메뉴 건너뛰기




Volumn 18, Issue 2, 2013, Pages 1826-1843

Pharmacological actions of multi-target-directed evodiamine

Author keywords

Bioactivity; Evodiamine; Mechanism; Receptor binding

Indexed keywords

EVODIAMINE; LIGAND; PROTEIN; QUINAZOLINE DERIVATIVE;

EID: 84874609274     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules18021826     Document Type: Review
Times cited : (155)

References (136)
  • 1
    • 84872139132 scopus 로고    scopus 로고
    • Strategies and techniques for multi-component drug design from medicinal herbs and traditional chinese medicine
    • Wang, Y.; Fan, X.; Qu, H.; Gao, X.; Cheng, Y. Strategies and techniques for multi-component drug design from medicinal herbs and traditional chinese medicine. Curr. Top Med. Chem. 2012, 12, 1356-1362.
    • (2012) Curr. Top Med. Chem. , vol.12 , pp. 1356-1362
    • Wang, Y.1    Fan, X.2    Qu, H.3    Gao, X.4    Cheng, Y.5
  • 2
    • 41549108420 scopus 로고    scopus 로고
    • From single- to multi-target drugs in cancer therapy: When aspecificity becomes an advantage
    • DOI 10.2174/092986708783503212
    • Petrelli, A.; Giordano, S. From single- to multi-target drugs in cancer therapy: When aspecificity becomes an advantage. Curr. Med. Chem. 2008, 15, 422-432. (Pubitemid 351472408)
    • (2008) Current Medicinal Chemistry , vol.15 , Issue.5 , pp. 422-432
    • Petrelli, A.1    Giordano, S.2
  • 3
    • 84865768248 scopus 로고    scopus 로고
    • Treatment of diabetes using traditional Chinese medicine: Past, present and future
    • Tong, X.L.; Dong, L.; Chen, L.; Zhen, Z. Treatment of diabetes using traditional Chinese medicine: Past, present and future. Am. J. Chin. Med. 2012, 40, 877-886.
    • (2012) Am. J. Chin. Med. , vol.40 , pp. 877-886
    • Tong, X.L.1    Dong, L.2    Chen, L.3    Zhen, Z.4
  • 4
    • 84862792928 scopus 로고    scopus 로고
    • Fighting fire with fire: Poisonous Chinese herbal medicine for cancer therapy
    • Wang, S.; Wu, X.; Tan, M.; Gong, J.; Tan, W.; Bian, B.; Chen, M.; Wang, Y. Fighting fire with fire: Poisonous Chinese herbal medicine for cancer therapy. J. Ethnopharmacol. 2012, 140, 33-45.
    • (2012) J. Ethnopharmacol. , vol.140 , pp. 33-45
    • Wang, S.1    Wu, X.2    Tan, M.3    Gong, J.4    Tan, W.5    Bian, B.6    Chen, M.7    Wang, Y.8
  • 5
    • 84860842433 scopus 로고    scopus 로고
    • Traditional Chinese herbal medicine and cerebral ischemia
    • Chen, Y.F. Traditional Chinese herbal medicine and cerebral ischemia. Front Biosci. (Elite Ed.) 2012, 4, 809-817.
    • (2012) Front Biosci. (Elite Ed.) , vol.4 , pp. 809-817
    • Chen, Y.F.1
  • 7
    • 84865249165 scopus 로고    scopus 로고
    • Approaches to target profiling of natural products
    • Yue, R.; Shan, L.; Yang, X.; Zhang, W. Approaches to target profiling of natural products. Curr. Med. Chem. 2012, 19, 3841-3855.
    • (2012) Curr. Med. Chem. , vol.19 , pp. 3841-3855
    • Yue, R.1    Shan, L.2    Yang, X.3    Zhang, W.4
  • 8
    • 84866461337 scopus 로고    scopus 로고
    • Therapeutic effects of astragaloside IV on myocardial injuries: Multi-target identification and network analysis
    • Zhao, J.; Yang, P.; Li, F.; Tao, L.; Ding, H.; Rui, Y.; Cao, Z.; Zhang, W. Therapeutic effects of astragaloside IV on myocardial injuries: Multi-target identification and network analysis. PLoS One 2012, 7, e44938.
    • (2012) PLoS One , vol.7
    • Zhao, J.1    Yang, P.2    Li, F.3    Tao, L.4    Ding, H.5    Rui, Y.6    Cao, Z.7    Zhang, W.8
  • 9
    • 79851514952 scopus 로고    scopus 로고
    • Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components
    • Liao, J.F.; Chiou, W.F.; Shen, Y.C.; Wang, G.J.; Chen, C.F. Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components. Chin. Med. 2011, 6, 6-13.
    • (2011) Chin. Med. , vol.6 , pp. 6-13
    • Liao, J.F.1    Chiou, W.F.2    Shen, Y.C.3    Wang, G.J.4    Chen, C.F.5
  • 10
  • 11
    • 33646417638 scopus 로고    scopus 로고
    • Anti-inflammatory principles from the fruits of Evodia rutaecarpa and their cellular action mechanisms
    • Choi, Y.H.; Shin, E.M.; Kim, Y.S.; Cai, X.F.; Lee, J.J.; Kim, H.P. Anti-inflammatory principles from the fruits of Evodia rutaecarpa and their cellular action mechanisms. Arch. Pharm. Res. 2006, 29, 293-297.
    • (2006) Arch. Pharm. Res. , vol.29 , pp. 293-297
    • Choi, Y.H.1    Shin, E.M.2    Kim, Y.S.3    Cai, X.F.4    Lee, J.J.5    Kim, H.P.6
  • 12
    • 0034815843 scopus 로고    scopus 로고
    • Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist
    • DOI 10.1055/s-2001-17353
    • Kobayashi, Y.; Nakano, Y.; Kizaki, M.; Hoshikuma, K.; Yokoo, Y.; Kamiya, T. Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist. Planta Med. 2001, 67, 628-633. (Pubitemid 32929573)
    • (2001) Planta Medica , vol.67 , Issue.7 , pp. 628-633
    • Kobayashi, Y.1    Nakano, Y.2    Kizaki, M.3    Hoshikuma, K.4    Yokoo, Y.5    Kamiya, T.6
  • 13
    • 0037986592 scopus 로고    scopus 로고
    • Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells
    • DOI 10.1111/j.1349-7006.2003.tb01358.x
    • Fei, X.F.; Wang, B.X.; Li, T.J.; Tashiro, S.; Minami, M.; Xing, D.J.; Ikejima, T. Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells. Cancer Sci. 2003, 94, 92-98. (Pubitemid 36575865)
    • (2003) Cancer Science , vol.94 , Issue.1 , pp. 92-98
    • Fei, X.F.1    Wang, B.X.2    Li, T.J.3    Tashiro, S.-I.4    Minami, M.5    Xing, D.J.6    Ikejima, T.7
  • 14
    • 0038434288 scopus 로고    scopus 로고
    • The nociceptive and anti-nociceptive effects of evodiamine from fruits of Evodia rutaecarpa in mice
    • DOI 10.1055/s-2003-39701
    • Kobayashi, Y. The nociceptive and anti-nociceptive effects of evodiamine from fruits of Evodia rutaecarpa in mice. Planta Med. 2003, 69, 425-428. (Pubitemid 36774182)
    • (2003) Planta Medica , vol.69 , Issue.5 , pp. 425-428
    • Kobayashi, Y.1
  • 15
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan, C. Nitric oxide as a secretory product of mammalian cells. FASEB J. 1992, 6, 3051-3064.
    • (1992) FASEB J. , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 16
    • 0030855524 scopus 로고    scopus 로고
    • Inhibitory effect of dehydroevodiamine and evodiamine on nitric oxide production in cultured murine macrophages
    • DOI 10.1021/np960495z
    • Chiou, W.F.; Sung, Y.J.; Liao, J.F.; Shum, A.Y.; Chen, C.F. Inhibitory effect of dehydroevodiamine and evodiamine on nitric oxide production in cultured murine macrophages. J. Nat. Prod. 1997, 60, 708-711. (Pubitemid 27318419)
    • (1997) Journal of Natural Products , vol.60 , Issue.7 , pp. 708-711
    • Chiou, W.-F.1    Sung, Y.-J.2    Liao, J.-F.3    Shum, A.Y.-C.4    Chen, C.-F.5
  • 17
    • 33846031082 scopus 로고    scopus 로고
    • Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells
    • DOI 10.1016/j.ejphar.2006.10.002, PII S0014299906011423
    • Ko, H.C.; Wang, Y.H.; Liou, K.T.; Chen, C.M.; Chen, C.H.; Wang, W.Y.; Chang, S.; Hou, Y.C.; Chen, K.T.; Chen, C.F.; et al. Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells. Eur. J. Pharmacol. 2007, 555, 211-217. (Pubitemid 46048800)
    • (2007) European Journal of Pharmacology , vol.555 , Issue.2-3 , pp. 211-217
    • Ko, H.-C.1    Wang, Y.-H.2    Liou, K.-T.3    Chen, C.-M.4    Chen, C.-H.5    Wang, W.-Y.6    Chang, S.7    Hou, Y.-C.8    Chen, K.-T.9    Chen, C.-F.10    Shen, Y.-C.11
  • 18
    • 69549129495 scopus 로고    scopus 로고
    • Evodiamine represses hypoxia-induced inflammatory proteins expression and hypoxia-inducible factor 1alpha accumulation in RAW264.7
    • Liu, Y.N.; Pan, S.L.; Liao, C.H.; Huang, D.Y.; Guh, J.H.; Peng, C.Y.; Chang, Y.L.; Teng, C.M. Evodiamine represses hypoxia-induced inflammatory proteins expression and hypoxia-inducible factor 1alpha accumulation in RAW264.7. Shock 2009, 32, 263-269.
