-
1
-
-
84872139132
-
Strategies and techniques for multi-component drug design from medicinal herbs and traditional chinese medicine
-
Wang, Y.; Fan, X.; Qu, H.; Gao, X.; Cheng, Y. Strategies and techniques for multi-component drug design from medicinal herbs and traditional chinese medicine. Curr. Top Med. Chem. 2012, 12, 1356-1362.
-
(2012)
Curr. Top Med. Chem.
, vol.12
, pp. 1356-1362
-
-
Wang, Y.1
Fan, X.2
Qu, H.3
Gao, X.4
Cheng, Y.5
-
2
-
-
41549108420
-
From single- to multi-target drugs in cancer therapy: When aspecificity becomes an advantage
-
DOI 10.2174/092986708783503212
-
Petrelli, A.; Giordano, S. From single- to multi-target drugs in cancer therapy: When aspecificity becomes an advantage. Curr. Med. Chem. 2008, 15, 422-432. (Pubitemid 351472408)
-
(2008)
Current Medicinal Chemistry
, vol.15
, Issue.5
, pp. 422-432
-
-
Petrelli, A.1
Giordano, S.2
-
3
-
-
84865768248
-
Treatment of diabetes using traditional Chinese medicine: Past, present and future
-
Tong, X.L.; Dong, L.; Chen, L.; Zhen, Z. Treatment of diabetes using traditional Chinese medicine: Past, present and future. Am. J. Chin. Med. 2012, 40, 877-886.
-
(2012)
Am. J. Chin. Med.
, vol.40
, pp. 877-886
-
-
Tong, X.L.1
Dong, L.2
Chen, L.3
Zhen, Z.4
-
4
-
-
84862792928
-
Fighting fire with fire: Poisonous Chinese herbal medicine for cancer therapy
-
Wang, S.; Wu, X.; Tan, M.; Gong, J.; Tan, W.; Bian, B.; Chen, M.; Wang, Y. Fighting fire with fire: Poisonous Chinese herbal medicine for cancer therapy. J. Ethnopharmacol. 2012, 140, 33-45.
-
(2012)
J. Ethnopharmacol.
, vol.140
, pp. 33-45
-
-
Wang, S.1
Wu, X.2
Tan, M.3
Gong, J.4
Tan, W.5
Bian, B.6
Chen, M.7
Wang, Y.8
-
5
-
-
84860842433
-
Traditional Chinese herbal medicine and cerebral ischemia
-
Chen, Y.F. Traditional Chinese herbal medicine and cerebral ischemia. Front Biosci. (Elite Ed.) 2012, 4, 809-817.
-
(2012)
Front Biosci. (Elite Ed.)
, vol.4
, pp. 809-817
-
-
Chen, Y.F.1
-
6
-
-
79960996398
-
Chinese herbal medicines for hypercholesterolemia
-
Liu, Z.L.; Liu, J.P.; Zhang, A.L.; Wu, Q.; Ruan, Y.; Lewith, G.; Visconte, D. Chinese herbal medicines for hypercholesterolemia. Cochrane Database Syst. Rev. 2011, 7, CD008305.
-
(2011)
Cochrane Database Syst. Rev.
, vol.7
-
-
Liu, Z.L.1
Liu, J.P.2
Zhang, A.L.3
Wu, Q.4
Ruan, Y.5
Lewith, G.6
Visconte, D.7
-
7
-
-
84865249165
-
Approaches to target profiling of natural products
-
Yue, R.; Shan, L.; Yang, X.; Zhang, W. Approaches to target profiling of natural products. Curr. Med. Chem. 2012, 19, 3841-3855.
-
(2012)
Curr. Med. Chem.
, vol.19
, pp. 3841-3855
-
-
Yue, R.1
Shan, L.2
Yang, X.3
Zhang, W.4
-
8
-
-
84866461337
-
Therapeutic effects of astragaloside IV on myocardial injuries: Multi-target identification and network analysis
-
Zhao, J.; Yang, P.; Li, F.; Tao, L.; Ding, H.; Rui, Y.; Cao, Z.; Zhang, W. Therapeutic effects of astragaloside IV on myocardial injuries: Multi-target identification and network analysis. PLoS One 2012, 7, e44938.
-
(2012)
PLoS One
, vol.7
-
-
Zhao, J.1
Yang, P.2
Li, F.3
Tao, L.4
Ding, H.5
Rui, Y.6
Cao, Z.7
Zhang, W.8
-
9
-
-
79851514952
-
Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components
-
Liao, J.F.; Chiou, W.F.; Shen, Y.C.; Wang, G.J.; Chen, C.F. Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components. Chin. Med. 2011, 6, 6-13.
-
(2011)
Chin. Med.
, vol.6
, pp. 6-13
-
-
Liao, J.F.1
Chiou, W.F.2
Shen, Y.C.3
Wang, G.J.4
Chen, C.F.5
-
10
-
-
0033401423
-
A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa
-
DOI 10.1007/s000110050512
-
Moon, T.C.; Murakami, M.; Kudo, I.; Son, K.H.; Kim, H.P.; Kang, S.S.; Chang, H.W. A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa. Inflamm. Res. 1999, 48, 621-625. (Pubitemid 30017099)
-
(1999)
Inflammation Research
, vol.48
, Issue.12
, pp. 621-625
-
-
Moon, T.C.1
Murakami, M.2
Kudo, I.3
Son, K.H.4
Kim, H.P.5
Kang, S.S.6
Chang, H.W.7
-
11
-
-
33646417638
-
Anti-inflammatory principles from the fruits of Evodia rutaecarpa and their cellular action mechanisms
-
Choi, Y.H.; Shin, E.M.; Kim, Y.S.; Cai, X.F.; Lee, J.J.; Kim, H.P. Anti-inflammatory principles from the fruits of Evodia rutaecarpa and their cellular action mechanisms. Arch. Pharm. Res. 2006, 29, 293-297.
-
(2006)
Arch. Pharm. Res.
, vol.29
, pp. 293-297
-
-
Choi, Y.H.1
Shin, E.M.2
Kim, Y.S.3
Cai, X.F.4
Lee, J.J.5
Kim, H.P.6
-
12
-
-
0034815843
-
Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist
-
DOI 10.1055/s-2001-17353
-
Kobayashi, Y.; Nakano, Y.; Kizaki, M.; Hoshikuma, K.; Yokoo, Y.; Kamiya, T. Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist. Planta Med. 2001, 67, 628-633. (Pubitemid 32929573)
-
(2001)
Planta Medica
, vol.67
, Issue.7
, pp. 628-633
-
-
Kobayashi, Y.1
Nakano, Y.2
Kizaki, M.3
Hoshikuma, K.4
Yokoo, Y.5
Kamiya, T.6
-
13
-
-
0037986592
-
Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells
-
DOI 10.1111/j.1349-7006.2003.tb01358.x
-
Fei, X.F.; Wang, B.X.; Li, T.J.; Tashiro, S.; Minami, M.; Xing, D.J.; Ikejima, T. Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells. Cancer Sci. 2003, 94, 92-98. (Pubitemid 36575865)
-
(2003)
Cancer Science
, vol.94
, Issue.1
, pp. 92-98
-
-
Fei, X.F.1
Wang, B.X.2
Li, T.J.3
Tashiro, S.-I.4
Minami, M.5
Xing, D.J.6
Ikejima, T.7
-
14
-
-
0038434288
-
The nociceptive and anti-nociceptive effects of evodiamine from fruits of Evodia rutaecarpa in mice
-
DOI 10.1055/s-2003-39701
-
Kobayashi, Y. The nociceptive and anti-nociceptive effects of evodiamine from fruits of Evodia rutaecarpa in mice. Planta Med. 2003, 69, 425-428. (Pubitemid 36774182)
-
(2003)
Planta Medica
, vol.69
, Issue.5
, pp. 425-428
-
-
Kobayashi, Y.1
-
15
-
-
0026629902
-
Nitric oxide as a secretory product of mammalian cells
-
Nathan, C. Nitric oxide as a secretory product of mammalian cells. FASEB J. 1992, 6, 3051-3064.
-
(1992)
FASEB J.
, vol.6
, pp. 3051-3064
-
-
Nathan, C.1
-
16
-
-
0030855524
-
Inhibitory effect of dehydroevodiamine and evodiamine on nitric oxide production in cultured murine macrophages
-
DOI 10.1021/np960495z
-
Chiou, W.F.; Sung, Y.J.; Liao, J.F.; Shum, A.Y.; Chen, C.F. Inhibitory effect of dehydroevodiamine and evodiamine on nitric oxide production in cultured murine macrophages. J. Nat. Prod. 1997, 60, 708-711. (Pubitemid 27318419)
-
(1997)
Journal of Natural Products
, vol.60
, Issue.7
, pp. 708-711
-
-
Chiou, W.-F.1
Sung, Y.-J.2
Liao, J.-F.3
Shum, A.Y.-C.4
Chen, C.-F.5
-
17
-
-
33846031082
-
Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells
-
DOI 10.1016/j.ejphar.2006.10.002, PII S0014299906011423
-
Ko, H.C.; Wang, Y.H.; Liou, K.T.; Chen, C.M.; Chen, C.H.; Wang, W.Y.; Chang, S.; Hou, Y.C.; Chen, K.T.; Chen, C.F.; et al. Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells. Eur. J. Pharmacol. 2007, 555, 211-217. (Pubitemid 46048800)
-
(2007)
European Journal of Pharmacology
, vol.555
, Issue.2-3
, pp. 211-217
-
-
Ko, H.-C.1
Wang, Y.-H.2
Liou, K.-T.3
Chen, C.-M.4
Chen, C.-H.5
Wang, W.-Y.6
Chang, S.7
Hou, Y.-C.8
Chen, K.-T.9
Chen, C.-F.10
Shen, Y.-C.11
-
18
-
-
69549129495
-
Evodiamine represses hypoxia-induced inflammatory proteins expression and hypoxia-inducible factor 1alpha accumulation in RAW264.7
-
Liu, Y.N.; Pan, S.L.; Liao, C.H.; Huang, D.Y.; Guh, J.H.; Peng, C.Y.; Chang, Y.L.; Teng, C.M. Evodiamine represses hypoxia-induced inflammatory proteins expression and hypoxia-inducible factor 1alpha accumulation in RAW264.7. Shock 2009, 32, 263-269.
-
(2009)
Shock
, vol.32
, pp. 263-269
-
-
Liu, Y.N.1
Pan, S.L.2
Liao, C.H.3
Huang, D.Y.4
Guh, J.H.5
Peng, C.Y.6
Chang, Y.L.7
Teng, C.M.8
-
19
-
-
33751185782
-
Prostaglandin E2 receptor EP4 contributes to inflammatory pain hypersensitivity
-
Lin, C.R.; Amaya, F.; Barrett, L.; Wang, H.; Takada, J.; Samad, T.A.; Woolf, C.J. Prostaglandin E2 receptor EP4 contributes to inflammatory pain hypersensitivity. J. Pharmacol. Exp. Ther. 2006, 319, 1096-1103.
