Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans

Archives of Toxicology

Volumn 71, Issue 6, 1997, Pages 401-408

  Shimada, Tsutomu ^a   Mimura, Mayumi ^a   Inoue, Kiyoshi ^a   Nakamura, Sei Ichi ^a   Oda, Hajime ^a   Ohmori, Shigeru ^b   Yamazaki, Hiroshi ^a  

^a OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^b CHIBA UNIVERSITY HOSPITAL   (Japan)

Author keywords

CYP; Cytochrome P450; Drug metabolism; Liver microsomes; Species

Indexed keywords

ANILINE; BENZPHETAMINE; BUFURALOL; COUMARIN; CYTOCHROME P450; ERYTHROMYCIN; ETHYLMORPHINE; MEPHENYTOIN; NIFEDIPINE; PENTOXYRESORUFIN; PHENACETIN; PHENYTOIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; DRUG OXIDATION; ENZYME ACTIVITY; GUINEA PIG; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; LIVER METABOLISM; LIVER MICROSOME; MONKEY; NONHUMAN; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE;

ADRENERGIC BETA-ANTAGONISTS; ANILINE COMPOUNDS; ANIMALS; ANTINEOPLASTIC AGENTS; BENZPHETAMINE; CARCINOGENS; COUMARINS; CYTOCHROME P-450 ENZYME SYSTEM; DOGS; ERYTHROMYCIN; ETHANOLAMINES; ETHYLMORPHINE; GUINEA PIGS; HUMANS; MACACA FASCICULARIS; MEPHENYTOIN; MICROSOMES, LIVER; NIFEDIPINE; OXAZINES; OXIDATION-REDUCTION; PHENACETIN; PHENYTOIN; RATS; SPECIES SPECIFICITY;

EID: 0030959377     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050403     Document Type: Article

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