메뉴 건너뛰기




Volumn 138, Issue 1, 2013, Pages 1-17

Epigenetic modifications by dietary phytochemicals: Implications for personalized nutrition

Author keywords

Carcinogenesis; DNA methylation; Epigenetics; Histone modification; Keywords; miRNA; Phytochemicals

Indexed keywords

ANTINEOPLASTIC AGENT; BMI1 PROTEIN; CURCUMIN; DIINDOLYLMETHANE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; E1A ASSOCIATED P300 PROTEIN; ELLAGITANNIN; GARLIC EXTRACT; GENISTEIN; HERBACEOUS AGENT; HISTONE ACETYLTRANSFERASE PCAF; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 5; LYCOPENE; PHENETHYL ISOTHIOCYNATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POLYCOMB GROUP PROTEIN; PROTEIN ARGININE METHYLTRANSFERASE; QUERCETIN; RESVERATROL; RIBOSEPHOSPHATE PYROPHOSPHOKINASE; SIRTUIN 1; SULFORAPHANE; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN;

EID: 84875217123     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2012.11.002     Document Type: Review
Times cited : (117)

References (184)
  • 1
    • 77951745289 scopus 로고    scopus 로고
    • Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF
    • S. Ali Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF Cancer Res 70 9 2010 3606 3617
    • (2010) Cancer Res , vol.70 , Issue.9 , pp. 3606-3617
    • Ali, S.1
  • 2
    • 33745541339 scopus 로고    scopus 로고
    • Antithrombotic and anticancer effects of garlic-derived sulfur compounds: A review
    • T. Ariga, and T. Seki Antithrombotic and anticancer effects of garlic-derived sulfur compounds: a review Biofactors 26 2 2006 93 103
    • (2006) Biofactors , vol.26 , Issue.2 , pp. 93-103
    • Ariga, T.1    Seki, T.2
  • 3
    • 77955490964 scopus 로고    scopus 로고
    • Symposium 2: Modern approaches to nutritional research challenges nutritional developmental epigenomics: Immediate and long-lasting effects in the Conference on 'Over- and undernutrition: Challenges and approaches
    • L. Attig Symposium 2: Modern approaches to nutritional research challenges nutritional developmental epigenomics: immediate and long-lasting effects in the Conference on 'Over- and undernutrition: challenges and approaches Proc Nutr Soc 69 2010 221 231
    • (2010) Proc Nutr Soc , vol.69 , pp. 221-231
    • Attig, L.1
  • 4
    • 33846703338 scopus 로고    scopus 로고
    • CHD5 is a tumor suppressor at human 1p36
    • A. Bagchi, and C. Papazoglu CHD5 is a tumor suppressor at human 1p36 Cell 128 3 2007 459 475
    • (2007) Cell , vol.128 , Issue.3 , pp. 459-475
    • Bagchi, A.1    Papazoglu, C.2
  • 5
    • 34248547564 scopus 로고    scopus 로고
    • Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma
    • A. Balakrishnan, and F.E. Bleeker Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma Cancer Res 67 8 2007 3545 3550
    • (2007) Cancer Res , vol.67 , Issue.8 , pp. 3545-3550
    • Balakrishnan, A.1    Bleeker, F.E.2
  • 6
    • 77950907191 scopus 로고    scopus 로고
    • The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3- gallate-dependent suppression of skin cancer cell survival
    • S. Balasubramanian The Bmi-1 polycomb protein antagonizes the (-)-epigallocatechin-3-gallate-dependent suppression of skin cancer cell survival Carcinogenesis 31 3 2010 496 503
    • (2010) Carcinogenesis , vol.31 , Issue.3 , pp. 496-503
    • Balasubramanian, S.1
  • 7
    • 80054782831 scopus 로고    scopus 로고
    • Sulforaphane suppresses polycomb group protein level via a proteasome-dependent mechanism in skin cancer cells
    • S. Balasubramanian, and Y.C. Chew Sulforaphane suppresses polycomb group protein level via a proteasome-dependent mechanism in skin cancer cells Mol Pharmacol 80 5 2011 870 878
    • (2011) Mol Pharmacol , vol.80 , Issue.5 , pp. 870-878
    • Balasubramanian, S.1    Chew, Y.C.2
  • 8
    • 10944243759 scopus 로고    scopus 로고
    • Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
    • K. Balasubramanyam Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription J Biol Chem 279 49 2004 51163 51171
    • (2004) J Biol Chem , vol.279 , Issue.49 , pp. 51163-51171
    • Balasubramanyam, K.1
  • 9
    • 79961211147 scopus 로고    scopus 로고
    • Attenuation of multi-targeted proliferation-linked signaling by 3,3'-diindolylmethane (DIM): From bench to clinic
    • S. Banerjee Attenuation of multi-targeted proliferation-linked signaling by 3,3'-diindolylmethane (DIM): from bench to clinic Mutat Res 728 1-2 2011 47 66
    • (2011) Mutat Res , vol.728 , Issue.12 , pp. 47-66
    • Banerjee, S.1
  • 10
    • 48749117943 scopus 로고    scopus 로고
    • Multi-targeted therapy of cancer by genistein
    • S. Banerjee, Y. Li, Z. Wang, and F.H. Sarkar Multi-targeted therapy of cancer by genistein Cancer Lett 269 2 2008 226 242
    • (2008) Cancer Lett , vol.269 , Issue.2 , pp. 226-242
    • Banerjee, S.1    Li, Y.2    Wang, Z.3    Sarkar, F.H.4
  • 11
    • 0028815434 scopus 로고
    • Effect of genistein on in vitro and in vivo models of cancer
    • S. Barnes Effect of genistein on in vitro and in vivo models of cancer J Nutr 125 Suppl. 3 1995 777S 783S
    • (1995) J Nutr , vol.125 , Issue.SUPPL. 3
    • Barnes, S.1
  • 12
    • 55749097776 scopus 로고    scopus 로고
    • Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
    • S. Basak, D. Pookot, E.J. Noonan, and R. Dahiya Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function Mol Cancer Ther 7 10 2008 3195 3202
    • (2008) Mol Cancer Ther , vol.7 , Issue.10 , pp. 3195-3202
    • Basak, S.1    Pookot, D.2    Noonan, E.J.3    Dahiya, R.4
  • 13
    • 38649100332 scopus 로고    scopus 로고
    • Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG
    • J.B. Berletch, C. Liu, W.K. Love, and L.G. Andrews Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG J Cell Biochem 103 2 2008 509 519
    • (2008) J Cell Biochem , vol.103 , Issue.2 , pp. 509-519
    • Berletch, J.B.1    Liu, C.2    Love, W.K.3    Andrews, L.G.4
  • 14
    • 67650078931 scopus 로고    scopus 로고
    • Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies
    • G. Bora-Tatar, D. Dayangaç-Erden, A.S. Demir, and S. Dalkara Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies Bioorg Med Chem Lett 17 14 2009 5219 5228
    • (2009) Bioorg Med Chem Lett , vol.17 , Issue.14 , pp. 5219-5228
    • Bora-Tatar, G.1    Dayangaç-Erden, D.2    Demir, A.S.3    Dalkara, S.4
  • 15
    • 79955513100 scopus 로고    scopus 로고
    • Aberrations of EZH2 in cancer
    • A. Chase, and N.C. Cross Aberrations of EZH2 in cancer Clin Cancer Res 17 9 2011 2613 2618
    • (2011) Clin Cancer Res , vol.17 , Issue.9 , pp. 2613-2618
    • Chase, A.1    Cross, N.C.2
  • 16
    • 79955024477 scopus 로고    scopus 로고
    • Epigallocatechin-3 gallate inhibits invasion, epithelial-mesenchymal transition, and tumor growth in oral cancer cells
    • P.N. Chen, S.C. Chu, W.H. Kuo, M.Y. Chou, J.K. Lin, and Y.S. Hsieh Epigallocatechin-3 gallate inhibits invasion, epithelial-mesenchymal transition, and tumor growth in oral cancer cells J Agric Food Chem 59 8 2011 3836 3844
    • (2011) J Agric Food Chem , vol.59 , Issue.8 , pp. 3836-3844
    • Chen, P.N.1    Chu, S.C.2    Kuo, W.H.3    Chou, M.Y.4    Lin, J.K.5    Hsieh, Y.S.6
  • 17
    • 36248957463 scopus 로고    scopus 로고
    • Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells
    • Y. Chen, W. Shu, W. Chen, and Q. Wu Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells Basic Clin Pharmacol Toxicol 101 6 2007 427 433
    • (2007) Basic Clin Pharmacol Toxicol , vol.101 , Issue.6 , pp. 427-433
    • Chen, Y.1    Shu, W.2    Chen, W.3    Wu, Q.4
  • 18
    • 78650774201 scopus 로고    scopus 로고
    • Resveratrol induces growth arrest and apoptosis through activation of FOXO transcription factors in prostate cancer cells
    • Q. Chen, S. Ganapathy, K.P. Singh, S. Shankar, and R.K. Srivastava Resveratrol induces growth arrest and apoptosis through activation of FOXO transcription factors in prostate cancer cells PLoS One 5 12 2010 e15288
    • (2010) PLoS One , vol.5 , Issue.12 , pp. 15288
    • Chen, Q.1    Ganapathy, S.2    Singh, K.P.3    Shankar, S.4    Srivastava, R.K.5
  • 19
    • 77449106593 scopus 로고    scopus 로고
    • Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention
    • K.L. Cheung, and A.N. Kong Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention AAPS J 12 1 2010 87 97
    • (2010) AAPS J , vol.12 , Issue.1 , pp. 87-97
    • Cheung, K.L.1    Kong, A.N.2
  • 20
    • 34047136564 scopus 로고    scopus 로고
    • Epigenomics: Novel aspect of genomic regulation
    • H.S. Cho, J.H. Park, and Y.J. Kim Epigenomics: novel aspect of genomic regulation Biochem Mol Biol 40 2 2007 151 155
