메뉴 건너뛰기




Volumn 31, Issue 20, 2003, Pages 5817-5830

Use of locked nucleic acid oligonucleotides to add functionality to plasmid DNA

Author keywords

[No Author keywords available]

Indexed keywords

CATION; DNA VACCINE; DOUBLE STRANDED DNA; IMMUNOMODULATING AGENT; LIPID; NUCLEIC ACID; OLIGONUCLEOTIDE; PEPTIDE NUCLEIC ACID; PHOSPHOROTHIOIC ACID; PLASMID DNA; REAGENT; TUMOR NECROSIS FACTOR ALPHA;

EID: 0344874534     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg801     Document Type: Article
Times cited : (39)

References (44)
  • 1
    • 0035287212 scopus 로고    scopus 로고
    • Enhanced gene delivery to human airway epithelial cells using an integrin-targeting lipoplex
    • Scott,E., Wiseman,J., Evans,M. and Colledge,W.H. (2001) Enhanced gene delivery to human airway epithelial cells using an integrin-targeting lipoplex. J. Gene Med., 3, 125-134.
    • (2001) J. Gene Med. , vol.3 , pp. 125-134
    • Scott, E.1    Wiseman, J.2    Evans, M.3    Colledge, W.H.4
  • 2
    • 0036190843 scopus 로고    scopus 로고
    • Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems
    • Cartier,R. and Reszka,R. (2002) Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems. Gene Ther., 9, 157-167.
    • (2002) Gene Ther. , vol.9 , pp. 157-167
    • Cartier, R.1    Reszka, R.2
  • 3
    • 0032894156 scopus 로고    scopus 로고
    • Coupling of nuclear localization signals to plasmid DNA and specific interaction of the conjugates with importin α
    • Ciolina,C., Byk,G., Blanche,F., Thuiller,V., Scherman,D. and Wils,P. (1999) Coupling of nuclear localization signals to plasmid DNA and specific interaction of the conjugates with importin α. Bioconj. Chem., 10, 49-55.
    • (1999) Bioconj. Chem. , vol.10 , pp. 49-55
    • Ciolina, C.1    Byk, G.2    Blanche, F.3    Thuiller, V.4    Scherman, D.5    Wils, P.6
  • 5
    • 0032806151 scopus 로고    scopus 로고
    • Coupling of a targeting peptide to plasmid DNA by covalent triple helix formation
    • Neves,C., Byk,G., Scherman,D. and Wils,P. (1999) Coupling of a targeting peptide to plasmid DNA by covalent triple helix formation. FEBS Lett., 453, 41-45.
    • (1999) FEBS Lett. , vol.453 , pp. 41-45
    • Neves, C.1    Byk, G.2    Scherman, D.3    Wils, P.4
  • 6
    • 0033524453 scopus 로고    scopus 로고
    • Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus
    • Zanta,M., Belguise-Valladier,P. and Behr,J.P. (1999) Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc. Natl Acad. Sci. USA, 96, 91-96.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 91-96
    • Zanta, M.1    Belguise-Valladier, P.2    Behr, J.P.3
  • 7
    • 0034945237 scopus 로고    scopus 로고
    • Priming of immune responses to hepatitis B surface antigen with minimal DNA expression constructs modified with a nuclear localization signal peptide
    • Schirmbeck,R., Konig-Merediz,S., Riedl,P., Kwissa,M., Sack,F., Schroff,M., Junghans,C., Reimann,J. and Wittig,B. (2001) Priming of immune responses to hepatitis B surface antigen with minimal DNA expression constructs modified with a nuclear localization signal peptide. J. Mol. Med., 79, 343-350.