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.319
, pp. 1096-1103
-
-
Lin, C.R.1
Amaya, F.2
Barrett, L.3
Wang, H.4
Takada, J.5
Samad, T.A.6
Woolf, C.J.7
-
20
-
-
0034870541
-
Inhibitory effects of evodiamine on in vitro invasion and experimental lung metastasis of murine colon cancer cells
-
DOI 10.1248/bpb.24.917
-
Ogasawara, M.; Matsubara, T.; Suzuki, H. Inhibitory effects of evodiamine on in vitro invasion and experimental lung metastasis of murine colon cancer cells. Biol. Pharm. Bull. 2001, 24, 917-920. (Pubitemid 32750318)
-
(2001)
Biological and Pharmaceutical Bulletin
, vol.24
, Issue.8
, pp. 917-920
-
-
Ogasawara, M.1
Matsubara, T.2
Suzuki, H.3
-
21
-
-
0242275764
-
Anti-invasive and metastatic activities of evodiamine
-
DOI 10.1248/bpb.25.1491
-
Ogasawara, M.; Matsubara, T.; Takahashi, S.; Saiki, I.; Suzuki, H. Anti-invasive and metastatic activities of evodiamine. Biol. Pharm. Bull. 2002, 25, 1491-1493. (Pubitemid 39663174)
-
(2002)
Biological and Pharmaceutical Bulletin
, vol.25
, Issue.11
, pp. 1491-1493
-
-
Ogasawara, M.1
Matsunaga, T.2
Takahashi, S.3
Saiki, I.4
Suzuki, H.5
-
22
-
-
21144442212
-
Evodiamine induced human melanoma A375-S2 cell death partially through interleukin 1 mediated pathway
-
DOI 10.1248/bpb.28.984
-
Wang, C.; Wang, M.W.; Tashiro, S.; Onodera, S.; Ikejima, T. Evodiamine induced human melanoma A375-S2 cell death partially through interleukin 1 mediated pathway. Biol. Pharm. Bull. 2005, 28, 984-989. (Pubitemid 40880301)
-
(2005)
Biological and Pharmaceutical Bulletin
, vol.28
, Issue.6
, pp. 984-989
-
-
Wang, C.1
Wang, M.-W.2
Tashiro, S.-I.3
Onodera, S.4
Ikejima, T.5
-
23
-
-
33749550856
-
Caspase-dependent and caspase-independent apoptosis induced by evodiamine in human leukemic U937 cells
-
DOI 10.1158/1535-7163.MCT-06-0167
-
Lee, T.J.; Kim, E.J.; Kim, S.; Jung, E.M.; Park, J.W.; Jeong, S.H.; Park, S.E.; Yoo, Y.H.; Kwon, T.K. Caspase-dependent and caspase-independent apoptosis induced by evodiamine in human leukemic U937 cells. Mol. Cancer Ther. 2006, 5, 2398-2407. (Pubitemid 44530477)
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.9
, pp. 2398-2407
-
-
Lee, T.-J.1
Kim, E.J.2
Kim, S.3
Jung, E.M.4
Park, J.-W.5
Jeong, S.H.6
Park, S.E.7
Yoo, Y.H.8
Kwon, T.K.9
-
24
-
-
10344263866
-
Induction of mitotic arrest and apoptosis by evodiamine in human leukemic T-lymphocytes
-
Huang, Y.C.; Guh, J.H.; Teng, C.M. Induction of mitotic arrest and apoptosis by evodiamine in human leukemic T-lymphocytes. Life Sci. 2004, 75, 35-49.
-
(2004)
Life Sci.
, vol.75
, pp. 35-49
-
-
Huang, Y.C.1
Guh, J.H.2
Teng, C.M.3
-
25
-
-
34247498234
-
Anti-proliferative effects of evodiamine on human prostate cancer cell lines DU145 and PC3
-
DOI 10.1002/jcb.21036
-
Kan, S.F.; Yu, C.H.; Pu, H.F.; Hsu, J.M.; Chen, M.J.; Wang, P.S. Anti-proliferative effects of evodiamine on human prostate cancer cell lines DU145 and PC3. J. Cell. Biochem. 2007, 101, 44-56. (Pubitemid 46652571)
-
(2007)
Journal of Cellular Biochemistry
, vol.101
, Issue.1
, pp. 44-56
-
-
Kan, S.-F.1
Yu, C.-H.2
Pu, H.-F.3
Hsu, J.-M.4
Chen, M.-J.5
Wang, P.S.6
-
26
-
-
10344234253
-
Induction of mitotic arrest and apoptosis in human prostate cancer PC-3 cells by evodiamine
-
Huang, D.M.; Guh, J.H.; Huang, Y.T.; Chueh, S.C.; Chiang, P.C.; Teng, C.M. Induction of mitotic arrest and apoptosis in human prostate cancer PC-3 cells by evodiamine. J. Urol. 2005, 173, 256-261.
-
(2005)
J. Urol.
, vol.173
, pp. 256-261
-
-
Huang, D.M.1
Guh, J.H.2
Huang, Y.T.3
Chueh, S.C.4
Chiang, P.C.5
Teng, C.M.6
-
27
-
-
2942554803
-
Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP
-
DOI 10.1002/ijc.20138
-
Kang, S.F.; Huang, W.J.; Lin, L.C.; Wang, P.S. Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP. Int. J. Cancer 2004, 110, 641-651. (Pubitemid 38746021)
-
(2004)
International Journal of Cancer
, vol.110
, Issue.5
, pp. 641-651
-
-
Kan, S.-F.1
Huang, W.J.2
Lin, L.-C.3
Wang, P.S.4
-
28
-
-
19844377252
-
Antitumor mechanism of evodiamine, a constituent from Chinese herb Evodiae fructus, in human multiple-drug resistant breast cancer NCI/ADR-RES cells in vitro and in vivo
-
Liao, C.H.; Pan, S.L.; Guh, J.H.; Chang, Y.L.; Pai, H.C.; Lin, C.H.; Teng, C.M. Antitumor mechanism of evodiamine, a constituent from Chinese herb Evodiae fructus, in human multiple-drug resistant breast cancer NCI/ADR-RES cells in vitro and in vivo. Carcinogenesis 2005, 26, 968-975.
-
(2005)
Carcinogenesis
, vol.26
, pp. 968-975
-
-
Liao, C.H.1
Pan, S.L.2
Guh, J.H.3
Chang, Y.L.4
Pai, H.C.5
Lin, C.H.6
Teng, C.M.7
-
29
-
-
67249138744
-
Evodiamine: A novel anti-cancer alkaloid from Evodia rutaecarpa
-
Jiang, J.; Hu, C. Evodiamine: A novel anti-cancer alkaloid from Evodia rutaecarpa. Molecules 2009, 14, 1852-1859.
-
(2009)
Molecules
, vol.14
, pp. 1852-1859
-
-
Jiang, J.1
Hu, C.2
-
30
-
-
18244368114
-
Intracellular regulation of evodiamine-induced A375-S2 cell death
-
DOI 10.1248/bpb.26.1543
-
Zhang. Y.; Wu, L.J.; Tashiro, S.; Onodera, S.; Ikejima, T. Intracellular regulation of evodiamine-induced A375-S2 cell death. Biol. Pharm. Bull. 2003, 26, 1543-1547. (Pubitemid 41699632)
-
(2003)
Biological and Pharmaceutical Bulletin
, vol.26
, Issue.11
, pp. 1543-1547
-
-
Zhang, Y.1
Wu, L.-J.2
Tashiro, S.-I.3
Onodera, S.4
Ikejima, T.5
-
31
-
-
0347024204
-
Evodiamine induces tumor cell death through different pathways: Apoptosis and necrosis
-
Zhang. Y.; Wu, L.J.; Tashiro, S.; Onodera, S.; Ikejima, T. Evodiamine induces tumor cell death through two different pathways: Apoptosis and necrosis. Acta Pharmacol. Sin. 2004, 25, 83-89. (Pubitemid 38076083)
-
(2004)
Acta Pharmacologica Sinica
, vol.25
, Issue.1
, pp. 83-89
-
-
Zhang, Y.1
Wu, L.-J.2
Tashiro, S.-I.3
Onodera, S.4
Ikejima, T.5
-
32
-
-
0442278366
-
Atypical apoptosis in L929 cells induced by evodiamine isolated from Evodia rutaecarpa
-
DOI 10.1080/1028602031000119772
-
Zhang, Y.; Zhang, Q.H.; Wu, L.J.; Tashiro, S.; Onodera, S.; Ikejima, T. A typical apoptosis in L929 cells induced by evodiamine isolated from Evodia rutaecarpa. J. Asian Nat. Prod. Res. 2004, 6, 19-27. (Pubitemid 38190218)
-
(2004)
Journal of Asian Natural Products Research
, vol.6
, Issue.1
, pp. 19-27
-
-
Zhang, Y.1
Zhang, Q.-H.2
Wu, L.-J.3
Tashiro, S.-I.4
Onodera, S.5
Ikejima, T.6
-
33
-
-
20444504721
-
Evodiamine abolishes constitutive and inducible NF-κB activation by inhibiting IκBα kinase activation, thereby suppressing NF-κB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion
-
DOI 10.1074/jbc.M500077200
-
Takada, Y.; Kobayashi, Y.; Aggarwal, B.B. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion. J. Biol. Chem. 2005, 280, 17203-17212. (Pubitemid 41389187)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.17
, pp. 17203-17212
-
-
Takada, Y.1
Kobayashi, Y.2
Aggarwal, B.B.3
-
34
-
-
77955474313
-
Anti-proliferative effects of evodiamine on human thyroid cancer cell line ARO
-
Chen, M.C.; Yu, C.H.; Wang, S.W.; Pu, H.F.; Kan, S.F.; Lin, L.C.; Chi, C.W.; Ho, L.L.; Lee, C.H.; Wang, P.S. Anti-proliferative effects of evodiamine on human thyroid cancer cell line ARO. J. Cell. Biochem. 2010, 110, 1495-1503.
-
(2010)
J. Cell. Biochem.
, vol.110
, pp. 1495-1503
-
-
Chen, M.C.1
Yu, C.H.2
Wang, S.W.3
Pu, H.F.4
Kan, S.F.5
Lin, L.C.6
Chi, C.W.7
Ho, L.L.8
Lee, C.H.9
Wang, P.S.10
-
35
-
-
77955226921
-
Evodiamine induces caspase-dependent apoptosis and S phase arrest in human colon lovo cells
-
Zhang, C.; Fan, X.; Xu, X.; Yang, X.; Wang, X.; Liang, H.P. Evodiamine induces caspase-dependent apoptosis and S phase arrest in human colon lovo cells. Anticancer Drugs 2010, 21, 766-776.
