메뉴 건너뛰기




Volumn 193, Issue 3, 2013, Pages 751-770

Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE EPSILON; DNA DIRECTED DNA POLYMERASE GAMMA; DOUBLE STRANDED DNA; EXONUCLEASE;

EID: 84876442276     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.112.146910     Document Type: Article
Times cited : (43)

References (146)
  • 1
    • 78649701177 scopus 로고    scopus 로고
    • Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase epsilon
    • Aksenova, A., K. Volkov, J. Maceluch, Z. F. Pursell, I. B. Rogozin et al., 2010 Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase epsilon. PLoS Genet. 6: e1001209.
    • (2010) PLoS Genet , vol.6
    • Aksenova, A.1    Volkov, K.2    Maceluch, J.3    Pursell, Z.F.4    Rogozin, I.B.5
  • 2
    • 33645006224 scopus 로고    scopus 로고
    • DNA replication fidelity: Proofreading in trans
    • Albertson, T. M., and B. D. Preston, 2006 DNA replication fidelity: proofreading in trans. Curr. Biol. 16: R209-R211.
    • (2006) Curr. Biol , vol.16
    • Albertson, T.M.1    Preston, B.D.2
  • 3
    • 70350126567 scopus 로고    scopus 로고
    • DNA polymerase e and d proofreading suppress discrete mutator and cancer phenotypes in mice
    • Albertson, T. M., M. Ogawa, J. M. Bugni, L. E. Hays, Y. Chen et al., 2009 DNA polymerase e and d proofreading suppress discrete mutator and cancer phenotypes in mice. Proc. Natl. Acad. Sci. USA 106: 17101-17104.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 17101-17104
    • Albertson, T.M.1    Ogawa, M.2    Bugni, J.M.3    Hays, L.E.4    Chen, Y.5
  • 4
    • 0027943565 scopus 로고
    • Specific cleavage of model recombination and repair intermediates by the yeast Rad1-Rad10 DNA endonuclease
    • Bardwell, A. J., L. Bardwell, A. E. Tomkinson, and E. C. Friedberg, 1994 Specific cleavage of model recombination and repair intermediates by the yeast Rad1-Rad10 DNA endonuclease. Science 265: 2082-2085.
    • (1994) Science , vol.265 , pp. 2082-2085
    • Bardwell, A.J.1    Bardwell, L.2    Tomkinson, A.E.3    Friedberg, E.C.4
  • 5
    • 0037965787 scopus 로고    scopus 로고
    • The mechanism of Mus81-Mms4 cleavage site selection distinguishes it from the homologous endonuclease Rad1- Rad10
    • Bastin-Shanower, S. A., W. M. Fricke, J. R. Mullen, and S. J. Brill, 2003 The mechanism of Mus81-Mms4 cleavage site selection distinguishes it from the homologous endonuclease Rad1- Rad10. Mol. Cell. Biol. 23: 3487-3496.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 3487-3496
    • Bastin-Shanower, S.A.1    Fricke, W.M.2    Mullen, J.R.3    Brill, S.J.4
  • 6
    • 0028857175 scopus 로고
    • Analyzing fidelity of DNA polymerases
    • Bebenek, K., and T. A. Kunkel, 1995 Analyzing fidelity of DNA polymerases. Methods Enzymol. 262: 217-232.
    • (1995) Methods Enzymol , vol.262 , pp. 217-232
    • Bebenek, K.1    Kunkel, T.A.2
  • 7
    • 0024474078 scopus 로고
    • A conserved 39/59 exonuclease active site in prokaryotic and eukaryotic DNA polymerases
    • Bernad, A., L. Blanco, J. M. Lazaro, G. Martin, and M. Salas, 1989 A conserved 39/59 exonuclease active site in prokaryotic and eukaryotic DNA polymerases. Cell 59: 219-228.
    • (1989) Cell , vol.59 , pp. 219-228
    • Bernad, A.1    Blanco, L.2    Lazaro, J.M.3    Martin, G.4    Salas, M.5
  • 8
    • 79251589920 scopus 로고    scopus 로고
    • Discovery of mutations in Saccharomyces cerevisiae by pooled linkage analysis and whole-genome sequencing
    • Birkeland, S. R., N. Jin, A. C. Ozdemir, R. H. Lyons Jr, L. S. Weisman et al., 2010 Discovery of mutations in Saccharomyces cerevisiae by pooled linkage analysis and whole-genome sequencing. Genetics 186: 1127-1137.
    • (2010) Genetics , vol.186 , pp. 1127-1137
    • Birkeland, S.R.1    Jin, N.2    Ozdemir, A.C.3    Lyons Jr., R.H.4    Weisman, L.S.5
  • 9
    • 0035900652 scopus 로고    scopus 로고
    • Mus81-Eme1 are essential components of a Holliday junction resolvase
    • Boddy, M. N., P. H. Gaillard, W. H. McDonald, P. Shanahan, J. R. Yates III. et al. 2001 Mus81-Eme1 are essential components of a Holliday junction resolvase. Cell 107: 537-548.
    • (2001) Cell , vol.107 , pp. 537-548
    • Boddy, M.N.1    Gaillard, P.H.2    McDonald, W.H.3    Shanahan, P.4    Yates III, J.R.5
  • 10
    • 0021668558 scopus 로고
    • A positive selection for mutants lacking orotidine-59-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance
    • Boeke, J. D., F. LaCroute, and G. R. Fink, 1984 A positive selection for mutants lacking orotidine-59-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol. Gen. Genet. 197: 345-346.
    • (1984) Mol. Gen. Genet , vol.197 , pp. 345-346
    • Boeke, J.D.1    Lacroute, F.2    Fink, G.R.3
  • 11
    • 0032579440 scopus 로고    scopus 로고
    • Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCRmediated gene disruption and other applications
    • Brachmann, C. B., A. Davies, G. J. Cost, E. Caputo, J. Li et al., 1998 Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCRmediated gene disruption and other applications. Yeast 14: 115-132.
    • (1998) Yeast , vol.14 , pp. 115-132
    • Brachmann, C.B.1    Davies, A.2    Cost, G.J.3    Caputo, E.4    Li, J.5
  • 12
    • 28244472115 scopus 로고    scopus 로고
    • Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair
    • Cannavo, E., G. Marra, J. Sabates-Bellver, M. Menigatti, S. M. Lipkin et al., 2005 Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair. Cancer Res. 65: 10759-10766.
    • (2005) Cancer Res , vol.65 , pp. 10759-10766
    • Cannavo, E.1    Marra, G.2    Sabates-Bellver, J.3    Menigatti, M.4    Lipkin, S.M.5
  • 13
    • 0021032993 scopus 로고
    • Competition between high and low mutating strains of Escherichia coli
    • Chao, L., and E. C. Cox, 1983 Competition between high and low mutating strains of Escherichia coli. Evolution 37: 125-134.
    • (1983) Evolution , vol.37 , pp. 125-134
    • Chao, L.1    Cox, E.C.2
  • 14
    • 25444462730 scopus 로고    scopus 로고
    • Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse
    • Chen, P. C., S. Dudley, W. Hagen, D. Dizon, L. Paxton et al., 2005 Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse. Cancer Res. 65: 8662-8670.
    • (2005) Cancer Res , vol.65 , pp. 8662-8670
    • Chen, P.C.1    Dudley, S.2    Hagen, W.3    Dizon, D.4    Paxton, L.5
  • 15
    • 18244405819 scopus 로고    scopus 로고
    • Human Mus81-associated endonuclease cleaves Holliday junctions in vitro
    • Chen, X. B., R. Melchionna, C. M. Denis, P. H. Gaillard, A. Blasina et al., 2001 Human Mus81-associated endonuclease cleaves Holliday junctions in vitro. Mol. Cell 8: 1117-1127.
