-
1
-
-
12144262315
-
Diet-derived phenols in plasma and tissues and their implications for health
-
MN Clifford 2004 Diet-derived phenols in plasma and tissues and their implications for health Planta Med 70 1103 1114
-
(2004)
Planta Med
, vol.70
, pp. 1103-1114
-
-
Clifford, M.N.1
-
2
-
-
0141863402
-
Overview of dietary flavonoids: Nomenclature, occurrence and intake
-
GR Beecher 2003 Overview of dietary flavonoids: nomenclature, occurrence and intake J Nutr 133 3248S 3254S
-
(2003)
J Nutr
, vol.133
-
-
Beecher, G.R.1
-
3
-
-
0033637140
-
The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
-
E Middleton Jr C Kandaswami TC Theoharides 2000 The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer Pharmacol Rev 52 673 751
-
(2000)
Pharmacol Rev
, vol.52
, pp. 673-751
-
-
Middleton Jr., E.1
Kandaswami, C.2
Theoharides, T.C.3
-
4
-
-
0033642773
-
Protection from cardiovascular disease by wine and its derived products. Epidemiological evidence and biological mechanisms
-
S Rotondo G de Gaetano 2000 Protection from cardiovascular disease by wine and its derived products. Epidemiological evidence and biological mechanisms World Rev Nutr Diet 87 90 113
-
(2000)
World Rev Nutr Diet
, vol.87
, pp. 90-113
-
-
Rotondo, S.1
De Gaetano, G.2
-
5
-
-
33747286388
-
Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: A review of their intracellular targets
-
C Ramassamy 2006 Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets Eur J Pharmacol 545 51 64
-
(2006)
Eur J Pharmacol
, vol.545
, pp. 51-64
-
-
Ramassamy, C.1
-
7
-
-
0142125716
-
Factors affecting the ascorbate- and phenolic-dependent generation of hydrogen peroxide in Dulbecco's Modified Eagles Medium
-
LM Wee LH Long M Whiteman B Halliwell 2003 Factors affecting the ascorbate- and phenolic-dependent generation of hydrogen peroxide in Dulbecco's Modified Eagles Medium Free Radic Res 37 1123 1130
-
(2003)
Free Radic Res
, vol.37
, pp. 1123-1130
-
-
Wee, L.M.1
Long, L.H.2
Whiteman, M.3
Halliwell, B.4
-
8
-
-
36749081135
-
Resveratrol as an antioxidant and pro-oxidant agent: Mechanisms and clinical implications
-
CA de la Lastra I Villegas 2007 Resveratrol as an antioxidant and pro-oxidant agent: mechanisms and clinical implications Biochem Soc Trans 35 1156 1160
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 1156-1160
-
-
De La Lastra, C.A.1
Villegas, I.2
-
9
-
-
33745534542
-
The roles of polyphenols in cancer chemoprevention
-
KW Lee HJ Lee 2006 The roles of polyphenols in cancer chemoprevention Biofactors 26 105 121
-
(2006)
Biofactors
, vol.26
, pp. 105-121
-
-
Lee, K.W.1
Lee, H.J.2
-
10
-
-
0141639855
-
Antioxidant activity of tea polyphenols in vivo: Evidence from animal studies
-
B Frei JV Higdon 2003 Antioxidant activity of tea polyphenols in vivo: evidence from animal studies J Nutr 133 3275S 3284S
-
(2003)
J Nutr
, vol.133
-
-
Frei, B.1
Higdon, J.V.2
-
11
-
-
0036774226
-
Flavonoid antioxidants: Chemistry, metabolism and structure-activity relationships
-
KE Heim AR Tagliaferro DJ Bobilya 2002 Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships J Nutr Biochem 13 572 584
-
(2002)
J Nutr Biochem
, vol.13
, pp. 572-584
-
-
Heim, K.E.1
Tagliaferro, A.R.2
Bobilya, D.J.3
-
12
-
-
0036888239
-
Direct scavenging of nitric oxide and superoxide by green tea
-
T Nakagawa T Yokozawa 2002 Direct scavenging of nitric oxide and superoxide by green tea Food Chem Toxicol 40 1745 1750
-
(2002)
Food Chem Toxicol
, vol.40
, pp. 1745-1750
-
-
Nakagawa, T.1
Yokozawa, T.2
-
14
-
-
33845211714
-
Neuroinflammation, oxidative stress and the pathogenesis of Parkinson's disease
-
RL Mosley EJ Benner I Kadiu 2006 Neuroinflammation, oxidative stress and the pathogenesis of Parkinson's disease Clin Neurosci Res 6 261 281
-
(2006)
Clin Neurosci Res
, vol.6
, pp. 261-281
-
-
Mosley, R.L.1
Benner, E.J.2
Kadiu, I.3
-
15
-
-
2442430353
-
Polyphenols: Food sources and bioavailability
-
C Manach A Scalbert C Morand 2004 Polyphenols: food sources and bioavailability Am J Clin Nutr 79 727 747
-
(2004)
Am J Clin Nutr
, vol.79
, pp. 727-747
-
-
Manach, C.1
Scalbert, A.2
Morand, C.3
-
16
-
-
33644660982
-
Green tea catechins as brain-permeable, natural iron chelators- antioxidants for the treatment of neurodegenerative disorders
-
S Mandel T Amit L Reznichenko 2006 Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders Mol Nutr Food Res 50 229 234
-
(2006)
Mol Nutr Food Res
, vol.50
, pp. 229-234
-
-
Mandel, S.1
Amit, T.2
Reznichenko, L.3