    • (2007) Biochem Mol Biol , vol.40 , Issue.2 , pp. 151-155
    • Cho, H.S.1    Park, J.H.2    Kim, Y.J.3
  • 21
    • 80053139713 scopus 로고    scopus 로고
    • (-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a proteasome-dependent mechanism in skin cancer cells
    • S.R. Choudhury, and S. Balasubramanian (-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a proteasome-dependent mechanism in skin cancer cells Carcinogenesis 32 10 2011 1525 1532
    • (2011) Carcinogenesis , vol.32 , Issue.10 , pp. 1525-1532
    • Choudhury, S.R.1    Balasubramanian, S.2
  • 22
    • 27644597195 scopus 로고    scopus 로고
    • Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2′-deoxycytidine
    • J.C. Chuang, C.B. Yoo, and J.M. Kwan Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2′-deoxycytidine Mol Cancer Ther 4 10 2005 1515 1520
    • (2005) Mol Cancer Ther , vol.4 , Issue.10 , pp. 1515-1520
    • Chuang, J.C.1    Yoo, C.B.2    Kwan, J.M.3
  • 23
    • 51349088974 scopus 로고    scopus 로고
    • Multi-targeted prevention of cancer by sulforaphane
    • J.D. Clarke, R.H. Dashwood, and E. Ho Multi-targeted prevention of cancer by sulforaphane Cancer Lett 269 2 2008 291 304
    • (2008) Cancer Lett , vol.269 , Issue.2 , pp. 291-304
    • Clarke, J.D.1    Dashwood, R.H.2    Ho, E.3
  • 24
    • 84864645061 scopus 로고    scopus 로고
    • Pretreatment dietary intake is associated with tumor suppressor DNA methylation in head and neck squamous cell carcinomas
    • J.A. Colacino, A.E. Arthur, D.C. Dolinoy, M.A. Sartor, S.A. Duffy, and D.B. Chepeha Pretreatment dietary intake is associated with tumor suppressor DNA methylation in head and neck squamous cell carcinomas Epigenetics 7 8 2012 1 9
    • (2012) Epigenetics , vol.7 , Issue.8 , pp. 1-9
    • Colacino, J.A.1    Arthur, A.E.2    Dolinoy, D.C.3    Sartor, M.A.4    Duffy, S.A.5    Chepeha, D.B.6
  • 25
    • 0034846203 scopus 로고    scopus 로고
    • An analysis of cancer prevention by selenium
    • G.F. Combs Jr., L.C. Clark, and B.W. Turnbull An analysis of cancer prevention by selenium Biofactors 14 1-4 2001 153 159
    • (2001) Biofactors , vol.14 , Issue.14 , pp. 153-159
    • Combs, Jr.G.F.1    Clark, L.C.2    Turnbull, B.W.3
  • 26
    • 77957021225 scopus 로고    scopus 로고
    • DNA methylation and cellular reprogramming
    • D.D. De Carvalho, and J.S. You DNA methylation and cellular reprogramming Trends Cell Biol 20 10 2010 609 617
    • (2010) Trends Cell Biol , vol.20 , Issue.10 , pp. 609-617
    • De Carvalho, D.D.1    You, J.S.2
  • 28
    • 70350068690 scopus 로고    scopus 로고
    • DNA methylation and cancer diagnosis: New methods and applications
    • P. Dehan, G. Kustermans, S. Guenin, and J. Horion DNA methylation and cancer diagnosis: new methods and applications Expert Rev Mol Diagn 9 7 2009 651 657
    • (2009) Expert Rev Mol Diagn , vol.9 , Issue.7 , pp. 651-657
    • Dehan, P.1    Kustermans, G.2    Guenin, S.3    Horion, J.4
  • 29
    • 79959990071 scopus 로고    scopus 로고
    • Regulation of mammalian DNA methyltransferases: A route to new mechanisms
    • H. Denis, M.N. Ndlovu, and F. Fuks Regulation of mammalian DNA methyltransferases: a route to new mechanisms EMBO Rep 12 7 2011 647 656
    • (2011) EMBO Rep , vol.12 , Issue.7 , pp. 647-656
    • Denis, H.1    Ndlovu, M.N.2    Fuks, F.3
  • 30
    • 70149093188 scopus 로고    scopus 로고
    • Inhibition of activator protein-1 by sulforaphane involves interaction with cysteine in the cFos DNA-binding domain: Implications for chemoprevention of UVB-induced skin cancer
    • S.E. Dickinson, and T.F. Melton Inhibition of activator protein-1 by sulforaphane involves interaction with cysteine in the cFos DNA-binding domain: Implications for chemoprevention of UVB-induced skin cancer Cancer Res 69 17 2009 7103 7110
    • (2009) Cancer Res , vol.69 , Issue.17 , pp. 7103-7110
    • Dickinson, S.E.1    Melton, T.F.2
  • 31
    • 77950517628 scopus 로고    scopus 로고
    • BRD7 is a candidate tumour suppressor gene required for p53 function
    • J. Drost, and F. Mantovani BRD7 is a candidate tumour suppressor gene required for p53 function Nat Cell Biol 12 4 2010 380 389
    • (2010) Nat Cell Biol , vol.12 , Issue.4 , pp. 380-389
    • Drost, J.1    Mantovani, F.2
  • 32
    • 3242755145 scopus 로고    scopus 로고
    • Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines
    • N. Druesne, A. Pagniez, C. Mayeur, and M. Thomas Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines Carcinogenesis 25 7 2004 1227 1236
    • (2004) Carcinogenesis , vol.25 , Issue.7 , pp. 1227-1236
    • Druesne, N.1    Pagniez, A.2    Mayeur, C.3    Thomas, M.4
  • 33
    • 79952140468 scopus 로고    scopus 로고
    • Folate and cancer: How DNA damage, repair and methylation impact on colon carcinogenesis
    • S.J. Duthie Folate and cancer: how DNA damage, repair and methylation impact on colon carcinogenesis J Inherit Metab Dis 34 1 2011 101 109
    • (2011) J Inherit Metab Dis , vol.34 , Issue.1 , pp. 101-109
    • Duthie, S.J.1
  • 34
    • 79951769214 scopus 로고    scopus 로고
    • Epigenetic modifications and human pathologies: Cancer and CVD
    • S.J. Duthie Epigenetic modifications and human pathologies: cancer and CVD Proc Nutr Soc 70 1 2011 47 56
    • (2011) Proc Nutr Soc , vol.70 , Issue.1 , pp. 47-56
    • Duthie, S.J.1
  • 35
    • 0345275879 scopus 로고    scopus 로고
    • Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
    • M.Z. Fang, Y. Wang, N. Ai, and Z. Hou Tea polyphenol (-)- epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines Cancer Res 63 22 2003 7563 7570
    • (2003) Cancer Res , vol.63 , Issue.22 , pp. 7563-7570
    • Fang, M.Z.1    Wang, Y.2    Ai, N.3    Hou, Z.4
  • 36
    • 26444451123 scopus 로고    scopus 로고
    • Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy
    • M.Z. Fang, D. Chen, Y. Sun, and Z. Jin Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy Clin Cancer Res 11 19 Pt 1 2005 7033 7041
    • (2005) Clin Cancer Res , vol.11 , Issue.19 PART 1 , pp. 7033-7041
    • Fang, M.Z.1    Chen, D.2    Sun, Y.3    Jin, Z.4
  • 37
    • 2342507131 scopus 로고    scopus 로고
    • Protective effects of lycopene against ultraviolet B-induced photodamage
    • Z. Fazekas, and D. Gao Protective effects of lycopene against ultraviolet B-induced photodamage Nutr Cancer 47 2 2003 181 187
    • (2003) Nutr Cancer , vol.47 , Issue.2 , pp. 181-187
    • Fazekas, Z.1    Gao, D.2
  • 38
    • 78650019179 scopus 로고    scopus 로고
    • Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
    • M.E. Figueroa, and O. Abdel-Wahab Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation Cancer Cell 18 6 2010 553 567
    • (2010) Cancer Cell , vol.18 , Issue.6 , pp. 553-567
    • Figueroa, M.E.1    Abdel-Wahab, O.2
  • 39
    • 78650847770 scopus 로고    scopus 로고
    • Selective inhibition of BET bromodomains
    • P. Filippakopoulos, and J. Qi Selective inhibition of BET bromodomains Nature 468 7327 2010 1067 1073
    • (2010) Nature , vol.468 , Issue.7327 , pp. 1067-1073
    • Filippakopoulos, P.1    Qi, J.2
  • 40
    • 33645809586 scopus 로고    scopus 로고
    • Selenium protection from DNA damage involves a Ref1/p53/Brca1 protein complex
    • J.L. Fischer, J.K. Lancia, A. Mathur, and M.L. Smith Selenium protection from DNA damage involves a Ref1/p53/Brca1 protein complex Anticancer Res 26 2A 2006 899 904
    • (2006) Anticancer Res , vol.26 , Issue.2 , pp. 899-904
    • Fischer, J.L.1    Lancia, J.K.2    Mathur, A.3    Smith, M.L.4
  • 41
    • 78149275673 scopus 로고    scopus 로고
    • MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60
    • L.N. Fix, M. Shah, T. Efferth, and M.A. Farwell MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60 Cancer Genomics Proteomics 7 5 2010 261 277
    • (2010) Cancer Genomics Proteomics , vol.7 , Issue.5 , pp. 261-277
    • Fix, L.N.1    Shah, M.2    Efferth, T.3    Farwell, M.A.4
  • 42
    • 78650820298 scopus 로고    scopus 로고
    • Resveratrol Enhances Antitumor Activity of TRAIL in Prostate Cancer Xenografts through Activation of FOXO Transcription Factor
    • S. Ganapathy, Q. Chen, K.P. Singh, S. Shankar, and R.K. Srivastava Resveratrol Enhances Antitumor Activity of TRAIL in Prostate Cancer Xenografts through Activation of FOXO Transcription Factor PLoS One 5 12 2010 e15627
    • (2010) PLoS One , vol.5 , Issue.12 , pp. 15627
    • Ganapathy, S.1    Chen, Q.2    Singh, K.P.3    Shankar, S.4    Srivastava, R.K.5
  • 43
    • 67650892068 scopus 로고    scopus 로고
    • Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells
    • Z. Gao, Z. Xu, M.S. Hung, and Y.C. Lin Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells Anticancer Res 29 6 2009 2025 2030