-
(2010)
Anticancer Drugs
, vol.21
, pp. 766-776
-
-
Zhang, C.1
Fan, X.2
Xu, X.3
Yang, X.4
Wang, X.5
Liang, H.P.6
-
36
-
-
34748824207
-
Critical roles of reactive oxygen species in mitochondrial permeability transition in mediating evodiamine-induced human melanoma A375-S2 cell apoptosis
-
DOI 10.1080/10715760701499356, PII 782140378
-
Yang, J.; Wu, L.J.; Tashino, S.; Onodera, S.; Ikejima, T. Critical roles of reactive oxygen species in mitochondrial permeability transition in mediating evodiamine-induced human melanoma A375-S2 cell apoptosis. Free Radic. Res. 2007, 41, 1099-1108. (Pubitemid 47470847)
-
(2007)
Free Radical Research
, vol.41
, Issue.10
, pp. 1099-1108
-
-
Yang, J.1
Wu, L.-J.2
Tashino, S.-I.3
Onodera, S.4
Ikejima, T.5
-
37
-
-
40649127279
-
Nitric oxide activated by p38 and NF-kB facilitates apoptosis and cell cycle arrest under oxidative stress in evodiamine-treated human melanoma A375-S2 cells
-
DOI 10.1080/10715760701762407, PII 786934880
-
Yang, J.; Wu, L.J.; Tashiro, S.; Onodera, S.; Ikejima, T. Nitric oxide activated by p38 and NF-kappaB facilitates apoptosis and cell cycle arrest under oxidative stress in evodiamine-treated human melanoma A375-S2 cells. Free Radic. Res. 2008, 42, 1-11. (Pubitemid 351372186)
-
(2008)
Free Radical Research
, vol.42
, Issue.1
, pp. 1-11
-
-
Yang, J.1
Wu, L.-J.2
Tashiro, S.-I.3
Onodera, S.4
Ikejima, T.5
-
38
-
-
46649120102
-
Reactive oxygen species and nitric oxide regulate mitochondriadependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells
-
DOI 10.1080/10715760802112791, PII 793148321
-
Yang, J.; Wu, L.J.; Tashino, S.; Onodera, S.; Ikejima, T. Reactive oxygen species and nitric oxide regulate mitochondria-dependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells. Free Radic. Res. 2008, 42, 492-504. (Pubitemid 351935163)
-
(2008)
Free Radical Research
, vol.42
, Issue.5
, pp. 492-504
-
-
Yang, J.1
Wu, L.-J.2
Tashino, S.-I.3
Onodera, S.4
Ikejima, T.5
-
39
-
-
77953354020
-
Protein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma Hela cells
-
Yang, J.; Wu, L.J.; Tashino, S.; Onodera, S.; Ikejima, T. Protein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma Hela cells. Free Radic. Res. 2010, 44, 792-802.
-
(2010)
Free Radic. Res.
, vol.44
, pp. 792-802
-
-
Yang, J.1
Wu, L.J.2
Tashino, S.3
Onodera, S.4
Ikejima, T.5
-
40
-
-
77649178970
-
Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-kappaB signaling pathways and augmented by ubiquitin-proteasome inhibition
-
Wang, C.; Li, S.; Wang, M.W. Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-kappaB signaling pathways and augmented by ubiquitin-proteasome inhibition. Toxicol. In Vitro 2010, 24, 898-904.
-
(2010)
Toxicol. in Vitro
, vol.24
, pp. 898-904
-
-
Wang, C.1
Li, S.2
Wang, M.W.3
-
41
-
-
81255143133
-
Enhanced antitumor efficacy of gemcitabine by evodiamine on pancreatic cancer via regulating PI3K/Akt pathway
-
Wei, W.T.; Chen, H.; Wang, Z.H.; Ni, Z.L.; Liu, H.B.; Tong, H.F.; Guo, H.C.; Liu, D.L.; Lin, S.Z. Enhanced antitumor efficacy of gemcitabine by evodiamine on pancreatic cancer via regulating PI3K/Akt pathway. Int. J. Biol. Sci. 2012, 8, 1-14.
-
(2012)
Int. J. Biol. Sci.
, vol.8
, pp. 1-14
-
-
Wei, W.T.1
Chen, H.2
Wang, Z.H.3
Ni, Z.L.4
Liu, H.B.5
Tong, H.F.6
Guo, H.C.7
Liu, D.L.8
Lin, S.Z.9
-
42
-
-
84860394995
-
Evodiamine inhibits 12-O-tetradecanoylphorbol-13-acetate-induced activator protein 1 transactivation and cell transformation in human hepatocytes
-
Chao, D.C.; Lin, L.J.; Hsiang, C.Y.; Li, C.C.; Lo, H.Y.; Liang, J.A.; Kao, S.T.; Wu, S.L.; Ho, T.Y. Evodiamine inhibits 12-O-tetradecanoylphorbol-13- acetate-induced activator protein 1 transactivation and cell transformation in human hepatocytes. Phytother. Res. 2011, 25, 1018-1023.
-
(2011)
Phytother. Res.
, vol.25
, pp. 1018-1023
-
-
Chao, D.C.1
Lin, L.J.2
Hsiang, C.Y.3
Li, C.C.4
Lo, H.Y.5
Liang, J.A.6
Kao, S.T.7
Wu, S.L.8
Ho, T.Y.9
-
43
-
-
33645223907
-
Evodiamine inhibits in vitro angiogenesis: Implication for antitumorgenicity
-
Shyu, K.G.; Lin, S.; Lee, C.C.; Chen, E.; Lin, L.C.; Wang, B.W.; Tsai, S.C. Evodiamine inhibits in vitro angiogenesis: Implication for antitumorgenicity. Life Sci. 2006, 78, 2234-2243.
-
(2006)
Life Sci.
, vol.78
, pp. 2234-2243
-
-
Shyu, K.G.1
Lin, S.2
Lee, C.C.3
Chen, E.4
Lin, L.C.5
Wang, B.W.6
Tsai, S.C.7
-
44
-
-
16544389637
-
Inhibition by evodiamine of hepatocyte growth factor-induced invasion and migration of tumor cells
-
DOI 10.1248/bpb.27.578
-
Ogasawara, M.; Suzuki, H. Inhibition by evodiamine of hepatocyte growth factor-induced invasion and migration of tumor cells. Biol. Pharm. Bull. 2004, 27, 578-582. (Pubitemid 41701850)
-
(2004)
Biological and Pharmaceutical Bulletin
, vol.27
, Issue.4
, pp. 578-582
-
-
Ogasawara, M.1
Suzuki, H.2
-
45
-
-
84862790283
-
Evodiamine a dual catalytic inhibitor of type i and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells
-
Pan, X.; Hartley, J.M.; Hartley, J.A.; White, K.N.; Wang, Z.; Bligh, S.W. Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells. Phytomedicine 2012, 19, 618-624.
-
(2012)
Phytomedicine
, vol.19
, pp. 618-624
-
-
Pan, X.1
Hartley, J.M.2
Hartley, J.A.3
White, K.N.4
Wang, Z.5
Bligh, S.W.6
-
46
-
-
66349130754
-
Evodiamine stabilizes topoisomerase I-DNA cleavable complex to inhibit topoisomerase i activity
-
Chan, A.L.; Chang, W.S.; Chen, L.M.; Lee, C.M.; Chen, C.E.; Lin, C.M.; Hwang, J.L. Evodiamine stabilizes topoisomerase I-DNA cleavable complex to inhibit topoisomerase I activity. Molecules 2009, 14, 1342-1352.
-
(2009)
Molecules
, vol.14
, pp. 1342-1352
-
-
Chan, A.L.1
Chang, W.S.2
Chen, L.M.3
Lee, C.M.4
Chen, C.E.5
Lin, C.M.6
Hwang, J.L.7
-
47
-
-
80052937351
-
New strategies in the discovery of novel non-camptothecin topoisomerase i inhibitors
-
Sheng, C.; Miao, Z.; Zhang, W. New strategies in the discovery of novel non-camptothecin topoisomerase I inhibitors. Curr. Med. Chem. 2011, 18, 4389-4409.
-
(2011)
Curr. Med. Chem.
, vol.18
, pp. 4389-4409
-
-
Sheng, C.1
Miao, Z.2
Zhang, W.3
-
48
-
-
78149253942
-
Selection of evodiamine as a novel topoisomerase i inhibitor by structure-based virtual screening and hit optimization of evodiamine derivatives as antitumor agents
-
Dong, G.; Sheng, C.; Wang, S.; Miao, Z.; Yao, J.; Zhang, W. Selection of evodiamine as a novel topoisomerase I inhibitor by structure-based virtual screening and hit optimization of evodiamine derivatives as antitumor agents. J. Med. Chem. 2010, 53, 7521-7531.
-
(2010)
J. Med. Chem.
, vol.53
, pp. 7521-7531
-
-
Dong, G.1
Sheng, C.2
Wang, S.3
Miao, Z.4
Yao, J.5
Zhang, W.6
-
49
-
-
77950521443
-
Inhibitory effect and transcriptional impact of berberine and evodiamine on human white preadipocyte differentiation
-
Hu, Y.; Fahmy, H.; Zjawiony, J.K.; Davies, G.E. Inhibitory effect and transcriptional impact of berberine and evodiamine on human white preadipocyte differentiation. Fitoterapia 2010, 81, 259-268.
-
(2010)
Fitoterapia
, vol.81
, pp. 259-268
-
-
Hu, Y.1
Fahmy, H.2
Zjawiony, J.K.3
Davies, G.E.4
-
50
-
-
57349188918
-
Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats
-
Shi, J.; Yan, J.; Lei, Q.; Zhao, J.; Chen, K.; Yang, D.; Zhao, X.; Zhang, Y. Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats. Brain Res. 2009, 1247, 71-78.
-
(2009)
Brain Res.
, vol.1247
, pp. 71-78
-
-
Shi, J.1
Yan, J.2
Lei, Q.3
Zhao, J.4
Chen, K.5
Yang, D.6
Zhao, X.7
Zhang, Y.8
-
51
-
-
71749101583
-
Evodiamine inhibits adipogenesis via the EGFR-PKCalpha-ERK signaling pathway
-
Wang, T.; Wang, Y.; Yamashita, H. Evodiamine inhibits adipogenesis via the EGFR-PKCalpha-ERK signaling pathway. FEBS Lett. 2009, 583, 3655-3659.
-
(2009)
FEBS Lett.
, vol.583
, pp. 3655-3659
-
-
Wang, T.1
Wang, Y.2
Yamashita, H.3
-
52
-
-
37549014582
-
Evodiamine improves diet-induced obesity in a uncoupling protein-1-independent manner: Involvement of antiadipogenic mechanism and extracellularly regulated kinase/mitogen-activated protein kinase signaling
-
Wang, T.; Wang, Y.; Kontani, Y.; Kobayashi, Y.; Sato, Y.; Mori, N.; Yamashita, H. Evodiamine improves diet-induced obesity in a uncoupling protein-1-independent manner: Involvement of antiadipogenic mechanism and extracellularly regulated kinase/mitogen-activated protein kinase signaling. Endocrinology 2008, 149, 358-366.
