메뉴 건너뛰기




Volumn 34, Issue 2-3, 2013, Pages 719-734

Solute carriers (SLCs) in cancer

Author keywords

Cancer; Chemo sensitivity; Drug target; EMT; SLC; Solute carrier; Stem cells

Indexed keywords

ABC TRANSPORTER; AMINO ACID TRANSPORTER; CARRIER PROTEIN; DRUG CARRIER; SOLUTE CARRIER PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84875186877     PISSN: 00982997     EISSN: 18729452     Source Type: Journal    
DOI: 10.1016/j.mam.2012.12.007     Document Type: Review
Times cited : (60)

References (207)
  • 1
    • 34547763695 scopus 로고    scopus 로고
    • Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk
    • A. Agrawal, A. Guttapalli, S. Narayan, T.J. Albert, I.M. Shapiro, and M.V. Risbud Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk Am. J. Physiol. Cell. Physiol. 293 2 2007 C621 C631
    • (2007) Am. J. Physiol. Cell. Physiol. , vol.293 , Issue.2
    • Agrawal, A.1    Guttapalli, A.2    Narayan, S.3    Albert, T.J.4    Shapiro, I.M.5    Risbud, M.V.6
  • 3
    • 0030693281 scopus 로고    scopus 로고
    • Acute regulation of glucose transport in a monocyte-macrophage cell line: Glut-3 affinity for glucose is enhanced during the respiratory burst
    • N. Ahmed, M. Kansara, and M.V. Berridge Acute regulation of glucose transport in a monocyte-macrophage cell line: glut-3 affinity for glucose is enhanced during the respiratory burst Biochem. J. 327 Pt 2 1997 369 375
    • (1997) Biochem. J. , vol.327 , Issue.PART 2 , pp. 369-375
    • Ahmed, N.1    Kansara, M.2    Berridge, M.V.3
  • 5
    • 46449093702 scopus 로고    scopus 로고
    • In human entrocytes, GLN transport and ASCT2 surface expression induced by short-term EGF are MAPK, PI3K, and Rho-dependent
    • N.E. Avissar, H.C. Sax, and L. Toia In human entrocytes, GLN transport and ASCT2 surface expression induced by short-term EGF are MAPK, PI3K, and Rho-dependent Dig. Dis. Sci. 53 8 2008 2113 2125
    • (2008) Dig. Dis. Sci. , vol.53 , Issue.8 , pp. 2113-2125
    • Avissar, N.E.1    Sax, H.C.2    Toia, L.3
  • 6
    • 10644243391 scopus 로고    scopus 로고
    • Extracellular zinc triggers ERK-dependent activation of Na+/H+ exchange in colonocytes mediated by the zinc-sensing receptor
    • H. Azriel-Tamir, H. Sharir, B. Schwartz, and M. Hershfinkel Extracellular zinc triggers ERK-dependent activation of Na+/H+ exchange in colonocytes mediated by the zinc-sensing receptor J. Biol. Chem. 279 50 2004 51804 51816
    • (2004) J. Biol. Chem. , vol.279 , Issue.50 , pp. 51804-51816
    • Azriel-Tamir, H.1    Sharir, H.2    Schwartz, B.3    Hershfinkel, M.4
  • 7
    • 85027937938 scopus 로고    scopus 로고
    • Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate
    • E. Babu, S. Ramachandran, V. CoothanKandaswamy, S. Elangovan, P.D. Prasad, V. Ganapathy, and M. Thangaraju Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate Oncogene 30 38 2011 4026 4037
    • (2011) Oncogene , vol.30 , Issue.38 , pp. 4026-4037
    • Babu, E.1    Ramachandran, S.2    Coothankandaswamy, V.3    Elangovan, S.4    Prasad, P.D.5    Ganapathy, V.6    Thangaraju, M.7
  • 8
    • 33947420519 scopus 로고    scopus 로고
    • Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice
    • D.G. Bailey, G.K. Dresser, B.F. Leake, and R.B. Kim Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice Clin. Pharmacol. Ther. 81 4 2007 495 502
    • (2007) Clin. Pharmacol. Ther. , vol.81 , Issue.4 , pp. 495-502
    • Bailey, D.G.1    Dresser, G.K.2    Leake, B.F.3    Kim, R.B.4
  • 10
    • 34547133742 scopus 로고    scopus 로고
    • Hypoxic upregulation of glucose transporters in BeWo choriocarcinoma cells is mediated by hypoxia-inducible factor-1
    • M.U. Baumann, S. Zamudio, and N.P. Illsley Hypoxic upregulation of glucose transporters in BeWo choriocarcinoma cells is mediated by hypoxia-inducible factor-1 Am. J. Physiol. Cell. Physiol. 293 1 2007 C477 C485
    • (2007) Am. J. Physiol. Cell. Physiol. , vol.293 , Issue.1
    • Baumann, M.U.1    Zamudio, S.2    Illsley, N.P.3
  • 12
    • 0031563767 scopus 로고    scopus 로고
    • Influence of cycloheximide-mediated downregulation of glucose transport on TNF alpha-induced apoptosis
    • C. Binder, L. Binder, M. Kroemker, M. Schulz, and W. Hiddemann Influence of cycloheximide-mediated downregulation of glucose transport on TNF alpha-induced apoptosis Exp. Cell. Res. 236 1 1997 223 230
    • (1997) Exp. Cell. Res. , vol.236 , Issue.1 , pp. 223-230
    • Binder, C.1    Binder, L.2    Kroemker, M.3    Schulz, M.4    Hiddemann, W.5
  • 14
    • 27744570434 scopus 로고    scopus 로고
    • Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)
    • D.L. Bourdet, J.B. Pritchard, and D.R. Thakker Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3) J. Pharmacol. Exp. Ther. 315 3 2005 1288 1297
    • (2005) J. Pharmacol. Exp. Ther. , vol.315 , Issue.3 , pp. 1288-1297
    • Bourdet, D.L.1    Pritchard, J.B.2    Thakker, D.R.3
  • 16
    • 36248932713 scopus 로고    scopus 로고
    • The specific monocarboxylate transporter (MCT1) inhibitor, AR-C117977, a novel immunosuppressant, prolongs allograft survival in the mouse
    • V. Bueno, I. Binet, U. Steger, R. Bundick, D. Ferguson, C. Murray, D. Donald, and K. Wood The specific monocarboxylate transporter (MCT1) inhibitor, AR-C117977, a novel immunosuppressant, prolongs allograft survival in the mouse Transplantation 84 9 2007 1204 1207
    • (2007) Transplantation , vol.84 , Issue.9 , pp. 1204-1207
    • Bueno, V.1    Binet, I.2    Steger, U.3    Bundick, R.4    Ferguson, D.5    Murray, C.6    Donald, D.7    Wood, K.8
  • 17
    • 27644540271 scopus 로고    scopus 로고
    • Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers
    • C.I. Bungard, and J.D. McGivan Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers Arch. Biochem. Biophys. 443 1-2 2005 53 59
    • (2005) Arch. Biochem. Biophys. , vol.443 , Issue.12 , pp. 53-59
    • Bungard, C.I.1    McGivan, J.D.2
  • 18
  • 19
    • 33846270366 scopus 로고    scopus 로고
    • Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia
    • X. Cao, L. Fang, S. Gibbs, Y. Huang, Z. Dai, P. Wen, X. Zheng, W. Sadee, and D. Sun Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia Cancer Chemother. Pharmacol. 59 4 2007 495 505
    • (2007) Cancer Chemother. Pharmacol. , vol.59 , Issue.4 , pp. 495-505
    • Cao, X.1    Fang, L.2    Gibbs, S.3    Huang, Y.4    Dai, Z.5    Wen, P.6    Zheng, X.7    Sadee, W.8    Sun, D.9
  • 21
    • 33745358863 scopus 로고    scopus 로고
    • Increased NHE1 expression is associated with serum deprivation-induced differentiation in immortalized rat proximal tubule cells
    • L.R. Carraro-Lacroix, M.A. Ramirez, T.M. Zorn, N.A. Reboucas, and G. Malnic Increased NHE1 expression is associated with serum deprivation-induced differentiation in immortalized rat proximal tubule cells Am. J. Physiol. Renal Physiol. 291 1 2006 F129 F139
    • (2006) Am. J. Physiol. Renal Physiol. , vol.291 , Issue.1
    • Carraro-Lacroix, L.R.1    Ramirez, M.A.2    Zorn, T.M.3    Reboucas, N.A.4    Malnic, G.5
  • 22
    • 23944518640 scopus 로고    scopus 로고
    • Signal transduction mechanisms involved in the proliferation of C6 glioma cells induced by lysophosphatidic acid
    • S.R. Cechin, P.R. Dunkley, and R. Rodnight Signal transduction mechanisms involved in the proliferation of C6 glioma cells induced by lysophosphatidic acid Neurochem. Res. 30 5 2005 603 611
    • (2005) Neurochem. Res. , vol.30 , Issue.5 , pp. 603-611
    • Cechin, S.R.1    Dunkley, P.R.2    Rodnight, R.3
  • 23
    • 0036732041 scopus 로고    scopus 로고
    • The colon anion transporter, down-regulated in adenoma, induces growth suppression that is abrogated by E1A
    • J.M. Chapman, S.M. Knoepp, M.K. Byeon, K.W. Henderson, and C.W. Schweinfest The colon anion transporter, down-regulated in adenoma, induces growth suppression that is abrogated by E1A Cancer Res. 62 17 2002 5083 5088
    • (2002) Cancer Res. , vol.62 , Issue.17 , pp. 5083-5088
    • Chapman, J.M.1    Knoepp, S.M.2    Byeon, M.K.3    Henderson, K.W.4    Schweinfest, C.W.5
  • 25
    • 72249100798 scopus 로고    scopus 로고
    • Motor protein-dependent membrane trafficking of KCl cotransporter-4 is important for cancer cell invasion
    • Y.F. Chen, C.Y. Chou, R.J. Wilkins, J.C. Ellory, D.B. Mount, and M.R. Shen Motor protein-dependent membrane trafficking of KCl cotransporter-4 is important for cancer cell invasion Cancer Res. 69 22 2009 8585 8593
    • (2009) Cancer Res. , vol.69 , Issue.22 , pp. 8585-8593
    • Chen, Y.F.1    Chou, C.Y.2    Wilkins, R.J.3    Ellory, J.C.4    Mount, D.B.5    Shen, M.R.6
  • 26
    • 79953044882 scopus 로고    scopus 로고
    • HDAC inhibition decreases the expression of EGFR in colorectal cancer cells
    • C.W. Chou, M.S. Wu, W.C. Huang, and C.C. Chen HDAC inhibition decreases the expression of EGFR in colorectal cancer cells PLoS One 6 3 2011 e18087
    • (2011) PLoS One , vol.6 , Issue.3 , pp. 18087
    • Chou, C.W.1    Wu, M.S.2    Huang, W.C.3    Chen, C.C.4
  • 27
    • 79958040988 scopus 로고    scopus 로고
    • Berberine acutely activates the glucose transport activity of GLUT1
