Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition

Chemical Research in Toxicology

Volumn 26, Issue 4, 2013, Pages 517-528

  Shimada, Tsutomu ^a,b   Kim, Donghak ^a,c   Murayama, Norie ^e   Tanaka, Katsuhiro ^b   Takenaka, Shigeo ^b   Nagy, Leslie D ^a   Folkman, Lindsay M ^a   Foroozesh, Maryam K ^d   Komori, Masayuki ^b   Yamazaki, Hiroshi ^e   Guengerich, F Peter ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Osaka Prefecture University   (Japan)

^c Konkuk University   (South Korea)

^d XAVIER UNIVERSITY OF LOUISIANA   (United States)

^e SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 HYDROXYPYRENE; 1 NITROPYRENE; 7 HYDROXYFLAVONE; ACENAPHTHYLENE; BIPHENYL; CHRYSIN; CYTOCHROME P450 1B1; CYTOCHROME P450 2A; CYTOCHROME P450 2A13; CYTOCHROME P450 2A6; FLAVONE; FLUORANTHENE; GALANGIN; NAPHTHALENE; PHENANTHRENE; PYRENE; TETRACHLOROBIPHENYL; UNCLASSIFIED DRUG;

ARTICLE; BIOMEDICINE; ENZYME INHIBITION; HYDROXYLATION; NONHUMAN;

ARYL HYDROCARBON HYDROXYLASES; BINDING SITES; CARCINOGENS; ENVIRONMENTAL POLLUTANTS; ESCHERICHIA COLI; FLAVONOIDS; HUMANS; MOLECULAR DOCKING SIMULATION; POLYCYCLIC HYDROCARBONS, AROMATIC;

EID: 84876255651     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx300492j     Document Type: Article

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