    • (2001) J. Mol. Med. , vol.79 , pp. 343-350
    • Schirmbeck, R.1    Konig-Merediz, S.2    Riedl, P.3    Kwissa, M.4    Sack, F.5    Schroff, M.6    Junghans, C.7    Reimann, J.8    Wittig, B.9
  • 8
    • 0032958001 scopus 로고    scopus 로고
    • Gene chemistry: Functionally and conformationally intact fluorescent plasmid DNA
    • Zelphati,O., Liang,X., Hobart,P. and Felgner,P. (1999) Gene chemistry: functionally and conformationally intact fluorescent plasmid DNA. Hum. Gene Ther., 10, 15-24.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 15-24
    • Zelphati, O.1    Liang, X.2    Hobart, P.3    Felgner, P.4
  • 9
    • 0033964669 scopus 로고    scopus 로고
    • PNA-dependent gene chemistry: Stable coupling of peptides and oligonucleotides to plasmid DNA
    • Zelphati,O., Liang,X., Nguyen,C., Barlow,S., Sheng,S., Shao,Z. and Felgner,P. (2000) PNA-dependent gene chemistry: stable coupling of peptides and oligonucleotides to plasmid DNA. Biotechniques, 28, 304-316.
    • (2000) Biotechniques , vol.28 , pp. 304-316
    • Zelphati, O.1    Liang, X.2    Nguyen, C.3    Barlow, S.4    Sheng, S.5    Shao, Z.6    Felgner, P.7
  • 10
    • 0344751591 scopus 로고    scopus 로고
    • Patent WO 02/102825 A2; PCT/GB02/02728
    • Catchpole,I. (2002) Patent WO 02/102825 A2; PCT/GB02/02728.
    • (2002)
    • Catchpole, I.1
  • 11
    • 0035113736 scopus 로고    scopus 로고
    • Locked nucleic acid (LNA), fine tuning the recognition of DNA and RNA
    • Braasch,D. and Corey,D. (2001) Locked nucleic acid (LNA), fine tuning the recognition of DNA and RNA. Chem. Biol., 8, 1-7.
    • (2001) Chem. Biol. , vol.8 , pp. 1-7
    • Braasch, D.1    Corey, D.2
  • 13
    • 0036924811 scopus 로고    scopus 로고
    • Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: Effect of mRNA target sequence and chimera design
    • Braasch,D., Liu,Y. and Corey,D. (2002) Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design. Nucleic Acids Res., 30, 5160-5167.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 5160-5167
    • Braasch, D.1    Liu, Y.2    Corey, D.3
  • 14
    • 0036730530 scopus 로고    scopus 로고
    • Single nucleotide polymorphism genotyping using short, fluorescently labeled locked nucleic acid (LNA) probes and fluorescence polarization detection
    • Simeonov,A. and Nikiforov,T. (2002) Single nucleotide polymorphism genotyping using short, fluorescently labeled locked nucleic acid (LNA) probes and fluorescence polarization detection. Nucleic Acids Res., 30, e91.
    • (2002) Nucleic Acids Res. , vol.30
    • Simeonov, A.1    Nikiforov, T.2
  • 15
    • 0037212106 scopus 로고    scopus 로고
    • PNA and LNA throw light on DNA
    • Demidov,V. (2002) PNA and LNA throw light on DNA. Trends Biotechnol., 21, 4-7.
    • (2002) Trends Biotechnol. , vol.21 , pp. 4-7
    • Demidov, V.1
  • 16
    • 0036567147 scopus 로고    scopus 로고
    • Design of antisense oligonucleotides stabilized by locked nucleic acids
    • Kurreck,J., Wyszko,E., Gillen,C. and Erdmann,V. (2002) Design of antisense oligonucleotides stabilized by locked nucleic acids. Nucleic Acids Res., 30, 1911-1918.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1911-1918
    • Kurreck, J.1    Wyszko, E.2    Gillen, C.3    Erdmann, V.4
  • 17
    • 0036606669 scopus 로고    scopus 로고
    • Design and characterization of decoy oligonucleotides containing locked nucleic acids
    • Crinelli,R., Bianchi,M., Gentilini,L. and Magnani,M. (2002) Design and characterization of decoy oligonucleotides containing locked nucleic acids. Nucleic Acids Res., 30, 2435-2443.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 2435-2443
    • Crinelli, R.1    Bianchi, M.2    Gentilini, L.3    Magnani, M.4
  • 18
    • 0035951767 scopus 로고    scopus 로고
    • 2′-O,4′-C-Methylene bridged nucleic acid modification promotes pyrimidine motif triplex formation at physiological pH
    • Torigue,H., Hari,Y., Sekiguchi,M., Obika,S. and Imanishi,T. (2001) 2′-O,4′-C-Methylene bridged nucleic acid modification promotes pyrimidine motif triplex formation at physiological pH. J. Biol. Chem., 276, 2354-2360.
