Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen

Nature Structural and Molecular Biology

Volumn 12, Issue 9, 2005, Pages 822-823

  Yano, Jason K ^a   Hsu, Mei Hui ^a   Griffin, Keith J ^a   Stout, C David ^a   Johnson, Eric F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; COUMARIN; METHOXSALEN; MUTAGENIC AGENT; COUMARIN 7 HYDROXYLASE; COUMARIN 7-HYDROXYLASE; COUMARIN DERIVATIVE; MIXED FUNCTION OXIDASE; UNSPECIFIC MONOOXYGENASE;

ARTICLE; CANCER; DETOXIFICATION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; GENE ACTIVATION; HUMAN; HYDROGEN BOND; HYDROPHILICITY; MUTAGENESIS; PRIORITY JOURNAL; SMOKING CESSATION; STRUCTURE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; METABOLISM; MICROSOME; PROTEIN TERTIARY STRUCTURE;

NICOTIANA TABACUM;

ARYL HYDROCARBON HYDROXYLASES; COUMARINS; HUMANS; METHOXSALEN; MICROSOMES; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY;

EID: 26944462419     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb971     Document Type: Article

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