-
1
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid, and other disease
-
Folkman, J. Angiogenesis in cancer, vascular, rheumatoid, and other disease. Nat. Med., 1: 27-31, 1995.
-
(1995)
Nat. Med.
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
2
-
-
0030935836
-
Tumor angiogenesis and prognosis
-
Fox, S. B. Tumor angiogenesis and prognosis. Histopathology, 30: 294-301, 1997.
-
(1997)
Histopathology
, vol.30
, pp. 294-301
-
-
Fox, S.B.1
-
3
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet, P., Ferreira, V., Breier, G., Pollefeyt, S., Kieckens, L., Gertsenstein, M., Fahrig, M., Vandenhoeck, A., Harpal, K., Eberhardt, C., Declercq, C., Pawling, J., Moons, L., Collen, D., Risau, W., and Nagy, A. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature (Lond.), 380: 435-439, 1996.
-
(1996)
Nature (Lond.)
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
Fahrig, M.7
Vandenhoeck, A.8
Harpal, K.9
Eberhardt, C.10
Declercq, C.11
Pawling, J.12
Moons, L.13
Collen, D.14
Risau, W.15
Nagy, A.16
-
4
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
Ferrara, N., Carver-Moore, K., Chen, H., Dowd, M., Lu, L., O'Shea, K. S., Powell Braxton, L., Hillan, K. J., and Moore, M. W. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature (Lond.), 380: 439-442, 1996.
-
(1996)
Nature (Lond.)
, vol.380
, pp. 439-442
-
-
Ferrara, N.1
Carver-Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O'Shea, K.S.6
Powell Braxton, L.7
Hillan, K.J.8
Moore, M.W.9
-
5
-
-
0029816983
-
Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: Novel concepts of angiostatic therapy from intravital video microscopy
-
Borgstrom, P., Killan, K. J., Sriramarao, P., and Ferrara, N. Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: novel concepts of angiostatic therapy from intravital video microscopy. Cancer Res., 56: 4032-4039, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 4032-4039
-
-
Borgstrom, P.1
Killan, K.J.2
Sriramarao, P.3
Ferrara, N.4
-
6
-
-
0029782859
-
Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor
-
Cheng, S-Y., Huang, H-J. S., Nagane, M., Ji, X-D., Wang, D., Shih, C. C-Y., Arap, W., Huang, C-M., and Cavenee, W. K. Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc. Natl. Acad. Sci. USA, 93: 8502-8507, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8502-8507
-
-
Cheng, S.-Y.1
Huang, H.-J.S.2
Nagane, M.3
Ji, X.-D.4
Wang, D.5
Shih, C.C.-Y.6
Arap, W.7
Huang, C.-M.8
Cavenee, W.K.9
-
7
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo
-
Kim, K. J., Li, B., Winer, J., Armanini, M., Gillett, N., Phillips, H. S., and Ferrara, N. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo. Nature (Lond.), 362: 841-844, 1993.
-
(1993)
Nature (Lond.)
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
Phillips, H.S.6
Ferrara, N.7
-
8
-
-
0030029271
-
Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence
-
Saleh, M., Stacker, S. A., and Wilks, A. F. Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence. Cancer Res., 56: 393-401, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 393-401
-
-
Saleh, M.1
Stacker, S.A.2
Wilks, A.F.3
-
9
-
-
0028935608
-
Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
-
Warren, R. S., Yuan, H., Matli, M. R., Gillett, N. A., and Ferrara, N. Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J. Clin. Invest., 95: 1789-1797, 1995.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 1789-1797
-
-
Warren, R.S.1
Yuan, H.2
Matli, M.R.3
Gillett, N.A.4
Ferrara, N.5
-
10
-
-
0029949160
-
Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by anti-vascular endothelial growth factor/vascular permeability factor antibody
-
Yuan, F., Chen, Y., Dellian, M., Safabakhsh, N., Ferrara, N., and Jain, R. K. Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by anti-vascular endothelial growth factor/vascular permeability factor antibody. Proc. Natl. Acad. Sci. USA, 93: 14765-14770, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14765-14770
-
-
Yuan, F.1
Chen, Y.2
Dellian, M.3
Safabakhsh, N.4
Ferrara, N.5
Jain, R.K.6
-
11
-
-
0027432324
-
Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis
-
Plate, K. H., Breier, G., Millauer, B., Ullrich, A., and Risau, W. Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis. Cancer Res., 53: 5822-5827, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 5822-5827
-
-
Plate, K.H.1
Breier, G.2
Millauer, B.3
Ullrich, A.4
Risau, W.5
-
12
-
-
0026446102
-
Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo
-
Plate, K. H., Breier, G., Weich, H. A., and Risau, W. Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature (Lond.), 359: 845-848, 1992.