    • (2001) J. Biol. Chem. , vol.276 , pp. 2354-2360
    • Torigue, H.1    Hari, Y.2    Sekiguchi, M.3    Obika, S.4    Imanishi, T.5
  • 19
    • 0034620259 scopus 로고    scopus 로고
    • Triplex formation by an oligonucleotide containing conformationally locked C-nucleoside, 5-(2′-O,4′-C-methylene-β-D-ribofuranosyl) oxazole
    • Obika,S., Hari,Y., Morio,K. and Imanishi,T. (2000) Triplex formation by an oligonucleotide containing conformationally locked C-nucleoside, 5-(2′-O,4′-C-methylene-β-D-ribofuranosyl) oxazole. Tetrahedron Lett., 41, 221-224.
    • (2000) Tetrahedron Lett. , vol.41 , pp. 221-224
    • Obika, S.1    Hari, Y.2    Morio, K.3    Imanishi, T.4
  • 21
    • 0034283848 scopus 로고    scopus 로고
    • Strand invasion by mixed base PNAs and a PNA-peptide chimera
    • Zhang,X., Ishihara,T. and Corey,D. (2000) Strand invasion by mixed base PNAs and a PNA-peptide chimera. Nucleic Acids Res., 28, 3332-3338.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 3332-3338
    • Zhang, X.1    Ishihara, T.2    Corey, D.3
  • 22
    • 0029829006 scopus 로고    scopus 로고
    • Enhancement of strand invasion by oligonucleotides through manipulation of backbone charge
    • Smulevitch,S., Simmons,C., Norton,J., Wise,T. and Corey,D. (1996) Enhancement of strand invasion by oligonucleotides through manipulation of backbone charge. Nat. Biotechnol., 14, 1700-1704.
    • (1996) Nat. Biotechnol. , vol.14 , pp. 1700-1704
    • Smulevitch, S.1    Simmons, C.2    Norton, J.3    Wise, T.4    Corey, D.5
  • 23
    • 0034623661 scopus 로고    scopus 로고
    • Immune effects and mechanisms of action of CpG motifs
    • Kreig,A. (2001) Immune effects and mechanisms of action of CpG motifs. Vaccine, 19, 618-622.
    • (2001) Vaccine , vol.19 , pp. 618-622
    • Kreig, A.1
  • 24
    • 0033997899 scopus 로고    scopus 로고
    • CpG DNA induces stronger immune responses with less toxicity than other adjuvants
    • Weeratna,R., McCluskie,M., Xu,Y. and Davis,H. (2000) CpG DNA induces stronger immune responses with less toxicity than other adjuvants. Vaccine, 18, 1755-1762.
    • (2000) Vaccine , vol.18 , pp. 1755-1762
    • Weeratna, R.1    McCluskie, M.2    Xu, Y.3    Davis, H.4
  • 27
    • 0032476602 scopus 로고    scopus 로고
    • CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
    • Hacker,H., Mischak,H., Miethke,T., Liptay,S., Schmid,R., Sparwasser,T., Heeg,K., Lipford,G. and Wagner,H. (1998) CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J., 17, 6230-6240.
