-
1
-
-
34147181610
-
The progression of Parkinson disease: A hypothesis
-
DOI 10.1212/01.wnl.0000257110.91041.5d, PII 0000611420070320000017
-
Lang AE (2007) The progression of Parkinson disease: A hypothesis. Neurology, 68, 948-952. (Pubitemid 46568509)
-
(2007)
Neurology
, vol.68
, Issue.12
, pp. 948-952
-
-
Lang, A.E.1
-
2
-
-
33745847479
-
Diagnosis and treatment of Parkinson disease: Molecules to medicine
-
DOI 10.1172/JCI29178
-
Savitt JM, Dawson VL, & Dawson TM (2006) Diagnosis and treatment of Parkinson disease: Molecules to medicine. J Clin Invest, 116, 1744-1754. (Pubitemid 44033293)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1744-1754
-
-
Savitt, J.M.1
Dawson, V.L.2
Dawson, T.M.3
-
3
-
-
0034613450
-
Characterization of isolated alpha-synuclein filaments from substantia nigra of Parkinson's disease brain
-
Crowther RA, Daniel SE, & Goedert M (2000) Characterization of isolated alpha-synuclein filaments from substantia nigra of Parkinson's disease brain. Neurosci Lett, 92(2), 128-130.
-
(2000)
Neurosci Lett
, vol.92
, Issue.2
, pp. 128-130
-
-
Crowther, R.A.1
Daniel, S.E.2
Goedert, M.3
-
4
-
-
0036278335
-
Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson disease
-
DOI 10.1038/nm0602-600
-
Xu J, Kao SY, Lee FJ, Song W, Jin LW, & Yanker BA (2002) Dopamine-dependent neurotoxicity of alpha-synuclein: A mechanism for selective neurodegeneration in Parkinson disease. Nat Med, 8, 600-606. (Pubitemid 34633438)
-
(2002)
Nature Medicine
, vol.8
, Issue.6
, pp. 600-606
-
-
Xu, J.1
Kao, S.-Y.2
Lee, F.J.S.3
Song, W.4
Jin, L.-W.5
Yankner, B.A.6
-
5
-
-
0033825627
-
Oxidative stress andgenetics in the pathogenesis of Parkinson's disease
-
Zhang Y, Dawson VL, & Dawson TM (2000) Oxidative stress andgenetics in the pathogenesis of Parkinson's disease. Neu-robiol Dis, 7(4), 240-250.
-
(2000)
Neu-robiol Dis
, vol.7
, Issue.4
, pp. 240-250
-
-
Zhang, Y.1
Dawson, V.L.2
Dawson, T.M.3
-
6
-
-
57649155208
-
Oxidative Stress in Parkinson's Disease: A mechanism of pathogenic and therapeutic significance
-
Zhou C, Huang Y, & Przedborski (2008) Oxidative Stress in Parkinson's Disease: A mechanism of pathogenic and therapeutic significance. Annals of the New York Academy of Sciences, 1147, 93-104.
-
(2008)
Annals of the New York Academy of Sciences
, vol.1147
, pp. 93-104
-
-
Zhou, C.1
Huang, Y.2
Przedborski3
-
7
-
-
25144468525
-
To be or not to be (inflamed) - Is that the question in anti-inflammatory drug therapy of neurodegenerative disorders?
-
DOI 10.1016/j.tips.2005.08.007, PII S0165614705002051
-
Marchetti B, & Abbracchio MP (2005) To be or not to be (inflamed) Is that the question in anti-inflammatory drug therapy of neurodegenerative disorders? Trends Pharmacol Sci, 26, 517-525. (Pubitemid 41338562)
-
(2005)
Trends in Pharmacological Sciences
, vol.26
, Issue.10
, pp. 517-525
-
-
Marchetti, B.1
Abbracchio, M.P.2
-
8
-
-
0344198025
-
Mechanism of Toxicity in Rotenone Models of Parkinson's Disease
-
Sherer TB, Betarbet R, Testa CM, Seo BB, Richardson JR, Kim JH, Miller GW, Yagi T, Matsuno-Yagi A, & Greenamyre JT (2003) Mechanism of toxicity in rotenone models of Parkinson's disease. The Journal of Neuroscience, 23(34), 10756-10764. (Pubitemid 37499681)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.34
, pp. 10756-10764
-
-
Sherer, T.B.1
Betarbet, R.2
Testa, C.M.3
Seo, B.B.4
Richardson, J.R.5
Kim, J.H.6
Miller, G.W.7
Yagi, T.8
Matsuno-Yagi, A.9
Greenamyre, J.T.10
-
9
-
-
0029068871
-
Identification and inhibition ofthe ICE/CED-3 protease necessary for mammalian apoptosis
-
Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M, Gareau Y, Griffin PR, Labelle M, & Lazebnik YA et al. (1995) Identification and inhibition ofthe ICE/CED-3 protease necessary for mammalian apoptosis. Nature, 376, 37-43.