-
(1992)
Nature (Lond.)
, vol.359
, pp. 845-848
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
Risau, W.4
-
13
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki, D., Itin, A., Soffer, D., and Keshet, E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature (Lond.), 359: 843-845, 1992.
-
(1992)
Nature (Lond.)
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
14
-
-
0028870050
-
Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
-
Shweiki, D., Neeman, M., Itin, A., and Keshet, E. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis. Proc. Natl. Acad. Sci. USA, 92: 768-772, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 768-772
-
-
Shweiki, D.1
Neeman, M.2
Itin, A.3
Keshet, E.4
-
15
-
-
0030614893
-
2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
-
2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nat. Med., 3: 177-182, 1997.
-
(1997)
Nat. Med.
, vol.3
, pp. 177-182
-
-
Helmlinger, G.1
Yuan, F.2
Dellian, M.3
Jain, R.K.4
-
16
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
-
Vaupel, P., Kallinowski, F., and Okunieff, P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res., 49: 6449-6465, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
17
-
-
0021345887
-
Coordinate regulation of glycolysis by hypoxia in mammalian cells
-
Robin, E. D., Murphy, B. J., and Theodore, J. Coordinate regulation of glycolysis by hypoxia in mammalian cells. J. Cell. Physiol., 118: 287-290, 1984.
-
(1984)
J. Cell. Physiol.
, vol.118
, pp. 287-290
-
-
Robin, E.D.1
Murphy, B.J.2
Theodore, J.3
-
18
-
-
0025215947
-
Coordinate reciprocal trends in glycolytic and mitochondrial transcript accumulations during the in vitro differentiation of human myoblasts
-
Webster, K. A., Gunning, P., Hardeman, E., Wallace, D. C., and Kedes, L. Coordinate reciprocal trends in glycolytic and mitochondrial transcript accumulations during the in vitro differentiation of human myoblasts. J. Cell. Physiol., 142: 566-573, 1990.
-
(1990)
J. Cell. Physiol.
, vol.142
, pp. 566-573
-
-
Webster, K.A.1
Gunning, P.2
Hardeman, E.3
Wallace, D.C.4
Kedes, L.5
-
19
-
-
0030023026
-
Wide expression of the human erythrocyte glucose transporter Glut1 in human cancers
-
Younes, M., Lechago, L. V., Somoano, J. R., Mosharaf, M., and Lechago, J. Wide expression of the human erythrocyte glucose transporter Glut1 in human cancers. Cancer Res., 56: 1164-1167, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 1164-1167
-
-
Younes, M.1
Lechago, L.V.2
Somoano, J.R.3
Mosharaf, M.4
Lechago, J.5
-
20
-
-
11444255268
-
On respiratory impairment in cancer cells
-
Washington DC
-
Warburg, O. On respiratory impairment in cancer cells. Science (Washington DC), 124: 269-270, 1956.
