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Volumn 253, Issue 1, 2013, Pages 185-197

A daunting task: Manipulating leukocyte function with RNAi

Author keywords

Integrins; Leukocytes; Liposomes; Nanoparticles; RNAi

Indexed keywords

APTAMER; ATELOCOLLAGEN; BETA7 INTEGRIN; CD18 ANTIGEN; CD7 ANTIGEN; CHOLINERGIC RECEPTOR; CLAUDIN; CYCLIN D1; CYCLIN DEPENDENT KINASE; DNA; DOUBLE STRANDED RNA; EFALIZUMAB; GAMMA INTERFERON; GLYCOPROTEIN GP 160; HISTONE ACETYLTRANSFERASE; HYALURONIC ACID; INTEGRIN; INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; LIPOPOLYSACCHARIDE; NATALIZUMAB; OCCLUDIN; PROTAMINE; RNA; SMALL INTERFERING RNA; SOLID LIPID NANOPARTICLE; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; VIRUS ANTIBODY;

EID: 84875801524     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12044     Document Type: Review
Times cited : (52)

References (124)
  • 1
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001;411:494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 2
    • 26944498261 scopus 로고    scopus 로고
    • Approaches for chemically synthesized siRNA and vector-mediated RNAi
    • Amarzguioui M, Rossi JJ, Kim D. Approaches for chemically synthesized siRNA and vector-mediated RNAi. FEBS Lett 2005;579:5974-5981.
    • (2005) FEBS Lett , vol.579 , pp. 5974-5981
    • Amarzguioui, M.1    Rossi, J.J.2    Kim, D.3
  • 3
    • 33746228119 scopus 로고    scopus 로고
    • Knocking down disease with siRNAs
    • Dykxhoorn DM, Lieberman J. Knocking down disease with siRNAs. Cell 2006;126:231-235.
    • (2006) Cell , vol.126 , pp. 231-235
    • Dykxhoorn, D.M.1    Lieberman, J.2
  • 4
    • 23044463005 scopus 로고    scopus 로고
    • RNA interference in biology and disease
    • Sledz CA, Williams BR. RNA interference in biology and disease. Blood 2005;106:787-794.
    • (2005) Blood , vol.106 , pp. 787-794
    • Sledz, C.A.1    Williams, B.R.2
  • 6
    • 83255185737 scopus 로고    scopus 로고
    • Special delivery: targeted therapy with small RNAs
    • Peer D, Lieberman J. Special delivery: targeted therapy with small RNAs. Gene Ther 2011;18:1127-1133.
    • (2011) Gene Ther , vol.18 , pp. 1127-1133
    • Peer, D.1    Lieberman, J.2
  • 7
    • 23844474160 scopus 로고    scopus 로고
    • Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
    • Song E, et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat Biotechnol 2005;23:709-717.
    • (2005) Nat Biotechnol , vol.23 , pp. 709-717
    • Song, E.1
  • 8
    • 38849166053 scopus 로고    scopus 로고
    • Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target
    • Peer D, Park EJ, Morishita Y, Carman CV, Shimaoka M. Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target. Science 2008;319:627-630.
    • (2008) Science , vol.319 , pp. 627-630
    • Peer, D.1    Park, E.J.2    Morishita, Y.3    Carman, C.V.4    Shimaoka, M.5
  • 9
    • 30144434185 scopus 로고    scopus 로고
    • An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection
    • Palliser D, et al. An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection. Nature 2006;439:89-94.
    • (2006) Nature , vol.439 , pp. 89-94
    • Palliser, D.1
  • 10
    • 0037348329 scopus 로고    scopus 로고
    • RNA interference targeting Fas protects mice from fulminant hepatitis
    • Song E, et al. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med 2003;9:347-351.
    • (2003) Nat Med , vol.9 , pp. 347-351
    • Song, E.1
  • 11
    • 54949095836 scopus 로고    scopus 로고
    • Misinterpreting the therapeutic effects of small interfering RNA caused by immune stimulation
    • Robbins M, et al. Misinterpreting the therapeutic effects of small interfering RNA caused by immune stimulation. Hum Gene Ther 2008;19:991-999.
    • (2008) Hum Gene Ther , vol.19 , pp. 991-999
    • Robbins, M.1
  • 12
    • 41649115210 scopus 로고    scopus 로고
    • Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
    • Kleinman ME, et al. Sequence- and target-independent angiogenesis suppression by siRNA via TLR3. Nature 2008;452:591-597.
    • (2008) Nature , vol.452 , pp. 591-597
    • Kleinman, M.E.1
  • 13
    • 84865052732 scopus 로고    scopus 로고
    • RNA inhibition highlights cyclin d1 as a potential therapeutic target for mantle cell lymphoma
    • Weinstein S, et al. RNA inhibition highlights cyclin d1 as a potential therapeutic target for mantle cell lymphoma. PLoS ONE 2012;7:e43343.
    • (2012) PLoS ONE , vol.7
    • Weinstein, S.1
  • 14
    • 84867642276 scopus 로고    scopus 로고
    • RNAi-based nanomedicines for targeted personalized therapy
    • Daka A, Peer D. RNAi-based nanomedicines for targeted personalized therapy. Adv Drug Deliv Rev 2012;64:1508-1521.
    • (2012) Adv Drug Deliv Rev , vol.64 , pp. 1508-1521
    • Daka, A.1    Peer, D.2
  • 15
    • 33646185371 scopus 로고    scopus 로고
    • RNAi-mediated gene silencing in non-human primates
    • Zimmermann TS, et al. RNAi-mediated gene silencing in non-human primates. Nature 2006;441:111-114.
