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Volumn 1, Issue 2, 2009, Pages 82-92

The TET family of proteins: Functions and roles in disease

Author keywords

Arginine methylation; Cancer; EWS; Fusion proteins; Neuronal disease; RNA binding; Splicing; TAF 15; TLS FUS; Transcription; Translocations

Indexed keywords

TRANSCRIPTION FACTOR;

EID: 77449136874     PISSN: 16742788     EISSN: 17594685     Source Type: Journal    
DOI: 10.1093/jmcb/mjp025     Document Type: Review
Times cited : (216)

References (149)
  • 1
    • 14544271439 scopus 로고    scopus 로고
    • RGG-boxes of the EWS oncoprotein repress a range of transcriptional activation domains
    • DOI 10.1093/nar/gki270
    • Alex, D., and Lee, K. A. (2005). RGG-boxes of the EWS oncoprotein repress a range of transcriptional activation domains. Nucleic Acids Res. 33, 1323-1331. (Pubitemid 41439925)
    • (2005) Nucleic Acids Research , vol.33 , Issue.4 , pp. 1323-1331
    • Alex, D.1    Lee, K.A.W.2
  • 2
    • 0032846542 scopus 로고    scopus 로고
    • Fusion genes in solid tumors
    • DOI 10.1006/scbi.1999.0130
    • Aman, P. (1999). Fusion genes in solid tumors. Semin. Cancer Biol. 9, 303-318. (Pubitemid 29429994)
    • (1999) Seminars in Cancer Biology , vol.9 , Issue.4 , pp. 303-318
    • Aman, P.1
  • 3
    • 48249083430 scopus 로고    scopus 로고
    • The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response
    • Andersson, M. K., Stahlberg, A., Arvidsson, Y., Olofsson, A., Semb, H., Stenman, G., Nilsson, O., and Aman, P. (2008). The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response. BMC Cell Biol. 9, 37.
    • (2008) BMC Cell. Biol. , vol.9 , pp. 37
    • Andersson, M.K.1    Stahlberg, A.2    Arvidsson, Y.3    Olofsson, A.4    Semb, H.5    Stenman, G.6    Nilsson, O.7    Aman, P.8
  • 6
    • 0035839938 scopus 로고    scopus 로고
    • Biology of EWS/ETS fusions in Ewing's family tumors
    • DOI 10.1038/sj.onc.1204598
    • Arvand, A., and Denny, C. T. (2001). Biology of EWS/ETS fusions in Ewing's family tumors. Oncogene 20, 5747-5754. (Pubitemid 32928112)
    • (2001) Oncogene , vol.20 , Issue.40 REV. ISS. 4 , pp. 5747-5754
    • Arvand, A.1    Denny, C.T.2
  • 8
    • 0033539906 scopus 로고    scopus 로고
    • Identification of a novel fusion gene involving hTAF(II)68 and CHN from a t(9;17)(q22;q11.2) translocation in an extraskeletal myxoid chondrosarcoma
    • Attwooll, C., Tariq, M., Harris, M., Coyne, J. D., Telford, N., and Varley, J. M. (1999). Identification of a novel fusion gene involving hTAFII68 and CHN from a t (9;17) (q22;q11.2) translocation in an extraskeletal myxoid chondrosarcoma. Oncogene 18, 7599-7601. (Pubitemid 30035062)
    • (1999) Oncogene , vol.18 , Issue.52 , pp. 7599-7601
    • Attwooll, C.1    Tariq, M.2    Harris, M.3    Coyne, J.D.4    Telford, N.5    Varley, J.M.6
  • 9
    • 41549137834 scopus 로고    scopus 로고
    • Ewing sarcoma protein ewsr1 maintains mitotic integrity and proneural cell survival in the zebrafish embryo
    • Azuma, M., Embree, L. J., Sabaawy, H., and Hickstein, D. D. (2007). Ewing sarcoma protein ewsr1 maintains mitotic integrity and proneural cell survival in the zebrafish embryo. PLoS One 2, e979.
    • (2007) PLoS One , vol.2
    • Azuma, M.1    Embree, L.J.2    Sabaawy, H.3    Hickstein, D.D.4
  • 10
    • 62049084331 scopus 로고    scopus 로고
    • O-GlcNAcylation is involved in the transcriptional activity of EWS-FLI1 in Ewing's sarcoma
    • Bachmaier, R., Aryee, D. N., Jug, G., Kauer, M., Kreppel, M., Lee, K. A., and Kovar, H. (2009). O-GlcNAcylation is involved in the transcriptional activity of EWS-FLI1 in Ewing's sarcoma. Oncogene 28, 1280-1284.
    • (2009) Oncogene , vol.28 , pp. 1280-1284
    • Bachmaier, R.1    Aryee, D.N.2    Jug, G.3    Kauer, M.4    Kreppel, M.5    Lee, K.A.6    Kovar, H.7
  • 11
    • 0033607753 scopus 로고    scopus 로고
    • Human 75-kDa DNA-pairing protein is identical to the pro-oncoprotein TLS/FUS and is able to promote D-loop formation
    • Baechtold, H., Kuroda, M., Sok, J., Ron, D., Lopez, B. S., and Akhmedov, A. T. (1999). Human 75-kDa DNA-pairing protein is identical to the pro-oncoprotein TLS/FUS and is able to promote D-loop formation. J. Biol. Chem. 274, 34337-34342. (Pubitemid 129511776)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.48 , pp. 34337-34342
    • Baechtold, H.1    Kuroda, M.2    Sok, J.3    Ron, D.4    Lopez, B.S.5    Akhmedov, A.T.6
  • 12
    • 0028209984 scopus 로고
    • DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma
    • Bailly, R. A., Bosselut, R., Zucman, J., Cormier, F., Delattre, O., Roussel, M., Thomas, G., and Ghysdael, J. (1994). DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t (11;22) translocation in Ewing sarcoma. Mol. Cell. Biol. 14, 3230-3241. (Pubitemid 24132736)
    • (1994) Molecular and Cellular Biology , vol.14 , Issue.5 , pp. 3230-3241
    • Bailly, R.-A.1    Bosselut, R.2    Zucman, J.3    Cormier, F.4    Delattre, O.5    Roussel, M.6    Thomas, G.7    Ghysdael, J.8
  • 14
    • 17444381645 scopus 로고    scopus 로고
    • Delocalization of the multifunctional RNA splicing factor TLS/FUS in hippocampal neurones: Exclusion from the nucleus and accumulation in dendritic granules and spine heads
    • DOI 10.1016/j.neulet.2004.12.071
    • Belly, A., Moreau-Gachelin, F., Sadoul, R., and Goldberg, Y. (2005). Delocalization of the multifunctional RNA splicing factor TLS/FUS in hippocampal neurones: exclusion from the nucleus and accumulation in dendritic granules and spine heads. Neurosci. Lett. 379, 152-157. (Pubitemid 40544525)
    • (2005) Neuroscience Letters , vol.379 , Issue.3 , pp. 152-157
    • Belly, A.1    Moreau-Gachelin, F.2    Sadoul, R.3    Goldberg, Y.4
  • 15
    • 0035378344 scopus 로고    scopus 로고
    • Exposure on cell surface and extensive arginine methylation of Ewing sarcoma (EWS) protein
    • Belyanskaya, L. L., Gehrig, P. M., and Gehring, H. (2001). Exposure on cell surface and extensive arginine methylation of Ewing sarcoma (EWS) protein. J. Biol. Chem. 276, 18681-18687.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18681-18687
