GRP78 overproduction in pancreatic beta cells protects against high-fat-diet-induced diabetes in mice

Diabetologia

Volumn 56, Issue 5, 2013, Pages 1057-1067

  Teodoro Morrison, T ^a,b   Schuiki, I ^a   Zhang, L ^a   Belsham, D D ^b   Volchuk, A ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Endoplasmic reticulum stress; Obesity; Pancreatic beta cell; Type 2 diabetes

Indexed keywords

GLUCOSE REGULATED PROTEIN 78; GLUCOSE TRANSPORTER 2; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENDOPLASMIC RETICULUM STRESS; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; HYPERINSULINEMIA; INSULIN RESISTANCE; LIPID DIET; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; CROSSES, GENETIC; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; ENDOPLASMIC RETICULUM STRESS; GLUCOSE TRANSPORTER TYPE 2; HEAT-SHOCK PROTEINS; HYPERINSULINISM; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OBESITY; PROMOTER REGIONS, GENETIC; RATS; SURFACE PROPERTIES; TISSUE CULTURE TECHNIQUES; UP-REGULATION;

EID: 84876496860     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-2855-7     Document Type: Article

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