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
-
10
-
-
0028967848
-
Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apopto-sis
-
Slater AF, Nobel CS, Maellaro E, Bustamante J, Kimland M, & Orrenius S (1995) Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apopto-sis. Biochem J, 306, 771-778.
-
(1995)
Biochem J
, vol.306
, pp. 771-778
-
-
Slater, A.F.1
Nobel, C.S.2
Maellaro, E.3
Bustamante, J.4
Kimland, M.5
Orrenius, S.6
-
11
-
-
0033956743
-
Cytotoxicity, genotoxicity and oxidative reactions in cell-culture models: Modulatory effects of phytochemicals
-
O'Brien NM, Woods JA, Aherne SA, & O'Callaghan YC (2000) Cytotoxicity, genotoxicity and oxidative reactions in cell-culture models: Modulatory effects of phytochemicals. Biochem Soc Trans, 28, 22-26. (Pubitemid 30103207)
-
(2000)
Biochemical Society Transactions
, vol.28
, Issue.2
, pp. 22-26
-
-
O'Brien, N.M.1
Woods, J.A.2
Aherne, S.A.3
O'Callaghan, Y.C.4
-
12
-
-
0035815285
-
Release and aggregation of cytochrome c and α-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole
-
DOI 10.1016/S0014-2999(01)00902-5, PII S0014299901009025
-
Kakimura J, Kitamura Y, Takata K, Kohno Y, Nomura Y, & Taniguchi T (2001) Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole. Eur J Pharmacol, 417(1-2), 59-67. (Pubitemid 32299869)
-
(2001)
European Journal of Pharmacology
, vol.417
, Issue.1-2
, pp. 59-67
-
-
Kakimura, J.-I.1
Kitamura, Y.2
Takata, K.3
Kohno, Y.4
Nomura, Y.5
Taniguchi, T.6
-
14
-
-
0032879452
-
Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease
-
Hashimoto M, Takeda A, Hsu LJ, Takenouchi T, & Masliah E (1999) Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease. J Biol Chem, 274(41), 28849-28852.
-
(1999)
J Biol Chem
, vol.274
, Issue.41
, pp. 28849-28852
-
-
Hashimoto, M.1
Takeda, A.2
Hsu, L.J.3
Takenouchi, T.4
Masliah, E.5
-
15
-
-
0031036896
-
Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease
-
Anglade P, Vyas S, Javoy-Agid F, Herrero MT, Michel PP, Marquez J, Mouatt-Prigent A, Ruberg M, Hirsch EC, & Agid Y (1997) Apoptosis and autophagy in nigral neurons of patientswith Parkinson's disease. Histol Histopathol, 12, 25-31. (Pubitemid 27106916)
-
(1997)
Histology and Histopathology
, vol.12
, Issue.1
, pp. 25-31
-
-
Anglade, P.1
-
16
-
-
0029942337
-
Histochemical detection of apoptosis in Parkinson's disease
-
DOI 10.1016/0022-510X(95)00336-Z
-
Mochizuki H, Goto K, Mori H, & Mizuno Y (1996) His-tochemical detection of apoptosis in Parkinson's disease. J Neurol Sci, 137, 120-123. (Pubitemid 26172041)
-
(1996)
Journal of the Neurological Sciences
, vol.137
, Issue.2
, pp. 120-123
-
-
Mochizuki, H.1
Goto, K.2
Mori, H.3
Mizuno, Y.4
-
17
-
-
0028222824
-
+) in ventral mesencephalic-striatal co-culture in rat
-
DOI 10.1016/0304-3940(94)90271-2
-
Mochizuki H, Nakamura N, Nishi K, & Mizuno Y (1994) Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat. Neurosci Lett, 170, 191-194. (Pubitemid 24117319)
-
(1994)
Neuroscience Letters
, vol.170
, Issue.1
, pp. 191-194
-
-
Mochizuki, H.1
Nakamura, N.2
Nishi, K.3
Mizuno, Y.4
-
18
-
-
0036716889
-
MPTP: Insights into parkinsonian neu-rodegeneration
-
Speciale SG (2002) MPTP: Insights into parkinsonian neu-rodegeneration. Neurotoxicol Teratol, 24, 607-620.
-
(2002)
Neurotoxicol Teratol
, vol.24
, pp. 607-620
-
-
Speciale, S.G.1
-
19
-
-
0030888286
-
In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
-
Tatton NA, & Kish SJ (1997) In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1, 2, 3, 6- tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining. Neuroscience, 77, 1037-1048.
-
(1997)
Neuroscience
, vol.77
, pp. 1037-1048
-
-
Tatton, N.A.1
Kish, S.J.2
-
20
-
-
0025116342
-
Mechanism of the neuro-toxicity of MPTP, an update
-
Singer TP, & Ramsay RR (1990) Mechanism of the neuro-toxicity of MPTP, an update. FEBS Lett, 274, 1-8.