    • Belyanskaya, L.L.1    Gehrig, P.M.2    Gehring, H.3
  • 16
    • 0042063647 scopus 로고    scopus 로고
    • Expression and subcellular localization of Ewing sarcoma (EWS) protein is affected by the methylation process
    • DOI 10.1016/S0014-4827(03)00221-0
    • Belyanskaya, L. L., Delattre, O., and Gehring, H. (2003). Expression and subcellular localization of Ewing sarcoma (EWS) protein is affected by the methylation process. Exp. Cell Res. 288, 374-381. (Pubitemid 36959953)
    • (2003) Experimental Cell Research , vol.288 , Issue.2 , pp. 374-381
    • Belyanskaya, L.L.1    Delattre, O.2    Gehring, H.3
  • 17
    • 19344378943 scopus 로고    scopus 로고
    • Rules of engagement: Co-transcriptional recruitment of pre-mRNA processing factors
    • DOI 10.1016/j.ceb.2005.04.006, PII S0955067405000487, Nucleus and Gene Expression
    • Bentley, D. L. (2005). Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors. Curr. Opin. Cell Biol. 17, 251-256. (Pubitemid 40719913)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.3 , pp. 251-256
    • Bentley, D.L.1
  • 19
    • 0029812470 scopus 로고    scopus 로고
    • HTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II
    • Bertolotti, A., Lutz, Y., Heard, D. J., Chambon, P., and Tora, L. (1996). hTAF (II) 68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II. EMBO J. 15, 5022-5031. (Pubitemid 26315812)
    • (1996) EMBO Journal , vol.15 , Issue.18 , pp. 5022-5031
    • Bertolotti, A.1    Lutz, Y.2    Heard, D.J.3    Chambon, P.4    Tora, L.5
  • 20
    • 0031935157 scopus 로고    scopus 로고
    • EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: Interactions between two members of the tet family, EWS and HTAF(II)68, and subunits of TFIID and RNA polymerase II complexes
    • Bertolotti, A., Melot, T., Acker, J., Vigneron, M., Delattre, O., and Tora, L. (1998). EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes. Mol. Cell. Biol. 18, 1489-1497. (Pubitemid 28100914)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.3 , pp. 1489-1497
    • Bertolotti, A.1    Melot, T.2    Acker, J.3    Vigneron, M.4    Delattre, O.5    Tora, L.6
  • 21
    • 0033598946 scopus 로고    scopus 로고
    • The N-terminal domain of human TAF(II)68 displays transactivation and oncogenic properties
    • Bertolotti, A., Bell, B., and Tora, L. (1999). The N-terminal domain of human TAFII68 displays transactivation and oncogenic properties. Oncogene 18, 8000-8010. (Pubitemid 30050561)
    • (1999) Oncogene , vol.18 , Issue.56 , pp. 8000-8010
    • Bertolotti, A.1    Bell, B.2    Tora, L.3
  • 22
    • 0033527059 scopus 로고    scopus 로고
    • Human POMp75 is identified as the pro-oncoprotein TLS/FUS: Both POMp75 and POMp100 DNA homologous pairing activities are associated to cell proliferation
    • DOI 10.1038/sj.onc.1203048
    • Bertrand, P., Akhmedov, A. T., Delacote, F., Durrbach, A., and Lopez, B. S. (1999). Human POMp75 is identified as the pro-oncoprotein TLS/FUS: both POMp75 and POMp100 DNA homologous pairing activities are associated to cell proliferation. Oncogene 18, 4515-4521. (Pubitemid 29396659)
    • (1999) Oncogene , vol.18 , Issue.31 , pp. 4515-4521
    • Bertrand, P.1    Akhmedov, A.T.2    Delacote, F.3    Durrbach, A.4    Lopez, B.S.5
  • 23
    • 0017744030 scopus 로고
    • Identification and characterization of the packaging proteins of core 40S hnRNP particles
    • Beyer, A. L., Christensen, M. E., Walker, B. W., and LeStourgeon, W. M. (1977). Identification and characterization of the packaging proteins of core 40S hnRNP particles. Cell 11, 127-138. (Pubitemid 8126060)
    • (1977) Cell , vol.11 , Issue.1 , pp. 127-138
    • Beyer, A.L.1    Christensen, M.E.2    Walker, B.W.3    LeStourgeon, W.M.4
  • 24
    • 0027404264 scopus 로고
    • Distinct TFIID complexes mediate the effect of different transcriptional activators
    • Brou, C., Chaudhary, S., Davidson, I., Lutz, Y., Wu, J., Egly, J. M., Tora, L., and Chambon, P. (1993). Distinct TFIID complexes mediate the effect of different transcriptional activators. EMBO J. 12, 489-499. (Pubitemid 23073695)
    • (1993) EMBO Journal , vol.12 , Issue.2 , pp. 489-499
    • Brou, C.1    Chaudhary, S.2    Davidson, I.3    Lutz, Y.4    Wu, J.5    Egly, J.-M.6    Tora, L.7    Chambon, P.8
  • 25
    • 0028129989 scopus 로고
    • Conserved structures and diversity of functions of RNA-binding proteins
    • Burd, C. G., and Dreyfuss, G. (1994). Conserved structures and diversity of functions of RNA-binding proteins. Science 265, 615-621. (Pubitemid 24268271)
    • (1994) Science , vol.265 , Issue.5172 , pp. 615-621
    • Burd, C.G.1    Dreyfuss, G.2
  • 26
    • 0029372980 scopus 로고
    • Identification of hnRNP P2 as TLS/FUS using electrospray mass spectrometry
    • Calvio, C., Neubauer, G., Mann, M., and Lamond, A. I. (1995). Identification of hnRNP P2 as TLS/FUS using electrospray mass spectrometry. RNA 1, 724-733.
    • (1995) RNA , vol.1 , pp. 724-733
    • Calvio, C.1    Neubauer, G.2    Mann, M.3    Lamond, A.I.4
  • 27
    • 0035328667 scopus 로고    scopus 로고
    • Oncogenic TLS/ERG and EWS/Fli-1 fusion proteins inhibit RNA splicing mediated by YB-1 protein
    • Chansky, H. A., Hu, M., Hickstein, D. D., and Yang, L. (2001). Oncogenic TLS/ERG and EWS/Fli-1 fusion proteins inhibit RNA splicing mediated by YB-1 protein. Cancer Res. 61, 3586-3590. (Pubitemid 32694966)
    • (2001) Cancer Research , vol.61 , Issue.9 , pp. 3586-3590
    • Chansky, H.A.1    Hu, M.2    Hickstein, D.D.3    Yang, L.4
  • 29
    • 0027227651 scopus 로고
    • Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma
    • DOI 10.1038/363640a0
    • Crozat, A., Aman, P., Mandahl, N., and Ron, D. (1993). Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma. Nature 363, 640-644. (Pubitemid 23227627)
    • (1993) Nature , vol.363 , Issue.6430 , pp. 640-644
    • Crozat, A.1    Aman, P.2    Mandahl, N.3    Ron, D.4
  • 31
    • 44449142796 scopus 로고    scopus 로고
    • The CTD role in cotranscriptional RNA processing and surveillance
    • de Almeida, S. F., and Carmo-Fonseca, M. (2008). The CTD role in cotranscriptional RNA processing and surveillance. FEBS Lett. 582, 1971-1976.
