The cardioprotection of rutaecarpine is mediated by endogenous calcitonin related-gene peptide through activation of vanilloid receptors in guinea-pig hearts

Planta Medica

Volumn 68, Issue 8, 2002, Pages 705-709

  Hu, Chang Ping ^a   Xiao, Liang ^a   Deng, Han Wu ^a   Li, Yuan Jian ^a  

^a Central South University   (China)

Author keywords

Calcitonin gene related peptide; Capsaicin; Evodia rutaecarpa; Guinea pig isolated heart; Rutaceae; Rutaecarpine; Vanilloid receptor

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE[8-37]; CAPSAZEPINE; CREATINE KINASE; RUTAECARPINE; VANILLOID RECEPTOR;

ANIMAL TISSUE; ARTICLE; CARDIOPLEGIA; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CREATINE KINASE BLOOD LEVEL; DRUG STRUCTURE; ENZYME RELEASE; GUINEA PIG; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART RATE VARIABILITY; MALE; NONHUMAN; RECEPTOR UPREGULATION; UREA CYCLE;

ALKALOIDS; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CARDIOTONIC AGENTS; CREATINE KINASE; DOSE-RESPONSE RELATIONSHIP, DRUG; EVODIA; FRUIT; GUINEA PIGS; HEART VENTRICLES; MALE; MOLECULAR STRUCTURE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION; MYOCARDIUM; PLANTS, MEDICINAL; RADIOIMMUNOASSAY; RECEPTORS, DRUG; VENTRICULAR PRESSURE;

ANIMALIA; CAVIA PORCELLUS; RUTACEAE; SUS SCROFA;

EID: 0036676755     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-33794     Document Type: Article

References (12)

1. Vasorelaxing action of rutaecarpine: Effects of rutaecarpine on calcium channel activities in vascular endothelial and smooth muscle cells
2. Antithrombotic effect of rutaecarpine, an alkaloid isolated from Evodia rutaecarpa, on platelet plug formation in in vivo experiments
3. Calcitonin gene-related peptide and tachykinins in relation to local sensory control of cardiac contractility and coronary vascular tone
4. Protective effects of calcitonin gene-related peptide (CGRP) on myocardial cell injury and calcium and magnesium contents following severe hypoxia and simulated reperfusion
5. Calcitonin gene-related peptide protects against endothelial cell damage due to oxidised low-density lipoprotein
6. Calcitonin gene-related peptide-induced preconditioning protects against ischemia-reperfusion injury in isolated rat hearts
7. Calcitonin gene-related peptide-induced preconditioning improves preservation with cardioplegia
8. The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: Possible involvement of vanilloid receptors
9. Calcitonin gene-related peptide-mediated ischemic preconditioning in the rat heart: Influence of age
10. Aggravation of myocardial infarction in the porcine heart by capsaicin-induced depletion of calcitonin gene-related peptide (CGRP)
11. Calcitonin gene-related peptide in patients with and without early reperfusion after acute myocardial infarction
12. Myocardial outflow of calcitonin gene-related peptide in relation to metabolic stress during coronary artery bypass grafting without cardiopulmonary bypass