-
17
-
-
7444253369
-
Flavonoids and the brain: Interactions at the blood-brain barrier and their physiological effects on the central nervous system
-
KA Youdim B Shukitt-Hale JA Joseph 2004 Flavonoids and the brain: interactions at the blood-brain barrier and their physiological effects on the central nervous system Free Radic Biol Med 37 1683 1693
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 1683-1693
-
-
Youdim, K.A.1
Shukitt-Hale, B.2
Joseph, J.A.3
-
18
-
-
34248146970
-
Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat
-
M Mokni S Elkahoui F Limam 2007 Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat Neurochem Res 32 981 987
-
(2007)
Neurochem Res
, vol.32
, pp. 981-987
-
-
Mokni, M.1
Elkahoui, S.2
Limam, F.3
-
19
-
-
1642382889
-
Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: Implications for neurodegenerative diseases
-
S Mandel O Weinreb T Amit MB Youdim 2004 Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3- gallate: implications for neurodegenerative diseases J Neurochem 88 1555 1569
-
(2004)
J Neurochem
, vol.88
, pp. 1555-1569
-
-
Mandel, S.1
Weinreb, O.2
Amit, T.3
Youdim, M.B.4
-
20
-
-
25144482448
-
Novel mechanisms of natural antioxidant compounds in biological systems: Involvement of glutathione and glutathione-related enzymes
-
R Masella R Di Benedetto R Vari 2005 Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes J Nutr Biochem 16 577 586
-
(2005)
J Nutr Biochem
, vol.16
, pp. 577-586
-
-
Masella, R.1
Di Benedetto, R.2
Vari, R.3
-
21
-
-
10944235044
-
Anti-inflammatory plant flavonoids and cellular action mechanisms
-
HP Kim KH Son HW Chang SS Kang 2004 Anti-inflammatory plant flavonoids and cellular action mechanisms J Pharmacol Sci 96 229 245
-
(2004)
J Pharmacol Sci
, vol.96
, pp. 229-245
-
-
Kim, H.P.1
Son, K.H.2
Chang, H.W.3
Kang, S.S.4
-
22
-
-
0242662063
-
Oxyresveratrol and resveratrol are potent antioxidants and free radical scavengers: Effect on nitrosative and oxidative stress derived from microglial cells
-
P Lorenz S Roychowdhury M Engelmann 2003 Oxyresveratrol and resveratrol are potent antioxidants and free radical scavengers: effect on nitrosative and oxidative stress derived from microglial cells Nitric Oxide 9 64 76
-
(2003)
Nitric Oxide
, vol.9
, pp. 64-76
-
-
Lorenz, P.1
Roychowdhury, S.2
Engelmann, M.3
-
23
-
-
28444463999
-
The beneficial effects of fruit polyphenols on brain aging
-
Suppl 1
-
FC Lau B Shukitt-Hale JA Joseph 2005 The beneficial effects of fruit polyphenols on brain aging Neurobiol Aging 26 Suppl 1 128 132
-
(2005)
Neurobiol Aging
, vol.26
, pp. 128-132
-
-
Lau, F.C.1
Shukitt-Hale, B.2
Joseph, J.A.3
-
24
-
-
0036751978
-
A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes
-
E Esposito D Rotilio V Di Matteo 2002 A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes Neurobiol Aging 23 719 735
-
(2002)
Neurobiol Aging
, vol.23
, pp. 719-735
-
-
Esposito, E.1
Rotilio, D.2
Di Matteo, V.3
-
25
-
-
0032936755
-
Etiology and pathogenesis of Parkinson's disease
-
CW Olanow WG Tatton 1999 Etiology and pathogenesis of Parkinson's disease Annu Rev Neurosci 22 123 144
-
(1999)
Annu Rev Neurosci
, vol.22
, pp. 123-144
-
-
Olanow, C.W.1
Tatton, W.G.2
-
26
-
-
0034487963
-
Parkinson's disease as multifactorial oxidative neurodegeneration: Implications for integrative management
-
PM Kidd 2000 Parkinson's disease as multifactorial oxidative neurodegeneration: implications for integrative management Altern Med Rev 5 502 529
-
(2000)
Altern Med Rev
, vol.5
, pp. 502-529
-
-
Kidd, P.M.1
-
27
-
-
0037378026
-
Oxidative stress in Parkinson's disease
-
Suppl 3. discussion S36-S28
-
P Jenner 2003 Oxidative stress in Parkinson's disease Ann Neurol 53 Suppl 3 S26 S36 discussion S36-S28
-
(2003)
Ann Neurol
, vol.53
-
-
Jenner, P.1
-
28
-
-
34247366072
-
Inflammation as a causative factor in the aetiology of Parkinson's disease
-
PS Whitton 2007 Inflammation as a causative factor in the aetiology of Parkinson's disease Br J Pharmacol 150 963 976
-
(2007)
Br J Pharmacol
, vol.150
, pp. 963-976
-
-
Whitton, P.S.1
-
29
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
R Betarbet TB Sherer G MacKenzie 2000 Chronic systemic pesticide exposure reproduces features of Parkinson's disease Nat Neurosci 3 1301 1306
-
(2000)
Nat Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
-
30
-
-
0034637267
-
Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: Environmental risk factors for Parkinson's disease?