-
(1956)
Science
, vol.124
, pp. 269-270
-
-
Warburg, O.1
-
21
-
-
0030460724
-
Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxiainducible factor 1
-
Semenza, G. L., Jiang, B-H., Leung, S. W., Passantino, R., Concordet, J-P., Maire, P., and Giallongo, A. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxiainducible factor 1. J. Biol. Chem., 271: 32529-32537, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32529-32537
-
-
Semenza, G.L.1
Jiang, B.-H.2
Leung, S.W.3
Passantino, R.4
Concordet, J.-P.5
Maire, P.6
Giallongo, A.7
-
22
-
-
0028068606
-
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
-
Semenza, G. L., Roth, P. H., Fang, H-M., and Wang, G. L. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J. Biol. Chem., 269: 23757-23763, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23757-23763
-
-
Semenza, G.L.1
Roth, P.H.2
Fang, H.-M.3
Wang, G.L.4
-
23
-
-
0029775242
-
Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
-
Hockel, M., Schlenger, K., Aral, B., Mitze, M., Schaffer, U., and Vaupel, P. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res., 56: 4509-4515, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 4509-4515
-
-
Hockel, M.1
Schlenger, K.2
Aral, B.3
Mitze, M.4
Schaffer, U.5
Vaupel, P.6
-
24
-
-
0030022252
-
Tumor oxygenation predicts the likelihood of distant metastases in human soft tissue sarcoma
-
Brizel, D. M., Scully, S. P., Harrelson, J. M., Layfield, L. J., Bean, J. M., Prosnitz, L. R., and Dewhirst, M. W. Tumor oxygenation predicts the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res., 56: 941-943, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 941-943
-
-
Brizel, D.M.1
Scully, S.P.2
Harrelson, J.M.3
Layfield, L.J.4
Bean, J.M.5
Prosnitz, L.R.6
Dewhirst, M.W.7
-
25
-
-
0028784650
-
Correlation of high lactate levels in human cervical cancer with incidence of metastasis
-
Schwickert, G., Walenta, S., Sundfor, K., Rofstad, E. K., and Mueller-Klieser, W. Correlation of high lactate levels in human cervical cancer with incidence of metastasis. Cancer Res., 55: 4757-4759, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4757-4759
-
-
Schwickert, G.1
Walenta, S.2
Sundfor, K.3
Rofstad, E.K.4
Mueller-Klieser, W.5
-
26
-
-
0029117223
-
Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
-
Ikeda, E., Achen, M. G., Breier, G., and Risau, W. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J. Biol. Chem., 270: 19761-19766, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19761-19766
-
-
Ikeda, E.1
Achen, M.G.2
Breier, G.3
Risau, W.4
-
27
-
-
0029039195
-
Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
-
Levy, A. P., Levy, N. S., Wegner, S., and Goldberg, M. A. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J. Biol. Chem., 270: 13333-13340, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13333-13340
-
-
Levy, A.P.1
Levy, N.S.2
Wegner, S.3
Goldberg, M.A.4
-
28
-
-
0023405817
-
Regulation of glycolytic enzyme RNA transcriptional rates by oxygen availability in skeletal muscle cells
-
Webster, K. A. Regulation of glycolytic enzyme RNA transcriptional rates by oxygen availability in skeletal muscle cells. Mol. Cell. Biochem., 77: 19-28, 1987.
-
(1987)
Mol. Cell. Biochem.
, vol.77
, pp. 19-28
-
-
Webster, K.A.1
-
29
-
-
0028805375
-
Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct cis-acting sequences
-
Ebert, B. L., Firth, J. D., and Ratcliffe, P. J. Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct cis-acting sequences. J. Biol. Chem., 270: 29083-29089, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29083-29089
-
-
Ebert, B.L.1
Firth, J.D.2
Ratcliffe, P.J.3
-
30
-
-
0028359320
-
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: Similarities with the erythropoietin 3′ enhancer
-
Firth, J. D., Ebert, B. L., Pugh, C. W., and Ratcliffe, P. J. Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3′ enhancer. Proc. Natl. Acad. Sci. USA, 91: 6496-6500, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6496-6500
-
-
Firth, J.D.1
Ebert, B.L.2
Pugh, C.W.3
Ratcliffe, P.J.4
-
31
-
-
0029101515
-
Hypoxic regulation of lactate dehydrogenase A: Interaction between hypoxia-inducible factor 1 and cAMP response elements
-
Firth, J. D., Ebert, B. L., and Ratcliffe, P. J. Hypoxic regulation of lactate dehydrogenase A: interaction between hypoxia-inducible factor 1 and cAMP response elements. J. Biol. Chem., 270: 21021-21027, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21021-21027
-
-
Firth, J.D.1
Ebert, B.L.2
Ratcliffe, P.J.3
-
32
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe, J. A., Jiang, B-H., Iyer, N. V., Agani, N., Leung, S. W., Koos, R. D., and Semenza, G. L. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell. Biol., 16: 4604-4613, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.-H.2
Iyer, N.V.3
Agani, N.4
Leung, S.W.5
Koos, R.D.6
Semenza, G.L.7
-
33
-
-
0029788974
-
Induction of phosphoglycerate kinase 1 gene expression by hypoxia: Roles of ARNT and HIF-1α
-
Li, H., Ko, H. P., and Whitlock, J. P., Jr. Induction of phosphoglycerate kinase 1 gene expression by hypoxia: roles of ARNT and HIF-1α. J. Biol. Chem., 271: 21262-21267, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21262-21267
-
-
Li, H.1
Ko, H.P.2
Whitlock Jr., J.P.3
-
34
-
-
0030588298
-
Absolute requirement of aryl hydrocarbon receptor nuclear translocator protein for gene activation by hypoxia
-
Salceda, S., Beck, I., and Caro, J. Absolute requirement of aryl hydrocarbon receptor nuclear translocator protein for gene activation by hypoxia. Arch. Biochem. Biophys., 334: 389-394, 1996.