    • (2006) Nature , vol.441 , pp. 111-114
    • Zimmermann, T.S.1
  • 16
    • 10344261343 scopus 로고    scopus 로고
    • siRNA relieves chronic neuropathic pain
    • Dorn G, et al. siRNA relieves chronic neuropathic pain. Nucleic Acids Res 2004;32:e49.
    • (2004) Nucleic Acids Res , vol.32
    • Dorn, G.1
  • 17
    • 31444440290 scopus 로고    scopus 로고
    • Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1
    • Shen J, et al. Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1. Gene Ther 2006;13:225-234.
    • (2006) Gene Ther , vol.13 , pp. 225-234
    • Shen, J.1
  • 18
    • 0042173218 scopus 로고    scopus 로고
    • SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth
    • Filleur S, et al. SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth. Cancer Res 2003;63:3919-3922.
    • (2003) Cancer Res , vol.63 , pp. 3919-3922
    • Filleur, S.1
  • 19
    • 0037195903 scopus 로고    scopus 로고
    • RNA interference reveals a requirement for myocyte enhancer factor 2A in activity-dependent neuronal survival
    • Gaudilliere B, Shi Y, Bonni A. RNA interference reveals a requirement for myocyte enhancer factor 2A in activity-dependent neuronal survival. J Biol Chem 2002;277:46442-46446.
    • (2002) J Biol Chem , vol.277 , pp. 46442-46446
    • Gaudilliere, B.1    Shi, Y.2    Bonni, A.3
  • 20
    • 0038132996 scopus 로고    scopus 로고
    • Allele-specific silencing of dominant disease genes
    • Miller VM, et al. Allele-specific silencing of dominant disease genes. Proc Natl Acad Sci USA 2003;100:7195-7200.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 7195-7200
    • Miller, V.M.1
  • 21
    • 27744533560 scopus 로고    scopus 로고
    • Silencing primary dystonia: lentiviral-mediated RNA interference therapy for DYT1 dystonia
    • Gonzalez-Alegre P, Bode N, Davidson BL, Paulson HL. Silencing primary dystonia: lentiviral-mediated RNA interference therapy for DYT1 dystonia. J Neurosci 2005;25:10502-10509.
    • (2005) J Neurosci , vol.25 , pp. 10502-10509
    • Gonzalez-Alegre, P.1    Bode, N.2    Davidson, B.L.3    Paulson, H.L.4
  • 22
    • 33751099034 scopus 로고    scopus 로고
    • RNAi therapeutics: a potential new class of pharmaceutical drugs
    • Bumcrot D, Manoharan M, Koteliansky V, Sah DW. RNAi therapeutics: a potential new class of pharmaceutical drugs. Nat Chem Biol 2006;2:711-719.
    • (2006) Nat Chem Biol , vol.2 , pp. 711-719
    • Bumcrot, D.1    Manoharan, M.2    Koteliansky, V.3    Sah, D.W.4
  • 23
    • 66349108231 scopus 로고    scopus 로고
    • A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
    • Bramsen JB, et al. A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity. Nucleic Acids Res 2009;37:2867-2881.
    • (2009) Nucleic Acids Res , vol.37 , pp. 2867-2881
    • Bramsen, J.B.1
  • 25
    • 57349134691 scopus 로고    scopus 로고
    • Chemical modification of siRNAs for in vivo use
    • Behlke MA. Chemical modification of siRNAs for in vivo use. Oligonucleotides 2008;18:305-319.
    • (2008) Oligonucleotides , vol.18 , pp. 305-319
    • Behlke, M.A.1
  • 26
    • 33645148088 scopus 로고    scopus 로고
    • The silent treatment: siRNAs as small molecule drugs
    • Dykxhoorn DM, Palliser D, Lieberman J. The silent treatment: siRNAs as small molecule drugs. Gene Ther 2006;13:541-552.
    • (2006) Gene Ther , vol.13 , pp. 541-552
    • Dykxhoorn, D.M.1    Palliser, D.2    Lieberman, J.3
  • 27
    • 33847036990 scopus 로고    scopus 로고
    • Strategies for silencing human disease using RNA interference
    • Kim DH, Rossi JJ. Strategies for silencing human disease using RNA interference. Nat Rev Genet 2007;8:173-184.
    • (2007) Nat Rev Genet , vol.8 , pp. 173-184
    • Kim, D.H.1    Rossi, J.J.2
  • 28
    • 33645500266 scopus 로고    scopus 로고
    • Progress towards in vivo use of siRNAs
    • Behlke MA. Progress towards in vivo use of siRNAs. Mol Ther 2006;13:644-670.
    • (2006) Mol Ther , vol.13 , pp. 644-670
    • Behlke, M.A.1
  • 29
    • 14544280255 scopus 로고    scopus 로고
    • The silent revolution: RNA interference as basic biology, research tool, and therapeutic
    • Dykxhoorn DM, Lieberman J. The silent revolution: RNA interference as basic biology, research tool, and therapeutic. Annu Rev Med 2005;56:401-423.
    • (2005) Annu Rev Med , vol.56 , pp. 401-423
    • Dykxhoorn, D.M.1    Lieberman, J.2
  • 30
    • 82455217434 scopus 로고    scopus 로고
    • Grand challenges in modulating the immune response with RNAi nanomedicines
    • Goldsmith M, Mizrahy S, Peer D. Grand challenges in modulating the immune response with RNAi nanomedicines. Nanomedicine 2011;6:1771-1785.