-
(1990)
FEBS Lett
, vol.274
, pp. 1-8
-
-
Singer, T.P.1
Ramsay, R.R.2
-
21
-
-
0035022949
-
+ neurotoxicity in mice
-
DOI 10.1023/A:1007680616056
-
Alcaraz-Zubeldia M, Rojas P, Boll C, & Rios C (2001) Neuro-protective effect of acute and chronic administration of copper (II) sulfate against MPP+ neurotoxicity in mice. Neurochem Res, 26, 59-64. (Pubitemid 32428814)
-
(2001)
Neurochemical Research
, vol.26
, Issue.1
, pp. 59-64
-
-
Alcaraz-Zubeldia, M.1
Rojas, P.2
Boll, C.3
Rios, C.4
-
22
-
-
0033840581
-
2-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo
-
DOI 10.1046/j.1471-4159.2000.0751200.x
-
Saporito MS, Thomas BA, Scott RW (2000) MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo. J Neurochem, 75, 1200-1208. (Pubitemid 30660510)
-
(2000)
Journal of Neurochemistry
, vol.75
, Issue.3
, pp. 1200-1208
-
-
Saporito, M.S.1
Thomas, B.A.2
Scott, R.W.3
-
24
-
-
0037085288
-
Formation and removal of α-synuclein aggregates in cells exposed to mitochondrial inhibitors
-
DOI 10.1074/jbc.M105326200
-
Lee HJ, Shin SY, Choi C, Lee YH, & Lee SJ (2002) Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors. J Biol Chem, 277, 5411-5417. (Pubitemid 34968588)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.7
, pp. 5411-5417
-
-
Lee, H.-J.1
Shin, S.Y.2
Choi, C.3
Lee, Y.H.4
Lee, S.-J.5
-
25
-
-
2442494278
-
+-induced apoptosis in neuroblastoma cells. Intermediacy of transferrin receptor iron and hydrogen peroxide
-
DOI 10.1074/jbc.M312497200
-
Kalivendi SV, Cunningham S, Kotamraju S, Joseph J, Hillard CJ, & Kalyanaraman B (2004) Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neurob-lastoma cells: Intermediacy of transferrin receptor iron and hydrogen peroxide. J Biol Chem, 279, 15240-15247. (Pubitemid 38618920)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.15
, pp. 15240-15247
-
-
Kalivendi, S.V.1
Cunningham, S.2
Kotamraju, S.3
Joseph, J.4
Hillard, C.J.5
Kalyanaraman, B.6
-
26
-
-
56349089470
-
Role of nitric oxide synthases in Parkinson's disease: A review on the antioxidantand anti-inflammatory activityofpolyphenols
-
Aquilano K, Baldelli S, Rotilio G, & Ciriolo MR (2008) Role of nitric oxide synthases in Parkinson's disease: A review on the antioxidantand anti-inflammatory activityofpolyphenols. Neurochem Res, 33, 2416-2426.
-
(2008)
Neurochem Res
, vol.33
, pp. 2416-2426
-
-
Aquilano, K.1
Baldelli, S.2
Rotilio, G.3
Ciriolo, M.R.4
-
27
-
-
33750465142
-
Nitric oxide synthase regulation and diversity: Implications in Parkinson's disease
-
DOI 10.1016/j.niox.2006.07.003, PII S1089860306003764
-
Kavya R, Saluja R, Singh, & Dikshit SM (2006) Nitric oxide synthase regulation and diversity: Implications in Parkinson's disease. Nitric Oxide, 15, 280-294. (Pubitemid 44647899)
-
(2006)
Nitric Oxide - Biology and Chemistry
, vol.15
, Issue.4
, pp. 280-294
-
-
Kavya, R.1
Saluja, R.2
Singh, S.3
Dikshit, M.4
-
28
-
-
0032710609
-
Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
-
Liberatore GT, Jackson-Lewis V, Vukosavic S, Mandir AS, Vila M, McAuliffe WG, Dawson VL, Dawson TM, & Przed-borski S (1999) Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. Nat Med, 5, 1403-1409.
-
(1999)
Nat Med
, vol.5
, pp. 1403-1409
-
-
Liberatore, G.T.1
Jackson-Lewis, V.2
Vukosavic, S.3
Mandir, A.S.4
Vila, M.5
McAuliffe, W.G.6
Dawson, V.L.7
Dawson, T.M.8
Przed-Borski, S.9
-
29
-
-
23844506517
-
+-induced neurotoxicity in PC12 cells
-
DOI 10.1016/j.neuro.2004.12.008, PII S0161813X05000045
-
Xu Z, Cawthon D, McCastlain KA, Duhart HM, Newport GD, Fang H, Patterson TA, Slikker W Jr, & Ali SF (2005) Selective alterationsoftranscription factorsinMPP+-induced neurotoxicity in PC12 cells. Neurotoxicology, 26, 729-737. (Pubitemid 41175905)
-
(2005)
NeuroToxicology
, vol.26
, Issue.4 SPEC. ISSUE
, pp. 729-737
-
-
Xu, Z.1
Cawthon, D.2
McCastlain, K.A.3
Duhart, H.M.4
Newport, G.D.5
Fang, H.6
Patterson, T.A.7
Slikker Jr., W.8
Ali, S.F.9
-
30
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
DOI 10.1016/S0896-6273(03)00568-3
-
Dauer W, & Przedborski S (2003) Parkinson's disease: Mechanisms and models. Neuron, 39, 889-909. (Pubitemid 37130207)
-
(2003)
Neuron
, vol.39
, Issue.6
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
31
-
-
33745013111
-
Oxidative stress and neurodegeneration: Where are we now?