    • (2009) Anticancer Res , vol.29 , Issue.6 , pp. 2025-2030
    • Gao, Z.1    Xu, Z.2    Hung, M.S.3    Lin, Y.C.4
  • 45
    • 84858600403 scopus 로고    scopus 로고
    • Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases
    • V. Gelsi-Boyer, and M. Brecqueville Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases J Hematol Oncol 5 2012 12
    • (2012) J Hematol Oncol , vol.5 , pp. 12
    • Gelsi-Boyer, V.1    Brecqueville, M.2
  • 46
    • 80052052949 scopus 로고    scopus 로고
    • Resveratrol and black tea polyphenol combination synergistically suppress mouse skin tumors growth by inhibition of activated MAPKs and p53
    • J. George, and M. Singh Resveratrol and black tea polyphenol combination synergistically suppress mouse skin tumors growth by inhibition of activated MAPKs and p53 PLoS One 6 8 2011 e23395
    • (2011) PLoS One , vol.6 , Issue.8 , pp. 23395
    • George, J.1    Singh, M.2
  • 48
    • 0033577044 scopus 로고    scopus 로고
    • Tomatoes, tomato-based products, lycopene, and cancer: Review of the epidemiologic literature
    • E. Giovannucci Tomatoes, tomato-based products, lycopene, and cancer: review of the epidemiologic literature J Natl Cancer Inst 91 4 1999 317 331
    • (1999) J Natl Cancer Inst , vol.91 , Issue.4 , pp. 317-331
    • Giovannucci, E.1
  • 49
    • 33847047461 scopus 로고    scopus 로고
    • Epigenetics: A landscape takes shape
    • A.D. Goldberg, C.D. Allis, and E. Bernstein Epigenetics: a landscape takes shape Cell 128 4 2007 635 638
    • (2007) Cell , vol.128 , Issue.4 , pp. 635-638
    • Goldberg, A.D.1    Allis, C.D.2    Bernstein, E.3
  • 50
    • 64849110824 scopus 로고    scopus 로고
    • EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression
    • B. Gu, Q. Ding, G. Xia, and Z. Fang EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression Oncol Rep 21 3 2009 635 640
    • (2009) Oncol Rep , vol.21 , Issue.3 , pp. 635-640
    • Gu, B.1    Ding, Q.2    Xia, G.3    Fang, Z.4
  • 51
    • 79953797962 scopus 로고    scopus 로고
    • Mutation and loss of expression of ARID1A in uterine low-grade endometrioid carcinoma
    • B. Guan, and T.L. Mao Mutation and loss of expression of ARID1A in uterine low-grade endometrioid carcinoma Am J Surg Pathol 35 5 2011 625 632
    • (2011) Am J Surg Pathol , vol.35 , Issue.5 , pp. 625-632
    • Guan, B.1    Mao, T.L.2
  • 52
    • 80052009897 scopus 로고    scopus 로고
    • Epigenetic diet: Impact on the epigenome and cancer
    • T.M. Hardy, and T.O. Tollefsbol Epigenetic diet: impact on the epigenome and cancer Epigenomics 3 4 2011 503 518
    • (2011) Epigenomics , vol.3 , Issue.4 , pp. 503-518
    • Hardy, T.M.1    Tollefsbol, T.O.2
  • 53
    • 80053622239 scopus 로고    scopus 로고
    • Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency
    • R.D. Hawkins, G.C. Hon, C. Yang, J.E. Antosiewicz-Bourget, L.K. Lee, and Q.M. Ngo Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency Cell Res 21 10 2011 1393 1409
    • (2011) Cell Res , vol.21 , Issue.10 , pp. 1393-1409
    • Hawkins, R.D.1    Hon, G.C.2    Yang, C.3    Antosiewicz-Bourget, J.E.4    Lee, L.K.5    Ngo, Q.M.6
  • 54
    • 51349096457 scopus 로고    scopus 로고
    • Multi-targeted therapy of cancer by ellagitannins
    • D. Heber Multi-targeted therapy of cancer by ellagitannins Cancer Lett 269 2 2008 262 268
    • (2008) Cancer Lett , vol.269 , Issue.2 , pp. 262-268
    • Heber, D.1
  • 55
    • 84862274000 scopus 로고    scopus 로고
    • Dietary factors and epigenetic regulation for prostate cancer prevention
    • E. Ho, L.M. Beaver, D.E. Williams, and R.H. Dashwood Dietary factors and epigenetic regulation for prostate cancer prevention Adv Nutr 2 6 2011 497 510
    • (2011) Adv Nutr , vol.2 , Issue.6 , pp. 497-510
    • Ho, E.1    Beaver, L.M.2    Williams, D.E.3    Dashwood, R.H.4
  • 56
    • 79960909421 scopus 로고    scopus 로고
    • De novo nonsense mutations in ASXL1 cause Bohring-Opitz syndrome
    • A. Hoischen, and B.W. van Bon De novo nonsense mutations in ASXL1 cause Bohring-Opitz syndrome Nat Genet 43 8 2011 729 731
    • (2011) Nat Genet , vol.43 , Issue.8 , pp. 729-731
    • Hoischen, A.1    Van Bon, B.W.2
  • 57
    • 77649177097 scopus 로고    scopus 로고
    • Predictive chromatin signatures in the mammalian genome
    • G.C. Hon, R.D. Hawkins, and B. Ren Predictive chromatin signatures in the mammalian genome Hum Mol Genet 18 R2 2009 R195 R201
    • (2009) Hum Mol Genet , vol.18 , Issue.2
    • Hon, G.C.1    Hawkins, R.D.2    Ren, B.3
  • 58
    • 12144290788 scopus 로고    scopus 로고
    • Isoflavones stimulate estrogen receptor-mediated core histone acetylation
    • T. Hong, T. Nakagawa, W. Pan, and M.Y. Kim Isoflavones stimulate estrogen receptor-mediated core histone acetylation Biochem Biophys Res Commun 317 1 2004 259 264
    • (2004) Biochem Biophys Res Commun , vol.317 , Issue.1 , pp. 259-264
    • Hong, T.1    Nakagawa, T.2    Pan, W.3    Kim, M.Y.4
  • 59
    • 34447501969 scopus 로고    scopus 로고
    • Green tea polyphenol induces caspase 14 in epidermal keratinocytes via MAPK pathways and reduces psoriasiform lesions in the flaky skin mouse model
    • S. Hsu, and D. Dickinson Green tea polyphenol induces caspase 14 in epidermal keratinocytes via MAPK pathways and reduces psoriasiform lesions in the flaky skin mouse model Exp Dermatol 16 8 2007 678 684
    • (2007) Exp Dermatol , vol.16 , Issue.8 , pp. 678-684
    • Hsu, S.1    Dickinson, D.2
  • 60
    • 67449147110 scopus 로고    scopus 로고
    • Targeting DNA methylation
    • J.P. Issa, and H.M. Kantarjian Targeting DNA methylation Clin Cancer Res 15 12 2009 3938 3946
    • (2009) Clin Cancer Res , vol.15 , Issue.12 , pp. 3938-3946
    • Issa, J.P.1    Kantarjian, H.M.2
  • 61
    • 77649196362 scopus 로고    scopus 로고
    • Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs
    • A. Izzotti, G.A. Calin, V.E. Steele, and C. Cartiglia Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs Cancer Prev Res (Phila) 3 1 2010 62 72
    • (2010) Cancer Prev Res (Phila) , vol.3 , Issue.1 , pp. 62-72
    • Izzotti, A.1    Calin, G.A.2    Steele, V.E.3    Cartiglia, C.4
  • 62
    • 77952304948 scopus 로고    scopus 로고
    • Modulation of microRNA expression by budesonide, phenethyl isothiocyanate and cigarette smoke in mouse liver and lung
    • A. Izzotti, P. Larghero, C. Cartiglia, and M. Longobardi Modulation of microRNA expression by budesonide, phenethyl isothiocyanate and cigarette smoke in mouse liver and lung Carcinogenesis 31 5 2010 894 901
    • (2010) Carcinogenesis , vol.31 , Issue.5 , pp. 894-901
    • Izzotti, A.1    Larghero, P.2    Cartiglia, C.3    Longobardi, M.4
  • 63
    • 33846581497 scopus 로고    scopus 로고
    • Loss of imprinting and cancer
    • P. Jelinic, and P. Shaw Loss of imprinting and cancer J Pathol 211 3 2007 261 268
    • (2007) J Pathol , vol.211 , Issue.3 , pp. 261-268
    • Jelinic, P.1    Shaw, P.2
  • 65
    • 77956408743 scopus 로고    scopus 로고
    • 3,3'-Diindolylmethane negatively regulates Cdc25A and induces a G2/M arrest by modulation of microRNA 21 in human breast cancer cells
    • Y. Jin, X. Zou, and X. Feng 3,3'-Diindolylmethane negatively regulates Cdc25A and induces a G2/M arrest by modulation of microRNA 21 in human breast cancer cells Anticancer Drugs 21 9 2010 814 822
    • (2010) Anticancer Drugs , vol.21 , Issue.9 , pp. 814-822
    • Jin, Y.1    Zou, X.2    Feng, X.3
  • 66
    • 0037068378 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • P.A. Jones DNA methylation and cancer Oncogene 21 35 2002 5358 5360
    • (2002) Oncogene , vol.21 , Issue.35 , pp. 5358-5360
    • Jones, P.A.1
  • 67
    • 77957731999 scopus 로고    scopus 로고
    • Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma
    • S. Jones, and T.L. Wang Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma Science 330 2010 228 231
    • (2010) Science , vol.330 , pp. 228-231
    • Jones, S.1    Wang, T.L.2
  • 68
    • 0037456636 scopus 로고    scopus 로고
    • Mutation of the DNA methyltransferase (DNMT) 1 gene in human colorectal cancers
    • Y. Kanai, and S. Ushijima Mutation of the DNA methyltransferase (DNMT) 1 gene in human colorectal cancers Cancer Lett 192 1 2003 75 82
    • (2003) Cancer Lett , vol.192 , Issue.1 , pp. 75-82
    • Kanai, Y.1    Ushijima, S.2
  • 69
    • 15744370742 scopus 로고    scopus 로고
    • Curcumin-induced histone hypoacetylation: The role of reactive oxygen species
    • J. Kang, and J. Chen Curcumin-induced histone hypoacetylation: The role of reactive oxygen species Biochem Pharmacol 69 8 2005 1205 1213
    • (2005) Biochem Pharmacol , vol.69 , Issue.8 , pp. 1205-1213