    • (2011) Nanomedicine , vol.6 , pp. 1771-1785
    • Goldsmith, M.1    Mizrahy, S.2    Peer, D.3
  • 31
    • 33645823860 scopus 로고    scopus 로고
    • Efficient nonviral gene delivery into primary lymphocytes from rats and mice
    • Goffinet C, Keppler OT. Efficient nonviral gene delivery into primary lymphocytes from rats and mice. FASEB J 2006;20:500-502.
    • (2006) FASEB J , vol.20 , pp. 500-502
    • Goffinet, C.1    Keppler, O.T.2
  • 32
    • 70350142394 scopus 로고    scopus 로고
    • An immobilized nanoparticle-based platform for efficient gene knockdown of targeted cells in the circulation
    • Huang Z, King MR. An immobilized nanoparticle-based platform for efficient gene knockdown of targeted cells in the circulation. Gene Ther 2009;16:1271-1282.
    • (2009) Gene Ther , vol.16 , pp. 1271-1282
    • Huang, Z.1    King, M.R.2
  • 33
    • 67149093390 scopus 로고    scopus 로고
    • Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein
    • Eguchi A, et al. Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein. Nat Biotechnol 2009;27:567-571.
    • (2009) Nat Biotechnol , vol.27 , pp. 567-571
    • Eguchi, A.1
  • 34
    • 48349105059 scopus 로고    scopus 로고
    • Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy
    • Zhou J, Li H, Li S, Zaia J, Rossi JJ. Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy. Mol Ther 2008;16:1481-1489.
    • (2008) Mol Ther , vol.16 , pp. 1481-1489
    • Zhou, J.1    Li, H.2    Li, S.3    Zaia, J.4    Rossi, J.J.5
  • 35
    • 66249129385 scopus 로고    scopus 로고
    • Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells
    • Zhou J, et al. Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells. Nucleic Acids Res 2009;37:3094-3109.
    • (2009) Nucleic Acids Res , vol.37 , pp. 3094-3109
    • Zhou, J.1
  • 36
    • 70349971417 scopus 로고    scopus 로고
    • In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses
    • Kortylewski M, et al. In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses. Nat Biotechnol 2009;27:925-932.
    • (2009) Nat Biotechnol , vol.27 , pp. 925-932
    • Kortylewski, M.1
  • 37
    • 38649095979 scopus 로고    scopus 로고
    • Downregulation of monocyte chemoattractant protein-1 involving short interfering RNA attenuates hapten-induced contact hypersensitivity
    • Ishimoto T, et al. Downregulation of monocyte chemoattractant protein-1 involving short interfering RNA attenuates hapten-induced contact hypersensitivity. Mol Ther 2008;16:387-395.
    • (2008) Mol Ther , vol.16 , pp. 387-395
    • Ishimoto, T.1
  • 38
    • 49549117077 scopus 로고    scopus 로고
    • T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice
    • Kumar P, et al. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell 2008;134:577-586.
    • (2008) Cell , vol.134 , pp. 577-586
    • Kumar, P.1
  • 39
    • 77649207166 scopus 로고    scopus 로고
    • Targeted delivery of small interfering RNA to human dendritic cells to suppress dengue virus infection and associated proinflammatory cytokine production
    • Subramanya S, et al. Targeted delivery of small interfering RNA to human dendritic cells to suppress dengue virus infection and associated proinflammatory cytokine production. J Virol 2010;84:2490-2501.
    • (2010) J Virol , vol.84 , pp. 2490-2501
    • Subramanya, S.1
  • 40
    • 77952011113 scopus 로고    scopus 로고
    • Targeted delivery of siRNA to macrophages for anti-inflammatory treatment
    • Kim SS, et al. Targeted delivery of siRNA to macrophages for anti-inflammatory treatment. Mol Ther 2010;18:993-1001.
    • (2010) Mol Ther , vol.18 , pp. 993-1001
    • Kim, S.S.1
  • 41
    • 34447114618 scopus 로고    scopus 로고
    • Transvascular delivery of small interfering RNA to the central nervous system
    • Kumar P, et al. Transvascular delivery of small interfering RNA to the central nervous system. Nature 2007;448:39-43.
    • (2007) Nature , vol.448 , pp. 39-43
    • Kumar, P.1
  • 42
    • 34247255870 scopus 로고    scopus 로고
    • Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1
    • Peer D, Zhu P, Carman CV, Lieberman J, Shimaoka M. Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1. Proc Natl Acad Sci USA 2007;104:4095-4100.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 4095-4100
    • Peer, D.1    Zhu, P.2    Carman, C.V.3    Lieberman, J.4    Shimaoka, M.5
  • 43
    • 0025182959 scopus 로고
    • Adhesion receptors of the immune system
    • Springer TA. Adhesion receptors of the immune system. Nature 1990;346:425-434.
    • (1990) Nature , vol.346 , pp. 425-434
    • Springer, T.A.1
  • 44
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: bidirectional, allosteric signaling machines
    • Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell 2002;110:673-687.
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 45
    • 0345107256 scopus 로고    scopus 로고
    • A novel targeted T-cell modulator, efalizumab, for plaque psoriasis
    • Lebwohl M, et al. A novel targeted T-cell modulator, efalizumab, for plaque psoriasis. N Engl J Med 2003;349:2004-2013.
    • (2003) N Engl J Med , vol.349 , pp. 2004-2013
    • Lebwohl, M.1
  • 46
    • 27644441529 scopus 로고    scopus 로고
    • Natalizumab induction and maintenance therapy for Crohn's disease
    • Sandborn WJ, et al. Natalizumab induction and maintenance therapy for Crohn's disease. N Engl J Med 2005;353:1912-1925.
