Aβ neurotoxicity depends on interactions between copper ions, prion protein,and N-methyl-D-aspartate receptors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 5, 2012, Pages 1737-1742

  You, Haitao ^a   Tsutsui, Shigeki ^a   Hameed, Shahid ^a   Kannanayakal, Thomas J ^a   Chen, Lina ^a   Xia, Peng ^b   Engbers, Jordan D T ^a   Lipton, Stuart A ^b   Stys, Peter K ^a   Zamponi, Gerald W ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b BURNHAM INSTITUTE   (United States)

Author keywords

5XFAD mouse; A oligomer; Alzheimer's disease; Cu; NMDA receptor

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; COPPER ION; GLYCINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PRION PROTEIN;

ALLOSTERISM; ANIMAL EXPERIMENT; ARTICLE; CELL SURFACE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HIPPOCAMPUS; MOLECULAR INTERACTION; MOLECULAR MIMICRY; NERVE CELL LESION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STEADY STATE; SYNAPSE;

AMYLOID BETA-PEPTIDES; ANIMALS; CELLS, CULTURED; COPPER; FEMALE; KINETICS; PEPTIDE FRAGMENTS; PREGNANCY; PRPC PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE;

RODENTIA;

EID: 84863116075     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1110789109     Document Type: Article

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