J Virol , vol.85 , pp. 6492-6501
    • Rodriguez-Pulido, M.1    Borrego, B.2    Sobrino, F.3    Saiz, M.4
  • 33
    • 33744791510 scopus 로고    scopus 로고
    • Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
    • Gitlin L, Barchet W, Gilfillan S, Cella M, Beutler B, et al. (2006) Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc Natl Acad Sci U S A 103: 8459-8464.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 8459-8464
    • Gitlin, L.1    Barchet, W.2    Gilfillan, S.3    Cella, M.4    Beutler, B.5
  • 34
    • 72849147111 scopus 로고    scopus 로고
    • MDA5 and MAVS mediate type I interferon responses to coxsackie B virus
    • Wang JP, Cerny A, Asher DR, Kurt-Jones EA, Bronson RT, et al. (2010) MDA5 and MAVS mediate type I interferon responses to coxsackie B virus. J Virol 84: 254-260.
    • (2010) J Virol , vol.84 , pp. 254-260
    • Wang, J.P.1    Cerny, A.2    Asher, D.R.3    Kurt-Jones, E.A.4    Bronson, R.T.5
  • 35
    • 37349052379 scopus 로고    scopus 로고
    • Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity
    • Loo YM, Fornek J, Crochet N, Bajwa G, Perwitasari O, et al. (2008) Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity. J Virol 82: 335-345.
    • (2008) J Virol , vol.82 , pp. 335-345
    • Loo, Y.M.1    Fornek, J.2    Crochet, N.3    Bajwa, G.4    Perwitasari, O.5
  • 36
    • 73349104638 scopus 로고    scopus 로고
    • Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses
    • Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, et al. (2009) Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses. J Immunol 183: 6989-6997.
    • (2009) J Immunol , vol.183 , pp. 6989-6997
    • Wang, Q.1    Nagarkar, D.R.2    Bowman, E.R.3    Schneider, D.4    Gosangi, B.5
  • 37
    • 84855954760 scopus 로고    scopus 로고
    • The toll-like receptor 3-mediated antiviral response is important for protection against poliovirus infection in poliovirus receptor transgenic mice
    • Abe Y, Fujii K, Nagata N, Takeuchi O, Akira S, et al. (2012) The toll-like receptor 3-mediated antiviral response is important for protection against poliovirus infection in poliovirus receptor transgenic mice. J Virol 86: 185-194.
    • (2012) J Virol , vol.86 , pp. 185-194
    • Abe, Y.1    Fujii, K.2    Nagata, N.3    Takeuchi, O.4    Akira, S.5
  • 38
    • 33644752821 scopus 로고    scopus 로고
    • West Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and -independent pathways without antagonizing host defense signaling
    • Fredericksen BL, Gale M Jr, (2006) West Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and-independent pathways without antagonizing host defense signaling. J Virol 80: 2913-2923.
    • (2006) J Virol , vol.80 , pp. 2913-2923
    • Fredericksen, B.L.1    Gale Jr., M.2
  • 39
    • 70350625078 scopus 로고    scopus 로고
    • Cleavage of IPS-1 in cells infected with human rhinovirus
    • Drahos J, Racaniello VR, (2009) Cleavage of IPS-1 in cells infected with human rhinovirus. J Virol 83: 11581-11587.
    • (2009) J Virol , vol.83 , pp. 11581-11587
    • Drahos, J.1    Racaniello, V.R.2
  • 41
    • 79953279338 scopus 로고    scopus 로고
    • The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling
    • Mukherjee A, Morosky SA, Delorme-Axford E, Dybdahl-Sissoko N, Oberste MS, et al. (2011) The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling. PLoS Pathog 7: e1001311.
    • (2011) PLoS Pathog , vol.7
    • Mukherjee, A.1    Morosky, S.A.2    Delorme-Axford, E.3    Dybdahl-Sissoko, N.4    Oberste, M.S.5
  • 42
    • 77955006559 scopus 로고    scopus 로고
    • The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses
    • Lei X, Liu X, Ma Y, Sun Z, Yang Y, et al. (2010) The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses. J Virol 84: 8051-8061.
    • (2010) J Virol , vol.84 , pp. 8051-8061
    • Lei, X.1    Liu, X.2    Ma, Y.3    Sun, Z.4    Yang, Y.5
  • 43
    • 78149413053 scopus 로고    scopus 로고
    • Influenza A virus strains that circulate in humans differ in the ability of their NS1 proteins to block the activation of IRF3 and interferon-beta transcription
    • Kuo RL, Zhao C, Malur M, Krug RM, (2010) Influenza A virus strains that circulate in humans differ in the ability of their NS1 proteins to block the activation of IRF3 and interferon-beta transcription. Virology 408: 146-158.
    • (2010) Virology , vol.408 , pp. 146-158
    • Kuo, R.L.1    Zhao, C.2    Malur, M.3    Krug, R.M.4
  • 44
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 45
    • 80052278508 scopus 로고    scopus 로고
    • Cleavage of the adaptor protein TRIF by enterovirus 71 3C inhibits antiviral responses mediated by Toll-like receptor 3
    • Lei X, Sun Z, Liu X, Jin Q, He B, et al. (2011) Cleavage of the adaptor protein TRIF by enterovirus 71 3C inhibits antiviral responses mediated by Toll-like receptor 3. J Virol 85: 8811-8818.
    • (2011) J Virol , vol.85 , pp. 8811-8818
    • Lei, X.1    Sun, Z.2    Liu, X.3    Jin, Q.4    He, B.5
  • 46
    • 84863172614 scopus 로고    scopus 로고
    • Melanoma differentiation-associated gene 5 is critical for protection against Theiler's virus-induced demyelinating disease
    • Jin YH, Kim SJ, So EY, Meng L, Colonna M, et al. (2012) Melanoma differentiation-associated gene 5 is critical for protection against Theiler's virus-induced demyelinating disease. J Virol 86: 1531-1543.
    • (2012) J Virol , vol.86 , pp. 1531-1543
    • Jin, Y.H.1    Kim, S.J.2    So, E.Y.3    Meng, L.4    Colonna, M.5
  • 47
    • 3242704988 scopus 로고    scopus 로고
    • A mouse-adapted enterovirus 71 strain causes neurological disease in mice after oral infection
    • Wang YF, Chou CT, Lei HY, Liu CC, Wang SM, et al. (2004) A mouse-adapted enterovirus 71 strain causes neurological disease in mice after oral infection. J Virol 78: 7916-7924.
    • (2004) J Virol , vol.78 , pp. 7916-7924
    • Wang, Y.F.1    Chou, C.T.2    Lei, H.Y.3    Liu, C.C.4    Wang, S.M.5
  • 48
    • 34248168157 scopus 로고    scopus 로고
    • Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses
    • Venkataraman T, Valdes M, Elsby R, Kakuta S, Caceres G, et al. (2007) Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses. J Immunol 178: 6444-6455.
    • (2007) J Immunol , vol.178 , pp. 6444-6455
    • Venkataraman, T.1    Valdes, M.2    Elsby, R.3    Kakuta, S.4    Caceres, G.5
  • 49
    • 67649413594 scopus 로고    scopus 로고
    • The RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNA
    • Li X, Ranjith-Kumar CT, Brooks MT, Dharmaiah S, Herr AB, et al. (2009) The RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNA. J Biol Chem 284: 13881-13891.
    • (2009) J Biol Chem , vol.284 , pp. 13881-13891
    • Li, X.1    Ranjith-Kumar, C.T.2    Brooks, M.T.3    Dharmaiah, S.4    Herr, A.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.