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Volumn 20, Issue 10, 2001, Pages 2587-2595

Replication slippage involves DNA polymerase pausing and dissociation

Author keywords

Copy choice recombination; Direct repeats; DNA rearrangements; Palindrome; Replication slippage mechanism

Indexed keywords

DNA; DNA POLYMERASE; SINGLE STRANDED DNA;

EID: 0035872937     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.10.2587     Document Type: Article
Times cited : (236)

References (52)
  • 1
    • 0033952567 scopus 로고    scopus 로고
    • Lesions in DNA: Hurdles for polymerases
    • Baynton, K. and Fuchs, R.P. (2000) Lesions in DNA: hurdles for polymerases. Trends Biochem. Sci., 25, 74-79.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 74-79
    • Baynton, K.1    Fuchs, R.P.2
  • 2
    • 0027215750 scopus 로고
    • Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding and termination probability to mutational hot spots
    • Bebenek, K., Abbotts, J., Wilson, S.H. and Kunkel, T.A. (1993) Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding and termination probability to mutational hot spots. J. Biol. Chem., 268, 10324-10334.
    • (1993) J. Biol. Chem. , vol.268 , pp. 10324-10334
    • Bebenek, K.1    Abbotts, J.2    Wilson, S.H.3    Kunkel, T.A.4
  • 3
    • 0024458717 scopus 로고
    • Sequence-specific pausing during in vitro DNA replication on double-stranded DNA templates
    • Bedinger, P., Munn, M. and Alberts, B.M. (1989) Sequence-specific pausing during in vitro DNA replication on double-stranded DNA templates. J. Biol. Chem., 264, 16880-16886.
    • (1989) J. Biol. Chem. , vol.264 , pp. 16880-16886
    • Bedinger, P.1    Munn, M.2    Alberts, B.M.3
  • 4
    • 0028346421 scopus 로고
    • When replication forks stop
    • Bierne, H. and Michel, B. (1994) When replication forks stop. Mol. Microbiol., 13, 17-23.
    • (1994) Mol. Microbiol. , vol.13 , pp. 17-23
    • Bierne, H.1    Michel, B.2
  • 5
    • 0025769924 scopus 로고
    • The replication termination signal terB of the Escherichia coli chromosome is a deletion hot spot
    • Bierne, H., Ehrlich, S.D. and Michel, B. (1991) The replication termination signal terB of the Escherichia coli chromosome is a deletion hot spot. EMBO J., 10, 2699-2705.
    • (1991) EMBO J. , vol.10 , pp. 2699-2705
    • Bierne, H.1    Ehrlich, S.D.2    Michel, B.3
  • 6
    • 0030946855 scopus 로고    scopus 로고
    • Deletions at stalled replication forks occur by two different pathways
    • Bierne, H., Ehrlich, S.D. and Michel, B. (1997a) Deletions at stalled replication forks occur by two different pathways. EMBO J., 16, 3332-3340.
    • (1997) EMBO J. , vol.16 , pp. 3332-3340
    • Bierne, H.1    Ehrlich, S.D.2    Michel, B.3
  • 7
    • 0030844430 scopus 로고    scopus 로고
    • Isolation of a dnaE mutation which enhances RecA-independent homologous recombination in the Escherichia coli chromosome
    • Bierne, H., Vilette, D., Ehrlich, S.D. and Michel, B. (1997b) Isolation of a dnaE mutation which enhances RecA-independent homologous recombination in the Escherichia coli chromosome. Mol. Microbiol., 24, 1225-1234.