    • A. Cok, C. Plaisier, M.J. Salie, D.S. Oram, J. Chenge, and L.L. Louters Berberine acutely activates the glucose transport activity of GLUT1 Biochimie 93 7 2011 1187 1192
    • (2011) Biochimie , vol.93 , Issue.7 , pp. 1187-1192
    • Cok, A.1    Plaisier, C.2    Salie, M.J.3    Oram, D.S.4    Chenge, J.5    Louters, L.L.6
  • 28
    • 0027536484 scopus 로고
    • Kinetic analysis of the liver-type (GLUT2) and brain-type (GLUT3) glucose transporters in Xenopus oocytes: Substrate specificities and effects of transport inhibitors
    • C.A. Colville, M.J. Seatter, T.J. Jess, G.W. Gould, and H.M. Thomas Kinetic analysis of the liver-type (GLUT2) and brain-type (GLUT3) glucose transporters in Xenopus oocytes: substrate specificities and effects of transport inhibitors Biochem. J. 290 Pt 3 1993 701 706
    • (1993) Biochem. J. , vol.290 , Issue.PART 3 , pp. 701-706
    • Colville, C.A.1    Seatter, M.J.2    Jess, T.J.3    Gould, G.W.4    Thomas, H.M.5
  • 29
    • 0036078274 scopus 로고    scopus 로고
    • Physiological importance of system A-mediated amino acid transport to rat fetal development
    • S. Cramer, M. Beveridge, M. Kilberg, and D. Novak Physiological importance of system A-mediated amino acid transport to rat fetal development Am. J. Physiol. Cell. Physiol. 282 1 2002 C153 C160
    • (2002) Am. J. Physiol. Cell. Physiol. , vol.282 , Issue.1
    • Cramer, S.1    Beveridge, M.2    Kilberg, M.3    Novak, D.4
  • 31
    • 62549108159 scopus 로고    scopus 로고
    • ABC transporters, drug resistance, and cancer stem cells
    • M. Dean ABC transporters, drug resistance, and cancer stem cells J. Mammary Gland Biol. Neoplasia 14 1 2009 3 9
    • (2009) J. Mammary Gland Biol. Neoplasia , vol.14 , Issue.1 , pp. 3-9
    • Dean, M.1
  • 32
    • 58149380742 scopus 로고    scopus 로고
    • Stem cell concepts renew cancer research
    • J.E. Dick Stem cell concepts renew cancer research Blood 112 13 2008 4793 4807
    • (2008) Blood , vol.112 , Issue.13 , pp. 4793-4807
    • Dick, J.E.1
  • 36
    • 77954757238 scopus 로고    scopus 로고
    • Impact of system L amino acid transporter 1 (LAT1) on proliferation of human ovarian cancer cells: A possible target for combination therapy with anti-proliferative aminopeptidase inhibitors
    • X. Fan, D.D. Ross, H. Arakawa, V. Ganapathy, I. Tamai, and T. Nakanishi Impact of system L amino acid transporter 1 (LAT1) on proliferation of human ovarian cancer cells: a possible target for combination therapy with anti-proliferative aminopeptidase inhibitors Biochem. Pharmacol. 80 6 2010 811 818
    • (2010) Biochem. Pharmacol. , vol.80 , Issue.6 , pp. 811-818
    • Fan, X.1    Ross, D.D.2    Arakawa, H.3    Ganapathy, V.4    Tamai, I.5    Nakanishi, T.6
  • 37
    • 33751265334 scopus 로고    scopus 로고
    • IGF regulation of neutral amino acid transport in the BeWo choriocarcinoma cell line (b30 clone): Evidence for MAP kinase-dependent and MAP kinase-independent mechanisms
    • J. Fang, D. Mao, C.H. Smith, and M.E. Fant IGF regulation of neutral amino acid transport in the BeWo choriocarcinoma cell line (b30 clone): evidence for MAP kinase-dependent and MAP kinase-independent mechanisms Growth Horm. IGF Res. 16 5-6 2006 318 325
    • (2006) Growth Horm. IGF Res. , vol.16 , Issue.56 , pp. 318-325
    • Fang, J.1    Mao, D.2    Smith, C.H.3    Fant, M.E.4
  • 38
    • 33751091519 scopus 로고    scopus 로고
    • The H+-linked monocarboxylate transporter (MCT1/SLC16A1): A potential therapeutic target for high-risk neuroblastoma
    • J. Fang, Q.J. Quinones, T.L. Holman, M.J. Morowitz, Q. Wang, H. Zhao, F. Sivo, J.M. Maris, and M.L. Wahl The H+-linked monocarboxylate transporter (MCT1/SLC16A1): a potential therapeutic target for high-risk neuroblastoma Mol. Pharmacol. 70 6 2006 2108 2115
    • (2006) Mol. Pharmacol. , vol.70 , Issue.6 , pp. 2108-2115
    • Fang, J.1    Quinones, Q.J.2    Holman, T.L.3    Morowitz, M.J.4    Wang, Q.5    Zhao, H.6    Sivo, F.7    Maris, J.M.8    Wahl, M.L.9
  • 39
    • 0036720332 scopus 로고    scopus 로고
    • Direct effect of zinc on mitochondrial apoptogenesis in prostate cells
    • P. Feng, T.L. Li, Z.X. Guan, R.B. Franklin, and L.C. Costello Direct effect of zinc on mitochondrial apoptogenesis in prostate cells Prostate 52 4 2002 311 318
    • (2002) Prostate , vol.52 , Issue.4 , pp. 311-318
    • Feng, P.1    Li, T.L.2    Guan, Z.X.3    Franklin, R.B.4    Costello, L.C.5
  • 41
    • 77954853506 scopus 로고    scopus 로고
    • Research resource. expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene
    • C.E. Foulds, A. Tsimelzon, W. Long, A. Le, S.Y. Tsai, M.J. Tsai, and B.W. O'Malley Research resource. expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene Mol. Endocrinol. 24 5 2010 1090 1105
    • (2010) Mol. Endocrinol. , vol.24 , Issue.5 , pp. 1090-1105
    • Foulds, C.E.1    Tsimelzon, A.2    Long, W.3    Le, A.4    Tsai, S.Y.5    Tsai, M.J.6    O'Malley, B.W.7
  • 43
    • 65349136466 scopus 로고    scopus 로고
    • The important role of the apoptotic effects of zinc in the development of cancers
    • R.B. Franklin, and L.C. Costello The important role of the apoptotic effects of zinc in the development of cancers J. Cell Biochem. 106 5 2009 750 757
    • (2009) J. Cell Biochem. , vol.106 , Issue.5 , pp. 750-757
    • Franklin, R.B.1    Costello, L.C.2
  • 44
    • 23044474905 scopus 로고    scopus 로고
    • Amino acid transporters ASCT2 and LAT1 in cancer: Partners in crime?
    • B.C. Fuchs, and B.P. Bode Amino acid transporters ASCT2 and LAT1 in cancer: partners in crime? Semin Cancer Biol. 15 2005 254 266
    • (2005) Semin Cancer Biol. , vol.15 , pp. 254-266
    • Fuchs, B.C.1    Bode, B.P.2
  • 45
    • 58649091122 scopus 로고    scopus 로고
    • Functional association between K+-Cl- cotransporter-4 and H+, K+-ATPase in the apical canalicular membrane of gastric parietal cells
    • T. Fujii, Y. Takahashi, A. Ikari, M. Morii, Y. Tabuchi, K. Tsukada, N. Takeguchi, and H. Sakai Functional association between K+-Cl- cotransporter-4 and H+, K+-ATPase in the apical canalicular membrane of gastric parietal cells J. Biol. Chem. 284 1 2009 619 629
    • (2009) J. Biol. Chem. , vol.284 , Issue.1 , pp. 619-629
    • Fujii, T.1    Takahashi, Y.2    Ikari, A.3    Morii, M.4    Tabuchi, Y.5    Tsukada, K.6    Takeguchi, N.7    Sakai, H.8
  • 46
    • 33745838924 scopus 로고    scopus 로고
    • Amino acid starvation induces the SNAT2 neutral amino acid transporter by a mechanism that involves eukaryotic initiation factor 2alpha phosphorylation and cap-independent translation
    • F. Gaccioli, C.C. Huang, C. Wang, E. Bevilacqua, R. Franchi-Gazzola, G.C. Gazzola, O. Bussolati, M.D. Snider, and M. Hatzoglou Amino acid starvation induces the SNAT2 neutral amino acid transporter by a mechanism that involves eukaryotic initiation factor 2alpha phosphorylation and cap-independent translation J. Biol. Chem. 281 26 2006 17929 17940
    • (2006) J. Biol. Chem. , vol.281 , Issue.26 , pp. 17929-17940
    • Gaccioli, F.1    Huang, C.C.2    Wang, C.3    Bevilacqua, E.4    Franchi-Gazzola, R.5    Gazzola, G.C.6    Bussolati, O.7    Snider, M.D.8    Hatzoglou, M.9
  • 47
    • 65249168811 scopus 로고    scopus 로고
    • Interaction of monocarboxylate transporter 4 with beta1-integrin and its role in cell migration
    • S.M. Gallagher, J.J. Castorino, and N.J. Philp Interaction of monocarboxylate transporter 4 with beta1-integrin and its role in cell migration Am. J. Physiol. Cell. Physiol. 296 3 2009 C414 C421
    • (2009) Am. J. Physiol. Cell. Physiol. , vol.296 , Issue.3
    • Gallagher, S.M.1    Castorino, J.J.2    Philp, N.J.3
  • 48
    • 34249293335 scopus 로고    scopus 로고
    • Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231
    • S.M. Gallagher, J.J. Castorino, D. Wang, and N.J. Philp Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231 Cancer Res. 67 9 2007 4182 4189
    • (2007) Cancer Res. , vol.67 , Issue.9 , pp. 4182-4189
    • Gallagher, S.M.1    Castorino, J.J.2    Wang, D.3    Philp, N.J.4
  • 50
    • 57749111596 scopus 로고    scopus 로고
    • Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond
    • V. Ganapathy, M. Thangaraju, and P.D. Prasad Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond Pharmacol. Ther. 121 1 2009 29 40
    • (2009) Pharmacol. Ther. , vol.121 , Issue.1 , pp. 29-40
    • Ganapathy, V.1    Thangaraju, M.2    Prasad, P.D.3
  • 51
    • 0029971428 scopus 로고    scopus 로고
    • Cellular pH gradient in tumor versus normal tissue: Potential exploitation for the treatment of cancer
    • L.E. Gerweck, and K. Seetharaman Cellular pH gradient in tumor versus normal tissue: potential exploitation for the treatment of cancer Cancer Res. 56 6 1996 1194 1198
    • (1996) Cancer Res. , vol.56 , Issue.6 , pp. 1194-1198
    • Gerweck, L.E.1    Seetharaman, K.2
  • 52
    • 55549114713 scopus 로고    scopus 로고
    • Despite increased ATF4 binding at the C/EBP-ATF composite site following activation of the unfolded protein response, system A transporter 2 (SNAT2) transcription activity is repressed in HepG2 cells
