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Volumn 66, Issue 3, 2006, Pages 1401-1408

Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity of nonhomologous end-joining

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; CHECKPOINT KINASE 2; DOUBLE STRANDED DNA;

EID: 32944477537     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-3278     Document Type: Article
Times cited : (98)

References (46)
  • 1
    • 0035289717 scopus 로고    scopus 로고
    • Chromosomal stability and the DNA double-stranded break connection
    • van Gent DC HJ, Kanaar R. Chromosomal stability and the DNA double-stranded break connection. Nat Rev Genet 2001;2:196-206.
    • (2001) Nat Rev Genet , vol.2 , pp. 196-206
    • Van Gent, D.C.H.J.1    Kanaar, R.2
  • 2
    • 0035093737 scopus 로고    scopus 로고
    • DNA double-strand breaks: Signaling, repair and the cancer connection
    • Khanna K, Jackson SP. DNA double-strand breaks: signaling, repair and the cancer connection. Nat Genet 2001;27;247-54.
    • (2001) Nat Genet , vol.27 , pp. 247-254
    • Khanna, K.1    Jackson, S.P.2
  • 3
    • 0034951142 scopus 로고    scopus 로고
    • Double-strand-break-induced homologous recombination in mammalian cells
    • Johnson RD, Jasin M. Double-strand-break-induced homologous recombination in mammalian cells. Biochem Soc Trans 2001;29:196-201.
    • (2001) Biochem Soc Trans , vol.29 , pp. 196-201
    • Johnson, R.D.1    Jasin, M.2
  • 4
    • 0042839614 scopus 로고    scopus 로고
    • Mechanism and regulation of human non-homologous DNA end-joining
    • Lieber MR, Ma Y, Pannicke U, Schwarz K. Mechanism and regulation of human non-homologous DNA end-joining. Nat Rev Mol Cell Biol 2003;4:712-20.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 712-720
    • Lieber, M.R.1    Ma, Y.2    Pannicke, U.3    Schwarz, K.4
  • 5
    • 2942525595 scopus 로고    scopus 로고
    • Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells
    • Guirouilh-Barbat J, Huck S, Bertrand P, et al. Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells. Mol Cell 2004;14:611-23.
    • (2004) Mol Cell , vol.14 , pp. 611-623
    • Guirouilh-Barbat, J.1    Huck, S.2    Bertrand, P.3
  • 6
    • 0347510576 scopus 로고    scopus 로고
    • End-joining of blunt DNA double-strand breaks in mammalian fibroblasts is precise and requires DNA-PK and XRCC4
    • van Heemst D, Brugmans L, Verkaik NS, van Gent DC. End-joining of blunt DNA double-strand breaks in mammalian fibroblasts is precise and requires DNA-PK and XRCC4. DNA Repair 2004;3:43-50.
    • (2004) DNA Repair , vol.3 , pp. 43-50
    • Van Heemst, D.1    Brugmans, L.2    Verkaik, N.S.3    Van Gent, D.C.4
  • 7
    • 0035928799 scopus 로고    scopus 로고
    • New complexities for BRCA1 and BRCA2
    • Kerr P, Ashworth A. New complexities for BRCA1 and BRCA2. Curr Biol 2001;11:R668-76.
    • (2001) Curr Biol , vol.11
    • Kerr, P.1    Ashworth, A.2
  • 8
    • 0037169354 scopus 로고    scopus 로고
    • Cancer susceptibility and the functions of BRCA1 and BRCA2
    • Venkitaraman AR. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell Growth Differ 2002;108:171-82.
    • (2002) Cell Growth Differ , vol.108 , pp. 171-182
    • Venkitaraman, A.R.1
  • 9
    • 0346095320 scopus 로고    scopus 로고
    • Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair
    • Zhang J, Willers H, Feng Z, et al. Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair. Mol Cell Biol 2004;24:708-18.
    • (2004) Mol Cell Biol , vol.24 , pp. 708-718
    • Zhang, J.1    Willers, H.2    Feng, Z.3
  • 10
    • 0031472370 scopus 로고    scopus 로고
    • Association of BRCA1 with Rad51 in mitotic and meiotic cells
    • Scully R, Chen J, Plug A, et al. Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell 1997;88:265-75.