    • Kang, J.1    Chen, J.2
  • 70
    • 34247136212 scopus 로고    scopus 로고
    • Green tea and skin cancer: Photoimmunology, angiogenesis and DNA repair
    • S. Katiyar, and C.A. Elmets Green tea and skin cancer: Photoimmunology, angiogenesis and DNA repair J Nutr Biochem 18 5 2007 287 296
    • (2007) J Nutr Biochem , vol.18 , Issue.5 , pp. 287-296
    • Katiyar, S.1    Elmets, C.A.2
  • 71
    • 49549087270 scopus 로고    scopus 로고
    • Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells
    • K. Kato, N.K. Long, H. Makita, and M. Toida Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells Br J Cancer 99 4 2008 647 654
    • (2008) Br J Cancer , vol.99 , Issue.4 , pp. 647-654
    • Kato, K.1    Long, N.K.2    Makita, H.3    Toida, M.4
  • 72
    • 46049103996 scopus 로고    scopus 로고
    • Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells
    • N. Kikuno, H. Shiina, S. Urakami, and K. Kawamoto Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells Int J Cancer 123 3 2008 552 560
    • (2008) Int J Cancer , vol.123 , Issue.3 , pp. 552-560
    • Kikuno, N.1    Shiina, H.2    Urakami, S.3    Kawamoto, K.4
  • 73
    • 34250197957 scopus 로고    scopus 로고
    • Folate and colorectal cancer: An evidence-based critical review
    • Y.I. Kim Folate and colorectal cancer: an evidence-based critical review Mol Nutr Food Res 51 3 2007 267 292
    • (2007) Mol Nutr Food Res , vol.51 , Issue.3 , pp. 267-292
    • Kim, Y.I.1
  • 74
    • 77955439008 scopus 로고    scopus 로고
    • Chemoprevention of head and neck cancer with green tea polyphenols
    • J.W. Kim, A.R. Amin, and D.M. Shin Chemoprevention of head and neck cancer with green tea polyphenols Cancer Prev Res 3 8 2010 900 909
    • (2010) Cancer Prev Res , vol.3 , Issue.8 , pp. 900-909
    • Kim, J.W.1    Amin, A.R.2    Shin, D.M.3
  • 75
    • 79954613030 scopus 로고    scopus 로고
    • Genetic and expressional alterations of CHD genes in gastric and colorectal cancers
    • M.S. Kim, and N.G. Chung Genetic and expressional alterations of CHD genes in gastric and colorectal cancers Histopathology 58 5 2011 660 668
    • (2011) Histopathology , vol.58 , Issue.5 , pp. 660-668
    • Kim, M.S.1    Chung, N.G.2
  • 76
    • 39749140314 scopus 로고    scopus 로고
    • Modulation of gene methylation by genistein or lycopene in breast cancer cells
    • A. King-Batoon, J.M. Leszczynska, and C.B. Klein Modulation of gene methylation by genistein or lycopene in breast cancer cells Environ Mol Mutagen 49 1 2008 36 45
    • (2008) Environ Mol Mutagen , vol.49 , Issue.1 , pp. 36-45
    • King-Batoon, A.1    Leszczynska, J.M.2    Klein, C.B.3
  • 77
    • 84855833517 scopus 로고    scopus 로고
    • Genomics-based identification of molecular mechanisms behind the cancer preventive action of phytochemicals: Potential and challenges
    • T.M. Kok, S.G. Breda, and B.JJ Genomics-based identification of molecular mechanisms behind the cancer preventive action of phytochemicals: potential and challenges Curr Pharm Biotechnol 13 1 2012 255 264
    • (2012) Curr Pharm Biotechnol , vol.13 , Issue.1 , pp. 255-264
    • Kok, T.M.1    Breda, S.G.2
  • 78
    • 0022759227 scopus 로고
    • Environmental factors in cancer etiology
    • C.E. Kupchella Environmental factors in cancer etiology Semin Oncol Nurs 2 3 1986 161 169
    • (1986) Semin Oncol Nurs , vol.2 , Issue.3 , pp. 161-169
    • Kupchella, C.E.1
  • 79
    • 79952740874 scopus 로고    scopus 로고
    • Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells
    • C. Kürbitz, D. Heise, and T. Redmer Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells Cancer Sci 102 4 2011 728 734
    • (2011) Cancer Sci , vol.102 , Issue.4 , pp. 728-734
    • Kürbitz, C.1    Heise, D.2    Redmer, T.3
  • 80
    • 77950586365 scopus 로고    scopus 로고
    • DNA methyltransferases and methyl-binding proteins of mammals
    • J. Lan, S. Hua, X. He, and Y. Zhang DNA methyltransferases and methyl-binding proteins of mammals Acta Biochim Biophys Sin 42 4 2010 243 252
    • (2010) Acta Biochim Biophys Sin , vol.42 , Issue.4 , pp. 243-252
    • Lan, J.1    Hua, S.2    He, X.3    Zhang, Y.4
  • 81
    • 0033173102 scopus 로고    scopus 로고
    • Increased acetylation of histones induced by diallyl disulfide and structurally related molecules
    • M.A. Lea, V.M. Randolph, and M. Patel Increased acetylation of histones induced by diallyl disulfide and structurally related molecules Int J Oncol 15 2 1999 347 352
    • (1999) Int J Oncol , vol.15 , Issue.2 , pp. 347-352
    • Lea, M.A.1    Randolph, V.M.2    Patel, M.3
  • 82
    • 0035876964 scopus 로고    scopus 로고
    • Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate
    • M.A. Lea, V.M. Randolph, J.E. Lee, and C. desBordes Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate Int J Cancer 92 6 2001 784 789
    • (2001) Int J Cancer , vol.92 , Issue.6 , pp. 784-789
    • Lea, M.A.1    Randolph, V.M.2    Lee, J.E.3    Desbordes, C.4
  • 83
    • 0036437194 scopus 로고    scopus 로고
    • Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine
    • M.A. Lea, M. Rasheed, V.M. Randolph, and F. Khan Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine Nutr Cancer 43 1 2002 90 102
    • (2002) Nutr Cancer , vol.43 , Issue.1 , pp. 90-102
    • Lea, M.A.1    Rasheed, M.2    Randolph, V.M.3    Khan, F.4
  • 84
    • 25144507259 scopus 로고    scopus 로고
    • Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids
    • W.J. Lee, J.Y. Shim, and B.T. Zhu Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids Mol Pharmacol 68 4 2005 1018 1030
    • (2005) Mol Pharmacol , vol.68 , Issue.4 , pp. 1018-1030
    • Lee, W.J.1    Shim, J.Y.2    Zhu, B.T.3
  • 85
    • 78651347259 scopus 로고    scopus 로고
    • Quercetin induces FasL-related apoptosis, in part, through promotion of histone H3 acetylation in human leukemia HL-60 cells
    • W.J. Lee, Y.R. Chen, and T.H. Tseng Quercetin induces FasL-related apoptosis, in part, through promotion of histone H3 acetylation in human leukemia HL-60 cells Oncol Rep 25 2 2011 583 591
    • (2011) Oncol Rep , vol.25 , Issue.2 , pp. 583-591
    • Lee, W.J.1    Chen, Y.R.2    Tseng, T.H.3
  • 86
    • 78649906060 scopus 로고    scopus 로고
    • DNMT3A mutations in acute myeloid leukemia
    • T.J. Ley, and L. Ding DNMT3A mutations in acute myeloid leukemia N Engl J Med 363 25 2010 2424 2433
    • (2010) N Engl J Med , vol.363 , Issue.25 , pp. 2424-2433
    • Ley, T.J.1    Ding, L.2
  • 87
    • 77954623392 scopus 로고    scopus 로고
    • Elevated levels of selenium in the typical diet of Amazonian riverside populations
    • M. Lemire, M. Fillion, F. Barbosa Jr., J.R. Guimaraes, and D. Mergler Elevated levels of selenium in the typical diet of Amazonian riverside populations Sci Total Environ 408 19 2010 4076 4084
    • (2010) Sci Total Environ , vol.408 , Issue.19 , pp. 4076-4084
    • Lemire, M.1    Fillion, M.2    Barbosa, Jr.F.3    Guimaraes, J.R.4    Mergler, D.5
  • 88
    • 84861937510 scopus 로고    scopus 로고
    • Silencing of Wnt5a during colon cancer metastasis involves histone modifications
    • Q. Li, and H. Chen Silencing of Wnt5a during colon cancer metastasis involves histone modifications Epigenetics 7 6 2012 551 558
    • (2012) Epigenetics , vol.7 , Issue.6 , pp. 551-558
    • Li, Q.1    Chen, H.2
  • 89
    • 69249096109 scopus 로고    scopus 로고
    • Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells
    • Y. Li, T.G. VandenBoom II, D. Kong, and Z. Wang Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells Cancer Res 69 16 2009 6704 6712
    • (2009) Cancer Res , vol.69 , Issue.16 , pp. 6704-6712
    • Li, Y.1    Vandenboom, I.I.T.G.2    Kong, D.3    Wang, Z.4
  • 90
    • 76549093815 scopus 로고    scopus 로고
    • Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class i histone deacetylases
    • Y. Li, X. Li, and B. Guo Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases Cancer Res 70 2 2010 646 654
    • (2010) Cancer Res , vol.70 , Issue.2 , pp. 646-654
    • Li, Y.1    Li, X.2    Guo, B.3
  • 91
    • 76749152907 scopus 로고    scopus 로고
    • MiR-146a suppresses invasion of pancreatic cancer cells
    • Y. Li, T.G. VandenBoom II, Z. Wang, and D. Kong miR-146a suppresses invasion of pancreatic cancer cells Cancer Res 70 4 2010 1486 1495
    • (2010) Cancer Res , vol.70 , Issue.4 , pp. 1486-1495
    • Li, Y.1    Vandenboom, I.I.T.G.2    Wang, Z.3    Kong, D.4
  • 92
    • 80052271807 scopus 로고    scopus 로고
    • Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma
    • M. Li, and H. Zhao Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma Nat Genet 43 9 2011 828 829
