메뉴 건너뛰기




Volumn 34, Issue 20, 2006, Pages 5790-5799

Structural diversity of target-specific homopyrimidine peptide nucleic acid-dsDNA complexes

Author keywords

[No Author keywords available]

Indexed keywords

CATION; CYTOSINE; DOUBLE STRANDED DNA; OLIGOMER; PEPTIDE NUCLEIC ACID; PURINE; PYRIDINE; THYMINE;

EID: 33845679853     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl736     Document Type: Article
Times cited : (33)

References (43)
  • 1
    • 23444441147 scopus 로고    scopus 로고
    • Gene targeting using zinc finger nucleases
    • Porteus,M.H. and Carroll,D. (2005) Gene targeting using zinc finger nucleases. Nat. Biotechnol., 8, 967-973.
    • (2005) Nat. Biotechnol. , vol.8 , pp. 967-973
    • Porteus, M.H.1    Carroll, D.2
  • 3
    • 22144484155 scopus 로고    scopus 로고
    • Triplex-forming oligonucleotides as potential tools for modulation of gene expression
    • Rogers,F.A., Lloyd,J.A. and Glazer,P.M. (2005) Triplex-forming oligonucleotides as potential tools for modulation of gene expression. Curr. Med. Chem. Anticancer Agents, 5, 319-326.
    • (2005) Curr. Med. Chem. Anticancer Agents , vol.5 , pp. 319-326
    • Rogers, F.A.1    Lloyd, J.A.2    Glazer, P.M.3
  • 4
    • 10044225983 scopus 로고    scopus 로고
    • Triplex-forming oligonucleotiides - Sequence-specific DNA ligands as tools for gene inhibition and for modulation of DNA-associated functions
    • Besch,R., Giovannangeli,C. and Degitz,K. (2004) Triplex-forming oligonucleotiides - sequence-specific DNA ligands as tools for gene inhibition and for modulation of DNA-associated functions. Curr. Drug Targets, 8, 691-703.
    • (2004) Curr. Drug Targets , vol.8 , pp. 691-703
    • Besch, R.1    Giovannangeli, C.2    Degitz, K.3
  • 5
    • 33845660229 scopus 로고    scopus 로고
    • Peptide nucleic acid targeting of double stranded DNA
    • In Nielsen (ed.), 2nd edn. Horizon Bioscience, Norfolk England
    • Bentin,T., Larsen,H.J. and Nielsen,P.E. (2004) Peptide nucleic acid targeting of double stranded DNA. In Nielsen (ed.), Peptide Nucleic Acids: Protocols and Applications, 2nd edn. Horizon Bioscience, Norfolk England, pp. 107-140.
    • (2004) Peptide Nucleic Acids: Protocols and Applications , pp. 107-140
    • Bentin, T.1    Larsen, H.J.2    Nielsen, P.E.3
  • 6
    • 3042691011 scopus 로고    scopus 로고
    • Recognition of chromosomal DNA by PNAs
    • Kaihatsu,K., Janowski,B.A. and Corey,D.R. (2004) Recognition of chromosomal DNA by PNAs. Chem. Biol., 11, 749-758.
    • (2004) Chem. Biol. , vol.11 , pp. 749-758
    • Kaihatsu, K.1    Janowski, B.A.2    Corey, D.R.3
  • 7
    • 0026341239 scopus 로고
    • Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide
    • Nielsen,P.E., Egholm,M., Berg,R.H. and Buchardt,O. (1991) Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science, 254, 1497-1500.
    • (1991) Science , vol.254 , pp. 1497-1500
    • Nielsen, P.E.1    Egholm, M.2    Berg, R.H.3    Buchardt, O.4
  • 9
    • 0028500559 scopus 로고
    • 2/DNA triplex structure upon binding of PNA to dsDNA by strand displacement