    • (1997) Cell , vol.88 , pp. 265-275
    • Scully, R.1    Chen, J.2    Plug, A.3
  • 11
    • 0033590171 scopus 로고    scopus 로고
    • BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a Brca1 transgene
    • Snouwaert JN, Gowen LC, Latour AM, et al. BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a Brca1 transgene. Oncogene 1999;18:7900-7.
    • (1999) Oncogene , vol.18 , pp. 7900-7907
    • Snouwaert, J.N.1    Gowen, L.C.2    Latour, A.M.3
  • 12
    • 0037506012 scopus 로고    scopus 로고
    • Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: A multigenic study on cancer susceptibility
    • Fu Y-P, Yu J-C, Cheng T-C, et al. Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: a multigenic study on cancer susceptibility. Cancer Res 2003;63:2440-6.
    • (2003) Cancer Res , vol.63 , pp. 2440-2446
    • Fu, Y.-P.1    Yu, J.-C.2    Cheng, T.-C.3
  • 13
    • 3142695504 scopus 로고    scopus 로고
    • Breast cancer risk and the DNA double-strand break end-joining capacity of nonhomologous end-joining genes are affected by BRCA1
    • Bau D-T, Fu Y-P, Chen S-T, et al. Breast cancer risk and the DNA double-strand break end-joining capacity of nonhomologous end-joining genes are affected by BRCA1 Cancer Res 2004;64:5013-9.
    • (2004) Cancer Res , vol.64 , pp. 5013-5019
    • Bau, D.-T.1    Fu, Y.-P.2    Chen, S.-T.3
  • 15
    • 0037099520 scopus 로고    scopus 로고
    • Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts
    • Zhong Q, Boyer TG, Chen P-L, Lee W-H. Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts. Cancer Res 2002;62:3966-70.
    • (2002) Cancer Res , vol.62 , pp. 3966-3970
    • Zhong, Q.1    Boyer, T.G.2    Chen, P.-L.3    Lee, W.-H.4
  • 16
    • 0037047387 scopus 로고    scopus 로고
    • BRCA1 facilitates microhomology-mediated end joining of DNA double strand breaks
    • Zhong Q, Chen C-F, Chen P-L, Lee W-H. BRCA1 facilitates microhomology-mediated end joining of DNA double strand breaks. J Biol Chem 2002;277:28641-7.
    • (2002) J Biol Chem , vol.277 , pp. 28641-28647
    • Zhong, Q.1    Chen, C.-F.2    Chen, P.-L.3    Lee, W.-H.4
  • 17
    • 85047697866 scopus 로고    scopus 로고
    • A single mutated BRCA1 allele leads to impaired fidelity of double strand break end-joining
    • Baldeyron C, Jacquemin E, Smith J, et al. A single mutated BRCA1 allele leads to impaired fidelity of double strand break end-joining. Oncogene 2002;21:1401-10.
    • (2002) Oncogene , vol.21 , pp. 1401-1410
    • Baldeyron, C.1    Jacquemin, E.2    Smith, J.3
  • 18
    • 0035136283 scopus 로고    scopus 로고
    • Nonhomologous end-joining of ionizing radiation-induced dna double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2
    • Wang H, Zeng Z-C, Bui T-A, et al. Nonhomologous end-joining of ionizing radiation-induced dna double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2. Cancer Res 2001;61:270-7.
    • (2001) Cancer Res , vol.61 , pp. 270-277
    • Wang, H.1    Zeng, Z.-C.2    Bui, T.-A.3
  • 20
    • 0242468933 scopus 로고    scopus 로고
    • Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences
    • Ma JL, Kim EM, Haber JE, Lee SE. Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences. Mol Cell Biol 2003;23:8820-8.
    • (2003) Mol Cell Biol , vol.23 , pp. 8820-8828
    • Ma, J.L.1    Kim, E.M.2    Haber, J.E.3    Lee, S.E.4
  • 21
    • 0038137214 scopus 로고    scopus 로고
    • Impact of DNA ligase IV on the fidelity of end joining in human cells
    • Smith J, Riballo E, Kysela B, et al. Impact of DNA ligase IV on the fidelity of end joining in human cells. Nucleic Acids Res 2003;31:2157-67.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2157-2167
    • Smith, J.1    Riballo, E.2    Kysela, B.3
  • 23
    • 2642570858 scopus 로고    scopus 로고
    • Mechanisms of DNA double strand break repair and chromosome aberration formation
    • Iliakis G, Wang H, Perrault AB, et al. Mechanisms of DNA double strand break repair and chromosome aberration formation. Cytogenet Genome Res 2004;104:14-20.