    • (2001) Mol. Cell , vol.8 , pp. 1117-1127
    • Chen, X.B.1    Melchionna, R.2    Denis, C.M.3    Gaillard, P.H.4    Blasina, A.5
  • 16
    • 0018800392 scopus 로고
    • Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms
    • Clayton, L. K., M. F. Goodman, E. W. Branscomb, and D. J. Galas, 1979 Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms. J. Biol. Chem. 254: 1902-1912.
    • (1979) J. Biol. Chem , vol.254 , pp. 1902-1912
    • Clayton, L.K.1    Goodman, M.F.2    Branscomb, E.W.3    Galas, D.J.4
  • 17
    • 0033636253 scopus 로고    scopus 로고
    • Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants
    • Datta, A., J. L. Schmeits, N. S. Amin, P. J. Lau, K. Myung et al., 2000 Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants. Mol. Cell 6: 593-603.
    • (2000) Mol. Cell , vol.6 , pp. 593-603
    • Datta, A.1    Schmeits, J.L.2    Amin, N.S.3    Lau, P.J.4    Myung, K.5
  • 18
    • 33847256353 scopus 로고    scopus 로고
    • The speed of evolution and maintenance of variation in asexual populations
    • Desai, M. M., D. S. Fisher, and A. W. Murray, 2007 The speed of evolution and maintenance of variation in asexual populations. Curr. Biol. 17: 385-394.
    • (2007) Curr. Biol , vol.17 , pp. 385-394
    • Desai, M.M.1    Fisher, D.S.2    Murray, A.W.3
  • 19
    • 0025963376 scopus 로고
    • Kinetic partitioning between the exonuclease and polymerase sites in DNA error correction
    • Donlin, M. J., S. S. Patel, and K. A. Johnson, 1991 Kinetic partitioning between the exonuclease and polymerase sites in DNA error correction. Biochemistry 30: 538-546.
    • (1991) Biochemistry , vol.30 , pp. 538-546
    • Donlin, M.J.1    Patel, S.S.2    Johnson, K.A.3
  • 20
    • 0027471149 scopus 로고
    • General antimutators are improbable
    • Drake, J. W., 1993 General antimutators are improbable. J. Mol. Biol. 229: 8-13.
    • (1993) J. Mol. Biol , vol.229 , pp. 8-13
    • Drake, J.W.1
  • 22
    • 0033529497 scopus 로고    scopus 로고
    • Analysis of the essential functions of the C-terminal protein/protein interaction domain of Saccharomyces cerevisiae Pol e and its unexpected ability to support growth in the absence of the DNA polymerase domain
    • Dua, R., D. L. Levy, and J. L. Campbell, 1999 Analysis of the essential functions of the C-terminal protein/protein interaction domain of Saccharomyces cerevisiae Pol e and its unexpected ability to support growth in the absence of the DNA polymerase domain. J. Biol. Chem. 274: 22283-22288.
    • (1999) J. Biol. Chem , vol.274 , pp. 22283-22288
    • Dua, R.1    Levy, D.L.2    Campbell, J.L.3
  • 23
    • 84865589857 scopus 로고    scopus 로고
    • Two flavors of bulk segregant analysis in yeast
    • Dunham, M. J., 2012 Two flavors of bulk segregant analysis in yeast. Methods Mol. Biol. 871: 41-54.
    • (2012) Methods Mol. Biol , vol.871 , pp. 41-54
    • Dunham, M.J.1
  • 24
    • 0038441327 scopus 로고    scopus 로고
    • Evolution experiments with microorganisms: The dynamics and genetic bases of adaptation
    • Elena, S. F., and R. E. Lenski, 2003 Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation. Nat. Rev. Genet. 4: 457-469.
    • (2003) Nat. Rev. Genet , vol.4 , pp. 457-469
    • Elena, S.F.1    Lenski, R.E.2
  • 25
    • 1942453396 scopus 로고    scopus 로고
    • Mutation accumulation in populations of varying size: The distribution of mutational effects for fitness correlates in Caenorhabditis elegans
    • Estes, S., P. C. Phillips, D. R. Denver, W. K. Thomas, and M. Lynch, 2004 Mutation accumulation in populations of varying size: the distribution of mutational effects for fitness correlates in Caenorhabditis elegans. Genetics 166: 1269-1279.
    • (2004) Genetics , vol.166 , pp. 1269-1279
    • Estes, S.1    Phillips, P.C.2    Denver, D.R.3    Thomas, W.K.4    Lynch, M.5
  • 26
    • 0034955240 scopus 로고    scopus 로고
    • Schizosaccharomyces pombe cells lacking the amino-terminal catalytic domains of DNA polymerase epsilon are viable but require the DNA damage checkpoint control
    • Feng, W., and G. D'Urso, 2001 Schizosaccharomyces pombe cells lacking the amino-terminal catalytic domains of DNA polymerase epsilon are viable but require the DNA damage checkpoint control. Mol. Cell. Biol. 21: 4495-4504.
    • (2001) Mol. Cell. Biol , vol.21 , pp. 4495-4504
    • Feng, W.1    D'Urso, G.2
  • 27
    • 0028842855 scopus 로고
    • Effects of Escherichia coli dnaE antimutator alleles in a proofreading-deficient mutD5 strain
    • Fijalkowska, I. J., and R. M. Schaaper, 1995 Effects of Escherichia coli dnaE antimutator alleles in a proofreading-deficient mutD5 strain. J. Bacteriol. 177: 5979-5986.
    • (1995) J. Bacteriol , vol.177 , pp. 5979-5986
    • Fijalkowska, I.J.1    Schaaper, R.M.2
  • 28
    • 0027169584 scopus 로고
    • Mutants of Escherichia coli with increased fidelity of DNA replication
    • Fijalkowska, I. J., R. L. Dunn, and R. M. Schaaper, 1993 Mutants of Escherichia coli with increased fidelity of DNA replication. Genetics 134: 1023-1030.
    • (1993) Genetics , vol.134 , pp. 1023-1030
    • Fijalkowska, I.J.1    Dunn, R.L.2    Schaaper, R.M.3
  • 29
    • 0032514709 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations
    • Flores-Rozas, H., and R. D. Kolodner, 1998 The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. Proc. Natl. Acad. Sci. USA 95: 12404-12409.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12404-12409
    • Flores-Rozas, H.1    Kolodner, R.D.2
  • 30
    • 23844522523 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae DNA polymerase d: High fidelity for base substitutions but lower fidelity for singleand multi-base deletions
    • Fortune, J. M., Y. I. Pavlov, C. M. Welch, E. Johansson, P. M. Burgers et al., 2005 Saccharomyces cerevisiae DNA polymerase d: high fidelity for base substitutions but lower fidelity for singleand multi-base deletions. J. Biol. Chem. 280: 29980-29987.
    • (2005) J. Biol. Chem , vol.280 , pp. 29980-29987
    • Fortune, J.M.1    Pavlov, Y.I.2    Welch, C.M.3    Johansson, E.4    Burgers, P.M.5
  • 31
    • 67449152488 scopus 로고    scopus 로고
    • Cancer genome sequencing: An interim analysis
    • Fox, E. J., J. J. Salk, and L. A. Loeb, 2009 Cancer genome sequencing: an interim analysis. Cancer Res. 69: 4948-4950.
    • (2009) Cancer Res , vol.69 , pp. 4948-4950
    • Fox, E.J.1    Salk, J.J.2    Loeb, L.A.3
  • 33
    • 0034049514 scopus 로고    scopus 로고
    • The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitness
    • Funchain, P., A. Yeung, J. L. Stewart, R. Lin, M. M. Slupska et al., 2000 The consequences of growth of a mutator strain of Escherichia coli as measured by loss of function among multiple gene targets and loss of fitness. Genetics 154: 959-970.