    • (2009) Shock , vol.32 , pp. 263-269
    • Liu, Y.N.1    Pan, S.L.2    Liao, C.H.3    Huang, D.Y.4    Guh, J.H.5    Peng, C.Y.6    Chang, Y.L.7    Teng, C.M.8
  • 20
    • 0034870541 scopus 로고    scopus 로고
    • Inhibitory effects of evodiamine on in vitro invasion and experimental lung metastasis of murine colon cancer cells
    • DOI 10.1248/bpb.24.917
    • Ogasawara, M.; Matsubara, T.; Suzuki, H. Inhibitory effects of evodiamine on in vitro invasion and experimental lung metastasis of murine colon cancer cells. Biol. Pharm. Bull. 2001, 24, 917-920. (Pubitemid 32750318)
    • (2001) Biological and Pharmaceutical Bulletin , vol.24 , Issue.8 , pp. 917-920
    • Ogasawara, M.1    Matsubara, T.2    Suzuki, H.3
  • 22
    • 21144442212 scopus 로고    scopus 로고
    • Evodiamine induced human melanoma A375-S2 cell death partially through interleukin 1 mediated pathway
    • DOI 10.1248/bpb.28.984
    • Wang, C.; Wang, M.W.; Tashiro, S.; Onodera, S.; Ikejima, T. Evodiamine induced human melanoma A375-S2 cell death partially through interleukin 1 mediated pathway. Biol. Pharm. Bull. 2005, 28, 984-989. (Pubitemid 40880301)
    • (2005) Biological and Pharmaceutical Bulletin , vol.28 , Issue.6 , pp. 984-989
    • Wang, C.1    Wang, M.-W.2    Tashiro, S.-I.3    Onodera, S.4    Ikejima, T.5
  • 23
    • 33749550856 scopus 로고    scopus 로고
    • Caspase-dependent and caspase-independent apoptosis induced by evodiamine in human leukemic U937 cells
    • DOI 10.1158/1535-7163.MCT-06-0167
    • Lee, T.J.; Kim, E.J.; Kim, S.; Jung, E.M.; Park, J.W.; Jeong, S.H.; Park, S.E.; Yoo, Y.H.; Kwon, T.K. Caspase-dependent and caspase-independent apoptosis induced by evodiamine in human leukemic U937 cells. Mol. Cancer Ther. 2006, 5, 2398-2407. (Pubitemid 44530477)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.9 , pp. 2398-2407
    • Lee, T.-J.1    Kim, E.J.2    Kim, S.3    Jung, E.M.4    Park, J.-W.5    Jeong, S.H.6    Park, S.E.7    Yoo, Y.H.8    Kwon, T.K.9
  • 24
    • 10344263866 scopus 로고    scopus 로고
    • Induction of mitotic arrest and apoptosis by evodiamine in human leukemic T-lymphocytes
    • Huang, Y.C.; Guh, J.H.; Teng, C.M. Induction of mitotic arrest and apoptosis by evodiamine in human leukemic T-lymphocytes. Life Sci. 2004, 75, 35-49.
    • (2004) Life Sci. , vol.75 , pp. 35-49
    • Huang, Y.C.1    Guh, J.H.2    Teng, C.M.3
  • 25
    • 34247498234 scopus 로고    scopus 로고
    • Anti-proliferative effects of evodiamine on human prostate cancer cell lines DU145 and PC3
    • DOI 10.1002/jcb.21036
    • Kan, S.F.; Yu, C.H.; Pu, H.F.; Hsu, J.M.; Chen, M.J.; Wang, P.S. Anti-proliferative effects of evodiamine on human prostate cancer cell lines DU145 and PC3. J. Cell. Biochem. 2007, 101, 44-56. (Pubitemid 46652571)
    • (2007) Journal of Cellular Biochemistry , vol.101 , Issue.1 , pp. 44-56
    • Kan, S.-F.1    Yu, C.-H.2    Pu, H.-F.3    Hsu, J.-M.4    Chen, M.-J.5    Wang, P.S.6
  • 26
    • 10344234253 scopus 로고    scopus 로고
    • Induction of mitotic arrest and apoptosis in human prostate cancer PC-3 cells by evodiamine
    • Huang, D.M.; Guh, J.H.; Huang, Y.T.; Chueh, S.C.; Chiang, P.C.; Teng, C.M. Induction of mitotic arrest and apoptosis in human prostate cancer PC-3 cells by evodiamine. J. Urol. 2005, 173, 256-261.
    • (2005) J. Urol. , vol.173 , pp. 256-261
    • Huang, D.M.1    Guh, J.H.2    Huang, Y.T.3    Chueh, S.C.4    Chiang, P.C.5    Teng, C.M.6
  • 27
    • 2942554803 scopus 로고    scopus 로고
    • Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP
    • DOI 10.1002/ijc.20138
    • Kang, S.F.; Huang, W.J.; Lin, L.C.; Wang, P.S. Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP. Int. J. Cancer 2004, 110, 641-651. (Pubitemid 38746021)
    • (2004) International Journal of Cancer , vol.110 , Issue.5 , pp. 641-651
    • Kan, S.-F.1    Huang, W.J.2    Lin, L.-C.3    Wang, P.S.4
  • 28
    • 19844377252 scopus 로고    scopus 로고
    • Antitumor mechanism of evodiamine, a constituent from Chinese herb Evodiae fructus, in human multiple-drug resistant breast cancer NCI/ADR-RES cells in vitro and in vivo
    • Liao, C.H.; Pan, S.L.; Guh, J.H.; Chang, Y.L.; Pai, H.C.; Lin, C.H.; Teng, C.M. Antitumor mechanism of evodiamine, a constituent from Chinese herb Evodiae fructus, in human multiple-drug resistant breast cancer NCI/ADR-RES cells in vitro and in vivo. Carcinogenesis 2005, 26, 968-975.
    • (2005) Carcinogenesis , vol.26 , pp. 968-975
    • Liao, C.H.1    Pan, S.L.2    Guh, J.H.3    Chang, Y.L.4    Pai, H.C.5    Lin, C.H.6    Teng, C.M.7
  • 29
    • 67249138744 scopus 로고    scopus 로고
    • Evodiamine: A novel anti-cancer alkaloid from Evodia rutaecarpa
    • Jiang, J.; Hu, C. Evodiamine: A novel anti-cancer alkaloid from Evodia rutaecarpa. Molecules 2009, 14, 1852-1859.
    • (2009) Molecules , vol.14 , pp. 1852-1859
    • Jiang, J.1    Hu, C.2
  • 31
    • 0347024204 scopus 로고    scopus 로고
    • Evodiamine induces tumor cell death through different pathways: Apoptosis and necrosis
    • Zhang. Y.; Wu, L.J.; Tashiro, S.; Onodera, S.; Ikejima, T. Evodiamine induces tumor cell death through two different pathways: Apoptosis and necrosis. Acta Pharmacol. Sin. 2004, 25, 83-89. (Pubitemid 38076083)
    • (2004) Acta Pharmacologica Sinica , vol.25 , Issue.1 , pp. 83-89
    • Zhang, Y.1    Wu, L.-J.2    Tashiro, S.-I.3    Onodera, S.4    Ikejima, T.5
  • 33
    • 20444504721 scopus 로고    scopus 로고
    • Evodiamine abolishes constitutive and inducible NF-κB activation by inhibiting IκBα kinase activation, thereby suppressing NF-κB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion
    • DOI 10.1074/jbc.M500077200
    • Takada, Y.; Kobayashi, Y.; Aggarwal, B.B. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion. J. Biol. Chem. 2005, 280, 17203-17212. (Pubitemid 41389187)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.17 , pp. 17203-17212
    • Takada, Y.1    Kobayashi, Y.2    Aggarwal, B.B.3
  • 35
    • 77955226921 scopus 로고    scopus 로고
    • Evodiamine induces caspase-dependent apoptosis and S phase arrest in human colon lovo cells
    • Zhang, C.; Fan, X.; Xu, X.; Yang, X.; Wang, X.; Liang, H.P. Evodiamine induces caspase-dependent apoptosis and S phase arrest in human colon lovo cells. Anticancer Drugs 2010, 21, 766-776.
