Glutathione and thioredoxin dependent systems in neurodegenerative disease: What can be learned from reverse genetics in mice

Neurochemistry International

Volumn 62, Issue 5, 2013, Pages 738-749

  Conrad, Marcus ^a   Schick, Joel ^a   Angeli, Jose Pedro Friedmann ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Glutathione; Knockout; Neurodegeneration; Oxidative stress; Thiols; Thioredoxin

Indexed keywords

ACYLTRANSFERASE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMINE OXIDASE (FLAVIN CONTAINING); ANTIINFECTIVE AGENT; APOPTOSIS SIGNAL REGULATING KINASE 1; CASPASE; CASPASE 3; CASPASE 8; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROXYL RADICAL; NITRIC OXIDE; PEROXIREDOXIN; PHOSPHATASE; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TAU PROTEIN; THIOREDOXIN; THIOREDOXIN REDUCTASE; XANTHINE OXIDASE;

BRAIN CELL; CELL FUNCTION; DEGENERATIVE DISEASE; DETOXIFICATION; ENZYME ACTIVITY; HUMAN; LIPID PEROXIDATION; MACROPHAGE; MITOCHONDRIAL MEMBRANE; NERVE DEGENERATION; NITROSYLATION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN LOCALIZATION; REVERSE GENETICS; REVIEW; SIGNAL TRANSDUCTION; SPERMATOGENESIS;

ANIMALS; BRAIN; CELL DEATH; GLUTATHIONE; MICE; NEURODEGENERATIVE DISEASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; THIOREDOXINS;

MUS;

EID: 84875708705     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2013.01.010     Document Type: Review

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