-
M Thiruchelvam BJ Brockel EK Richfield 2000 Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: environmental risk factors for Parkinson's disease? Brain Res 873 225 234
-
(2000)
Brain Res
, vol.873
, pp. 225-234
-
-
Thiruchelvam, M.1
Brockel, B.J.2
Richfield, E.K.3
-
31
-
-
0034671469
-
The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: Implications for Parkinson's disease
-
M Thiruchelvam EK Richfield RB Baggs 2000 The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease J Neurosci 20 9207 9214
-
(2000)
J Neurosci
, vol.20
, pp. 9207-9214
-
-
Thiruchelvam, M.1
Richfield, E.K.2
Baggs, R.B.3
-
32
-
-
34447136104
-
Resveratrol protects SH-SY5Y neuroblastoma cells from apoptosis induced by dopamine
-
MK Lee SJ Kang M Poncz 2007 Resveratrol protects SH-SY5Y neuroblastoma cells from apoptosis induced by dopamine Exp Mol Med 39 376 384
-
(2007)
Exp Mol Med
, vol.39
, pp. 376-384
-
-
Lee, M.K.1
Kang, S.J.2
Poncz, M.3
-
33
-
-
20944445992
-
Unique properties of polyphenol stilbenes in the brain: More than direct antioxidant actions; Gene/protein regulatory activity
-
S Dore 2005 Unique properties of polyphenol stilbenes in the brain: more than direct antioxidant actions; gene/protein regulatory activity Neurosignals 14 61 70
-
(2005)
Neurosignals
, vol.14
, pp. 61-70
-
-
Dore, S.1
-
34
-
-
23444445727
-
Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway
-
S Guo E Bezard B Zhao 2005 Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway Free Radic Biol Med 39 682 695
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 682-695
-
-
Guo, S.1
Bezard, E.2
Zhao, B.3
-
35
-
-
4444226105
-
Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases
-
O Weinreb S Mandel T Amit MB Youdim 2004 Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases J Nutr Biochem 15 506 516
-
(2004)
J Nutr Biochem
, vol.15
, pp. 506-516
-
-
Weinreb, O.1
Mandel, S.2
Amit, T.3
Youdim, M.B.4
-
36
-
-
33744982893
-
Etiology of Parkinson's disease
-
AH Schapira 2006 Etiology of Parkinson's disease Neurology 66 S10 S23
-
(2006)
Neurology
, vol.66
-
-
Schapira, A.H.1
-
37
-
-
34250716407
-
Mitochondrial dysfunction in Parkinson's disease
-
AH Schapira 2007 Mitochondrial dysfunction in Parkinson's disease Cell Death Differ 14 1261 1266
-
(2007)
Cell Death Differ
, vol.14
, pp. 1261-1266
-
-
Schapira, A.H.1
-
38
-
-
37049004489
-
Mitochondria in the aetiology and pathogenesis of Parkinson's disease
-
AH Schapira 2008 Mitochondria in the aetiology and pathogenesis of Parkinson's disease Lancet Neurol 7 97 109
-
(2008)
Lancet Neurol
, vol.7
, pp. 97-109
-
-
Schapira, A.H.1
-
39
-
-
33845488557
-
Nitrite and malondialdehyde content in cerebrospinal fluid of patients with Parkinson's disease
-
R Shukla M Rajani N Srivastava 2006 Nitrite and malondialdehyde content in cerebrospinal fluid of patients with Parkinson's disease Int J Neurosci 116 1391 1402
-
(2006)
Int J Neurosci
, vol.116
, pp. 1391-1402
-
-
Shukla, R.1
Rajani, M.2
Srivastava, N.3
-
42
-
-
33750465142
-
Nitric oxide synthase regulation and diversity: Implications in Parkinson's disease
-
R Kavya R Saluja S Singh M Dikshit 2006 Nitric oxide synthase regulation and diversity: implications in Parkinson's disease Nitric Oxide 15 280 294
-
(2006)
Nitric Oxide
, vol.15
, pp. 280-294
-
-
Kavya, R.1
Saluja, R.2
Singh, S.3
Dikshit, M.4
-
43
-
-
0035425503
-
Nitric oxide synthases: Structure, function and inhibition
-
WK Alderton CE Cooper RG Knowles 2001 Nitric oxide synthases: structure, function and inhibition Biochem J 357 593 615
-
(2001)
Biochem J
, vol.357
, pp. 593-615
-
-
Alderton, W.K.1
Cooper, C.E.2
Knowles, R.G.3
-
44
-
-
0039533148
-
Nitric oxide-dependent production of cGMP supports the survival of rat embryonic motor neurons cultured with brain-derived neurotrophic factor
-
AG Estevez N Spear JA Thompson 1998 Nitric oxide-dependent production of cGMP supports the survival of rat embryonic motor neurons cultured with brain-derived neurotrophic factor J Neurosci 18 3708 3714
-
(1998)
J Neurosci
, vol.18
, pp. 3708-3714
-
-
Estevez, A.G.1
Spear, N.2
Thompson, J.A.3
-
45
-
-
33745807628
-
Regulation of inducible nitric oxide synthase gene in glial cells
-
RN Saha K Pahan 2006 Regulation of inducible nitric oxide synthase gene in glial cells Antioxid Redox Signal 8 929 947
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 929-947
-
-
Saha, R.N.1
Pahan, K.2
-
46
-
-
31544458671
-
Mitochondrial NO and reactive nitrogen species production: Does mtNOS exist?
