QSAR modeling on benzo[c]phenanthridine analogues as topoisomerase i inhibitors and anti-cancer agents

Molecules

Volumn 17, Issue 5, 2012, Pages 5690-5712

  Thai, Khac Minh ^a   Bui, Quang Huynh ^a   Tran, Thanh Dao ^a   Huynh, Thi Ngoc Phuong ^a  

^a UNIVERSITY OF MEDICINE AND PHARMACY AT HO CHI MINH CITY   (Viet Nam)

Author keywords

Benzo c phenanthridine; Confidence level; Cytotoxicity; Model assessment; QSAR; Topoisomerase

Indexed keywords

ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; PHENANTHRIDINE DERIVATIVE; TOP1 PROTEIN, HUMAN;

ARTICLE; CELL SURVIVAL; CHEMICAL MODEL; CHEMISTRY; DRUG EFFECT; HUMAN; IC 50; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DNA TOPOISOMERASES, TYPE I; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; PHENANTHRIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOPOISOMERASE I INHIBITORS;

EID: 84861485138     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17055690     Document Type: Article

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