    • (2008) FEBS Lett. , vol.582 , pp. 1971-1976
    • De Almeida, S.F.1    Carmo-Fonseca, M.2
  • 33
    • 0030774839 scopus 로고    scopus 로고
    • The prooncoprotein EWS binds calmodulin and is phosphorylated by protein kinase C through an IQ domain
    • DOI 10.1074/jbc.272.43.27369
    • Deloulme, J. C., Prichard, L., Delattre, O., and Storm, D. R. (1997). The prooncoprotein EWS binds calmodulin and is phosphorylated by protein kinase C through an IQ domain. J. Biol. Chem. 272, 27369-27377. (Pubitemid 27452704)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.43 , pp. 27369-27377
    • Deloulme, J.C.1    Prichard, L.2    Delattre, O.3    Storm, D.R.4
  • 34
    • 0033134777 scopus 로고    scopus 로고
    • Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA
    • Ding, J., Hayashi, M. K., Zhang, Y., Manche, L., Krainer, A. R., and Xu, R. M. (1999). Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA. Genes Dev. 13, 1102-1115. (Pubitemid 29233142)
    • (1999) Genes and Development , vol.13 , Issue.9 , pp. 1102-1115
    • Ding, J.1    Hayashi, M.K.2    Zhang, Y.3    Manche, L.4    Krainer, A.R.5    Xu, R.-M.6
  • 35
    • 0037218795 scopus 로고    scopus 로고
    • Alteration of mesodermal cell differentiation by EWS/FLI-1, the oncogene implicated in Ewing's sarcoma
    • DOI 10.1128/MCB.23.2.482-492.2003
    • Eliazer, S., Spencer, J., Ye, D., Olson, E., and Ilaria, R. L., Jr. (2003). Alteration of mesodermal cell differentiation by EWS/FLI-1, the oncogene implicated in Ewing's sarcoma. Mol. Cell. Biol. 23, 482-492. (Pubitemid 36050543)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.2 , pp. 482-492
    • Eliazer, S.1    Spencer, J.2    Ye, D.3    Olson, E.4    Ilaria Jr., R.L.5
  • 36
    • 0035924345 scopus 로고    scopus 로고
    • Stimulatory effect of splicing factors on transcriptional elongation
    • DOI 10.1038/414929a
    • Fong, Y. W., and Zhou, Q. (2001). Stimulatory effect of splicing factors on transcriptional elongation. Nature 414, 929-933. (Pubitemid 34024746)
    • (2001) Nature , vol.414 , Issue.6866 , pp. 929-933
    • Fong, Y.W.1    Zhou, Q.2
  • 37
    • 30544448358 scopus 로고    scopus 로고
    • TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines
    • DOI 10.1242/jcs.02692
    • Fujii, R., and Takumi, T. (2005). TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines. J. Cell Sci. 118, 5755-5765. (Pubitemid 43079269)
    • (2005) Journal of Cell Science , vol.118 , Issue.24 , pp. 5755-5765
    • Fujii, R.1    Takumi, T.2
  • 38
    • 15744378126 scopus 로고    scopus 로고
    • The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology
    • DOI 10.1016/j.cub.2005.01.058
    • Fujii, R., Okabe, S., Urushido, T., Inoue, K., Yoshimura, A., Tachibana, T., Nishikawa, T., Hicks, G. G., and Takumi, T. (2005). The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology. Curr. Biol. 15, 587-593. (Pubitemid 40413401)
    • (2005) Current Biology , vol.15 , Issue.6 , pp. 587-593
    • Fujii, R.1    Okabe, S.2    Urushido, T.3    Inoue, K.4    Yoshimura, A.5    Tachibana, T.6    Nishikawa, T.7    Hicks, G.G.8    Takumi, T.9
  • 39
    • 0035845854 scopus 로고    scopus 로고
    • EWS-ATF-1 chimeric protein in soft tissue clear cell sarcoma associates with CREB-binding protein and interferes with p53-mediated trans-activation function
    • DOI 10.1038/sj.onc.1204684
    • Fujimura, Y., Siddique, H., Lee, L., Rao, V. N., and Reddy, E. S. (2001). EWS-ATF-1 chimeric protein in soft tissue clear cell sarcoma associates with CREB-binding protein and interferes with p53-mediated trans-activation function. Oncogene 20, 6653-6659. (Pubitemid 33020594)
    • (2001) Oncogene , vol.20 , Issue.46 , pp. 6653-6659
    • Fujimura, Y.1    Siddique, H.2    Lee, L.3    Rao, V.N.4    Reddy, E.S.P.5
  • 40
    • 53649107137 scopus 로고    scopus 로고
    • DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing's tumor cells
    • Garcia-Aragoncillo, E., Carrillo, J., Lalli, E., Agra, N., Gomez-Lopez, G., Pestana, A., and Alonso, J. (2008). DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing's tumor cells. Oncogene 27, 6034-6043.
    • (2008) Oncogene , vol.27 , pp. 6034-6043
    • Garcia-Aragoncillo, E.1    Carrillo, J.2    Lalli, E.3    Agra, N.4    Gomez-Lopez, G.5    Pestana, A.6    Alonso, J.7
  • 41
    • 54049138797 scopus 로고    scopus 로고
    • Identification and characterization of FUS/TLS as a new target of ATM
    • Gardiner, M., Toth, R., Vandermoere, F., Morrice, N. A., and Rouse, J. (2008). Identification and characterization of FUS/TLS as a new target of ATM. Biochem. J. 415, 297-307.
    • (2008) Biochem. J. , vol.415 , pp. 297-307
    • Gardiner, M.1    Toth, R.2    Vandermoere, F.3    Morrice, N.A.4    Rouse, J.5
  • 42
    • 17044427464 scopus 로고    scopus 로고
    • The EWS-WT1 gene fusion in desmoplastic small round cell tumor
    • Gerald, W. L., and Haber, D. A. (2005). The EWS-WT1 gene fusion in desmoplastic small round cell tumor. Semin. Cancer Biol. 15, 197-205.
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 197-205
    • Gerald, W.L.1    Haber, D.A.2
  • 43
    • 34548052223 scopus 로고    scopus 로고
    • EWS/FLI-1 oncoprotein subtypes impose different requirements for transformation and metastatic activity in a murine model
    • DOI 10.1007/s00109-007-0202-5
    • Gonzalez, I., Vicent, S., de Alava, E., and Lecanda, F. (2007). EWS/FLI-1 oncoprotein subtypes impose different requirements for transformation and metastatic activity in a murine model. J. Mol. Med. 85, 1015-1029. (Pubitemid 47282792)
    • (2007) Journal of Molecular Medicine , vol.85 , Issue.9 , pp. 1015-1029
    • Gonzalez, I.1    Vicent, S.2    De Alava, E.3    Lecanda, F.4
  • 45
    • 33845188648 scopus 로고    scopus 로고
    • An in vitro enzymatic assay coupled to proteomics analysis reveals a new DNA processing activity for Ewing sarcoma and TAF(II)68 proteins
    • DOI 10.1002/pmic.200600259
    • Guipaud, O., Guillonneau, F., Labas, V., Praseuth, D., Rossier, J., Lopez, B., and Bertrand, P. (2006). An in vitro enzymatic assay coupled to proteomics analysis reveals a new DNA processing activity for Ewing sarcoma and TAF (II) 68 proteins. Proteomics 6, 5962-5972. (Pubitemid 44851382)
    • (2006) Proteomics , vol.6 , Issue.22 , pp. 5962-5972
    • Guipaud, O.1    Guillonneau, F.2    Labas, V.3    Praseuth, D.4    Rossier, J.5    Lopez, B.6    Bertrand, P.7
  • 46
    • 0032848660 scopus 로고    scopus 로고
    • Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein
    • DOI 10.1038/13854
    • Hahm, K. B., Cho, K., Lee, C., Im, Y. H., Chang, J., Choi, S. G., Sorensen, P. H., Thiele, C. J., and Kim, S. J. (1999). Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein. Nat. Genet. 23, 222-227. (Pubitemid 29455398)
    • (1999) Nature Genetics , vol.23 , Issue.2 , pp. 222-227
    • Hahm, K.-B.1    Cho, K.2    Lee, C.3    Im, Y.-H.4    Chang, J.5    Choi, S.-G.6    Sorensen, P.H.B.7    Thiele, C.J.8    Kim, S.-J.9
  • 47
    • 0032570707 scopus 로고    scopus 로고
    • The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS
    • DOI 10.1074/jbc.273.9.4838
    • Hallier, M., Lerga, A., Barnache, S., Tavitian, A., and Moreau-Gachelin, F. (1998). The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS. J. Biol. Chem. 273, 4838-4842. (Pubitemid 28108632)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.9 , pp. 4838-4842
    • Hallier, M.1    Lerga, A.2    Barnache, S.3    Tavitian, A.4    Moreau-Gachelin, F.5
  • 49
    • 0034659241 scopus 로고    scopus 로고
    • RNA polymerase II and the integration of nuclear events
    • Hirose, Y., and Manley, J. L. (2000). RNA polymerase II and the integration of nuclear events. Genes Dev. 14, 1415-1429. (Pubitemid 30421835)
    • (2000) Genes and Development , vol.14 , Issue.12 , pp. 1415-1429
    • Hirose, Y.1    Manley, J.L.2
  • 50
    • 0034706912 scopus 로고    scopus 로고
    • Translin binds to the sequences adjacent to the breakpoints of the TLS and CHOP genes in liposarcomas with translocation t (12;6)
    • Hosaka, T., Kanoe, H., Nakayama, T., Murakami, H., Yamamoto, H., Nakamata, T., Tsuboyama, T., Oka, M., Kasai, M., Sasaki, M. S., et al. (2000). Translin binds to the sequences adjacent to the breakpoints of the TLS and CHOP genes in liposarcomas with translocation t (12;6). Oncogene 19, 5821-5825.