    • (2000) Genetics , vol.154 , pp. 959-970
    • Funchain, P.1    Yeung, A.2    Stewart, J.L.3    Lin, R.4    Slupska, M.M.5
  • 34
    • 8644285427 scopus 로고    scopus 로고
    • Idling by DNA polymerase d maintains a ligatable nick during lagging-strand DNA replication
    • Garg, P., C. M. Stith, N. Sabouri, E. Johansson, and P. M. Burgers, 2004 Idling by DNA polymerase d maintains a ligatable nick during lagging-strand DNA replication. Genes Dev. 18: 2764-2773.
    • (2004) Genes Dev , vol.18 , pp. 2764-2773
    • Garg, P.1    Stith, C.M.2    Sabouri, N.3    Johansson, E.4    Burgers, P.M.5
  • 36
    • 0035970874 scopus 로고    scopus 로고
    • Costs and benefits of high mutation rates: Adaptive evolution of bacteria in the mouse gut
    • Giraud, A., I. Matic, O. Tenaillon, A. Clara, M. Radman et al., 2001a Costs and benefits of high mutation rates: adaptive evolution of bacteria in the mouse gut. Science 291: 2606-2608.
    • (2001) Science , vol.291 , pp. 2606-2608
    • Giraud, A.1    Matic, I.2    Tenaillon, O.3    Clara, A.4    Radman, M.5
  • 38
    • 0037180555 scopus 로고    scopus 로고
    • High incidence of epithelial cancers in mice deficient for DNA polymerase d proofreading
    • Goldsby, R. E., L. E. Hays, X. Chen, E. A. Olmsted, W. B. Slayton et al., 2002 High incidence of epithelial cancers in mice deficient for DNA polymerase d proofreading. Proc. Natl. Acad. Sci. USA 99: 15560-15565.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 15560-15565
    • Goldsby, R.E.1    Hays, L.E.2    Chen, X.3    Olmsted, E.A.4    Slayton, W.B.5
  • 39
    • 0030953472 scopus 로고    scopus 로고
    • Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins
    • Greene, C. N., and S. Jinks-Robertson, 1997 Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins. Mol. Cell. Biol. 17: 2844-2850.
    • (1997) Mol. Cell. Biol , vol.17 , pp. 2844-2850
    • Greene, C.N.1    Jinks-Robertson, S.2
  • 40
    • 0034809479 scopus 로고    scopus 로고
    • Spontaneous frameshift mutations in Saccharomyces cerevisiae: Accumulation during DNA replication and removal by proofreading and mismatch repair activities
    • Greene, C. N., and S. Jinks-Robertson, 2001 Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities. Genetics 159: 65-75.
    • (2001) Genetics , vol.159 , pp. 65-75
    • Greene, C.N.1    Jinks-Robertson, S.2
  • 41
    • 0029994841 scopus 로고    scopus 로고
    • A new efficient gene disruption cassette for repeated use in budding yeast
    • Guldener, U., S. Heck, T. Fielder, J. Beinhauer, and J. H. Hegemann, 1996 A new efficient gene disruption cassette for repeated use in budding yeast. Nucleic Acids Res. 24: 2519-2524.
    • (1996) Nucleic Acids Res , vol.24 , pp. 2519-2524
    • Guldener, U.1    Heck, S.2    Fielder, T.3    Beinhauer, J.4    Hegemann, J.H.5
  • 42
    • 0035394142 scopus 로고    scopus 로고
    • Translesion synthesis by yeast DNA polymerase z from templates containing lesions of ultraviolet radiation and acetylaminofluorene
    • Guo, D., X. Wu, D. K. Rajpal, J. S. Taylor, and Z. Wang, 2001 Translesion synthesis by yeast DNA polymerase z from templates containing lesions of ultraviolet radiation and acetylaminofluorene. Nucleic Acids Res. 29: 2875-2883.
    • (2001) Nucleic Acids Res , vol.29 , pp. 2875-2883
    • Guo, D.1    Wu, X.2    Rajpal, D.K.3    Taylor, J.S.4    Wang, Z.5
  • 43
    • 0032540309 scopus 로고    scopus 로고
    • ATPdependent assembly of a ternary complex consisting of a DNA mismatch and the yeast MSH2-MSH6 and MLH1-PMS1 protein complexes
    • Habraken, Y., P. Sung, L. Prakash, and S. Prakash, 1998 ATPdependent assembly of a ternary complex consisting of a DNA mismatch and the yeast MSH2-MSH6 and MLH1-PMS1 protein complexes. J. Biol. Chem. 273: 9837-9841.
    • (1998) J. Biol. Chem , vol.273 , pp. 9837-9841
    • Habraken, Y.1    Sung, P.2    Prakash, L.3    Prakash, S.4
  • 44
    • 66349117823 scopus 로고    scopus 로고
    • Fluctuation AnaLysis CalculatOR: A web tool for the determination of mutation rate using Luria-Delbrück fluctuation analysis
    • Hall, B. M., C. X. Ma, P. Liang, and K. K. Singh, 2009 Fluctuation AnaLysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbrück fluctuation analysis. Bioinformatics 25: 1564-1565.
    • (2009) Bioinformatics , vol.25 , pp. 1564-1565
    • Hall, B.M.1    Ma, C.X.2    Liang, P.3    Singh, K.K.4
  • 45
    • 0035871360 scopus 로고    scopus 로고
    • Roles of yeast DNA polymerases d and z and of Rev1 in the bypass of abasic sites
    • Haracska, L., I. Unk, R. E. Johnson, E. Johansson, P. M. Burgers et al., 2001 Roles of yeast DNA polymerases d and z and of Rev1 in the bypass of abasic sites. Genes Dev. 15: 945-954.
    • (2001) Genes Dev , vol.15 , pp. 945-954
    • Haracska, L.1    Unk, I.2    Johnson, R.E.3    Johansson, E.4    Burgers, P.M.5
  • 46
    • 0034628618 scopus 로고    scopus 로고
    • Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast
    • Harfe, B. D., B. K. Minesinger, and S. Jinks-Robertson, 2000 Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr. Biol. 10: 145-148.
    • (2000) Curr. Biol , vol.10 , pp. 145-148
    • Harfe, B.D.1    Minesinger, B.K.2    Jinks-Robertson, S.3
  • 47
    • 34548761416 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs
    • Harrington, J. M., and R. D. Kolodner, 2007 Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs. Mol. Cell. Biol. 27: 6546-6554.
    • (2007) Mol. Cell. Biol , vol.27 , pp. 6546-6554
    • Harrington, J.M.1    Kolodner, R.D.2
  • 48
    • 80055094218 scopus 로고    scopus 로고
    • Mutator suppression and escape from replication error-induced extinction in yeast
    • Herr, A. J., M. Ogawa, N. A. Lawrence, L. N. Williams, J. M. Eggington et al., 2011a Mutator suppression and escape from replication error-induced extinction in yeast. PLoS Genet. 7: e1002282.
    • (2011) PLoS Genet , vol.7
    • Herr, A.J.1    Ogawa, M.2    Lawrence, N.A.3    Williams, L.N.4    Eggington, J.M.5
  • 50
    • 81855189485 scopus 로고    scopus 로고
    • Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates
    • Hombauer, H., C. S. Campbell, C. E. Smith, A. Desai, and R. D. Kolodner, 2011 Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates. Cell 147: 1040-1053.
