Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins

Molecular and Cellular Biology

Volumn 17, Issue 5, 1997, Pages 2844-2850

  Greene, Christopher N ^a   Jinks Robertson, Sue ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL DNA; FUNGAL PROTEIN;

ARTICLE; DNA REPAIR; DNA REPLICATION; DNA SEQUENCE; FRAMESHIFT MUTATION; FUNGAL GENETICS; FUNGUS MUTANT; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; STRAIN DIFFERENCE; YEAST;

FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0030953472     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.5.2844     Document Type: Article

References (55)

1. Alani, E., L. Cao, and N. Kleckner. 1987. A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics 116:541-545.
2. Bebenek, K., and T. A. Kunkel. 1990. Frameshift errors initiated by nucleotide misincorporation. Proc. Natl. Acad. Sci. USA 87:4946-4950.
3. Boeke, J. D., J. Trueheart, G. Natsoulis, and G. R. Fink. 1987. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154:164-175.
4. Cariello, N. F., W. W. Piegorsch, W. T. Adams, and T. R. Skopek. 1994. Computer program for the analysis of mutational spectra: application to p53 mutations. Carcinogenesis 15:2281-2285.
5. Crouse, G. F. Mismatch repair systems in Saccharomyces cerevisiae. In J. A. Nickoloff and M. F. Hoekstra (ed.), DNA damage and repair, vol. 1. DNA repair in prokaryotes and lower eukaryotes, in press. Humana Press, Totowa, N.J.
6. Datta, A., A. Adjiri, L. New, G. F. Crouse, and S. Jinks-Robertson. 1996. Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:1085-1093.
7. Datta, A., and S. Jinks-Robertson. 1995. Association of increased spontaneous mutation rates with high levels of transcription in yeast. Science 268: 1616-1619.
8. Fishel, R., and R. D. Kolodner. 1995. Identification of mismatch repair genes and their role in the development of cancer. Curr. Opin. Genet. Dev. 5:382-395.
9. Geitz, D., A. St. Jean, R. A. Woods, and R. H. Schiestl. 1992. Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20:1425.
10. Giroux, C. N., J. R. A. Mis, M. K. Pierce, S. E. Kohalmi, and B. A. Kunz. 1988. DNA sequence analysis of spontaneous mutations in the SUP4-o gene of Saccharomyces cerevisiae. Mol. Cell. Biol. 8:978-981.
11. Glickman, B. W., and L. S. Ripley. 1984. Structural intermediates of deletion mutagenesis: a role for palindromic DNA. Proc. Natl. Acad. Sci. USA 81: 512-516.
12. Habraken, Y., P. Sung, L. Prakash, and S. Prakash. 1996. Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3. Curr. Biol. 6:1185-1187.
13. Hampsey, D. M., J. F. Ernst, J. W. Stewart, and F. Sherman. 1988. Multiple base-pair mutations in yeast. J. Mol. Biol. 201:471-486.
14. Henderson, S. T., and T. D. Petes. 1992. Instability of simple sequence DNA in Saccharomyces cerevisiae. Mol. Cell. Biol. 12:2749-2757.
15. Hoffman, C. S., and F. Winston. 1987. A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57:267-272.
16. Hollingsworth, N. M., L. Ponte, and C. Halsey. 1995. MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair. Genes Dev. 9:1728-1739.
17. Huang, J., N. Papadopoulos, A. J. McKinley, S. M. Farrington, L. J. Curtis, A. H. Wyllie, S. Zheng, J. K. V. Willson, S. D. Markowitz, P. Morin, K. W. Kinzler, B. Vogelstein, and M. G. Dunlop. 1996. APC mutations in colorectal tumors with mismatch repair deficiency. Proc. Natl. Acad. Sci. USA 93:9049-9054.
18. Iaccarino, I., F. Palombo, J. Drummond, N. F. Totty, J. J. Hsuan, P. Modrich, and J. Jiricny. 1996. MSH6, a Saccharomyces cerevisiae protein that binds to mismatches as a heterodimer with MSH2. Curr. Biol. 6:484-486.
19. Johnson, R. E., G. K. Kovvali, S. N. Guzder, N. S. Amin, C. Holm, Y. Habraken, P. Sung, L. Prakash, and S. Prakash. 1996. Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair. J. Biol. Chem. 271:27987-27990.
20. Johnson, R. E., G. K. Kowali, L. Prakash, and S. Prakash. 1996. Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stability. J. Biol. Chem. 271:7285-7288.
21. Kalinowski, D. P., F. W. Larimer, and M. J. Plewa. 1995. Analysis of spontaneous frameshift mutations in REV1 and rev1-1 strains of Saccharomyces cerevisiae. Mutat. Res. 331:149-159.
22. Kolodner, R. 1996. Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev. 10:1433-1442.
23. Kramer, W., B. Kramer, M. S. Williamson, and S. Fogel. 1989. Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB. J. Bacteriol. 171:5339-5346.
24. Kroutil, L. C., K. Register, K. Bebenek, and T. A. Kunkel. 1996. Exonucleolytic proofreading during replication of repetitive DNA. Biochemistry 35: 1046-1053.
25. Lea, D. E., and C. A. Coulson. 1949. The distribution of the numbers of mutants in bacterial populations. J. Genet. 49:264-285.
