Tripolin A, a Novel Small-Molecule Inhibitor of Aurora A Kinase, Reveals New Regulation of HURP's Distribution on Microtubules

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Kesisova, Iliana A ^a   Nakos, Konstantinos C ^a   Tsolou, Avgi ^a   Angelis, Dimitrios ^a   Lewis, Joe ^b   Chatzaki, Aikaterini ^a   Agianian, Bogos ^a   Giannis, Athanassios ^c   Koffa, Maria D ^a  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2,5 DIHYDROXYBENZYLIDENE) 1,3 DIHYDROINDOL 1 ONE; 3 (3H IMIDAZOL 4 YLMETHYLENE) 1,3 DIHYDROINDOL 2 ONE; 4 [[9 CHLORO 7 (2,6 DIFLUOROPHENYL) 5H PYRIMIDO[5,4 D][2]BENZAZEPIN 2 YL]AMINO]BENZOIC ACID; ALISERTIB; AURORA A KINASE; AURORA KINASE INHIBITOR; HEPATOMA UPREGULATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN SERINE THREONINE KINASE INHIBITOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL SIZE; CENTROSOME; COMPUTER MODEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; IN VITRO STUDY; IN VIVO STUDY; INTERPHASE; MICROTUBULE; RNA INTERFERENCE;

DRUG DISCOVERY; HELA CELLS; HUMANS; HYDROQUINONES; INDOLES; MICROTUBULES; MITOSIS; PROTEIN KINASE INHIBITORS; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES;

EID: 84874855139     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058485     Document Type: Article

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