    • (2011) Cell , vol.147 , pp. 1040-1053
    • Hombauer, H.1    Campbell, C.S.2    Smith, C.E.3    Desai, A.4    Kolodner, R.D.5
  • 51
    • 45449103427 scopus 로고    scopus 로고
    • DNA mismatch repair: Molecular mechanism, cancer, and ageing
    • Hsieh, P., and K. Yamane, 2008 DNA mismatch repair: molecular mechanism, cancer, and ageing. Mech. Ageing Dev. 129: 391-407.
    • (2008) Mech. Ageing Dev , vol.129 , pp. 391-407
    • Hsieh, P.1    Yamane, K.2
  • 53
  • 54
    • 77949570420 scopus 로고    scopus 로고
    • The kinetic and chemical mechanism of high-fidelity DNA polymerases
    • Johnson, K. A., 2010 The kinetic and chemical mechanism of high-fidelity DNA polymerases. Biochim. Biophys. Acta 1804: 1041-1048.
    • (2010) Biochim. Biophys. Acta , vol.1804 , pp. 1041-1048
    • Johnson, K.A.1
  • 55
    • 0029870366 scopus 로고    scopus 로고
    • Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stability
    • Johnson, R. E., G. K. Kovvali, L. Prakash, and S. Prakash, 1996 Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stability. J. Biol. Chem. 271: 7285-7288.
    • (1996) J. Biol. Chem , vol.271 , pp. 7285-7288
    • Johnson, R.E.1    Kovvali, G.K.2    Prakash, L.3    Prakash, S.4
  • 56
    • 0034738983 scopus 로고    scopus 로고
    • Eukaryotic polymerases i and z act sequentially to bypass DNA lesions
    • Johnson, R. E., M. T. Washington, L. Haracska, S. Prakash, and L. Prakash, 2000 Eukaryotic polymerases i and z act sequentially to bypass DNA lesions. Nature 406: 1015-1019.
    • (2000) Nature , vol.406 , pp. 1015-1019
    • Johnson, R.E.1    Washington, M.T.2    Haracska, L.3    Prakash, S.4    Prakash, L.5
  • 57
    • 0037388383 scopus 로고    scopus 로고
    • Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
    • Johnson, S. J., J. S. Taylor, and L. S. Beese, 2003 Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations. Proc. Natl. Acad. Sci. USA 100: 3895-3900.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 3895-3900
    • Johnson, S.J.1    Taylor, J.S.2    Beese, L.S.3
  • 58
    • 8544278025 scopus 로고    scopus 로고
    • DNA polymerase fidelity: Kinetics, structure, and checkpoints
    • Joyce, C. M., and S. J. Benkovic, 2004 DNA polymerase fidelity: kinetics, structure, and checkpoints. Biochemistry 43: 14317-14324.
    • (2004) Biochemistry , vol.43 , pp. 14317-14324
    • Joyce, C.M.1    Benkovic, S.J.2
  • 59
    • 33746189409 scopus 로고    scopus 로고
    • Endonucleolytic function of MutLa in human mismatch repair
    • Kadyrov, F. A., L. Dzantiev, N. Constantin, and P. Modrich, 2006 Endonucleolytic function of MutLa in human mismatch repair. Cell 126: 297-308.
    • (2006) Cell , vol.126 , pp. 297-308
    • Kadyrov, F.A.1    Dzantiev, L.2    Constantin, N.3    Modrich, P.4
  • 61
    • 0037224965 scopus 로고    scopus 로고
    • Checkpoint activation regulates mutagenic translesion synthesis
    • Kai, M., and T. S. Wang, 2003 Checkpoint activation regulates mutagenic translesion synthesis. Genes Dev. 17: 64-76.
    • (2003) Genes Dev , vol.17 , pp. 64-76
    • Kai, M.1    Wang, T.S.2
  • 63
    • 0034595502 scopus 로고    scopus 로고
    • Evidence from mutational specificity studies that yeast DNA polymerases d and e replicate different DNA strands at an intracellular replication fork
    • Karthikeyan, R., E. J. Vonarx, A. F. Straffon, M. Simon, G. Faye et al., 2000 Evidence from mutational specificity studies that yeast DNA polymerases d and e replicate different DNA strands at an intracellular replication fork. J. Mol. Biol. 299: 405-419.
    • (2000) J. Mol. Biol , vol.299 , pp. 405-419
    • Karthikeyan, R.1    Vonarx, E.J.2    Straffon, A.F.3    Simon, M.4    Faye, G.5
  • 64
    • 0032587610 scopus 로고    scopus 로고
    • DNA polymerase e catalytic domains are dispensable for DNA replication, DNA repair, and cell viability
    • Kesti, T., K. Flick, S. Keranen, J. E. Syväoja, and C. Wittenberg, 1999 DNA polymerase e catalytic domains are dispensable for DNA replication, DNA repair, and cell viability. Mol. Cell 3: 679-685.
    • (1999) Mol. Cell , vol.3 , pp. 679-685
    • Kesti, T.1    Flick, K.2    Keranen, S.3    Syväoja, J.E.4    Wittenberg, C.5
  • 67
    • 54249092768 scopus 로고    scopus 로고
    • Dividing the workload at a eukaryotic replication fork
    • Kunkel, T. A., and P. M. Burgers, 2008 Dividing the workload at a eukaryotic replication fork. Trends Cell Biol. 18: 521-527.
    • (2008) Trends Cell Biol , vol.18 , pp. 521-527
    • Kunkel, T.A.1    Burgers, P.M.2
  • 68
    • 0028277915 scopus 로고
    • Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit
    • Kunkel, T. A., S. S. Patel, and K. A. Johnson, 1994 Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit. Proc. Natl. Acad. Sci. USA 91: 6830-6834.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6830-6834
    • Kunkel, T.A.1    Patel, S.S.2    Johnson, K.A.3
  • 70
    • 22144436659 scopus 로고    scopus 로고
    • Sensitivity to phosphonoacetic acid: A new phenotype to probe DNA polymerase d in Saccharomyces cerevisiae
    • Li, L., K. M. Murphy, U. Kanevets, and L. J. Reha-Krantz, 2005 Sensitivity to phosphonoacetic acid: a new phenotype to probe DNA polymerase d in Saccharomyces cerevisiae. Genetics 170: 569-580.
    • (2005) Genetics , vol.170 , pp. 569-580
    • Li, L.1    Murphy, K.M.2    Kanevets, U.3    Reha-Krantz, L.J.4
  • 71
    • 79957501125 scopus 로고    scopus 로고
    • Human cancers express mutator phenotypes: Origin, consequences and targeting
    • Loeb, L. A., 2011 Human cancers express mutator phenotypes: origin, consequences and targeting. Nat. Rev. Cancer 11: 450-457.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 450-457
    • Loeb, L.A.1
  • 72
    • 0016176530 scopus 로고
    • Errors in DNA replication as a basis of malignant changes
    • Loeb, L. A., C. F. Springgate, and N. Battula, 1974 Errors in DNA replication as a basis of malignant changes. Cancer Res. 34: 2311-2321.
    • (1974) Cancer Res , vol.34 , pp. 2311-2321
    • Loeb, L.A.1    Springgate, C.F.2    Battula, N.3
  • 73
    • 45549102966 scopus 로고    scopus 로고
    • Cancers exhibit a mutator phenotype: Clinical implications
    • Loeb, L. A., J. H. Bielas, and R. A. Beckman, 2008 Cancers exhibit a mutator phenotype: clinical implications. Cancer Res. 68: 3551-3557.