    • A. Gjymishka, S.S. Palii, J. Shan, and M.S. Kilberg Despite increased ATF4 binding at the C/EBP-ATF composite site following activation of the unfolded protein response, system A transporter 2 (SNAT2) transcription activity is repressed in HepG2 cells J. Biol. Chem. 283 41 2008 27736 27747
    • (2008) J. Biol. Chem. , vol.283 , Issue.41 , pp. 27736-27747
    • Gjymishka, A.1    Palii, S.S.2    Shan, J.3    Kilberg, M.S.4
  • 53
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • M.M. Gottesman, T. Fojo, and S.E. Bates Multidrug resistance in cancer: role of ATP-dependent transporters Nat. Rev. Cancer 2 1 2002 48 58
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.1 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 54
    • 0034772516 scopus 로고    scopus 로고
    • Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)- cystine transporter: A new action for an old drug
    • P.W. Gout, A.R. Buckley, C.R. Simms, and N. Bruchovsky Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)- cystine transporter: a new action for an old drug Leukemia 15 10 2001 1633 1640
    • (2001) Leukemia , vol.15 , Issue.10 , pp. 1633-1640
    • Gout, P.W.1    Buckley, A.R.2    Simms, C.R.3    Bruchovsky, N.4
  • 55
  • 57
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • P.B. Gupta, T.T. Onder, G. Jiang, K. Tao, C. Kuperwasser, R.A. Weinberg, and E.S. Lander Identification of selective inhibitors of cancer stem cells by high-throughput screening Cell 138 4 2009 645 659
    • (2009) Cell , vol.138 , Issue.4 , pp. 645-659
    • Gupta, P.B.1    Onder, T.T.2    Jiang, G.3    Tao, K.4    Kuperwasser, C.5    Weinberg, R.A.6    Lander, E.S.7
  • 58
    • 77954355480 scopus 로고    scopus 로고
    • Inhibition of the Sodium-Potassium-Chloride Cotransporter Isoform-1 reduces glioma invasion
    • B.R. Haas, and H. Sontheimer Inhibition of the Sodium-Potassium-Chloride Cotransporter Isoform-1 reduces glioma invasion Cancer Res. 70 13 2010 5597 5606
    • (2010) Cancer Res. , vol.70 , Issue.13 , pp. 5597-5606
    • Haas, B.R.1    Sontheimer, H.2
  • 59
    • 0032578681 scopus 로고    scopus 로고
    • Hyperglycemia regulates the glucose-transport system of clonal choriocarcinoma cells in vitro. A potential molecular mechanism contributing to the adjunct effect of glucose in tumor therapy
    • T. Hahn, S. Barth, W. Hofmann, O. Reich, I. Lang, and G. Desoye Hyperglycemia regulates the glucose-transport system of clonal choriocarcinoma cells in vitro. A potential molecular mechanism contributing to the adjunct effect of glucose in tumor therapy Int. J. Cancer 78 3 1998 353 360
    • (1998) Int. J. Cancer , vol.78 , Issue.3 , pp. 353-360
    • Hahn, T.1    Barth, S.2    Hofmann, W.3    Reich, O.4    Lang, I.5    Desoye, G.6
  • 60
    • 34548835242 scopus 로고    scopus 로고
    • Effect of Cl- on tyrosinase: Complex inhibition kinetics and biochemical implication
    • H.Y. Han, J.R. Lee, W.A. Xu, M.J. Hahn, J.M. Yang, and Y.D. Park Effect of Cl- on tyrosinase: complex inhibition kinetics and biochemical implication J. Biomol. Struct. Dyn. 25 2 2007 165 171
    • (2007) J. Biomol. Struct. Dyn. , vol.25 , Issue.2 , pp. 165-171
    • Han, H.Y.1    Lee, J.R.2    Xu, W.A.3    Hahn, M.J.4    Yang, J.M.5    Park, Y.D.6
  • 61
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 1 2000 57 70
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 62
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 5 2011 646 674
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 63
    • 77957234813 scopus 로고    scopus 로고
    • Co-expression of CD147 (EMMPRIN), CD44v3-10, MDR1 and monocarboxylate transporters is associated with prostate cancer drug resistance and progression
    • J. Hao, H. Chen, M.C. Madigan, P.J. Cozzi, J. Beretov, W. Xiao, W.J. Delprado, P.J. Russell, and Y. Li Co-expression of CD147 (EMMPRIN), CD44v3-10, MDR1 and monocarboxylate transporters is associated with prostate cancer drug resistance and progression Br. J. Cancer 103 7 2010 1008 1018
    • (2010) Br. J. Cancer , vol.103 , Issue.7 , pp. 1008-1018
    • Hao, J.1    Chen, H.2    Madigan, M.C.3    Cozzi, P.J.4    Beretov, J.5    Xiao, W.6    Delprado, W.J.7    Russell, P.J.8    Li, Y.9
  • 65
    • 79952277323 scopus 로고    scopus 로고
    • Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes
    • J.C. Hartman, K. Brouwer, A. Mandagere, L. Melvin, and R. Gorczynski Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes Can. J. Physiol. Pharmacol. 88 6 2010 682 691
    • (2010) Can. J. Physiol. Pharmacol. , vol.88 , Issue.6 , pp. 682-691
    • Hartman, J.C.1    Brouwer, K.2    Mandagere, A.3    Melvin, L.4    Gorczynski, R.5
  • 66
    • 33846003862 scopus 로고    scopus 로고
    • Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2
    • T. Hatanaka, Y. Hatanaka, and M. Setou Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2 J. Biol. Chem. 281 47 2006 35922 35930
    • (2006) J. Biol. Chem. , vol.281 , Issue.47 , pp. 35922-35930
    • Hatanaka, T.1    Hatanaka, Y.2    Setou, M.3
  • 67
    • 18044372809 scopus 로고    scopus 로고
    • Identification and characterisation of a new class of highly specific and potent inhibitors of the mitochondrial pyruvate carrier
    • J.C. Hildyard, C. Ammala, I.D. Dukes, S.A. Thomson, and A.P. Halestrap Identification and characterisation of a new class of highly specific and potent inhibitors of the mitochondrial pyruvate carrier Biochim. Biophys. Acta 1707 2-3 2005 221 230
    • (2005) Biochim. Biophys. Acta , vol.1707 , Issue.23 , pp. 221-230
    • Hildyard, J.C.1    Ammala, C.2    Dukes, I.D.3    Thomson, S.A.4    Halestrap, A.P.5
  • 68
    • 0034779753 scopus 로고    scopus 로고
    • Common mechanisms of inhibition for the Na+/glucose (hSGLT1) and Na+/Cl-/GABA (hGAT1) cotransporters
    • B.A. Hirayama, A. Diez-Sampedro, and E.M. Wright Common mechanisms of inhibition for the Na+/glucose (hSGLT1) and Na+/Cl-/GABA (hGAT1) cotransporters Br. J. Pharmacol. 134 3 2001 484 495
    • (2001) Br. J. Pharmacol. , vol.134 , Issue.3 , pp. 484-495
    • Hirayama, B.A.1    Diez-Sampedro, A.2    Wright, E.M.3
  • 69
    • 52649107626 scopus 로고    scopus 로고
    • Cancer cell metabolism: Warburg and beyond
    • P.P. Hsu, and D.M. Sabatini Cancer cell metabolism: Warburg and beyond Cell 134 5 2008 703 707
    • (2008) Cell , vol.134 , Issue.5 , pp. 703-707
    • Hsu, P.P.1    Sabatini, D.M.2
  • 70
    • 36349005441 scopus 로고    scopus 로고
    • KCl cotransporter-3 down-regulates E-cadherin/beta-catenin complex to promote epithelial-mesenchymal transition
    • Y.M. Hsu, Y.F. Chen, C.Y. Chou, M.J. Tang, J.H. Chen, R.J. Wilkins, J.C. Ellory, and M.R. Shen KCl cotransporter-3 down-regulates E-cadherin/beta-catenin complex to promote epithelial-mesenchymal transition Cancer Res. 67 22 2007 11064 11073
    • (2007) Cancer Res. , vol.67 , Issue.22 , pp. 11064-11073
    • Hsu, Y.M.1    Chen, Y.F.2    Chou, C.Y.3    Tang, M.J.4    Chen, J.H.5    Wilkins, R.J.6    Ellory, J.C.7    Shen, M.R.8
  • 71
    • 33846602260 scopus 로고    scopus 로고
    • IGF-1 upregulates electroneutral K-Cl cotransporter KCC3 and KCC4 which are differentially required for breast cancer cell proliferation and invasiveness
    • Y.M. Hsu, C.Y. Chou, H.H. Chen, W.Y. Lee, Y.F. Chen, P.W. Lin, S.L. Alper, J.C. Ellory, and M.R. Shen IGF-1 upregulates electroneutral K-Cl cotransporter KCC3 and KCC4 which are differentially required for breast cancer cell proliferation and invasiveness J. Cell Physiol. 210 3 2007 626 636
    • (2007) J. Cell Physiol. , vol.210 , Issue.3 , pp. 626-636
    • Hsu, Y.M.1    Chou, C.Y.2    Chen, H.H.3    Lee, W.Y.4    Chen, Y.F.5    Lin, P.W.6    Alper, S.L.7    Ellory, J.C.8    Shen, M.R.9
  • 72
    • 23844486685 scopus 로고    scopus 로고
    • Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance
    • Y. Huang, Z. Dai, C. Barbacioru, and W. Sadee Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance Cancer Res. 65 16 2005 7446 7454
    • (2005) Cancer Res. , vol.65 , Issue.16 , pp. 7446-7454
    • Huang, Y.1    Dai, Z.2    Barbacioru, C.3    Sadee, W.4
  • 73
    • 33745699234 scopus 로고    scopus 로고
    • Membrane transporters and channels in chemoresistance and -sensitivity of tumor cells
    • Y. Huang, and W. Sadee Membrane transporters and channels in chemoresistance and -sensitivity of tumor cells Cancer Lett. 239 2 2006 168 182
    • (2006) Cancer Lett. , vol.239 , Issue.2 , pp. 168-182
    • Huang, Y.1    Sadee, W.2
  • 75
    • 0037134492 scopus 로고    scopus 로고
    • Insulin promotes the cell surface recruitment of the SAT2/ATA2 system A amino acid transporter from an endosomal compartment in skeletal muscle cells
    • R. Hyde, K. Peyrollier, and H.S. Hundal Insulin promotes the cell surface recruitment of the SAT2/ATA2 system A amino acid transporter from an endosomal compartment in skeletal muscle cells J. Biol. Chem. 277 16 2002 13628 13634
    • (2002) J. Biol. Chem. , vol.277 , Issue.16 , pp. 13628-13634
    • Hyde, R.1    Peyrollier, K.2    Hundal, H.S.3
  • 77
    • 78650514267 scopus 로고    scopus 로고
