-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin, D. M.; Bray, F.; Ferlay, J.; Pisani, P. Global cancer statistics, 2002. CA Cancer J. Clin. 2005, 55, 74-108.
-
(2005)
CA Cancer J. Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
2
-
-
34250020201
-
Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
-
El-Serag, H. B.; Rudolph, K. L. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007, 132, 2557-2576.
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
3
-
-
84855792427
-
Cancer statistics, 2012
-
Siegal, R.; Naishadham, D.; Jemal, A. Cancer statistics, 2012. CA Cancer J. Clin. 2012, 62, 10-29.
-
(2012)
CA Cancer J. Clin
, vol.62
, pp. 10-29
-
-
Siegal, R.1
Naishadham, D.2
Jemal, A.3
-
4
-
-
75149163334
-
Aging of hepatitis C virus (HCV)-infected persons in the United States: A multiple cohort model of HCV prevalence and disease progression
-
Davis, G. L.; Alter, M. J.; El-Serag, H.; Poynard, T.; Jennings, L. W. Aging of hepatitis C virus (HCV)-infected persons in the United States: a multiple cohort model of HCV prevalence and disease progression. Gastroenterology 2010, 138, 513-521.
-
(2010)
Gastroenterology
, vol.138
, pp. 513-521
-
-
Davis, G.L.1
Alter, M.J.2
El-Serag, H.3
Poynard, T.4
Jennings, L.W.5
-
5
-
-
0021680014
-
Relevance of nitrosamines to human cancer
-
Bartsch, H.; Montesano, R. Relevance of nitrosamines to human cancer. Carcinogenesis 1984, 5, 1381-1393.
-
(1984)
Carcinogenesis
, vol.5
, pp. 1381-1393
-
-
Bartsch, H.1
Montesano, R.2
-
6
-
-
0141491273
-
Hepatocellular carcinoma
-
Llovet, J. M.; Burroughs, A.; Bruix, J. Hepatocellular carcinoma. Lancet 2003, 362, 1907-1917.
-
(2003)
Lancet
, vol.362
, pp. 1907-1917
-
-
Llovet, J.M.1
Burroughs, A.2
Bruix, J.3
-
7
-
-
7044253317
-
Chemoprevention of hepatocellular carcinoma in aflatoxin endemic areas
-
Kensler, T. W.; Egner, P. A.; Wang, J. B.; Zhu, Y. R.; Zhang, B. C.; Lu, P. X.; Chen, J. G.; Qian, G. S.; Kuang, S. Y.; Jackson, P. E.; Gange, S. J.; Jacobson, L. P.; Muñoz, A.; Groopman, J. D. Chemoprevention of hepatocellular carcinoma in aflatoxin endemic areas. Gastroenterology 2004, 127, S310-318.
-
(2004)
Gastroenterology
, vol.127
-
-
Kensler, T.W.1
Egner, P.A.2
Wang, J.B.3
Zhu, Y.R.4
Zhang, B.C.5
Lu, P.X.6
Chen, J.G.7
Qian, G.S.8
Kuang, S.Y.9
Jackson, P.E.10
Gange, S.J.11
Jacobson, L.P.12
Muñoz, A.13
Groopman, J.D.14
-
8
-
-
67650938576
-
Hepatocellular carcinoma-epidemiological trends and risk factors
-
Schütte, K.; Bornschein, J.; Malfertheiner, P. Hepatocellular carcinoma-epidemiological trends and risk factors. Dig. Dis. 2009, 27, 80-92.
-
(2009)
Dig. Dis
, vol.27
, pp. 80-92
-
-
Schütte, K.1
Bornschein, J.2
Malfertheiner, P.3
-
9
-
-
28844480321
-
Management of hepatocellular carcinoma
-
Bruix, J.; Sherman, M. Management of hepatocellular carcinoma. Hepatology 2005, 42, 1208-1236.
-
(2005)
Hepatology
, vol.42
, pp. 1208-1236
-
-
Bruix, J.1
Sherman, M.2
-
10
-
-
77950612887
-
Where are we in the chemoprevention of hepatocellular carcinoma?
-
Lu S. C. Where are we in the chemoprevention of hepatocellular carcinoma? Hepatology 2010, 51, 734-736.