-
Z Lacza E Pankotai A Csordas 2006 Mitochondrial NO and reactive nitrogen species production: does mtNOS exist? Nitric Oxide 14 162 168
-
(2006)
Nitric Oxide
, vol.14
, pp. 162-168
-
-
Lacza, Z.1
Pankotai, E.2
Csordas, A.3
-
47
-
-
1642422748
-
Nitric oxide, complex I, and the modulation of mitochondrial reactive species in biology and disease
-
MC Carreras MC Franco JG Peralta JJ Poderoso 2004 Nitric oxide, complex I, and the modulation of mitochondrial reactive species in biology and disease Mol Aspects Med 25 125 139
-
(2004)
Mol Aspects Med
, vol.25
, pp. 125-139
-
-
Carreras, M.C.1
Franco, M.C.2
Peralta, J.G.3
Poderoso, J.J.4
-
48
-
-
33845327490
-
Nitric oxide regulation of mitochondrial oxygen consumption I: Cellular physiology
-
C Giulivi K Kato CE Cooper 2006 Nitric oxide regulation of mitochondrial oxygen consumption I: cellular physiology Am J Physiol Cell Physiol 291 C1225 C1231
-
(2006)
Am J Physiol Cell Physiol
, vol.291
-
-
Giulivi, C.1
Kato, K.2
Cooper, C.E.3
-
49
-
-
0343844458
-
Nitric oxide synthase and neuronal vulnerability in Parkinson's disease
-
S Hunot F Boissiere B Faucheux 1996 Nitric oxide synthase and neuronal vulnerability in Parkinson's disease Neuroscience 72 355 363
-
(1996)
Neuroscience
, vol.72
, pp. 355-363
-
-
Hunot, S.1
Boissiere, F.2
Faucheux, B.3
-
50
-
-
0032506608
-
Basal ganglia neuronal nitric oxide synthase mRNA expression in Parkinson's disease
-
DJ Eve AP Nisbet AE Kingsbury 1998 Basal ganglia neuronal nitric oxide synthase mRNA expression in Parkinson's disease Brain Res Mol Brain Res 63 62 71
-
(1998)
Brain Res Mol Brain Res
, vol.63
, pp. 62-71
-
-
Eve, D.J.1
Nisbet, A.P.2
Kingsbury, A.E.3
-
51
-
-
0142027661
-
Cerebral alterations in a MPTP-mouse model of Parkinson's disease-an immunocytochemical study
-
Y Muramatsu R Kurosaki H Watanabe 2003 Cerebral alterations in a MPTP-mouse model of Parkinson's disease-an immunocytochemical study J Neural Transm 110 1129 1144
-
(2003)
J Neural Transm
, vol.110
, pp. 1129-1144
-
-
Muramatsu, Y.1
Kurosaki, R.2
Watanabe, H.3
-
52
-
-
4744369832
-
Upregulation of guanylyl cyclase expression and activity in striatum of MPTP-induced parkinsonism in mice
-
M Chalimoniuk J Langfort N Lukacova J Marsala 2004 Upregulation of guanylyl cyclase expression and activity in striatum of MPTP-induced parkinsonism in mice Biochem Biophys Res Commun 324 118 126
-
(2004)
Biochem Biophys Res Commun
, vol.324
, pp. 118-126
-
-
Chalimoniuk, M.1
Langfort, J.2
Lukacova, N.3
Marsala, J.4
-
53
-
-
0033588531
-
Caspase inhibition protects nigral neurons against 6-OHDA-induced retrograde degeneration
-
B Cutillas M Espejo J Gil 1999 Caspase inhibition protects nigral neurons against 6-OHDA-induced retrograde degeneration Neuroreport 10 2605 2608
-
(1999)
Neuroreport
, vol.10
, pp. 2605-2608
-
-
Cutillas, B.1
Espejo, M.2
Gil, J.3
-
54
-
-
0028796770
-
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice
-
JB Schulz RT Matthews MM Muqit 1995 Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice J Neurochem 64 936 939
-
(1995)
J Neurochem
, vol.64
, pp. 936-939
-
-
Schulz, J.B.1
Matthews, R.T.2
Muqit, M.M.3
-
55
-
-
0029844003
-
Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons
-
P Hantraye E Brouillet R Ferrante 1996 Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons Nat Med 2 1017 1021
-
(1996)
Nat Med
, vol.2
, pp. 1017-1021
-
-
Hantraye, P.1
Brouillet, E.2
Ferrante, R.3
-
56
-
-
0031711224
-
Excitotoxicity and nitric oxide in Parkinson's disease pathogenesis
-
MF Beal 1998 Excitotoxicity and nitric oxide in Parkinson's disease pathogenesis Ann Neurol 44 S110 S114
-
(1998)
Ann Neurol
, vol.44
-
-
Beal, M.F.1
-
58
-
-
0033545925
-
Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (MPTP)-induced parkinsonism
-
AS Mandir S Przedborski V Jackson-Lewis 1999 Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism Proc Natl Acad Sci USA 96 5774 5779
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5774-5779
-
-
Mandir, A.S.1
Przedborski, S.2
Jackson-Lewis, V.3
-
59
-
-
0033521095
-
Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o′-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease
-