    • (1998) EMBO J. , vol.17 , pp. 6230-6240
    • Hacker, H.1    Mischak, H.2    Miethke, T.3    Liptay, S.4    Schmid, R.5    Sparwasser, T.6    Heeg, K.7    Lipford, G.8    Wagner, H.9
  • 28
    • 0036318851 scopus 로고    scopus 로고
    • Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
    • Ahmad-Nejad,P., Hacker,H., Rutz,M., Bauer,S., Vabulas,R. and Wagner,H. (2002) Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur. J. Immunol., 32, 1958-1968.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 1958-1968
    • Ahmad-Nejad, P.1    Hacker, H.2    Rutz, M.3    Bauer, S.4    Vabulas, R.5    Wagner, H.6
  • 29
    • 0035077421 scopus 로고    scopus 로고
    • Preexposure of murine macrophages to CpG oligonucleotide results in a biphasic tumour necrosis factor alpha response to subsequent lipopolysaccharide challenge
    • Crabtree,T., Jin,L., Raymond,D., Pelletier,S., Houlgrave,C., Gleason,T., Pruett,T. and Sawyer,R. (2001) Preexposure of murine macrophages to CpG oligonucleotide results in a biphasic tumour necrosis factor alpha response to subsequent lipopolysaccharide challenge. Infect. Immun., 69, 2123-2129.
    • (2001) Infect. Immun. , vol.69 , pp. 2123-2129
    • Crabtree, T.1    Jin, L.2    Raymond, D.3    Pelletier, S.4    Houlgrave, C.5    Gleason, T.6    Pruett, T.7    Sawyer, R.8
  • 30
    • 0028928953 scopus 로고
    • Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA
    • Egholm,M., Christensen,L., Dueholm,K., Buchardt,O., Coull,J. and Nielsen,P. (1995) Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA. Nucleic Acids Res., 23, 217-222.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 217-222
    • Egholm, M.1    Christensen, L.2    Dueholm, K.3    Buchardt, O.4    Coull, J.5    Nielsen, P.6
  • 32
    • 0035399836 scopus 로고    scopus 로고
    • Novel roles of CpG oligodeoxynucleotides as a leader for the sampling and presentation of CpG-tagged antigen by dendritic cells
    • Shirota,H., Sano,K., Hirasawa,N., Terui,T., Ohuchi,O., Hattori,T., Shirato,K. and Tamura,G. (2001) Novel roles of CpG oligodeoxynucleotides as a leader for the sampling and presentation of CpG-tagged antigen by dendritic cells. J. Immunol., 167, 66-74.
    • (2001) J. Immunol. , vol.167 , pp. 66-74
    • Shirota, H.1    Sano, K.2    Hirasawa, N.3    Terui, T.4    Ohuchi, O.5    Hattori, T.6    Shirato, K.7    Tamura, G.8
  • 34
    • 2642679384 scopus 로고    scopus 로고
    • Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro, enhancement by cotransfection of genes encoding the Th1-biasing cytokines IL-12 and IFN-α
    • Tuting,T., Wilson,C., Martin,D., Kasamon,Y., Rowles,J., Ma,D., Slingluff,C., Wagner,S., van der Bruggen,P., Baar,J., Lotze,M. and Storkus,W. (1998) Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro, enhancement by cotransfection of genes encoding the Th1-biasing cytokines IL-12 and IFN-α. J. Immunol., 160, 1139-1147.
    • (1998) J. Immunol. , vol.160 , pp. 1139-1147
    • Tuting, T.1    Wilson, C.2    Martin, D.3    Kasamon, Y.4    Rowles, J.5    Ma, D.6    Slingluff, C.7    Wagner, S.8    van der Bruggen, P.9    Baar, J.10    Lotze, M.11    Storkus, W.12
  • 35
    • 0032030661 scopus 로고    scopus 로고
    • Differential presentation of the same MHC class I epitopes by fibroblasts and dendritic cells
    • Butz,E. and Bevan,M. (1998) Differential presentation of the same MHC class I epitopes by fibroblasts and dendritic cells. J. Immunol., 160, 2139-2144.
