Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndrome

Human Molecular Genetics

Volumn 21, Issue 17, 2012, Pages 3825-3834

  Andrade, Luciana Nogueira de Sousa ^a,b,c   Nathanson, Jason L ^b   Yeo, Gene W ^b   Menck, Carlos Frederico Martins ^c   Muotri, Alysson Renato ^a,b  

^a RADY CHILDREN'S HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ARRDC3 PROTEIN; ARRDC4 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; ERCC 6 PROTEIN; ESTERASE; HISTONE H2AX; LIN28 PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN; PROTEIN P53; REACTIVE OXYGEN METABOLITE; STAGE SPECIFIC EMBRYO ANTIGEN 4; THIOREDOXIN INTERACTING PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CELL VIABILITY; COCKAYNE SYNDROME; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EMBRYO; EMBRYONIC STEM CELL; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; NUCLEAR REPROGRAMMING; OXIDATIVE STRESS; PHENOTYPE; PLURIPOTENT STEM CELL; PREMATURE AGING; PRIORITY JOURNAL; SKIN FIBROBLAST; UPREGULATION;

AGING, PREMATURE; CELL DEATH; CELL HYPOXIA; CELL SURVIVAL; CLONE CELLS; COCKAYNE SYNDROME; DNA DAMAGE; GENE EXPRESSION REGULATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MODELS, BIOLOGICAL; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84865070766     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds211     Document Type: Article

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