Oxygen-independent regulation of HIF-1: Novel involvement of PI3K/ AKT/mTOR pathway in cancer

Current Cancer Drug Targets

Volumn 13, Issue 3, 2013, Pages 245-251

  Agani, Faton ^a   Jiang, Bing Hua ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

AKT; Growth factors; HIF 1; Hypoxia; MAPK; Oncogenes; PI3K; Tumor suppressors

Indexed keywords

ALVESPIMYCIN; DIGOXIN; DOXORUBICIN; FIRTECAN; HYPOXIA INDUCIBLE FACTOR 1; IRINOTECAN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; RECEPTOR FOR ACTIVATED C KINASE 1; S6 KINASE; SOMATOMEDIN C; TANESPIMYCIN; TOPOTECAN; UBIQUITIN PROTEIN LIGASE E3; VASCULOTROPIN; VON HIPPEL LINDAU PROTEIN;

ANGIOGENESIS; ARTICLE; CELL PROLIFERATION; CELL PROTECTION; HUMAN; HYPOXIA; NEOPLASM; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RNA TRANSLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR GROWTH; UPREGULATION;

ANTINEOPLASTIC AGENTS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; MOLECULAR TARGETED THERAPY; NEOPLASM PROTEINS; NEOPLASMS; ONCOGENE PROTEIN PP60(V-SRC); PHOSPHATIDYLINOSITOL 3-KINASE; PROTEIN STABILITY; PROTEIN SUBUNITS; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84876880959     PISSN: 15680096     EISSN: 18735576     Source Type: Journal    
DOI: 10.2174/1568009611313030003     Document Type: Article

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