Common mechanisms of inhibition for the na+/glucose (hSGLT1) and Na+/Cl-/GABA (hGAT1) cotransporters

British Journal of Pharmacology

Volumn 134, Issue 3, 2001, Pages 484-495

  Hirayama, B A ^a   Diez Sampedro A ^a   Wright, E M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Electrophysiology; GABA; Glucose; Inhibitor binding; Pharmacophore; Sodium; Sodium substrate cotransport

Indexed keywords

1 (4,4 DIPHENYL 3 BUTENYL)NIPECOTIC ACID; 4 AMINOBUTYRIC ACID DERIVATIVE; BACLOFEN; CARRIER PROTEIN; ESCULIN; GALACTOSE; GLUCOPYRANOSIDE; GLUCOSE DERIVATIVE; NIPECOTIC ACID; NORTRIPTYLINE; PHLORIZIN; PROTEIN GAT1; SODIUM GLUCOSE COTRANSPORTER 1; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID UPTAKE; ANIMAL CELL; ARTICLE; BINDING KINETICS; CHLORIDE TRANSPORT; CONJUGATE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG MECHANISM; ELECTROPHYSIOLOGY; FEMALE; GLUCOSE TRANSPORT; HYDROPHOBICITY; NONHUMAN; OOCYTE; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN CONFORMATION; SODIUM TRANSPORT; STRUCTURE ACTIVITY RELATION; XENOPUS LAEVIS;

EID: 0034779753     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704274     Document Type: Article

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