    • (2000) Oncogene , vol.19 , pp. 5821-5825
    • Hosaka, T.1    Kanoe, H.2    Nakayama, T.3    Murakami, H.4    Yamamoto, H.5    Nakamata, T.6    Tsuboyama, T.7    Oka, M.8    Kasai, M.9    Sasaki, M.S.10
  • 53
    • 0029053747 scopus 로고
    • Association of SARFH (sarcoma-associated RNA-binding fly homolog) with regions of chromatin transcribed by RNA polymerase II
    • Immanuel, D., Zinszner, H., and Ron, D. (1995). Association of SARFH (sarcoma-associated RNA-binding fly homolog) with regions of chromatin transcribed by RNA polymerase II. Mol. Cell. Biol. 15, 4562-4571.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4562-4571
    • Immanuel, D.1    Zinszner, H.2    Ron, D.3
  • 54
    • 0033619101 scopus 로고    scopus 로고
    • Transforming activity of EWS/FLI is not strictly dependent upon DNA-binding activity
    • DOI 10.1038/sj.onc.1202940
    • Jaishankar, S., Zhang, J., Roussel, M. F., and Baker, S. J. (1999). Transforming activity of EWS/FLI is not strictly dependent upon DNA-binding activity. Oncogene 18, 5592-5597. (Pubitemid 29481506)
    • (1999) Oncogene , vol.18 , Issue.40 , pp. 5592-5597
    • Jaishankar, S.1    Zhang, J.2    Roussel, M.F.3    Baker, S.J.4
  • 55
    • 28044468016 scopus 로고    scopus 로고
    • EWS-ETS oncoproteins: The linchpins of Ewing tumors
    • DOI 10.1016/j.gene.2005.08.007, PII S0378111905005056
    • Janknecht, R. (2005). EWS-ETS oncoproteins: the linchpins of Ewing tumors. Gene 363, 1-14. (Pubitemid 41691887)
    • (2005) Gene , vol.363 , Issue.1-2 , pp. 1-14
    • Janknecht, R.1
  • 56
    • 63049100536 scopus 로고    scopus 로고
    • PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function
    • Jobert, L., Argentini, M., and Tora, L. (2009a). PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function. Exp. Cell Res. 315, 1273-1286.
    • (2009) Exp. Cell. Res. , vol.315 , pp. 1273-1286
    • Jobert, L.1    Argentini, M.2    Tora, L.3
  • 58
    • 2442435550 scopus 로고    scopus 로고
    • nrb associates with the 50 splice site within large transcription/splicing complexes
    • DOI 10.1038/sj.emboj.7600187
    • Kameoka, S., Duque, P., and Konarska, M. M. (2004). p54 (nrb) associates with the 50 splice site within large transcription/splicing complexes. EMBO J. 23, 1782-1791. (Pubitemid 38649641)
    • (2004) EMBO Journal , vol.23 , Issue.8 , pp. 1782-1791
    • Kameoka, S.1    Duque, P.2    Konarska, M.M.3
  • 59
    • 4143088149 scopus 로고    scopus 로고
    • Kinesin transports RNA: Isolation and characterization of an RNA-transporting granule
    • DOI 10.1016/j.neuron.2004.07.022, PII S0896627304004635
    • Kanai, Y., Dohmae, N., and Hirokawa, N. (2004). Kinesin transports RNA: isolation and characterization of an RNA-transporting granule. Neuron 43, 513-525. (Pubitemid 39094678)
    • (2004) Neuron , vol.43 , Issue.4 , pp. 513-525
    • Kanai, Y.1    Dohmae, N.2    Hirokawa, N.3
  • 60
    • 0033590650 scopus 로고    scopus 로고
    • Characteristics of genomic breakpoints in TLS-CHOP translocations in liposarcomas suggest the involvement of Translin and topoisomerase II in the process of translocation
    • DOI 10.1038/sj.onc.1202364
    • Kanoe, H., Nakayama, T., Hosaka, T., Murakami, H., Yamamoto, H., Nakashima, Y., Tsuboyama, T., Nakamura, T., Ron, D., Sasaki, M. S., et al. (1999). Characteristics of genomic breakpoints in TLS-CHOP translocations in liposarcomas suggest the involvement of Translin and topoisomerase II in the process of translocation. Oncogene 18, 721-729. (Pubitemid 29080329)
    • (1999) Oncogene , vol.18 , Issue.3 , pp. 721-729
    • Kanoe, H.1    Nakayama, T.2    Hosaka, T.3    Murakami, H.4    Yamamoto, H.5    Nakashima, Y.6    Tsuboyama, T.7    Nakamura, T.8    Ron, D.9    Sasaki, M.S.10    Toguchida, J.11
  • 62
    • 62149139782 scopus 로고    scopus 로고
    • Phosphorylation of EWS and EWS-Fli1 in response to DNA damage
    • Klevernic, I. V., Morton, S., Davis, R. J., and Cohen, P. (2008). Phosphorylation of EWS and EWS-Fli1 in response to DNA damage. Biochem. J. 418, 625-634.
    • (2008) Biochem. J. , vol.418 , pp. 625-634
    • Klevernic, I.V.1    Morton, S.2    Davis, R.J.3    Cohen, P.4
  • 63
    • 0347985744 scopus 로고    scopus 로고
    • Translocated in liposarcoma (TLS) is a substrate for fibroblast growth factor receptor-1
    • DOI 10.1016/j.cellsig.2003.09.007
    • Klint, P., Hellman, U., Wernstedt, C., Aman, P., Ron, D., and Claesson-Welsh, L. (2004). Translocated in liposarcoma (TLS) is a substrate for fibroblast growth factor receptor-1. Cell Signal. 16, 515-520. (Pubitemid 38058634)
    • (2004) Cellular Signalling , vol.16 , Issue.4 , pp. 515-520
    • Klint, P.1    Hellman, U.2    Wernstedt, C.3    Aman, P.4    Ron, D.5    Claesson-Welsh, L.6
  • 64
    • 4644334742 scopus 로고    scopus 로고
    • Multiple links between transcription and splicing
    • DOI 10.1261/rna.7100104
    • Kornblihtt, A. R., de la Mata, M., Fededa, J. P., Munoz, M. J., and Nogues, G. (2004). Multiple links between transcription and splicing. RNA 10, 1489-1498. (Pubitemid 39288183)
    • (2004) RNA , vol.10 , Issue.10 , pp. 1489-1498
    • Kornblihtt, A.R.1    De La Mata, M.2    Fededa, J.P.3    Munoz, M.J.4    Nogues, G.5
  • 65
    • 17044415589 scopus 로고    scopus 로고
    • Context matters: The hen or egg problem in Ewing's sarcoma
    • Kovar, H. (2005). Context matters: the hen or egg problem in Ewing's sarcoma. Semin. Cancer Biol. 15, 189-196.