    • (2005) N Engl J Med , vol.353 , pp. 1912-1925
    • Sandborn, W.J.1
  • 47
    • 0142026204 scopus 로고    scopus 로고
    • Therapeutic antagonists and conformational regulation of integrin function
    • Shimaoka M, Springer TA. Therapeutic antagonists and conformational regulation of integrin function. Nat Rev Drug Discov 2003;2:703-716.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 703-716
    • Shimaoka, M.1    Springer, T.A.2
  • 48
    • 0037428080 scopus 로고    scopus 로고
    • Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation
    • Shimaoka M, et al. Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation. Cell 2003;112:99-111.
    • (2003) Cell , vol.112 , pp. 99-111
    • Shimaoka, M.1
  • 49
    • 78649529391 scopus 로고    scopus 로고
    • Induction of therapeutic gene silencing in leukocyte-implicated diseases by targeted and stabilized nanoparticles: a mini-review
    • Peer D. Induction of therapeutic gene silencing in leukocyte-implicated diseases by targeted and stabilized nanoparticles: a mini-review. J Control Rel 2010;148:63-68.
    • (2010) J Control Rel , vol.148 , pp. 63-68
    • Peer, D.1
  • 50
    • 28644449881 scopus 로고    scopus 로고
    • Dynamic partitioning into lipid rafts controls the endo-exocytic cycle of the alphaL/beta2 integrin, LFA-1, during leukocyte chemotaxis
    • Fabbri M, et al. Dynamic partitioning into lipid rafts controls the endo-exocytic cycle of the alphaL/beta2 integrin, LFA-1, during leukocyte chemotaxis. Mol Biol Cell 2005;16:5793-5803.
    • (2005) Mol Biol Cell , vol.16 , pp. 5793-5803
    • Fabbri, M.1
  • 51
    • 4243159775 scopus 로고    scopus 로고
    • In vitro internalization, intracellular transport, and clearance of an anti-CD11a antibody (Raptiva) by human T-cells
    • Coffey GP, et al. In vitro internalization, intracellular transport, and clearance of an anti-CD11a antibody (Raptiva) by human T-cells. J Pharmacol Exp Ther 2004;310:896-904.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 896-904
    • Coffey, G.P.1
  • 52
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm
    • Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994;76:301-314.
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 53
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher EC, Picker LJ. Lymphocyte homing and homeostasis. Science 1996;272:60-66.
    • (1996) Science , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, L.J.2
  • 55
    • 33748996774 scopus 로고    scopus 로고
    • AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes
    • Shimaoka M, et al. AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes. Proc Natl Acad Sci USA 2006;103:13991-13996.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13991-13996
    • Shimaoka, M.1
  • 56
    • 80054725664 scopus 로고    scopus 로고
    • Integrin-targeted nanoparticles for siRNA delivery
    • Ben-Arie N, Kedmi R, Peer D. Integrin-targeted nanoparticles for siRNA delivery. Methods Mol Biol 2012;757:497-507.
    • (2012) Methods Mol Biol , vol.757 , pp. 497-507
    • Ben-Arie, N.1    Kedmi, R.2    Peer, D.3
  • 57
    • 76349095131 scopus 로고    scopus 로고
    • RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice
    • Kim SS, et al. RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice. Mol Ther 2010;18:370-376.
    • (2010) Mol Ther , vol.18 , pp. 370-376
    • Kim, S.S.1
  • 58
    • 77954385672 scopus 로고    scopus 로고
    • The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation
    • Kedmi R, Ben-Arie N, Peer D. The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation. Biomaterials 2010;31:6867-6875.
    • (2010) Biomaterials , vol.31 , pp. 6867-6875
    • Kedmi, R.1    Ben-Arie, N.2    Peer, D.3
  • 59
    • 84869200994 scopus 로고    scopus 로고
    • Immunotoxicity derived from manipulating leukocytes with lipid-based nanoparticles
    • Peer D. Immunotoxicity derived from manipulating leukocytes with lipid-based nanoparticles. Adv Drug Deliv Rev 2012;64:1738-1748.
    • (2012) Adv Drug Deliv Rev , vol.64 , pp. 1738-1748
    • Peer, D.1
  • 60
    • 84862691394 scopus 로고    scopus 로고
    • Altering the immune response with lipid-based nanoparticles
    • Landesman-Milo D, Peer D. Altering the immune response with lipid-based nanoparticles. J Control Rel 2012;161:600-608.
    • (2012) J Control Rel , vol.161 , pp. 600-608
    • Landesman-Milo, D.1    Peer, D.2
  • 61
    • 0038025858 scopus 로고    scopus 로고
    • Hyaluronan is a key component in cryoprotection and formulation of targeted unilamellar liposomes
    • Peer D, Florentin A, Margalit R. Hyaluronan is a key component in cryoprotection and formulation of targeted unilamellar liposomes. Biochim Biophys Acta 2003;1612:76-82.
    • (2003) Biochim Biophys Acta , vol.1612 , pp. 76-82
    • Peer, D.1    Florentin, A.2    Margalit, R.3
  • 62
    • 0347285397 scopus 로고    scopus 로고
    • Loading mitomycin C inside long circulating hyaluronan targeted nano-liposomes increases its antitumor activity in three mice tumor models
    • Peer D, Margalit R. Loading mitomycin C inside long circulating hyaluronan targeted nano-liposomes increases its antitumor activity in three mice tumor models. Int J Cancer 2004;108:780-789.
