Optimizing anti-gene oligonucleotide 'Zorro-LNA' for improved strand invasion into duplex DNA

Nucleic Acids Research

Volumn 39, Issue 3, 2011, Pages 1142-1154

  Zaghloul, Eman M ^a   Madsen, Andreas S ^b   Moreno, Pedro M D ^a   Oprea, Iulian I ^a,c   El Andaloussi, Samir ^a   Bestas, Burcu ^a   Gupta, Pankaj ^b   Pedersen, Erik B ^b   Lundin, Karin E ^a   Wengel, Jesper ^b   Smith, C I Edvard ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

3' 5' 5' 3' SINGLE STRANDED ZORRO; 3' PHOSPHORAMIDOUS ACID; 5' PHOSPHORAMIDOUS ACID; ANTISENSE OLIGONUCLEOTIDE; CARBON; DOUBLE STRANDED DNA; LOCKED NUCLEIC ACID; MACROGOL; NUCLEOTIDE; PHOSPHORAMIDOUS ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL COMPOSITION; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROPHILICITY; PRIORITY JOURNAL;

DNA; GENE SILENCING; NUCLEIC ACID HYBRIDIZATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDES; PLASMIDS;

EID: 79951570868     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq835     Document Type: Article

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