Aging reverses the role of the transient receptor potential vanilloid-1 channel in systemic inflammation from anti-inflammatory to proinflammatory

Cell Cycle

Volumn 11, Issue 2, 2012, Pages 343-349

  Wanner, Samuel P ^a,b   Garami, Andras ^a   Pakai, Eszter ^a   Oliveira, Daniela L ^a   Gavva, Narender R ^c   Coimbra, Cândido C ^b   Romanovsky, Andrej A ^a  

^a ST JOSEPH'S HOSPITAL AND MEDICAL CENTER   (United States)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^c AMGEN INC   (United States)

Author keywords

Endotoxin shock; Sepsis; Systemic inflammation; TRP channels

Indexed keywords

CYTOKINE; ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; N [4 [6 [4 (TRIFLUOROMETHYL)PHENYL] 4 PYRIMIDINYLOXY]BENZOTHIAZOL 2 YL]ACETAMIDE; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TUMOR NECROSIS FACTOR ALPHA; VANILLOID RECEPTOR 1;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HOST RESISTANCE; HYPOTHERMIA; INFECTION RESISTANCE; INFLAMMATION; MALE; MORTALITY; MOUSE; NONHUMAN; SEPSIS; SURVIVAL RATE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

MUS; RODENTIA;

EID: 84856084105     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.11.2.18772     Document Type: Article

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