    • (2004) Int J Cancer , vol.108 , pp. 780-789
    • Peer, D.1    Margalit, R.2
  • 63
    • 3142783426 scopus 로고    scopus 로고
    • Tumor-targeted hyaluronan nanoliposomes increase the antitumor activity of liposomal Doxorubicin in syngeneic and human xenograft mouse tumor models
    • Peer D, Margalit R. Tumor-targeted hyaluronan nanoliposomes increase the antitumor activity of liposomal Doxorubicin in syngeneic and human xenograft mouse tumor models. Neoplasia 2004;6:343-353.
    • (2004) Neoplasia , vol.6 , pp. 343-353
    • Peer, D.1    Margalit, R.2
  • 64
    • 84858680500 scopus 로고    scopus 로고
    • Polysaccharides as building blocks for nanotherapeutics
    • Mizrahy S, Peer D. Polysaccharides as building blocks for nanotherapeutics. Chem Soc Rev 2012;41:2623-2640.
    • (2012) Chem Soc Rev , vol.41 , pp. 2623-2640
    • Mizrahy, S.1    Peer, D.2
  • 65
    • 81255127530 scopus 로고    scopus 로고
    • Hyaluronan-coated nanoparticles: the influence of the molecular weight on CD44-hyaluronan interactions and on the immune response
    • Mizrahy S, et al. Hyaluronan-coated nanoparticles: the influence of the molecular weight on CD44-hyaluronan interactions and on the immune response. J Control Rel 2011;156:231-238.
    • (2011) J Control Rel , vol.156 , pp. 231-238
    • Mizrahy, S.1
  • 66
    • 0037376168 scopus 로고    scopus 로고
    • Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells
    • Stacey DW. Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells. Curr Opin Cell Biol 2003;15:158-163.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 158-163
    • Stacey, D.W.1
  • 67
    • 33749657631 scopus 로고    scopus 로고
    • Targeting cyclins and cyclin-dependent kinases in cancer: lessons from mice, hopes for therapeutic applications in human
    • Lee YM, Sicinski P. Targeting cyclins and cyclin-dependent kinases in cancer: lessons from mice, hopes for therapeutic applications in human. Cell Cycle 2006;5:2110-2114.
    • (2006) Cell Cycle , vol.5 , pp. 2110-2114
    • Lee, Y.M.1    Sicinski, P.2
  • 68
    • 33645118564 scopus 로고    scopus 로고
    • Cyclin D1: polymorphism, aberrant splicing and cancer risk
    • Knudsen KE, Diehl JA, Haiman CA, Knudsen ES. Cyclin D1: polymorphism, aberrant splicing and cancer risk. Oncogene 2006;25:1620-1628.
    • (2006) Oncogene , vol.25 , pp. 1620-1628
    • Knudsen, K.E.1    Diehl, J.A.2    Haiman, C.A.3    Knudsen, E.S.4
  • 69
    • 9444236895 scopus 로고    scopus 로고
    • Minireview: Cyclin D1: normal and abnormal functions
    • Fu M, Wang C, Li Z, Sakamaki T, Pestell RG. Minireview: Cyclin D1: normal and abnormal functions. Endocrinology 2004;145:5439-5447.
    • (2004) Endocrinology , vol.145 , pp. 5439-5447
    • Fu, M.1    Wang, C.2    Li, Z.3    Sakamaki, T.4    Pestell, R.G.5
  • 70
    • 34147096292 scopus 로고    scopus 로고
    • Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression
    • Tashiro E, Tsuchiya A, Imoto M. Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression. Cancer Sci 2007;98:629-635.
    • (2007) Cancer Sci , vol.98 , pp. 629-635
    • Tashiro, E.1    Tsuchiya, A.2    Imoto, M.3
  • 71
    • 25444440873 scopus 로고    scopus 로고
    • Cell cycle progression without cyclin D-CDK4 and cyclin D-CDK6 complexes
    • Kozar K, Sicinski P. Cell cycle progression without cyclin D-CDK4 and cyclin D-CDK6 complexes. Cell Cycle 2005;4:388-391.
    • (2005) Cell Cycle , vol.4 , pp. 388-391
    • Kozar, K.1    Sicinski, P.2
  • 72
    • 20844444135 scopus 로고    scopus 로고
    • Targeting Stat3 in cancer therapy
    • Jing N, Tweardy DJ. Targeting Stat3 in cancer therapy. Anticancer Drugs 2005;16:601-607.
    • (2005) Anticancer Drugs , vol.16 , pp. 601-607
    • Jing, N.1    Tweardy, D.J.2
  • 73
    • 23044508946 scopus 로고    scopus 로고
    • Cyclin D1 in breast cancer pathogenesis
    • Arnold A, Papanikolaou A. Cyclin D1 in breast cancer pathogenesis. J Clin Oncol 2005;23:4215-4224.
    • (2005) J Clin Oncol , vol.23 , pp. 4215-4224
    • Arnold, A.1    Papanikolaou, A.2
  • 74
    • 34648824397 scopus 로고    scopus 로고
    • Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics
    • Jares P, Colomer D, Campo E. Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics. Nat Rev Cancer 2007;7:750-762.
    • (2007) Nat Rev Cancer , vol.7 , pp. 750-762
    • Jares, P.1    Colomer, D.2    Campo, E.3
  • 75
    • 0027938209 scopus 로고
    • Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age
    • Hunter T, Pines J. Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. Cell 1994;79:573-582.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 76
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ. Cancer cell cycles. Science 1996;274:1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 77
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • Sherr CJ, McCormick F. The RB and p53 pathways in cancer. Cancer Cell 2002;2:103-112.