    • (2004) Cytogenet Genome Res , vol.104 , pp. 14-20
    • Iliakis, G.1    Wang, H.2    Perrault, A.B.3
  • 24
    • 0034162719 scopus 로고    scopus 로고
    • DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus
    • DiBiase SJ, Zeng ZC, Chen R, Hyslop T, Curran WJ, Jr., Iliakis G. DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus. Cancer Res 2000;60:1245-53.
    • (2000) Cancer Res , vol.60 , pp. 1245-1253
    • Dibiase, S.J.1    Zeng, Z.C.2    Chen, R.3    Hyslop, T.4    Curran Jr., W.J.5    Iliakis, G.6
  • 25
    • 0034234487 scopus 로고    scopus 로고
    • DNA double-strand break repair in cell-free extracts from Ku80-deficient cells, implication for Ku serving as an alignment factor in non-homologous DNA end-joining
    • Feldmann E, Schmiemann V, Goedecke W, Reichenberger S, Pfeiffer P. DNA double-strand break repair in cell-free extracts from Ku80-deficient cells, implication for Ku serving as an alignment factor in non-homologous DNA end-joining. Nucleic Acids Res 2000;28:2585-96.
    • (2000) Nucleic Acids Res , vol.28 , pp. 2585-2596
    • Feldmann, E.1    Schmiemann, V.2    Goedecke, W.3    Reichenberger, S.4    Pfeiffer, P.5
  • 26
    • 0029791694 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways
    • Boulton SJ, Jackson SP. Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J 1996;15:5093-103.
    • (1996) EMBO J , vol.15 , pp. 5093-5103
    • Boulton, S.J.1    Jackson, S.P.2
  • 27
    • 0033618621 scopus 로고    scopus 로고
    • Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response
    • Zhong Q, Chen CF, Li S, et al. Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response. Science 1999;285:747-50.
    • (1999) Science , vol.285 , pp. 747-750
    • Zhong, Q.1    Chen, C.F.2    Li, S.3
  • 28
    • 0038496703 scopus 로고    scopus 로고
    • Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control
    • Lou Z, Chini CCS, Minter-Dykhouse K, Chen J. Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control. J Biol Chem 2003;278:13599-602.
    • (2003) J Biol Chem , vol.278 , pp. 13599-13602
    • Lou, Z.1    Chini, C.C.S.2    Minter-Dykhouse, K.3    Chen, J.4
  • 29
    • 0033527717 scopus 로고    scopus 로고
    • Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
    • Cortez D, Wang Y, Qin J, Elledge SJ. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks [see comments]. Science 1999;286:1162-6.
    • (1999) Science , vol.286 , pp. 1162-1166
    • Cortez, D.1    Wang, Y.2    Qin, J.3    Elledge, S.J.4
  • 30
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • Zhou BBS, Elledge SJ. The DNA damage response: putting checkpoints in perspective [review]. Nature 2000;408:433-9.
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.S.1    Elledge, S.J.2
  • 31
    • 0034624718 scopus 로고    scopus 로고
    • hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response
    • Lee JS, Collins KM, Brown AL, Lee CH, Chung JH. hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature 2000;404:201-4.
    • (2000) Nature , vol.404 , pp. 201-204
    • Lee, J.S.1    Collins, K.M.2    Brown, A.L.3    Lee, C.H.4    Chung, J.H.5
  • 32
    • 0034999997 scopus 로고    scopus 로고
    • A comparison of vertical force and temporal parameters produced by an in-shoe pressure measuring system and a force platform
    • Barnett S, Cunningham JL, West S. A comparison of vertical force and temporal parameters produced by an in-shoe pressure measuring system and a force platform. Clin Biomech 2001;16:353-7.
    • (2001) Clin Biomech , vol.16 , pp. 353-357
    • Barnett, S.1    Cunningham, J.L.2    West, S.3
  • 33
    • 18544389716 scopus 로고    scopus 로고
    • Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations
    • Meijers-Heijboer H, van den Ouweland A, Klijn J, et al. Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nature Gen 2002;31:55-9.