-
(1996)
Arch. Biochem. Biophys.
, vol.334
, pp. 389-394
-
-
Salceda, S.1
Beck, I.2
Caro, J.3
-
35
-
-
0029888061
-
The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression: Studies in ARNT-deficient cells
-
Wood, S. M., Gleadle, J. M., Pugh, C. W., Hankinson, O., and Ratcliffe, P. J. The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression: studies in ARNT-deficient cells. J. Biol. Chem., 271: 15117-15123, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15117-15123
-
-
Wood, S.M.1
Gleadle, J.M.2
Pugh, C.W.3
Hankinson, O.4
Ratcliffe, P.J.5
-
37
-
-
0025906014
-
Cloning of a factor required for activity of the Ah (dioxin) receptor
-
Washington DC
-
Hoffman, E. C., Reyes, H., Chu, F-F., Sander, F., Conley, L. H., Brooks, B. A., and Hankinson, O. Cloning of a factor required for activity of the Ah (dioxin) receptor. Science (Washington DC), 252: 954-958, 1991.
-
(1991)
Science
, vol.252
, pp. 954-958
-
-
Hoffman, E.C.1
Reyes, H.2
Chu, F.-F.3
Sander, F.4
Conley, L.H.5
Brooks, B.A.6
Hankinson, O.7
-
39
-
-
0027210562
-
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia
-
Wang, G. L., and Semenza, G. L. General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc. Natl. Acad. Sci. USA, 90: 4304-4308, 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4304-4308
-
-
Wang, G.L.1
Semenza, G.L.2
-
40
-
-
0029982422
-
Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor 1α
-
Wenger, R. H., Rolfs, A., Marti, H. H., Guenet, J-L., and Gassmann, M. Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor 1α. Biochem. Biophys. Res. Commun., 223: 54-59, 1996.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.223
, pp. 54-59
-
-
Wenger, R.H.1
Rolfs, A.2
Marti, H.H.3
Guenet, J.-L.4
Gassmann, M.5
-
41
-
-
0030583293
-
In vivo expression of mRNAs encoding hypoxia-inducible factor 1
-
Wiener, C. M., Booth, G., and Semenza, G. L. In vivo expression of mRNAs encoding hypoxia-inducible factor 1. Biochem. Biophys. Res. Commun., 225: 485-488, 1996.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 485-488
-
-
Wiener, C.M.1
Booth, G.2
Semenza, G.L.3
-
42
-
-
0029753008
-
Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit
-
Huang, L. E., Arany, Z., Livingston, D. M., and Bunn, H. F. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit. J. Biol. Chem., 271: 32253-32259, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
43
-
-
0029944965
-
Dimerization, DNA-binding, and transactivation properties of hypoxia-inducible factor 1
-
Jiang, B-H., Rue, E., Wang, G. L., Roe, R., and Semenza, G. L. Dimerization, DNA-binding, and transactivation properties of hypoxia-inducible factor 1. J. Biol. Chem., 271: 17771-17778, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17771-17778
-
-
Jiang, B.-H.1
Rue, E.2
Wang, G.L.3
Roe, R.4
Semenza, G.L.5
-
44
-
-
0030787469
-
Transactivation and inhibitory domains of hypoxia-inducible factor 1α: Modulation of transcriptional activity by oxygen tension
-
Jiang, B-H., Zheng, J. Z., Leung, S. W., Roe, R., and Semenza, G. L. Transactivation and inhibitory domains of hypoxia-inducible factor 1α: modulation of transcriptional activity by oxygen tension. J. Biol. Chem., 272: 19253-19260, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19253-19260
-
-
Jiang, B.-H.1
Zheng, J.Z.2
Leung, S.W.3
Roe, R.4
Semenza, G.L.5
-
45
-
-
0030968939
-
Targeting gene expression to hypoxic tumor cells
-
Dachs, G. U., Patterson, A. V., Firth, J. D., Ratcliffe, P. J., Townsend, K. M. S., Stratford, I. J., and Harris, A. L. Targeting gene expression to hypoxic tumor cells. Nat. Med., 3: 515-520, 1997.