    • (1997) Mol. Microbiol. , vol.24 , pp. 1225-1234
    • Bierne, H.1    Vilette, D.2    Ehrlich, S.D.3    Michel, B.4
  • 8
    • 0030003386 scopus 로고    scopus 로고
    • Copy-choice recombination mediated by DNA polymerase III holoenzyme from Escherichia coli
    • Canceill, D. and Ehrlich, S.D. (1996) Copy-choice recombination mediated by DNA polymerase III holoenzyme from Escherichia coli. Proc. Natl Acad. Sci. USA, 93, 6647-6652.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 6647-6652
    • Canceill, D.1    Ehrlich, S.D.2
  • 9
    • 0033600752 scopus 로고    scopus 로고
    • Replication slippage of different DNA polymerases is inversely related to their strand displacement efficiency
    • Canceill, D., Viguera, E. and Ehrlich, S.D. (1999) Replication slippage of different DNA polymerases is inversely related to their strand displacement efficiency. J. Biol. Chem., 274, 27481-27490.
    • (1999) J. Biol. Chem. , vol.274 , pp. 27481-27490
    • Canceill, D.1    Viguera, E.2    Ehrlich, S.D.3
  • 10
    • 0033960606 scopus 로고    scopus 로고
    • Palindromes as substrates for multiple pathways of recombination in Escherichia coli
    • Cromie, G.A., Millar, C.B., Schmidt, K.H. and Leach, D.R. (2000) Palindromes as substrates for multiple pathways of recombination in Escherichia coli. Genetics, 154, 513-522.
    • (2000) Genetics , vol.154 , pp. 513-522
    • Cromie, G.A.1    Millar, C.B.2    Schmidt, K.H.3    Leach, D.R.4
  • 12
    • 0032498304 scopus 로고    scopus 로고
    • Evidence for two preferred hairpin folding patterns in d(CGG).d(CCG) repeat tracts in vivo
    • Darlow, J.M. and Leach, D.R. (1998) Evidence for two preferred hairpin folding patterns in d(CGG).d(CCG) repeat tracts in vivo. J. Mol. Biol., 275, 17-23.
    • (1998) J. Mol. Biol. , vol.275 , pp. 17-23
    • Darlow, J.M.1    Leach, D.R.2
  • 13
    • 0028357737 scopus 로고
    • Coordination of leading and lagging strand DNA synthesis at the replication fork of bacteriophage T7
    • Debyser, Z., Tabor, S. and Richardson, C.C. (1994) Coordination of leading and lagging strand DNA synthesis at the replication fork of bacteriophage T7. Cell, 77, 157-166.
    • (1994) Cell , vol.77 , pp. 157-166
    • Debyser, Z.1    Tabor, S.2    Richardson, C.C.3
  • 14
    • 0032563245 scopus 로고    scopus 로고
    • Evolution of simple repeats in DNA and their relation to human disease
    • Djian, P. (1998) Evolution of simple repeats in DNA and their relation to human disease. Cell, 94, 155-160.
    • (1998) Cell , vol.94 , pp. 155-160
    • Djian, P.1
  • 16
    • 0034705095 scopus 로고    scopus 로고
    • The many faces of DNA polymerases: Strategies for mutagenesis and for mutational avoidance
    • Friedberg, E.C., Feaver, W.J. and Gerlach, V.L. (2000) The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidance. Proc. Natl Acad. Sci. USA, 97, 5681-5683.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 5681-5683
    • Friedberg, E.C.1    Feaver, W.J.2    Gerlach, V.L.3
  • 17
    • 0028147234 scopus 로고
    • The rapid dissociation of the T4 DNA polymerase holoenzyme when stopped by a DNA hairpin helix. A model for polymerase release following the termination of each Okazaki fragment
    • Hacker, K.J. and Alberts, B.M. (1994) The rapid dissociation of the T4 DNA polymerase holoenzyme when stopped by a DNA hairpin helix. A model for polymerase release following the termination of each Okazaki fragment. J. Biol. Chem., 269, 24221-24228.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24221-24228
    • Hacker, K.J.1    Alberts, B.M.2
  • 18
    • 0345487521 scopus 로고    scopus 로고
    • Trinucleotide expansion diseases in the context of micro-and minisatellite evolution
    • Hancock, J.M. and Sanlibanez-Koref, M.F. (1998) Trinucleotide expansion diseases in the context of micro-and minisatellite evolution. EMBO J., 17, 5521-5524.