    • (2010) Anticancer Drugs , vol.21 , pp. 766-776
    • Zhang, C.1    Fan, X.2    Xu, X.3    Yang, X.4    Wang, X.5    Liang, H.P.6
  • 36
    • 34748824207 scopus 로고    scopus 로고
    • Critical roles of reactive oxygen species in mitochondrial permeability transition in mediating evodiamine-induced human melanoma A375-S2 cell apoptosis
    • DOI 10.1080/10715760701499356, PII 782140378
    • Yang, J.; Wu, L.J.; Tashino, S.; Onodera, S.; Ikejima, T. Critical roles of reactive oxygen species in mitochondrial permeability transition in mediating evodiamine-induced human melanoma A375-S2 cell apoptosis. Free Radic. Res. 2007, 41, 1099-1108. (Pubitemid 47470847)
    • (2007) Free Radical Research , vol.41 , Issue.10 , pp. 1099-1108
    • Yang, J.1    Wu, L.-J.2    Tashino, S.-I.3    Onodera, S.4    Ikejima, T.5
  • 37
    • 40649127279 scopus 로고    scopus 로고
    • Nitric oxide activated by p38 and NF-kB facilitates apoptosis and cell cycle arrest under oxidative stress in evodiamine-treated human melanoma A375-S2 cells
    • DOI 10.1080/10715760701762407, PII 786934880
    • Yang, J.; Wu, L.J.; Tashiro, S.; Onodera, S.; Ikejima, T. Nitric oxide activated by p38 and NF-kappaB facilitates apoptosis and cell cycle arrest under oxidative stress in evodiamine-treated human melanoma A375-S2 cells. Free Radic. Res. 2008, 42, 1-11. (Pubitemid 351372186)
    • (2008) Free Radical Research , vol.42 , Issue.1 , pp. 1-11
    • Yang, J.1    Wu, L.-J.2    Tashiro, S.-I.3    Onodera, S.4    Ikejima, T.5
  • 38
    • 46649120102 scopus 로고    scopus 로고
    • Reactive oxygen species and nitric oxide regulate mitochondriadependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells
    • DOI 10.1080/10715760802112791, PII 793148321
    • Yang, J.; Wu, L.J.; Tashino, S.; Onodera, S.; Ikejima, T. Reactive oxygen species and nitric oxide regulate mitochondria-dependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells. Free Radic. Res. 2008, 42, 492-504. (Pubitemid 351935163)
    • (2008) Free Radical Research , vol.42 , Issue.5 , pp. 492-504
    • Yang, J.1    Wu, L.-J.2    Tashino, S.-I.3    Onodera, S.4    Ikejima, T.5
  • 39
    • 77953354020 scopus 로고    scopus 로고
    • Protein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma Hela cells
    • Yang, J.; Wu, L.J.; Tashino, S.; Onodera, S.; Ikejima, T. Protein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma Hela cells. Free Radic. Res. 2010, 44, 792-802.
    • (2010) Free Radic. Res. , vol.44 , pp. 792-802
    • Yang, J.1    Wu, L.J.2    Tashino, S.3    Onodera, S.4    Ikejima, T.5
  • 40
    • 77649178970 scopus 로고    scopus 로고
    • Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-kappaB signaling pathways and augmented by ubiquitin-proteasome inhibition
    • Wang, C.; Li, S.; Wang, M.W. Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-kappaB signaling pathways and augmented by ubiquitin-proteasome inhibition. Toxicol. In Vitro 2010, 24, 898-904.
    • (2010) Toxicol. in Vitro , vol.24 , pp. 898-904
    • Wang, C.1    Li, S.2    Wang, M.W.3
  • 41
    • 81255143133 scopus 로고    scopus 로고
    • Enhanced antitumor efficacy of gemcitabine by evodiamine on pancreatic cancer via regulating PI3K/Akt pathway
    • Wei, W.T.; Chen, H.; Wang, Z.H.; Ni, Z.L.; Liu, H.B.; Tong, H.F.; Guo, H.C.; Liu, D.L.; Lin, S.Z. Enhanced antitumor efficacy of gemcitabine by evodiamine on pancreatic cancer via regulating PI3K/Akt pathway. Int. J. Biol. Sci. 2012, 8, 1-14.
    • (2012) Int. J. Biol. Sci. , vol.8 , pp. 1-14
    • Wei, W.T.1    Chen, H.2    Wang, Z.H.3    Ni, Z.L.4    Liu, H.B.5    Tong, H.F.6    Guo, H.C.7    Liu, D.L.8    Lin, S.Z.9
  • 42
    • 84860394995 scopus 로고    scopus 로고
    • Evodiamine inhibits 12-O-tetradecanoylphorbol-13-acetate-induced activator protein 1 transactivation and cell transformation in human hepatocytes
    • Chao, D.C.; Lin, L.J.; Hsiang, C.Y.; Li, C.C.; Lo, H.Y.; Liang, J.A.; Kao, S.T.; Wu, S.L.; Ho, T.Y. Evodiamine inhibits 12-O-tetradecanoylphorbol-13- acetate-induced activator protein 1 transactivation and cell transformation in human hepatocytes. Phytother. Res. 2011, 25, 1018-1023.
    • (2011) Phytother. Res. , vol.25 , pp. 1018-1023
    • Chao, D.C.1    Lin, L.J.2    Hsiang, C.Y.3    Li, C.C.4    Lo, H.Y.5    Liang, J.A.6    Kao, S.T.7    Wu, S.L.8    Ho, T.Y.9
  • 43
    • 33645223907 scopus 로고    scopus 로고
    • Evodiamine inhibits in vitro angiogenesis: Implication for antitumorgenicity
    • Shyu, K.G.; Lin, S.; Lee, C.C.; Chen, E.; Lin, L.C.; Wang, B.W.; Tsai, S.C. Evodiamine inhibits in vitro angiogenesis: Implication for antitumorgenicity. Life Sci. 2006, 78, 2234-2243.
    • (2006) Life Sci. , vol.78 , pp. 2234-2243
    • Shyu, K.G.1    Lin, S.2    Lee, C.C.3    Chen, E.4    Lin, L.C.5    Wang, B.W.6    Tsai, S.C.7
  • 44
    • 16544389637 scopus 로고    scopus 로고
    • Inhibition by evodiamine of hepatocyte growth factor-induced invasion and migration of tumor cells
    • DOI 10.1248/bpb.27.578
    • Ogasawara, M.; Suzuki, H. Inhibition by evodiamine of hepatocyte growth factor-induced invasion and migration of tumor cells. Biol. Pharm. Bull. 2004, 27, 578-582. (Pubitemid 41701850)
    • (2004) Biological and Pharmaceutical Bulletin , vol.27 , Issue.4 , pp. 578-582
    • Ogasawara, M.1    Suzuki, H.2
  • 45
    • 84862790283 scopus 로고    scopus 로고
    • Evodiamine a dual catalytic inhibitor of type i and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells
    • Pan, X.; Hartley, J.M.; Hartley, J.A.; White, K.N.; Wang, Z.; Bligh, S.W. Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells. Phytomedicine 2012, 19, 618-624.
    • (2012) Phytomedicine , vol.19 , pp. 618-624
    • Pan, X.1    Hartley, J.M.2    Hartley, J.A.3    White, K.N.4    Wang, Z.5    Bligh, S.W.6
  • 46
    • 66349130754 scopus 로고    scopus 로고
    • Evodiamine stabilizes topoisomerase I-DNA cleavable complex to inhibit topoisomerase i activity
    • Chan, A.L.; Chang, W.S.; Chen, L.M.; Lee, C.M.; Chen, C.E.; Lin, C.M.; Hwang, J.L. Evodiamine stabilizes topoisomerase I-DNA cleavable complex to inhibit topoisomerase I activity. Molecules 2009, 14, 1342-1352.
    • (2009) Molecules , vol.14 , pp. 1342-1352
    • Chan, A.L.1    Chang, W.S.2    Chen, L.M.3    Lee, C.M.4    Chen, C.E.5    Lin, C.M.6    Hwang, J.L.7
  • 47
    • 80052937351 scopus 로고    scopus 로고
    • New strategies in the discovery of novel non-camptothecin topoisomerase i inhibitors
    • Sheng, C.; Miao, Z.; Zhang, W. New strategies in the discovery of novel non-camptothecin topoisomerase I inhibitors. Curr. Med. Chem. 2011, 18, 4389-4409.