-
(1997)
Nat. Med.
, vol.3
, pp. 515-520
-
-
Dachs, G.U.1
Patterson, A.V.2
Firth, J.D.3
Ratcliffe, P.J.4
Townsend, K.M.S.5
Stratford, I.J.6
Harris, A.L.7
-
46
-
-
0029068339
-
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
-
Mukhopadhyay, D., Tsiokas, L., Zhou, X-M., Foster, D., Brugge, J. S., and Sukhatme, V. P. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature (Lond.), 375: 577-581, 1995.
-
(1995)
Nature (Lond.)
, vol.375
, pp. 577-581
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Zhou, X.-M.3
Foster, D.4
Brugge, J.S.5
Sukhatme, V.P.6
-
47
-
-
0028865988
-
Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression
-
Mukhopadhyay, D., Tsiokas, L., and Sukhatme, V. P. Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression. Cancer Res., 55: 6161-6165, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 6161-6165
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Sukhatme, V.P.3
-
48
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza, G. L., and Wang, G. L. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol. Cell. Biol., 12: 5447-5454, 1992.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
49
-
-
0028816847
-
Purification and characterization of hypoxia-inducible factor 1
-
Wang, G. L., and Semenza, G. L. Purification and characterization of hypoxia-inducible factor 1. J. Biol. Chem., 270: 1230-1237, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 1230-1237
-
-
Wang, G.L.1
Semenza, G.L.2
-
50
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski, P., and Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162: 156-159, 1987.
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
51
-
-
0004136246
-
-
Cold Spring Harbor, NY: Cold Spring Harbor Laboratory
-
Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual, 2nd Ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
-
(1989)
Molecular Cloning: A Laboratory Manual, 2nd Ed.
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
52
-
-
0026607928
-
Cloning and characterization of a thermolabile v-src gene for use in reversible transformation of mammalian cells
-
Maroney, A. C., Qureshi, S. A., Foster, D. A., and Brugge, J. S. Cloning and characterization of a thermolabile v-src gene for use in reversible transformation of mammalian cells. Oncogene, 7: 1207-1214, 1992.
-
(1992)
Oncogene
, vol.7
, pp. 1207-1214
-
-
Maroney, A.C.1
Qureshi, S.A.2
Foster, D.A.3
Brugge, J.S.4
-
53
-
-
0025968796
-
Intracellular leucine zipper interactions suggest c-myc hetero-oligomerization
-
Dang, C. V., Barrett, J., Villa-Garcia, M., Resar, L. M. S., Kato, G. J., and Fearon, E. R. Intracellular leucine zipper interactions suggest c-myc hetero-oligomerization. Mol. Cell. Biol., 11: 954-962, 1991.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 954-962
-
-
Dang, C.V.1
Barrett, J.2
Villa-Garcia, M.3
Resar, L.M.S.4
Kato, G.J.5
Fearon, E.R.6
-
54
-
-
0027943988
-
2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity
-
2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes Dev., 8: 2527-2539, 1994.
-
(1994)
Genes Dev.
, vol.8
, pp. 2527-2539
-
-
Sun, P.1
Enslen, H.2
Myung, P.S.3
Maurer, R.A.4
-
55
-
-
0026023289
-
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
-
Soriano, P., Montgomery, C., Geske, R., and Bradley, A. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell, 64: 693-702, 1991.