    • 2/DNA triplex structure upon binding of PNA to dsDNA by strand displacement. J. Mol. Recognit., 7, 165-170.
    • (1994) J. Mol. Recognit. , vol.7 , pp. 165-170
    • Nielsen, P.E.1    Egholm, M.2    Buchardt, O.3
  • 12
    • 0028075767 scopus 로고
    • Sequence-specific transcription arrest by peptide nucleic acid bound to the DNA template strand
    • Nielsen,P.E., Egholm,M. and Buchardt,O. (1994) Sequence-specific transcription arrest by peptide nucleic acid bound to the DNA template strand. Gene, 149, 139-145.
    • (1994) Gene , vol.149 , pp. 139-145
    • Nielsen, P.E.1    Egholm, M.2    Buchardt, O.3
  • 13
    • 0028983888 scopus 로고
    • Inhibition of NF-kappa B specific transcriptional activation by PNA strand invasion
    • Vickers,T.A., Griffith,M.C., Ramasmay,K., Risen,L.M. and Freier,S.M. (1995) Inhibition of NF-kappa B specific transcriptional activation by PNA strand invasion. Nucleic Acids Res., 23, 3003-3008.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 3003-3008
    • Vickers, T.A.1    Griffith, M.C.2    Ramasmay, K.3    Risen, L.M.4    Freier, S.M.5
  • 14
    • 9044228030 scopus 로고    scopus 로고
    • Transcription-mediated binding of peptide nucleic acid (PNA) to double-stranded DNA: Sequence-specific suicide transcription
    • Larsen,H.J. and Nielsen,P.E. (1996) Transcription-mediated binding of peptide nucleic acid (PNA) to double-stranded DNA: Sequence-specific suicide transcription. Nucleic Acids Res., 24, 458-463.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 458-463
    • Larsen, H.J.1    Nielsen, P.E.2
  • 15
    • 0142198529 scopus 로고    scopus 로고
    • Transcription activation by a PNA-peptide chimera in a mammalian cell extract
    • Liu,B., Han,Y., Ferdous,A., Corey,D.R. and Kodadek,T. (2003) Transcription activation by a PNA-peptide chimera in a mammalian cell extract. Chem. Biol., 10, 909-916.
    • (2003) Chem. Biol. , vol.10 , pp. 909-916
    • Liu, B.1    Han, Y.2    Ferdous, A.3    Corey, D.R.4    Kodadek, T.5
  • 16
    • 0028175775 scopus 로고
    • Peptide nucleic acid-DNA strand displacement loops as artificial transcription promoters
    • Møllegaard,N.E., Buchardt,O., Egholm,M. and Nielsen,P.E. (1994) Peptide nucleic acid-DNA strand displacement loops as artificial transcription promoters. Proc. Natl Acad. Sci. USA, 91, 3892-3895.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 3892-3895
    • Møllegaard, N.E.1    Buchardt, O.2    Egholm, M.3    Nielsen, P.E.4
  • 20
    • 0037837659 scopus 로고    scopus 로고
    • Superior duplex DNA strand invasion by acridine conjugated peptide nucleic acids
    • Bentin,T. and Nielsen,P.E. (2003) Superior duplex DNA strand invasion by acridine conjugated peptide nucleic acids. J. Am. Chem. Soc., 125, 6378-6379.
    • (2003) J. Am. Chem. Soc. , vol.125 , pp. 6378-6379
    • Bentin, T.1    Nielsen, P.E.2
  • 21
    • 0035896022 scopus 로고    scopus 로고
    • Structural isomers of bis-PNA bound to a target in duplex DNA
    • Hansen,G.I., Bentin,T., Larsen,H.J. and Nielsen,P.E. (2001) Structural isomers of bis-PNA bound to a target in duplex DNA. J. Mol. Biol., 307, 67-74.