    • (2008) Cancer Res , vol.68 , pp. 3551-3557
    • Loeb, L.A.1    Bielas, J.H.2    Beckman, R.A.3
  • 74
    • 34249660610 scopus 로고    scopus 로고
    • Highly tolerated amino acid substitutions increase the fidelity of Escherichia coli DNA polymerase I
    • Loh, E., J. Choe, and L. A. Loeb, 2007 Highly tolerated amino acid substitutions increase the fidelity of Escherichia coli DNA polymerase I. J. Biol. Chem. 282: 12201-12209.
    • (2007) J. Biol. Chem , vol.282 , pp. 12201-12209
    • Loh, E.1    Choe, J.2    Loeb, L.A.3
  • 75
    • 0031023159 scopus 로고    scopus 로고
    • Proliferation of mutators in a cell population
    • Mao, E. F., L. Lane, J. Lee, and J. H. Miller, 1997 Proliferation of mutators in a cell population. J. Bacteriol. 179: 417-422.
    • (1997) J. Bacteriol , vol.179 , pp. 417-422
    • Mao, E.F.1    Lane, L.2    Lee, J.3    Miller, J.H.4
  • 76
    • 0029868110 scopus 로고    scopus 로고
    • Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair
    • Marsischky, G. T., N. Filosi, M. F. Kane, and R. Kolodner, 1996 Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes Dev. 10: 407-420.
    • (1996) Genes Dev , vol.10 , pp. 407-420
    • Marsischky, G.T.1    Filosi, N.2    Kane, M.F.3    Kolodner, R.4
  • 77
    • 38049125552 scopus 로고    scopus 로고
    • The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases
    • McCulloch, S. D., and T. A. Kunkel, 2008 The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Res. 18: 148-161.
    • (2008) Cell Res , vol.18 , pp. 148-161
    • McCulloch, S.D.1    Kunkel, T.A.2
  • 78
    • 33644836197 scopus 로고    scopus 로고
    • iMARS-mutation analysis reporting software: An analysis of spontaneous cII mutation spectra
    • Morgan, C., and P. D. Lewis, 2006 iMARS-mutation analysis reporting software: an analysis of spontaneous cII mutation spectra. Mutat. Res. 603: 15-26.
    • (2006) Mutat. Res , vol.603 , pp. 15-26
    • Morgan, C.1    Lewis, P.D.2
  • 79
    • 0028174896 scopus 로고
    • The 39/59 exonucleases of both DNA polymerases d and e participate in correcting errors of DNA replication in Saccharomyces cerevisiae
    • Morrison, A., and A. Sugino, 1994 The 39/59 exonucleases of both DNA polymerases d and e participate in correcting errors of DNA replication in Saccharomyces cerevisiae. Mol. Gen. Genet. 242: 289-296.
    • (1994) Mol. Gen. Genet , vol.242 , pp. 289-296
    • Morrison, A.1    Sugino, A.2
  • 80
    • 0026004621 scopus 로고
    • Eukaryotic DNA polymerase amino acid sequence required for 39 / 59 exonuclease activity
    • Morrison, A., J. B. Bell, T. A. Kunkel, and A. Sugino, 1991 Eukaryotic DNA polymerase amino acid sequence required for 39 / 59 exonuclease activity. Proc. Natl. Acad. Sci. USA 88: 9473-9477.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9473-9477
    • Morrison, A.1    Bell, J.B.2    Kunkel, T.A.3    Sugino, A.4
  • 81
    • 0027417017 scopus 로고
    • Pathway correcting DNA replication errors in Saccharomyces cerevisiae
    • Morrison, A., A. L. Johnson, L. H. Johnston, and A. Sugino, 1993 Pathway correcting DNA replication errors in Saccharomyces cerevisiae. EMBO J. 12: 1467-1473.
    • (1993) EMBO J , vol.12 , pp. 1467-1473
    • Morrison, A.1    Johnson, A.L.2    Johnston, L.H.3    Sugino, A.4
  • 82
    • 0027245585 scopus 로고
    • The yeast gene MSH3 defines a new class of eukaryotic MutS homologues
    • New, L., K. Liu, and G. F. Crouse, 1993 The yeast gene MSH3 defines a new class of eukaryotic MutS homologues. Mol. Gen. Genet. 239: 97-108.
    • (1993) Mol. Gen. Genet , vol.239 , pp. 97-108
    • New, L.1    Liu, K.2    Crouse, G.F.3
  • 83
    • 33646390723 scopus 로고    scopus 로고
    • Evidence for extrinsic exonucleolytic proofreading
    • Nick McElhinny, S. A., Y. I. Pavlov, and T. A. Kunkel, 2006 Evidence for extrinsic exonucleolytic proofreading. Cell Cycle 5: 958-962.
    • (2006) Cell Cycle , vol.5 , pp. 958-962
    • Nick, M.S.A.1    Pavlov, Y.I.2    Kunkel, T.A.3
  • 85
    • 10844266565 scopus 로고    scopus 로고
    • Experimental adaptation of Salmonella typhimurium to mice
    • Nilsson, A. I., E. Kugelberg, O. G. Berg, and D. I. Andersson, 2004 Experimental adaptation of Salmonella typhimurium to mice. Genetics 168: 1119-1130.
    • (2004) Genetics , vol.168 , pp. 1119-1130
    • Nilsson, A.I.1    Kugelberg, E.2    Berg, O.G.3    Andersson, D.I.4
  • 86
    • 49849087552 scopus 로고    scopus 로고
    • A mutation in the putative MLH3 endonuclease domain confers a defect in both mismatch repair and meiosis in Saccharomyces cerevisiae
    • Nishant, K. T., A. J. Plys, and E. Alani, 2008 A mutation in the putative MLH3 endonuclease domain confers a defect in both mismatch repair and meiosis in Saccharomyces cerevisiae. Genetics 179: 747-755.
    • (2008) Genetics , vol.179 , pp. 747-755
    • Nishant, K.T.1    Plys, A.J.2    Alani, E.3
  • 88
    • 74249092035 scopus 로고    scopus 로고
    • Participation of DNA polymerase z in replication of undamaged DNA in Saccharomyces cerevisiae
    • Northam, M. R., H. A. Robinson, O. V. Kochenova, and P. V. Shcherbakova, 2010 Participation of DNA polymerase z in replication of undamaged DNA in Saccharomyces cerevisiae. Genetics 184: 27-42.
    • (2010) Genetics , vol.184 , pp. 27-42
    • Northam, M.R.1    Robinson, H.A.2    Kochenova, O.V.3    Shcherbakova, P.V.4
  • 89
    • 0036860714 scopus 로고    scopus 로고
    • Enrichment and elimination of mutY mutators in Escherichia coli populations
    • Notley-McRobb, L., S. Seeto, and T. Ferenci, 2002 Enrichment and elimination of mutY mutators in Escherichia coli populations. Genetics 162: 1055-1062.
    • (2002) Genetics , vol.162 , pp. 1055-1062
    • Notley-McRobb, L.1    Seeto, S.2    Ferenci, T.3
  • 90
    • 0029659046 scopus 로고    scopus 로고
    • hMutSb, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
    • Palombo, F., I. Iaccarino, E. Nakajima, M. Ikejima, T. Shimada et al., 1996 hMutSb, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. Curr. Biol. 6: 1181-1184.
    • (1996) Curr. Biol , vol.6 , pp. 1181-1184
    • Palombo, F.1    Iaccarino, I.2    Nakajima, E.3    Ikejima, M.4    Shimada, T.5
  • 91
    • 75749086797 scopus 로고    scopus 로고
    • DNA polymerases at the eukaryotic fork-20 years later
    • Pavlov, Y. I., and P. V. Shcherbakova, 2010 DNA polymerases at the eukaryotic fork-20 years later. Mutat. Res. 685: 45-53.