-
(2010)
Hepatology
, vol.51
, pp. 734-736
-
-
Lu, S.C.1
-
11
-
-
77957603190
-
Hepatocellular carcinoma: Consensus recommendations of the National Cancer Institute Clinical Trials Planning Meeting
-
Thomas, M. B.; Jaffe, D.; Choti, M. M.; Belghiti, J.; Curley, S.; Fong, Y.; Gores, G.; Kerlan, R.; Merle, P.; O'Neil, B.; Poon, R.; Schwartz, L.; Tepper, J.; Yao, F.; Haller, D.; Mooney, M.; Venook A. Hepatocellular carcinoma: consensus recommendations of the National Cancer Institute Clinical Trials Planning Meeting. J. Clin. Oncol. 2010, 28, 3994-4005.
-
(2010)
J. Clin. Oncol
, vol.28
, pp. 3994-4005
-
-
Thomas, M.B.1
Jaffe, D.2
Choti, M.M.3
Belghiti, J.4
Curley, S.5
Fong, Y.6
Gores, G.7
Kerlan, R.8
Merle, P.9
O'Neil, B.10
Poon, R.11
Schwartz, L.12
Tepper, J.13
Yao, F.14
Haller, D.15
Mooney, M.16
Venook, A.17
-
12
-
-
79551525006
-
Chemoprevention of hepatocellular carcinoma in chronic hepatitis C
-
Morgan T. R. Chemoprevention of hepatocellular carcinoma in chronic hepatitis C. Recent Results Cancer Res. 2011, 188, 85-99.
-
(2011)
Recent Results Cancer Res
, vol.188
, pp. 85-99
-
-
Morgan, T.R.1
-
13
-
-
33749261599
-
Angiogenesis and antiangiogenic therapy in hepatocellular carcinoma
-
Pang, R., Poon, R. T. P. Angiogenesis and antiangiogenic therapy in hepatocellular carcinoma. Cancer Lett. 2006, 242, 151-167.
-
(2006)
Cancer Lett
, vol.242
, pp. 151-167
-
-
Pang, R.1
Poon, R.T.P.2
-
14
-
-
77958088824
-
Angiogenesis: Multiple masks in hepatocellular carcinoma and liver regeneration
-
Chen, J. A.; Shi, M.; Li, J. Q.; Qian, C. N. Angiogenesis: multiple masks in hepatocellular carcinoma and liver regeneration. Hepatol. Int. 2010, 4, 537-47.
-
(2010)
Hepatol. Int
, vol.4
, pp. 537-547
-
-
Chen, J.A.1
Shi, M.2
Li, J.Q.3
Qian, C.N.4
-
15
-
-
78650768221
-
Angiogenesis in chronic liver disease and its complications
-
Coulon, S.; Heindryckx, F.; Geerts, A.; Van Steenkiste, C.; Colle, I.; Van Vlierberghe, H. Angiogenesis in chronic liver disease and its complications. Liver Int. 2011, 31, 146-162.
-
(2011)
Liver Int
, vol.31
, pp. 146-162
-
-
Coulon, S.1
Heindryckx, F.2
Geerts, A.3
van Steenkiste, C.4
Colle, I.5
van Vlierberghe, H.6
-
16
-
-
0028827625
-
Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo
-
Asahara, T.; Bauters, C.; Zheng, L. P.; Takeshita, S.; Bunting, S.; Ferrara, N.; Symes, J. F.; Isner, J. M. Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo. Circulation 1995, 92, II365-371.
-
(1995)
Circulation
, vol.92
-
-
Asahara, T.1
Bauters, C.2
Zheng, L.P.3
Takeshita, S.4
Bunting, S.5
Ferrara, N.6
Symes, J.F.7
Isner, J.M.8
-
17
-
-
3042761526
-
Angiogenesis in hepatocellular carcinoma: The retrospectives and perspectives
-
Sung, H. S.; Tang, Z. Y. Angiogenesis in hepatocellular carcinoma: the retrospectives and perspectives. J. Cancer Res. Clin. Oncol. 2004, 130, 307-319.
-
(2004)
J. Cancer Res. Clin. Oncol
, vol.130
, pp. 307-319
-
-
Sung, H.S.1
Tang, Z.Y.2
-
18
-
-
33645880784
-
Current status and perspective of antiangiogenic therapy for cancer: Hepatocellular carcinoma
-
Tanaka, S.; Arii, S. Current status and perspective of antiangiogenic therapy for cancer: hepatocellular carcinoma. Int. J. Clin. Oncol. 2006, 11, 82-89.
-
(2006)
Int. J. Clin. Oncol
, vol.11
, pp. 82-89
-
-
Tanaka, S.1
Arii, S.2
-
19
-
-
33748147734
-
Angiogenesis and anti-angiogenesis in hepatocellular carcinoma
-
Ribatti, D.; Vacca, A.; Nico, B.; Sansonno, D.; Dammacco, F. Angiogenesis and anti-angiogenesis in hepatocellular carcinoma. Cancer Treat. Rev. 2006, 32, 437-444.