-
(2008)
Endocrinology
, vol.149
, pp. 358-366
-
-
Wang, T.1
Wang, Y.2
Kontani, Y.3
Kobayashi, Y.4
Sato, Y.5
Mori, N.6
Yamashita, H.7
-
53
-
-
0037146890
-
Effects of evodiamine on gastrointestinal motility in male rats
-
DOI 10.1016/S0014-2999(02)02687-0, PII S0014299902026870
-
Wu, C.L.; Hung, C.R.; Chang, F.Y.; Lin, L.C.; Pau, K.Y.; Wang, P.S. Effects of evodiamine on gastrointestinal motility in male rats. Eur. J. Pharmacol. 2002, 457, 169-176. (Pubitemid 35447659)
-
(2002)
European Journal of Pharmacology
, vol.457
, Issue.2-3
, pp. 169-176
-
-
Wu, C.-L.1
Hung, C.-R.2
Chang, F.-Y.3
Lin, L.-C.4
Pau, K.-Y.F.5
Wang, P.S.6
-
54
-
-
43149087063
-
Mechanisms of disease: The role of gastrointestinal hormones in appetite and obesity
-
DOI 10.1038/ncpgasthep1118, PII NCPGASTHEP1118
-
Vincent, R.P.; Ashrafian, H.; le Roux, C.W. Mechanisms of disease: The role of gastrointestinal hormones in appetite and obesity. Nat. Clin. Pract. Gastroenterol. Hepatol. 2008, 5, 268-277. (Pubitemid 351637912)
-
(2008)
Nature Clinical Practice Gastroenterology and Hepatology
, vol.5
, Issue.5
, pp. 268-277
-
-
Vincent, R.P.1
Ashrafian, H.2
Le Roux, C.W.3
-
55
-
-
0024212744
-
Hypotensive effects of dehydroevodiamine, a quinazolinocarboline alkaloid isolated from Evodia rutaecarpa
-
Yang, H.Y.; Li, S.Y.; Chen, C.F. Hypotensive effects of dehydroevodiamine, a quinazolinocarboline alkaloid isolated from Evodia rutaecarpa. Asia Pac. J. Pharmacol. 1988, 3, 191-195.
-
(1988)
Asia Pac. J. Pharmacol.
, vol.3
, pp. 191-195
-
-
Yang, H.Y.1
Li, S.Y.2
Chen, C.F.3
-
56
-
-
0025113193
-
The hypotensive and negative chronotropic effects of dehydroevodiamine
-
DOI 10.1016/0014-2999(90)90052-8
-
Yang, M.C.; Wu, S.L.; Kao, J.S.; Chen, C.F. The hypotensive and negative chronotropic effect of dehydroevodiamine. Eur. J. Pharmacol. 1990, 182, 537-542. (Pubitemid 20260773)
-
(1990)
European Journal of Pharmacology
, vol.182
, Issue.3
, pp. 537-542
-
-
Yang, M.C.M.1
Wu, S.-L.2
Kuo, J.-S.3
Chen, C.-F.4
-
57
-
-
0026578010
-
The vasorelaxant effect of evodiamine in rat isolated mesenteric arteries: Mode of action
-
Chiou, W.F.; Chou, C.J.; Shum, A.Y.C.; Chen, C.F. The vasorelaxant effect of evodiamine in rat isolated mesenteric arteries: Mode of action. Eur. J. Pharmacol. 1992, 215, 277-283.
-
(1992)
Eur. J. Pharmacol.
, vol.215
, pp. 277-283
-
-
Chiou, W.F.1
Chou, C.J.2
Shum, A.Y.C.3
Chen, C.F.4
-
58
-
-
0030002917
-
Comparative study on vasodilatory effects of three quinazoline alkaloids isolated from Evodia rutaecarpa
-
Chiou, W.F.; Liao, J.F.; Chen, C.F. Comparative study on vasodilatory effects of three quinazoline alkaloids isolated from Evodia rutaecarpa. J. Nat. Prod. 1996, 59, 374-378.
-
(1996)
J. Nat. Prod.
, vol.59
, pp. 374-378
-
-
Chiou, W.F.1
Liao, J.F.2
Chen, C.F.3
-
59
-
-
0019814238
-
In vivo and in vitro studies on the mechanism of cardiovascular effects of Wu-Chu-Yu (Evodiae fructus)
-
Chen, C.F.; Chen, S.M.; Lin, M.T.; Chow, S.Y. In vivo and in vitro studies on the mechanism of cardiovascular effects of Wu-Chu-Yu (Evodiae fructus). Am. J. Chin. Med. 1981, 9, 39-47. (Pubitemid 12190231)
-
(1981)
American Journal of Chinese Medicine
, vol.9
, Issue.1
, pp. 39-47
-
-
Chen, C.F.1
Chen, S.M.2
Lin, M.T.3
Chow, S.Y.4
-
60
-
-
0034961783
-
Inhibitory effect of evodiamine on aldosterone release by zona glomerulosa cells in male rats
-
Hung, P.H.; Lin, L.C.; Wang, G.J.; Chen, C.F.; Wang, P.S. Inhibitory effect of evodiamine on aldosterone release by Zona glomerulosa cells in male rats. Chin. J. Physiol. 2001, 44, 53-57. (Pubitemid 32601324)
-
(2001)
Chinese Journal of Physiology
, vol.44
, Issue.2
, pp. 53-57
-
-
Hung, P.-H.1
Lin, L.-C.2
Wang, G.-J.3
Chen, C.-F.4
Wang, P.S.5
-
61
-
-
0035046155
-
The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: Possible involvement of vanilloid receptors
-
DOI 10.1055/s-2001-12008
-
Kobayashi, Y.; Hoshikuma, K.; Nakano, Y.; Yokoo, Y.; Kamiya, T. The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: Possible involvement of vanilloid receptors. Planta Med. 2001, 67, 244-248. (Pubitemid 32304195)
-
(2001)
Planta Medica
, vol.67
, Issue.3
, pp. 244-248
-
-
Kobayashi, Y.1
Hoshikuma, K.2
Nakano, Y.3
Yokoo, Y.4
Kamiya, T.5
-
62
-
-
0037355505
-
Protective effects of calcitonin gene-related peptide-mediated evodiamine on guinea-pig cardiac anaphylaxis
-
DOI 10.1007/s00210-002-0677-0
-
Rang, W.Q.; Du, Y.H.; Hu, C.P.; Ye, F.; Tan, G.S.; Deng, H.W.; Li, Y.J. Protective effects of calcitonin gene-related peptide-mediated evodiamine on guinea-pig cardiac anaphylaxis. Naunyn Schmiedebergs Arch. Pharmacol. 2003, 367, 306-311. (Pubitemid 36408013)
-
(2003)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.367
, Issue.3
, pp. 306-311
-
-
Rang, W.-Q.1
Du, Y.-H.2
Hu, C.-P.3
Ye, F.4
Tan, G.-S.5
Deng, H.-W.6
Li, Y.-J.7
-
63
-
-
11944260890
-
Protective effects of rutaecarpine in cardiac anaphylactic injury is mediated by CGRP
-
Yi, H.H.; Rang, W.Q.; Deng, P.Y.; Hu, C.P.; Liu, G.Z.; Tan, G.S.; Xu, K.P.; Li, Y.J. Protective effects of rutaecarpine in cardiac anaphylactic injury is mediated by CGRP. Planta Med. 2004, 70, 1135-1139.
-
(2004)
Planta Med.
, vol.70
, pp. 1135-1139
-
-
Yi, H.H.1
Rang, W.Q.2
Deng, P.Y.3
Hu, C.P.4
Liu, G.Z.5
Tan, G.S.6
Xu, K.P.7
Li, Y.J.8
-
64
-
-
9944239238
-
Involvement of CGRP in the inhibitory effect of rutaecarpine on vasoconstriction induced by anaphylaxis in guinea pig
-
DOI 10.1016/j.regpep.2004.08.001, PII S016701150400268X
-
Yu, J.; Tan, G.S.; Deng, P.Y.; Xu, K.P.; Hu, C.P.; Li, Y.J. Involvement of CGRP in the inhibitory effect of rutaecarpine on vasoconstriction induced by anaphylaxis in guinea pig. Regul. Pept. 2005, 125, 93-97. (Pubitemid 39593713)
-
(2005)
Regulatory Peptides
, vol.125
, Issue.1-3
, pp. 93-97
-
-
Yu, J.1
Tan, G.-S.2
Deng, P.-Y.3
Xu, K.-P.4
Hu, C.-P.5
Li, Y.-J.6
-
65
-
-
11944258043
-
Protective effects of evodiamine on myocardial ischemia-reperfusion injury in rats
-
DOI 10.1055/s-2004-835841
-
Rang, W.Q.; Du, Y.H.; Hu, C.P.; Ye, F.; Xu, K.P.; Peng, J.; Deng, H.W.; Li, Y.J. Protective effects of evodiamine on myocardial ischemia-reperfusion injury in rats. Planta Med. 2004, 70, 1140-1143. (Pubitemid 40101093)
-
(2004)
Planta Medica
, vol.70
, Issue.12
, pp. 1140-1143
-
-
Rang, W.-Q.1
Du, Y.-H.2
Hu, C.-P.3
Ye, F.4
Xu, K.-P.5
Peng, J.6
Deng, H.-W.7
Li, Y.-J.8
-
66
-
-
0036676755
-
The cardioprotection of rutaecarpine is mediated by endogenous calcitonin related-gene peptide through activation of vanilloid receptors in guinea-pig hearts
-
DOI 10.1055/s-2002-33794
-
Hu, C.P.; Xiao, L.; Deng, H.W.; Li, Y.J. The cardioprotection of rutaecarpine is mediated by endogenous calcitonin release-gene peptide through activation of vanilloid receptors in guinea-pig hearts. Planta Med. 2002, 68, 705-709. (Pubitemid 35013381)
-
(2002)
Planta Medica
, vol.68
, Issue.8
, pp. 705-709
-
-
Hu, C.-P.1
Xiao, L.2
Deng, H.-W.3
Li, Y.-J.4
-
67
-
-
66149189450
-
Evodiamine and rutaecarpine inhibit migration by LIGHT via suppression of NADPH oxidase activation
-
Heo, S.K.; Yun, H.J.; Yi, H.S.; Noh, E.K.; Park, S.D. Evodiamine and rutaecarpine inhibit migration by LIGHT via suppression of NADPH oxidase activation. J. Cell. Biochem. 2009, 107, 123-133.
