Amyloid fibrils of mammalian prion protein are highly toxic to cultured cells and primary neurons

Journal of Biological Chemistry

Volumn 281, Issue 19, 2006, Pages 13828-13836

  Novitskaya, Vera ^a,d   Bocharova, Olga V ^a,e   Bronstein, Igor ^c   Baskakov, Ilia V ^a,b  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^e SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; INSULIN; NEUROLOGY; PROTEINS; TOXICITY;

AMYLOID FIBRILS; APOPTOTIC CELLS; CELL DEATH; OLIGOMERIC SPECIES;

BIODIVERSITY;

INSULIN; PRION PROTEIN; RECOMBINANT PROTEIN; SMALL INTERFERING RNA;

ALPHA HELIX; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CEREBELLUM; CONTROLLED STUDY; DOWN REGULATION; HIPPOCAMPUS; HUMAN; HUMAN CELL; MOUSE; MUSCLE FIBRIL; NERVE CELL; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION;

AMYLOID; ANIMALS; APOPTOSIS; CELLS, CULTURED; HUMANS; INSULIN; MICE; NEURONS; PRIONS; PROTEIN ISOFORMS; RATS; RATS, WISTAR;

EPICOCCUM; MAMMALIAN PRION;

EID: 33744961169     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M511174200     Document Type: Article

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