    • (2011) Nat Genet , vol.43 , Issue.9 , pp. 828-829
    • Li, M.1    Zhao, H.2
  • 93
    • 84860006823 scopus 로고    scopus 로고
    • Dietary and lifestyle factors of DNA methylation
    • U. Lim, and M.A. Song Dietary and lifestyle factors of DNA methylation Methods Mol Biol 863 2012 359 376
    • (2012) Methods Mol Biol , vol.863 , pp. 359-376
    • Lim, U.1    Song, M.A.2
  • 94
    • 18744403080 scopus 로고    scopus 로고
    • Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation
    • H.L. Liu, Y. Chen, G.H. Cui, and J.F. Zhou Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation Acta Pharmacol Sin 26 5 2005 603 609
    • (2005) Acta Pharmacol Sin , vol.26 , Issue.5 , pp. 603-609
    • Liu, H.L.1    Chen, Y.2    Cui, G.H.3    Zhou, J.F.4
  • 95
    • 18744403080 scopus 로고    scopus 로고
    • Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation
    • H.L. Liu, Y. Chen, G.H. Cui, and J.F. Zhou Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation Acta Pharmacol Sin 26 5 2005 603 609
    • (2005) Acta Pharmacol Sin , vol.26 , Issue.5 , pp. 603-609
    • Liu, H.L.1    Chen, Y.2    Cui, G.H.3    Zhou, J.F.4
  • 96
  • 97
    • 84858796262 scopus 로고    scopus 로고
    • IDH mutation impairs histone demethylation and results in a block to cell differentiation
    • C. Lu, and P.S. Ward IDH mutation impairs histone demethylation and results in a block to cell differentiation Nature 483 2012 474 478
    • (2012) Nature , vol.483 , pp. 474-478
    • Lu, C.1    Ward, P.S.2
  • 98
    • 78649669021 scopus 로고    scopus 로고
    • Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation
    • R.U. Lukacs, and S. Memarzadeh Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation Cell Stem Cell 7 6 2010 682 693
    • (2010) Cell Stem Cell , vol.7 , Issue.6 , pp. 682-693
    • Lukacs, R.U.1    Memarzadeh, S.2
  • 99
    • 0242539832 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations as hallmarks of the intricate road to cancer
    • M. Macaluso, M.G. Paggi, and A. Giordano Genetic and epigenetic alterations as hallmarks of the intricate road to cancer Oncogene 22 42 2003 6472 6478
    • (2003) Oncogene , vol.22 , Issue.42 , pp. 6472-6478
    • MacAluso, M.1    Paggi, M.G.2    Giordano, A.3
  • 100
    • 64349112758 scopus 로고    scopus 로고
    • BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer
    • S. Majid, A.A. Dar, A.E. Ahmad, and H. Hirata BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer Carcinogenesis 30 4 2009 662 670
    • (2009) Carcinogenesis , vol.30 , Issue.4 , pp. 662-670
    • Majid, S.1    Dar, A.A.2    Ahmad, A.E.3    Hirata, H.4
  • 101
    • 77950822746 scopus 로고    scopus 로고
    • Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer
    • S. Majid, A.A. Dar, S. Saini, and Y. Chen Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer Cancer Res 70 7 2010 2809 2818
    • (2010) Cancer Res , vol.70 , Issue.7 , pp. 2809-2818
    • Majid, S.1    Dar, A.A.2    Saini, S.3    Chen, Y.4
  • 102
    • 74549216395 scopus 로고    scopus 로고
    • Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer
    • S. Majid, A.A. Dar, V. Shahryari, and H. Hirata Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer Cancer 116 1 2010 66 76
    • (2010) Cancer , vol.116 , Issue.1 , pp. 66-76
    • Majid, S.1    Dar, A.A.2    Shahryari, V.3    Hirata, H.4
  • 103
    • 42349103444 scopus 로고    scopus 로고
    • Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification
    • S. Majid, N. Kikuno, J. Nelles, and E. Noonan Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification Cancer Res 68 8 2008 2736 2744
    • (2008) Cancer Res , vol.68 , Issue.8 , pp. 2736-2744
    • Majid, S.1    Kikuno, N.2    Nelles, J.3    Noonan, E.4
  • 104
    • 33746127271 scopus 로고    scopus 로고
    • Curcumin is an inhibitor of p300 histone acetylatransferase
    • M.G. Marcu, Y.J. Jung, S. Lee, and E.J. Chung Curcumin is an inhibitor of p300 histone acetylatransferase Med Chem 2 2 2006 169 174
    • (2006) Med Chem , vol.2 , Issue.2 , pp. 169-174
    • Marcu, M.G.1    Jung, Y.J.2    Lee, S.3    Chung, E.J.4
  • 105
    • 63449140634 scopus 로고    scopus 로고
    • The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways
    • L. Mattera, and F. Escaffit The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways Oncogene 28 12 2009 1506 1517
    • (2009) Oncogene , vol.28 , Issue.12 , pp. 1506-1517
    • Mattera, L.1    Escaffit, F.2
  • 106
    • 79958002242 scopus 로고    scopus 로고
    • Natural products as DNA methyltransferase inhibitors: A computer-aided discovery approach
    • J.L. Medina-Franco, F. López-Vallejo, D. Kuck, and F. Lyko Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach Mol Divers 15 2 2011 293 304
    • (2011) Mol Divers , vol.15 , Issue.2 , pp. 293-304
    • Medina-Franco, J.L.1    López-Vallejo, F.2    Kuck, D.3    Lyko, F.4
  • 107
    • 77955352742 scopus 로고    scopus 로고
    • Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines
    • S.M. Meeran, S.N. Patel, and T.O. Tollefsbol Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines PLoS One 5 7 2010 e11457
    • (2010) PLoS One , vol.5 , Issue.7 , pp. 11457
    • Meeran, S.M.1    Patel, S.N.2    Tollefsbol, T.O.3
  • 108
    • 77957154350 scopus 로고    scopus 로고
    • Throwing the cancer switch: Reciprocal roles of polycomb and trithorax proteins
    • A.A. Mills Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteins Nat Rev Cancer 10 10 2010 669 682
    • (2010) Nat Rev Cancer , vol.10 , Issue.10 , pp. 669-682
    • Mills, A.A.1
  • 109
    • 34547799203 scopus 로고    scopus 로고
    • Cancer genetics of epigenetic genes
    • A. Miremadi, and M.Z. Oestergaard Cancer genetics of epigenetic genes Hum Mol Genet 16 2007 28 49
    • (2007) Hum Mol Genet , vol.16 , pp. 28-49
    • Miremadi, A.1    Oestergaard, M.Z.2
  • 110
    • 80052029516 scopus 로고    scopus 로고
    • Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
    • R.D. Morin, and M. Mendez-Lago Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma Nature 476 7360 2011 298 303
    • (2011) Nature , vol.476 , Issue.7360 , pp. 298-303
    • Morin, R.D.1    Mendez-Lago, M.2
  • 111
    • 79955648469 scopus 로고    scopus 로고
    • Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer
    • G. Mudduluru, J.N. George-William, S. Muppala, and I.A. Asangani Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer Biosci Rep 31 3 2011 185 197
    • (2011) Biosci Rep , vol.31 , Issue.3 , pp. 185-197
    • Mudduluru, G.1    George-William, J.N.2    Muppala, S.3    Asangani, I.A.4
  • 112
    • 67650886038 scopus 로고    scopus 로고
    • Black tea polyphenols target matrix metalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model
    • R.S. Murugan, G. Vinothini, Y. Hara, and S. Nagini Black tea polyphenols target matrix metalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model Anticancer Res 29 6 2009 2301 2305
    • (2009) Anticancer Res , vol.29 , Issue.6 , pp. 2301-2305
    • Murugan, R.S.1    Vinothini, G.2    Hara, Y.3    Nagini, S.4
  • 113
    • 4143130097 scopus 로고    scopus 로고
    • A novel mechanism of chemoprotection by sulforaphane: Inhibition of histone deacetylase
    • M.C. Myzak, P.A. Karplus, F.L. Chung, and R.H. Dashwood A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase Cancer Res 64 16 2004 5767 5774
    • (2004) Cancer Res , vol.64 , Issue.16 , pp. 5767-5774
    • Myzak, M.C.1    Karplus, P.A.2    Chung, F.L.3    Dashwood, R.H.4
  • 114
    • 33645825587 scopus 로고    scopus 로고
    • Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice
    • M.C. Myzak, W.M. Dashwood, G.A. Orner, and E. Ho Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice FASEB J 20 3 2006 506 508
    • (2006) FASEB J , vol.20 , Issue.3 , pp. 506-508
    • Myzak, M.C.1    Dashwood, W.M.2    Orner, G.A.3    Ho, E.4
  • 115
    • 33645324413 scopus 로고    scopus 로고
    • Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells
    • M.C. Myzak, K. Hardin, R. Wang, and R.H. Dashwood Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells Carcinogenesis 27 4 2006 811 819
    • (2006) Carcinogenesis , vol.27 , Issue.4 , pp. 811-819
    • Myzak, M.C.1    Hardin, K.2    Wang, R.3    Dashwood, R.H.4
  • 116
    • 33846838750 scopus 로고    scopus 로고
    • Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects
    • M.C. Myzak, P. Tong, W.M. Dashwood, and R.H. Dashwood Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects Exp Biol Med (Maywood) 232 2 2007 227 234
    • (2007) Exp Biol Med (Maywood) , vol.232 , Issue.2 , pp. 227-234
    • Myzak, M.C.1    Tong, P.2    Dashwood, W.M.3    Dashwood, R.H.4