-
(2009)
J. Cell. Biochem.
, vol.107
, pp. 123-133
-
-
Heo, S.K.1
Yun, H.J.2
Yi, H.S.3
Noh, E.K.4
Park, S.D.5
-
68
-
-
3943092621
-
Pathways towards and away from Alzheimer's disease
-
DOI 10.1038/nature02621
-
Mattson, M.P. Pathways towards and away from Alzheimer's disease. Nature 2004, 430, 631-639. (Pubitemid 39061671)
-
(2004)
Nature
, vol.430
, Issue.7000
, pp. 631-639
-
-
Mattson, M.P.1
-
69
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
DOI 10.1126/science.1072994
-
Hardy, J.; Selkoe, D.J. The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 2002, 297, 353-356. (Pubitemid 34790756)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
70
-
-
7044235122
-
Effects of green tea polyphenol on cognitive and acetylcholinesterase activities
-
DOI 10.1271/bbb.68.1977
-
Kim, H.K.; Kim, M.; Kim, S.; Kim, M.; Chung, J.H. Effects of green tea polyphenol on cognitive and acetylcholinesterase activities. Biosci. Biotechnol. Biochem. 2004, 68, 1977-1979. (Pubitemid 39415267)
-
(2004)
Bioscience, Biotechnology and Biochemistry
, vol.68
, Issue.9
, pp. 1977-1979
-
-
Kim, H.K.1
Kim, M.2
Kim, S.3
Kim, M.4
Chung, J.H.5
-
71
-
-
39049177580
-
Effects of green tea polyphenol on the behaviour of Alzheimer's disease like mice induced by D-galactose and Abeta25-35
-
Lu, J.H.; Guo, J.; Yang, W.H. Effects of green tea polyphenol on the behaviour of Alzheimer's disease like mice induced by D-galactose and Abeta25-35. Zhong Yao Cai 2006, 29, 352-354.
-
(2006)
Zhong Yao Cai
, vol.29
, pp. 352-354
-
-
Lu, J.H.1
Guo, J.2
Yang, W.H.3
-
72
-
-
27844497059
-
Resveratrol promotes clearance of Alzheimer's disease amyloid-β peptides
-
DOI 10.1074/jbc.M508246200
-
Marambaud, P.; Zhao, H.; Davies, P. Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J. Biol. Chem. 2005, 280, 37377-37382. (Pubitemid 41642343)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.45
, pp. 37377-37382
-
-
Marambaud, P.1
Zhao, H.2
Davies, P.3
-
73
-
-
60249098801
-
Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease
-
Karuppagounder, S.S.; Pinto, J.T.; Xu, H.; Chen, H.L.; Beal, M.F.; Gibson, G.E. Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem. Int. 2009, 54, 111-118.
-
(2009)
Neurochem. Int.
, vol.54
, pp. 111-118
-
-
Karuppagounder, S.S.1
Pinto, J.T.2
Xu, H.3
Chen, H.L.4
Beal, M.F.5
Gibson, G.E.6
-
74
-
-
48049086506
-
Protective effect of resveratrol against naphthalene-induced oxidative stress in mice
-
Sehirli, O.; Tozan, A.; Omurtag, G.Z.; Cetinel, S.; Contuk, G.; Gedik, N.; Sener, G. Protective effect of resveratrol against naphthalene-induced oxidative stress in mice. Ecotoxicol. Environ. Saf. 2008, 71, 301-308.
-
(2008)
Ecotoxicol. Environ. Saf.
, vol.71
, pp. 301-308
-
-
Sehirli, O.1
Tozan, A.2
Omurtag, G.Z.3
Cetinel, S.4
Contuk, G.5
Gedik, N.6
Sener, G.7
-
75
-
-
0028298985
-
Increased feline cerebral blood flow induced by dehydroevodiamine hydrochloride from Evodia rutaecarpa
-
Haji, A.; Momose, Y.; Takeda, R.; Nakanishi, S.; Hiriachi, T.; Arisawa, M. Increased feline cerebral blood flow induced by dehydroevodiamine hydrochloride from Evodia rutaecarpa. J. Nat. Prod. 1994, 57, 387-389. (Pubitemid 24123504)
-
(1994)
Journal of Natural Products
, vol.57
, Issue.3
, pp. 387-389
-
-
Haji, A.1
Momose, Y.2
Takeda, R.3
Nakanishi, S.4
Horiuchi, T.5
Arisawa, M.6
-
76
-
-
79952367764
-
Evodiamine improves congnitive abilities in SAMP8 and APP(swe)/PS1(ΔE9) transgenic mouse models of Alzheimer's disease
-
Yuan, S.M.; Gao, K.; Wang, D.M.; Quan, X.Z.; Liu, J.N.; Ma, C.M.; Qin, C.; Zhang, L.F. Evodiamine improves congnitive abilities in SAMP8 and APP(swe)/PS1(ΔE9) transgenic mouse models of Alzheimer's disease. Acta Pharmacol. Sin. 2011, 32, 295-302.
-
(2011)
Acta Pharmacol. Sin.
, vol.32
, pp. 295-302
-
-
Yuan, S.M.1
Gao, K.2
Wang, D.M.3
Quan, X.Z.4
Liu, J.N.5
Ma, C.M.6
Qin, C.7
Zhang, L.F.8
-
77
-
-
0029827996
-
Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa
-
DOI 10.1055/s-2006-957926
-
Park, C.H.; Kim, S.H.; Choi, W.; Lee, Y.J.; Kim, J.S.; Kang, S.S.; Suh, Y.H. Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa. Planta Med. 1996, 62, 405-409. (Pubitemid 26370329)
-
(1996)
Planta Medica
, vol.62
, Issue.5
, pp. 405-409
-
-
Park, C.H.1
Kim, S.-H.2
Choi, W.3
Lee, Y.-J.4
Kim, J.S.5
Kang, S.S.6
Suh, Y.H.7
-
78
-
-
0029044370
-
Atanine (3-dimethylallyl-4-methoxy-2-quinolone) an alkaloid with anthelmintic activity from the chinese medicinal plant evodia rutaecarpa
-
Perrett, S.; Whitfield, P.J. Atanine (3-dimethylallyl-4-methoxy-2- quinolone), an alkaloid with anthelmintic activity from the Chinese medicinal plant, Evodia rutaecarpa. Planta Med. 1995, 61, 276-278.
-
(1995)
Planta Med.
, vol.61
, pp. 276-278
-
-
Perrett, S.1
Whitfield, P.J.2
-
79
-
-
0000328667
-
Anti-Helicobacter pylori activity of quinolone alkaloids from evodiae fructus
-
Rho, T.C.; Bae, E.A.; Kim, D.H.; Oh, W.K.; Kim, B.Y.; Ahn, J.S.; Lee, H.S. Anti-Helicobacter pylori activity of quinolone alkaloids from Evodiae Fructus. Biol. Pharm. Bull. 1999, 22, 1141-1143. (Pubitemid 29507962)
-
(1999)
Biological and Pharmaceutical Bulletin
, vol.22
, Issue.10
, pp. 1141-1143
-
-
Rho, T.C.1
Bae, E.-A.2
Kim, D.-H.3
Oh, W.K.4
Kim, B.Y.5
Ahn, J.S.6
Lee, H.Y.7
-
80
-
-
0033958657
-
Highly selective antibacterial activity of novel alkyl quinolone alkaloids from a Chinese herbal medicine, Gosyuyu (Wu-Chu-Yu), against Helicobacter pylori in vitro
-
Hamasaki, N.; Ishii, E.; Tominaga, K.; Tezuka, Y.; Nagaoka, T.; Kadota, S.; Kuroki, T.; Yano, I. Highly selective antibacterial activity of novel alkyl quinolone alkaloids from a Chinese herbal medicine, Gosyuyu (Wu-Chu-Yu), against Helicobacter pylori in vitro. Microbiol. Immunol. 2000, 44, 9-15. (Pubitemid 30073693)
-
(2000)
Microbiology and Immunology
, vol.44
, Issue.1
, pp. 9-15
-
-
Hamasaki, N.1
Ishii, E.2
Tominaga, K.3
Tezuka, Y.4
Nagaoka, T.5
Kadota, S.6
Kuroki, T.7
Yano, I.8
-
81
-
-
0036800215
-
In vivo action of novel alkyl methyl quinolone alkaloids against Helicobacter pylori
-
Tominaga, K.; Higuchi, K.; Hamasaki, N.; Hamaguchi, M.; Takashima, T.; Tanigawa, T.; Watanabe, T.; Fujiwara, Y.; Tezuke, Y.; Nagaoka, T.; et al. In vivo action of novel alkyl methyl quinolone alkaloids against Helicobacter pylori. J. Antimicrob. Chemother. 2002, 50, 547-552. (Pubitemid 35214795)
-
(2002)
Journal of Antimicrobial Chemotherapy
, vol.50
, Issue.4
, pp. 547-552
-
-
Tominaga, K.1
Higuchi, K.2
Hamasaki, N.3
Hamaguchi, M.4
Takashima, T.5
Tanigawa, T.6
Watanabe, T.7
Fujiwara, Y.8
Tezuka, Y.9
Nagaoka, T.10
Kadota, S.11
Ishii, E.12
Kobayashi, K.13
Arakawa, T.14
-
82
-
-
33644845964
-
Antibacterial activity of a Chinese herb medicine, Gosyuyu (Wu-Chu-Yu), against Helicobacter pylori
-
Tominaga, K.; Higuchi, K.; Hamasaki, N.; Tanigawa, T.; Sasaki, E.; Watanabe, T.; Fujiwara, Y.; Oshitani, N.; Arakawa, T.; Ishii, E.; et al. Antibacterial activity of a Chinese herb medicine, Gosyuyu (Wu-Chu-Yu), against Helicobacter pylori. Nippon. Rinsho. 2005, 63, 592-599.
-
(2005)
Nippon. Rinsho.
, vol.63
, pp. 592-599
-
-
Tominaga, K.1
Higuchi, K.2
Hamasaki, N.3
Tanigawa, T.4
Sasaki, E.5
Watanabe, T.6
Fujiwara, Y.7
Oshitani, N.8
Arakawa, T.9
Ishii, E.10
-
83
-
-
80052685345
-
Evodia rutaecarpa and three major alkaloids abrogate influenza A virus (H1N1)-induced chemokines production and cell migration
-
Chiou, W.F.; Ko, H.C.; Wei, B.L. Evodia rutaecarpa and three major alkaloids abrogate influenza A virus (H1N1)-induced chemokines production and cell migration. Evid. Based Complement. Alternat. Med. 2011, 2011, 750513.
-
(2011)
Evid. Based Complement. Alternat. Med.