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 189-196
    • Kovar, H.1
  • 69
    • 0036866596 scopus 로고    scopus 로고
    • Multifunctional zinc finger proteins in development and disease
    • Ladomery, M., and Dellaire, G. (2002). Multifunctional zinc finger proteins in development and disease. Ann. Hum. Genet. 66, 331-342. (Pubitemid 36004223)
    • (2002) Annals of Human Genetics , vol.66 , Issue.5-6 , pp. 331-342
    • Ladomery, M.1    Dellaire, G.2
  • 70
    • 34247347737 scopus 로고    scopus 로고
    • Ewings family oncoproteins: Drunk, disorderly and in search of partners
    • DOI 10.1038/cr.2007.22, PII CR200722
    • Lee, K. A. (2007). Ewings family oncoproteins: drunk, disorderly and in search of partners. Cell Res. 17, 286-288. (Pubitemid 46639926)
    • (2007) Cell Research , vol.17 , Issue.4 , pp. 286-288
    • Lee, K.A.W.1
  • 71
    • 1842839807 scopus 로고    scopus 로고
    • II68 (NTD)-mediated transactivation by v-Src
    • DOI 10.1016/S0014-5793(04)00314-X, PII S001457930400314X
    • Lee, H. J., Kim, S., Pelletier, J., and Kim, J. (2004). Stimulation of hTAFII68 (NTD)-mediated transactivation by v-Src. FEBS Lett. 564, 188-198. (Pubitemid 38490723)
    • (2004) FEBS Letters , vol.564 , Issue.1-2 , pp. 188-198
    • Lee, H.J.1    Kim, S.2    Pelletier, J.3    Kim, J.4
  • 72
    • 20344371441 scopus 로고    scopus 로고
    • Stimulation of Oct-4 activity by Ewing's sarcoma protein
    • DOI 10.1634/stemcells.2004-0375
    • Lee, J., Rhee, B. K., Bae, G. Y., Han, Y. M., and Kim, J. (2005). Stimulation of Oct-4 activity by Ewing's sarcoma protein. Stem Cells 23, 738-751. (Pubitemid 40791789)
    • (2005) Stem Cells , vol.23 , Issue.6 , pp. 738-751
    • Lee, J.1    Rhee, B.K.2    Bae, G.-Y.3    Han, Y.-M.4    Kim, J.5
  • 74
    • 0036560740 scopus 로고    scopus 로고
    • The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts
    • DOI 10.1016/S1535-6108(02)00056-9
    • Lessnick, S. L., Dacwag, C. S., and Golub, T. R. (2002). The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts. Cancer Cell 1, 393-401. (Pubitemid 41039140)
    • (2002) Cancer Cell , vol.1 , Issue.4 , pp. 393-401
    • Lessnick, S.L.1    Dacwag, C.S.2    Golub, T.R.3
  • 75
    • 0034725703 scopus 로고    scopus 로고
    • Transcriptional activation by the Ewing's sarcoma (EWS) oncogene can be cis-repressed by the EWS RNA-binding domain
    • DOI 10.1074/jbc.M002961200
    • Li, K. K., and Lee, K. A. (2000). Transcriptional activation by the Ewing's sarcoma (EWS) oncogene can be cis-repressed by the EWS RNA-binding domain. J. Biol. Chem. 275, 23053-23058. (Pubitemid 30646195)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.30 , pp. 23053-23058
    • Li, K.K.C.1    Lee, K.A.W.2
  • 76
    • 0032190621 scopus 로고    scopus 로고
    • The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor
    • Li, X. Y., and Green, M. R. (1998). The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor. Genes Dev. 12, 2992-2996. (Pubitemid 28469301)
    • (1998) Genes and Development , vol.12 , Issue.19 , pp. 2992-2996
    • Li, X.-Y.1    Green, M.R.2
  • 78
    • 0033119006 scopus 로고    scopus 로고
    • Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma
    • Lin, P. P., Brody, R. I., Hamelin, A. C., Bradner, J. E., Healey, J. H., and Ladanyi, M. (1999). Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma. Cancer Res. 59, 1428-1432. (Pubitemid 29160104)
    • (1999) Cancer Research , vol.59 , Issue.7 , pp. 1428-1432
    • Lin, P.P.1    Brody, R.I.2    Hamelin, A.C.3    Bradner, J.E.4    Healey, J.H.5    Ladanyi, M.6
  • 79
    • 0028957320 scopus 로고
    • In vivo and in vitro arginine methylation of RNA-binding proteins
    • Liu, Q., and Dreyfuss, G. (1995). In vivo and in vitro arginine methylation of RNA-binding proteins. Mol. Cell. Biol. 15, 2800-2808.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2800-2808
    • Liu, Q.1    Dreyfuss, G.2
  • 80
    • 0036829064 scopus 로고    scopus 로고
    • Nuclear coupling: RNA processing reaches back to transcription
    • DOI 10.1038/nsb1102-790
    • Manley, J. L. (2002). Nuclear coupling: RNA processing reaches back to transcription. Nat. Struct. Biol. 9, 790-791. (Pubitemid 35257773)
    • (2002) Nature Structural Biology , vol.9 , Issue.11 , pp. 790-791
    • Manley, J.L.1
  • 81
    • 0036791118 scopus 로고    scopus 로고
    • Recurrent rearrangement of the Ewing's sarcoma gene, EWSR1, or its homologue, TAF15, with the transcription factor CIZ/NMP4 in acute leukemia
    • Martini, A., La Starza, R., Janssen, H., Bilhou-Nabera, C., Corveleyn, A., Somers, R., Aventin, A., Foa, R., Hagemeijer, A., Mecucci, C., et al. (2002). Recurrent rearrangement of the Ewing's sarcoma gene, EWSR1, or its homologue, TAF15, with the transcription factor CIZ/NMP4 in acute leukemia. Cancer Res. 62, 5408-5412.
    • (2002) Cancer Res. , vol.62 , pp. 5408-5412
    • Martini, A.1    La Starza, R.2    Janssen, H.3    Bilhou-Nabera, C.4    Corveleyn, A.5    Somers, R.6    Aventin, A.7    Foa, R.8    Hagemeijer, A.9    Mecucci, C.10
  • 82
    • 0030707948 scopus 로고    scopus 로고
    • EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic
    • May, W. A., Arvand, A., Thompson, A. D., Braun, B. S., Wright, M., and Denny, C. T. (1997). EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic. Nat. Genet. 17, 495-497. (Pubitemid 27518406)
    • (1997) Nature Genetics , vol.17 , Issue.4 , pp. 495-497
    • May, W.A.1    Arvand, A.2    Thompson, A.D.3    Braun, B.S.4    Wright, M.5    Denny, C.T.6
  • 83
    • 0344407006 scopus 로고    scopus 로고
    • Proto-oncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteins
    • DOI 10.1016/S0014-4827(02)00046-0
    • Meissner, M., Lopato, S., Gotzmann, J., Sauermann, G., and Barta, A. (2003). Proto-oncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteins. Exp. Cell Res. 283, 184-195. (Pubitemid 36269024)
    • (2003) Experimental Cell Research , vol.283 , Issue.2 , pp. 184-195
    • Meissner, M.1    Lopato, S.2    Gotzmann, J.3    Sauermann, G.4    Barta, A.5
  • 84
    • 0034823778 scopus 로고    scopus 로고
    • Characterization of a new brain-specific isoform of the EWS oncoprotein
    • DOI 10.1046/j.1432-1327.2001.02251.x
    • Melot, T., Dauphinot, L., Sevenet, N., Radvanyi, F., and Delattre, O. (2001). Characterization of a new brain-specific isoform of the EWS oncoprotein. Eur. J. Biochem. 268, 3483-3489. (Pubitemid 32862941)
    • (2001) European Journal of Biochemistry , vol.268 , Issue.12 , pp. 3483-3489
    • Melot, T.1    Dauphinot, L.2    Sevenet, N.3    Radvanyi, F.4    Delattre, O.5
  • 86
    • 0030588652 scopus 로고    scopus 로고
    • Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins
    • DOI 10.1006/geno.1996.0591
    • Morohoshi, F., Arai, K., Takahashi, E. I., Tanigami, A., and Ohki, M. (1996). Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins. Genomics 38, 51-57. (Pubitemid 26423913)
    • (1996) Genomics , vol.38 , Issue.1 , pp. 51-57
    • Morohoshi, F.1    Arai, K.2    Takahashi, E.-I.3    Tanigami, A.4    Ohki, M.5
  • 88
    • 65249187743 scopus 로고    scopus 로고
    • In vitro activity of the EWS oncogene transcriptional activation domain
    • Ng, K. P., Li, K. K., and Lee, K. A. (2009). In vitro activity of the EWS oncogene transcriptional activation domain. Biochemistry 48, 2849-2857.
    • (2009) Biochemistry , vol.48 , pp. 2849-2857
    • Ng, K.P.1    Li, K.K.2    Lee, K.A.3
  • 90
    • 58549090731 scopus 로고    scopus 로고
    • Recent advances in the molecular pathology of soft tissue sarcoma: Implications for diagnosis, patient prognosis, and molecular target therapy in the future
    • Oda, Y., and Tsuneyoshi, M. (2009). Recent advances in the molecular pathology of soft tissue sarcoma: implications for diagnosis, patient prognosis, and molecular target therapy in the future. Cancer Sci. 100, 200-208.
    • (2009) Cancer Sci. , vol.100 , pp. 200-208
    • Oda, Y.1    Tsuneyoshi, M.2
  • 91
    • 0028074607 scopus 로고
    • The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains
    • Ohno, T., Ouchida, M., Lee, L., Gatalica, Z., Rao, V. N., and Reddy, E. S. (1994). The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains. Oncogene 9, 3087-3097. (Pubitemid 24296791)
    • (1994) Oncogene , vol.9 , Issue.10 , pp. 3087-3097
    • Ohno, T.1    Ouchida, M.2    Lee, L.3    Gatalica, Z.4    Rao, V.N.5    Reddy, E.S.P.6
  • 92
    • 0037448612 scopus 로고    scopus 로고
    • Molecular biology of the Ets family of transcription factors
    • DOI 10.1016/S0378-1119(02)01156-3
    • Oikawa, T., and Yamada, T. (2003). Molecular biology of the Ets family of transcription factors. Gene 303, 11-34. (Pubitemid 36151767)
    • (2003) Gene , vol.303 , Issue.1-2 , pp. 11-34
    • Oikawa, T.1    Yamada, T.2
  • 93
    • 0036276451 scopus 로고    scopus 로고
    • Molecular approaches to sarcoma therapy
    • DOI 10.1080/13577140220127530
    • Olsen, R. J., Tarantolo, S. R., and Hinrichs, S. H. (2002). Molecular approaches to sarcoma therapy. Sarcoma 6, 27-42. (Pubitemid 34620886)
    • (2002) Sarcoma , vol.6 , Issue.1 , pp. 27-42
    • Olsen, R.J.1    Tarantolo, S.R.2    Hinrichs, S.H.3
  • 95
    • 24344468254 scopus 로고    scopus 로고
    • Different methylation characteristics of protein arginine methyltransferase 1 and 3 toward the Ewing Sarcoma protein and a peptide
    • DOI 10.1002/prot.20579
    • Pahlich, S., Bschir, K., Chiavi, C., Belyanskaya, L., and Gehring, H. (2005). Different methylation characteristics of protein arginine methyltransferase 1 and 3 toward the Ewing sarcoma protein and a peptide. Proteins 61, 164-175. (Pubitemid 41262925)
    • (2005) Proteins: Structure, Function and Genetics , vol.61 , Issue.1 , pp. 164-175
    • Pahlich, S.1    Bschir, K.2    Chiavi, C.3    Belyanskaya, L.4    Gehring, H.5
  • 96
    • 51349117212 scopus 로고    scopus 로고
    • Identification of proteins interacting with protein arginine methyltransferase 8: The Ewing sarcoma (EWS) protein binds independent of its methylation state
    • Pahlich, S., Zakaryan, R. P., and Gehring, H. (2008). Identification of proteins interacting with protein arginine methyltransferase 8: the Ewing sarcoma (EWS) protein binds independent of its methylation state. Proteins 72, 1125-1137.