    • (2010) Mutat. Res , vol.685 , pp. 45-53
    • Pavlov, Y.I.1    Shcherbakova, P.V.2
  • 92
    • 0034805293 scopus 로고    scopus 로고
    • In vivo consequences of putative active site mutations in yeast DNA polymerases a, e, d, and z
    • Pavlov, Y. I., P. V. Shcherbakova, and T. A. Kunkel, 2001 In vivo consequences of putative active site mutations in yeast DNA polymerases a, e, d, and z. Genetics 159: 47-64.
    • (2001) Genetics , vol.159 , pp. 47-64
    • Pavlov, Y.I.1    Shcherbakova, P.V.2    Kunkel, T.A.3
  • 93
    • 0036345594 scopus 로고    scopus 로고
    • Yeast origins establish a strand bias for replicational mutagenesis
    • Pavlov, Y. I., C. S. Newlon, and T. A. Kunkel, 2002 Yeast origins establish a strand bias for replicational mutagenesis. Mol. Cell 10: 207-213.
    • (2002) Mol. Cell , vol.10 , pp. 207-213
    • Pavlov, Y.I.1    Newlon, C.S.2    Kunkel, T.A.3
  • 94
    • 0038371133 scopus 로고    scopus 로고
    • Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast
    • Pavlov, Y. I., I. M. Mian, and T. A. Kunkel, 2003 Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast. Curr. Biol. 13: 744-748.
    • (2003) Curr. Biol , vol.13 , pp. 744-748
    • Pavlov, Y.I.1    Mian, I.M.2    Kunkel, T.A.3
  • 95
    • 3242736410 scopus 로고    scopus 로고
    • Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations
    • Pavlov, Y. I., S. Maki, H. Maki, and T. A. Kunkel, 2004 Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. BMC Biol. 2: 11.
    • (2004) BMC Biol , vol.2 , pp. 11
    • Pavlov, Y.I.1    Maki, S.2    Maki, H.3    Kunkel, T.A.4
  • 96
    • 30944452765 scopus 로고    scopus 로고
    • Evidence that errors made by DNA polymerase α are corrected by DNA polymerase d
    • Pavlov, Y. I., C. Frahm, S. A. McElhinny, A. Niimi, M. Suzuki et al., 2006a Evidence that errors made by DNA polymerase α are corrected by DNA polymerase d. Curr. Biol. 16: 202-207.
    • (2006) Curr. Biol , vol.16 , pp. 202-207
    • Pavlov, Y.I.1    Frahm, C.2    McElhinny, S.A.3    Niimi, A.4    Suzuki, M.5
  • 97
    • 33845496081 scopus 로고    scopus 로고
    • Roles of DNA polymerases in replication, repair, and recombination in eukaryotes
    • Pavlov, Y. I., P. V. Shcherbakova, and I. B. Rogozin, 2006b Roles of DNA polymerases in replication, repair, and recombination in eukaryotes. Int. Rev. Cytol. 255: 41-132.
    • (2006) Int. Rev. Cytol , vol.255 , pp. 41-132
    • Pavlov, Y.I.1    Shcherbakova, P.V.2    Rogozin, I.B.3
  • 98
    • 24144463165 scopus 로고    scopus 로고
    • Lynch syndrome genes
    • Peltomäki, P., 2005 Lynch syndrome genes. Fam. Cancer 4: 227-232.
    • (2005) Fam. Cancer , vol.4 , pp. 227-232
    • Peltomäki, P.1
  • 100
    • 0028157956 scopus 로고
    • Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene
    • Prolla, T. A., D. M. Christie, and R. M. Liskay, 1994 Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene. Mol. Cell. Biol. 14: 407-415.
    • (1994) Mol. Cell. Biol , vol.14 , pp. 407-415
    • Prolla, T.A.1    Christie, D.M.2    Liskay, R.M.3
  • 101
    • 53249147678 scopus 로고    scopus 로고
    • DNA polymerase e: A polymerase of unusual size (and complexity)
    • Pursell, Z. F., and T. A. Kunkel, 2008 DNA polymerase e: a polymerase of unusual size (and complexity). Prog. Nucleic Acid Res. Mol. Biol. 82: 101-145.
    • (2008) Prog. Nucleic Acid Res. Mol. Biol , vol.82 , pp. 101-145
    • Pursell, Z.F.1    Kunkel, T.A.2
  • 102
    • 34447336941 scopus 로고    scopus 로고
    • Yeast DNA polymerase e participates in leading- strand DNA replication
    • Pursell, Z. F., I. Isoz, E. B. Lundstrom, E. Johansson, and T. A. Kunkel, 2007 Yeast DNA polymerase e participates in leading- strand DNA replication. Science 317: 127-130.
    • (2007) Science , vol.317 , pp. 127-130
    • Pursell, Z.F.1    Isoz, I.2    Lundstrom, E.B.3    Johansson, E.4    Kunkel, T.A.5
  • 104
    • 0026445628 scopus 로고
    • Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: Evidence for separate mitochondrial and nuclear functions
    • Reenan, R. A., and R. D. Kolodner, 1992 Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions. Genetics 132: 975-985.
    • (1992) Genetics , vol.132 , pp. 975-985
    • Reenan, R.A.1    Kolodner, R.D.2
  • 105
    • 0028915013 scopus 로고
    • Learning about DNA polymerase function by studying antimutator DNA polymerases
    • Reha-Krantz, L. J., 1995 Learning about DNA polymerase function by studying antimutator DNA polymerases. Trends Biochem. Sci. 20: 136-140.
    • (1995) Trends Biochem. Sci , vol.20 , pp. 136-140
    • Reha-Krantz, L.J.1
  • 106
    • 77949568225 scopus 로고    scopus 로고
    • DNA polymerase proofreading: Multiple roles maintain genome stability
    • Reha-Krantz, L. J., 2010 DNA polymerase proofreading: multiple roles maintain genome stability. Biochim. Biophys. Acta 1804: 1049-1063.
    • (2010) Biochim. Biophys. Acta , vol.1804 , pp. 1049-1063
    • Reha-Krantz, L.J.1
  • 107
    • 83455177210 scopus 로고    scopus 로고
    • Drug-sensitive DNA polymerase d reveals a role for mismatch repair in checkpoint activation in yeast
    • Reha-Krantz, L. J., M. S. Siddique, K. Murphy, A. Tam, M. O'Carroll et al., 2011 Drug-sensitive DNA polymerase d reveals a role for mismatch repair in checkpoint activation in yeast. Genetics 189: 1211-1224.
    • (2011) Genetics , vol.189 , pp. 1211-1224
    • Reha-Krantz, L.J.1    Siddique, M.S.2    Murphy, K.3    Tam, A.4    O'Carroll, M.5
  • 108
    • 0030067883 scopus 로고    scopus 로고
    • Suppressors of Escherichia coli mutT: Antimutators for DNA replication errors
    • Schaaper, R. M., 1996 Suppressors of Escherichia coli mutT: antimutators for DNA replication errors. Mutat. Res. 350: 17-23.
    • (1996) Mutat. Res , vol.350 , pp. 17-23
    • Schaaper, R.M.1
  • 109
    • 0031894341 scopus 로고    scopus 로고
    • Antimutator mutants in bacteriophage T4 and Escherichia coli
    • Schaaper, R. M., 1998 Antimutator mutants in bacteriophage T4 and Escherichia coli. Genetics 148: 1579-1585.
    • (1998) Genetics , vol.148 , pp. 1579-1585
    • Schaaper, R.M.1
  • 110
    • 0026550897 scopus 로고
    • An Escherichia coli dnaE mutation with suppressor activity toward mutator mutD5
    • Schaaper, R. M., and R. Cornacchio, 1992 An Escherichia coli dnaE mutation with suppressor activity toward mutator mutD5. J. Bacteriol. 174: 1974-1982.