-
(1991)
Cell
, vol.64
, pp. 693-702
-
-
Soriano, P.1
Montgomery, C.2
Geske, R.3
Bradley, A.4
-
56
-
-
0031016301
-
Induction of hypoxia-inducible factor 1, erythropoietin, vascular endothelial growth factor, and glucose transporter-1 by hypoxia: Evidence against a regulatory role for Src kinase
-
Gleadle, J. M., and Ratcliffe, P. J. Induction of hypoxia-inducible factor 1, erythropoietin, vascular endothelial growth factor, and glucose transporter-1 by hypoxia: evidence against a regulatory role for Src kinase. Blood, 89: 503-509, 1997.
-
(1997)
Blood
, vol.89
, pp. 503-509
-
-
Gleadle, J.M.1
Ratcliffe, P.J.2
-
57
-
-
14444271278
-
Repression of MAP kinases ERK1/ERK2 activity by a protein tyrosine phosphatase in rat fibroblasts transformed by upstream oncoproteins
-
in press
-
Gopalbhai, K., and Meloche, S. Repression of MAP kinases ERK1/ERK2 activity by a protein tyrosine phosphatase in rat fibroblasts transformed by upstream oncoproteins. J. Cell. Physiol., in press, 1997.
-
(1997)
J. Cell. Physiol.
-
-
Gopalbhai, K.1
Meloche, S.2
-
58
-
-
0030044039
-
Post-transcriptional regulation of vascular endothelial growth factor by hypoxia
-
Levy, A. P., Levy, N. S., and Goldberg, M. A. Post-transcriptional regulation of vascular endothelial growth factor by hypoxia. J. Biol. Chem., 271: 2746-2753, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2746-2753
-
-
Levy, A.P.1
Levy, N.S.2
Goldberg, M.A.3
-
59
-
-
0029082384
-
Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes
-
Stein, I., Neeman, M., Shweiki, D., Itin, A., and Keshet, E. Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes. Mol. Cell. Biol., 15: 5363-5368, 1995.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5363-5368
-
-
Stein, I.1
Neeman, M.2
Shweiki, D.3
Itin, A.4
Keshet, E.5
-
60
-
-
0028785860
-
Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1
-
Wang, G. L., Jiang, B-H., and Semenza, G. L. Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1. Biochem. Biophys. Res. Commun., 216: 669-675, 1995.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.216
, pp. 669-675
-
-
Wang, G.L.1
Jiang, B.-H.2
Semenza, G.L.3
-
61
-
-
0018119549
-
Reversion of transformed glycolysis to normal by inhibition of protein synthesis in rat kidney cells infected with temperature-sensitive mutant of Rous sarcoma virus
-
Carroll, R. C., Ash, J. F., Vogt, P. K., and Singer, S. J. Reversion of transformed glycolysis to normal by inhibition of protein synthesis in rat kidney cells infected with temperature-sensitive mutant of Rous sarcoma virus. Proc. Natl. Acad. Sci. USA, 75: 5015-5019, 1978.
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, pp. 5015-5019
-
-
Carroll, R.C.1
Ash, J.F.2
Vogt, P.K.3
Singer, S.J.4
-
62
-
-
0005162157
-
Alterations in glucose metabolism in chick-embryo cells transformed by Rous sarcoma virus: Intracellular levels of glycolytic intermediates
-
Singh, V. N., Singh, M., August, J. T., and Horecker, B. L. Alterations in glucose metabolism in chick-embryo cells transformed by Rous sarcoma virus: intracellular levels of glycolytic intermediates. Proc. Natl. Acad. Sci. USA, 71: 4129-4132, 1974.
-
(1974)
Proc. Natl. Acad. Sci. USA
, vol.71
, pp. 4129-4132
-
-
Singh, V.N.1
Singh, M.2
August, J.T.3
Horecker, B.L.4
-
63
-
-
0014320511
-
Glycolysis in chick embryo cell cultures transformed by Rous sarcoma virus
-
Steck, T. L., Kaufman, S., and Bader, J. P. Glycolysis in chick embryo cell cultures transformed by Rous sarcoma virus. Cancer Res., 28: 1611-1619, 1968.
-
(1968)
Cancer Res.