  • 117
    • 79953692105 scopus 로고    scopus 로고
    • (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells
    • V. Nandakumar, and M. Vaid (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells Carcinogenesis 32 4 2011 537 544
    • (2011) Carcinogenesis , vol.32 , Issue.4 , pp. 537-544
    • Nandakumar, V.1    Vaid, M.2
  • 119
    • 77951225012 scopus 로고    scopus 로고
    • Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells
    • M. Pandey, S. Shukla, and S. Gupta Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells Int J Cancer 126 11 2010 2520 2533
    • (2010) Int J Cancer , vol.126 , Issue.11 , pp. 2520-2533
    • Pandey, M.1    Shukla, S.2    Gupta, S.3
  • 120
    • 84855826512 scopus 로고    scopus 로고
    • MicroRNAs, diet, and cancer: New mechanistic insights on the epigenetic actions of phytochemicals
    • M.A. Parasramka, E. Ho, D.E. Williams, and D. RH MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals Mol Carcinog 51 3 2012 213 230
    • (2012) Mol Carcinog , vol.51 , Issue.3 , pp. 213-230
    • Parasramka, M.A.1    Ho, E.2    Williams, D.E.3    Rh, D.4
  • 121
    • 70949103350 scopus 로고    scopus 로고
    • Modulation of microRNA associated with ovarian cancer cells by genistein
    • L.P. Parker, D.D. Taylor, J. Kesterson, and D.S. Metzinger Modulation of microRNA associated with ovarian cancer cells by genistein Eur J Gynaecol Oncol 30 6 2009 616 621
    • (2009) Eur J Gynaecol Oncol , vol.30 , Issue.6 , pp. 616-621
    • Parker, L.P.1    Taylor, D.D.2    Kesterson, J.3    Metzinger, D.S.4
  • 122
    • 34147135143 scopus 로고    scopus 로고
    • Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines
    • A. Pledgie-Tracy, M.D. Sobolewski, and N.E. Davidson Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines Mol Cancer Ther 6 3 2007 1013 1021
    • (2007) Mol Cancer Ther , vol.6 , Issue.3 , pp. 1013-1021
    • Pledgie-Tracy, A.1    Sobolewski, M.D.2    Davidson, N.E.3
  • 123
    • 30944437615 scopus 로고    scopus 로고
    • Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency
    • I.P. Pogribny, S.A. Ross, C. Wise, M. Pogribna, E.A. Jones, and V.P. Tryndyak Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency Mutat Res 593 1-2 2006 80 87
    • (2006) Mutat Res , vol.593 , Issue.12 , pp. 80-87
    • Pogribny, I.P.1    Ross, S.A.2    Wise, C.3    Pogribna, M.4    Jones, E.A.5    Tryndyak, V.P.6
  • 124
    • 0028224866 scopus 로고
    • Methyl group deficiency in hepatocarcinogenesis
    • L.A. Poirier Methyl group deficiency in hepatocarcinogenesis Drug Metab Rev 26 1-2 1994 185 199
    • (1994) Drug Metab Rev , vol.26 , Issue.12 , pp. 185-199
    • Poirier, L.A.1
  • 125
    • 79951915882 scopus 로고    scopus 로고
    • The flavonoid quercetin modulates the hallmark capabilities of hamster buccal pouch tumors
    • R.V. Priyadarsini, G. Vinothini, R.S. Murugan, and P. Manikandan The flavonoid quercetin modulates the hallmark capabilities of hamster buccal pouch tumors Nutr Cancer 63 2 2011 218 226
    • (2011) Nutr Cancer , vol.63 , Issue.2 , pp. 218-226
    • Priyadarsini, R.V.1    Vinothini, G.2    Murugan, R.S.3    Manikandan, P.4
  • 126
    • 61649113446 scopus 로고    scopus 로고
    • Soy isoflavones have an anti-estrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women
    • W. Qin, W. Zhu, H. Shi, and J.E. Hewett Soy isoflavones have an anti-estrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women Nutr Cancer 61 2 2009 238 244
    • (2009) Nutr Cancer , vol.61 , Issue.2 , pp. 238-244
    • Qin, W.1    Zhu, W.2    Shi, H.3    Hewett, J.E.4
  • 127
    • 84860238020 scopus 로고    scopus 로고
    • Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells
    • P. Rajendran, E. Ho, D.E. Williams, and R.H. Dashwood Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells Clin Epigenetics 3 1 2011 4
    • (2011) Clin Epigenetics , vol.3 , Issue.1 , pp. 4
    • Rajendran, P.1    Ho, E.2    Williams, D.E.3    Dashwood, R.H.4
  • 128
    • 24044552286 scopus 로고    scopus 로고
    • Experimental study on anti-neoplastic activity of epigallocatechin-3- gallate to digestive tract carcinomas
    • Z.H. Ran, J. Zou, and S.D. Xiao Experimental study on anti-neoplastic activity of epigallocatechin-3-gallate to digestive tract carcinomas Chin Med J (Engl) 118 16 2005 1330 1337
    • (2005) Chin Med J (Engl) , vol.118 , Issue.16 , pp. 1330-1337
    • Ran, Z.H.1    Zou, J.2    Xiao, S.D.3
  • 129
    • 0032513272 scopus 로고    scopus 로고
    • Inhibitory effect of selenomethionine on the growth of three selected human tumor cell lines
    • C. Redman, J.A. Scott, A.T. Baines, J.L. Basye, L.C. Clark, and C. Calley Inhibitory effect of selenomethionine on the growth of three selected human tumor cell lines Cancer Lett 125 1-2 1998 103 110
    • (1998) Cancer Lett , vol.125 , Issue.12 , pp. 103-110
    • Redman, C.1    Scott, J.A.2    Baines, A.T.3    Basye, J.L.4    Clark, L.C.5    Calley, C.6
  • 130
    • 33646354640 scopus 로고    scopus 로고
    • A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition
    • S. Ropero, and M.F. Fraga A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition Nat Genet 38 5 2006 566 569
    • (2006) Nat Genet , vol.38 , Issue.5 , pp. 566-569
    • Ropero, S.1    Fraga, M.F.2
  • 131
    • 80054787805 scopus 로고    scopus 로고
    • Targeting histone demethylases: A new avenue for the fight against cancer
    • D. Rotili Targeting histone demethylases: A new avenue for the fight against cancer Genes Cancer 2 2011 663 679
    • (2011) Genes Cancer , vol.2 , pp. 663-679
    • Rotili, D.1
  • 132
    • 77954675751 scopus 로고    scopus 로고
    • Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer
    • S.K. Roy, R.K. Srivastava, and S. Shankar Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer J Mol Signal 5 2010 10
    • (2010) J Mol Signal , vol.5 , pp. 10
    • Roy, S.K.1    Srivastava, R.K.2    Shankar, S.3
  • 133
    • 80053199541 scopus 로고    scopus 로고
    • Resveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors
    • S.K. Roy, Q. Chen, J. Fu, S. Shankar, and R.K. Srivastava Resveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors PLoS One 6 9 2011 e25166
    • (2011) PLoS One , vol.6 , Issue.9 , pp. 25166
    • Roy, S.K.1    Chen, Q.2    Fu, J.3    Shankar, S.4    Srivastava, R.K.5
  • 134
    • 34247872831 scopus 로고    scopus 로고
    • Quercetin inhibits TNF-induced NF-kappaB transcription factor recruitment to proinflammatory gene promoters in murine intestinal epithelial cells
    • P.A. Ruiz, A. Braune, G. Hölzlwimmer, and L. Quintanilla-Fend Quercetin inhibits TNF-induced NF-kappaB transcription factor recruitment to proinflammatory gene promoters in murine intestinal epithelial cells J Nutr 137 5 2007 1208 1215
    • (2007) J Nutr , vol.137 , Issue.5 , pp. 1208-1215
    • Ruiz, P.A.1    Braune, A.2    Hölzlwimmer, G.3    Quintanilla-Fend, L.4
  • 135
    • 34247860920 scopus 로고    scopus 로고
    • Mechanisms of disease: Methyl-binding domain proteins as potential therapeutic targets in cancer
    • O.J. Sansom, and K. Maddison Mechanisms of disease: Methyl-binding domain proteins as potential therapeutic targets in cancer Nat Clin Pract Oncol 4 5 2007 305 315
    • (2007) Nat Clin Pract Oncol , vol.4 , Issue.5 , pp. 305-315
    • Sansom, O.J.1    Maddison, K.2
  • 136
    • 0036130279 scopus 로고    scopus 로고
    • Resveratrol and cancer: A review
    • J.F. Savouret, and M. Quesne Resveratrol and cancer: a review Biomed Pharmacother 56 2 2002 84 87
    • (2002) Biomed Pharmacother , vol.56 , Issue.2 , pp. 84-87
    • Savouret, J.F.1    Quesne, M.2
  • 137
    • 79955710308 scopus 로고    scopus 로고
    • Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane
    • C.L. Saw, and M.T. Huang Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane Mol Carcinog 50 6 2011 479 486
    • (2011) Mol Carcinog , vol.50 , Issue.6 , pp. 479-486
    • Saw, C.L.1    Huang, M.T.2
  • 138
    • 77957346763 scopus 로고    scopus 로고
    • Histone modifications and cancer
    • C. Sawan, and Z. Herceg Histone modifications and cancer Adv Genet 70 2010 57 85
    • (2010) Adv Genet , vol.70 , pp. 57-85
    • Sawan, C.1    Herceg, Z.2
  • 139
    • 58149234401 scopus 로고    scopus 로고
    • Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis
    • S. Shankar, and S. Ganapathy Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis Clin Cancer Res 14 21 2008 6855 6866
    • (2008) Clin Cancer Res , vol.14 , Issue.21 , pp. 6855-6866
    • Shankar, S.1    Ganapathy, S.2
  • 140
    • 79551617718 scopus 로고    scopus 로고
    • Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition
    • S. Shankar, D. Nall, S.N. Tang, D. Meeker, J. Passarini, and J. Sharma Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition PLoS One 6 1 2011 e16530
    • (2011) PLoS One , vol.6 , Issue.1 , pp. 16530
    • Shankar, S.1    Nall, D.2    Tang, S.N.3    Meeker, D.4    Passarini, J.5    Sharma, J.6
  • 141
    • 79951901778 scopus 로고    scopus 로고
    • Targeting cell signaling and apoptotic pathways by dietary agents: Role in the prevention and treatment of cancer
    • M.K. Shanmugam, R. Kannaiyan, and G. Sethi Targeting cell signaling and apoptotic pathways by dietary agents: role in the prevention and treatment of cancer Nutr Cancer 63 2 2011 161 173
    • (2011) Nutr Cancer , vol.63 , Issue.2 , pp. 161-173
    • Shanmugam, M.K.1    Kannaiyan, R.2    Sethi, G.3
  • 142
    • 0036735345 scopus 로고    scopus 로고
    • A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer
    • H. Shen, and L. Wang A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer Cancer Res 62 17 2002 4992 4995
    • (2002) Cancer Res , vol.62 , Issue.17 , pp. 4992-4995
    • Shen, H.1    Wang, L.2
  • 143
    • 33644645034 scopus 로고    scopus 로고
    • Beneficial effects of tea and its polyphenols against prostate cancer
    • I.A. Siddiqui, V.M. Adhami, M. Saleem, and H. Mukhtar Beneficial effects of tea and its polyphenols against prostate cancer Mol Nutr Food Res 50 2 2006 130 143
    • (2006) Mol Nutr Food Res , vol.50 , Issue.2 , pp. 130-143
    • Siddiqui, I.A.1    Adhami, V.M.2    Saleem, M.3    Mukhtar, H.4
  • 144
    • 80555123045 scopus 로고    scopus 로고
    • Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications
    • B.N. Singh, S. Shankar, and R.K. Srivastava Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications Biochem Pharmacol 82 12 2011 1807 1821
    • (2011) Biochem Pharmacol , vol.82 , Issue.12 , pp. 1807-1821
    • Singh, B.N.1    Shankar, S.2    Srivastava, R.K.3
  • 145
    • 77949658533 scopus 로고    scopus 로고
    • FOXO transcription factors and VEGF neutralizing antibody enhance antiangiogenic effects of resveratrol
    • R.K. Srivastava, T.G. Unterman, and S. Shankar FOXO transcription factors and VEGF neutralizing antibody enhance antiangiogenic effects of resveratrol Mol Cell Biochem 337 1-2 2010 201 212
    • (2010) Mol Cell Biochem , vol.337 , Issue.12 , pp. 201-212
    • Srivastava, R.K.1    Unterman, T.G.2    Shankar, S.3
  • 146
    • 77953539793 scopus 로고    scopus 로고
    • Hypomethylation and induction of retinoic acid receptor beta 2 by concurrent action of adenosine analogues and natural compounds in breast cancer cells
    • B. Stefanska, K. Rudnicka, A. Bednarek, and K. Fabianowska-Majewska Hypomethylation and induction of retinoic acid receptor beta 2 by concurrent action of adenosine analogues and natural compounds in breast cancer cells Eur J Pharmacol 638 1-3 2010 47 53
    • (2010) Eur J Pharmacol , vol.638 , Issue.13 , pp. 47-53
    • Stefanska, B.1    Rudnicka, K.2    Bednarek, A.3    Fabianowska-Majewska, K.4
  • 147
    • 84865436447 scopus 로고    scopus 로고
    • Epigenetic mechanisms in anti-cancer actions of bioactive food components-the implications in cancer prevention
    • B. Stefanska, H. Karlic, F. Varga, K. Fabianowska-Majewska, and A.G Haslberger Epigenetic mechanisms in anti-cancer actions of bioactive food components-the implications in cancer prevention Br J Pharmacol 167 2 2012 279 297
    • (2012) Br J Pharmacol , vol.167 , Issue.2 , pp. 279-297
    • Stefanska, B.1    Karlic, H.2    Varga, F.3    Fabianowska-Majewska, K.4    Haslberger, A.G.5
  • 148
    • 1342344009 scopus 로고    scopus 로고
    • Modifiable risk factors for cancer
    • C.J. Stein, and G.A. Colditz Modifiable risk factors for cancer Br J Cancer 90 2 2004 299 303
    • (2004) Br J Cancer , vol.90 , Issue.2 , pp. 299-303
    • Stein, C.J.1    Colditz, G.A.2
  • 149
    • 79959484677 scopus 로고    scopus 로고
    • Signals and combinatorial functions of histone modifications
    • T. Suganuma, and J.L. Workman Signals and combinatorial functions of histone modifications Annu Rev Biochem 80 2011 473 499
    • (2011) Annu Rev Biochem , vol.80 , pp. 473-499
    • Suganuma, T.1    Workman, J.L.2
  • 150
    • 33846616766 scopus 로고    scopus 로고
    • Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers
    • A. Sun, and O. Tawfik Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers Prostate 67 2 2007 203 213
    • (2007) Prostate , vol.67 , Issue.2 , pp. 203-213
    • Sun, A.1    Tawfik, O.2
  • 151
    • 41649090153 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells
    • M. Sun, Z. Estrov, Y. Ji, and K.R. Coombes Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells Mol Cancer Ther 7 3 2008 464 473
    • (2008) Mol Cancer Ther , vol.7 , Issue.3 , pp. 464-473
    • Sun, M.1    Estrov, Z.2    Ji, Y.3    Coombes, K.R.4
  • 152
    • 70349316774 scopus 로고    scopus 로고
    • Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression
    • Q. Sun, R. Cong, H. Yan, and H. Gu Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression Oncol Rep 22 3 2009 563 567
    • (2009) Oncol Rep , vol.22 , Issue.3 , pp. 563-567
    • Sun, Q.1    Cong, R.2    Yan, H.3    Gu, H.4
  • 153
    • 54949113264 scopus 로고    scopus 로고
    • Quercetin is able to demethylate the p16INK4a gene promoter
    • S. Tan, and C. Wang Quercetin is able to demethylate the p16INK4a gene promoter Chemotherapy 55 1 2008 6 10
    • (2008) Chemotherapy , vol.55 , Issue.1 , pp. 6-10
    • Tan, S.1    Wang, C.2
  • 154
    • 77449136874 scopus 로고    scopus 로고
    • The TET family of proteins: Functions and roles in disease
    • A.Y. Tan, and J.L. Manley The TET family of proteins: Functions and roles in disease J Mol Cell Biol 1 2 2009 82 92
    • (2009) J Mol Cell Biol , vol.1 , Issue.2 , pp. 82-92
    • Tan, A.Y.1    Manley, J.L.2
  • 155
    • 77955641868 scopus 로고    scopus 로고
    • The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition
    • S.N. Tang, C. Singh, D. Nall, D. Meeker, S. Shankar, and R.K. Srivastava The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition J Mol Signal 5 2010 14
    • (2010) J Mol Signal , vol.5 , pp. 14
    • Tang, S.N.1    Singh, C.2    Nall, D.3    Meeker, D.4    Shankar, S.5    Srivastava, R.K.6
  • 156
    • 84856879533 scopus 로고    scopus 로고
    • EGCG enhances the therapeutic potential of gemcitabine and CP690550 by inhibiting STAT3 signaling pathway in human pancreatic cancer
    • S.N. Tang, J. Fu, S. Shankar, and R.K. Srivastava EGCG enhances the therapeutic potential of gemcitabine and CP690550 by inhibiting STAT3 signaling pathway in human pancreatic cancer PLoS One 7 2 2012 e31067
    • (2012) PLoS One , vol.7 , Issue.2 , pp. 31067
    • Tang, S.N.1    Fu, J.2    Shankar, S.3    Srivastava, R.K.4
  • 157
    • 79952025567 scopus 로고    scopus 로고
    • Curcumin-The paradigm of a multi-target natural compound with applications in cancer prevention and treatment
    • M.H. Teiten, S. Eifes, M. Dicato, and Marc Diederich Curcumin-The paradigm of a multi-target natural compound with applications in cancer prevention and treatment Toxins 2 1 2010 128 162
    • (2010) Toxins , vol.2 , Issue.1 , pp. 128-162
    • Teiten, M.H.1    Eifes, S.2    Dicato, M.3    Diederich, M.4
  • 158
    • 77957721534 scopus 로고    scopus 로고
    • Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFβ signaling pathway in SW480 cells
    • E. Tili, J.J. Michaille, H. Alder, and S. Volinia Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFβ signaling pathway in SW480 cells Biochem Pharmacol 80 12 2010 2057 2065
    • (2010) Biochem Pharmacol , vol.80 , Issue.12 , pp. 2057-2065
    • Tili, E.1    Michaille, J.J.2    Alder, H.3    Volinia, S.4
  • 159
    • 23244450241 scopus 로고    scopus 로고
    • Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane
    • M. Traka, A.V. Gasper, J.A. Smith, and C.J. Hawkey Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane J Nutr Biochem 135 8 2005 1865 1872
    • (2005) J Nutr Biochem , vol.135 , Issue.8 , pp. 1865-1872
    • Traka, M.1    Gasper, A.V.2    Smith, J.A.3    Hawkey, C.J.4
  • 160
    • 73949133652 scopus 로고    scopus 로고
    • Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells
    • W.P. Tsang, and T.T. Kwok Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells J Nutr Biochem 21 2 2010 140 146
    • (2010) J Nutr Biochem , vol.21 , Issue.2 , pp. 140-146
    • Tsang, W.P.1    Kwok, T.T.2
  • 161
    • 78650412626 scopus 로고    scopus 로고
    • Epigenetic regulation of signaling pathways in cancer: Role of the histone methyltransferase EZH2