    • Prediction of fluoroquinolone-induced elevation in serum creatinine levels: A case of drug-endogenous substance interaction involving the inhibition of renal secretion
    • Y. Imamura, N. Murayama, N. Okudaira, A. Kurihara, O. Okazaki, T. Izumi, K. Inoue, H. Yuasa, H. Kusuhara, and Y. Sugiyama Prediction of fluoroquinolone-induced elevation in serum creatinine levels: a case of drug-endogenous substance interaction involving the inhibition of renal secretion Clin. Pharmacol. Ther. 89 1 2011 81 88
    • (2011) Clin. Pharmacol. Ther. , vol.89 , Issue.1 , pp. 81-88
    • Imamura, Y.1    Murayama, N.2    Okudaira, N.3    Kurihara, A.4    Okazaki, O.5    Izumi, T.6    Inoue, K.7    Yuasa, H.8    Kusuhara, H.9    Sugiyama, Y.10
  • 78
    • 67349276648 scopus 로고    scopus 로고
    • Isolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers
    • S. Irshad, A.L. Mahul-Mellier, N. Kassouf, A. Lemarie, and S. Grimm Isolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers Cell Death Differ. 16 2009 890 898
    • (2009) Cell Death Differ. , vol.16 , pp. 890-898
    • Irshad, S.1    Mahul-Mellier, A.L.2    Kassouf, N.3    Lemarie, A.4    Grimm, S.5
  • 81
    • 34147126803 scopus 로고    scopus 로고
    • Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells
    • N. Kagara, N. Tanaka, S. Noguchi, and T. Hirano Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells Cancer Sci. 98 5 2007 692 697
    • (2007) Cancer Sci. , vol.98 , Issue.5 , pp. 692-697
    • Kagara, N.1    Tanaka, N.2    Noguchi, S.3    Hirano, T.4
  • 82
    • 0347949547 scopus 로고    scopus 로고
    • Regulation of cell cycle progression by calcium/calmodulin-dependent pathways
    • C.R. Kahl, and A.R. Means Regulation of cell cycle progression by calcium/calmodulin-dependent pathways Endocr. Rev. 24 6 2003 719 736
    • (2003) Endocr. Rev. , vol.24 , Issue.6 , pp. 719-736
    • Kahl, C.R.1    Means, A.R.2
  • 83
    • 33750442920 scopus 로고    scopus 로고
    • Kinetics of glial glutamine efflux and the mechanism of neuronal uptake studied in vivo in mildly hyperammonemic rat brain
    • K. Kanamori, and B.D. Ross Kinetics of glial glutamine efflux and the mechanism of neuronal uptake studied in vivo in mildly hyperammonemic rat brain J. Neurochem. 99 4 2006 1103 1113
    • (2006) J. Neurochem. , vol.99 , Issue.4 , pp. 1103-1113
    • Kanamori, K.1    Ross, B.D.2
  • 84
    • 79953893349 scopus 로고    scopus 로고
    • B-Raf associates with and activates the NHE1 isoform of the Na+/H+ exchanger
    • P. Karki, X. Li, D. Schrama, and L. Fliegel B-Raf associates with and activates the NHE1 isoform of the Na+/H+ exchanger J. Biol. Chem. 286 15 2011 13096 13105
    • (2011) J. Biol. Chem. , vol.286 , Issue.15 , pp. 13096-13105
    • Karki, P.1    Li, X.2    Schrama, D.3    Fliegel, L.4
  • 86
    • 52449118755 scopus 로고    scopus 로고
    • Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy
    • S. Karunakaran, N.S. Umapathy, M. Thangaraju, T. Hatanaka, S. Itagaki, D.H. Munn, P.D. Prasad, and V. Ganapathy Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy Biochem. J. 414 3 2008 343 355
    • (2008) Biochem. J. , vol.414 , Issue.3 , pp. 343-355
    • Karunakaran, S.1    Umapathy, N.S.2    Thangaraju, M.3    Hatanaka, T.4    Itagaki, S.5    Munn, D.H.6    Prasad, P.D.7    Ganapathy, V.8
  • 87
    • 0032143957 scopus 로고    scopus 로고
    • Unique mechanism of GLUT3 glucose transporter regulation by prolonged energy demand: Increased protein half-life
    • Z.A. Khayat, A.L. McCall, and A. Klip Unique mechanism of GLUT3 glucose transporter regulation by prolonged energy demand: increased protein half-life Biochem. J. 333 Pt 3 1998 713 718
    • (1998) Biochem. J. , vol.333 , Issue.PART 3 , pp. 713-718
    • Khayat, Z.A.1    McCall, A.L.2    Klip, A.3
  • 88
    • 45749107547 scopus 로고    scopus 로고
    • BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells
    • C.S. Kim, S.H. Cho, H.S. Chun, S.Y. Lee, H. Endou, Y. Kanai, and K. Kim do BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells Biol. Pharm. Bull. 31 6 2008 1096 1100
    • (2008) Biol. Pharm. Bull. , vol.31 , Issue.6 , pp. 1096-1100
    • Kim, C.S.1    Cho, S.H.2    Chun, H.S.3    Lee, S.Y.4    Endou, H.5    Kanai, Y.6    Kim Do, K.7
  • 89
    • 84934442867 scopus 로고    scopus 로고
    • Characterization of taurine as inhibitor of sodium glucose transporter
    • H.W. Kim, A.J. Lee, S. You, T. Park, and D.H. Lee Characterization of taurine as inhibitor of sodium glucose transporter Adv. Exp. Med. Biol. 583 2006 137 145
    • (2006) Adv. Exp. Med. Biol. , vol.583 , pp. 137-145
    • Kim, H.W.1    Lee, A.J.2    You, S.3    Park, T.4    Lee, D.H.5
  • 90
    • 79956099278 scopus 로고    scopus 로고
    • Influence of non-steroidal anti-inflammatory drugs on organic anion transporting polypeptide (OATP) 1B1- and OATP1B3-mediated drug transport
    • J. Kindla, F. Muller, M. Mieth, M.F. Fromm, and J. Konig Influence of non-steroidal anti-inflammatory drugs on organic anion transporting polypeptide (OATP) 1B1- and OATP1B3-mediated drug transport Drug Metab. Dispos. 39 6 2011 1047 1053
    • (2011) Drug Metab. Dispos. , vol.39 , Issue.6 , pp. 1047-1053
    • Kindla, J.1    Muller, F.2    Mieth, M.3    Fromm, M.F.4    Konig, J.5
  • 93
    • 33845697112 scopus 로고    scopus 로고
    • Inhibition of the Na+-H+ exchanger isoform-1 and the extracellular signal-regulated kinase induces apoptosis: A time course of events
    • D. Konstantinidis, G. Koliakos, K. Vafia, P. Liakos, C. Bantekas, V. Trachana, and M. Kaloyianni Inhibition of the Na+-H+ exchanger isoform-1 and the extracellular signal-regulated kinase induces apoptosis: a time course of events Cell Physiol. Biochem. 18 4-5 2006 211 222
    • (2006) Cell Physiol. Biochem. , vol.18 , Issue.45 , pp. 211-222
    • Konstantinidis, D.1    Koliakos, G.2    Vafia, K.3    Liakos, P.4    Bantekas, C.5    Trachana, V.6    Kaloyianni, M.7
  • 94
    • 79955398591 scopus 로고    scopus 로고
    • Otto Warburg's contributions to current concepts of cancer metabolism
    • W.H. Koppenol, P.L. Bounds, and C.V. Dang Otto Warburg's contributions to current concepts of cancer metabolism Nat. Rev. Cancer 11 5 2011 325 337
    • (2011) Nat. Rev. Cancer , vol.11 , Issue.5 , pp. 325-337
    • Koppenol, W.H.1    Bounds, P.L.2    Dang, C.V.3
  • 95
    • 59849096790 scopus 로고    scopus 로고
    • Molecular and functional characterization of choline transporter in human colon carcinoma HT-29 cells
    • H. Kouji, M. Inazu, T. Yamada, H. Tajima, T. Aoki, and T. Matsumiya Molecular and functional characterization of choline transporter in human colon carcinoma HT-29 cells Arch. Biochem. Biophys. 483 1 2009 90 98
    • (2009) Arch. Biochem. Biophys. , vol.483 , Issue.1 , pp. 90-98
    • Kouji, H.1    Inazu, M.2    Yamada, T.3    Tajima, H.4    Aoki, T.5    Matsumiya, T.6
  • 96
    • 67650654399 scopus 로고    scopus 로고
    • Ability of sat-1 to transport sulfate, bicarbonate, or oxalate under physiological conditions
    • W. Krick, N. Schnedler, G. Burckhardt, and B.C. Burckhardt Ability of sat-1 to transport sulfate, bicarbonate, or oxalate under physiological conditions Am. J. Physiol. Renal Physiol. 297 1 2009 F145 F154
    • (2009) Am. J. Physiol. Renal Physiol. , vol.297 , Issue.1
    • Krick, W.1    Schnedler, N.2    Burckhardt, G.3    Burckhardt, B.C.4
  • 97
    • 44449147036 scopus 로고    scopus 로고
    • Tumor cell metabolism: Cancer's Achilles' heel
    • G. Kroemer, and J. Pouyssegur Tumor cell metabolism: cancer's Achilles' heel Cancer Cell 13 6 2008 472 482
    • (2008) Cancer Cell , vol.13 , Issue.6 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 98
    • 72249121406 scopus 로고    scopus 로고
    • Repression of NHE1 expression by PPARgamma activation is a potential new approach for specific inhibition of the growth of tumor cells in vitro and in vivo
    • A.P. Kumar, A.L. Quake, M.K. Chang, T. Zhou, K.S. Lim, R. Singh, R.E. Hewitt, M. Salto-Tellez, S. Pervaiz, and M.V. Clement Repression of NHE1 expression by PPARgamma activation is a potential new approach for specific inhibition of the growth of tumor cells in vitro and in vivo Cancer Res. 69 22 2009 8636 8644
    • (2009) Cancer Res. , vol.69 , Issue.22 , pp. 8636-8644
    • Kumar, A.P.1    Quake, A.L.2    Chang, M.K.3    Zhou, T.4    Lim, K.S.5    Singh, R.6    Hewitt, R.E.7    Salto-Tellez, M.8    Pervaiz, S.9    Clement, M.V.10
  • 99
    • 79954581807 scopus 로고    scopus 로고
    • Vitamin D3 restores altered cholinergic and insulin receptor expression in the cerebral cortex and muscarinic M3 receptor expression in pancreatic islets of streptozotocin induced diabetic rats
    • P.T. Kumar, S. Antony, M.S. Nandhu, J. Sadanandan, G. Naijil, and C.S. Paulose Vitamin D3 restores altered cholinergic and insulin receptor expression in the cerebral cortex and muscarinic M3 receptor expression in pancreatic islets of streptozotocin induced diabetic rats J. Nutr. Biochem. 22 5 2011 418 425
    • (2011) J. Nutr. Biochem. , vol.22 , Issue.5 , pp. 418-425