    • (2001) J. Mol. Biol. , vol.307 , pp. 67-74
    • Hansen, G.I.1    Bentin, T.2    Larsen, H.J.3    Nielsen, P.E.4
  • 22
    • 0034718453 scopus 로고    scopus 로고
    • Effect of temperature and ionic strength on the dissociation kinetics and lifetime of PNA-DNA triplexes
    • Kosaganov,Y.N., Stetsenko,D.A., Lubyako,E.N., Kvito,N.P., Lazurkin,Y.S. and Nielsen,P.E. (2000) Effect of temperature and ionic strength on the dissociation kinetics and lifetime of PNA-DNA triplexes. Biochemistry, 39, 11742-11747.
    • (2000) Biochemistry , vol.39 , pp. 11742-11747
    • Kosaganov, Y.N.1    Stetsenko, D.A.2    Lubyako, E.N.3    Kvito, N.P.4    Lazurkin, Y.S.5    Nielsen, P.E.6
  • 24
    • 0032518182 scopus 로고    scopus 로고
    • Kinetic sequence discrimination of cationic bis-PNAs upon targeting of double-stranded DNA
    • Kuhn,H., Demidov,V.V., Frank-Kamenetskii,M.D. and Nielsen,P.E. (1998) Kinetic sequence discrimination of cationic bis-PNAs upon targeting of double-stranded DNA. Nucleic Acids Res., 26, 582-587.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 582-587
    • Kuhn, H.1    Demidov, V.V.2    Frank-Kamenetskii, M.D.3    Nielsen, P.E.4
  • 25
    • 0033548529 scopus 로고    scopus 로고
    • An experimental study of mechanism and specificity of peptide nucleic acid (PNA) binding to duplex DNA
    • Kuhn,H., Demidov,V.V., Nielsen,P.E. and Frank-Kamenetskii,M.D. (1999) An experimental study of mechanism and specificity of peptide nucleic acid (PNA) binding to duplex DNA. J. Mol. Biol., 286, 1337-1345.
    • (1999) J. Mol. Biol. , vol.286 , pp. 1337-1345
    • Kuhn, H.1    Demidov, V.V.2    Nielsen, P.E.3    Frank-Kamenetskii, M.D.4
  • 26
    • 31544461288 scopus 로고    scopus 로고
    • PNA-nitrogen mustard conjugates are effective supressors of HER-2/neu and biological tools for recognition of PNA/DNA interactions
    • Zhilina,Z.V., Ziemba,A.J., Nielsen,P.E. and Ebbinghaus,S.W. (2006) PNA-nitrogen mustard conjugates are effective supressors of HER-2/neu and biological tools for recognition of PNA/DNA interactions. Bioconjug. Chem., 17, 214-222.
    • (2006) Bioconjug. Chem. , vol.17 , pp. 214-222
    • Zhilina, Z.V.1    Ziemba, A.J.2    Nielsen, P.E.3    Ebbinghaus, S.W.4
  • 31
    • 0019332029 scopus 로고
    • Pyrimidine-specific chemical reactions useful for DNA sequencing
    • Rubin,C.M. and Schmid,C.W. (1988) Pyrimidine-specific chemical reactions useful for DNA sequencing. Nucleic Acids Res., 8, 4613-4619.
    • (1988) Nucleic Acids Res. , vol.8 , pp. 4613-4619
    • Rubin, C.M.1    Schmid, C.W.2
  • 33
    • 0345445891 scopus 로고    scopus 로고
    • Combined triplex/duplex invasion of double-stranded DNA by 'tail-clamp' peptide nucleic acid
    • Bentin,T., Larsen,H.J. and Nielsen,P.E. (2003) Combined triplex/duplex invasion of double-stranded DNA by 'tail-clamp' peptide nucleic acid. Biochemistry, 42, 13987-13995.
    • (2003) Biochemistry , vol.42 , pp. 13987-13995
    • Bentin, T.1    Larsen, H.J.2    Nielsen, P.E.3
  • 35
    • 0030035244 scopus 로고    scopus 로고
    • Enhanced peptide nucleic acid binding to supercoiled DNA: Possible implications for DNA 'breathing' dynamics