-
DOI 10.1111/j.1471-4159.2006.03907.x
-
Halliwell B (2006) Oxidative stress and neurodegeneration: Where are we now? J Neurochem, 97(6), 1634-1658. (Pubitemid 43873658)
-
(2006)
Journal of Neurochemistry
, vol.97
, Issue.6
, pp. 1634-1658
-
-
Halliwell, B.1
-
32
-
-
77950363010
-
Mechanisms Underlying Inflammation in Neurodegeneration
-
Glass CK, Saijo K, Winner B, Marchetto MC, & Gage FH (2010) Mechanisms Underlying Inflammation in Neurodegeneration. Cell, 140(6), 918-934.
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 918-934
-
-
Glass, C.K.1
Saijo, K.2
Winner, B.3
Marchetto, M.C.4
Gage, F.H.5
-
33
-
-
0033637140
-
The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
-
Middleton E Jr, Kandaswami C, & Theoharides TC (2000) The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol Rev, 52, 673-751.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 673-751
-
-
Middleton Jr., E.1
Kandaswami, C.2
Theoharides, T.C.3
-
34
-
-
0035004114
-
Flavonoid antioxidants
-
Rice-Evans C (2001) Flavonoid antioxidants. Curr Med Chem, 8(7), 797-807. (Pubitemid 32427907)
-
(2001)
Current Medicinal Chemistry
, vol.8
, Issue.7
, pp. 797-807
-
-
Rice-Evans, C.1
-
35
-
-
0035235476
-
Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons
-
Bastianetto S, Zheng WH, & Quirion R (2000) Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons. Br J Pharmacol, 131(4), 711-720.
-
(2000)
Br J Pharmacol
, vol.131
, Issue.4
, pp. 711-720
-
-
Bastianetto, S.1
Zheng, W.H.2
Quirion, R.3
-
36
-
-
3142540615
-
Investigations on the binding and antioxidant properties of the plant flavonoid fisetin in model biomembranes
-
DOI 10.1016/j.febslet.2004.06.027, PII S0014579304007483
-
Sengupta B, Banerjee A, & Sengupta PK (2004) Investigations on the binding and antioxidant properties of the plant flavonoid fisetin in model biomembranes. FEBS Letters, 570, 77-81. (Pubitemid 38900960)
-
(2004)
FEBS Letters
, vol.570
, Issue.1-3
, pp. 77-81
-
-
Sengupta, B.1
Banerjee, A.2
Sengupta, P.K.3
-
37
-
-
0033850592
-
Dietary intakes of flavonols, flavones and isoflavones by Japanese women and the inverse correlation between quercetin intake and plasma LDL cholesterol concentration
-
Arai Y, Watanabe S, Kimira M, Shimoi K, Mochizuki R, & Kinae N (2000) Dietary intakes of flavonols, flavones and isoflavones by Japanese women and the inverse correlation between quercetin intake and plasma LDL cholesterol concentration. J Nutr, 130(9), 2243-2250.
-
(2000)
J Nutr
, vol.130
, Issue.9
, pp. 2243-2250
-
-
Arai, Y.1
Watanabe, S.2
Kimira, M.3
Shimoi, K.4
Mochizuki, R.5
Kinae, N.6
-
38
-
-
71949125029
-
Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin
-
Maher P (2009) Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin. Genes Nutr, 4(4), 297-307.
-
(2009)
Genes Nutr
, vol.4
, Issue.4
, pp. 297-307
-
-
Maher, P.1
-
39
-
-
25444508963
-
Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease
-
DOI 10.1080/10715760500233113
-
Zbarsky V, Datla KP, Parkar S, Rai DK, Aruoma OI, & Dexter DT (2005) Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease. Free Radic Res, 39(10), 1119-1125. (Pubitemid 41358566)
-
(2005)
Free Radical Research
, vol.39
, Issue.10
, pp. 1119-1125
-
-
Zbarsky, V.1
Datla, K.P.2
Parkar, S.3
Rai, D.K.4
Aruoma, O.I.5
Dexter, D.T.6
-
40
-
-
4043089112
-
Pharmacokinetics and Metabolism of dietary fiavonoids
-
Manach C, & Donovan J (2004) Pharmacokinetics and Metabolism of dietary fiavonoids. Free Rad Res, 38, 771-785.