    • Kumar, P.T.1    Antony, S.2    Nandhu, M.S.3    Sadanandan, J.4    Naijil, G.5    Paulose, C.S.6
  • 100
    • 69549111106 scopus 로고    scopus 로고
    • Dietary protein intake and stage of lactation differentially modulate amino acid transporter mRNA abundance in porcine mammary tissue
    • J.P. Laspiur, J.L. Burton, P.S. Weber, J. Moore, R.N. Kirkwood, and N.L. Trottier Dietary protein intake and stage of lactation differentially modulate amino acid transporter mRNA abundance in porcine mammary tissue J. Nutr. 139 9 2009 1677 1684
    • (2009) J. Nutr. , vol.139 , Issue.9 , pp. 1677-1684
    • Laspiur, J.P.1    Burton, J.L.2    Weber, P.S.3    Moore, J.4    Kirkwood, R.N.5    Trottier, N.L.6
  • 101
    • 37549011780 scopus 로고    scopus 로고
    • XCT expression reduces the early cell cycle requirement for calcium signaling
    • M. Lastro, A. Kourtidis, K. Farley, and D.S. Conklin XCT expression reduces the early cell cycle requirement for calcium signaling Cell. Signal. 20 2 2008 390 399
    • (2008) Cell. Signal. , vol.20 , Issue.2 , pp. 390-399
    • Lastro, M.1    Kourtidis, A.2    Farley, K.3    Conklin, D.S.4
  • 102
    • 77955057718 scopus 로고    scopus 로고
    • NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: Contributions to pHi regulation and chemotherapy resistance
    • G. Lauritzen, M.B. Jensen, E. Boedtkjer, R. Dybboe, C. Aalkjaer, J. Nylandsted, and S.F. Pedersen NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance Exp. Cell. Res. 316 15 2010 2538 2553
    • (2010) Exp. Cell. Res. , vol.316 , Issue.15 , pp. 2538-2553
    • Lauritzen, G.1    Jensen, M.B.2    Boedtkjer, E.3    Dybboe, R.4    Aalkjaer, C.5    Nylandsted, J.6    Pedersen, S.F.7
  • 105
    • 0033990196 scopus 로고    scopus 로고
    • Changes of glucose transporters in the cerebral adaptation to hypoglycemia
    • D.H. Lee, M.Y. Chung, J.U. Lee, D.G. Kang, and Y.W. Paek Changes of glucose transporters in the cerebral adaptation to hypoglycemia Diabetes Res. Clin. Pract. 47 1 2000 15 23
    • (2000) Diabetes Res. Clin. Pract. , vol.47 , Issue.1 , pp. 15-23
    • Lee, D.H.1    Chung, M.Y.2    Lee, J.U.3    Kang, D.G.4    Paek, Y.W.5
  • 107
    • 79960103892 scopus 로고    scopus 로고
    • NHE1 mediates MDA-MB-231 cells invasion through the regulation of MT1-MMP
    • Y. Lin, G. Chang, J. Wang, W. Jin, L. Wang, H. Li, L. Ma, Q. Li, and T. Pang NHE1 mediates MDA-MB-231 cells invasion through the regulation of MT1-MMP Exp. Cell. Res. 317 14 2011 2031 2040
    • (2011) Exp. Cell. Res. , vol.317 , Issue.14 , pp. 2031-2040
    • Lin, Y.1    Chang, G.2    Wang, J.3    Jin, W.4    Wang, L.5    Li, H.6    Ma, L.7    Li, Q.8    Pang, T.9
  • 108
    • 0012595471 scopus 로고    scopus 로고
    • Down-regulation of thiamine transporter THTR2 gene expression in breast cancer and its association with resistance to apoptosis
    • S. Liu, H. Huang, X. Lu, M. Golinski, S. Comesse, D. Watt, R.B. Grossman, and J.A. Moscow Down-regulation of thiamine transporter THTR2 gene expression in breast cancer and its association with resistance to apoptosis Mol. Cancer Res. 1 9 2003 665 673
    • (2003) Mol. Cancer Res. , vol.1 , Issue.9 , pp. 665-673
    • Liu, S.1    Huang, H.2    Lu, X.3    Golinski, M.4    Comesse, S.5    Watt, D.6    Grossman, R.B.7    Moscow, J.A.8
  • 109
    • 3042701853 scopus 로고    scopus 로고
    • Platelet-derived growth factor stimulates LAT1 gene expression in vascular smooth muscle: Role in cell growth
    • X.M. Liu, S.V. Reyna, D. Ensenat, K.J. Peyton, H. Wang, A.I. Schafer, and W. Durante Platelet-derived growth factor stimulates LAT1 gene expression in vascular smooth muscle: role in cell growth FASEB J. 18 6 2004 768 770
    • (2004) FASEB J. , vol.18 , Issue.6 , pp. 768-770
    • Liu, X.M.1    Reyna, S.V.2    Ensenat, D.3    Peyton, K.J.4    Wang, H.5    Schafer, A.I.6    Durante, W.7
  • 112
    • 25644446715 scopus 로고    scopus 로고
    • Interferon-gamma-induced STAT1-mediated membrane retention of NHE1 and associated proteins ezrin, radixin and moesin in HT-29 cells
    • F. Magro, S. Fraga, and P. Soares-da-Silva Interferon-gamma-induced STAT1-mediated membrane retention of NHE1 and associated proteins ezrin, radixin and moesin in HT-29 cells Biochem. Pharmacol. 70 9 2005 1312 1319
    • (2005) Biochem. Pharmacol. , vol.70 , Issue.9 , pp. 1312-1319
    • Magro, F.1    Fraga, S.2    Soares-Da-Silva, P.3
  • 113
    • 77957903556 scopus 로고    scopus 로고
    • Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1
    • K. Mandery, K. Bujok, I. Schmidt, M. Keiser, W. Siegmund, B. Balk, J. Konig, M.F. Fromm, and H. Glaeser Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1 Biochem. Pharmacol. 80 11 2010 1746 1753
    • (2010) Biochem. Pharmacol. , vol.80 , Issue.11 , pp. 1746-1753
    • Mandery, K.1    Bujok, K.2    Schmidt, I.3    Keiser, M.4    Siegmund, W.5    Balk, B.6    Konig, J.7    Fromm, M.F.8    Glaeser, H.9
  • 114
    • 0023723087 scopus 로고
    • Effects of oestrogen on the expression of a 4.4 kb mRNA in the ZR-75-1 human breast cancer cell line
    • D.L. Manning, R.J. Daly, P.G. Lord, K.F. Kelly, and C.D. Green Effects of oestrogen on the expression of a 4.4 kb mRNA in the ZR-75-1 human breast cancer cell line Mol. Cell Endocrinol. 59 3 1988 205 212
    • (1988) Mol. Cell Endocrinol. , vol.59 , Issue.3 , pp. 205-212
    • Manning, D.L.1    Daly, R.J.2    Lord, P.G.3    Kelly, K.F.4    Green, C.D.5
  • 116
    • 4644226877 scopus 로고    scopus 로고
    • Stem cell factor and H2O2 induce GLUT1 translocation in M07e cells
    • T. Maraldi, D. Fiorentini, C. Prata, L. Landi, and G. Hakim Stem cell factor and H2O2 induce GLUT1 translocation in M07e cells Biofactors 20 2 2004 97 108
    • (2004) Biofactors , vol.20 , Issue.2 , pp. 97-108
    • Maraldi, T.1    Fiorentini, D.2    Prata, C.3    Landi, L.4    Hakim, G.5
  • 117
    • 0031022499 scopus 로고    scopus 로고
    • Effect of glucose transport inhibitors on vincristine efflux in multidrug-resistant murine erythroleukaemia cells overexpressing the multidrug resistance-associated protein (MRP) and two glucose transport proteins, GLUT1 and GLUT3
    • R.L. Martell, C.A. Slapak, and S.B. Levy Effect of glucose transport inhibitors on vincristine efflux in multidrug-resistant murine erythroleukaemia cells overexpressing the multidrug resistance-associated protein (MRP) and two glucose transport proteins, GLUT1 and GLUT3 Br. J. Cancer 75 2 1997 161 168
    • (1997) Br. J. Cancer , vol.75 , Issue.2 , pp. 161-168
    • Martell, R.L.1    Slapak, C.A.2    Levy, S.B.3
  • 120
    • 43449133278 scopus 로고    scopus 로고
    • Resistance to chemotherapy in cancer: A complex and integrated cellular response
    • H.R. Mellor, and R. Callaghan Resistance to chemotherapy in cancer: a complex and integrated cellular response Pharmacology 81 4 2008 275 300
    • (2008) Pharmacology , vol.81 , Issue.4 , pp. 275-300
    • Mellor, H.R.1    Callaghan, R.2
  • 121
    • 0034730622 scopus 로고    scopus 로고
    • Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4
    • A. Mercado, L. Song, N. Vazquez, D.B. Mount, and G. Gamba Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4 J. Biol. Chem. 275 39 2000 30326 30334
    • (2000) J. Biol. Chem. , vol.275 , Issue.39 , pp. 30326-30334
    • Mercado, A.1    Song, L.2    Vazquez, N.3    Mount, D.B.4    Gamba, G.5
  • 124
    • 75649088164 scopus 로고    scopus 로고
    • Ras responsive element binding protein-1 (RREB-1) down-regulates hZIP1 expression in prostate cancer cells
    • B.C. Milon, A. Agyapong, R. Bautista, L.C. Costello, and R.B. Franklin Ras responsive element binding protein-1 (RREB-1) down-regulates hZIP1 expression in prostate cancer cells Prostate 70 3 2010 288 296
    • (2010) Prostate , vol.70 , Issue.3 , pp. 288-296
    • Milon, B.C.1    Agyapong, A.2    Bautista, R.3    Costello, L.C.4    Franklin, R.B.5
  • 127
    • 68049109460 scopus 로고    scopus 로고
    • The calcineurin inhibitor FK506 (tacrolimus) is associated with transient metabolic acidosis and altered expression of renal acid-base transport proteins
    • N. Mohebbi, M. Mihailova, and C.A. Wagner The calcineurin inhibitor FK506 (tacrolimus) is associated with transient metabolic acidosis and altered expression of renal acid-base transport proteins Am. J. Physiol. Renal Physiol. 297 2 2009 F499 F509
    • (2009) Am. J. Physiol. Renal Physiol. , vol.297 , Issue.2
    • Mohebbi, N.1    Mihailova, M.2    Wagner, C.A.3
  • 128
    • 77956288767 scopus 로고    scopus 로고
    • Loss of PTEN binding adapter protein NHERF1 from plasma membrane in glioblastoma contributes to PTEN inactivation
    • J.R. Molina, F.C. Morales, Y. Hayashi, K.D. Aldape, and M.M. Georgescu Loss of PTEN binding adapter protein NHERF1 from plasma membrane in glioblastoma contributes to PTEN inactivation Cancer Res. 70 17 2010 6697 6703
    • (2010) Cancer Res. , vol.70 , Issue.17 , pp. 6697-6703
    • Molina, J.R.1    Morales, F.C.2    Hayashi, Y.3    Aldape, K.D.4    Georgescu, M.M.5
  • 129
    • 79960140546 scopus 로고    scopus 로고
    • Solute carrier transporters as targets for drug delivery and pharmacological intervention for chemotherapy