26. Lee, G. S.-F., E. A. Savage, R. G. Ritzel, and R. C. Von Borstel. 1988. The base-alteration spectrum of spontaneous and ultraviolet radiation-induced forward mutations in the URA3 locus of Saccharomyces cerevisiae. Mol. Gen. Genet. 214:396-404.
27. Longerich, S., A. M. Galloway, R. S. Harris, C. Wong, and S. M. Rosenberg. 1995. Adaptive mutation sequences reproduced by mismatch repair deficiency. Proc. Natl. Acad. Sci. USA 92:12017-12020.
28. Markowitz, S., J. Wang, L. Myeroff, R. Parsons, L. Sun, J. Lutterbaugh, R. S. Fan, E. Zborowska, K. W. Kinzler, B. Vogelstein, M. Brattain, and J. K. V. Willson. 1995. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science 268:1336-1338.
29. Marsischky, G. T., N. Filosi, M. F. Kane, and R. Kolodner. 1996. Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes Dev. 10:407-420.
30. Modrich, P., and R. Lahue. 1996. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu. Rev. Biochem. 65:101-133.
31. New, L., K. Liu, and G. F. Crouse. 1993. The yeast gene MSH3 defines a new class of eukaryotic MutS homologues. Mol. Gen. Genet. 239:97-108.
32. Pribnow, D., C. Sigurdson, L. Gold, B. S. Singer, C Napoli, J. Brosius, T. J. Dull, and H. F. Noller. 1981. rII cistrons of bacteriophage T4: DNA sequence around the intercistronic divide and position of genetic landmarks. J. Mol. Biol. 149:337-376.
33. Prolla, T. A., D.-M. Christie, and R. M. Liskay. 1994. Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene. Mol. Cell. Biol. 14:407-415.
34. Prolla, T. A., Q. Pang, E. Alani, R. D. Kolodner, and R. M. Liskay. 1994. MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science 265:1091-1093.
35. Quah, S.-K., R. C. Von Borstel, and P. J. Hastings. 1980. The origin of spontaneous mutation in Saccharomyces cerevisiae. Genetics 96:819-839.
36. Reenan, R. A. G., and R. D. Kolodner. 1992. Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochrondrial and nuclear functions. Genetics 132:975-985.
37. Ripley, L. S. 1990. Frameshift mutation: determinants of specificity. Annu. Rev. Genet. 24:189-213.
38. Ripley, L. S., A. Clark, and J. G. deBoer. 1986. Spectrum of spontaneous frameshift mutations: sequences of bacteriophage T4 rII gene frameshifts. J. Mol. Biol. 191:601-613.
39. Ross-Macdonald, P., and G. S. Roeder. 1994. Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction. Cell 79:1069-1080.
40. Rothstein, R. 1991. Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol. 194:281-301.
41. Schaaper, R. M., and R. L. Dunn. 1987. Spectra of spontaneous mutations in Escherichia coli strains defective in mismatch correction: the nature of in vivo DNA replication errors. Proc. Natl. Acad. Sci. USA 84:6220-6224.
42. Schaaper, R. M., and R. L. Dunn. 1991. Spontaneous mutation in the Escherichia coli lacI gene. Genetics 129:317-326.
43. Selva, E. M., L. New, G. F. Crouse, and R. S. Lahue. 1995. Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae. Genetics 139:1175-1188.
44. Sherman, F. 1991. Getting started with yeast. Methods Enzymol. 194:3-20.
45. Sia, E. A., R. J. Kokoska, M. Dominska, P. Greenwell, and T. D. Petes. 1997. Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes. Mol. Cell. Biol. 17:2851-2858.
46. Singer, B. S., and J. Westlye. 1988. Deletion formation in bacteriophage T4. J. Mol. Biol. 202:233-243.
47. Strand, M., M. C. Earley, G. F. Crouse, and T. D. Petes. 1995. Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 92: 10418-10421.
48. Strand, M., T. A. Prolla, R. M. Liskay, and T. D. Petes. 1993. Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 365:274-276.
49. Strathern, J. N., B. Shafer, and C. B. McGill. 1995. DNA synthesis errors associated with double-strand-break repair. Genetics 140:965-972.
50. Streisinger, G., Y. Okada, J. Emrich, J. Newton, A. Tsugita, E. Terzaghi, and M. Inouye. 1966. Frameshift mutations and the genetic code. Cold Spring Harbor Symp. Quant. Biol. 31:77-84.
51. Tran, H. T., N. P. Degtyareva, N. N. Koloteva, A. Sugino, H. Masumoto, D. A. Gordenin, and M. A. Resnick. 1995. Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes. Mol. Cell. Biol. 15:5607-5617.
52. Tran, H. T., D. A. Gordenin, and M. A. Resnick. 1996. The prevention of repeat-associated deletions in Saccharomyces cerevisiae by mismatch repair depends on size and origin of deletions. Genetics 143:1579-1587.
53. Tran, H. T., J. D. Keen, M. Kricker, M. A. Resnick, and D. A. Gordenin. 1997. Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants. Mol. Cell. Biol. 17:2859-2865.
54. Umar, A., A. B. Buermeyer, J. A. Simon, D. C. Thomas, A. B. Clark, R. M. Liskay, and T. A. Kunkel. 1996. Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis. Cell 87:65-73.
55. Umar, A., and T. A. Kunkel. 1996. DNA-replication fidelity, mismatch repair and genome instability in cancer cells. Eur. J. Biochem. 238:297-307.