-
1
-
-
17144398831
-
Possible future issues in the treatment of glioblastomas: Special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis
-
DOI 10.1200/JCO.2005.03.089
-
Lefranc F, Brotchi J, Kiss R. Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. J Clin Oncol 2005;23: 2411-22. (Pubitemid 46218735)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.10
, pp. 2411-2422
-
-
Lefranc, F.1
Brotchi, J.2
Kiss, R.3
-
2
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
DOI 10.1074/jbc.273.22.13375
-
Maehama T, Dixon JE. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 1998;273:13375-8. (Pubitemid 28268370)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.22
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
3
-
-
54949109808
-
PI3K/Akt: Getting it right matters
-
Franke TF. PI3K/Akt: getting it right matters. Oncogene 2008;27: 6473-88.
-
(2008)
Oncogene
, vol.27
, pp. 6473-6488
-
-
Franke, T.F.1
-
4
-
-
0032518467
-
3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro
-
Alessi DR, Kozlowski MT, Weng QP, Morrice N, Avruch J. 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro. Curr Biol 1998;8: 69-81.
-
(1998)
Curr Biol
, vol.8
, pp. 69-81
-
-
Alessi, D.R.1
Kozlowski, M.T.2
Weng, Q.P.3
Morrice, N.4
Avruch, J.5
-
5
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005;307:1098-101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
6
-
-
0033615538
-
Crystal structure of the PTEN tumor suppressor: Implications for its phosphoinositide phosphatase activity and membrane association
-
Lee JO, Yang H, Georgescu MM, et al. Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell 1999;99:323-34.
-
(1999)
Cell
, vol.99
, pp. 323-334
-
-
Lee, J.O.1
Yang, H.2
Georgescu, M.M.3
-
7
-
-
0033621042
-
The tumor-suppressor activity of PTEN is regulated by its carboxyl- Terminal region
-
DOI 10.1073/pnas.96.18.10182
-
Georgescu MM, Kirsch KH, Akagi T, Shishido T, Hanafusa H. The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region. Proc Natl Acad Sci U S A 1999;96:10182-7. (Pubitemid 29422533)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.18
, pp. 10182-10187
-
-
Georgescu, M.-M.1
Kirsch, K.H.2
Akagi, T.3
Shishido, T.4
Hanafusa, H.5
-
8
-
-
33644504867
-
PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling
-
Takahashi Y, Morales FC, Kreimann EL, Georgescu MM. PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling. EMBO J 2006;25:910-20.
-
(2006)
EMBO J
, vol.25
, pp. 910-920
-
-
Takahashi, Y.1
Morales, F.C.2
Kreimann, E.L.3
Georgescu, M.M.4
-
9
-
-
17744386543
-
Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling
-
von Stein W, Ramrath A, Grimm A, Muller-Borg M, Wodarz A. Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling. Development 2005;132:1675-86.
-
(2005)
Development
, vol.132
, pp. 1675-1686
-
-
Von Stein, W.1
Ramrath, A.2
Grimm, A.3
Muller-Borg, M.4
Wodarz, A.5
-
10
-
-
0034636038
-
Evidence for regulation of the PTEN tumor suppressor by a membrane- Localized multi-PDZ domain containing scaffold protein MAGI-2
-
DOI 10.1073/pnas.97.8.4233
-
Wu X, Hepner K, Castelino-Prabhu S, et al. Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2. Proc Natl Acad Sci U S A 2000;97:4233-8. (Pubitemid 30226116)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.8
, pp. 4233-4238
-
-
Wu, X.1
Hepner, K.2
Castelino-Prabhu, S.3
Do, D.4
Kaye, M.B.5
Yuan, X.-J.6
Wood, J.7
Ross, C.8
Sawyers, C.L.9
Whang, Y.E.10
-
11
-
-
4944255253
-
Genetic pathways to glioblastoma: A population-based study
-
Ohgaki H, Dessen P, Jourde B, et al. Genetic pathways to glioblastoma: a population-based study. Cancer Res 2004;64:6892-9.