    • T. Nakanishi, and I. Tamai Solute carrier transporters as targets for drug delivery and pharmacological intervention for chemotherapy J. Pharm. Sci. 100 9 2011 3731 3750
    • (2011) J. Pharm. Sci. , vol.100 , Issue.9 , pp. 3731-3750
    • Nakanishi, T.1    Tamai, I.2
  • 131
    • 60549113316 scopus 로고    scopus 로고
    • Reduced phosphorylation of AS160 contributes to glucocorticoid-mediated inhibition of glucose uptake in human and murine adipocytes
    • S. Ngo, J.B. Barry, J.C. Nisbet, J.B. Prins, and J.P. Whitehead Reduced phosphorylation of AS160 contributes to glucocorticoid-mediated inhibition of glucose uptake in human and murine adipocytes Mol. Cell Endocrinol. 302 1 2009 33 40
    • (2009) Mol. Cell Endocrinol. , vol.302 , Issue.1 , pp. 33-40
    • Ngo, S.1    Barry, J.B.2    Nisbet, J.C.3    Prins, J.B.4    Whitehead, J.P.5
  • 133
    • 79960295006 scopus 로고    scopus 로고
    • Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs)
    • A.T. Nies, U. Hofmann, C. Resch, E. Schaeffeler, M. Rius, and M. Schwab Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs) PLoS One 6 7 2011 e22163
    • (2011) PLoS One , vol.6 , Issue.7 , pp. 22163
    • Nies, A.T.1    Hofmann, U.2    Resch, C.3    Schaeffeler, E.4    Rius, M.5    Schwab, M.6
  • 134
    • 0035884416 scopus 로고    scopus 로고
    • Molecular events involved in up-regulating human Na+-independent neutral amino acid transporter LAT1 during T-cell activation
    • T. Nii, H. Segawa, Y. Taketani, Y. Tani, M. Ohkido, S. Kishida, M. Ito, H. Endou, Y. Kanai, E. Takeda, and K. Miyamoto Molecular events involved in up-regulating human Na+-independent neutral amino acid transporter LAT1 during T-cell activation Biochem. J. 358 Pt 3 2001 693 704
    • (2001) Biochem. J. , vol.358 , Issue.PART 3 , pp. 693-704
    • Nii, T.1    Segawa, H.2    Taketani, Y.3    Tani, Y.4    Ohkido, M.5    Kishida, S.6    Ito, M.7    Endou, H.8    Kanai, Y.9    Takeda, E.10    Miyamoto, K.11
  • 135
    • 78649849854 scopus 로고    scopus 로고
    • Cisplatin upregulates glutamine transport in human intestinal epithelial cells: The protective mechanism of glutamine on intestinal mucosa after chemotherapy
    • S. Nose, M. Wasa, Y. Tazuke, M. Owari, and M. Fukuzawa Cisplatin upregulates glutamine transport in human intestinal epithelial cells: the protective mechanism of glutamine on intestinal mucosa after chemotherapy JPEN J. Parenter. Enteral Nutr. 34 5 2010 530 537
    • (2010) JPEN J. Parenter. Enteral Nutr. , vol.34 , Issue.5 , pp. 530-537
    • Nose, S.1    Wasa, M.2    Tazuke, Y.3    Owari, M.4    Fukuzawa, M.5
  • 137
    • 33744924881 scopus 로고    scopus 로고
    • Functional expression of A glutamine transporter responsive to down-regulation by lipopolysaccharide through reduced promoter activity in cultured rat neocortical astrocytes
    • M. Ogura, N. Nakamichi, K. Takano, H. Oikawa, Y. Kambe, Y. Ohno, H. Taniura, and Y. Yoneda Functional expression of A glutamine transporter responsive to down-regulation by lipopolysaccharide through reduced promoter activity in cultured rat neocortical astrocytes J. Neurosci. Res. 83 8 2006 1447 1460
    • (2006) J. Neurosci. Res. , vol.83 , Issue.8 , pp. 1447-1460
    • Ogura, M.1    Nakamichi, N.2    Takano, K.3    Oikawa, H.4    Kambe, Y.5    Ohno, Y.6    Taniura, H.7    Yoneda, Y.8
  • 138
    • 34249996281 scopus 로고    scopus 로고
    • Correlation of induction of ATP binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor
    • S. Ohtsuki, M. Kamoi, Y. Watanabe, H. Suzuki, S. Hori, and T. Terasaki Correlation of induction of ATP binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor Biol. Pharm. Bull. 30 6 2007 1144 1146
    • (2007) Biol. Pharm. Bull. , vol.30 , Issue.6 , pp. 1144-1146
    • Ohtsuki, S.1    Kamoi, M.2    Watanabe, Y.3    Suzuki, H.4    Hori, S.5    Terasaki, T.6
  • 140
    • 17644378047 scopus 로고    scopus 로고
    • Role of p53 and reactive oxygen species in apoptotic response to copper and zinc in epithelial breast cancer cells
    • E.A. Ostrakhovitch, and M.G. Cherian Role of p53 and reactive oxygen species in apoptotic response to copper and zinc in epithelial breast cancer cells Apoptosis 10 1 2005 111 121
    • (2005) Apoptosis , vol.10 , Issue.1 , pp. 111-121
    • Ostrakhovitch, E.A.1    Cherian, M.G.2
  • 143
    • 42549172744 scopus 로고    scopus 로고
    • Silencing of the candidate tumor suppressor gene solute carrier family 5 member 8 (SLC5A8) in human pancreatic cancer
    • J.Y. Park, J.F. Helm, W. Zheng, Q.P. Ly, P.J. Hodul, B.A. Centeno, and M.P. Malafa Silencing of the candidate tumor suppressor gene solute carrier family 5 member 8 (SLC5A8) in human pancreatic cancer Pancreas 36 4 2008 e32 e39
    • (2008) Pancreas , vol.36 , Issue.4
    • Park, J.Y.1    Helm, J.F.2    Zheng, W.3    Ly, Q.P.4    Hodul, P.J.5    Centeno, B.A.6    Malafa, M.P.7
  • 144
    • 80054717982 scopus 로고    scopus 로고
    • Hexose transporter GLUT1 harbors several distinct regulatory binding sites for flavones and tyrphostins
    • A. Perez, P. Ojeda, L. Ojeda, M. Salas, C.I. Rivas, J.C. Vera, and A.M. Reyes Hexose transporter GLUT1 harbors several distinct regulatory binding sites for flavones and tyrphostins Biochemistry 50 41 2011 8834 8845
    • (2011) Biochemistry , vol.50 , Issue.41 , pp. 8834-8845
    • Perez, A.1    Ojeda, P.2    Ojeda, L.3    Salas, M.4    Rivas, C.I.5    Vera, J.C.6    Reyes, A.M.7
  • 145
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • K. Polyak, and R.A. Weinberg Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits Nat. Rev. Cancer 9 4 2009 265 273
    • (2009) Nat. Rev. Cancer , vol.9 , Issue.4 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 146
    • 63149194964 scopus 로고    scopus 로고
    • (V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway
    • C.A. Pratilas, B.S. Taylor, Q. Ye, A. Viale, C. Sander, D.B. Solit, and N. Rosen (V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway Proc. Natl. Acad. Sci. USA 106 11 2009 4519 4524
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , Issue.11 , pp. 4519-4524
    • Pratilas, C.A.1    Taylor, B.S.2    Ye, Q.3    Viale, A.4    Sander, C.5    Solit, D.B.6    Rosen, N.7
  • 147
    • 69049088729 scopus 로고    scopus 로고
    • Metabolic effects of blocking lactate transport in brain cortical tissue slices using an inhibitor specific to MCT1 and MCT2
    • C. Rae, F.A. Nasrallah, and S. Broer Metabolic effects of blocking lactate transport in brain cortical tissue slices using an inhibitor specific to MCT1 and MCT2 Neurochem. Res. 34 10 2009 1783 1791
    • (2009) Neurochem. Res. , vol.34 , Issue.10 , pp. 1783-1791
    • Rae, C.1    Nasrallah, F.A.2    Broer, S.3
  • 150
    • 0030839797 scopus 로고    scopus 로고
    • Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid
    • S.C. Rumsey, O. Kwon, G.W. Xu, C.F. Burant, I. Simpson, and M. Levine Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid J. Biol. Chem. 272 30 1997 18982 18989
    • (1997) J. Biol. Chem. , vol.272 , Issue.30 , pp. 18982-18989
    • Rumsey, S.C.1    Kwon, O.2    Xu, G.W.3    Burant, C.F.4    Simpson, I.5    Levine, M.6
  • 151
    • 2142697164 scopus 로고    scopus 로고
    • Neuronal protection from glucose deprivation via modulation of glucose transport and inhibition of apoptosis: A role for the insulin-like growth factor system
    • V.C. Russo, K. Kobayashi, S. Najdovska, N.L. Baker, and G.A. Werther Neuronal protection from glucose deprivation via modulation of glucose transport and inhibition of apoptosis: a role for the insulin-like growth factor system Brain Res. 1009 1-2 2004 40 53
    • (2004) Brain Res. , vol.1009 , Issue.12 , pp. 40-53
    • Russo, V.C.1    Kobayashi, K.2    Najdovska, S.3    Baker, N.L.4    Werther, G.A.5
  • 153
    • 78049408913 scopus 로고    scopus 로고
    • Identification of a novel transport-independent function of PiT1/SLC20A1 in the regulation of TNF-induced apoptosis
    • C. Salaun, C. Leroy, A. Rousseau, V. Boitez, L. Beck, and G. Friedlander Identification of a novel transport-independent function of PiT1/SLC20A1 in the regulation of TNF-induced apoptosis J. Biol. Chem. 285 45 2010 34408 34418
    • (2010) J. Biol. Chem. , vol.285 , Issue.45 , pp. 34408-34418
    • Salaun, C.1    Leroy, C.2    Rousseau, A.3    Boitez, V.4    Beck, L.5    Friedlander, G.6
  • 154
    • 78650014696 scopus 로고    scopus 로고
    • Regulation of amino acid/carnitine transporter B 0,+ (ATB 0,+) in astrocytes by protein kinase C: Independent effects on raft and non-raft transporter subpopulations
    • L. Samluk, M. Czeredys, and K.A. Nalecz Regulation of amino acid/carnitine transporter B 0,+ (ATB 0,+) in astrocytes by protein kinase C: independent effects on raft and non-raft transporter subpopulations J. Neurochem. 115 6 2010 1386 1397
    • (2010) J. Neurochem. , vol.115 , Issue.6 , pp. 1386-1397
    • Samluk, L.1    Czeredys, M.2    Nalecz, K.A.3
  • 155
    • 2042489653 scopus 로고    scopus 로고