-
(2004)
Free Rad Res
, vol.38
, pp. 771-785
-
-
Manach, C.1
Donovan, J.2
-
41
-
-
0035865819
-
Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms
-
DOI 10.1016/S0891-5849(00)00498-6, PII S0891584900004986
-
Ishige K, Schubert D, & Sagara Y (2001) Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms. Free Radic Biol Med, 30(4), 433-446. (Pubitemid 32155542)
-
(2001)
Free Radical Biology and Medicine
, vol.30
, Issue.4
, pp. 433-446
-
-
Ishige, K.1
Schubert, D.2
Sagara, Y.3
-
42
-
-
4444360215
-
Induction of PC12 cell differentiation by flavonoids is dependent upon extracellular signal-regulated kinase activation
-
DOI 10.1111/j.1471-4159.2004.02563.x
-
Sagara Y, Vanhnasy J, & Maher P. (2004) Induction of PC12 cell differentiation by flavonoids is dependent upon extracellular signal-regulated kinase activation. J Neurochem, 90(5), 1144-1155. (Pubitemid 39167347)
-
(2004)
Journal of Neurochemistry
, vol.90
, Issue.5
, pp. 1144-1155
-
-
Sagara, Y.1
Vanhnasy, J.2
Maher, P.3
-
43
-
-
33749255399
-
A comparison of the neurotrophic activities of the flavonoid fisetin and some of its derivatives
-
DOI 10.1080/10715760600672509, PII W1255U116263V742, Polyphenols and Health
-
Maher P (2006) A comparison of the neurotrophic activities of the flavonoid fisetin and some of its derivatives. Free Radic Res, 40(10), 1105-1111. (Pubitemid 44480551)
-
(2006)
Free Radical Research
, vol.40
, Issue.10
, pp. 1105-1111
-
-
Maher, P.1
-
44
-
-
48149095229
-
The flavonoid fisetin promotes nerve cell survival from trophic withdrawal by enhancement of proteasome activity
-
Maher P (2008) The flavonoid fisetin promotes nerve cell survival from trophic withdrawal by enhancement of proteasome activity. Arch Biochem Biophys, 476, 139-144.
-
(2008)
Arch Biochem Biophys
, vol.476
, pp. 139-144
-
-
Maher, P.1
-
45
-
-
2442507000
-
Affordable image analysis using NIH image/imageJ
-
Girish V, & Vijayalakshmi A (2004) Affordable image analysis using NIH Image/ImageJ. Indian J Cancer, 41, 47. (Pubitemid 38623932)
-
(2004)
Indian Journal of Cancer
, vol.41
, Issue.1
, pp. 47
-
-
Girish, V.1
Vijayalakshmi, A.2
-
47
-
-
23444455247
-
Dopamine promotes α-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway
-
DOI 10.1096/fj.04-3437fje
-
Cappai R, Leck SL, Tew DJ, Williamson NA, Smith DP, Galattis D, Sharples RA, Curtain CC, Ali FE, Cherry RA, Cul-vernor JG, Bottomley SP, Masters CL, Barnham KJ, & Hill AF (2005) Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway. FASEB J, 9, 1377-1379. (Pubitemid 41113755)
-
(2005)
FASEB Journal
, vol.19
, Issue.10
, pp. 1377-1379
-
-
Cappai, R.1
Leek, S.-L.2
Tew, D.J.3
Williamson, N.A.4
Smith, D.P.5
Galatis, D.6
Sharples, R.A.7
Curtain, C.C.8
Ali, F.E.9
Cherny, R.A.10
Culvenor, J.G.11
Bottomley, S.P.12
Masters, C.L.13
Barnham, K.J.14
Hill, A.F.15
-
48
-
-
2342650150
-
2, Hydrogen Peroxide, and a Nitric Oxide Donor in Differentiated Neuroblastoma Cells
-
DOI 10.1002/jnr.20058
-
Prasad JE, Kumar B, Andreatta C, Nahreini P, Hanson AJ, Yan XD, & Prasad KN (2004) Overexpression of alpha-synuclein decreased viability and enhanced sensitivity to prostaglandin E(2), hydrogen peroxide, and a nitric oxide donor in differentiated neuroblastoma cells. J Neurosci Res, 76, 415-422. (Pubitemid 38580137)
-
(2004)
Journal of Neuroscience Research
, vol.76
, Issue.3
, pp. 415-422
-
-
Prasad, J.E.1
Kumar, B.2
Andreatta, C.3
Nahreini, P.4
Hanson, A.J.5
Yan, X.D.6
Prasad, K.N.7
-
49
-
-
0031172065
-
NF-κB: A crucial transcription factor for glial and neuronal cell function
-
DOI 10.1016/S0166-2236(96)01035-1
-
O'Neill Luke AJ, & Kaltschmidt C (1997) NF-kB: A crucial transcription factor for glial and neuronal cell function. Trends Neurosci, 20, 252-258. (Pubitemid 27261456)
-
(1997)
Trends in Neurosciences
, vol.20
, Issue.6
, pp. 252-258
-
-
O'Neill, L.A.J.1
Kaltschmidt, C.2
-
50
-
-
33646010041
-
Roles for NF-kB in nerve cell survival, plasticity, and disease
-
Mattson MP, & Meffert MK (2006) Roles for NF-kB in nerve cell survival, plasticity, and disease. Cell Death Differ, 13, 852-860.