    • (2002) Nature Gen , vol.31 , pp. 55-59
    • Meijers-Heijboer, H.1    Van Den Ouweland, A.2    Klijn, J.3
  • 34
    • 0036847998 scopus 로고    scopus 로고
    • PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2
    • Yang S, Kuo C. Bisi JE, Kim MK. PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2. Nat Cell Biol 2002;4:865-70.
    • (2002) Nat Cell Biol , vol.4 , pp. 865-870
    • Yang, S.1    Kuo, C.2    Bisi, J.E.3    Kim, M.K.4
  • 35
    • 3843139313 scopus 로고    scopus 로고
    • Nuclear scaffold/matrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome
    • Jenke ACW, Stehle IM, Herrmann F, et al. Nuclear scaffold/matrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome. Proc Natl Acad Sci U S A 2004;101:11322-7.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 11322-11327
    • Jenke, A.C.W.1    Stehle, I.M.2    Herrmann, F.3
  • 36
    • 0035164722 scopus 로고    scopus 로고
    • Homologous recombination in extrachromo somal plasmid substrates is not suppressed by p53
    • Willers H, McCarthy EE, Hubbe P, Dahm-Daphi J, Powell SN. Homologous recombination in extrachromo somal plasmid substrates is not suppressed by p53. Carcinogenesis 2001;22:1757-63.
    • (2001) Carcinogenesis , vol.22 , pp. 1757-1763
    • Willers, H.1    McCarthy, E.E.2    Hubbe, P.3    Dahm-Daphi, J.4    Powell, S.N.5
  • 37
    • 0027512522 scopus 로고
    • Characterization of the DNA double strand break repair defect in scid mice
    • Chang C, Biedermann KA, Mezzina M, Brown JM. Characterization of the DNA double strand break repair defect in scid mice. Cancer Res 1993;53:1244-8.
    • (1993) Cancer Res , vol.53 , pp. 1244-1248
    • Chang, C.1    Biedermann, K.A.2    Mezzina, M.3    Brown, J.M.4
  • 39
    • 0036206462 scopus 로고    scopus 로고
    • Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells
    • Verkaik NS, Esveldt-van Lange RE, van Heemst D, et al. Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells. Eur J Immunol 2002;32:701-9.
    • (2002) Eur J Immunol , vol.32 , pp. 701-709
    • Verkaik, N.S.1    Esveldt-Van Lange, R.E.2    Van Heemst, D.3
  • 41
    • 12444254801 scopus 로고    scopus 로고
    • Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage
    • Lee JH, Xu B, Lee C-H, et al. Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage. Mol Cancer Res 2003;1:674-81.
    • (2003) Mol Cancer Res , vol.1 , pp. 674-681
    • Lee, J.H.1    Xu, B.2    Lee, C.-H.3
  • 43
    • 0034713466 scopus 로고    scopus 로고
    • ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response
    • Wu X, Ranganathan V, Weisman DS, et al. ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature 2000;405:477-82.
    • (2000) Nature , vol.405 , pp. 477-482
    • Wu, X.1    Ranganathan, V.2    Weisman, D.S.3
  • 44
    • 32944459979 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutated and checkpoint kinase-2 regulate BRCA1 to promote the fidelity of DNA end-joining
    • In press
    • Wang H-C, Chou W-C, Shieh S-Y, and Shen C-Y. Ataxia telangiectasia mutated and checkpoint kinase-2 regulate BRCA1 to promote the fidelity of DNA end-joining. Cancer Res. In press 2006.
    • (2006) Cancer Res
    • Wang, H.-C.1    Chou, W.-C.2    Shieh, S.-Y.3    Shen, C.-Y.4
  • 45
    • 0034612307 scopus 로고    scopus 로고
    • A mechanistic basis for Mre11-directed DNA joining at microhomologies
    • Paull TT, Gellert M. A mechanistic basis for Mre11-directed DNA joining at microhomologies. Proc Natl Acad Sci U S A 2000;97:6409-14.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 6409-6414
    • Paull, T.T.1    Gellert, M.2
  • 46
    • 0030850047 scopus 로고    scopus 로고
    • Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
    • Scully R, Chen J, Ochs RL, et al. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 1997;90:425-35.
    • (1997) Cell , vol.90 , pp. 425-435
    • Scully, R.1    Chen, J.2    Ochs, R.L.3


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