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 78
    • 27244434794 scopus 로고    scopus 로고
    • Pathogenesis of mantle-cell lymphoma: all oncogenic roads lead to dysregulation of cell cycle and DNA damage response pathways
    • Fernandez V, Hartmann E, Ott G, Campo E, Rosenwald A. Pathogenesis of mantle-cell lymphoma: all oncogenic roads lead to dysregulation of cell cycle and DNA damage response pathways. J Clin Oncol 2005;23:6364-6369.
    • (2005) J Clin Oncol , vol.23 , pp. 6364-6369
    • Fernandez, V.1    Hartmann, E.2    Ott, G.3    Campo, E.4    Rosenwald, A.5
  • 80
    • 38849099131 scopus 로고    scopus 로고
    • Molecular biology. The art of assembly
    • Szoka F. Molecular biology. The art of assembly. Science 2008;319:578-579.
    • (2008) Science , vol.319 , pp. 578-579
    • Szoka, F.1
  • 81
    • 41849089395 scopus 로고    scopus 로고
    • siRNAs with guts
    • Maclachlan I. siRNAs with guts. Nat Biotechnol 2008;26:403-405.
    • (2008) Nat Biotechnol , vol.26 , pp. 403-405
    • Maclachlan, I.1
  • 82
    • 79955761548 scopus 로고    scopus 로고
    • Hyaluronan-grafted particle clusters loaded with Mitomycin C as selective nanovectors for primary head and neck cancers
    • Bachar G, et al. Hyaluronan-grafted particle clusters loaded with Mitomycin C as selective nanovectors for primary head and neck cancers. Biomaterials 2011;32:4840-4848.
    • (2011) Biomaterials , vol.32 , pp. 4840-4848
    • Bachar, G.1
  • 83
    • 84878263116 scopus 로고    scopus 로고
    • Hyaluronan grafted lipid-based nanoparticles as RNAi carriers for cancer cells
    • doi: 10.1016/j.canlet.2012.08.024.
    • Landesman-Milo D, et al. Hyaluronan grafted lipid-based nanoparticles as RNAi carriers for cancer cells. Cancer Lett 2012. doi: 10.1016/j.canlet.2012.08.024.
    • (2012) Cancer Lett
    • Landesman-Milo, D.1
  • 84
    • 11144282529 scopus 로고    scopus 로고
    • Antisense and siRNA as agonists of Toll-like receptors
    • Agrawal S, Kandimalla ER. Antisense and siRNA as agonists of Toll-like receptors. Nat Biotechnol 2004;22:1533-1537.
    • (2004) Nat Biotechnol , vol.22 , pp. 1533-1537
    • Agrawal, S.1    Kandimalla, E.R.2
  • 85
    • 2442705429 scopus 로고    scopus 로고
    • Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3
    • Kariko K, Bhuyan P, Capodici J, Weissman D. Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3. J Immunol 2004;172:6545-6549.
    • (2004) J Immunol , vol.172 , pp. 6545-6549
    • Kariko, K.1    Bhuyan, P.2    Capodici, J.3    Weissman, D.4
  • 87
    • 22344454846 scopus 로고    scopus 로고
    • Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
    • Judge AD, Sood V, Shaw JR, Fang D, McClintock K, MacLachlan I. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol 2005;23:457-462.
    • (2005) Nat Biotechnol , vol.23 , pp. 457-462
    • Judge, A.D.1    Sood, V.2    Shaw, J.R.3    Fang, D.4    McClintock, K.5    MacLachlan, I.6
  • 88
    • 20144389695 scopus 로고    scopus 로고
    • Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7
    • Hornung V, et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med 2005;11:263-270.
    • (2005) Nat Med , vol.11 , pp. 263-270
    • Hornung, V.1
  • 89
    • 44649137559 scopus 로고    scopus 로고
    • Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses
    • Forsbach A, et al. Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses. J Immunol 2008;180:3729-3738.
    • (2008) J Immunol , vol.180 , pp. 3729-3738
    • Forsbach, A.1
  • 90
    • 18044365415 scopus 로고    scopus 로고
    • Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization
    • Sioud M. Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization. J Mol Biol 2005;348:1079-1090.
    • (2005) J Mol Biol , vol.348 , pp. 1079-1090
    • Sioud, M.1
  • 91
    • 33748069824 scopus 로고    scopus 로고
    • siRNA and isRNA: two edges of one sword
    • Schlee M, Hornung V, Hartmann G. siRNA and isRNA: two edges of one sword. Mol Ther 2006;14:463-470.
    • (2006) Mol Ther , vol.14 , pp. 463-470
    • Schlee, M.1    Hornung, V.2    Hartmann, G.3
  • 93
    • 33750201146 scopus 로고    scopus 로고
    • Controlling activation of the RNA-dependent protein kinase by siRNAs using site-specific chemical modification
    • Puthenveetil S, Whitby L, Ren J, Kelnar K, Krebs JF, Beal PA. Controlling activation of the RNA-dependent protein kinase by siRNAs using site-specific chemical modification. Nucl Acids Res 2006;34:4900-4911.
    • (2006) Nucl Acids Res , vol.34 , pp. 4900-4911
    • Puthenveetil, S.1    Whitby, L.2    Ren, J.3    Kelnar, K.4    Krebs, J.F.5    Beal, P.A.6
  • 94
    • 32944454941 scopus 로고    scopus 로고
    • Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo
    • Judge AD, Bola G, Lee AC, MacLachlan I. Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo. Mol Ther 2006;13:494-505.
    • (2006) Mol Ther , vol.13 , pp. 494-505
    • Judge, A.D.1    Bola, G.2    Lee, A.C.3    MacLachlan, I.4
  • 95
    • 23444445660 scopus 로고    scopus 로고
    • Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
    • Morrissey DV, et al. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs. Nat Biotechnol 2005;23:1002-1007.