    • (1998) EMBO J. , vol.17 , pp. 5521-5524
    • Hancock, J.M.1    Sanlibanez-Koref, M.F.2
  • 19
    • 0034674476 scopus 로고    scopus 로고
    • Base stacking and even/odd behavior of hairpin loops in DNA triplet repeat slippage and expansion with DNA polymerase
    • Hartenstine, M.J., Goodman, M.F. and Petruska, J. (2000) Base stacking and even/odd behavior of hairpin loops in DNA triplet repeat slippage and expansion with DNA polymerase. J. Biol. Chem., 275, 18382-18390.
    • (2000) J. Biol. Chem. , vol.275 , pp. 18382-18390
    • Hartenstine, M.J.1    Goodman, M.F.2    Petruska, J.3
  • 20
    • 0028807448 scopus 로고
    • Pausing of DNA synthesis in vitro at specific loci in CTG and CGG triplet repeats from human hereditary disease genes
    • Kang, S., Ohshima, K., Shimizu, M., Amirhaeri, S. and Wells, R.D. (1995) Pausing of DNA synthesis in vitro at specific loci in CTG and CGG triplet repeats from human hereditary disease genes. J. Biol. Chem., 270, 27014-27021.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27014-27021
    • Kang, S.1    Ohshima, K.2    Shimizu, M.3    Amirhaeri, S.4    Wells, R.D.5
  • 21
    • 0021112633 scopus 로고
    • Site-specific pausing of deoxyribonucleic acid synthesis catalyzed by four forms of Escherichia coli DNA polymerase III
    • LaDuca, R.J., Fay, P.J., Chuang, C., McHenry, C.S. and Bambara, R.A. (1983) Site-specific pausing of deoxyribonucleic acid synthesis catalyzed by four forms of Escherichia coli DNA polymerase III. Biochemistry, 22, 5177-5188.
    • (1983) Biochemistry , vol.22 , pp. 5177-5188
    • LaDuca, R.J.1    Fay, P.J.2    Chuang, C.3    McHenry, C.S.4    Bambara, R.A.5
  • 22
    • 0028674914 scopus 로고
    • Long DNA palindromes, cruciform structures, genetic instability and secondary structure repair
    • Leach, D.R. (1994) Long DNA palindromes, cruciform structures, genetic instability and secondary structure repair. BioEssavs, 16, 893-900.
    • (1994) BioEssavs , vol.16 , pp. 893-900
    • Leach, D.R.1
  • 23
    • 0027420692 scopus 로고
    • A sister-strand exchange mechanism for recA-independent deletion of repeated DNA sequences in Escherichia coli
    • Lovett, S.T., Drapkin, P.T., Sutera, V.A., Jr and Gluckman-Peskind, T.J. (1993) A sister-strand exchange mechanism for recA-independent deletion of repeated DNA sequences in Escherichia coli. Genetics, 135, 631-642.
    • (1993) Genetics , vol.135 , pp. 631-642
    • Lovett, S.T.1    Drapkin, P.T.2    Sutera V.A., Jr.3    Gluckman-Peskind, T.J.4
  • 24
    • 0025997154 scopus 로고
    • DNA polymerase III holoenzyme. Components, structure and mechanism of a true replicative complex
    • McHenry, C.S. (1991) DNA polymerase III holoenzyme. Components, structure and mechanism of a true replicative complex. J. Biol. Chem., 266, 19127-19130.
    • (1991) J. Biol. Chem. , vol.266 , pp. 19127-19130
    • McHenry, C.S.1
  • 25
    • 0034176967 scopus 로고    scopus 로고
    • Replication fork arrest and DNA recombination
    • Michel, B. (2000) Replication fork arrest and DNA recombination. Trends Biochem. Sci., 25, 173-178.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 173-178
    • Michel, B.1
  • 26
    • 0030737538 scopus 로고    scopus 로고
    • Trinucleotide repeats associated with human disease
    • Mitas, M. (1997) Trinucleotide repeats associated with human disease. Nucleic Acids Res., 25, 2245-2254.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2245-2254
    • Mitas, M.1
  • 27
    • 0028805078 scopus 로고
    • 15 forms a heat-stable hairpin containing Gsyn-Ganti base pairs
    • 15 forms a heat-stable hairpin containing Gsyn-Ganti base pairs. Biochemistry, 34, 12803-12811.
