In vivo and in vitro neurotoxicity of the human prion protein (PrP) fragment P118-135 independently of PrP expression

Journal of Neuroscience

Volumn 23, Issue 2, 2003, Pages 462-469

  Chabry, Joëlle ^a   Ratsimanohatra, Christiane ^b   Sponne, Isabelle ^c   Elena, Pierre Paul ^b   Vincent, Jean Pierre ^a   Pillot, Thierry ^c  

^a CNRS   (France)

^b Iris Pharma   (France)

^c INSERM   (France)

Author keywords

Apoptosis; Caspase activities; Electroretinogram; In vivo; Prion peptide; Retina

Indexed keywords

CASPASE; DNA FRAGMENT; FUSOGENIC PEPTIDE P118 135; PRION PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN SPONGIOSIS; CELL DEATH; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; CYTOTOXICITY; ELECTRIC ACTIVITY; ELECTRORETINOGRAM; ENZYME ACTIVATION; KNOCKOUT GENE; KNOCKOUT MOUSE; MALE; MEMBRANE DEPOLARIZATION; MOUSE; NERVE CELL CULTURE; NERVE CONDUCTION; NERVE DEGENERATION; NEUROFILAMENT; NEUROTOXICITY; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; RETINA; RETINA NERVE CELL;

EID: 0037439629     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-02-00462.2003     Document Type: Article

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