S Pennathur V Jackson-Lewis S Przedborski JW Heinecke 1999 Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o′-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease J Biol Chem 274 34621 34628
-
(1999)
J Biol Chem
, vol.274
, pp. 34621-34628
-
-
Pennathur, S.1
Jackson-Lewis, V.2
Przedborski, S.3
Heinecke, J.W.4
-
60
-
-
0033608739
-
Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase
-
RJ Ferrante P Hantraye E Brouillet MF Beal 1999 Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase Brain Res 823 177 182
-
(1999)
Brain Res
, vol.823
, pp. 177-182
-
-
Ferrante, R.J.1
Hantraye, P.2
Brouillet, E.3
Beal, M.F.4
-
62
-
-
0035951869
-
A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly
-
BI Giasson IV Murray JQ Trojanowski VM Lee 2001 A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly J Biol Chem 276 2380 2386
-
(2001)
J Biol Chem
, vol.276
, pp. 2380-2386
-
-
Giasson, B.I.1
Murray, I.V.2
Trojanowski, J.Q.3
Lee, V.M.4
-
63
-
-
34548313729
-
Mechanistic aspects of Parkinson's disease: Alpha-synuclein and the biomembrane
-
K Beyer 2007 Mechanistic aspects of Parkinson's disease: alpha-synuclein and the biomembrane Cell Biochem Biophys 47 285 299
-
(2007)
Cell Biochem Biophys
, vol.47
, pp. 285-299
-
-
Beyer, K.1
-
66
-
-
33745315287
-
S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
-
T Uehara T Nakamura D Yao 2006 S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration Nature 441 513 517
-
(2006)
Nature
, vol.441
, pp. 513-517
-
-
Uehara, T.1
Nakamura, T.2
Yao, D.3
-
67
-
-
34547382568
-
Inflammatory mediators leading to protein misfolding and uncompetitive/fast off-rate drug therapy for neurodegenerative disorders
-
SA Lipton Z Gu T Nakamura 2007 Inflammatory mediators leading to protein misfolding and uncompetitive/fast off-rate drug therapy for neurodegenerative disorders Int Rev Neurobiol 82 1 27
-
(2007)
Int Rev Neurobiol
, vol.82
, pp. 1-27
-
-
Lipton, S.A.1
Gu, Z.2
Nakamura, T.3
-
68
-
-
27744449782
-
S-nitrosylation in Parkinson's disease and related neurodegenerative disorders
-
KK Chung VL Dawson TM Dawson 2005 S-nitrosylation in Parkinson's disease and related neurodegenerative disorders Methods Enzymol 396 139 150
-
(2005)
Methods Enzymol
, vol.396
, pp. 139-150
-
-
Chung, K.K.1
Dawson, V.L.2
Dawson, T.M.3
-
69
-
-
2542534741
-
S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function
-
KK Chung B Thomas X Li 2004 S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function Science 304 1328 1331
-
(2004)
Science
, vol.304
, pp. 1328-1331
-
-
Chung, K.K.1
Thomas, B.2
Li, X.3
-
71
-
-
0033648514
-
Nitric oxide and cell respiration: Physiology and pathology
-
discussion 179-181
-
S Moncada 2000 Nitric oxide and cell respiration: physiology and pathology Verh K Acad Geneeskd Belg 62 171 179 discussion 179-181
-
(2000)
Verh K Acad Geneeskd Belg
, vol.62
, pp. 171-179
-
-
Moncada, S.1
-
73
-
-
9144273205
-
Differing roles of mitochondrial nitric oxide synthase in cardiomyocytes and urothelial cells
-
A Kanai M Epperly L Pearce 2004 Differing roles of mitochondrial nitric oxide synthase in cardiomyocytes and urothelial cells Am J Physiol Heart Circ Physiol 286 H13 H21
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.286
-
-
Kanai, A.1
Epperly, M.2
Pearce, L.3
-
74
-
-
38449117272
-
Mitochondria as generators and targets of nitric oxide
-
discussion 100-104
-
C Giulivi 2007 Mitochondria as generators and targets of nitric oxide Novartis Found Symp 287 92 100 discussion 100-104
-
(2007)
Novartis Found Symp
, vol.287
, pp. 92-100
-
-
Giulivi, C.1
-
75
-
-
0036470165
-
Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons
-
HM Gao JS Hong W Zhang B Liu 2002 Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons J Neurosci 22 782 790
-
(2002)
J Neurosci
, vol.22
, pp. 782-790
-
-
Gao, H.M.1
Hong, J.S.2
Zhang, W.3
Liu, B.4
-
76
-
-
0035800589
-
Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum
-
Y He S Appel W Le 2001 Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum Brain Res 909 187 193
-
(2001)
Brain Res
, vol.909
, pp. 187-193
-
-
He, Y.1
Appel, S.2
Le, W.3
-
77
-
-
84863116750
-
Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease
-
HM Gao B Liu W Zhang JS Hong 2003 Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease Faseb J 17 1954 1956
-
(2003)
Faseb J
, vol.17
, pp. 1954-1956
-
-
Gao, H.M.1
Liu, B.2
Zhang, W.3
Hong, J.S.4
-
78
-
-
34347357758
-
Inflammation in Parkinson's diseases and other neurodegenerative diseases: Cause and therapeutic implications
-
H Wilms L Zecca P Rosenstiel 2007 Inflammation in Parkinson's diseases and other neurodegenerative diseases: cause and therapeutic implications Curr Pharm Des 13 1925 1928
-
(2007)
Curr Pharm des
, vol.13
, pp. 1925-1928
-
-
Wilms, H.1
Zecca, L.2
Rosenstiel, P.3
-
79
-
-
0034520395
-
Inflammatory regulators in Parkinson's disease: INOS, lipocortin-1, and cyclooxygenases-1 and -2
-
C Knott G Stern GP Wilkin 2000 Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2 Mol Cell Neurosci 16 724 739
-
(2000)
Mol Cell Neurosci
, vol.16
, pp. 724-739
-
-
Knott, C.1
Stern, G.2
Wilkin, G.P.3
-
80
-
-
34248187134
-
Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders
-
C Mancuso G Scapagini D Curro 2007 Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders Front Biosci 12 1107 1123
-
(2007)
Front Biosci
, vol.12
, pp. 1107-1123
-
-
Mancuso, C.1
Scapagini, G.2
Curro, D.3
-
81
-
-
0032710609
-
Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
-
GT Liberatore V Jackson-Lewis S Vukosavic 1999 Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease Nat Med 5 1403 1409
-
(1999)
Nat Med
, vol.5
, pp. 1403-1409
-
-
Liberatore, G.T.1
Jackson-Lewis, V.2
Vukosavic, S.3
-
82
-
-
0042847323
-
Chronic stimulation of D1 dopamine receptors in human SK-N-MC neuroblastoma cells induces nitric-oxide synthase activation and cytotoxicity
-
J Chen C Wersinger A Sidhu 2003 Chronic stimulation of D1 dopamine receptors in human SK-N-MC neuroblastoma cells induces nitric-oxide synthase activation and cytotoxicity J Biol Chem 278 28089 28100
-
(2003)
J Biol Chem
, vol.278
, pp. 28089-28100
-
-
Chen, J.1
Wersinger, C.2
Sidhu, A.3
-
83
-
-
0025695636
-
Nitric oxide mediates iron release from ferritin
-
DW Reif RD Simmons 1990 Nitric oxide mediates iron release from ferritin Arch Biochem Biophys 283 537 541
-
(1990)
Arch Biochem Biophys
, vol.283
, pp. 537-541
-
-
Reif, D.W.1
Simmons, R.D.2
-
84
-
-
0029549375
-
Neuroprotective effects of free radical scavengers and energy repletion in animal models of neurodegenerative disease
-
discussion 116-108
-
JB Schulz MF Beal 1995 Neuroprotective effects of free radical scavengers and energy repletion in animal models of neurodegenerative disease Ann N Y Acad Sci 765 100 110 discussion 116-108
-
(1995)
Ann N Y Acad Sci
, vol.765
, pp. 100-110
-
-
Schulz, J.B.1
Beal, M.F.2
-
85
-
-
0027142518
-
Effects of dietary tea catechins on alpha-tocopherol levels, lipid peroxidation, and erythrocyte deformability in rats fed on high palm oil and perilla oil diets
-
F Nanjo M Honda K Okushio 1993 Effects of dietary tea catechins on alpha-tocopherol levels, lipid peroxidation, and erythrocyte deformability in rats fed on high palm oil and perilla oil diets Biol Pharm Bull 16 1156 1159
-
(1993)
Biol Pharm Bull
, vol.16
, pp. 1156-1159
-
-
Nanjo, F.1
Honda, M.2
Okushio, K.3
-
86
-
-
0033050624
-
ESR study on the structure-antioxidant activity relationship of tea catechins and their epimers
-
Q Guo B Zhao S Shen 1999 ESR study on the structure-antioxidant activity relationship of tea catechins and their epimers Biochim Biophys Acta 1427 13 23
-
(1999)
Biochim Biophys Acta
, vol.1427
, pp. 13-23
-
-
Guo, Q.1
Zhao, B.2
Shen, S.3
-
88
-
-
0035099168
-
Flavonoids as peroxynitrite scavengers: The role of the hydroxyl groups
-
CG Heijnen GR Haenen FA van Acker 2001 Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups Toxicol In Vitro 15 3 6
-
(2001)
Toxicol in Vitro
, vol.15
, pp. 3-6
-
-
Heijnen, C.G.1
Haenen, G.R.2
Van Acker, F.A.3
-
90
-
-
13844271390
-
Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: Investigations in primary rat mesencephalic cultures
-
LD Mercer BL Kelly MK Horne PM Beart 2005 Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary rat mesencephalic cultures Biochem Pharmacol 69 339 345
-