, vol.2011
, pp. 750513
-
-
Chiou, W.F.1
Ko, H.C.2
Wei, B.L.3
-
84
-
-
0034926291
-
The vanilloid receptor: A molecular gateway to the pain pathway
-
DOI 10.1146/annurev.neuro.24.1.487
-
Caterina, M.; Julius, D. The vanilloid receptor: A molecular gateway to the pain pathway. Annu. Rev. Neurosci. 2001, 24, 487-517. (Pubitemid 32695237)
-
(2001)
Annual Review of Neuroscience
, vol.24
, pp. 487-517
-
-
Caterina, M.J.1
Julius, D.2
-
85
-
-
4644282932
-
Evodiamine functions as an agonist for the vanilloid receptor TRPV1
-
Pearce, L.V.; Petukhov, P.A.; Szabo, T.; Kedei, N.; Bizik, F.; Kozikowski, A.P.; Blumberg, P.M. Evodiamine functions as an agonist for the vanilloid receptor TRPV1. Org. Biomol. Chem. 2004, 2, 2281-2286.
-
(2004)
Org. Biomol. Chem.
, vol.2
, pp. 2281-2286
-
-
Pearce, L.V.1
Petukhov, P.A.2
Szabo, T.3
Kedei, N.4
Bizik, F.5
Kozikowski, A.P.6
Blumberg, P.M.7
-
86
-
-
73449139052
-
The vanilloid receptor TRPV-1: Role in cardiovascular and gastrointestinal protection
-
Peng, L.; Li, Y.J. The vanilloid receptor TRPV-1: Role in cardiovascular and gastrointestinal protection. Eur. J. Pharmacol. 2010, 627, 1-7.
-
(2010)
Eur. J. Pharmacol.
, vol.627
, pp. 1-7
-
-
Peng, L.1
Li, Y.J.2
-
87
-
-
0030892810
-
Antinociceptive activities of 70% methanol extract of evodiae fructus (fruit of Evodia rutaecarpa var. bodinieri) and its alkaloidal components
-
Matsuda, H.; Wu, T.X.; Tanaka, T.; Linuma, M.; Kubo, M. Antinociceptive activities of 70% methanol extract of Evodiae Fructus (fruit of Evodia rutaecarpavar. bodinieri) and its alkaloidal components. Biol. Pharm. Bull. 1997, 20, 243-248. (Pubitemid 27148972)
-
(1997)
Biological and Pharmaceutical Bulletin
, vol.20
, Issue.3
, pp. 243-248
-
-
Matsuda, H.1
Wu, J.-X.2
Tanaka, T.3
Iinuma, M.4
Kubo, M.5
-
88
-
-
0025764151
-
Pharmacological properties of galenical preparation, XIV. Body temperature retaining effect of the Chinese traditional medicine, goshuyu-to and component crude drugs
-
Kano, Y.; Zong, Q.N.; Komatsu, K. Pharmacological properties of galenical preparation, XIV. Body temperature retaining effect of the Chinese traditional medicine, "goshuyu-to" and component crude drugs. Chem. Pharm. Bull. (Tokyo) 1991, 39, 690-692.
-
(1991)
Chem. Pharm. Bull. (Tokyo)
, vol.39
, pp. 690-692
-
-
Kano, Y.1
Zong, Q.N.2
Komatsu, K.3
-
89
-
-
0028842109
-
Thermoregulatory effects of alkaloids isolated from Wu-Chu-Yu in afebrile and febrile rats
-
Tsai, T.H.; Lee, T.F.; Chen, C.F.; Wang, L.C. Thermoregulatory effects of alkaloids isolated from Wu-Chu-Yu in afebrile and febrile rats. Pharmacol. Biochem. Behav. 1995, 50, 293-298.
-
(1995)
Pharmacol. Biochem. Behav.
, vol.50
, pp. 293-298
-
-
Tsai, T.H.1
Lee, T.F.2
Chen, C.F.3
Wang, L.C.4
-
90
-
-
0032715166
-
Effects of evodiamine on the secretion of testosterone in rat testicular interstitial cells
-
Lin, H.; Tsai, S.C.; Chen, J.J.; Chiao, Y.C.; Wang, S.W.; Wang, G.J.; Chen, C.F.; Wang, P.S. Effects of evodiamine on the secretion of testosterone in rat testicular interstitial cells. Metabolism 1999, 48, 1532-1535.
-
(1999)
Metabolism
, vol.48
, pp. 1532-1535
-
-
Lin, H.1
Tsai, S.C.2
Chen, J.J.3
Chiao, Y.C.4
Wang, S.W.5
Wang, G.J.6
Chen, C.F.7
Wang, P.S.8
-
91
-
-
0031196099
-
Effect of evodiamine on catecholamine secretion from bovine adrenal medulla
-
Yoshizumi, M.; Houchi, H.; Ishimura, Y.; Hirose, M.; Kitagawa, T.; Tsuchiya, K.; Minakuchi, K.; Tamaki, T. Effect of evodiamine on catecholamine secretion from bovine adrenal medulla. J. Med. Invest. 1997, 44, 79-82. (Pubitemid 127495237)
-
(1997)
Journal of Medical Investigation
, vol.44
, Issue.1-2
, pp. 79-82
-
-
Yoshizumi, M.1
Houchi, H.2
Ishimura, Y.3
Hirose, M.4
Kitagawa, T.5
Tsuchiya, K.6
Minakuchi, K.7
Tamaki, T.8
-
92
-
-
70349251216
-
Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats
-
Yu, P.L.; Chao, H.L.; Wang, S.W.; Wang, P.S. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. J. Cell. Biochem. 2009, 108, 469-475.
-
(2009)
J. Cell. Biochem.
, vol.108
, pp. 469-475
-
-
Yu, P.L.1
Chao, H.L.2
Wang, S.W.3
Wang, P.S.4
-
93
-
-
0024802401
-
Antianoxic action of evodiamine, an alkaloid in Evodia rutaecarpa fruit
-
DOI 10.1016/0378-8741(89)90090-1
-
Yamahara, J.; Yamada, T.; Kitani, T.; Naitoh, Y.; Fujimura, H. Antianoxic action of evodiamine, an alkaloid in Evodia rutaecarpa fruit. J. Ethnopharmacol. 1989, 27, 185-192. (Pubitemid 20018073)
-
(1989)
Journal of Ethnopharmacology
, vol.27
, Issue.1-2
, pp. 185-192
-
-
Yamahara, J.1
Yamada, T.2
Kitani, T.3
Naitoh, Y.4
Fujimura, H.5
-
94
-
-
33846095017
-
In vitro and in vivo antiallergic effect of the fructus of Evodia rutaecarpa and its constituents
-
DOI 10.1248/bpb.30.197
-
Shin, Y.W.; Bae, E.A.; Cai, X.F.; Lee, J.J.; Kim, D.H. In vitro and in vivo antiallergic effects on the fruits of Evodia rutaecarpa and its constituents. Biol. Pharm. Bull. 2007, 30, 197-199. (Pubitemid 46066347)
-
(2007)
Biological and Pharmaceutical Bulletin
, vol.30
, Issue.1
, pp. 197-199
-
-
Shin, Y.-W.1
Bae, E.-A.2
Cai, X.F.3
Lee, J.J.4
Kim, D.-H.5
-
95
-
-
84866739097
-
Berberine and evodiamine influence serotonin transporter (5-HTT) expression via the 5-HTT-linked polymorphic region
-
Hu, Y.; Ehli, E.A.; Hudziak, J.J.; Davies, G.E. Berberine and evodiamine influence serotonin transporter (5-HTT) expression via the 5-HTT-linked polymorphic region. Pharmacogenomics J. 2012, 12, 372-378.
-
(2012)
Pharmacogenomics J.
, vol.12
, pp. 372-378
-
-
Hu, Y.1
Ehli, E.A.2
Hudziak, J.J.3
Davies, G.E.4
-
96
-
-
0033870753
-
The bronchoconstrictive action of evodiamine, an indoloquinazoline alkaloid isolated from the fruits of evodia rutaecarpa, on guinea-pig isolated bronchus: Possible involvement on vanilloid receptors
-
DOI 10.1055/s-2000-8615
-
Kobayashi, Y.; Nakano, Y.; Hoshikuma, K.; Yokoo, Y.; Kamiya, T. The bronchoconstrictive action of evodiamine, an indoloquinazoline alkaloid isolated from the fruits of Evodia rutaecarpa, on guinea-pig isolated bronchus: Possible involvement on vanilloid receptors. Planta Med. 2000, 66, 526-530. (Pubitemid 30627540)
-
(2000)
Planta Medica
, vol.66
, Issue.6
, pp. 526-530
-
-
Kobayashi, Y.1
Nakano, Y.2
Hoshikuma, K.3
Yokoo, Y.4
Kamiya, T.5
-
97
-
-
84857406206
-
Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors
-
Guerrant, W.; Patil, V.; Canzoneri, J.C.; Oyelere, A.K. Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors. J. Med. Chem. 2012, 55, 1465-1477.
-
(2012)
J. Med. Chem.
, vol.55
, pp. 1465-1477
-
-
Guerrant, W.1
Patil, V.2
Canzoneri, J.C.3
Oyelere, A.K.4
-
98
-
-
84872187434
-
Essential role of transient receptor potential vanilloid type 1 in evodiamine-mediated protection against atherosclerosis
-
Wei, J.; Ching, L.C.; Zhao, J.F.; Shyue, S.K.; Lee, H.F.; Kou, Y.R.; Lee, T.S. Essential role of transient receptor potential vanilloid type 1 in evodiamine-mediated protection against atherosclerosis. Acta Physiol. (Oxf.) 2013, 207, 299-307.
-
(2013)
Acta Physiol. (Oxf.)
, vol.207
, pp. 299-307
-
-
Wei, J.1
Ching, L.C.2
Zhao, J.F.3
Shyue, S.K.4
Lee, H.F.5
Kou, Y.R.6
Lee, T.S.7
-
99
-
-
79959488150
-
Role of the transient receptor potential vanilloid 1 in inflammation and sepsis
-
Devesa, I.; Planells-Cases, R.; Fernández-Ballester, G.; González-Ros, J.M.; Ferrer-Montiel, A.; Fernández-Carvajal, A. Role of the transient receptor potential vanilloid 1 in inflammation and sepsis. J. Inflamm. Res. 2011, 4, 67-81.
-
(2011)
J. Inflamm. Res.
, vol.4
, pp. 67-81
-
-
Devesa, I.1
Planells-Cases, R.2
Fernández-Ballester, G.3
González-Ros, J.M.4
Ferrer-Montiel, A.5
Fernández-Carvajal, A.6
-
100
-
-
84856084105
-
Aging reverses the role of the transient receptor potential vanilloid-1 channel in systemic inflammation from anti-inflammatory to proinflammatory
-
Wanner, S.P.; Garami, A.; Pakai, E.; Oliveira, D.L.; Gavva, N.R.; Coimbra, C.C.; Romanovsky, A.A. Aging reverses the role of the transient receptor potential vanilloid-1 channel in systemic inflammation from anti-inflammatory to proinflammatory. Cell Cycle 2012, 11, 343-349.