    • D.P. Tsang, and A.S. Cheng Epigenetic regulation of signaling pathways in cancer: Role of the histone methyltransferase EZH2 J Gastroenterol Hepatol 26 1 2011 19 27
    • (2011) J Gastroenterol Hepatol , vol.26 , Issue.1 , pp. 19-27
    • Tsang, D.P.1    Cheng, A.S.2
  • 162
    • 79952124971 scopus 로고    scopus 로고
    • Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotineand estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells
    • S.H. Tu, C.Y. Ku, and C.T. Ho Tea polyphenol (-)-epigallocatechin-3- gallate inhibits nicotineand estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells Mol Nutr Food Res 55 3 2011 455 466
    • (2011) Mol Nutr Food Res , vol.55 , Issue.3 , pp. 455-466
    • Tu, S.H.1    Ku, C.Y.2    Ho, C.T.3
  • 163
    • 79251635938 scopus 로고    scopus 로고
    • Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
    • I. Varela, and P. Tarpey Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma Nature 469 7331 2011 539 542
    • (2011) Nature , vol.469 , Issue.7331 , pp. 539-542
    • Varela, I.1    Tarpey, P.2
  • 164
    • 78650582970 scopus 로고    scopus 로고
    • Histone lysine methylation and demethylation pathways in cancer
    • R.A. Varier, and H.T. Timmers Histone lysine methylation and demethylation pathways in cancer Biochim Biophys Acta 1815 1 2011 75 89
    • (2011) Biochim Biophys Acta , vol.1815 , Issue.1 , pp. 75-89
    • Varier, R.A.1    Timmers, H.T.2
  • 165
    • 70349975929 scopus 로고    scopus 로고
    • Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer
    • S.R. Volate, S.J. Muga, A.Y. Issa, and D. Nitcheva Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer Mol Carcinog 48 10 2009 920 933
    • (2009) Mol Carcinog , vol.48 , Issue.10 , pp. 920-933
    • Volate, S.R.1    Muga, S.J.2    Issa, A.Y.3    Nitcheva, D.4
  • 166
    • 33846217828 scopus 로고    scopus 로고
    • Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer
    • L.G. Wang, A. Beklemisheva, X.M. Liu, and A.C. Ferrari Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer Mol Carcinog 46 1 2007 24 31
    • (2007) Mol Carcinog , vol.46 , Issue.1 , pp. 24-31
    • Wang, L.G.1    Beklemisheva, A.2    Liu, X.M.3    Ferrari, A.C.4
  • 167
    • 53149144656 scopus 로고    scopus 로고
    • Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis
    • R.H. Wang, Y. Zheng, H.S. Kim, and X. Xu Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis Mol Cell 32 1 2008 11 20
    • (2008) Mol Cell , vol.32 , Issue.1 , pp. 11-20
    • Wang, R.H.1    Zheng, Y.2    Kim, H.S.3    Xu, X.4
  • 169
    • 67149144844 scopus 로고    scopus 로고
    • Ellagitannin (BJA3121), an anti-proliferative natural polyphenol compound, can regulate the expression of miRNAs in HepG2 cancer cells
    • X.Y. Wen, S.Y. Wu, Z.Q. Li, and Z.Q. Liu Ellagitannin (BJA3121), an anti-proliferative natural polyphenol compound, can regulate the expression of miRNAs in HepG2 cancer cells Phytother Res 23 6 2009 778 784
    • (2009) Phytother Res , vol.23 , Issue.6 , pp. 778-784
    • Wen, X.Y.1    Wu, S.Y.2    Li, Z.Q.3    Liu, Z.Q.4
  • 170
    • 77956924029 scopus 로고    scopus 로고
    • Novel CHD7 mutations contributing to the mutation spectrum in patients with CHARGE syndrome
    • K. Wessels, and B. Bohnhorst Novel CHD7 mutations contributing to the mutation spectrum in patients with CHARGE syndrome Eur J Med Genet 53 5 2010 280 285
    • (2010) Eur J Med Genet , vol.53 , Issue.5 , pp. 280-285
    • Wessels, K.1    Bohnhorst, B.2
  • 171
    • 0034530273 scopus 로고    scopus 로고
    • Genetic variation in ICF syndrome: Evidence for genetic heterogeneity
    • C. Wijmenga, and R.S. Hansen Genetic variation in ICF syndrome: evidence for genetic heterogeneity Hum Mutat 16 6 2000 509 517
    • (2000) Hum Mutat , vol.16 , Issue.6 , pp. 509-517
    • Wijmenga, C.1    Hansen, R.S.2
  • 172
    • 79959653996 scopus 로고    scopus 로고
    • SWI/SNF nucleosome remodellers and cancer
    • B.G. Wilson, and C.W. Roberts SWI/SNF nucleosome remodellers and cancer Nat Rev Cancer 11 2011 481 492
    • (2011) Nat Rev Cancer , vol.11 , pp. 481-492
    • Wilson, B.G.1    Roberts, C.W.2
  • 173
    • 77956095231 scopus 로고    scopus 로고
    • Active DNA demethylation: Many roads lead to Rome
    • S.C. Wu, and Y. Zhang Active DNA demethylation: Many roads lead to Rome Nat Rev Mol Cell Biol 11 9 2010 607 620
    • (2010) Nat Rev Mol Cell Biol , vol.11 , Issue.9 , pp. 607-620
    • Wu, S.C.1    Zhang, Y.2
  • 174
    • 56049083256 scopus 로고    scopus 로고
    • Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells
    • N. Xiang, R. Zhao, G. Song, and W. Zhong Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells Carcinogenesis 29 11 2008 2175 2181
    • (2008) Carcinogenesis , vol.29 , Issue.11 , pp. 2175-2181
    • Xiang, N.1    Zhao, R.2    Song, G.3    Zhong, W.4
  • 175
    • 33845458726 scopus 로고    scopus 로고
    • Annexin-I as a potential target for green tea extract induced actin remodeling
    • G.S. Xiao, Y.S. Jin, Q.Y. Lu, and Z.F. Zhang Annexin-I as a potential target for green tea extract induced actin remodeling Int J Cancer 120 1 2006 111 120
    • (2006) Int J Cancer , vol.120 , Issue.1 , pp. 111-120
    • Xiao, G.S.1    Jin, Y.S.2    Lu, Q.Y.3    Zhang, Z.F.4
  • 176
    • 33748089664 scopus 로고    scopus 로고
    • Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2
    • C. Xu, and M.T. Huang Inhibition of 7,12-dimethylbenz(a)anthracene- induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2 Cancer Res 66 16 2006 8293 8296
    • (2006) Cancer Res , vol.66 , Issue.16 , pp. 8293-8296
    • Xu, C.1    Huang, M.T.2
  • 177
    • 77954089584 scopus 로고    scopus 로고
    • Array-based genomic resequencing of human leukemia
    • Y. Yamashita, and J. Yuan Array-based genomic resequencing of human leukemia Oncogene 29 25 2010 3723 3731
    • (2010) Oncogene , vol.29 , Issue.25 , pp. 3723-3731
    • Yamashita, Y.1    Yuan, J.2
  • 178
    • 66549103207 scopus 로고    scopus 로고
    • Serum folate and cancer mortality among U.S. adults: Findings from the Third National Health and Nutritional Examination Survey linked mortality file
    • Q. Yang, R.M. Bostick, J.M. Friedman, and W.D. Flanders Serum folate and cancer mortality among U.S. adults: findings from the Third National Health and Nutritional Examination Survey linked mortality file Cancer Epidemiol Biomarkers Prev 18 5 2009 1439 1447
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , Issue.5 , pp. 1439-1447
    • Yang, Q.1    Bostick, R.M.2    Friedman, J.M.3    Flanders, W.D.4
  • 179
    • 79951767903 scopus 로고    scopus 로고
    • Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells
    • J. Yang, Y. Cao, J. Sun, and Y. Zhang Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells Med Oncol 27 4 2010 1114 1118
    • (2010) Med Oncol , vol.27 , Issue.4 , pp. 1114-1118
    • Yang, J.1    Cao, Y.2    Sun, J.3    Zhang, Y.4
  • 180
    • 80052266351 scopus 로고    scopus 로고
    • Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
    • Yaoting Gui, and Guangwu Guo Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder Nat Genet 43 2011 875 878
    • (2011) Nat Genet , vol.43 , pp. 875-878
    • Gui, Y.1    Guo, G.2
  • 181
    • 13444305417 scopus 로고    scopus 로고
    • Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients
    • Y. Yuasa, H. Nagasaki, Y. Akiyama, and H. Sakai Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients Carcinogenesis 26 1 2005 193 200
    • (2005) Carcinogenesis , vol.26 , Issue.1 , pp. 193-200
    • Yuasa, Y.1    Nagasaki, H.2    Akiyama, Y.3    Sakai, H.4
  • 182
    • 77955589719 scopus 로고    scopus 로고
    • Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway
    • J. Zhang, and T. Zhang Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway Biochem Biophys Res Commun 399 1 2010 1 6
    • (2010) Biochem Biophys Res Commun , vol.399 , Issue.1 , pp. 1-6
    • Zhang, J.1    Zhang, T.2
  • 183
    • 72649104264 scopus 로고    scopus 로고
    • Molecular mechanisms by which selenoproteins affect cancer risk and progression
    • P. Zhuo, and A.M. Diamond Molecular mechanisms by which selenoproteins affect cancer risk and progression Biochim Biophys Acta 1790 11 2009 1546 1554
    • (2009) Biochim Biophys Acta , vol.1790 , Issue.11 , pp. 1546-1554
    • Zhuo, P.1    Diamond, A.M.2
  • 184
    • 80055000824 scopus 로고    scopus 로고
    • RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
    • J. Zuber, and J. Shi RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia Nature 478 7370 2011 524 528
    • (2011) Nature , vol.478 , Issue.7370 , pp. 524-528
    • Zuber, J.1    Shi, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.