-
(2006)
Cancer Treat. Rev
, vol.32
, pp. 437-444
-
-
Ribatti, D.1
Vacca, A.2
Nico, B.3
Sansonno, D.4
Dammacco, F.5
-
20
-
-
59749083509
-
New strategy of antiangiogenic therapy for hepatocellular carcinoma
-
Wu, X. Z. New strategy of antiangiogenic therapy for hepatocellular carcinoma. Neoplasma 2008, 6, 472-481.
-
(2008)
Neoplasma
, vol.6
, pp. 472-481
-
-
Wu, X.Z.1
-
21
-
-
80052976123
-
Liver cancer: Targeted future options
-
Pircher, A.; Medinger, M.; Drevs, J. Liver cancer: targeted future options. World J. Hepatol. 2011, 27, 38-44.
-
(2011)
World J. Hepatol
, vol.27
, pp. 38-44
-
-
Pircher, A.1
Medinger, M.2
Drevs, J.3
-
22
-
-
0004623809
-
Increased expression of vascular endothelial growth factor and angiogenesis in the early stage of multistep hepatocarcinogenesis
-
Park, Y. N.; Kim, Y. B.; Yang, K. M.; Park, C. Increased expression of vascular endothelial growth factor and angiogenesis in the early stage of multistep hepatocarcinogenesis. Arch. Pathol. Lab. Med. 2000, 124, 1061-1065.
-
(2000)
Arch. Pathol. Lab. Med
, vol.124
, pp. 1061-1065
-
-
Park, Y.N.1
Kim, Y.B.2
Yang, K.M.3
Park, C.4
-
23
-
-
34447106967
-
Hypoxia-inducible factor-1alpha expression in experimental cirrhosis: Correlation with vascular endothelial growth factor expression and angiogenesis
-
Bozova, S.; Elpek, G. O. Hypoxia-inducible factor-1alpha expression in experimental cirrhosis: correlation with vascular endothelial growth factor expression and angiogenesis. APMIS 2007, 115, 795-801.
-
(2007)
APMIS
, vol.115
, pp. 795-801
-
-
Bozova, S.1
Elpek, G.O.2
-
24
-
-
66649084445
-
Expression and correlation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor and microvessel density in experimental rat hepatocarcinogenesis
-
Wang, W.; Xu, G.L.; Jia, W. D.; Wang, Z. H.; Li, J. S.; Ma, J. L.; Ge, Y. S.; Xie, S. X.; Yu, J. H. Expression and correlation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor and microvessel density in experimental rat hepatocarcinogenesis. J. Int. Med. Res. 2009, 37, 417-425.
-
(2009)
J. Int. Med. Res
, vol.37
, pp. 417-425
-
-
Wang, W.1
Xu, G.L.2
Jia, W.D.3
Wang, Z.H.4
Li, J.S.5
Ma, J.L.6
Ge, Y.S.7
Xie, S.X.8
Yu, J.H.9
-
25
-
-
84872584969
-
Angioprevention is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis
-
Bishayee, A.; Petit, D. M.; Samtani, K. Angioprevention is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis. J. Carcinog. Mutagen. 2010, 1, 102.
-
(2010)
J. Carcinog. Mutagen
, vol.1
, pp. 102
-
-
Bishayee, A.1
Petit, D.M.2
Samtani, K.3
-
26
-
-
0036136731
-
'Angioprevention': Angiogenesis is a common and key target for cancer chemopreventive agents
-
Tosetti, F.; Ferrari, N.; de Flora, S.; Albini, A. 'Angioprevention': angiogenesis is a common and key target for cancer chemopreventive agents. FASEB J. 2002, 16, 2-16.
-
(2002)
FASEB J
, vol.16
, pp. 2-16
-
-
Tosetti, F.1
Ferrari, N.2
de Flora, S.3
Albini, A.4
-
27
-
-
0032998680
-
Microvessel density of hepatocellular carcinoma: Its relationship with prognosis
-
Sun, H. C.; Tang, Z. Y.; Li, X.M.; Zhou, Y. N.; Sun, B. R.; Ma, Z. C. Microvessel density of hepatocellular carcinoma: its relationship with prognosis. J. Cancer Res. Clin. Oncol. 1999, 125, 419-426.