    • Bentin,T. and Nielsen,P.E.(1996) Enhanced peptide nucleic acid binding to supercoiled DNA: Possible implications for DNA 'breathing' dynamics. Biochemistry, 35, 8863-8869.
    • (1996) Biochemistry , vol.35 , pp. 8863-8869
    • Bentin, T.1    Nielsen, P.E.2
  • 36
    • 0032007456 scopus 로고    scopus 로고
    • Cooperative strand displacement by peptide nucleic acid (PNA)
    • Kurakin,A., Larsen,H.J. and Nielsen,P.E. (1998) Cooperative strand displacement by peptide nucleic acid (PNA). Chem. Biol., 5, 81-89.
    • (1998) Chem. Biol. , vol.5 , pp. 81-89
    • Kurakin, A.1    Larsen, H.J.2    Nielsen, P.E.3
  • 37
    • 0000385944 scopus 로고    scopus 로고
    • Design of new anti-cancer agents based on topoisomerase poisons targeted to specific DNA sequences
    • Arimondo,P.B. and Helene,C. (2001) Design of new anti-cancer agents based on topoisomerase poisons targeted to specific DNA sequences. Curr. Med. Chem. Anticancer Agents, 3, 219-235.
    • (2001) Curr. Med. Chem. Anticancer Agents , vol.3 , pp. 219-235
    • Arimondo, P.B.1    Helene, C.2
  • 38
    • 0023619361 scopus 로고
    • Sequence-specific cleavage of double helical DNA by triple helix formation
    • Moser,H.E. and Dervan,P.B. (1987) Sequence-specific cleavage of double helical DNA by triple helix formation. Science, 238, 645-650.
    • (1987) Science , vol.238 , pp. 645-650
    • Moser, H.E.1    Dervan, P.B.2
  • 39
    • 12344301295 scopus 로고    scopus 로고
    • Extended target sequence specificity of PNA-minor-groove binder conjugates
    • Nielsen,P.E., Frederiksen,K. and Behrens,C. (2005) Extended target sequence specificity of PNA-minor-groove binder conjugates. Chembiochem, 6, 66-68.
    • (2005) Chembiochem , vol.6 , pp. 66-68
    • Nielsen, P.E.1    Frederiksen, K.2    Behrens, C.3
  • 40
    • 0442323636 scopus 로고    scopus 로고
    • Frank-Kamenetskii,M.D. Two sides of the coin: Affinity and specificity of nucleic acid interactions
    • Demidov,V.V. and Frank-Kamenetskii,M.D. (2004) Two sides of the coin: affinity and specificity of nucleic acid interactions. Trends Biochem. Sci., 29, 62-71.
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 62-71
    • Demidov, V.V.1
  • 42
    • 16344371778 scopus 로고    scopus 로고
    • RNA and protein folding: Common themes and variations
    • Thirumalai,D. and Hyeon,C. (2005) RNA and protein folding: Common themes and variations. Biochemistry, 44, 4957-4970.
    • (2005) Biochemistry , vol.44 , pp. 4957-4970
    • Thirumalai, D.1    Hyeon, C.2
  • 43
    • 0030834244 scopus 로고    scopus 로고
    • Extended DNA-recognition repertoire of peptide nucleic acid (PNA): PNA-dsDNA triplex formed with cytosine-rich homopyrimidine PNA
    • Wittung,P., Nielsen,P. and Norden,B. (1997) Extended DNA-recognition repertoire of peptide nucleic acid (PNA): PNA-dsDNA triplex formed with cytosine-rich homopyrimidine PNA. Biochemistry, 36, 7973-7979.
    • (1997) Biochemistry , vol.36 , pp. 7973-7979
    • Wittung, P.1    Nielsen, P.2    Norden, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.