    • (2008) Proteins , vol.72 , pp. 1125-1137
    • Pahlich, S.1    Zakaryan, R.P.2    Gehring, H.3
  • 97
    • 0030610644 scopus 로고    scopus 로고
    • Characteristics sequence motifs at the breakpoints of the hybrid genes FUS/CHOP, EWS/CHOP and FUS/ERG in myxoid liposarcoma and acute myeloid leukemia
    • Panagopoulos, I., Lassen, C., Isaksson, M., Mitelman, F., Mandahl, N., and Aman, P. (1997). Characteristic sequence motifs at the breakpoints of the hybrid genes FUS/CHOP, EWS/CHOP and FUS/ERG in myxoid liposarcoma and acute myeloid leukemia. Oncogene 15, 1357-1362. (Pubitemid 27429752)
    • (1997) Oncogene , vol.15 , Issue.11 , pp. 1357-1362
    • Panagopoulos, I.1    Lassen, C.2    Isaksson, M.3    Mitelman, F.4    Mandahl, N.5    Aman, P.6
  • 98
    • 0033539921 scopus 로고    scopus 로고
    • Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t(9;17)(q22;q11)
    • Panagopoulos, I., Mencinger, M., Dietrich, C. U., Bjerkehagen, B., Saeter, G., Mertens, F., Mandahl, N., and Heim, S. (1999). Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t (9;17) (q22;q11). Oncogene 18, 7594-7598. (Pubitemid 30035061)
    • (1999) Oncogene , vol.18 , Issue.52 , pp. 7594-7598
    • Panagopoulos, I.1    Mencinger, M.2    Dietrich, C.U.3    Bjerkehagen, B.4    Saeter, G.5    Mertens, F.6    Mandahl, N.7    Heim, S.8
  • 101
  • 102
  • 103
    • 0032479980 scopus 로고    scopus 로고
    • TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL-mediated leukemogenesis
    • DOI 10.1093/emboj/17.15.4442
    • Perrotti, D., Bonatti, S., Trotta, R., Martinez, R., Skorski, T., Salomoni, P., Grassilli, E., Lozzo, R. V., Cooper, D. R., and Calabretta, B. (1998). TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL-mediated leukemogenesis. EMBO J. 17, 4442-4455. (Pubitemid 28362633)
    • (1998) EMBO Journal , vol.17 , Issue.15 , pp. 4442-4455
    • Perrotti, D.1    Bonatti, S.2    Trotta, R.3    Martinez, R.4    Skorski, T.5    Salomoni, P.6    Grassilli, E.7    Iozzo, R.V.8    Cooper, D.R.9    Calabretta, B.10
  • 104
  • 105
    • 0032490843 scopus 로고    scopus 로고
    • Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II
    • Petermann, R., Mossier, B. M., Aryee, D. N., Khazak, V., Golemis, E. A., and Kovar, H. (1998). Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II. Oncogene 17, 603-610. (Pubitemid 28401029)
    • (1998) Oncogene , vol.17 , Issue.5 , pp. 603-610
    • Petermann, R.1    Mossier, B.M.2    Aryee, D.N.T.3    Khazak, V.4    Golemis, E.A.5    Kovar, H.6
  • 106
    • 0027280280 scopus 로고
    • TFIIIA: Nine fingers-three hands?
    • Pieler, T., and Theunissen, O. (1993). TFIIIA: nine fingers-three hands? Trends Biochem. Sci. 18, 226-230.
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 226-230
    • Pieler, T.1    Theunissen, O.2
  • 107
    • 0031915988 scopus 로고    scopus 로고
    • TLS (translocated-in-liposarcoma) is a high-affinity interactor for steroid, thyroid hormone, and retinoid receptors
    • DOI 10.1210/me.12.1.4
    • Powers, C. A., Mathur, M., Raaka, B. M., Ron, D., and Samuels, H. H. (1998). TLS (translocated-in-liposarcoma) is a high-affinity interactor for steroid, thyroid hormone, and retinoid receptors. Mol. Endocrinol. 12, 4-18. (Pubitemid 28124775)
    • (1998) Molecular Endocrinology , vol.12 , Issue.1 , pp. 4-18
    • Powers, C.A.1    Mathur, M.2    Raaka, B.M.3    Ron, D.4    Samuels, H.H.5
  • 108
    • 3543026281 scopus 로고    scopus 로고
    • EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3
    • DOI 10.1128/MCB.24.16.7275-7283.2004
    • Prieur, A., Tirode, F., Cohen, P., and Delattre, O. (2004). EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3. Mol. Cell. Biol. 24, 7275-7283. (Pubitemid 39014452)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.16 , pp. 7275-7283
    • Prieur, A.1    Tirode, F.2    Cohen, P.3    Delattre, O.4
  • 109
    • 0027276357 scopus 로고
    • Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma
    • DOI 10.1038/ng0693-175
    • Rabbitts, T. H., Forster, A., Larson, R., and Nathan, P. (1993). Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t (12;16) in malignant liposarcoma. Nat. Genet. 4, 175-180. (Pubitemid 23179103)
    • (1993) Nature Genetics , vol.4 , Issue.2 , pp. 175-180
    • Rabbitts, T.H.1    Forster, A.2    Larson, R.3    Nathan, P.4
  • 110
    • 0036674269 scopus 로고    scopus 로고
    • Large-scale proteomic analysis of the human spliceosome
    • DOI 10.1101/gr.473902
    • Rappsilber, J., Ryder, U., Lamond, A. I., and Mann, M. (2002). Large-scale proteomic analysis of the human spliceosome. Genome Res. 12, 1231-1245. (Pubitemid 41264425)
    • (2002) Genome Research , vol.12 , Issue.8 , pp. 1231-1245
    • Rappsilber, J.1    Ryder, U.2    Lamond, A.I.3    Mann, M.4
  • 111
    • 0038000050 scopus 로고    scopus 로고
    • Detection of arginine dimethylated peptides by parallel precursor ion scanning mass spectrometry in positive ion mode
    • DOI 10.1021/ac026283q
    • Rappsilber, J., Friesen, W. J., Paushkin, S., Dreyfuss, G., and Mann, M. (2003). Detection of arginine dimethylated peptides by parallel precursor ion scanning mass spectrometry in positive ion mode. Anal. Chem. 75, 3107-3114. (Pubitemid 36830440)
    • (2003) Analytical Chemistry , vol.75 , Issue.13 , pp. 3107-3114
    • Rappsilber, J.1    Friesen, W.J.2    Paushkin, S.3    Dreyfuss, G.4    Mann, M.5
  • 112
    • 34548446433 scopus 로고    scopus 로고
    • Sarcomas: Genetics, signalling, and cellular origins. Part I: The fellowship of TET
    • DOI 10.1002/path.2209
    • Riggi, N., Cironi, L., Suva, M. L., and Stamenkovic, I. (2007). Sarcomas: genetics, signalling, and cellular origins. Part 1: the fellowship of TET. J. Pathol. 213, 4-20. (Pubitemid 47354561)
    • (2007) Journal of Pathology , vol.213 , Issue.1 , pp. 4-20
    • Riggi, N.1    Cironi, L.2    Suva, M.-L.3    Stamenkovic, I.4
  • 113
    • 34447324657 scopus 로고    scopus 로고
    • The Biology of Ewing sarcoma
    • DOI 10.1016/j.canlet.2006.12.009, PII S0304383506006811
    • Riggi, N., and Stamenkovic, I. (2007). The biology of Ewing sarcoma. Cancer Lett. 254, 1-10. (Pubitemid 47058800)
    • (2007) Cancer Letters , vol.254 , Issue.1 , pp. 1-10
    • Riggi, N.1    Stamenkovic, I.2
  • 114
    • 0035866778 scopus 로고    scopus 로고
    • The Ewing's sarcoma gene product functions as a transcriptional activator
    • Rossow, K. L., and Janknecht, R. (2001). The Ewing's sarcoma gene product functions as a transcriptional activator. Cancer Res. 61, 2690-2695. (Pubitemid 32685856)