-
(1999)
J. Cancer Res. Clin. Oncol
, vol.125
, pp. 419-426
-
-
Sun, H.C.1
Tang, Z.Y.2
Li, X.M.3
Zhou, Y.N.4
Sun, B.R.5
Ma, Z.C.6
-
28
-
-
33947590737
-
Vasculogenic mimicry is associated with high tumor grade, invasion and metastasis, and short survival in patients with hepatocellular carcinoma
-
Sun, B.; Zhang, S.; Zhang, D.; Du, J.; Guo, H.; Zhao, X.; Zhang, W.; Hao, X. Vasculogenic mimicry is associated with high tumor grade, invasion and metastasis, and short survival in patients with hepatocellular carcinoma. Oncol. Rep. 2006, 16, 693-698.
-
(2006)
Oncol. Rep
, vol.16
, pp. 693-698
-
-
Sun, B.1
Zhang, S.2
Zhang, D.3
Du, J.4
Guo, H.5
Zhao, X.6
Zhang, W.7
Hao, X.8
-
29
-
-
50849120002
-
Jr. VEGF receptor protein-kinases: Structure and regulation
-
Roskoski, R. Jr. VEGF receptor protein-kinases: structure and regulation. Biochem. Biophys Res. Commun. 2008, 375, 287-291.
-
(2008)
Biochem. Biophys Res. Commun
, vol.375
, pp. 287-291
-
-
Roskoski, R.1
-
30
-
-
70350507211
-
Vascular endothelial growth factor in the management of hepatocellular carcinoma
-
Kaseb, A. O.; Hanbali, A.; Cotant, M.; Hassan, M. M.; Wollner, I.; Philip, P. A. Vascular endothelial growth factor in the management of hepatocellular carcinoma. Cancer 2009, 115, 4895-4906.
-
(2009)
Cancer
, vol.115
, pp. 4895-4906
-
-
Kaseb, A.O.1
Hanbali, A.2
Cotant, M.3
Hassan, M.M.4
Wollner, I.5
Philip, P.A.6
-
31
-
-
79958121732
-
VEGF/VEGFR pathway inhibitors as anti-angiogenic agents
-
Sharma, P. S.; Sharma, R.; Tyagi, T. VEGF/VEGFR pathway inhibitors as anti-angiogenic agents. Curr. Cancer Drug Targets 2011, 11, 624-653.
-
(2011)
Curr. Cancer Drug Targets
, vol.11
, pp. 624-653
-
-
Sharma, P.S.1
Sharma, R.2
Tyagi, T.3
-
32
-
-
67650305795
-
Targeting angiogenesis in hepatocellular carcinoma: Focus of VEGR and becacizumab
-
Finn, R. S.; Zhu, A. X. Targeting angiogenesis in hepatocellular carcinoma: focus of VEGR and becacizumab. Expert. Rev. Anticancer Ther. 2009, 9, 503-509.
-
(2009)
Expert. Rev. Anticancer Ther
, vol.9
, pp. 503-509
-
-
Finn, R.S.1
Zhu, A.X.2
-
33
-
-
77950960449
-
Further pharmacological and genetic evidence for the efficacy of PIGF inhibition in cancer and eye disease
-
Van de Veire, S.; Stalmans, I.; Heindryckx, F.; Oura, H.; Tijeras-Raballand, A.; Schmidt, T.; Loges, S.; Albrecht, I.; Jonckx, B.; Vinckier, S.; Van Steenkiste, C.; Tugues, S.; Rolny, C.; De Mol, M.; Dettori, D.; Hainaud, P.; Coenegrachts, L.; Contreres, J. O.; Van Bergen, T.; Cuervo, H.; Xiao, W. H.; Le Henaff, C.; Buysschaert, I.; Kharabi Masouleh, B.; Geerts, A.; Schomber, T.; Bonnin, P.; Lambert, V.; Haustraete, J.; Zacchigna, S.; Rakic, J. M.; Jiménez, W.; Noël, A.; Giacca, M.; Colle, I.; Foidart, J. M.; Tobelem, G.; Morales-Ruiz, M.; Vilar, J.; Maxwell, P.; Vinores, S. A.; Carmeliet, G.; Dewerchin, M.; Claesson-Welsh, L.; Dupuy, E.; Van Vlierberghe, H.; Christofori, G.; Mazzone, M.; Detmar, M.; Collen, D.; Carmeliet, P. Further pharmacological and genetic evidence for the efficacy of PIGF inhibition in cancer and eye disease. Cell 2010, 141, 178-190.