    • Endothelin-1 stimulates the translocation and upregulation of both glucose transporter and hexokinase in astrocytes: Relationship with gap junctional communication
    • R. Sanchez-Alvarez, A. Tabernero, and J.M. Medina Endothelin-1 stimulates the translocation and upregulation of both glucose transporter and hexokinase in astrocytes: relationship with gap junctional communication J. Neurochem. 89 3 2004 703 714
    • (2004) J. Neurochem. , vol.89 , Issue.3 , pp. 703-714
    • Sanchez-Alvarez, R.1    Tabernero, A.2    Medina, J.M.3
  • 156
    • 0032742374 scopus 로고    scopus 로고
    • Expression of E16/CD98LC/hLAT1 is responsive to 2,3,7,8- tetrachlorodibenzo-p-dioxin
    • D. Sarkar, F. Kambe, A. Hirata, A. Iseki, S. Ohmori, and H. Seo Expression of E16/CD98LC/hLAT1 is responsive to 2,3,7,8-tetrachlorodibenzo-p- dioxin FEBS Lett. 462 3 1999 430 434
    • (1999) FEBS Lett. , vol.462 , Issue.3 , pp. 430-434
    • Sarkar, D.1    Kambe, F.2    Hirata, A.3    Iseki, A.4    Ohmori, S.5    Seo, H.6
  • 158
    • 0027252639 scopus 로고
    • Identification of a colon mucosa gene that is down-regulated in colon adenomas and adenocarcinomas
    • C.W. Schweinfest, K.W. Henderson, S. Suster, N. Kondoh, and T.S. Papas Identification of a colon mucosa gene that is down-regulated in colon adenomas and adenocarcinomas Proc. Natl. Acad. Sci. USA 90 9 1993 4166 4170
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , Issue.9 , pp. 4166-4170
    • Schweinfest, C.W.1    Henderson, K.W.2    Suster, S.3    Kondoh, N.4    Papas, T.S.5
  • 159
    • 33750561865 scopus 로고    scopus 로고
    • Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively
    • I.G. Shabalina, T.V. Kramarova, J. Nedergaard, and B. Cannon Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively Biochem. J. 399 3 2006 405 414
    • (2006) Biochem. J. , vol.399 , Issue.3 , pp. 405-414
    • Shabalina, I.G.1    Kramarova, T.V.2    Nedergaard, J.3    Cannon, B.4
  • 160
    • 0034277056 scopus 로고    scopus 로고
    • Volume-sensitive KCI cotransport associated with human cervical carcinogenesis
    • M.R. Shen, C.Y. Chou, and J.C. Ellory Volume-sensitive KCI cotransport associated with human cervical carcinogenesis Pflugers Arch. 440 5 2000 751 760
    • (2000) Pflugers Arch. , vol.440 , Issue.5 , pp. 751-760
    • Shen, M.R.1    Chou, C.Y.2    Ellory, J.C.3
  • 161
    • 4544384011 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells
    • M.R. Shen, A.C. Lin, Y.M. Hsu, T.J. Chang, M.J. Tang, S.L. Alper, J.C. Ellory, and C.Y. Chou Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells J. Biol. Chem. 279 38 2004 40017 40025
    • (2004) J. Biol. Chem. , vol.279 , Issue.38 , pp. 40017-40025
    • Shen, M.R.1    Lin, A.C.2    Hsu, Y.M.3    Chang, T.J.4    Tang, M.J.5    Alper, S.L.6    Ellory, J.C.7    Chou, C.Y.8
  • 162
    • 55249114168 scopus 로고    scopus 로고
    • Inhibition of system L (LAT1/CD98hc) reduces the growth of cultured human breast cancer cells
    • D.B. Shennan, and J. Thomson Inhibition of system L (LAT1/CD98hc) reduces the growth of cultured human breast cancer cells Oncol. Rep. 20 4 2008 885 889
    • (2008) Oncol. Rep. , vol.20 , Issue.4 , pp. 885-889
    • Shennan, D.B.1    Thomson, J.2
  • 163
    • 80052647286 scopus 로고    scopus 로고
    • Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains
    • Y. Shi, V. Chanana, J.J. Watters, P. Ferrazzano, and D. Sun Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains J. Neurochem. 119 1 2011 124 135
    • (2011) J. Neurochem. , vol.119 , Issue.1 , pp. 124-135
    • Shi, Y.1    Chanana, V.2    Watters, J.J.3    Ferrazzano, P.4    Sun, D.5
  • 164
    • 60549103094 scopus 로고    scopus 로고
    • Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine
    • V. Shnitsar, R. Eckardt, S. Gupta, J. Grottker, G.A. Muller, H. Koepsell, G. Burckhardt, and Y. Hagos Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine Cancer Res. 69 4 2009 1494 1501
    • (2009) Cancer Res. , vol.69 , Issue.4 , pp. 1494-1501
    • Shnitsar, V.1    Eckardt, R.2    Gupta, S.3    Grottker, J.4    Muller, G.A.5    Koepsell, H.6    Burckhardt, G.7    Hagos, Y.8
  • 166
    • 82655176963 scopus 로고    scopus 로고
    • IKKbeta and NF-kappaB Transcription Govern Lymphoma Cell Survival through AKT-Induced Plasma Membrane Trafficking of GLUT1
    • T.G. Sommermann, K. O'Neill, D.R. Plas, and E. Cahir-McFarland IKKbeta and NF-kappaB Transcription Govern Lymphoma Cell Survival through AKT-Induced Plasma Membrane Trafficking of GLUT1 Cancer Res. 71 2011 7291 7300
    • (2011) Cancer Res. , vol.71 , pp. 7291-7300
    • Sommermann, T.G.1    O'Neill, K.2    Plas, D.R.3    Cahir-Mcfarland, E.4
  • 167
    • 51249094302 scopus 로고    scopus 로고
    • Astrocytic alkalinization by therapeutically relevant lithium concentrations: Implications for myo-inositol depletion
    • D. Song, T. Du, B. Li, L. Cai, L. Gu, H. Li, Y. Chen, L. Hertz, and L. Peng Astrocytic alkalinization by therapeutically relevant lithium concentrations: implications for myo-inositol depletion Psychopharmacology (Berl) 200 2 2008 187 195
    • (2008) Psychopharmacology (Berl) , vol.200 , Issue.2 , pp. 187-195
    • Song, D.1    Du, T.2    Li, B.3    Cai, L.4    Gu, L.5    Li, H.6    Chen, Y.7    Hertz, L.8    Peng, L.9
  • 169
    • 0029870954 scopus 로고    scopus 로고
    • The war on cancer
    • M.B. Sporn The war on cancer Lancet 347 9012 1996 1377 1381
    • (1996) Lancet , vol.347 , Issue.9012 , pp. 1377-1381
    • Sporn, M.B.1
  • 170
    • 77957332150 scopus 로고    scopus 로고
    • Deficiency of electroneutral K+-Cl- cotransporter 3 causes a disruption in impulse propagation along peripheral nerves
    • Y.T. Sun, T.S. Lin, S.F. Tzeng, E. Delpire, and M.R. Shen Deficiency of electroneutral K+-Cl- cotransporter 3 causes a disruption in impulse propagation along peripheral nerves Glia 58 13 2010 1544 1552
    • (2010) Glia , vol.58 , Issue.13 , pp. 1544-1552
    • Sun, Y.T.1    Lin, T.S.2    Tzeng, S.F.3    Delpire, E.4    Shen, M.R.5
  • 171
    • 0142009677 scopus 로고    scopus 로고
    • Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters
    • K.M. Taylor, H.E. Morgan, A. Johnson, L.J. Hadley, and R.I. Nicholson Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters Biochem. J. 375 Pt 1 2003 51 59
    • (2003) Biochem. J. , vol.375 , Issue.PART 1 , pp. 51-59
    • Taylor, K.M.1    Morgan, H.E.2    Johnson, A.3    Hadley, L.J.4    Nicholson, R.I.5
  • 173
    • 70350101307 scopus 로고    scopus 로고
    • Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate
    • M. Thangaraju, S.K. Karunakaran, S. Itagaki, E. Gopal, S. Elangovan, P.D. Prasad, and V. Ganapathy Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate Cancer 115 20 2009 4655 4666
    • (2009) Cancer , vol.115 , Issue.20 , pp. 4655-4666
    • Thangaraju, M.1    Karunakaran, S.K.2    Itagaki, S.3    Gopal, E.4    Elangovan, S.5    Prasad, P.D.6    Ganapathy, V.7
  • 174
    • 55249112985 scopus 로고    scopus 로고
    • Activated transcription via mammalian amino acid response elements does not require enhanced recruitment of the Mediator complex
    • M.M. Thiaville, E.E. Dudenhausen, K.S. Awad, A. Gjymishka, C. Zhong, and M.S. Kilberg Activated transcription via mammalian amino acid response elements does not require enhanced recruitment of the Mediator complex Nucleic Acids Res. 36 17 2008 5571 5580
    • (2008) Nucleic Acids Res. , vol.36 , Issue.17 , pp. 5571-5580
    • Thiaville, M.M.1    Dudenhausen, E.E.2    Awad, K.S.3    Gjymishka, A.4    Zhong, C.5    Kilberg, M.S.6
  • 176
    • 79953802503 scopus 로고    scopus 로고
    • Tamoxifen and raloxifene suppress the proliferation of estrogen receptor-negative cells through inhibition of glutamine uptake
    • V.K. Todorova, Y. Kaufmann, S. Luo, and V.S. Klimberg Tamoxifen and raloxifene suppress the proliferation of estrogen receptor-negative cells through inhibition of glutamine uptake Cancer Chemother. Pharmacol. 67 2 2011 285 291
    • (2011) Cancer Chemother. Pharmacol. , vol.67 , Issue.2 , pp. 285-291
    • Todorova, V.K.1    Kaufmann, Y.2    Luo, S.3    Klimberg, V.S.4
  • 177
    • 34548544377 scopus 로고    scopus 로고
    • Expression of glucose transporters in epithelial ovarian carcinoma: Correlation with clinical characteristics and tumor angiogenesis
    • M. Tsukioka, Y. Matsumoto, M. Noriyuki, C. Yoshida, H. Nobeyama, H. Yoshida, T. Yasui, T. Sumi, K. Honda, and O. Ishiko Expression of glucose transporters in epithelial ovarian carcinoma: correlation with clinical characteristics and tumor angiogenesis Oncol. Rep. 18 2 2007 361 367
    • (2007) Oncol. Rep. , vol.18 , Issue.2 , pp. 361-367
    • Tsukioka, M.1    Matsumoto, Y.2    Noriyuki, M.3    Yoshida, C.4    Nobeyama, H.5    Yoshida, H.6    Yasui, T.7    Sumi, T.8    Honda, K.9    Ishiko, O.10
  • 178
    • 34447302853 scopus 로고    scopus 로고
    • Hyperglycemia regulates thioredoxin-ROS activity through induction of thioredoxin-interacting protein (TXNIP) in metastatic breast cancer-derived cells MDA-MB-231
    • F. Turturro, E. Friday, and T. Welbourne Hyperglycemia regulates thioredoxin-ROS activity through induction of thioredoxin-interacting protein (TXNIP) in metastatic breast cancer-derived cells MDA-MB-231 BMC Cancer 7 2007 96