    • (2011) Curr. Med. Chem. , vol.18 , pp. 4389-4409
    • Sheng, C.1    Miao, Z.2    Zhang, W.3
  • 48
    • 78149253942 scopus 로고    scopus 로고
    • Selection of evodiamine as a novel topoisomerase i inhibitor by structure-based virtual screening and hit optimization of evodiamine derivatives as antitumor agents
    • Dong, G.; Sheng, C.; Wang, S.; Miao, Z.; Yao, J.; Zhang, W. Selection of evodiamine as a novel topoisomerase I inhibitor by structure-based virtual screening and hit optimization of evodiamine derivatives as antitumor agents. J. Med. Chem. 2010, 53, 7521-7531.
    • (2010) J. Med. Chem. , vol.53 , pp. 7521-7531
    • Dong, G.1    Sheng, C.2    Wang, S.3    Miao, Z.4    Yao, J.5    Zhang, W.6
  • 49
    • 77950521443 scopus 로고    scopus 로고
    • Inhibitory effect and transcriptional impact of berberine and evodiamine on human white preadipocyte differentiation
    • Hu, Y.; Fahmy, H.; Zjawiony, J.K.; Davies, G.E. Inhibitory effect and transcriptional impact of berberine and evodiamine on human white preadipocyte differentiation. Fitoterapia 2010, 81, 259-268.
    • (2010) Fitoterapia , vol.81 , pp. 259-268
    • Hu, Y.1    Fahmy, H.2    Zjawiony, J.K.3    Davies, G.E.4
  • 50
    • 57349188918 scopus 로고    scopus 로고
    • Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats
    • Shi, J.; Yan, J.; Lei, Q.; Zhao, J.; Chen, K.; Yang, D.; Zhao, X.; Zhang, Y. Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats. Brain Res. 2009, 1247, 71-78.
    • (2009) Brain Res. , vol.1247 , pp. 71-78
    • Shi, J.1    Yan, J.2    Lei, Q.3    Zhao, J.4    Chen, K.5    Yang, D.6    Zhao, X.7    Zhang, Y.8
  • 51
    • 71749101583 scopus 로고    scopus 로고
    • Evodiamine inhibits adipogenesis via the EGFR-PKCalpha-ERK signaling pathway
    • Wang, T.; Wang, Y.; Yamashita, H. Evodiamine inhibits adipogenesis via the EGFR-PKCalpha-ERK signaling pathway. FEBS Lett. 2009, 583, 3655-3659.
    • (2009) FEBS Lett. , vol.583 , pp. 3655-3659
    • Wang, T.1    Wang, Y.2    Yamashita, H.3
  • 52
    • 37549014582 scopus 로고    scopus 로고
    • Evodiamine improves diet-induced obesity in a uncoupling protein-1-independent manner: Involvement of antiadipogenic mechanism and extracellularly regulated kinase/mitogen-activated protein kinase signaling
    • Wang, T.; Wang, Y.; Kontani, Y.; Kobayashi, Y.; Sato, Y.; Mori, N.; Yamashita, H. Evodiamine improves diet-induced obesity in a uncoupling protein-1-independent manner: Involvement of antiadipogenic mechanism and extracellularly regulated kinase/mitogen-activated protein kinase signaling. Endocrinology 2008, 149, 358-366.
    • (2008) Endocrinology , vol.149 , pp. 358-366
    • Wang, T.1    Wang, Y.2    Kontani, Y.3    Kobayashi, Y.4    Sato, Y.5    Mori, N.6    Yamashita, H.7
  • 54
    • 43149087063 scopus 로고    scopus 로고
    • Mechanisms of disease: The role of gastrointestinal hormones in appetite and obesity
    • DOI 10.1038/ncpgasthep1118, PII NCPGASTHEP1118
    • Vincent, R.P.; Ashrafian, H.; le Roux, C.W. Mechanisms of disease: The role of gastrointestinal hormones in appetite and obesity. Nat. Clin. Pract. Gastroenterol. Hepatol. 2008, 5, 268-277. (Pubitemid 351637912)
    • (2008) Nature Clinical Practice Gastroenterology and Hepatology , vol.5 , Issue.5 , pp. 268-277
    • Vincent, R.P.1    Ashrafian, H.2    Le Roux, C.W.3
  • 55
    • 0024212744 scopus 로고
    • Hypotensive effects of dehydroevodiamine, a quinazolinocarboline alkaloid isolated from Evodia rutaecarpa
    • Yang, H.Y.; Li, S.Y.; Chen, C.F. Hypotensive effects of dehydroevodiamine, a quinazolinocarboline alkaloid isolated from Evodia rutaecarpa. Asia Pac. J. Pharmacol. 1988, 3, 191-195.
    • (1988) Asia Pac. J. Pharmacol. , vol.3 , pp. 191-195
    • Yang, H.Y.1    Li, S.Y.2    Chen, C.F.3
  • 56
    • 0025113193 scopus 로고
    • The hypotensive and negative chronotropic effects of dehydroevodiamine
    • DOI 10.1016/0014-2999(90)90052-8
    • Yang, M.C.; Wu, S.L.; Kao, J.S.; Chen, C.F. The hypotensive and negative chronotropic effect of dehydroevodiamine. Eur. J. Pharmacol. 1990, 182, 537-542. (Pubitemid 20260773)
    • (1990) European Journal of Pharmacology , vol.182 , Issue.3 , pp. 537-542
    • Yang, M.C.M.1    Wu, S.-L.2    Kuo, J.-S.3    Chen, C.-F.4
  • 57
    • 0026578010 scopus 로고
    • The vasorelaxant effect of evodiamine in rat isolated mesenteric arteries: Mode of action
    • Chiou, W.F.; Chou, C.J.; Shum, A.Y.C.; Chen, C.F. The vasorelaxant effect of evodiamine in rat isolated mesenteric arteries: Mode of action. Eur. J. Pharmacol. 1992, 215, 277-283.
    • (1992) Eur. J. Pharmacol. , vol.215 , pp. 277-283
    • Chiou, W.F.1    Chou, C.J.2    Shum, A.Y.C.3    Chen, C.F.4
  • 58
    • 0030002917 scopus 로고    scopus 로고
    • Comparative study on vasodilatory effects of three quinazoline alkaloids isolated from Evodia rutaecarpa
    • Chiou, W.F.; Liao, J.F.; Chen, C.F. Comparative study on vasodilatory effects of three quinazoline alkaloids isolated from Evodia rutaecarpa. J. Nat. Prod. 1996, 59, 374-378.
    • (1996) J. Nat. Prod. , vol.59 , pp. 374-378
    • Chiou, W.F.1    Liao, J.F.2    Chen, C.F.3
  • 59
    • 0019814238 scopus 로고
    • In vivo and in vitro studies on the mechanism of cardiovascular effects of Wu-Chu-Yu (Evodiae fructus)
    • Chen, C.F.; Chen, S.M.; Lin, M.T.; Chow, S.Y. In vivo and in vitro studies on the mechanism of cardiovascular effects of Wu-Chu-Yu (Evodiae fructus). Am. J. Chin. Med. 1981, 9, 39-47. (Pubitemid 12190231)
    • (1981) American Journal of Chinese Medicine , vol.9 , Issue.1 , pp. 39-47
    • Chen, C.F.1    Chen, S.M.2    Lin, M.T.3    Chow, S.Y.4
  • 60
    • 0034961783 scopus 로고    scopus 로고
    • Inhibitory effect of evodiamine on aldosterone release by zona glomerulosa cells in male rats
    • Hung, P.H.; Lin, L.C.; Wang, G.J.; Chen, C.F.; Wang, P.S. Inhibitory effect of evodiamine on aldosterone release by Zona glomerulosa cells in male rats. Chin. J. Physiol. 2001, 44, 53-57. (Pubitemid 32601324)
    • (2001) Chinese Journal of Physiology , vol.44 , Issue.2 , pp. 53-57
    • Hung, P.-H.1    Lin, L.-C.2    Wang, G.-J.3    Chen, C.-F.4    Wang, P.S.5
  • 61
    • 0035046155 scopus 로고    scopus 로고
    • The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: Possible involvement of vanilloid receptors
    • DOI 10.1055/s-2001-12008
    • Kobayashi, Y.; Hoshikuma, K.; Nakano, Y.; Yokoo, Y.; Kamiya, T. The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: Possible involvement of vanilloid receptors. Planta Med. 2001, 67, 244-248. (Pubitemid 32304195)
    • (2001) Planta Medica , vol.67 , Issue.3 , pp. 244-248
    • Kobayashi, Y.1    Hoshikuma, K.2    Nakano, Y.3    Yokoo, Y.4    Kamiya, T.5
  • 62
    • 0037355505 scopus 로고    scopus 로고
    • Protective effects of calcitonin gene-related peptide-mediated evodiamine on guinea-pig cardiac anaphylaxis
    • DOI 10.1007/s00210-002-0677-0
    • Rang, W.Q.; Du, Y.H.; Hu, C.P.; Ye, F.; Tan, G.S.; Deng, H.W.; Li, Y.J. Protective effects of calcitonin gene-related peptide-mediated evodiamine on guinea-pig cardiac anaphylaxis. Naunyn Schmiedebergs Arch. Pharmacol. 2003, 367, 306-311. (Pubitemid 36408013)
    • (2003) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.367 , Issue.3 , pp. 306-311
    • Rang, W.-Q.1    Du, Y.-H.2    Hu, C.-P.3    Ye, F.4    Tan, G.-S.5    Deng, H.-W.6    Li, Y.-J.7
  • 63
    • 11944260890 scopus 로고    scopus 로고
    • Protective effects of rutaecarpine in cardiac anaphylactic injury is mediated by CGRP
    • Yi, H.H.; Rang, W.Q.; Deng, P.Y.; Hu, C.P.; Liu, G.Z.; Tan, G.S.; Xu, K.P.; Li, Y.J. Protective effects of rutaecarpine in cardiac anaphylactic injury is mediated by CGRP. Planta Med. 2004, 70, 1135-1139.