    • (1992) J. Bacteriol , vol.174 , pp. 1974-1982
    • Schaaper, R.M.1    Cornacchio, R.2
  • 111
    • 0029908575 scopus 로고    scopus 로고
    • Base analog 6-N-hydroxylaminopurine mutagenesis in the yeast Saccharomyces cerevisiae is controlled by replicative DNA polymerases
    • Shcherbakova, P. V., V. N. Noskov, M. R. Pshenichnov, and Y. I. Pavlov, 1996 Base analog 6-N-hydroxylaminopurine mutagenesis in the yeast Saccharomyces cerevisiae is controlled by replicative DNA polymerases. Mutat. Res. 369: 33-44.
    • (1996) Mutat. Res , vol.369 , pp. 33-44
    • Shcherbakova, P.V.1    Noskov, V.N.2    Pshenichnov, M.R.3    Pavlov, Y.I.4
  • 113
    • 0036275447 scopus 로고    scopus 로고
    • Getting started with yeast
    • edited by C. Guthrie, and G. R. Fink. Academic Press, San Diego
    • Sherman, F., 2002 Getting started with yeast, pp. 3-41 in Part B: Guide to Yeast Genetics and Molecular and Cell Biology, edited by C. Guthrie, and G. R. Fink. Academic Press, San Diego.
    • (2002) Part B: Guide to Yeast Genetics and Molecular and Cell Biology , pp. 3-41
    • Sherman, F.1
  • 114
    • 0037020078 scopus 로고    scopus 로고
    • Fidelity of DNA polymerase e holoenzyme from budding yeast Saccharomyces cerevisiae
    • Shimizu, K., K. Hashimoto, J. M. Kirchner, W. Nakai, H. Nishikawa et al., 2002 Fidelity of DNA polymerase e holoenzyme from budding yeast Saccharomyces cerevisiae. J. Biol. Chem. 277: 37422-37429.
    • (2002) J. Biol. Chem , vol.277 , pp. 37422-37429
    • Shimizu, K.1    Hashimoto, K.2    Kirchner, J.M.3    Nakai, W.4    Nishikawa, H.5
  • 115
    • 0030897578 scopus 로고    scopus 로고
    • Microsatellite instability in yeast: Dependence on repeat unit size and DNA mismatch repair genes
    • Sia, E. A., R. J. Kokoska, M. Dominska, P. Greenwell, and T. D. Petes, 1997 Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes. Mol. Cell. Biol. 17: 2851-2858.
    • (1997) Mol. Cell. Biol , vol.17 , pp. 2851-2858
    • Sia, E.A.1    Kokoska, R.J.2    Dominska, M.3    Greenwell, P.4    Petes, T.D.5
  • 116
    • 0037206593 scopus 로고    scopus 로고
    • Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase z in vitro
    • Simhadri, S., P. Kramata, B. Zajc, J. M. Sayer, D. M. Jerina et al., 2002 Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase z in vitro. Mutat. Res. 508: 137-145.
    • (2002) Mutat. Res , vol.508 , pp. 137-145
    • Simhadri, S.1    Kramata, P.2    Zajc, B.3    Sayer, J.M.4    Jerina, D.M.5
  • 117
    • 0025900035 scopus 로고
    • The 39 to 59 exonuclease activity located in the DNA polymerase d subunit of Saccharomyces cerevisiae is required for accurate replication
    • Simon, M., L. Giot, and G. Faye, 1991 The 39 to 59 exonuclease activity located in the DNA polymerase d subunit of Saccharomyces cerevisiae is required for accurate replication. EMBO J. 10: 2165-2170.
    • (1991) EMBO J , vol.10 , pp. 2165-2170
    • Simon, M.1    Giot, L.2    Faye, G.3
  • 119
  • 120
    • 0030620273 scopus 로고    scopus 로고
    • Evolution of high mutation rates in experimental populations of E
    • Sniegowski, P. D., P. J. Gerrish, and R. E. Lenski, 1997 Evolution of high mutation rates in experimental populations of E. coli. Nature 387: 703-705.
    • (1997) Coli. Nature , vol.387 , pp. 703-705
    • Sniegowski, P.D.1    Gerrish, P.J.2    Lenski, R.E.3
  • 121
    • 0027306173 scopus 로고
    • Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair
    • Strand, M., T. A. Prolla, R. M. Liskay, and T. D. Petes, 1993 Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 365: 274-276.
    • (1993) Nature , vol.365 , pp. 274-276
    • Strand, M.1    Prolla, T.A.2    Liskay, R.M.3    Petes, T.D.4
  • 122
    • 79551545956 scopus 로고    scopus 로고
    • Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms
    • Stulemeijer, I. J., B. L. Pike, A. W. Faber, K. F. Verzijlbergen, T. van Welsem et al., 2011 Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms. Epigenetics Chromatin 4: 2-15.
    • (2011) Epigenetics Chromatin , vol.4 , pp. 2-15
    • Stulemeijer, I.J.1    Pike, B.L.2    Faber, A.W.3    Verzijlbergen, K.F.4    van Welsem, T.5
  • 125
    • 33747153121 scopus 로고    scopus 로고
    • Ploidy controls the success of mutators and nature of mutations during budding yeast evolution
    • Thompson, D. A., M. M. Desai, and A. W. Murray, 2006 Ploidy controls the success of mutators and nature of mutations during budding yeast evolution. Curr. Biol. 16: 1581-1590.
    • (2006) Curr. Biol , vol.16 , pp. 1581-1590
    • Thompson, D.A.1    Desai, M.M.2    Murray, A.W.3
  • 126
    • 34247575803 scopus 로고    scopus 로고
    • High-throughput strain construction and systematic synthetic lethal screening in Saccaromyces cerevisiae
    • edited by I. Stansfield, and M. J. R. Stark. Academic Press, New York
    • Tong, A. H. Y., and C. Boone, 2007 High-throughput strain construction and systematic synthetic lethal screening in Saccaromyces cerevisiae, pp. 369-386 and 706-707 in Methods in Microbiology, edited by I. Stansfield, and M. J. R. Stark. Academic Press, New York.
    • (2007) Methods In Microbiology , pp. 369-386
    • Tong, A.H.Y.1    Boone, C.2
  • 127
    • 0032588388 scopus 로고    scopus 로고
    • The 39/59 exonucleases of DNA polymerases d and e and the 59/39 exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae
    • Tran, H. T., D. A. Gordenin, and M. A. Resnick, 1999 The 39/59 exonucleases of DNA polymerases d and e and the 59/39 exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae. Mol. Cell. Biol. 19: 2000-2007.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 2000-2007
    • Tran, H.T.1    Gordenin, D.A.2    Resnick, M.A.3
  • 128
    • 0021749518 scopus 로고
    • Selection against hypermutability in Escherichia coli during long term evolution
    • Tröbner, W., and R. Piechocki, 1984 Selection against hypermutability in Escherichia coli during long term evolution. Mol. Gen. Genet. 198: 177-178.
    • (1984) Mol. Gen. Genet , vol.198 , pp. 177-178
    • Tröbner, W.1    Piechocki, R.2
  • 129
    • 0035929667 scopus 로고    scopus 로고
    • DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50_Mre11 complex
    • Trujillo, K. M., and P. Sung, 2001 DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50_Mre11 complex. J. Biol. Chem. 276: 35458-35464.
    • (2001) J. Biol. Chem , vol.276 , pp. 35458-35464
    • Trujillo, K.M.1    Sung, P.2
  • 130
    • 79958001799 scopus 로고    scopus 로고
    • Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools
    • Tsaponina, O., E. Barsoum, S. U. Astrom, and A. Chabes, 2011 Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools. PLoS Genet. 7: e1002061.
