Excitotoxicity through NMDA receptors mediates cerebellar granule neuron apoptosis induced by prion protein 90-231 fragment

Neurotoxicity Research

Volumn 23, Issue 4, 2013, Pages 301-314

  Thellung, Stefano ^a   Gatta, Elena ^b   Pellistri, Francesca ^b   Corsaro, Alessandro ^a   Villa, Valentina ^a   Vassalli, Massimo ^c   Robello, Mauro ^b   Florio, Tullio ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c CNR   (Italy)

Author keywords

Apoptosis; Calcium; Cerebellar neurons; NMDA receptor; Prion; PrP90 231

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMINO ACID; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; AMYLOID; CALCIUM ION; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR ANTAGONIST; LIPOCORTIN 5; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PRION PROTEIN; PRION PROTEIN 90 231 FRAGMENT; PROTEINASE K; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING ASSAY; CALCIUM HOMEOSTASIS; CELL NUCLEUS; CEREBELLUM; CONTROLLED STUDY; EXCITOTOXICITY; GRANULE CELL; HYDROPHOBICITY; IN VITRO STUDY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STRUCTURE; RAT; TEMPERATURE; TOXICITY;

ANIMALS; APOPTOSIS; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; NEURONS; PEPTIDE FRAGMENTS; PRIONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE;

RATTUS;

EID: 84876287105     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-012-9340-9     Document Type: Article

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