    • (2004) Planta Med. , vol.70 , pp. 1135-1139
    • Yi, H.H.1    Rang, W.Q.2    Deng, P.Y.3    Hu, C.P.4    Liu, G.Z.5    Tan, G.S.6    Xu, K.P.7    Li, Y.J.8
  • 64
    • 9944239238 scopus 로고    scopus 로고
    • Involvement of CGRP in the inhibitory effect of rutaecarpine on vasoconstriction induced by anaphylaxis in guinea pig
    • DOI 10.1016/j.regpep.2004.08.001, PII S016701150400268X
    • Yu, J.; Tan, G.S.; Deng, P.Y.; Xu, K.P.; Hu, C.P.; Li, Y.J. Involvement of CGRP in the inhibitory effect of rutaecarpine on vasoconstriction induced by anaphylaxis in guinea pig. Regul. Pept. 2005, 125, 93-97. (Pubitemid 39593713)
    • (2005) Regulatory Peptides , vol.125 , Issue.1-3 , pp. 93-97
    • Yu, J.1    Tan, G.-S.2    Deng, P.-Y.3    Xu, K.-P.4    Hu, C.-P.5    Li, Y.-J.6
  • 65
    • 11944258043 scopus 로고    scopus 로고
    • Protective effects of evodiamine on myocardial ischemia-reperfusion injury in rats
    • DOI 10.1055/s-2004-835841
    • Rang, W.Q.; Du, Y.H.; Hu, C.P.; Ye, F.; Xu, K.P.; Peng, J.; Deng, H.W.; Li, Y.J. Protective effects of evodiamine on myocardial ischemia-reperfusion injury in rats. Planta Med. 2004, 70, 1140-1143. (Pubitemid 40101093)
    • (2004) Planta Medica , vol.70 , Issue.12 , pp. 1140-1143
    • Rang, W.-Q.1    Du, Y.-H.2    Hu, C.-P.3    Ye, F.4    Xu, K.-P.5    Peng, J.6    Deng, H.-W.7    Li, Y.-J.8
  • 66
    • 0036676755 scopus 로고    scopus 로고
    • The cardioprotection of rutaecarpine is mediated by endogenous calcitonin related-gene peptide through activation of vanilloid receptors in guinea-pig hearts
    • DOI 10.1055/s-2002-33794
    • Hu, C.P.; Xiao, L.; Deng, H.W.; Li, Y.J. The cardioprotection of rutaecarpine is mediated by endogenous calcitonin release-gene peptide through activation of vanilloid receptors in guinea-pig hearts. Planta Med. 2002, 68, 705-709. (Pubitemid 35013381)
    • (2002) Planta Medica , vol.68 , Issue.8 , pp. 705-709
    • Hu, C.-P.1    Xiao, L.2    Deng, H.-W.3    Li, Y.-J.4
  • 67
    • 66149189450 scopus 로고    scopus 로고
    • Evodiamine and rutaecarpine inhibit migration by LIGHT via suppression of NADPH oxidase activation
    • Heo, S.K.; Yun, H.J.; Yi, H.S.; Noh, E.K.; Park, S.D. Evodiamine and rutaecarpine inhibit migration by LIGHT via suppression of NADPH oxidase activation. J. Cell. Biochem. 2009, 107, 123-133.
    • (2009) J. Cell. Biochem. , vol.107 , pp. 123-133
    • Heo, S.K.1    Yun, H.J.2    Yi, H.S.3    Noh, E.K.4    Park, S.D.5
  • 68
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • DOI 10.1038/nature02621
    • Mattson, M.P. Pathways towards and away from Alzheimer's disease. Nature 2004, 430, 631-639. (Pubitemid 39061671)
    • (2004) Nature , vol.430 , Issue.7000 , pp. 631-639
    • Mattson, M.P.1
  • 69
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • DOI 10.1126/science.1072994
    • Hardy, J.; Selkoe, D.J. The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 2002, 297, 353-356. (Pubitemid 34790756)
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 70
    • 7044235122 scopus 로고    scopus 로고
    • Effects of green tea polyphenol on cognitive and acetylcholinesterase activities
    • DOI 10.1271/bbb.68.1977
    • Kim, H.K.; Kim, M.; Kim, S.; Kim, M.; Chung, J.H. Effects of green tea polyphenol on cognitive and acetylcholinesterase activities. Biosci. Biotechnol. Biochem. 2004, 68, 1977-1979. (Pubitemid 39415267)
    • (2004) Bioscience, Biotechnology and Biochemistry , vol.68 , Issue.9 , pp. 1977-1979
    • Kim, H.K.1    Kim, M.2    Kim, S.3    Kim, M.4    Chung, J.H.5
  • 71
    • 39049177580 scopus 로고    scopus 로고
    • Effects of green tea polyphenol on the behaviour of Alzheimer's disease like mice induced by D-galactose and Abeta25-35
    • Lu, J.H.; Guo, J.; Yang, W.H. Effects of green tea polyphenol on the behaviour of Alzheimer's disease like mice induced by D-galactose and Abeta25-35. Zhong Yao Cai 2006, 29, 352-354.
    • (2006) Zhong Yao Cai , vol.29 , pp. 352-354
    • Lu, J.H.1    Guo, J.2    Yang, W.H.3
  • 72
    • 27844497059 scopus 로고    scopus 로고
    • Resveratrol promotes clearance of Alzheimer's disease amyloid-β peptides
    • DOI 10.1074/jbc.M508246200
    • Marambaud, P.; Zhao, H.; Davies, P. Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J. Biol. Chem. 2005, 280, 37377-37382. (Pubitemid 41642343)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.45 , pp. 37377-37382
    • Marambaud, P.1    Zhao, H.2    Davies, P.3
  • 73
    • 60249098801 scopus 로고    scopus 로고
    • Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease
    • Karuppagounder, S.S.; Pinto, J.T.; Xu, H.; Chen, H.L.; Beal, M.F.; Gibson, G.E. Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem. Int. 2009, 54, 111-118.
    • (2009) Neurochem. Int. , vol.54 , pp. 111-118
    • Karuppagounder, S.S.1    Pinto, J.T.2    Xu, H.3    Chen, H.L.4    Beal, M.F.5    Gibson, G.E.6
  • 75
    • 0028298985 scopus 로고
    • Increased feline cerebral blood flow induced by dehydroevodiamine hydrochloride from Evodia rutaecarpa
    • Haji, A.; Momose, Y.; Takeda, R.; Nakanishi, S.; Hiriachi, T.; Arisawa, M. Increased feline cerebral blood flow induced by dehydroevodiamine hydrochloride from Evodia rutaecarpa. J. Nat. Prod. 1994, 57, 387-389. (Pubitemid 24123504)
    • (1994) Journal of Natural Products , vol.57 , Issue.3 , pp. 387-389
    • Haji, A.1    Momose, Y.2    Takeda, R.3    Nakanishi, S.4    Horiuchi, T.5    Arisawa, M.6
  • 76
    • 79952367764 scopus 로고    scopus 로고
    • Evodiamine improves congnitive abilities in SAMP8 and APP(swe)/PS1(ΔE9) transgenic mouse models of Alzheimer's disease
    • Yuan, S.M.; Gao, K.; Wang, D.M.; Quan, X.Z.; Liu, J.N.; Ma, C.M.; Qin, C.; Zhang, L.F. Evodiamine improves congnitive abilities in SAMP8 and APP(swe)/PS1(ΔE9) transgenic mouse models of Alzheimer's disease. Acta Pharmacol. Sin. 2011, 32, 295-302.