-
(2004)
Cancer Res
, vol.64
, pp. 6892-6899
-
-
Ohgaki, H.1
Dessen, P.2
Jourde, B.3
-
12
-
-
4344602002
-
The biology and clinical relevance of the PTEN tumor suppressor pathway
-
Sansal I, Sellers WR. The biology and clinical relevance of the PTEN tumor suppressor pathway. J Clin Oncol 2004;22:2954-63.
-
(2004)
J Clin Oncol
, vol.22
, pp. 2954-2963
-
-
Sansal, I.1
Sellers, W.R.2
-
13
-
-
0032977124
-
Frequent co-alterations of TP53, p16/ CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines
-
Ishii N, Maier D, Merlo A, et al. Frequent co-alterations of TP53, p16/ CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines. Brain Pathol 1999;9:469-79.
-
(1999)
Brain Pathol
, vol.9
, pp. 469-479
-
-
Ishii, N.1
Maier, D.2
Merlo, A.3
-
14
-
-
65549105990
-
NHERF-1: Modulator of glioblastoma cell migration and invasion
-
Kislin KL, McDonough WS, Eschbacher JM, Armstrong BA, Berens ME. NHERF-1: modulator of glioblastoma cell migration and invasion. Neoplasia 2009;11:377-87.
-
(2009)
Neoplasia
, vol.11
, pp. 377-387
-
-
Kislin, K.L.1
McDonough, W.S.2
Eschbacher, J.M.3
Armstrong, B.A.4
Berens, M.E.5
-
15
-
-
77956296330
-
Overexpresssion of ezrin inactivates NF2 tumor suppressor in glioblastoma
-
Morales FC, Molina JR, Hayashi Y, Georgescu MM. Overexpresssion of ezrin inactivates NF2 tumor suppressor in glioblastoma. Neuro Oncol 2010;12:528-39.
-
(2010)
Neuro Oncol
, vol.12
, pp. 528-539
-
-
Morales, F.C.1
Molina, J.R.2
Hayashi, Y.3
Georgescu, M.M.4
-
16
-
-
34547750009
-
Cortical stabilization of β-catenin contributes to NHERF1/EBP50 tumor suppressor function
-
Kreimann EL, Morales FC, de Orbeta-Cruz J, et al. Cortical stabilization of β-catenin contributes to NHERF1/EBP50 tumor suppressor function. Oncogene 2007;26:5290-9.
-
(2007)
Oncogene
, vol.26
, pp. 5290-5299
-
-
Kreimann, E.L.1
Morales, F.C.2
De Orbeta-Cruz, J.3
-
18
-
-
58849102128
-
A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN
-
Rahdar M, Inoue T, Meyer T, Zhang J, Vazquez F, Devreotes PN. A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN. Proc Natl Acad Sci U S A 2009;106:480-5.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 480-485
-
-
Rahdar, M.1
Inoue, T.2
Meyer, T.3
Zhang, J.4
Vazquez, F.5
Devreotes, P.N.6
-
19
-
-
9644255918
-
NHERF (Na+/H+ exchanger regulatory factor) gene mutations in human breast cancer
-
Dai JL, Wang L, Sahin AA, Broemeling LD, Schutte M, Pan Y. NHERF (Na+/H+ exchanger regulatory factor) gene mutations in human breast cancer. Oncogene 2004;23:8681-7.
-
(2004)
Oncogene
, vol.23
, pp. 8681-8687
-
-
Dai, J.L.1
Wang, L.2
Sahin, A.A.3
Broemeling, L.D.4
Schutte, M.5
Pan, Y.6
-
20
-
-
0038121958
-
EBP50, a β-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma
-
DOI 10.1053/jhep.2003.50270
-
Shibata T, Chuma M, Kokubu A, Sakamoto M, Hirohashi S. EBP50, a β-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma. Hepatology 2003;38:178-86. (Pubitemid 36775809)
-
(2003)
Hepatology
, vol.38
, Issue.1
, pp. 178-186
-
-
Shibata, T.1
Chuma, M.2
Kokubu, A.3
Sakamoto, M.4
Hirohashi, S.5
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