Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage

Journal of Investigative Dermatology

Volumn 131, Issue 4, 2011, Pages 857-864

  Bilousova, Ganna ^a,b   Chen, Jiang ^a,b   Roop, Dennis R ^a,b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; COLLAGEN TYPE 4; RETINOIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; HAIR FOLLICLE; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEBACEOUS GLAND; SKIN APPENDAGE;

EID: 79952773623     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2010.364     Document Type: Article

References (41)

1. Aberdam E, Barak E, Rouleau M et al. (2008) A pure population of ecto-dermal cells derived from human embryonic stem cells. Stem Cells 26:440-4 (Pubitemid 351413604)
2. Aoki N, Sawada S, Rogers MA et al. (2001) A novel type II cytokeratin, mK6irs, is expressed in the Huxley and Henle layers of the mouse inner root sheath. J Invest Dermatol 116:359-65 (Pubitemid 32202899)
3. Arin MJ, Longley MA, Wang XJ et al. (2001) Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders. J Cell Biol 152:645-9 (Pubitemid 34280245)
4. Bernstein ID, Andrews RG, Rowley S (1994) Isolation of human hemato-poietic stem cells. Blood Cells 20:15-23
5. Bickenbach JR, Chism E (1998) Selection and extended growth of murine epidermal stem cells in culture. Exp Cell Res 244:184-95 (Pubitemid 28480866)
6. Cao T, Longley MA, Wang XJ et al. (2001) An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy. J Cell Biol 152:651-6 (Pubitemid 34280246)
7. Challita PM, Kohn DB (1994) Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo. Proc Natl Acad Sci USA 91:2567-71 (Pubitemid 24139388)
8. Civin CI, Loken MR (1987) Cell surface antigens on human marrow cells: dissection of hematopoietic development using monoclonal antibodies and multiparameter flow cytometry. Int J Cell Cloning 5:267-88 (Pubitemid 17124721)
9. De Luca M, Pellegrini G, Mavilio F (2009) Gene therapy of inherited skin adhesion disorders: a critical overview. Br J Dermatol 161:19-24
10. Dimos JT, Rodolfa KT, Niakan KK et al. (2008) Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 321:1218-21
11. Evans MJ, Kaufman MH (1981) Establishment in culture of pluripotential cells from mouse embryos. Nature 292:154-6 (Pubitemid 11050741)
12. Gai H, Leung EL, Costantino PD et al. (2009) Generation and characterization of functional cardiomyocytes using induced pluripotent stem cells derived from human fibroblasts. Cell Biol Int 33:1184-93
13. Green H, Easley K, Iuchi S (2003) Marker succession during the development of keratinocytes from cultured human embryonic stem cells. Proc Natl Acad Sci USA 100:15625-30 (Pubitemid 38021040)
14. Guenou H, Nissan X, Larcher F et al. (2009) Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study. Lancet 374:1745-53
15. Hanna J, Wernig M, Markoulaki S et al. (2007) Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 318:1920-3
16. Heid HW, Moll R, Schwetlick I et al. (1998) Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases. Cell Tissue Res 294:309-21 (Pubitemid 28486407)
17. Huangfu D, Osafune K, Maehr R et al. (2008) Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat Biotechnol 26:1269-75
18. Kim D, Kim CH, Moon JI et al. (2009) Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4:472-6
19. Kobayashi T, Yoshioka R, Shiraishi A et al. (2009) New technique for culturing corneal epithelial cells of normal mice. Mol Vis 15:1589-93
20. Koster MI, Kim S, Mills AA et al. (2004) p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev 18:126-31 (Pubitemid 38141780)
21. Lichti U, Anders J, Yuspa SH (2008) Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice. Nat Protoc 3:799-810 (Pubitemid 351639024)
22. Mavilio F, Pellegrini G, Ferrari S et al. (2006) Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells. Nat Med 12:1397-402 (Pubitemid 44924498)
23. Mehrel T, Hohl D, Rothnagel JA et al. (1990) Identification of a major keratinocyte cell envelope protein, loricrin. Cell 61:1103-12
24. Metallo CM, Ji L, de Pablo JJ et al. (2008) Retinoic acid and bone morphogenetic protein signaling synergize to efficiently direct epithelial differentiation of human embryonic stem cells. Stem Cells 26:372-80 (Pubitemid 351413597)
25. Mills AA, Zheng B, Wang XJ et al. (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398:708-13 (Pubitemid 29197649)
26. Ochiya T, Yamamoto Y, Banas A (2010) Commitment of stem cells into functional hepatocytes. Differentiation 79:65-73
27. Okita K, Ichisaka T, Yamanaka S (2007) Generation of germline-competent induced pluripotent stem cells. Nature 448:313-7 (Pubitemid 47080336)
28. Roop DR, Cheng CK, Titterington L et al. (1984) Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies. J Biol Chem 259:8037-40 (Pubitemid 14090536)
29. Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663-76 (Pubitemid 44233629)
30. Tamai K, Kaneda Y, Uitto J (2009) Molecular therapies for heritable blistering diseases. Trends Mol Med 15:285-92
31. Taura D, Noguchi M, Sone M et al. (2009) Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells. FEBS Lett 583:1029-33
32. Uchida N, Fleming WH, Alpern EJ et al. (1993) Heterogeneity of hemato-poietic stem cells. Curr Opin Immunol 5:177-84
33. Uitto J (2009) Progress in heritable skin diseases: translational implications of mutation analysis and prospects of molecular therapies. Acta Derm Venereol 89:228-35
34. Wernig M, Meissner A, Foreman R et al. (2007) In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448:318-24 (Pubitemid 47080337)
35. Wernig M, Zhao JP, Pruszak J et al. (2008) Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc Natl Acad Sci USA 105:5856-61 (Pubitemid 351758462)
36. Wojcik SM, Longley MA, Roop DR (2001) Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b. J Cell Biol 154:619-30 (Pubitemid 34286166)
37. Yu J, Hu K, Smuga-Otto K et al. (2009) Human induced pluripotent stem cells free of vector and transgene sequences. Science 324:797-801
38. Yu J, Vodyanik MA, Smuga-Otto K et al. (2007) Induced pluripotent stem cell lines derived from human somatic cells. Science 318:1917-20
39. Yuspa SH, Kilkenny AE, Steinert PM et al. (1989) Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro. J Cell Biol 109:1207-17 (Pubitemid 19220102)
40. Zhou J, Zhang Y, Lin Q et al. (2010) Embryoid bodies formation and differentiation from mouse embryonic stem cells in collagen/Matrigel scaffolds. J Genet Genomics 37:451-60
41. Zhou W, Freed CR (2009) Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells. Stem Cells 27:2667-74