    • (2011) Acta Pharmacol. Sin. , vol.32 , pp. 295-302
    • Yuan, S.M.1    Gao, K.2    Wang, D.M.3    Quan, X.Z.4    Liu, J.N.5    Ma, C.M.6    Qin, C.7    Zhang, L.F.8
  • 77
    • 0029827996 scopus 로고    scopus 로고
    • Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa
    • DOI 10.1055/s-2006-957926
    • Park, C.H.; Kim, S.H.; Choi, W.; Lee, Y.J.; Kim, J.S.; Kang, S.S.; Suh, Y.H. Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa. Planta Med. 1996, 62, 405-409. (Pubitemid 26370329)
    • (1996) Planta Medica , vol.62 , Issue.5 , pp. 405-409
    • Park, C.H.1    Kim, S.-H.2    Choi, W.3    Lee, Y.-J.4    Kim, J.S.5    Kang, S.S.6    Suh, Y.H.7
  • 78
    • 0029044370 scopus 로고
    • Atanine (3-dimethylallyl-4-methoxy-2-quinolone) an alkaloid with anthelmintic activity from the chinese medicinal plant evodia rutaecarpa
    • Perrett, S.; Whitfield, P.J. Atanine (3-dimethylallyl-4-methoxy-2- quinolone), an alkaloid with anthelmintic activity from the Chinese medicinal plant, Evodia rutaecarpa. Planta Med. 1995, 61, 276-278.
    • (1995) Planta Med. , vol.61 , pp. 276-278
    • Perrett, S.1    Whitfield, P.J.2
  • 80
    • 0033958657 scopus 로고    scopus 로고
    • Highly selective antibacterial activity of novel alkyl quinolone alkaloids from a Chinese herbal medicine, Gosyuyu (Wu-Chu-Yu), against Helicobacter pylori in vitro
    • Hamasaki, N.; Ishii, E.; Tominaga, K.; Tezuka, Y.; Nagaoka, T.; Kadota, S.; Kuroki, T.; Yano, I. Highly selective antibacterial activity of novel alkyl quinolone alkaloids from a Chinese herbal medicine, Gosyuyu (Wu-Chu-Yu), against Helicobacter pylori in vitro. Microbiol. Immunol. 2000, 44, 9-15. (Pubitemid 30073693)
    • (2000) Microbiology and Immunology , vol.44 , Issue.1 , pp. 9-15
    • Hamasaki, N.1    Ishii, E.2    Tominaga, K.3    Tezuka, Y.4    Nagaoka, T.5    Kadota, S.6    Kuroki, T.7    Yano, I.8
  • 83
    • 80052685345 scopus 로고    scopus 로고
    • Evodia rutaecarpa and three major alkaloids abrogate influenza A virus (H1N1)-induced chemokines production and cell migration
    • Chiou, W.F.; Ko, H.C.; Wei, B.L. Evodia rutaecarpa and three major alkaloids abrogate influenza A virus (H1N1)-induced chemokines production and cell migration. Evid. Based Complement. Alternat. Med. 2011, 2011, 750513.
    • (2011) Evid. Based Complement. Alternat. Med. , vol.2011 , pp. 750513
    • Chiou, W.F.1    Ko, H.C.2    Wei, B.L.3
  • 84
    • 0034926291 scopus 로고    scopus 로고
    • The vanilloid receptor: A molecular gateway to the pain pathway
    • DOI 10.1146/annurev.neuro.24.1.487
    • Caterina, M.; Julius, D. The vanilloid receptor: A molecular gateway to the pain pathway. Annu. Rev. Neurosci. 2001, 24, 487-517. (Pubitemid 32695237)
    • (2001) Annual Review of Neuroscience , vol.24 , pp. 487-517
    • Caterina, M.J.1    Julius, D.2
  • 86
    • 73449139052 scopus 로고    scopus 로고
    • The vanilloid receptor TRPV-1: Role in cardiovascular and gastrointestinal protection
    • Peng, L.; Li, Y.J. The vanilloid receptor TRPV-1: Role in cardiovascular and gastrointestinal protection. Eur. J. Pharmacol. 2010, 627, 1-7.
    • (2010) Eur. J. Pharmacol. , vol.627 , pp. 1-7
    • Peng, L.1    Li, Y.J.2
  • 87
    • 0030892810 scopus 로고    scopus 로고
    • Antinociceptive activities of 70% methanol extract of evodiae fructus (fruit of Evodia rutaecarpa var. bodinieri) and its alkaloidal components
    • Matsuda, H.; Wu, T.X.; Tanaka, T.; Linuma, M.; Kubo, M. Antinociceptive activities of 70% methanol extract of Evodiae Fructus (fruit of Evodia rutaecarpavar. bodinieri) and its alkaloidal components. Biol. Pharm. Bull. 1997, 20, 243-248. (Pubitemid 27148972)
    • (1997) Biological and Pharmaceutical Bulletin , vol.20 , Issue.3 , pp. 243-248
    • Matsuda, H.1    Wu, J.-X.2    Tanaka, T.3    Iinuma, M.4    Kubo, M.5
  • 88
    • 0025764151 scopus 로고
    • Pharmacological properties of galenical preparation, XIV. Body temperature retaining effect of the Chinese traditional medicine, goshuyu-to and component crude drugs
    • Kano, Y.; Zong, Q.N.; Komatsu, K. Pharmacological properties of galenical preparation, XIV. Body temperature retaining effect of the Chinese traditional medicine, "goshuyu-to" and component crude drugs. Chem. Pharm. Bull. (Tokyo) 1991, 39, 690-692.
    • (1991) Chem. Pharm. Bull. (Tokyo) , vol.39 , pp. 690-692
    • Kano, Y.1    Zong, Q.N.2    Komatsu, K.3
  • 89
    • 0028842109 scopus 로고
    • Thermoregulatory effects of alkaloids isolated from Wu-Chu-Yu in afebrile and febrile rats
    • Tsai, T.H.; Lee, T.F.; Chen, C.F.; Wang, L.C. Thermoregulatory effects of alkaloids isolated from Wu-Chu-Yu in afebrile and febrile rats. Pharmacol. Biochem. Behav. 1995, 50, 293-298.
    • (1995) Pharmacol. Biochem. Behav. , vol.50 , pp. 293-298
    • Tsai, T.H.1    Lee, T.F.2    Chen, C.F.3    Wang, L.C.4
  • 90
    • 0032715166 scopus 로고    scopus 로고
    • Effects of evodiamine on the secretion of testosterone in rat testicular interstitial cells
    • Lin, H.; Tsai, S.C.; Chen, J.J.; Chiao, Y.C.; Wang, S.W.; Wang, G.J.; Chen, C.F.; Wang, P.S. Effects of evodiamine on the secretion of testosterone in rat testicular interstitial cells. Metabolism 1999, 48, 1532-1535.
    • (1999) Metabolism , vol.48 , pp. 1532-1535
    • Lin, H.1    Tsai, S.C.2    Chen, J.J.3    Chiao, Y.C.4    Wang, S.W.5    Wang, G.J.6    Chen, C.F.7    Wang, P.S.8
  • 92
    • 70349251216 scopus 로고    scopus 로고
    • Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats
    • Yu, P.L.; Chao, H.L.; Wang, S.W.; Wang, P.S. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. J. Cell. Biochem. 2009, 108, 469-475.
    • (2009) J. Cell. Biochem. , vol.108 , pp. 469-475
    • Yu, P.L.1    Chao, H.L.2    Wang, S.W.3    Wang, P.S.4
  • 93
    • 0024802401 scopus 로고
    • Antianoxic action of evodiamine, an alkaloid in Evodia rutaecarpa fruit
    • DOI 10.1016/0378-8741(89)90090-1
    • Yamahara, J.; Yamada, T.; Kitani, T.; Naitoh, Y.; Fujimura, H. Antianoxic action of evodiamine, an alkaloid in Evodia rutaecarpa fruit. J. Ethnopharmacol. 1989, 27, 185-192. (Pubitemid 20018073)
    • (1989) Journal of Ethnopharmacology , vol.27 , Issue.1-2 , pp. 185-192
    • Yamahara, J.1    Yamada, T.2    Kitani, T.3    Naitoh, Y.4    Fujimura, H.5
  • 94
    • 33846095017 scopus 로고    scopus 로고
    • In vitro and in vivo antiallergic effect of the fructus of Evodia rutaecarpa and its constituents
    • DOI 10.1248/bpb.30.197
    • Shin, Y.W.; Bae, E.A.; Cai, X.F.; Lee, J.J.; Kim, D.H. In vitro and in vivo antiallergic effects on the fruits of Evodia rutaecarpa and its constituents. Biol. Pharm. Bull. 2007, 30, 197-199. (Pubitemid 46066347)
    • (2007) Biological and Pharmaceutical Bulletin , vol.30 , Issue.1 , pp. 197-199
    • Shin, Y.-W.1    Bae, E.-A.2    Cai, X.F.3    Lee, J.J.4    Kim, D.-H.5
  • 95
    • 84866739097 scopus 로고    scopus 로고
    • Berberine and evodiamine influence serotonin transporter (5-HTT) expression via the 5-HTT-linked polymorphic region
    • Hu, Y.; Ehli, E.A.; Hudziak, J.J.; Davies, G.E. Berberine and evodiamine influence serotonin transporter (5-HTT) expression via the 5-HTT-linked polymorphic region. Pharmacogenomics J. 2012, 12, 372-378.