    • (1995) Biochemistry , vol.34 , pp. 12803-12811
    • Mitas, M.1    Yu, A.2    Dill, J.3    Haworth, I.S.4
  • 29
    • 0034669125 scopus 로고    scopus 로고
    • All three SOS-inducible DNA polymerases (pol II, pol IV and pol V) are involved in induced mutagenesis
    • Napolitano, R., Janel-Bintz, R., Wagner, J. and Fuchs, R.P. (2000) All three SOS-inducible DNA polymerases (pol II, pol IV and pol V) are involved in induced mutagenesis. EMBO J., 19, 6259-6265.
    • (2000) EMBO J. , vol.19 , pp. 6259-6265
    • Napolitano, R.1    Janel-Bintz, R.2    Wagner, J.3    Fuchs, R.P.4
  • 30
    • 0023646086 scopus 로고
    • Accessory proteins bind a primed template and mediate rapid cycling of DNA polymerase III holoenzyme from Escherichia coli
    • O'Donnell, M.E. (1987) Accessory proteins bind a primed template and mediate rapid cycling of DNA polymerase III holoenzyme from Escherichia coli. J. Biol. Chem., 262, 16558-16565.
    • (1987) J. Biol. Chem. , vol.262 , pp. 16558-16565
    • O'Donnell, M.E.1
  • 31
    • 0025192952 scopus 로고
    • Total reconstitution of DNA polymerase III holoenzyme reveals dual accessory protein clamps
    • O'Donnell, M. and Studwell, P.S. (1990) Total reconstitution of DNA polymerase III holoenzyme reveals dual accessory protein clamps. J. Biol. Chem., 265, 1179-1187.
    • (1990) J. Biol. Chem. , vol.265 , pp. 1179-1187
    • O'Donnell, M.1    Studwell, P.S.2
  • 32
    • 0030836589 scopus 로고    scopus 로고
    • Hairpin formation during DNA synthesis primer realignment in vitro in triplet repeat sequences from human hereditary disease genes
    • Ohshima, K. and Wells, R.D. (1997) Hairpin formation during DNA synthesis primer realignment in vitro in triplet repeat sequences from human hereditary disease genes. J. Biol. Chem., 272, 16798-16806.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16798-16806
    • Ohshima, K.1    Wells, R.D.2
  • 33
    • 0001497645 scopus 로고    scopus 로고
    • In vitro DNA synthesis of triplet repeat sequences
    • Wells, R.D. and Warren, S.T. (eds), Academic Press, San Diego, CA
    • Ohshima, K. and Wells, R. (1998) In vitro DNA synthesis of triplet repeat sequences. In Wells, R.D. and Warren, S.T. (eds), Genetic Instabilities and Hereditary Neurological Diseases. Academic Press, San Diego, CA, pp. 717-735.
    • (1998) Genetic Instabilities and Hereditary Neurological Diseases , pp. 717-735
    • Ohshima, K.1    Wells, R.2
  • 34
    • 0000486352 scopus 로고    scopus 로고
    • Slipped strand DNA, dynamic mutations and human disease
    • Wells, R.D. and Warren, S.T. (eds), Academic Press, San Diego, CA
    • Pearson, C.E. and Sinden, R.R. (1998a) Slipped strand DNA, dynamic mutations and human disease. In Wells, R.D. and Warren, S.T. (eds), Genetic Instabilities and Hereditary Neurological Diseases. Academic Press, San Diego, CA, pp. 585-621.