-
(2012)
Cell Cycle
, vol.11
, pp. 343-349
-
-
Wanner, S.P.1
Garami, A.2
Pakai, E.3
Oliveira, D.L.4
Gavva, N.R.5
Coimbra, C.C.6
Romanovsky, A.A.7
-
101
-
-
84857238751
-
Transient receptor potential vanilloid type 1 and pain development
-
Palazzo, E.; Luongo, L.; de Novellis, V.; Rossi, F.; Marabese, I.; Maione, S. Transient receptor potential vanilloid type 1 and pain development. Curr. Opin. Pharmacol. 2012, 12, 9-17.
-
(2012)
Curr. Opin. Pharmacol.
, vol.12
, pp. 9-17
-
-
Palazzo, E.1
Luongo, L.2
De Novellis, V.3
Rossi, F.4
Marabese, I.5
Maione, S.6
-
102
-
-
84869882221
-
Manipulating molecular switches in brown adipocytes and their precursors: A therapeutic potential
-
Birerdinc, A.; Jarrar, M.; Stotish, T.; Randhawa, M.; Baranova, A. Manipulating molecular switches in brown adipocytes and their precursors: A therapeutic potential. Prog. Lipid Res. 2012, 52, 51-61.
-
(2012)
Prog. Lipid Res.
, vol.52
, pp. 51-61
-
-
Birerdinc, A.1
Jarrar, M.2
Stotish, T.3
Randhawa, M.4
Baranova, A.5
-
103
-
-
84857784321
-
TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice
-
Luo, Z.; Ma, L.; Zhao, Z.; He, H.; Yang, D.; Feng, X.; Ma, S.; Chen, X.; Zhu, T.; Cao, T.; et al. TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice. Cell Res. 2012, 22, 551-564.
-
(2012)
Cell Res.
, vol.22
, pp. 551-564
-
-
Luo, Z.1
Ma, L.2
Zhao, Z.3
He, H.4
Yang, D.5
Feng, X.6
Ma, S.7
Chen, X.8
Zhu, T.9
Cao, T.10
-
104
-
-
84856008563
-
TRPV1 channels regulate cortical excitability in humans
-
Mori, F.; Ribolsi, M.; Kusayanagi, H.; Monteleone, F.; Mantovani, V.; Buttari, F.; Marasco, E.; Bernardi, G.; Maccarrone, M.; Centonze, D. TRPV1 channels regulate cortical excitability in humans. J. Neurosci. 2012, 32, 873-879.
-
(2012)
J. Neurosci.
, vol.32
, pp. 873-879
-
-
Mori, F.1
Ribolsi, M.2
Kusayanagi, H.3
Monteleone, F.4
Mantovani, V.5
Buttari, F.6
Marasco, E.7
Bernardi, G.8
MacCarrone, M.9
Centonze, D.10
-
105
-
-
84862869336
-
Development of PAC-14028, a novel transient receptor potential vanilloid type 1 (TRPV1) channel antagonist as a new drug for refractory skin diseases
-
Lim, K.M.; Park, Y.H. Development of PAC-14028, a novel transient receptor potential vanilloid type 1 (TRPV1) channel antagonist as a new drug for refractory skin diseases. Arch. Pharm. Res. 2012, 35, 393-396.
-
(2012)
Arch. Pharm. Res.
, vol.35
, pp. 393-396
-
-
Lim, K.M.1
Park, Y.H.2
-
106
-
-
84874637703
-
Antioncogenic effects of transient receptor potential vanilloid 1 in the progression of transitional urothelial cancer of human bladder
-
Santoni, G.; Caprodossi, S.; Farfariello, V.; Liberati, S.; Gismondi, A.; Amantini, C. Antioncogenic effects of transient receptor potential vanilloid 1 in the progression of transitional urothelial cancer of human bladder. ISRN Urol. 2012, 2012, 458238.
-
(2012)
ISRN Urol.
, vol.2012
, pp. 458238
-
-
Santoni, G.1
Caprodossi, S.2
Farfariello, V.3
Liberati, S.4
Gismondi, A.5
Amantini, C.6
-
107
-
-
84864369512
-
Binding mode prediction of evodiamine within vanilloid receptor TRPV1
-
Wang, Z.; Sun, L.; Yu, H.; Zhang, Y.; Gong, W.; Jin, H.; Zhang, L.; Liang, H. Binding mode prediction of evodiamine within vanilloid receptor TRPV1. Int. J. Mol. Sci. 2012, 13, 8958-8969.
-
(2012)
Int. J. Mol. Sci.
, vol.13
, pp. 8958-8969
-
-
Wang, Z.1
Sun, L.2
Yu, H.3
Zhang, Y.4
Gong, W.5
Jin, H.6
Zhang, L.7
Liang, H.8
-
108
-
-
84864395482
-
DNA-topoisomerases and their functions in cell
-
Giliarov, D.A.; Shkundina, I.S. DNA-topoisomerases and their functions in cell. Mol. Biol. (Mosk.) 2012, 46, 52-63.
-
(2012)
Mol. Biol. (Mosk.)
, vol.46
, pp. 52-63
-
-
Giliarov, D.A.1
Shkundina, I.S.2
-
109
-
-
84861485138
-
QSAR modeling on benzo[c]phenanthridine analogues as topoisomerase i inhibitors and anti-cancer agents
-
Thai, K.M.; Bui, Q.H.; Tran, T.D.; Huynh, T.N. QSAR modeling on benzo[c]phenanthridine analogues as topoisomerase I inhibitors and anti-cancer agents. Molecules 2012, 17, 5690-5712.
-
(2012)
Molecules
, vol.17
, pp. 5690-5712
-
-
Thai, K.M.1
Bui, Q.H.2
Tran, T.D.3
Huynh, T.N.4
-
110
-
-
84857239566
-
Dihydroxylated 2,4,6-triphenyl pyridines: Synthesis, topoisomerase i and II inhibitory activity, cytotoxicity, and structure-activity relationship study
-
Karki, R.; Thapa, P.; Yoo, H.Y.; Kadayat, T.M.; Park, P.H.; Na, Y.; Lee, E.; Jeon, K.H.; Cho, W.J.; Choi, H.; et al. Dihydroxylated 2,4,6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study. Eur. J. Med. Chem. 2012, 49, 219-228.
-
(2012)
Eur. J. Med. Chem.
, vol.49
, pp. 219-228
-
-
Karki, R.1
Thapa, P.2
Yoo, H.Y.3
Kadayat, T.M.4
Park, P.H.5
Na, Y.6
Lee, E.7
Jeon, K.H.8
Cho, W.J.9
Choi, H.10
-
111
-
-
84862809544
-
Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles
-
Lee, C.H.; Hsieh, M.Y.; Hsin, L.W.; Chen, H.C.; Lo, S.C.; Fan, J.R.; Chen, W.R.; Chen, H.W.; Chan, N.L.; Li, T.K. Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles. Biochem. Pharmacol. 2012, 83, 1208-1216.
-
(2012)
Biochem. Pharmacol.
, vol.83
, pp. 1208-1216
-
-
Lee, C.H.1
Hsieh, M.Y.2
Hsin, L.W.3
Chen, H.C.4
Lo, S.C.5
Fan, J.R.6
Chen, W.R.7
Chen, H.W.8
Chan, N.L.9
Li, T.K.10
-
112
-
-
84859364840
-
Bacterial DNA replication enzymes as targets for antibacterial drug discovery
-
Sanyal, G.; Doig, P. Bacterial DNA replication enzymes as targets for antibacterial drug discovery. Expert Opin. Drug Discov. 2012, 7, 327-339.
-
(2012)
Expert Opin. Drug Discov.
, vol.7
, pp. 327-339
-
-
Sanyal, G.1
Doig, P.2
-
113
-
-
84858714296
-
Synthesis and structure-activity relationships of new quinolone-type molecules against Trypanosoma brucei
-
Hiltensperger, G.; Jones, N.G.; Niedermeier, S.; Stich, A.; Kaiser, M.; Jung, J.; Puhl, S.; Damme, A.; Braunschweig, H.; Meinel, L.; et al. Synthesis and structure-activity relationships of new quinolone-type molecules against Trypanosoma brucei. J. Med. Chem. 2012, 55, 2538-2548.
-
(2012)
J. Med. Chem.
, vol.55
, pp. 2538-2548
-
-
Hiltensperger, G.1
Jones, N.G.2
Niedermeier, S.3
Stich, A.4
Kaiser, M.5
Jung, J.6
Puhl, S.7
Damme, A.8
Braunschweig, H.9
Meinel, L.10
-
114
-
-
57449120634
-
Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy
-
Martin, E.; Thougaard, A.V.; Grauslund, M.; Jensen, P.B.; Bjorkling, F.; Hasinoff, B.B.; Tjørnelund, J.; Sehested, M.; Jensen, L.H. Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy. Toxicology 2009, 255, 72-79.
-
(2009)
Toxicology
, vol.255
, pp. 72-79
-
-
Martin, E.1
Thougaard, A.V.2
Grauslund, M.3
Jensen, P.B.4
Bjorkling, F.5
Hasinoff, B.B.6
Tjørnelund, J.7
Sehested, M.8
Jensen, L.H.9
-
115
-
-
84860717980
-
Topoisomerase IIβ regulates base excision repair capacity of neurons
-
Gupta, K.P.; Swain, U.; Rao, K.S.; Kondapi, A.K. Topoisomerase IIβ regulates base excision repair capacity of neurons. Mech. Ageing Dev. 2012, 133, 203-213.
-
(2012)
Mech. Ageing Dev.