    • (2012) Pharmacogenomics J. , vol.12 , pp. 372-378
    • Hu, Y.1    Ehli, E.A.2    Hudziak, J.J.3    Davies, G.E.4
  • 96
    • 0033870753 scopus 로고    scopus 로고
    • The bronchoconstrictive action of evodiamine, an indoloquinazoline alkaloid isolated from the fruits of evodia rutaecarpa, on guinea-pig isolated bronchus: Possible involvement on vanilloid receptors
    • DOI 10.1055/s-2000-8615
    • Kobayashi, Y.; Nakano, Y.; Hoshikuma, K.; Yokoo, Y.; Kamiya, T. The bronchoconstrictive action of evodiamine, an indoloquinazoline alkaloid isolated from the fruits of Evodia rutaecarpa, on guinea-pig isolated bronchus: Possible involvement on vanilloid receptors. Planta Med. 2000, 66, 526-530. (Pubitemid 30627540)
    • (2000) Planta Medica , vol.66 , Issue.6 , pp. 526-530
    • Kobayashi, Y.1    Nakano, Y.2    Hoshikuma, K.3    Yokoo, Y.4    Kamiya, T.5
  • 97
    • 84857406206 scopus 로고    scopus 로고
    • Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors
    • Guerrant, W.; Patil, V.; Canzoneri, J.C.; Oyelere, A.K. Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors. J. Med. Chem. 2012, 55, 1465-1477.
    • (2012) J. Med. Chem. , vol.55 , pp. 1465-1477
    • Guerrant, W.1    Patil, V.2    Canzoneri, J.C.3    Oyelere, A.K.4
  • 98
    • 84872187434 scopus 로고    scopus 로고
    • Essential role of transient receptor potential vanilloid type 1 in evodiamine-mediated protection against atherosclerosis
    • Wei, J.; Ching, L.C.; Zhao, J.F.; Shyue, S.K.; Lee, H.F.; Kou, Y.R.; Lee, T.S. Essential role of transient receptor potential vanilloid type 1 in evodiamine-mediated protection against atherosclerosis. Acta Physiol. (Oxf.) 2013, 207, 299-307.
    • (2013) Acta Physiol. (Oxf.) , vol.207 , pp. 299-307
    • Wei, J.1    Ching, L.C.2    Zhao, J.F.3    Shyue, S.K.4    Lee, H.F.5    Kou, Y.R.6    Lee, T.S.7
  • 100
    • 84856084105 scopus 로고    scopus 로고
    • Aging reverses the role of the transient receptor potential vanilloid-1 channel in systemic inflammation from anti-inflammatory to proinflammatory
    • Wanner, S.P.; Garami, A.; Pakai, E.; Oliveira, D.L.; Gavva, N.R.; Coimbra, C.C.; Romanovsky, A.A. Aging reverses the role of the transient receptor potential vanilloid-1 channel in systemic inflammation from anti-inflammatory to proinflammatory. Cell Cycle 2012, 11, 343-349.
    • (2012) Cell Cycle , vol.11 , pp. 343-349
    • Wanner, S.P.1    Garami, A.2    Pakai, E.3    Oliveira, D.L.4    Gavva, N.R.5    Coimbra, C.C.6    Romanovsky, A.A.7
  • 102
    • 84869882221 scopus 로고    scopus 로고
    • Manipulating molecular switches in brown adipocytes and their precursors: A therapeutic potential
    • Birerdinc, A.; Jarrar, M.; Stotish, T.; Randhawa, M.; Baranova, A. Manipulating molecular switches in brown adipocytes and their precursors: A therapeutic potential. Prog. Lipid Res. 2012, 52, 51-61.
    • (2012) Prog. Lipid Res. , vol.52 , pp. 51-61
    • Birerdinc, A.1    Jarrar, M.2    Stotish, T.3    Randhawa, M.4    Baranova, A.5
  • 103
    • 84857784321 scopus 로고    scopus 로고
    • TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice
    • Luo, Z.; Ma, L.; Zhao, Z.; He, H.; Yang, D.; Feng, X.; Ma, S.; Chen, X.; Zhu, T.; Cao, T.; et al. TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice. Cell Res. 2012, 22, 551-564.
    • (2012) Cell Res. , vol.22 , pp. 551-564
    • Luo, Z.1    Ma, L.2    Zhao, Z.3    He, H.4    Yang, D.5    Feng, X.6    Ma, S.7    Chen, X.8    Zhu, T.9    Cao, T.10
  • 105
    • 84862869336 scopus 로고    scopus 로고
    • Development of PAC-14028, a novel transient receptor potential vanilloid type 1 (TRPV1) channel antagonist as a new drug for refractory skin diseases
    • Lim, K.M.; Park, Y.H. Development of PAC-14028, a novel transient receptor potential vanilloid type 1 (TRPV1) channel antagonist as a new drug for refractory skin diseases. Arch. Pharm. Res. 2012, 35, 393-396.
    • (2012) Arch. Pharm. Res. , vol.35 , pp. 393-396
    • Lim, K.M.1    Park, Y.H.2
  • 106
    • 84874637703 scopus 로고    scopus 로고
    • Antioncogenic effects of transient receptor potential vanilloid 1 in the progression of transitional urothelial cancer of human bladder
    • Santoni, G.; Caprodossi, S.; Farfariello, V.; Liberati, S.; Gismondi, A.; Amantini, C. Antioncogenic effects of transient receptor potential vanilloid 1 in the progression of transitional urothelial cancer of human bladder. ISRN Urol. 2012, 2012, 458238.
    • (2012) ISRN Urol. , vol.2012 , pp. 458238
    • Santoni, G.1    Caprodossi, S.2    Farfariello, V.3    Liberati, S.4    Gismondi, A.5    Amantini, C.6
  • 108
    • 84864395482 scopus 로고    scopus 로고
    • DNA-topoisomerases and their functions in cell
    • Giliarov, D.A.; Shkundina, I.S. DNA-topoisomerases and their functions in cell. Mol. Biol. (Mosk.) 2012, 46, 52-63.
    • (2012) Mol. Biol. (Mosk.) , vol.46 , pp. 52-63
    • Giliarov, D.A.1    Shkundina, I.S.2
  • 109
    • 84861485138 scopus 로고    scopus 로고
    • QSAR modeling on benzo[c]phenanthridine analogues as topoisomerase i inhibitors and anti-cancer agents
    • Thai, K.M.; Bui, Q.H.; Tran, T.D.; Huynh, T.N. QSAR modeling on benzo[c]phenanthridine analogues as topoisomerase I inhibitors and anti-cancer agents. Molecules 2012, 17, 5690-5712.
    • (2012) Molecules , vol.17 , pp. 5690-5712
    • Thai, K.M.1    Bui, Q.H.2    Tran, T.D.3    Huynh, T.N.4
  • 110
    • 84857239566 scopus 로고    scopus 로고
    • Dihydroxylated 2,4,6-triphenyl pyridines: Synthesis, topoisomerase i and II inhibitory activity, cytotoxicity, and structure-activity relationship study
    • Karki, R.; Thapa, P.; Yoo, H.Y.; Kadayat, T.M.; Park, P.H.; Na, Y.; Lee, E.; Jeon, K.H.; Cho, W.J.; Choi, H.; et al. Dihydroxylated 2,4,6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study. Eur. J. Med. Chem. 2012, 49, 219-228.
    • (2012) Eur. J. Med. Chem. , vol.49 , pp. 219-228
    • Karki, R.1    Thapa, P.2    Yoo, H.Y.3    Kadayat, T.M.4    Park, P.H.5    Na, Y.6    Lee, E.7    Jeon, K.H.8    Cho, W.J.9    Choi, H.10
  • 111
    • 84862809544 scopus 로고    scopus 로고
    • Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles
    • Lee, C.H.; Hsieh, M.Y.; Hsin, L.W.; Chen, H.C.; Lo, S.C.; Fan, J.R.; Chen, W.R.; Chen, H.W.; Chan, N.L.; Li, T.K. Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles. Biochem. Pharmacol. 2012, 83, 1208-1216.
    • (2012) Biochem. Pharmacol. , vol.83 , pp. 1208-1216
    • Lee, C.H.1    Hsieh, M.Y.2    Hsin, L.W.3    Chen, H.C.4    Lo, S.C.5    Fan, J.R.6    Chen, W.R.7    Chen, H.W.8    Chan, N.L.9    Li, T.K.10
  • 112
    • 84859364840 scopus 로고    scopus 로고
    • Bacterial DNA replication enzymes as targets for antibacterial drug discovery
    • Sanyal, G.; Doig, P. Bacterial DNA replication enzymes as targets for antibacterial drug discovery. Expert Opin. Drug Discov. 2012, 7, 327-339.