    • (2005) Nat Biotechnol , vol.23 , pp. 1002-1007
    • Morrissey, D.V.1
  • 96
    • 71949092463 scopus 로고    scopus 로고
    • Nanomedicine based approaches for the delivery of siRNA in cancer
    • Ozpolat B, Sood AK, Lopez-Berestein G. Nanomedicine based approaches for the delivery of siRNA in cancer. J Intern Med 2010;267:44-53.
    • (2010) J Intern Med , vol.267 , pp. 44-53
    • Ozpolat, B.1    Sood, A.K.2    Lopez-Berestein, G.3
  • 98
    • 84859269808 scopus 로고    scopus 로고
    • Liposome based systems for systemic siRNA delivery: Stability in blood sets the requirements for optimal carrier design
    • Buyens K, et al. Liposome based systems for systemic siRNA delivery: Stability in blood sets the requirements for optimal carrier design. J Control Rel 2012;158:362-370.
    • (2012) J Control Rel , vol.158 , pp. 362-370
    • Buyens, K.1
  • 99
    • 79959949296 scopus 로고    scopus 로고
    • Synthesis and characterization of degradable multivalent cationic lipids with disulfide-bond spacers for gene delivery
    • Shirazi RS, Ewert KK, Leal C, Majzoub RN, Bouxsein NF, Safinya CR. Synthesis and characterization of degradable multivalent cationic lipids with disulfide-bond spacers for gene delivery. Biochim Biophys Acta 2011;1808:2156-2166.
    • (2011) Biochim Biophys Acta , vol.1808 , pp. 2156-2166
    • Shirazi, R.S.1    Ewert, K.K.2    Leal, C.3    Majzoub, R.N.4    Bouxsein, N.F.5    Safinya, C.R.6
  • 100
    • 43049176170 scopus 로고    scopus 로고
    • A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
    • Akinc A, et al. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat Biotechnol 2008;26:561-569.
    • (2008) Nat Biotechnol , vol.26 , pp. 561-569
    • Akinc, A.1
  • 101
    • 0031587422 scopus 로고    scopus 로고
    • Positively charged liposome functions as an efficient immunoadjuvant in inducing immune responses to soluble proteins
    • Nakanishi T, et al. Positively charged liposome functions as an efficient immunoadjuvant in inducing immune responses to soluble proteins. Biochem Biophys Res Commun 1997;240:793-797.
    • (1997) Biochem Biophys Res Commun , vol.240 , pp. 793-797
    • Nakanishi, T.1
  • 103
    • 77954599597 scopus 로고    scopus 로고
    • Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer
    • Chen Y, Bathula SR, Li J, Huang L. Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer. J Biol Chem 2010;285:22639-22650.
    • (2010) J Biol Chem , vol.285 , pp. 22639-22650
    • Chen, Y.1    Bathula, S.R.2    Li, J.3    Huang, L.4
  • 104
    • 6344291687 scopus 로고    scopus 로고
    • Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA
    • Spagnou S, Miller AD, Keller M. Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA. Biochemistry 2004;43:13348-13356.
    • (2004) Biochemistry , vol.43 , pp. 13348-13356
    • Spagnou, S.1    Miller, A.D.2    Keller, M.3
  • 105
    • 81855212446 scopus 로고    scopus 로고
    • Assessing cellular toxicities in fibroblasts upon exposure to lipid-based nanoparticles: a high content analysis approach
    • Solmesky LJ, Shuman M, Goldsmith M, Weil M, Peer D. Assessing cellular toxicities in fibroblasts upon exposure to lipid-based nanoparticles: a high content analysis approach. Nanotechnology 2011;22:494016.
    • (2011) Nanotechnology , vol.22 , pp. 494016
    • Solmesky, L.J.1    Shuman, M.2    Goldsmith, M.3    Weil, M.4    Peer, D.5
  • 106
    • 44949169402 scopus 로고    scopus 로고
    • Cationic liposomal lipids: from gene carriers to cell signaling
    • Lonez C, Vandenbranden M, Ruysschaert JM. Cationic liposomal lipids: from gene carriers to cell signaling. Prog Lipid Res 2008;47:340-347.
    • (2008) Prog Lipid Res , vol.47 , pp. 340-347
    • Lonez, C.1    Vandenbranden, M.2    Ruysschaert, J.M.3
  • 108
    • 0025731906 scopus 로고
    • Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo
    • Allen TM, Hansen C, Martin F, Redemann C, Yau-Young A. Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo. Biochim Biophys Acta 1991;1066:29-36.
    • (1991) Biochim Biophys Acta , vol.1066 , pp. 29-36
    • Allen, T.M.1    Hansen, C.2    Martin, F.3    Redemann, C.4    Yau-Young, A.5
  • 109
    • 0025341615 scopus 로고
    • Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes
    • Klibanov AL, Maruyama K, Torchilin VP, Huang L. Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. FEBS Lett 1990;268:235-237.
    • (1990) FEBS Lett , vol.268 , pp. 235-237
    • Klibanov, A.L.1    Maruyama, K.2    Torchilin, V.P.3    Huang, L.4
  • 110
    • 0037436030 scopus 로고    scopus 로고
    • Accelerated clearance of PEGylated liposomes in rats after repeated injections
    • Ishida T, Maeda R, Ichihara M, Irimura K, Kiwada H. Accelerated clearance of PEGylated liposomes in rats after repeated injections. J Control Rel 2003;88:35-42.