, vol.28
, pp. 1611-1619
-
-
Steck, T.L.1
Kaufman, S.2
Bader, J.P.3
-
64
-
-
0030921103
-
c-Myc transactivation of LDH-A: Implications for tumor metabolism and growth
-
Shim, H., Dolde, C., Lewis, B. C., Wu, C-S., Dang, G., Jungmann, R. A., Dalla-Favera, R., and Dang, C. V. c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. Proc. Natl. Acad. Sci. USA, 94: 6658-6663, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6658-6663
-
-
Shim, H.1
Dolde, C.2
Lewis, B.C.3
Wu, C.-S.4
Dang, G.5
Jungmann, R.A.6
Dalla-Favera, R.7
Dang, C.V.8
-
65
-
-
0029681850
-
Oncogenic transformation and hypoxia synergistically act to modulate vascular endothelial growth factor expression
-
Mazure, N. M., Chen, E. Y., Yen, P., Laderoute, K. R., and Giaccia, A. J. Oncogenic transformation and hypoxia synergistically act to modulate vascular endothelial growth factor expression. Cancer Res., 56: 3436-3440, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 3436-3440
-
-
Mazure, N.M.1
Chen, E.Y.2
Yen, P.3
Laderoute, K.R.4
Giaccia, A.J.5
-
66
-
-
12644317846
-
Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways
-
Arbiser, J. L., Moses, M. A., Fernandez, C. A., Ghiso, N., Cao, Y., Klauber, N., Frank, D., Brownlee, M., Flynn, E., Parangi, S., Byers, H. R., and Folkman, J. Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways. Proc. Natl. Acad. Sci. USA, 94: 861-866, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 861-866
-
-
Arbiser, J.L.1
Moses, M.A.2
Fernandez, C.A.3
Ghiso, N.4
Cao, Y.5
Klauber, N.6
Frank, D.7
Brownlee, M.8
Flynn, E.9
Parangi, S.10
Byers, H.R.11
Folkman, J.12
-
67
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumors
-
Graeber, T. G., Osmanian, C., Jacks, T., Housman, D. E., Koch, C. J., Lowe, S. W., and Giaccia, A. J. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumors. Nature (Lond.), 379: 88-91, 1996.
-
(1996)
Nature (Lond.)
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
Housman, D.E.4
Koch, C.J.5
Lowe, S.W.6
Giaccia, A.J.7
-
68
-
-
0029891049
-
Glucose catabolism in cancer cells: Amplification of the gene encoding type II hexokinase
-
Rempel, A., Mathupala, S. P., Griffin, C. A., Hawkins, A. L., and Pedersen, P. L. Glucose catabolism in cancer cells: amplification of the gene encoding type II hexokinase. Cancer Res., 56: 2468-2471, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 2468-2471
-
-
Rempel, A.1
Mathupala, S.P.2
Griffin, C.A.3
Hawkins, A.L.4
Pedersen, P.L.5
-
69
-
-
0029785838
-
Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene
-
Gnarra, J. R., Zhou, S., Merrill, M. J., Wagner, J. R., Krumm, A., Papavassiliou, E., Oldfield, E. H., Klausner, R. D., and Linehan, W. M. Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene. Proc. Natl. Acad. Sci. USA, 93: 10589-10594, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10589-10594
-
-
Gnarra, J.R.1
Zhou, S.2
Merrill, M.J.3
Wagner, J.R.4
Krumm, A.5
Papavassiliou, E.6
Oldfield, E.H.7
Klausner, R.D.8
Linehan, W.M.9
-
70
-
-
0029785321
-
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein
-
Iliopoulos, O., Levy, A. P., Jiang, C., Kaelin, W. G., Jr., and Goldberg, M. A. Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein. Proc. Natl. Acad. Sci. USA, 93: 10595-10599, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10595-10599
-
-
Iliopoulos, O.1
Levy, A.P.2
Jiang, C.3
Kaelin Jr., W.G.4
Goldberg, M.A.5
-
71
-
-
0030200804
-
Transcriptional regulation by hypoxia-inducible factor 1: Molecular mechanisms of oxygen homeostasis
-
Semenza, G. L. Transcriptional regulation by hypoxia-inducible factor 1: molecular mechanisms of oxygen homeostasis. Trends Cardiovasc. Med., 6: 151-157, 1996.
-
(1996)
Trends Cardiovasc. Med.
, vol.6
, pp. 151-157
-
-
Semenza, G.L.1
|