-
(2006)
Cell Death Differ
, vol.13
, pp. 852-860
-
-
Mattson, M.P.1
Meffert, M.K.2
-
51
-
-
34250016055
-
Apoptotic neuronal death in Parkinson's disease: Involvement of nitric oxide
-
DOI 10.1016/j.brainresrev.2007.02.001, PII S0165017307000276
-
Singh S, & Dikshit M (2007) Apoptotic neuronal death in Parkinson's disease: Involvement of nitric oxide. Brain Research Reviews, 54(2), 233-250. (Pubitemid 46891075)
-
(2007)
Brain Research Reviews
, vol.54
, Issue.2
, pp. 233-250
-
-
Singh, S.1
Dikshit, M.2
-
52
-
-
0027130238
-
Bcl-2/Bax - A rheostat that regulates an anti-oxidant pathway and cell death
-
Korsmeyer SJ, Shutter JR, Veis DJ, Merry DE, & Oltvai ZN (1993) Bcl-2/Bax: A rheostat that regulates an anti-oxidant pathway and cell death. Semin Cancer Biol, 4, 327-332. (Pubitemid 2028596)
-
(1993)
Seminars in Cancer Biology
, vol.4
, Issue.6
, pp. 327-332
-
-
Korsmeyer, S.J.1
Shutter, J.R.2
Veis, D.J.3
Merry, D.E.4
Oltvai, Z.N.5
-
53
-
-
84975751684
-
Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: Relevance to Parkinson's disease
-
Hartley A, Stone JM, Heron C, Cooper JM, & Schapira AH (1994) Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: Relevance to Parkinson's disease. JNeurochem, 63, 1987-1990. (Pubitemid 24326248)
-
(1994)
Journal of Neurochemistry
, vol.63
, Issue.5
, pp. 1987-1990
-
-
Hartley, A.1
Stone, J.M.2
Heron, C.3
Cooper, J.M.4
Schapira, A.H.V.5
-
54
-
-
79953869870
-
Attenuation of LPS-induced apoptosis in NGF-differentiated PC12 cells via NF-kB pathway and regulation of cellular redox status by an oxazine derivative
-
Ansari N, Khodagholi F, Amini M, & Shaerzadeh F (2011) Attenuation of LPS-induced apoptosis in NGF-differentiated PC12 cells via NF-kB pathway and regulation of cellular redox status by an oxazine derivative. Biochimie, 93(5), 899-908.
-
(2011)
Biochimie
, vol.93
, Issue.5
, pp. 899-908
-
-
Ansari, N.1
Khodagholi, F.2
Amini, M.3
Shaerzadeh, F.4
-
55
-
-
79957939863
-
Protective effect of diosmin on LPS-induced apoptosis in PC12 cells and inhibition of TNF-a expression
-
Dholakiya SL, & Benzeroual KE (2011) Protective effect of diosmin on LPS-induced apoptosis in PC12 cells and inhibition of TNF-a expression. Toxicology In Vitro, 25(5), 1039-1044.
-
(2011)
Toxicology in Vitro
, vol.25
, Issue.5
, pp. 1039-1044
-
-
Dholakiya, S.L.1
Benzeroual, K.E.2
-
56
-
-
0035894881
-
Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease
-
Viswanath V, Wu Y, Boonplueang R, Chen S, Stevenson FF, Yantiri F, Yang L, Flint Beal M, & Andersen JK (2001) Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced Parkinson's disease. The Journal of Neuroscience, 21(24), 9519-9528. (Pubitemid 34184040)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.24
, pp. 9519-9528
-
-
Viswanath, V.1
Wu, Y.2
Boonplueang, R.3
Chen, S.4
Stevenson, F.F.5
Yantiri, F.6
Yang, L.7
Flint Beal, M.8
Andersen, J.K.9
-
57
-
-
70450223158
-
The neuroprotective potential of flavonoids: A multiplicity of effects
-
Vauzour D, Vafeiadou K, Rodriguez-Mateos A, Rendeiro C, & Spencer JPE (2008) The neuroprotective potential of flavonoids: A multiplicity of effects. GenesNutr, 3(3-4), 115-126.
-
(2008)
GenesNutr
, vol.3
, Issue.3-4
, pp. 115-126
-
-
Vauzour, D.1
Vafeiadou, K.2
Rodriguez-Mateos, A.3
Rendeiro, C.4
Spencer, J.P.E.5
-
58
-
-
33847265732
-
Rifampicin protects PC12 cells against MPP+ induced apoptosis and inhibits expression of alpha-Synuclein oligomers
-
Xua J, Weib C, Xuc C, Bennettc CM, Zhanga G, Lia F, & Taoa E (2007) Rifampicin protects PC12 cells against MPP+ induced apoptosis and inhibits expression of alpha-Synuclein oligomers. Brain Research, 1139, 220-225.