    • (2001) Cancer Research , vol.61 , Issue.6 , pp. 2690-2695
    • Rossow, K.L.1    Janknecht, R.2
  • 117
    • 0036848091 scopus 로고    scopus 로고
    • The SR protein SRp38 represses splicing in M phase cells
    • DOI 10.1016/S0092-8674(02)01038-3
    • Shin, C., and Manley, J. L. (2002). The SR protein SRp38 represses splicing in M phase cells. Cell 111, 407-417. (Pubitemid 35341393)
    • (2002) Cell , vol.111 , Issue.3 , pp. 407-417
    • Shin, C.1    Manley, J.L.2
  • 118
    • 0345583702 scopus 로고    scopus 로고
    • Fusion of the EWS-related gene TAF2N to TEC in extraskeletal myxoid chondrosarcoma
    • Sjogren, H., Meis-Kindblom, J., Kindblom, L. G., Aman, P., and Stenman, G. (1999). Fusion of the EWS-related gene TAF2N to TEC in extraskeletal myxoid chondrosarcoma. Cancer Res. 59, 5064-5067. (Pubitemid 29503959)
    • (1999) Cancer Research , vol.59 , Issue.20 , pp. 5064-5067
    • Sjogren, H.1    Meis-Kindblom, J.2    Kindblom, L.-G.3    Aman, P.4    Stenman, G.5
  • 119
    • 33646366123 scopus 로고    scopus 로고
    • Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma
    • DOI 10.1016/j.ccr.2006.04.004, PII S1535610806001140
    • Smith, R., Owen, L. A., Trem, D. J., Wong, J. S., Whangbo, J. S., Golub, T. R., and Lessnick, S. L. (2006). Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma. Cancer Cell 9, 405-416. (Pubitemid 43668735)
    • (2006) Cancer Cell , vol.9 , Issue.5 , pp. 405-416
    • Smith, R.1    Owen, L.A.2    Trem, D.J.3    Wong, J.S.4    Whangbo, J.S.5    Golub, T.R.6    Lessnick, S.L.7
  • 120
    • 0035962649 scopus 로고    scopus 로고
    • Role of protein methylation in chromatin remodeling and transcriptional regulation
    • DOI 10.1038/sj.onc.1204325
    • Stallcup, M. R. (2001). Role of protein methylation in chromatin remodeling and transcriptional regulation. Oncogene 20, 3014-3020. (Pubitemid 32553555)
    • (2001) Oncogene , vol.20 , Issue.24 REV. ISS. 3 , pp. 3014-3020
    • Stallcup, M.R.1
  • 121
    • 0028968330 scopus 로고
    • Cabeza, a Drosophila gene encoding a novel RNA binding protein, shares homology with EWS and TLS, two genes involved in human sarcoma formation
    • Stolow, D. T., and Haynes, S. R. (1995). Cabeza, a Drosophila gene encoding a novel RNA binding protein, shares homology with EWS and TLS, two genes involved in human sarcoma formation. Nucleic Acids Res. 23, 835-843.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 835-843
    • Stolow, D.T.1    Haynes, S.R.2
  • 123
    • 0031025207 scopus 로고    scopus 로고
    • EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells
    • Tanaka, K., Iwakuma, T., Harimaya, K., Sato, H., and Iwamoto, Y. (1997). EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells. J. Clin. Invest. 99, 239-247. (Pubitemid 27053464)
    • (1997) Journal of Clinical Investigation , vol.99 , Issue.2 , pp. 239-247
    • Tanaka, K.1    Iwakuma, T.2    Harimaya, K.3    Sato, H.4    Iwamoto, Y.5
  • 124
    • 0344069652 scopus 로고    scopus 로고
    • Identification of genes differentially expressed in TLS-CHOP carrying myxoid liposarcomas
    • DOI 10.1002/(SICI)1097-0215(19990924)83:1<30::AID-IJC6>3.0.CO;2-4
    • Thelin-Jarnum, S., Lassen, C., Panagopoulos, I., Mandahl, N., and Aman, P. (1999). Identification of genes differentially expressed in TLS-CHOP carrying myxoid liposarcomas. Int. J. Cancer 83, 30-33. (Pubitemid 29409472)
    • (1999) International Journal of Cancer , vol.83 , Issue.1 , pp. 30-33
    • Thelin-Jarnum, S.1    Lassen, C.2    Panagopoulos, I.3    Mandahl, N.4    Aman, P.5
  • 125
    • 1842843228 scopus 로고    scopus 로고
    • The pro-oncoprotein EWS (Ewing's Sarcoma protein) interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription
    • Thomas, G. R., and Latchman, D. S. (2002). The pro-oncoprotein EWS (Ewing's Sarcoma protein) interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription. Cancer Biol. Ther. 1, 428-432.
    • (2002) Cancer Biol. Ther. , vol.1 , pp. 428-432
    • Thomas, G.R.1    Latchman, D.S.2
  • 126
    • 0030446259 scopus 로고    scopus 로고
    • EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FL11 fusion gene
    • Thompson, A. D., Braun, B. S., Arvand, A., Stewart, S. D., May, W. A., Chen, E., Korenberg, J., and Denny, C. (1996). EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI1 fusion gene. Oncogene 13, 2649-2658. (Pubitemid 27046120)
    • (1996) Oncogene , vol.13 , Issue.12 , pp. 2649-2658
    • Thompson, A.D.1    Braun, B.S.2    Arvand, A.3    Stewart, S.D.4    Mays, W.A.5    Chen, E.6    Korenberg, J.7    Denny, C.8
  • 127
    • 0037087628 scopus 로고    scopus 로고
    • A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription
    • DOI 10.1101/gad.976402
    • Tora, L. (2002). A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription. Genes Dev. 16, 673-675. (Pubitemid 34274035)
    • (2002) Genes and Development , vol.16 , Issue.6 , pp. 673-675
    • Tora, L.1
  • 128
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk, C., and Gold, L. (1990). Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249, 505-510.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 129
    • 6344280796 scopus 로고    scopus 로고
    • Recombinant EWS-FLI1 oncoprotein activates transcription
    • Uren, A., Tcherkasskaya, O., and Toretsky, J. A. (2004). Recombinant EWS-FLI1 oncoprotein activates transcription. Biochemistry 43, 13579-13589. (Pubitemid 39391158)
    • (2004) Biochemistry , vol.43 , Issue.42 , pp. 13579-13589
    • Uren, A.1    Tcherkasskaya, O.2    Toretsky, J.A.3
  • 131
    • 46649093597 scopus 로고    scopus 로고
    • Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription
    • DOI 10.1038/nature06992, PII NATURE06992
    • Wang, X., Arai, S., Song, X., Reichart, D., Du, K., Pascual, G., Tempst, P., Rosenfeld, M. G., Glass, C. K., and Kurokawa, R. (2008). Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature 454, 126-130. (Pubitemid 351934270)
    • (2008) Nature , vol.454 , Issue.7200 , pp. 126-130
    • Wang, X.1    Arai, S.2    Song, X.3    Reichart, D.4    Du, K.5    Pascual, G.6    Tempst, P.7    Rosenfeld, M.G.8    Glass, C.K.9    Kurokawa, R.10
  • 132
    • 0035834675 scopus 로고    scopus 로고
    • DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis
    • Welford, S. M., Hebert, S. P., Deneen, B., Arvand, A., and Denny, C. T. (2001). DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis. J. Biol. Chem. 276, 41977-41984.