    • (2007) BMC Cancer , vol.7 , pp. 96
    • Turturro, F.1    Friday, E.2    Welbourne, T.3
  • 179
    • 17644390584 scopus 로고    scopus 로고
    • Functional regulation of Na+-dependent neutral amino acid transporter ASCT2 by S-nitrosothiols and nitric oxide in Caco-2 cells
    • T. Uchiyama, Y. Matsuda, M. Wada, S. Takahashi, and T. Fujita Functional regulation of Na+-dependent neutral amino acid transporter ASCT2 by S-nitrosothiols and nitric oxide in Caco-2 cells FEBS Lett. 579 11 2005 2499 2506
    • (2005) FEBS Lett. , vol.579 , Issue.11 , pp. 2499-2506
    • Uchiyama, T.1    Matsuda, Y.2    Wada, M.3    Takahashi, S.4    Fujita, T.5
  • 180
    • 0036299010 scopus 로고    scopus 로고
    • Selective up-regulation of system a transporter mRNA in diabetic liver
    • H. Varoqui, and J.D. Erickson Selective up-regulation of system a transporter mRNA in diabetic liver Biochem. Biophys. Res. Commun. 290 3 2002 903 908
    • (2002) Biochem. Biophys. Res. Commun. , vol.290 , Issue.3 , pp. 903-908
    • Varoqui, H.1    Erickson, J.D.2
  • 181
    • 0025763309 scopus 로고
    • A possible role for a mammalian facilitative hexose transporter in the development of resistance to drugs
    • J.C. Vera, G.R. Castillo, and O.M. Rosen A possible role for a mammalian facilitative hexose transporter in the development of resistance to drugs Mol. Cell Biol. 11 7 1991 3407 3418
    • (1991) Mol. Cell Biol. , vol.11 , Issue.7 , pp. 3407-3418
    • Vera, J.C.1    Castillo, G.R.2    Rosen, O.M.3
  • 184
    • 33947200585 scopus 로고    scopus 로고
    • Vacuolar H+-ATPase expression is increased in acid-secreting intercalated cells in kidneys of rats with hypercalcaemia-induced alkalosis
    • W. Wang, J. Praetorius, C. Li, H.A. Praetorius, T.H. Kwon, J. Frokiaer, and S. Nielsen Vacuolar H+-ATPase expression is increased in acid-secreting intercalated cells in kidneys of rats with hypercalcaemia-induced alkalosis Acta Physiol. (Oxf) 189 4 2007 359 368
    • (2007) Acta Physiol. (Oxf) , vol.189 , Issue.4 , pp. 359-368
    • Wang, W.1    Praetorius, J.2    Li, C.3    Praetorius, H.A.4    Kwon, T.H.5    Frokiaer, J.6    Nielsen, S.7
  • 185
    • 65749104457 scopus 로고    scopus 로고
    • Inhibition of hypoxia inducible factor by phenethyl isothiocyanate
    • X.H. Wang, B.E. Cavell, S.S. Syed Alwi, and G. Packham Inhibition of hypoxia inducible factor by phenethyl isothiocyanate Biochem. Pharmacol. 78 3 2009 261 272
    • (2009) Biochem. Pharmacol. , vol.78 , Issue.3 , pp. 261-272
    • Wang, X.H.1    Cavell, B.E.2    Syed Alwi, S.S.3    Packham, G.4
  • 188
    • 78649644992 scopus 로고    scopus 로고
    • DNA damage-induced modulation of GLUT3 expression is mediated through p53-independent extracellular signal-regulated kinase signaling in HeLa cells
    • M. Watanabe, H. Naraba, T. Sakyo, and T. Kitagawa DNA damage-induced modulation of GLUT3 expression is mediated through p53-independent extracellular signal-regulated kinase signaling in HeLa cells Mol. Cancer Res. 8 11 2010 1547 1557
    • (2010) Mol. Cancer Res. , vol.8 , Issue.11 , pp. 1547-1557
    • Watanabe, M.1    Naraba, H.2    Sakyo, T.3    Kitagawa, T.4
  • 189
  • 190
    • 42949176742 scopus 로고    scopus 로고
    • Survival of cancer cells is maintained by EGFR independent of its kinase activity
    • Z. Weihua, R. Tsan, W.C. Huang, Q. Wu, C.H. Chiu, I.J. Fidler, and M.C. Hung Survival of cancer cells is maintained by EGFR independent of its kinase activity Cancer Cell 13 5 2008 385 393
    • (2008) Cancer Cell , vol.13 , Issue.5 , pp. 385-393
    • Weihua, Z.1    Tsan, R.2    Huang, W.C.3    Wu, Q.4    Chiu, C.H.5    Fidler, I.J.6    Hung, M.C.7
  • 192
    • 63849189798 scopus 로고    scopus 로고
    • Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons
    • P. Weisova, C.G. Concannon, M. Devocelle, J.H. Prehn, and M.W. Ward Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons J. Neurosci. 29 9 2009 2997 3008
    • (2009) J. Neurosci. , vol.29 , Issue.9 , pp. 2997-3008
    • Weisova, P.1    Concannon, C.G.2    Devocelle, M.3    Prehn, J.H.4    Ward, M.W.5
  • 193
    • 79954447258 scopus 로고    scopus 로고
    • Oxybutynin and trospium are substrates of the human organic cation transporters
    • B. Wenge, J. Geyer, and H. Bonisch Oxybutynin and trospium are substrates of the human organic cation transporters Naunyn Schmiedebergs Arch. Pharmacol. 383 2 2011 203 208
    • (2011) Naunyn Schmiedebergs Arch. Pharmacol. , vol.383 , Issue.2 , pp. 203-208
    • Wenge, B.1    Geyer, J.2    Bonisch, H.3
  • 194
    • 33748548397 scopus 로고    scopus 로고
    • Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptake
    • H.A. Wetli, P.D. Buckett, and M. Wessling-Resnick Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptake Chem. Biol. 13 9 2006 965 972
    • (2006) Chem. Biol. , vol.13 , Issue.9 , pp. 965-972
    • Wetli, H.A.1    Buckett, P.D.2    Wessling-Resnick, M.3
  • 196
    • 5144235557 scopus 로고    scopus 로고
    • Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction
    • D.E. White, N.A. Kurpios, D. Zuo, J.A. Hassell, S. Blaess, U. Mueller, and W.J. Muller Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction Cancer Cell 6 2 2004 159 170
    • (2004) Cancer Cell , vol.6 , Issue.2 , pp. 159-170
    • White, D.E.1    Kurpios, N.A.2    Zuo, D.3    Hassell, J.A.4    Blaess, S.5    Mueller, U.6    Muller, W.J.7
  • 197
    • 0037263730 scopus 로고    scopus 로고
    • Epidermal growth factor activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases
    • C.L. Wolfgang, C. Lin, Q. Meng, A.M. Karinch, T.C. Vary, and M. Pan Epidermal growth factor activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases J. Gastrointest. Surg. 7 1 2003 149 156
    • (2003) J. Gastrointest. Surg. , vol.7 , Issue.1 , pp. 149-156
    • Wolfgang, C.L.1    Lin, C.2    Meng, Q.3    Karinch, A.M.4    Vary, T.C.5    Pan, M.6
  • 198
    • 76649096671 scopus 로고    scopus 로고
    • Differential effects of 5-fluorouracil on glucose transport and expressions of glucose transporter proteins in gastric cancer cells
    • H.J. Won, T.K. Ha, S.J. Kwon, H.Y. Cho, S.J. Hur, H.H. Baik, S.I. Suh, E. Ha, and Y.H. Kim Differential effects of 5-fluorouracil on glucose transport and expressions of glucose transporter proteins in gastric cancer cells Anticancer Drugs 21 3 2010 270 276
    • (2010) Anticancer Drugs , vol.21 , Issue.3 , pp. 270-276
    • Won, H.J.1    Ha, T.K.2    Kwon, S.J.3    Cho, H.Y.4    Hur, S.J.5    Baik, H.H.6    Suh, S.I.7    Ha, E.8    Kim, Y.H.9
  • 202
    • 2442674220 scopus 로고    scopus 로고
    • Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer
    • S. Yamashita, C. Miyagi, T. Fukada, N. Kagara, Y.S. Che, and T. Hirano Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer Nature 429 6989 2004 298 302
    • (2004) Nature , vol.429 , Issue.6989 , pp. 298-302
    • Yamashita, S.1    Miyagi, C.2    Fukada, T.3    Kagara, N.4    Che, Y.S.5    Hirano, T.6
  • 203
    • 78851469003 scopus 로고    scopus 로고
    • Expression and modulation of Na(+) /H(+) exchanger 1 gene in hepatocellular carcinoma: A potential therapeutic target
    • X. Yang, D. Wang, W. Dong, Z. Song, and K. Dou Expression and modulation of Na(+) /H(+) exchanger 1 gene in hepatocellular carcinoma: a potential therapeutic target J. Gastroenterol. Hepatol. 26 2 2011 364 370
    • (2011) J. Gastroenterol. Hepatol. , vol.26 , Issue.2 , pp. 364-370
    • Yang, X.1    Wang, D.2    Dong, W.3    Song, Z.4    Dou, K.5
  • 204
    • 79952244214 scopus 로고    scopus 로고
    • Suppression of Na+/H + exchanger 1 by RNA interference or amiloride inhibits human hepatoma cell line SMMC-7721 cell invasion
    • X. Yang, D. Wang, W. Dong, Z. Song, and K. Dou Suppression of Na+/H + exchanger 1 by RNA interference or amiloride inhibits human hepatoma cell line SMMC-7721 cell invasion Med. Oncol. 28 1 2011 385 390
    • (2011) Med. Oncol. , vol.28 , Issue.1 , pp. 385-390
    • Yang, X.1    Wang, D.2    Dong, W.3    Song, Z.4    Dou, K.5
  • 206
    • 0036636782 scopus 로고    scopus 로고
    • Effect of co-inhibition of MCT1 gene and NHE1 gene on proliferation and growth of human lung adenocarcinoma cells
    • G.Z. Zhang, G.J. Huang, W.L. Li, G.M. Wu, and G.S. Qian Effect of co-inhibition of MCT1 gene and NHE1 gene on proliferation and growth of human lung adenocarcinoma cells Ai Zheng 21 7 2002 719 723
    • (2002) Ai Zheng , vol.21 , Issue.7 , pp. 719-723
    • Zhang, G.Z.1    Huang, G.J.2    Li, W.L.3    Wu, G.M.4    Qian, G.S.5
  • 207
    • 34247538936 scopus 로고    scopus 로고
    • DNA methylation dependent silencing of the human glutamate transporter EAAT2 gene in glial cells
    • J. Zschocke, C. Allritz, J. Engele, and T. Rein DNA methylation dependent silencing of the human glutamate transporter EAAT2 gene in glial cells Glia 55 7 2007 663 674
    • (2007) Glia , vol.55 , Issue.7 , pp. 663-674
    • Zschocke, J.1    Allritz, C.2    Engele, J.3    Rein, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.