Short form glutathione peroxidase 4 is the essential isoform required for survival and somatic mitochondrial functions

Journal of Biological Chemistry

Volumn 284, Issue 45, 2009, Pages 30836-30844

  Liang, Hanyu ^a   Yoo, Si Eun ^b   Na, Ren ^a   Walter, Christi A ^a,b,c   Richardson, Arlan ^a,b,c   Ran, Qitao ^a,b,c  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT ENZYME; APOPTOSIS; DISTRIBUTION PATTERNS; GENES ENCODING; GLUTATHIONE PEROXIDASE; INDUCED APOPTOSIS; ISOFORMS; MALE FERTILITY; MITOCHONDRIAL FUNCTION; MULTIPLE FUNCTION; SIGNAL PEPTIDE; SOMATIC TISSUES; TRANSGENIC MICE; WILD TYPES;

AMINES; CELL DEATH; HISTOLOGY; MITOCHONDRIA; PLANTS (BOTANY); PROTEINS;

GENE ENCODING;

GLUTATHIONE PEROXIDASE; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO DEVELOPMENT; GENE FUNCTION; GENE LOCATION; GENE OVEREXPRESSION; KIDNEY; LIVER; MALE INFERTILITY; MITOCHONDRION; MOUSE; NONHUMAN; NULL ALLELE; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TARGETING; SPERMATOZOON; TESTIS; TISSUE DISTRIBUTION; TRANSGENIC MOUSE; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CELL SURVIVAL; FEMALE; GLUTATHIONE PEROXIDASE; HUMANS; ISOENZYMES; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PROTEIN TRANSPORT; SPERMATOZOA;

MUS; MUS MUSCULUS;

EID: 71449113005     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.032839     Document Type: Article

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