    • (1998) Genetic Instabilities and Hereditary Neurological Diseases , pp. 585-621
    • Pearson, C.E.1    Sinden, R.R.2
  • 35
    • 0032102835 scopus 로고    scopus 로고
    • Trinucleotide repeat DNA structures: Dynamic mutations from dynamic DNA
    • Pearson, C.E. and Sinden, R.R. (1998b) Trinucleotide repeat DNA structures: dynamic mutations from dynamic DNA. Curr. Opin. Struct. Biol., 8, 321-330.
    • (1998) Curr. Opin. Struct. Biol. , vol.8 , pp. 321-330
    • Pearson, C.E.1    Sinden, R.R.2
  • 36
    • 0032570797 scopus 로고    scopus 로고
    • Analysis of strand slippage in DNA polymerase expansions of CAG/CTG triplet repeats associated with neurodegenerative disease
    • Petruska, J., Hartenstine, M.J. and Goodman, M.F. (1998) Analysis of strand slippage in DNA polymerase expansions of CAG/CTG triplet repeats associated with neurodegenerative disease. J. Biol Chem., 273, 5204-5210.
    • (1998) J. Biol Chem. , vol.273 , pp. 5204-5210
    • Petruska, J.1    Hartenstine, M.J.2    Goodman, M.F.3
  • 37
    • 0031803630 scopus 로고    scopus 로고
    • Replication strand preference for deletions associated with DNA palindromes
    • Pinder, D.J., Blake, C.E., Lindsey, J.C. and Leach, D.R. (1998) Replication strand preference for deletions associated with DNA palindromes. Mol. Microbiol., 28, 719-727.
    • (1998) Mol. Microbiol. , vol.28 , pp. 719-727
    • Pinder, D.J.1    Blake, C.E.2    Lindsey, J.C.3    Leach, D.R.4
  • 38
    • 0026643492 scopus 로고
    • Processive proofreading is intrinsic to T4 DNA polymerase
    • Reddy, M.K., Weitzel, S.E. and von Hippel, P.H. (1992) Processive proofreading is intrinsic to T4 DNA polymerase. J. Biol. Chem., 267, 14157-14166.
    • (1992) J. Biol. Chem. , vol.267 , pp. 14157-14166
    • Reddy, M.K.1    Weitzel, S.E.2    Von Hippel, P.H.3
  • 39
    • 0026767610 scopus 로고
    • Dynamic mutations: A new class of mutations causing human disease
    • Richards, R.I. and Sutherland, G.R. (1992) Dynamic mutations: a new class of mutations causing human disease. Cell, 70, 709-712.
    • (1992) Cell , vol.70 , pp. 709-712
    • Richards, R.I.1    Sutherland, G.R.2
  • 40
    • 0028242797 scopus 로고
    • Simple repeat DNA is not replicated simply
    • Richards, R.I. and Sutherland, G.R. (1994) Simple repeat DNA is not replicated simply. Nature Genet., 6, 114-116.
    • (1994) Nature Genet. , vol.6 , pp. 114-116
    • Richards, R.I.1    Sutherland, G.R.2
  • 41
    • 0030725454 scopus 로고    scopus 로고
    • Trinucleotide repeats affect DNA replication in vivo
    • Samadashwily, G.M., Raca, G. and Mirkin, S.M. (1997) Trinucleotide repeats affect DNA replication in vivo. Nature Genet., 17, 298-304.
    • (1997) Nature Genet. , vol.17 , pp. 298-304
    • Samadashwily, G.M.1    Raca, G.2    Mirkin, S.M.3
  • 42
    • 0033585124 scopus 로고    scopus 로고
    • Strand asymmetry of +1 frameshift mutagenesis at a homopolymeric run by DNA polymerase III holoenzyme of Escherichia coli
    • Seki, M., Akiyama, M., Sugaya, Y., Ohtsubo, E. and Maki, H. (1999) Strand asymmetry of +1 frameshift mutagenesis at a homopolymeric run by DNA polymerase III holoenzyme of Escherichia coli. J. Biol. Chem., 274, 33313-33319.
