l-Carnitine protects neurons from 1-methyl-4-phenylpyridinium-induced neuronal apoptosis in rat forebrain culture

Neuroscience

Volumn 144, Issue 1, 2007, Pages 46-55

  Wang, C ^a   Sadovova, N ^b   Ali, H K ^a   Duhart, H M ^a   Fu, X ^a   Zou, X ^a   Patterson, T A ^a   Binienda, Z K ^a   Virmani, A ^c   Paule, M G ^a   Slikker Jr , W ^a   Ali, S F ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b Pathology Associates International   (United States)

^c Sigma Tau SpA   (Italy)

Author keywords

1 methyl 4 phenylpyridinium ion; apoptosis; l carnitine; MPP+; neurodegeneration; neuronal rescue

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CARNITINE; DNA FRAGMENT; LACTATE DEHYDROGENASE; NERVE CELL ADHESION MOLECULE; POLYSIALIC ACID; PROTEIN BAX; PROTEIN BCL XL;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISORDERS OF AMINO ACID AND PROTEIN METABOLISM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME RELEASE; FOREBRAIN; MITOCHONDRIAL RESPIRATION; NERVE CELL; NICK END LABELING; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BLOTTING, WESTERN; CARNITINE; CELL NUCLEUS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; L-LACTATE DEHYDROGENASE; NEURONS; NEUROPROTECTIVE AGENTS; PROSENCEPHALON; RATS; RATS, SPRAGUE-DAWLEY; SIALIC ACIDS; TETRAZOLIUM SALTS; THIAZOLES;

EID: 33845186388     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.08.083     Document Type: Article

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