, vol.133
, pp. 203-213
-
-
Gupta, K.P.1
Swain, U.2
Rao, K.S.3
Kondapi, A.K.4
-
116
-
-
0026725943
-
Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor
-
Burbach, K.M.; Poland, A.; Bradfield, C.A. Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proc. Natl. Acad. Sci. USA 1992, 89, 8185-8189.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 8185-8189
-
-
Burbach, K.M.1
Poland, A.2
Bradfield, C.A.3
-
117
-
-
0023742858
-
Association of the Ah receptor with the 90-kDa heat shock protein
-
Perdew, G.H. Association of the Ah receptor with the 90-kDa heat shock protein. J. Biol. Chem. 1988, 263, 13802-13805.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 13802-13805
-
-
Perdew, G.H.1
-
118
-
-
0033531928
-
Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (Aryl hydrocarbon) receptor
-
Kazlauskas, A.; Poellinger, L.; Pongratz, I. Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (Aryl hydrocarbon) receptor. J. Biol. Chem. 1999, 274, 13519-13524.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13519-13524
-
-
Kazlauskas, A.1
Poellinger, L.2
Pongratz, I.3
-
119
-
-
0031882767
-
Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity
-
Meyer, B.K.; Pray-Grant, M.G.; Vanden Heuvel, J.P.; Perdew, G.H. Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity. Mol. Cell. Biol. 1998, 18, 978-988. (Pubitemid 28063432)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.2
, pp. 978-988
-
-
Meyer, B.K.1
Pray-Grant, M.G.2
Vanden Heuvel, J.P.3
Perdew, G.H.4
-
120
-
-
0033861976
-
Analysis of the complex relationship between nuclear export and aryl hydrocarbon receptor-mediated gene regulation
-
DOI 10.1128/MCB.20.16.6095-6104.2000
-
Pollenz, R.S.; Barbour, E.R. Analysis of the complex relationship between nuclear export and aryl hydrocarbon receptor-mediated gene regulation. Mol. Cell. Biol. 2000, 20, 6095-6104. (Pubitemid 30613057)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.16
, pp. 6095-6104
-
-
Pollenz, R.S.1
Barbour, E.R.2
-
121
-
-
0025906014
-
Cloning of a factor required for activity of the Ah (dioxin) receptor
-
Hoffman, E.C.; Reyes, H.; Chu, F.F.; Sander, F.; Conley, L.H.; Brooks, B.A.; Hankinson, O. Cloning of a factor required for activity of the Ah (dioxin) receptor. Science 1991, 252, 954-958. (Pubitemid 21917012)
-
(1991)
Science
, vol.252
, Issue.5008
, pp. 954-958
-
-
Hoffman, E.C.1
Reyes, H.2
Chu, F.-F.3
Sander, F.4
Conley, L.H.5
Brooks, B.A.6
Hankinson, O.7
-
122
-
-
0026625037
-
Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor
-
Reyes, H.; Reisz-Porszasz, S.; Hankinson, O. Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor. Science 1992, 256, 1193-1195.
-
(1992)
Science
, vol.256
, pp. 1193-1195
-
-
Reyes, H.1
Reisz-Porszasz, S.2
Hankinson, O.3
-
123
-
-
30044452058
-
Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries
-
DOI 10.1124/mol.105.018705
-
Tijet, N.; Boutros, P.C.; Moffat, I.D.; Okey, A.B.; Tuomisto, J.; Pohjanvirta, R. Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries. Mol. Pharmacol. 2006, 69, 140-153. (Pubitemid 43048901)
-
(2006)
Molecular Pharmacology
, vol.69
, Issue.1
, pp. 140-153
-
-
Tijet, N.1
Boutros, P.C.2
Moffat, I.D.3
Okey, A.B.4
Tuomisto, J.5
Pohjanvirta, R.6
-
124
-
-
0021060932
-
1-450 in wild type and variant mouse hepatoma cells
-
Israel, D.I.; Whitlock, J.P. Induction of mRNA specific for cytochrome P1-450 in wild type and variant mouse hepatoma cells. J. Biol. Chem. 1983, 258, 10390-10394. (Pubitemid 14241199)
-
(1983)
Journal of Biological Chemistry
, vol.258
, Issue.17
, pp. 10390-10394
-
-
Israel, D.I.1
Whitlock Jr., J.P.2
-
125
-
-
1342310142
-
DNA adduct formation in precision-cut rat liver and lung slices exposed to Benzo[a]pyrene
-
DOI 10.1093/toxsci/kfh030
-
Harrigan, J.A.; Vezina, C.M.; McGarrigle, B.P.; Ersing, N.; Box, H.C.; Maccubbin, A.E.; Olson, J.R. DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene. Toxicol. Sci. 2004, 77, 307-314. (Pubitemid 38262604)
-
(2004)
Toxicological Sciences
, vol.77
, Issue.2
, pp. 307-314
-
-
Harrigan, J.A.1
Vezina, C.M.2
McGarrigle, B.P.3
Ersing, N.4
Box, H.C.5
Maccubbin, A.E.6
Olson, J.R.7
-
126
-
-
84866077937
-
SU5416, a VEGF receptor inhibitor and ligand of the AhR, represents a new alternative for immunomodulation
-
Mezrich, J.D.; Nguyen, L.P.; Kennedy, G.; Nukaya, M.; Fechner, J.H.; Zhang, X.; Xing, Y.; Bradfield, C.A. SU5416, a VEGF receptor inhibitor and ligand of the AhR, represents a new alternative for immunomodulation. PLoS One 2012, 7, e44547.
-
(2012)
PLoS One
, vol.7
-
-
Mezrich, J.D.1
Nguyen, L.P.2
Kennedy, G.3
Nukaya, M.4
Fechner, J.H.5
Zhang, X.6
Xing, Y.7
Bradfield, C.A.8
-
127
-
-
84868117782
-
Aryl hydrocarbon receptor-dependence of dioxin's effects on constitutive mouse hepatic cytochromes P450 and growth hormone signaling components
-
Lee, C.; Riddick, D.S. Aryl hydrocarbon receptor-dependence of dioxin's effects on constitutive mouse hepatic cytochromes P450 and growth hormone signaling components. Can. J. Physiol. Pharmacol. 2012, 90, 1354-1363.
-
(2012)
Can. J. Physiol. Pharmacol.
, vol.90
, pp. 1354-1363
-
-
Lee, C.1
Riddick, D.S.2
-
128
-
-
84863990840
-
The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells
-
O'Donnell, E.F.; Kopparapu, P.R.; Koch, D.C.; Jang, H.S.; Phillips, J.L.; Tanguay, R.L.; Kerkvliet, N.I.; Kolluri, S.K. The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells. PLoS One 2012, 7, e40926.
-
(2012)
PLoS One
, vol.7
-
-
O'Donnell, E.F.1
Kopparapu, P.R.2
Koch, D.C.3
Jang, H.S.4
Phillips, J.L.5
Tanguay, R.L.6
Kerkvliet, N.I.7
Kolluri, S.K.8
-
129
-
-
84874594968
-
The aryl hydrocarbon receptor in tumor immunity
-
Platten, M.; Litzenburger, U.; Wick, W. The aryl hydrocarbon receptor in tumor immunity. Oncoimmunology 2012, 1, 396-397.
-
(2012)
Oncoimmunology
, vol.1
, pp. 396-397
-
-
Platten, M.1
Litzenburger, U.2
Wick, W.3
-
130
-
-
79959918506
-
Aryl hydrocarbon receptor-induced signals up-regulate IL-22 production and inhibit inflammation in the gastrointestinal tract
-
Monteleone, I.; Rizzo, A.; Sarra, M.; Sica, G.; Sileri, P.; Biancone, L.; MacDonald, T.T.; Pallone, F.; Monteleone, G. Aryl hydrocarbon receptor-induced signals up-regulate IL-22 production and inhibit inflammation in the gastrointestinal tract. Gastroenterology 2011, 141, 237-248.
-
(2011)
Gastroenterology
, vol.141
, pp. 237-248
-
-
Monteleone, I.1
Rizzo, A.2
Sarra, M.3
Sica, G.4
Sileri, P.5
Biancone, L.6
MacDonald, T.T.7
Pallone, F.8
Monteleone, G.9
-
131
-
-
78049278823
-
Evodiamine as a novel antagonist of aryl hydrocarbon receptor
-
Yu, H.; Tu,Y.; Zhang, C.; Fan, X.; Wang, X.; Wang, Z.; Liang, H. Evodiamine as a novel antagonist of aryl hydrocarbon receptor. Biochem. Biophys. Res. Commun. 2010, 402, 94-98.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.402
, pp. 94-98
-
-
Yu, H.1
Tu, Y.2
Zhang, C.3
Fan, X.4
Wang, X.5
Wang, Z.6
Liang, H.7
-
132
-
-
84863284796
-
Preparation of evodiamine solid dispersions and its pharmacokinetics
-
Xu, H.; Zhang, T.; Yang, H.; Xiao, X.; Bian, Y.; Si, D.; Liu, C. Preparation of evodiamine solid dispersions and its pharmacokinetics. Indian J. Pharm. Sci. 2011, 73, 276-281.
-
(2011)
Indian J. Pharm. Sci.
, vol.73
, pp. 276-281
-
-
Xu, H.1
Zhang, T.2
Yang, H.3
Xiao, X.4
Bian, Y.5
Si, D.6
Liu, C.7
-
133
-
-
84862877338
-
Design and evaluation of a novel evodiamine-phospholipid complex for improved oral bioavailability
-
Tan, Q.; Liu, S.; Chen, X.; Wu, M.; Wang, H.; Yin, H.; He, D.; Xiong, H.; Zhang, J. Design and evaluation of a novel evodiamine-phospholipid complex for improved oral bioavailability. AAPS PharmSciTech. 2012, 13, 534-547.
-
(2012)
AAPS PharmSciTech.
, vol.13
, pp. 534-547
-
-
Tan, Q.1
Liu, S.2
Chen, X.3
Wu, M.4
Wang, H.5
Yin, H.6
He, D.7
Xiong, H.8
Zhang, J.9
-
134
-
-
0027501222
-
Pharmacological properties of galenical preparation. XVI. Pharmacokinetics of evodiamine and the metabolite in rats
-
Komatsu, K.; Wakame, K.; Kano, Y. Pharmacological properties of galenical preparation. XVI. Pharmacokinetics of evodiamine and the metabolite in rats. Biol. Pharm. Bull. 1993, 16, 935-938. (Pubitemid 23329810)
-
(1993)
Biological and Pharmaceutical Bulletin
, vol.16
, Issue.9
, pp. 935-938
-
-
Komatsu, K.-I.1
Wakame, K.2
Kano, Y.3
-
135
-
-
0029015253
-
High-performance liquid chromatographic determination of evodiamine in rat plasma: Application to pharmacokinetic studies
-
Jeng, K.F.; Lin, Y.H.; Lin, L.C.; Chou, C.J.; Tsai, T.H.; Chen, C.F. High-performance liquid chromatographic determination of evodiamine in rat plasma: Application to pharmacokinetic studies. J. Chromatogr. B Biomed. Appl. 1995, 668, 343-345.
-
(1995)
J. Chromatogr. B Biomed. Appl.
, vol.668
, pp. 343-345
-
-
Jeng, K.F.1
Lin, Y.H.2
Lin, L.C.3
Chou, C.J.4
Tsai, T.H.5
Chen, C.F.6
-
136
-
-
84862922006
-
Simultaneous determination of evodiamine and rutecarpine in rabbit plasma by LC-ESI-MS and its application to pharmacokinetics
-
Lin, C.; Pan, X.; Li, W.; Ma, J.; Pan, J.; Cai, J.; Wang, X.; Lin, G. Simultaneous determination of evodiamine and rutecarpine in rabbit plasma by LC-ESI-MS and its application to pharmacokinetics. Pharmazie 2011, 66, 920-923.
-
(2011)
Pharmazie
, vol.66
, pp. 920-923
-
-
Lin, C.1
Pan, X.2
Li, W.3
Ma, J.4
Pan, J.5
Cai, J.6
Wang, X.7
Lin, G.8
|