    • (1999) J. Biol. Chem. , vol.274 , pp. 33313-33319
    • Seki, M.1    Akiyama, M.2    Sugaya, Y.3    Ohtsubo, E.4    Maki, H.5
  • 43
    • 0026352538 scopus 로고
    • On the deletion of inverted repeated DNA in Escherichia coli: Effects of length, thermal stability and cruciform formation in vivo
    • Sinden, R.R., Zheng, G.X., Brankamp, R.G. and Allen, K.N. (1991) On the deletion of inverted repeated DNA in Escherichia coli: effects of length, thermal stability and cruciform formation in vivo. Genetics, 129, 991-1005.
    • (1991) Genetics , vol.129 , pp. 991-1005
    • Sinden, R.R.1    Zheng, G.X.2    Brankamp, R.G.3    Allen, K.N.4
  • 44
    • 0032774402 scopus 로고    scopus 로고
    • DNA-directed mutations. Leading and lagging strand specificity
    • Sinden, R.R., Hashem, V.I. and Rosche, W.A. (1999) DNA-directed mutations. Leading and lagging strand specificity. Ann. N. Y. Acad. Sci., 870, 173-189.
    • (1999) Ann. N. Y. Acad. Sci. , vol.870 , pp. 173-189
    • Sinden, R.R.1    Hashem, V.I.2    Rosche, W.A.3
  • 45
    • 0033369989 scopus 로고    scopus 로고
    • Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats
    • Spiro, C. et al. (1999) Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats. Mol. Cell, 4, 1079-1085.
    • (1999) Mol. Cell , vol.4 , pp. 1079-1085
    • Spiro, C.1
  • 47
    • 0033858199 scopus 로고    scopus 로고
    • Microsatellites in different eukaryotic genomes: Survey and analysis
    • Toth, G., Gaspari, Z. and Jurka, J. (2000) Microsatellites in different eukaryotic genomes: survey and analysis. Genome Res., 10, 967-981.
    • (2000) Genome Res. , vol.10 , pp. 967-981
    • Toth, G.1    Gaspari, Z.2    Jurka, J.3
  • 49
    • 0020490330 scopus 로고
    • Specific sequences in native DNA that arrest synthesis by DNA polymerase α
    • Weaver, D.T. and DePamphilis, M.L. (1982) Specific sequences in native DNA that arrest synthesis by DNA polymerase α. J. Biol. Chem., 257, 2075-2086.
    • (1982) J. Biol. Chem. , vol.257 , pp. 2075-2086
    • Weaver, D.T.1    DePamphilis, M.L.2
  • 50
    • 0021633812 scopus 로고
    • The role of palindromic and non-palindromic sequences in arresting DNA synthesis in vitro and in vivo
    • Weaver, D.T. and DePamphilis, M.L. (1984) The role of palindromic and non-palindromic sequences in arresting DNA synthesis in vitro and in vivo. J. Mol. Biol., 180, 961-986.
    • (1984) J. Mol. Biol. , vol.180 , pp. 961-986
    • Weaver, D.T.1    DePamphilis, M.L.2
  • 51
    • 0030058075 scopus 로고    scopus 로고
    • Molecular basis of genetic instability of triplet repeats
    • Wells, R.D. (1996) Molecular basis of genetic instability of triplet repeats. J. Biol. Chem., 271, 2875-2878.
    • (1996) J. Biol. Chem. , vol.271 , pp. 2875-2878
    • Wells, R.D.1
  • 52
    • 0033968254 scopus 로고    scopus 로고
    • Dynamics of β and proliferating cell nuclear antigen sliding clamps in traversing DNA secondary structure
    • Yao, N., Hurwitz, J. and O'Donnell, M. (2000) Dynamics of β and proliferating cell nuclear antigen sliding clamps in traversing DNA secondary structure. J. Biol. Chem., 275, 1421-1432.
    • (2000) J. Biol. Chem. , vol.275 , pp. 1421-1432
    • Yao, N.1    Hurwitz, J.2    O'Donnell, M.3


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