    • (2012) Expert Opin. Drug Discov. , vol.7 , pp. 327-339
    • Sanyal, G.1    Doig, P.2
  • 115
    • 84860717980 scopus 로고    scopus 로고
    • Topoisomerase IIβ regulates base excision repair capacity of neurons
    • Gupta, K.P.; Swain, U.; Rao, K.S.; Kondapi, A.K. Topoisomerase IIβ regulates base excision repair capacity of neurons. Mech. Ageing Dev. 2012, 133, 203-213.
    • (2012) Mech. Ageing Dev. , vol.133 , pp. 203-213
    • Gupta, K.P.1    Swain, U.2    Rao, K.S.3    Kondapi, A.K.4
  • 116
    • 0026725943 scopus 로고
    • Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor
    • Burbach, K.M.; Poland, A.; Bradfield, C.A. Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proc. Natl. Acad. Sci. USA 1992, 89, 8185-8189.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8185-8189
    • Burbach, K.M.1    Poland, A.2    Bradfield, C.A.3
  • 117
    • 0023742858 scopus 로고
    • Association of the Ah receptor with the 90-kDa heat shock protein
    • Perdew, G.H. Association of the Ah receptor with the 90-kDa heat shock protein. J. Biol. Chem. 1988, 263, 13802-13805.
    • (1988) J. Biol. Chem. , vol.263 , pp. 13802-13805
    • Perdew, G.H.1
  • 118
    • 0033531928 scopus 로고    scopus 로고
    • Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (Aryl hydrocarbon) receptor
    • Kazlauskas, A.; Poellinger, L.; Pongratz, I. Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (Aryl hydrocarbon) receptor. J. Biol. Chem. 1999, 274, 13519-13524.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13519-13524
    • Kazlauskas, A.1    Poellinger, L.2    Pongratz, I.3
  • 119
    • 0031882767 scopus 로고    scopus 로고
    • Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity
    • Meyer, B.K.; Pray-Grant, M.G.; Vanden Heuvel, J.P.; Perdew, G.H. Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity. Mol. Cell. Biol. 1998, 18, 978-988. (Pubitemid 28063432)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.2 , pp. 978-988
    • Meyer, B.K.1    Pray-Grant, M.G.2    Vanden Heuvel, J.P.3    Perdew, G.H.4
  • 120
    • 0033861976 scopus 로고    scopus 로고
    • Analysis of the complex relationship between nuclear export and aryl hydrocarbon receptor-mediated gene regulation
    • DOI 10.1128/MCB.20.16.6095-6104.2000
    • Pollenz, R.S.; Barbour, E.R. Analysis of the complex relationship between nuclear export and aryl hydrocarbon receptor-mediated gene regulation. Mol. Cell. Biol. 2000, 20, 6095-6104. (Pubitemid 30613057)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.16 , pp. 6095-6104
    • Pollenz, R.S.1    Barbour, E.R.2
  • 121
  • 122
    • 0026625037 scopus 로고
    • Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor
    • Reyes, H.; Reisz-Porszasz, S.; Hankinson, O. Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor. Science 1992, 256, 1193-1195.
    • (1992) Science , vol.256 , pp. 1193-1195
    • Reyes, H.1    Reisz-Porszasz, S.2    Hankinson, O.3
  • 123
    • 30044452058 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries
    • DOI 10.1124/mol.105.018705
    • Tijet, N.; Boutros, P.C.; Moffat, I.D.; Okey, A.B.; Tuomisto, J.; Pohjanvirta, R. Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries. Mol. Pharmacol. 2006, 69, 140-153. (Pubitemid 43048901)
    • (2006) Molecular Pharmacology , vol.69 , Issue.1 , pp. 140-153
    • Tijet, N.1    Boutros, P.C.2    Moffat, I.D.3    Okey, A.B.4    Tuomisto, J.5    Pohjanvirta, R.6
  • 124
    • 0021060932 scopus 로고
    • 1-450 in wild type and variant mouse hepatoma cells
    • Israel, D.I.; Whitlock, J.P. Induction of mRNA specific for cytochrome P1-450 in wild type and variant mouse hepatoma cells. J. Biol. Chem. 1983, 258, 10390-10394. (Pubitemid 14241199)
    • (1983) Journal of Biological Chemistry , vol.258 , Issue.17 , pp. 10390-10394
    • Israel, D.I.1    Whitlock Jr., J.P.2
  • 127
    • 84868117782 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-dependence of dioxin's effects on constitutive mouse hepatic cytochromes P450 and growth hormone signaling components
    • Lee, C.; Riddick, D.S. Aryl hydrocarbon receptor-dependence of dioxin's effects on constitutive mouse hepatic cytochromes P450 and growth hormone signaling components. Can. J. Physiol. Pharmacol. 2012, 90, 1354-1363.
    • (2012) Can. J. Physiol. Pharmacol. , vol.90 , pp. 1354-1363
    • Lee, C.1    Riddick, D.S.2
  • 129
    • 84874594968 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor in tumor immunity
    • Platten, M.; Litzenburger, U.; Wick, W. The aryl hydrocarbon receptor in tumor immunity. Oncoimmunology 2012, 1, 396-397.
    • (2012) Oncoimmunology , vol.1 , pp. 396-397
    • Platten, M.1    Litzenburger, U.2    Wick, W.3
  • 132
    • 84863284796 scopus 로고    scopus 로고
    • Preparation of evodiamine solid dispersions and its pharmacokinetics
    • Xu, H.; Zhang, T.; Yang, H.; Xiao, X.; Bian, Y.; Si, D.; Liu, C. Preparation of evodiamine solid dispersions and its pharmacokinetics. Indian J. Pharm. Sci. 2011, 73, 276-281.
    • (2011) Indian J. Pharm. Sci. , vol.73 , pp. 276-281
    • Xu, H.1    Zhang, T.2    Yang, H.3    Xiao, X.4    Bian, Y.5    Si, D.6    Liu, C.7
  • 133
    • 84862877338 scopus 로고    scopus 로고
    • Design and evaluation of a novel evodiamine-phospholipid complex for improved oral bioavailability
    • Tan, Q.; Liu, S.; Chen, X.; Wu, M.; Wang, H.; Yin, H.; He, D.; Xiong, H.; Zhang, J. Design and evaluation of a novel evodiamine-phospholipid complex for improved oral bioavailability. AAPS PharmSciTech. 2012, 13, 534-547.
    • (2012) AAPS PharmSciTech. , vol.13 , pp. 534-547
    • Tan, Q.1    Liu, S.2    Chen, X.3    Wu, M.4    Wang, H.5    Yin, H.6    He, D.7    Xiong, H.8    Zhang, J.9
  • 134
    • 0027501222 scopus 로고
    • Pharmacological properties of galenical preparation. XVI. Pharmacokinetics of evodiamine and the metabolite in rats
    • Komatsu, K.; Wakame, K.; Kano, Y. Pharmacological properties of galenical preparation. XVI. Pharmacokinetics of evodiamine and the metabolite in rats. Biol. Pharm. Bull. 1993, 16, 935-938. (Pubitemid 23329810)
    • (1993) Biological and Pharmaceutical Bulletin , vol.16 , Issue.9 , pp. 935-938
    • Komatsu, K.-I.1    Wakame, K.2    Kano, Y.3
  • 135
    • 0029015253 scopus 로고
    • High-performance liquid chromatographic determination of evodiamine in rat plasma: Application to pharmacokinetic studies
    • Jeng, K.F.; Lin, Y.H.; Lin, L.C.; Chou, C.J.; Tsai, T.H.; Chen, C.F. High-performance liquid chromatographic determination of evodiamine in rat plasma: Application to pharmacokinetic studies. J. Chromatogr. B Biomed. Appl. 1995, 668, 343-345.
    • (1995) J. Chromatogr. B Biomed. Appl. , vol.668 , pp. 343-345
    • Jeng, K.F.1    Lin, Y.H.2    Lin, L.C.3    Chou, C.J.4    Tsai, T.H.5    Chen, C.F.6
  • 136
    • 84862922006 scopus 로고    scopus 로고
    • Simultaneous determination of evodiamine and rutecarpine in rabbit plasma by LC-ESI-MS and its application to pharmacokinetics
    • Lin, C.; Pan, X.; Li, W.; Ma, J.; Pan, J.; Cai, J.; Wang, X.; Lin, G. Simultaneous determination of evodiamine and rutecarpine in rabbit plasma by LC-ESI-MS and its application to pharmacokinetics. Pharmazie 2011, 66, 920-923.
    • (2011) Pharmazie , vol.66 , pp. 920-923
    • Lin, C.1    Pan, X.2    Li, W.3    Ma, J.4    Pan, J.5    Cai, J.6    Wang, X.7    Lin, G.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.