-
(2007)
Brain Research
, vol.1139
, pp. 220-225
-
-
Xua, J.1
Weib, C.2
Xuc, C.3
Bennettc, C.M.4
Zhanga, G.5
Lia, F.6
Taoa, E.7
-
59
-
-
0033966487
-
α-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP
-
DOI 10.1046/j.1471-4159.2000.740721.x
-
Vila M, Vukosavic S, Jackson-Lewis V, Neystat M, Jakowec M, & Przedborski S (2000) a-Synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP J Neurochem, 74, 721-729. (Pubitemid 30053745)
-
(2000)
Journal of Neurochemistry
, vol.74
, Issue.2
, pp. 721-729
-
-
Vila, M.1
Vukosavic, S.2
Jackson-Lewis, V.3
Neystat, M.4
Jakowec, M.5
Przedborski, S.6
-
60
-
-
0033890821
-
α-synuclein promotes mitochondrial deficit and oxidative stress
-
Hsu LJ, Sagara Y, Arroyo A, Rockenstein E, Sisk A, Mal-lory M, Wong J, Takenouchi T, Hashimoto M, & Masliah E (2000) Alpha-synuclein promotes mitochondrial deficit and oxidative stress. Am J Pathol, 157, 401-410. (Pubitemid 30627559)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.2
, pp. 401-410
-
-
Hsu, L.J.1
Sagara, Y.2
Arroyo, A.3
Rockenstein, E.4
Sisk, A.5
Mallory, M.6
Wong, J.7
Takenouchi, T.8
Hashimoto, M.9
Masliah, E.10
-
61
-
-
12244300931
-
Mechanisms of MPTP toxicity and their implications for therapy of Parkinson's disease
-
Watanabe Y, Himeda T, & Araki T (2005) Mechanisms of MPTP toxicity and their implications for therapy of Parkinson's disease. Med Sci Monit, 11, RA17-RA23. (Pubitemid 40116407)
-
(2005)
Medical Science Monitor
, vol.11
, Issue.1
-
-
Watanabe, Y.1
Himeda, T.2
Araki, T.3
-
62
-
-
0033821703
-
Induction of neuronal death by alpha-synuclein
-
Saha AR, Ninkina NN, Hanger DP, Anderton BH, Davies AM, & Buchman VL (2000) Induction of neuronal death by alpha-synuclein. Eur J Neurosci, 12, 3073-3077.
-
(2000)
Eur J Neurosci
, vol.12
, pp. 3073-3077
-
-
Saha, A.R.1
Ninkina, N.N.2
Hanger, D.P.3
Anderton, B.H.4
Davies, A.M.5
Buchman, V.L.6
-
63
-
-
29644434199
-
Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity
-
DOI 10.1093/hmg/ddi396
-
Smith WW, Jiang H, Pei Z, Tanaka Y, Morita H, Sawa A, Dawson VL, Dawson TM, & Ross CA (2005) Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity. Hum Mol Genet, 14, 3801-3811. (Pubitemid 43020082)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.24
, pp. 3801-3811
-
-
Smith, W.W.1
Jiang, H.2
Pei, Z.3
Tanaka, Y.4
Morita, H.5
Sawa, A.6
Dawson, V.L.7
Dawson, T.M.8
Ross, C.A.9
-
64
-
-
0032006868
-
Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells
-
DOI 10.1002/(SICI)1097-4547(19980201)51:3<293::AID-JNR3>3.0.CO;2-B
-
Kruman I, Guo Q, & Mattson MP (1998) Calcium andreactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells. J Neurosci Res, 51, 293-308. (Pubitemid 28078461)
-
(1998)
Journal of Neuroscience Research
, vol.51
, Issue.3
, pp. 293-308
-
-
Kruman, I.1
Guo, Q.2
Mattson, M.P.3
-
65
-
-
0037441753
-
The establishment of a reliable cytotoxic system with SK-N-SH neuroblastoma cell culture
-
DOI 10.1016/S0165-0270(02)00324-2, PII S0165027002003242
-
Ba F, Pang PKT, & Benishin CG (2003) The establishment of a reliable cytotoxic system with SK-N-SH neuroblastoma cell culture. Journal of Neuroscience Methods, 123(1), 11-22. (Pubitemid 36173648)
-
(2003)
Journal of Neuroscience Methods
, vol.123
, Issue.1
, pp. 11-22
-
-
Ba, F.1
Pang, P.K.T.2
Benishin, C.G.3
-
66
-
-
79953150761
-
Parkinsonian neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) and a-synuclein mutations promote tau protein phosphorylation at Ser262 and destabilize microtubule cytoskeleton in Vitro
-
Qureshi HY, & Paudel HK (2011) Parkinsonian neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) and a-synuclein mutations promote tau protein phosphorylation at Ser262 and destabilize microtubule cytoskeleton in Vitro. J Biol Chem, 286(7), 5055-5068.
