Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

Nucleic Acids Research

Volumn 41, Issue 5, 2013, Pages 3257-3273

  Moreno, Pedro M D ^a,b,d   Geny, Sylvain ^a   Pabon, Y Vladimir ^a   Bergquist, Helen ^a   Zaghloul, Eman M ^a,b   Rocha, Cristina S J ^a   Oprea, Iulian I ^a   Bestas, Burcu ^a   Andaloussi, Samir El ^a   Jørgensen, Per T ^c   Pedersen, Erik B ^c   Lundin, Karin E ^a   Zain, Rula ^a   Wengel, Jesper ^c   Smith, C I Edvard ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Alexandria University Faculty of Pharmacy   (Egypt)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d INEB INSTITUTO DE ENGENHARIA BIOMÉDICA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

BIS LOCKED NUCLEIC ACID; DOUBLE STRANDED DNA; ION; LOCKED NUCLEIC ACID; OLIGONUCLEOTIDE; PLASMID DNA; SUPERCOILED DUPLEX DNA; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHROMOSOME; CONTROLLED STUDY; DNA FLANKING REGION; DNA SUPERCOILING; GENE TARGETING; GENETIC PROCEDURES; INVASION INTO DOUBLE STRANDED DNA; MELTING POINT; PH; PRIORITY JOURNAL;

BASE PAIRING; BASE SEQUENCE; BINDING SITES; BUFFERS; DNA; DNA CLEAVAGE; DNA RESTRICTION ENZYMES; DNA, SUPERHELICAL; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; PLASMIDS; TRANSITION TEMPERATURE;

EID: 84876401355     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt007     Document Type: Article

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