(2005)
Biochem Pharmacol
, vol.69
, pp. 339-345
-
-
Mercer, L.D.1
Kelly, B.L.2
Horne, M.K.3
Beart, P.M.4
-
91
-
-
12144286214
-
Nitric oxide (NO) scavenging and NO protecting effects of quercetin and their biological significance in vascular smooth muscle
-
G Lopez-Lopez L Moreno A Cogolludo 2004 Nitric oxide (NO) scavenging and NO protecting effects of quercetin and their biological significance in vascular smooth muscle Mol Pharmacol 65 851 859
-
(2004)
Mol Pharmacol
, vol.65
, pp. 851-859
-
-
Lopez-Lopez, G.1
Moreno, L.2
Cogolludo, A.3
-
92
-
-
1242331432
-
(-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors
-
T Yokozawa DY Rhyu EJ Cho 2004 (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors J Pharm Pharmacol 56 231 239
-
(2004)
J Pharm Pharmacol
, vol.56
, pp. 231-239
-
-
Yokozawa, T.1
Rhyu, D.Y.2
Cho, E.J.3
-
93
-
-
3042667647
-
Catechin polyphenols: Neurodegeneration and neuroprotection in neurodegenerative diseases
-
S Mandel MB Youdim 2004 Catechin polyphenols: neurodegeneration and neuroprotection in neurodegenerative diseases Free Radic Biol Med 37 304 317
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 304-317
-
-
Mandel, S.1
Youdim, M.B.2
-
94
-
-
33646526704
-
Neuroprotective effects of resveratrol on cerebral ischemia-induced neuron loss mediated by free radical scavenging and cerebral blood flow elevation
-
KT Lu RY Chiou LG Chen 2006 Neuroprotective effects of resveratrol on cerebral ischemia-induced neuron loss mediated by free radical scavenging and cerebral blood flow elevation J Agric Food Chem 54 3126 3131
-
(2006)
J Agric Food Chem
, vol.54
, pp. 3126-3131
-
-
Lu, K.T.1
Chiou, R.Y.2
Chen, L.G.3
-
95
-
-
34249321307
-
Neuroprotective effects of resveratrol against traumatic brain injury in immature rats
-
U Sonmez A Sonmez G Erbil 2007 Neuroprotective effects of resveratrol against traumatic brain injury in immature rats Neurosci Lett 420 133 137
-
(2007)
Neurosci Lett
, vol.420
, pp. 133-137
-
-
Sonmez, U.1
Sonmez, A.2
Erbil, G.3
-
96
-
-
0035235476
-
Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons
-
S Bastianetto WH Zheng R Quirion 2000 Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons Br J Pharmacol 131 711 720
-
(2000)
Br J Pharmacol
, vol.131
, pp. 711-720
-
-
Bastianetto, S.1
Zheng, W.H.2
Quirion, R.3
-
97
-
-
0033993607
-
Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats
-
M Virgili A Contestabile 2000 Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats Neurosci Lett 281 123 126
-
(2000)
Neurosci Lett
, vol.281
, pp. 123-126
-
-
Virgili, M.1
Contestabile, A.2
-
98
-
-
35648950008
-
2+ concentrations are involved in resveratrol protection against apoptosis in rat primary neuron cultures
-
2+ concentrations are involved in resveratrol protection against apoptosis in rat primary neuron cultures Acta Pharmacol Sin 28 1724 1730
-
(2007)
Acta Pharmacol Sin
, vol.28
, pp. 1724-1730
-
-
Gong, Q.H.1
Wang, Q.2
Shi, J.S.3
-
99
-
-
0345731023
-
Interplay of Cu, Zn superoxide dismutase and nitric oxide synthase in neurodegenerative processes
-
G Rotilio K Aquilano MR Ciriolo 2003 Interplay of Cu, Zn superoxide dismutase and nitric oxide synthase in neurodegenerative processes IUBMB Life 55 629 634
-
(2003)
IUBMB Life
, vol.55
, pp. 629-634
-
-
Rotilio, G.1
Aquilano, K.2
Ciriolo, M.R.3
-
100
-
-
34247329551
-
Mangiferin protects against 1-methyl-4-phenylpyridinium toxicity mediated by oxidative stress in N2A cells
-
L Amazzal A Lapotre F Quignon D Bagrel 2007 Mangiferin protects against 1-methyl-4-phenylpyridinium toxicity mediated by oxidative stress in N2A cells Neurosci Lett 418 159 164
-
(2007)
Neurosci Lett
, vol.418
, pp. 159-164
-
-
Amazzal, L.1
Lapotre, A.2
Quignon, F.3
Bagrel, D.4
-
101
-
-
0034758499
-
Effect of Mangifera indica L. extract (QF808) on protein and hepatic microsome peroxidation
-
G Martinez A Giuliani OS Leon 2001 Effect of Mangifera indica L. extract (QF808) on protein and hepatic microsome peroxidation Phytother Res 15 581 585
-
(2001)
Phytother Res
, vol.15
, pp. 581-585
-
-
Martinez, G.1
Giuliani, A.2
Leon, O.S.3
-
103
-
-
33744459527
-