-
(2011)
J Biol Chem
, vol.286
, Issue.7
, pp. 5055-5068
-
-
Qureshi, H.Y.1
Paudel, H.K.2
-
67
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A, McDonnell JM, & Korsmeyer SJ (1999) Bcl-2 family members and the mitochondria in apoptosis. Genes Dev, 13, 1899-1911. (Pubitemid 29407357)
-
(1999)
Genes and Development
, vol.13
, Issue.15
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
69
-
-
0043162103
-
Novel anti-inflammatory therapy for Parkinson's disease
-
DOI 10.1016/S0165-6147(03)00176-7
-
Gao HM, Liu B, Zhang W, & Hong JS (200) (2003) Novel anti-inflammatory therapy for Parkinson's disease. Trends in Pharmacological Sciences, 24(8), 395-401. (Pubitemid 36952555)
-
(2003)
Trends in Pharmacological Sciences
, vol.24
, Issue.8
, pp. 395-401
-
-
Gao, H.-M.1
Liu, B.2
Zhang, W.3
Hong, J.-S.4
-
70
-
-
1942454250
-
Inflammation and neu-rodegeneration in Parkinson's disease
-
McGeer PL, & McGeer EG (2004) Inflammation and neu-rodegeneration in Parkinson's disease. Parkinsonism Relat Disord, 10(1), S3-S7.
-
(2004)
Parkinsonism Relat Disord
, vol.10
, Issue.1
-
-
McGeer, P.L.1
McGeer, E.G.2
-
71
-
-
35348966882
-
Neuroinflammatory mechanisms in Parkinson's disease: Potential environmental triggers, pathways, and targets for early therapeutic intervention
-
DOI 10.1016/j.expneurol.2007.07.004, PII S0014488607002701
-
Tansey MG, McCoy MK, & Frank-Cannon TC (2007) Neu-roinflammatory mechanisms in Parkinson's disease: Potential environmental triggers, pathways, and targets for early therapeutic intervention. Exp Neurol, 208(1), 1-25. (Pubitemid 47603240)
-
(2007)
Experimental Neurology
, vol.208
, Issue.1
, pp. 1-25
-
-
Tansey, M.G.1
McCoy, M.K.2
Frank-Cannon, T.C.3
-
72
-
-
0037031609
-
Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra
-
DOI 10.1016/S0304-3940(02)00704-8, PII S0304394002007048
-
Feng ZH, Wang TG, Li DD, Fung P, Wilson BC, Liu B, Ali SF, Langenbach R, & Hong JS (2002) Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra. Neurosci Lett, 329, 354-358. (Pubitemid 35245358)
-
(2002)
Neuroscience Letters
, vol.329
, Issue.3
, pp. 354-358
-
-
Feng, Z.-H.1
Wang, T.-G.2
Li, D.-D.3
Fung, P.4
Wilson, B.C.5
Liu, B.6
Ali, S.F.7
Langenbach, R.8
Hong, J.-S.9
-
73
-
-
1642395294
-
Immunofluorescent labeling of increased calpain expression and neuronal death in the spinal cord of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- treated mice
-
DOI 10.1016/j.brainres.2004.01.065, PII S0006899304001726
-
Chera B, Schaecher KE, Rocchini A, Imam SZ, Sribnick EA, Ray SK, Ali SF, & Banik NL (2004) Immunofluorescent labeling of increased calpain expression and neuronal death in the spinal cord of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-treated mice. Brain Res, 1006, 150-156. (Pubitemid 38393759)
-
(2004)
Brain Research
, vol.1006
, Issue.2
, pp. 150-156
-
-
Chera, B.1
Schaecher, K.E.2
Rocchini, A.3
Imam, S.Z.4
Sribnick, E.A.5
Ray, S.K.6
Ali, S.F.7
Banik, N.L.8
-
74
-
-
33845186388
-
L-Carnitine protects neurons from 1-methyl-4-phenylpyridinium-induced neuronal apoptosis in rat forebrain culture
-
DOI 10.1016/j.neuroscience.2006.08.083, PII S0306452206011717
-
Wang C, Sadovova N, Ali HK, Duhart HM, Fu X, Zou X, Patterson TA, Binienda ZK, Virmani A, Paule MG, Slikker W Jr, & Ali SF (2007) L-Carnitine protects neurons from 1-methyl-4-phenylpyridinium-induced neuronal apoptosis in rat forebrain culture. Neuroscience, 144, 46-55. (Pubitemid 44848384)
-
(2007)
Neuroscience
, vol.144
, Issue.1
, pp. 46-55
-
-
Wang, C.1
Sadovova, N.2
Ali, H.K.3
Duhart, H.M.4
Fu, X.5
Zou, X.6
Patterson, T.A.7
Binienda, Z.K.8
Virmani, A.9
Paule, M.G.10
Slikker Jr., W.11
Ali, S.F.12
|