    • (2003) J Control Rel , vol.88 , pp. 35-42
    • Ishida, T.1    Maeda, R.2    Ichihara, M.3    Irimura, K.4    Kiwada, H.5
  • 112
    • 34548653879 scopus 로고    scopus 로고
    • PEGylated liposomes elicit an anti-PEG IgM response in a T cell-independent manner
    • Ishida T, Wang X, Shimizu T, Nawata K, Kiwada H. PEGylated liposomes elicit an anti-PEG IgM response in a T cell-independent manner. J Control Rel 2007;122:349-355.
    • (2007) J Control Rel , vol.122 , pp. 349-355
    • Ishida, T.1    Wang, X.2    Shimizu, T.3    Nawata, K.4    Kiwada, H.5
  • 113
    • 84934442719 scopus 로고    scopus 로고
    • Alendronate liposomes for antitumor therapy: activation of gammadelta T Cells and inhibition of tumor growth
    • Gutman D, Epstein-Barash H, Tsuriel M, Golomb G. Alendronate liposomes for antitumor therapy: activation of gammadelta T Cells and inhibition of tumor growth. Adv Exp Med Biol 2012;733:165-179.
    • (2012) Adv Exp Med Biol , vol.733 , pp. 165-179
    • Gutman, D.1    Epstein-Barash, H.2    Tsuriel, M.3    Golomb, G.4
  • 114
    • 0032530721 scopus 로고    scopus 로고
    • Liposome-cell interactions in vitro: effect of liposome surface charge on the binding and endocytosis of conventional and sterically stabilized liposomes
    • Miller CR, Bondurant B, McLean SD, McGovern KA, O'Brien DF. Liposome-cell interactions in vitro: effect of liposome surface charge on the binding and endocytosis of conventional and sterically stabilized liposomes. Biochemistry 1998;37:12875-12883.
    • (1998) Biochemistry , vol.37 , pp. 12875-12883
    • Miller, C.R.1    Bondurant, B.2    McLean, S.D.3    McGovern, K.A.4    O'Brien, D.F.5
  • 115
    • 2342625401 scopus 로고    scopus 로고
    • Interaction of dendritic cells with antigen-containing liposomes: effect of bilayer composition
    • Foged C, Arigita C, Sundblad A, Jiskoot W, Storm G, Frokjaer S. Interaction of dendritic cells with antigen-containing liposomes: effect of bilayer composition. Vaccine 2004;22:1903-1913.
    • (2004) Vaccine , vol.22 , pp. 1903-1913
    • Foged, C.1    Arigita, C.2    Sundblad, A.3    Jiskoot, W.4    Storm, G.5    Frokjaer, S.6
  • 116
    • 38449095310 scopus 로고    scopus 로고
    • Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver
    • Gray MJ, et al. Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver. J Natl Cancer Inst 2008;100:109-120.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 109-120
    • Gray, M.J.1
  • 117
    • 33748364149 scopus 로고    scopus 로고
    • Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy
    • Halder J, et al. Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy. Clin Cancer Res 2006;12:4916-4924.
    • (2006) Clin Cancer Res , vol.12 , pp. 4916-4924
    • Halder, J.1
  • 118
    • 23044506285 scopus 로고    scopus 로고
    • Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery
    • Landen CN Jr, et al. Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery. Cancer Res 2005;65:6910-6918.
    • (2005) Cancer Res , vol.65 , pp. 6910-6918
    • Landen Jr., C.N.1
  • 119
    • 40949126550 scopus 로고    scopus 로고
    • Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth
    • Merritt WM, et al. Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth. J Natl Cancer Inst 2008;100:359-372.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 359-372
    • Merritt, W.M.1
  • 120
    • 36849084647 scopus 로고    scopus 로고
    • On future's doorstep: RNA interference and the pharmacopeia of tomorrow
    • Gewirtz AM. On future's doorstep: RNA interference and the pharmacopeia of tomorrow. J Clin Invest 2007;117:3612-3614.
    • (2007) J Clin Invest , vol.117 , pp. 3612-3614
    • Gewirtz, A.M.1
  • 121
    • 77951699994 scopus 로고    scopus 로고
    • Sustained small interfering RNA delivery by mesoporous silicon particles
    • Tanaka T, et al. Sustained small interfering RNA delivery by mesoporous silicon particles. Cancer Res 2010;70:3687-3696.
    • (2010) Cancer Res , vol.70 , pp. 3687-3696
    • Tanaka, T.1
  • 122
    • 55349098455 scopus 로고    scopus 로고
    • Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA
    • Villares GJ, et al. Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA. Cancer Res 2008;68:9078-9086.
    • (2008) Cancer Res , vol.68 , pp. 9078-9086
    • Villares, G.J.1
  • 123
    • 84857888962 scopus 로고    scopus 로고
    • Nanoparticle hydrophobicity dictates immune response
    • Moyano DF, et al. Nanoparticle hydrophobicity dictates immune response. J Am Chem Soc 2012;134:3965-3967.
    • (2012) J Am Chem Soc , vol.134 , pp. 3965-3967
    • Moyano, D.F.1
  • 124
    • 1842684991 scopus 로고    scopus 로고
    • Rolling adhesion through an extended conformation of integrin alphaLbeta2 and relation to alpha I and beta I-like domain interaction
    • Salas A, Shimaoka M, Kogan AN, Harwood C, von Andrian UH, Springer TA. Rolling adhesion through an extended conformation of integrin alphaLbeta2 and relation to alpha I and beta I-like domain interaction. Immunity 2004;20:393-406.
    • (2004) Immunity , vol.20 , pp. 393-406
    • Salas, A.1    Shimaoka, M.2    Kogan, A.N.3    Harwood, C.4    von Andrian, U.H.5    Springer, T.A.6


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