Glutathione S-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease

Journal of Biological Chemistry

Volumn 287, Issue 9, 2012, Pages 6628-6641

  Kim, Kiyoung ^a   Kim, Song Hee ^a   Kim, Jaekwang ^a,b   Kim, Heuijong ^a   Yim, Jeongbin ^a  

^a Seoul National University   (South Korea)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP SYNTHASE; DEFENSE MECHANISM; GLUTATHIONE-S-TRANSFERASE; GLUTATHIONYLATION; IN-VIVO; MITOCHONDRIAL DYSFUNCTION; MUTANT PHENOTYPE; NEURODEGENERATION; PARKINSON DISEASE; POTENTIAL THERAPIES;

GENES; RESTORATION;

DISEASES;

GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE OMEGA1; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; STRESS ACTIVATED PROTEIN KINASE; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOPAMINERGIC NERVE CELL; DOWN REGULATION; DROSOPHILA; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SUBUNIT; GENE; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MALE; MOLECULAR MECHANICS; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; PARKIN GENE; PARKINSON DISEASE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

ANIMALS; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GLUTATHIONE TRANSFERASE; HERBICIDES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MUTAGENESIS, SITE-DIRECTED; NERVE DEGENERATION; OXIDATIVE STRESS; PARAQUAT; PARKINSONIAN DISORDERS; PHENOTYPE; SIGNAL TRANSDUCTION; TUBULIN; UBIQUITIN-PROTEIN LIGASES; UNFOLDED PROTEIN RESPONSE;

EID: 84863137295     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.291179     Document Type: Article

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