Necrostatin-1 attenuates mitochondrial dysfunction in neurons and astrocytes following neonatal hypoxia-ischemia

Neuroscience

Volumn 219, Issue , 2012, Pages 192-203

  Chavez Valdez, R ^a,b   Martin, L J ^c   Flock, D L ^a   Northington, F J ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Astrocytes; Hypoxia ischemia; Mitochondria; Neurons; Receptor interacting protein 1 kinase; Regulated necrosis

Indexed keywords

3 NITROTYROSINE; ADENOSINE TRIPHOSPHATE; BETA ACTIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; NECROSTATIN 1; NITRIC OXIDE; PROTEIN BNIP3; PROTEIN KINASE INHIBITOR; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASTROCYTE; BRAIN HYPOXIA; BRAIN ISCHEMIA; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; FOREBRAIN; HYPOXIC ISCHEMIC ENCEPHALOPATHY; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRION; MOUSE; NERVE CELL; NEUROPROTECTION; NEWBORN; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEX DIFFERENCE; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; FEMALE; HYPOXIA-ISCHEMIA, BRAIN; IMIDAZOLES; IMMUNOBLOTTING; INDOLES; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; NEURONS; OXIDATION-REDUCTION; OXIDATIVE STRESS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTOME;

EID: 84864003121     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.05.002     Document Type: Article

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