    • (2001) J. Biol. Chem. , vol.276 , pp. 41977-41984
    • Welford, S.M.1    Hebert, S.P.2    Deneen, B.3    Arvand, A.4    Denny, C.T.5
  • 133
    • 0030855063 scopus 로고    scopus 로고
    • Identification of a human protein that recognizes the 3' splice site during the second step of pre-mRNA splicing
    • DOI 10.1093/emboj/16.14.4421
    • Wu, S., and Green, M. R. (1997). Identification of a human protein that recognizes the 30 splice site during the second step of pre-mRNA splicing. EMBO J. 16, 4421-4432. (Pubitemid 27298195)
    • (1997) EMBO Journal , vol.16 , Issue.14 , pp. 4421-4432
    • Wu, S.1    Green, M.R.2
  • 134
    • 27544471889 scopus 로고    scopus 로고
    • Chromosome translocations in sarcomas and the emergence of oncogenic transcription factors
    • DOI 10.1016/j.ejca.2005.08.003, PII S0959804905007033, Transcription Factors in Cancer
    • Xia, S. J., and Barr, F. G. (2005). Chromosome translocations in sarcomas and the emergence of oncogenic transcription factors. Eur. J. Cancer 41, 2513-2527. (Pubitemid 41540627)
    • (2005) European Journal of Cancer , vol.41 , Issue.16 , pp. 2513-2527
    • Xia, S.J.1    Barr, F.G.2
  • 135
    • 50449108097 scopus 로고    scopus 로고
    • Characteristic sequence motifs located at the genomic breakpoints of the translocation t (12;16) and t (12;22) in myxoid liposarcoma
    • Xiang, H., Wang, J., Hisaoka, M., and Zhu, X. (2008). Characteristic sequence motifs located at the genomic breakpoints of the translocation t (12;16) and t (12;22) in myxoid liposarcoma. Pathology 40, 547-552.
    • (2008) Pathology , vol.40 , pp. 547-552
    • Xiang, H.1    Wang, J.2    Hisaoka, M.3    Zhu, X.4
  • 136
    • 0032561190 scopus 로고    scopus 로고
    • Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing
    • DOI 10.1074/jbc.273.43.27761
    • Yang, L., Embree, L. J., Tsai, S., and Hickstein, D. D. (1998). Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing. J. Biol. Chem. 273, 27761-27764. (Pubitemid 28496059)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.43 , pp. 27761-27764
    • Yang, L.1    Embree, L.J.2    Tsai, S.3    Hickstein, D.D.4
  • 137
    • 0034353182 scopus 로고    scopus 로고
    • EWS. Fli-1 fusion protein interacts with hyperphosphorylated RNA polymerase II and interferes with serine-arginine protein-mediated RNA splicing
    • DOI 10.1074/jbc.M005739200
    • Yang, L., Chansky, H. A., and Hickstein, D. D. (2000a). EWS. Fli-1 fusion protein interacts with hyperphosphorylated RNA polymerase II and interferes with serine-arginine protein-mediated RNA splicing. J. Biol. Chem. 275, 37612-37618. (Pubitemid 32004872)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.48 , pp. 37612-37618
    • Yang, L.1    Chansky, H.A.2    Hickstein, D.D.3
  • 138
    • 0034053964 scopus 로고    scopus 로고
    • TLS-ERG leukemia fusion protein inhibits RNA splicing mediated by serine-arginine proteins
    • DOI 10.1128/MCB.20.10.3345-3354.2000
    • Yang, L., Embree, L. J., and Hickstein, D. D. (2000b). TLS-ERG leukemia fusion protein inhibits RNA splicing mediated by serine-arginine proteins. Mol. Cell. Biol. 20, 3345-3354. (Pubitemid 30243880)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.10 , pp. 3345-3354
    • Yang, L.1    Embree, L.J.2    Hickstein, D.D.3
  • 139
    • 0030894642 scopus 로고    scopus 로고
    • Inhibition of apoptosis by normal and aberrant Fli-1 and erg proteins involved in human solid tumors and leukemias
    • Yi, H., Fujimura, Y., Ouchida, M., Prasad, D. D., Rao, V. N., and Reddy, E. S. (1997). Inhibition of apoptosis by normal and aberrant Fli-1 and erg proteins involved in human solid tumors and leukemias. Oncogene 14, 1259-1268. (Pubitemid 27151983)
    • (1997) Oncogene , vol.14 , Issue.11 , pp. 1259-1268
    • Yi, H.-K.1    Fujimura, Y.2    Ouchida, M.3    Prasad, D.D.K.4    Rao, V.N.5    Reddy, E.S.P.6
  • 140
    • 52949092251 scopus 로고    scopus 로고
    • The DNA/RNA-binding protein, translin, binds microRNA122a and increases its in vivo stability
    • Yu, Z., and Hecht, N. B. (2008). The DNA/RNA-binding protein, translin, binds microRNA122a and increases its in vivo stability. J. Androl. 29, 572-579.
    • (2008) J. Androl. , vol.29 , pp. 572-579
    • Yu, Z.1    Hecht, N.B.2
  • 141
    • 0032541042 scopus 로고    scopus 로고
    • The transcriptional repressor, ZFM1 interacts with and modulates the ability of EWS to activate transcription
    • DOI 10.1074/jbc.273.29.18086
    • Zhang, D., Paley, A. J., and Childs, G. (1998). The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription. J. Biol. Chem. 273, 18086-18091. (Pubitemid 28334724)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.29 , pp. 18086-18091
    • Zhang, D.1    Paley, A.J.2    Childs, G.3
  • 142
    • 0035932382 scopus 로고    scopus 로고
    • An hsRPB4/7-dependent yeast assay for trans-activation by the EWS oncogene
    • DOI 10.1038/sj.onc.1204135
    • Zhou, H., and Lee, K. A. (2001). An hsRPB4/7-dependent yeast assay for transactivation by the EWS oncogene. Oncogene 20, 1519-1524. (Pubitemid 32291202)
    • (2001) Oncogene , vol.20 , Issue.12 , pp. 1519-1524
    • Zhou, H.1    Lee, K.A.W.2
  • 143
    • 0029834383 scopus 로고    scopus 로고
    • Tat-SF1: Cofactor for stimulation of transcriptional elongation by HIV- 1 Tat
    • DOI 10.1126/science.274.5287.605
    • Zhou, Q., and Sharp, P. A. (1996). Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat. Science 274, 605-610. (Pubitemid 26360439)
    • (1996) Science , vol.274 , Issue.5287 , pp. 605-610
    • Zhou, Q.1    Sharp, P.A.2
  • 144
    • 0037068447 scopus 로고    scopus 로고
    • Comprehensive proteomic analysis of the human spliceosome
    • DOI 10.1038/nature01031
    • Zhou, Z., Licklider, L. J., Gygi, S. P., and Reed, R. (2002). Comprehensive proteomic analysis of the human spliceosome. Nature 419, 182-185. (Pubitemid 35025448)
    • (2002) Nature , vol.419 , Issue.6903 , pp. 182-185
    • Zhou, Z.1    Licklider, L.J.2    Gygi, S.P.3    Reed, R.4
  • 145
    • 0027970712 scopus 로고
    • A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP
    • Zinszner, H., Albalat, R., and Ron, D. (1994). A novel effector domain
    • (1994) Genes and Development , vol.8 , Issue.21 , pp. 2513-2526
    • Zinszner, H.1    Albalat, R.2    Ron, D.3
  • 146
    • 0031035765 scopus 로고    scopus 로고
    • A topogenic role for the oncogenic N-terminus of TLS: Nucleolar localization when transcription is inhibited
    • Zinszner, H., Immanuel, D., Yin, Y., Liang, F. X., and Ron, D. (1997a). A topogenic role for the oncogenic N-terminus of TLS: nucleolar localization when transcription is inhibited. Oncogene 14, 451-461. (Pubitemid 27087108)
    • (1997) Oncogene , vol.14 , Issue.4 , pp. 451-461
    • Zinszner, H.1    Immanuel, D.2    Yin, Y.3    Liang, F.-X.4    Ron, D.5
  • 147
    • 0030746523 scopus 로고    scopus 로고
    • TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling
    • Zinszner, H., Sok, J., Immanuel, D., Yin, Y., and Ron, D. (1997b). TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling. J. Cell Sci. 110 (Pt 15), 1741-1750. (Pubitemid 27352853)
    • (1997) Journal of Cell Science , vol.110 , Issue.15 , pp. 1741-1750
    • Zinszner, H.1    Sok, J.2    Immanuel, D.3    Yin, Y.4    Ron, D.5


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