    • (1998) J. Immunol. , vol.160 , pp. 2139-2144
    • Butz, E.1    Bevan, M.2
  • 38
    • 0029963160 scopus 로고    scopus 로고
    • Strand displacement binding of a duplex forming homopurine PNA to a homopyrimidine duplex DNA target
    • Nielsen,P. and Christensen,L. (1996) Strand displacement binding of a duplex forming homopurine PNA to a homopyrimidine duplex DNA target. J. Am. Chem. Soc., 118, 2287-2288.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 2287-2288
    • Nielsen, P.1    Christensen, L.2
  • 39
    • 0034327759 scopus 로고    scopus 로고
    • Enhanced marine macrophage TNF receptor shedding by cytosine-guanine sequences in oligodeoxynucleotides
    • Jin,L., Raymond,D., Crabtree,T., Pelletier,S., Houlgrave,C., Pruett,T. and Sawyer,R. (2000) Enhanced marine macrophage TNF receptor shedding by cytosine-guanine sequences in oligodeoxynucleotides. J. Immunol., 165, 5153-5160.
    • (2000) J. Immunol. , vol.165 , pp. 5153-5160
    • Jin, L.1    Raymond, D.2    Crabtree, T.3    Pelletier, S.4    Houlgrave, C.5    Pruett, T.6    Sawyer, R.7
  • 40
    • 0035877256 scopus 로고    scopus 로고
    • Suppressors of cytokine signalling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs
    • Dalpke,A., Opper,S., Zimmermann,S. and Heeg,K. (2001) Suppressors of cytokine signalling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs. J. Immunol., 166, 7082-7089.
    • (2001) J. Immunol. , vol.166 , pp. 7082-7089
    • Dalpke, A.1    Opper, S.2    Zimmermann, S.3    Heeg, K.4
  • 41
    • 0035337963 scopus 로고    scopus 로고
    • Bacterial DNA and lipopolysaccharide induce synergistic production of TNF-α through a post-transcriptional mechanism
    • Gao,J., Xue,Q., Papasian,J. and Morrison,D. (2001) Bacterial DNA and lipopolysaccharide induce synergistic production of TNF-α through a post-transcriptional mechanism. J. Immunol., 166, 6855-6860.
    • (2001) J. Immunol. , vol.166 , pp. 6855-6860
    • Gao, J.1    Xue, Q.2    Papasian, J.3    Morrison, D.4
  • 42
    • 0035163566 scopus 로고    scopus 로고
    • Lipopolysaccharide and CpG DNA synergize for tumor necrosis factor-α production through activation of NF-κB
    • Yi,A., Yoon,J., Hong,S., Redford,T. and Kreig,A. (2001) Lipopolysaccharide and CpG DNA synergize for tumor necrosis factor-α production through activation of NF-κB. Int. Immunol., 13, 1391-1404.
    • (2001) Int. Immunol. , vol.13 , pp. 1391-1404
    • Yi, A.1    Yoon, J.2    Hong, S.3    Redford, T.4    Kreig, A.5
  • 43
    • 0031684269 scopus 로고    scopus 로고
    • Reduction of antigen expression from DNA vaccines by coadministered oligodeoxynucleotides
    • Weernata,R., Brazalot,M.C., Krieg,A. and Davis,H. (1998) Reduction of antigen expression from DNA vaccines by coadministered oligodeoxynucleotides. Antisense Nucleic Acid Drug Dev., 8, 351-356.
    • (1998) Antisense Nucleic Acid Drug Dev. , vol.8 , pp. 351-356
    • Weernata, R.1    Brazalot, M.C.2    Krieg, A.3    Davis, H.4
  • 44
    • 0034890076 scopus 로고    scopus 로고
    • Modulation of gene-gun-mediated Th2 immunity to hepatitis B surface antigen by bacterial CpG motifs or IL-12
    • Schirmbeck,R. and Reimann,J. (2001) Modulation of gene-gun-mediated Th2 immunity to hepatitis B surface antigen by bacterial CpG motifs or IL-12. Intervirology, 44, 115-123.
    • (2001) Intervirology , vol.44 , pp. 115-123
    • Schirmbeck, R.1    Reimann, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.