DATS reduces LPS-induced iNOS expression, NO production, oxidative stress, and NF-kappaB activation in RAW 264.7 macrophages
-
KL Liu HW Chen RY Wang 2006 DATS reduces LPS-induced iNOS expression, NO production, oxidative stress, and NF-kappaB activation in RAW 264.7 macrophages J Agric Food Chem 54 3472 3478
-
(2006)
J Agric Food Chem
, vol.54
, pp. 3472-3478
-
-
Liu, K.L.1
Chen, H.W.2
Wang, R.Y.3
-
104
-
-
0027144465
-
Protein tyrosine kinase activation is required for lipopolysaccharide induction of cytokines in human blood monocytes
-
Y Geng B Zhang M Lotz 1993 Protein tyrosine kinase activation is required for lipopolysaccharide induction of cytokines in human blood monocytes J Immunol 151 6692 6700
-
(1993)
J Immunol
, vol.151
, pp. 6692-6700
-
-
Geng, Y.1
Zhang, B.2
Lotz, M.3
-
105
-
-
23744474477
-
Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells
-
D Kempuraj B Madhappan S Christodoulou 2005 Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells Br J Pharmacol 145 934 944
-
(2005)
Br J Pharmacol
, vol.145
, pp. 934-944
-
-
Kempuraj, D.1
Madhappan, B.2
Christodoulou, S.3
-
106
-
-
0035479909
-
Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-alpha
-
TL Wadsworth TL McDonald DR Koop 2001 Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-alpha Biochem Pharmacol 62 963 974
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 963-974
-
-
Wadsworth, T.L.1
McDonald, T.L.2
Koop, D.R.3
-
107
-
-
0019143966
-
Prostaglandin synthetase inhibition by flavonoids and phenolic compounds in relation to their O2-scavenging properties (author's transl)
-
J Baumann G Wurm F von Bruchhausen 1980 Prostaglandin synthetase inhibition by flavonoids and phenolic compounds in relation to their O2-scavenging properties (author's transl) Arch Pharm (Weinheim) 313 330 337
-
(1980)
Arch Pharm (Weinheim)
, vol.313
, pp. 330-337
-
-
Baumann, J.1
Wurm, G.2
Von Bruchhausen, F.3
-
108
-
-
0032831286
-
Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages
-
YC Liang YT Huang SH Tsai 1999 Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages Carcinogenesis 20 1945 1952
-
(1999)
Carcinogenesis
, vol.20
, pp. 1945-1952
-
-
Liang, Y.C.1
Huang, Y.T.2
Tsai, S.H.3
-
109
-
-
32144442544
-
Differential activity of kaempferol and quercetin in attenuating tumor necrosis factor receptor family signaling in bone cells
-
JL Pang DA Ricupero S Huang 2006 Differential activity of kaempferol and quercetin in attenuating tumor necrosis factor receptor family signaling in bone cells Biochem Pharmacol 71 818 826
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 818-826
-
-
Pang, J.L.1
Ricupero, D.A.2
Huang, S.3
-
110
-
-
0033766455
-
Effects of prenylated flavonoids and biflavonoids on lipopolysaccharide- induced nitric oxide production from the mouse macrophage cell line RAW 264.7
-
BS Cheon YH Kim KS Son 2000 Effects of prenylated flavonoids and biflavonoids on lipopolysaccharide-induced nitric oxide production from the mouse macrophage cell line RAW 264.7 Planta Med 66 596 600
-
(2000)
Planta Med
, vol.66
, pp. 596-600
-
-
Cheon, B.S.1
Kim, Y.H.2
Son, K.S.3
-
111
-
-
0034213030
-
Oroxylin a inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-kappaB activation
-
Y Chen L Yang TJ Lee 2000 Oroxylin A inhibition of lipopolysaccharide- induced iNOS and COX-2 gene expression via suppression of nuclear factor-kappaB activation Biochem Pharmacol 59 1445 1457
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 1445-1457
-
-
Chen, Y.1
Yang, L.2
Lee, T.J.3
-
112
-
-
0035868503
-
A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: A multiplicity of effects
-
KA Youdim JA Joseph 2001 A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects Free Radic Biol Med 30 583 594
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 583-594
-
-
Youdim, K.A.1
Joseph, J.A.2
-
113
-
-
0037115062
-
Uptake and metabolism of epicatechin and its access to the brain after oral ingestion
-
MM Abd El Mohsen G Kuhnle AR Rechner 2002 Uptake and metabolism of epicatechin and its access to the brain after oral ingestion Free Radic Biol Med 33 1693 1702
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1693-1702
-
-
Abd El Mohsen, M.M.1
Kuhnle, G.2
Rechner, A.R.3
|