    • (2011) PLoS Genet , vol.7
    • Tsaponina, O.1    Barsoum, E.2    Astrom, S.U.3    Chabes, A.4
  • 131
    • 0034746231 scopus 로고    scopus 로고
    • Phosphodiesterase and 3 / 5 exonuclease activities of yeast Apn2 protein and requirement of these activities for repair of oxidative DNA damage
    • Unk, I., L. Haracska, S. Prakash, and L. Prakash, 2001 39- Phosphodiesterase and 3 / 5 exonuclease activities of yeast Apn2 protein and requirement of these activities for repair of oxidative DNA damage. Mol. Cell. Biol. 21: 1656-1661.
    • (2001) Mol. Cell. Biol , vol.21 , pp. 1656-1661
    • Unk, I.1    Haracska, L.2    Prakash, S.3    Prakash, L.4
  • 132
    • 0035872937 scopus 로고    scopus 로고
    • Replication slippage involves DNA polymerase pausing and dissociation
    • Viguera, E., D. Canceill, and S. D. Ehrlich, 2001 Replication slippage involves DNA polymerase pausing and dissociation. EMBO J. 20: 2587-2595.
    • (2001) EMBO J , vol.20 , pp. 2587-2595
    • Viguera, E.1    Canceill, D.2    Ehrlich, S.D.3
  • 133
    • 0031587827 scopus 로고    scopus 로고
    • Crystal structure of a pol a family replication DNA polymerase from bacteriophage RB69
    • Wang, J., A. K. Sattar, C. C. Wang, J. D. Karam, W. H. Konigsberg et al., 1997 Crystal structure of a pol a family replication DNA polymerase from bacteriophage RB69. Cell 89: 1087-1099.
    • (1997) Cell , vol.89 , pp. 1087-1099
    • Wang, J.1    Sattar, A.K.2    Wang, C.C.3    Karam, J.D.4    Konigsberg, W.H.5
  • 134
    • 0024562306 scopus 로고
    • Human DNA polymerase a: Predicted functional domains and relationships with viral DNA polymerases
    • Wang, T. S.-F., S. W. Wong, and D. Korn, 1989 Human DNA polymerase a: predicted functional domains and relationships with viral DNA polymerases. FASEB J. 3: 14-21.
    • (1989) FASEB J , vol.3 , pp. 14-21
    • Wang, T.S.-F.1    Wong, S.W.2    Korn, D.3
  • 135
    • 0032957639 scopus 로고    scopus 로고
    • Two-stage PCR protocol allowing introduction of multiple mutations, deletions and insertions using QuikChange Site-Directed Mutagenesis
    • Wang, W., and B. A. Malcolm, 1999 Two-stage PCR protocol allowing introduction of multiple mutations, deletions and insertions using QuikChange Site-Directed Mutagenesis. Biotechniques 26: 680-682.
    • (1999) Biotechniques , vol.26 , pp. 680-682
    • Wang, W.1    Malcolm, B.A.2
  • 137
    • 0036303398 scopus 로고    scopus 로고
    • Mouse models for human DNA mismatch-repair gene defects
    • Wei, K., R. Kucherlapati, and W. Edelmann, 2002 Mouse models for human DNA mismatch-repair gene defects. Trends Mol. Med. 8: 346-353.
    • (2002) Trends Mol. Med , vol.8 , pp. 346-353
    • Wei, K.1    Kucherlapati, R.2    Edelmann, W.3
  • 138
    • 77953211186 scopus 로고    scopus 로고
    • Bulk segregant analysis by high-throughput sequencing reveals a novel xylose utilization gene from Saccharomyces cerevisiae
    • Wenger, J. W., K. Schwartz, and G. Sherlock, 2010 Bulk segregant analysis by high-throughput sequencing reveals a novel xylose utilization gene from Saccharomyces cerevisiae. PLoS Genet. 6: e1000942.
    • (2010) PLoS Genet , vol.6
    • Wenger, J.W.1    Schwartz, K.2    Sherlock, G.3
  • 139
    • 0021930514 scopus 로고
    • Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2
    • Williamson, M. S., J. C. Game, and S. Fogel, 1985 Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2. Genetics 110: 609-646.
    • (1985) Genetics , vol.110 , pp. 609-646
    • Williamson, M.S.1    Game, J.C.2    Fogel, S.3
  • 140
    • 0034765995 scopus 로고    scopus 로고
    • Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiae
    • Wloch, D. M., K. Szafraniec, R. H. Borts, and R. Korona, 2001 Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiae. Genetics 159: 441-452.
    • (2001) Genetics , vol.159 , pp. 441-452
    • Wloch, D.M.1    Szafraniec, K.2    Borts, R.H.3    Korona, R.4
  • 141
    • 0036668464 scopus 로고    scopus 로고
    • Mapping of early firing origins on a replication profile of budding yeast
    • Yabuki, N., H. Terashima, and K. Kitada, 2002 Mapping of early firing origins on a replication profile of budding yeast. Genes Cells 7: 781-789.
    • (2002) Genes Cells , vol.7 , pp. 781-789
    • Yabuki, N.1    Terashima, H.2    Kitada, K.3
  • 142
    • 0033060120 scopus 로고    scopus 로고
    • Analysis of yeast pms1, msh2, and mlh1 mutators points to differences in mismatch correction efficiencies between prokaryotic and eukaryotic cells
    • Yang, Y., R. Karthikeyan, S. E. Mack, E. J. Vonarx, and B. A. Kunz, 1999 Analysis of yeast pms1, msh2, and mlh1 mutators points to differences in mismatch correction efficiencies between prokaryotic and eukaryotic cells. Mol. Gen. Genet. 261: 777-787.
    • (1999) Mol. Gen. Genet , vol.261 , pp. 777-787
    • Yang, Y.1    Karthikeyan, R.2    Mack, S.E.3    Vonarx, E.J.4    Kunz, B.A.5
  • 143
    • 33750511727 scopus 로고    scopus 로고
    • A survey of essential gene function in the yeast cell division cycle
    • Yu, L., L. Pena Castillo, S. Mnaimneh, T. R. Hughes, and G. W. Brown, 2006 A survey of essential gene function in the yeast cell division cycle. Mol. Biol. Cell 17: 4736-4747.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 4736-4747
    • Yu, L.1    Pena, C.L.2    Mnaimneh, S.3    Hughes, T.R.4    Brown, G.W.5
  • 144
    • 0035148461 scopus 로고    scopus 로고
    • Estimates of the rate and distribution of fitness effects of spontaneous mutation in Saccharomyces cerevisiae
    • Zeyl, C., and J. A. G. M. de Visser, 2001 Estimates of the rate and distribution of fitness effects of spontaneous mutation in Saccharomyces cerevisiae. Genetics 157: 53-61.
    • (2001) Genetics , vol.157 , pp. 53-61
    • Zeyl, C.1    de Visser, J.A.G.M.2
  • 145
    • 0037133566 scopus 로고    scopus 로고
    • The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1
    • Zhao, X., and R. Rothstein, 2002 The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1. Proc. Natl. Acad. Sci. USA 99: 3746-3751.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 3746-3751
    • Zhao, X.1    Rothstein, R.2
  • 146
    • 0027145127 scopus 로고
    • DUN1 encodes a protein kinase that controls the DNA damage response in yeast
    • Zhou, Z., and S. J. Elledge, 1993 DUN1 encodes a protein kinase that controls the DNA damage response in yeast. Cell 75: 1119-1127.
    • (1993) Cell , vol.75 , pp. 1119-1127
    • Zhou, Z.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.