-
(2010)
Cell
, vol.141
, pp. 178-190
-
-
van de Veire, S.1
Stalmans, I.2
Heindryckx, F.3
Oura, H.4
Tijeras-Raballand, A.5
Schmidt, T.6
Loges, S.7
Albrecht, I.8
Jonckx, B.9
Vinckier, S.10
van Steenkiste, C.11
Tugues, S.12
Rolny, C.13
de Mol, M.14
Dettori, D.15
Hainaud, P.16
Coenegrachts, L.17
Contreres, J.O.18
van Bergen, T.19
Cuervo, H.20
Xiao, W.H.21
Le Henaff, C.22
Buysschaert, I.23
Kharabi Masouleh, B.24
Geerts, A.25
Schomber, T.26
Bonnin, P.27
Lambert, V.28
Haustraete, J.29
Zacchigna, S.30
Rakic, J.M.31
Jiménez, W.32
Noël, A.33
Giacca, M.34
Colle, I.35
Foidart, J.M.36
Tobelem, G.37
Morales-Ruiz, M.38
Vilar, J.39
Maxwell, P.40
Vinores, S.A.41
Carmeliet, G.42
Dewerchin, M.43
Claesson-Welsh, L.44
Dupuy, E.45
van Vlierberghe, H.46
Christofori, G.47
Mazzone, M.48
Detmar, M.49
Collen, D.50
Carmeliet, P.51
more..
-
35
-
-
0030961006
-
Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteosome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
-
Salceda, S.; Caro, J. Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteosome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J. Biol. Chem. 1997, 272, 22642-22647.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 22642-22647
-
-
Salceda, S.1
Caro, J.2
-
36
-
-
0036359548
-
Hypoxia-a key regulator in angiogenesis
-
Harris, A. L. Hypoxia-a key regulator in angiogenesis. Nat. Rev. Cancer 2002, 2, 38-47.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
37
-
-
33745138232
-
Regulation of angiogenesis by hypoxiainducible factor 1
-
Hirota, K.; Semenza, G. L. Regulation of angiogenesis by hypoxiainducible factor 1. Crit. Rev. Oncol. Hematol. 2006, 59, 15-26.
-
(2006)
Crit. Rev. Oncol. Hematol
, vol.59
, pp. 15-26
-
-
Hirota, K.1
Semenza, G.L.2
-
38
-
-
0034641615
-
Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex
-
Kamura, T.; Sato, S.; Iwai, K.; Czyzyk-Krzeska, M.; Conaway, R. C.; Conaway, J. W. Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex. Proc. Natl. Acad. Sci. USA 2000, 97, 10430-10435.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10430-10435
-
-
Kamura, T.1
Sato, S.2
Iwai, K.3
Czyzyk-Krzeska, M.4
Conaway, R.C.5
Conaway, J.W.6
-
39
-
-
0035955663
-
Regulation of the hypoxia-inducible factor 1alpha by the inflammatory mediators nitric oxide and tumor necrosis factor-alpha in contrast to desferroxamine and phenylarsine oxide
-
Sandau, K. B.; Zhou, J.; Kietzmann, T.; Brüne, B. Regulation of the hypoxia-inducible factor 1alpha by the inflammatory mediators nitric oxide and tumor necrosis factor-alpha in contrast to desferroxamine and phenylarsine oxide. J. Biol. Chem. 2001, 276, 39805-38911.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 38911-39805
-
-
Sandau, K.B.1
Zhou, J.2
Kietzmann, T.3
Brüne, B.4
-
40
-
-
3442881606
-
The potential role of hypoxia inducible factor 1in tumor progression after hypoxia and chemotherapy in hepatocellular carcinoma
-
Yang, Z. F.; Poon, R. T.; To, J.; Ho, D. W.; Fan, S. T. The potential role of hypoxia inducible factor 1in tumor progression after hypoxia and chemotherapy in hepatocellular carcinoma. Cancer Res. 2004, 64, 5496-5503.
-
(2004)
Cancer Res
, vol.64
, pp. 5496-5503
-
-
Yang, Z.F.1
Poon, R.T.2
To, J.3
Ho, D.W.4
Fan, S.T.5
-
41
-
-
17144364359
-
Expression of hypoxia-inducible factor 1and vascular endothelial growth factor in hepatocellular carcinoma: Impact on neovascularization and survival
-
Huang, G.; Yang, L.; Lu, W. Expression of hypoxia-inducible factor 1and vascular endothelial growth factor in hepatocellular carcinoma: impact on neovascularization and survival. World J. Gastroenterol. 2005, 11, 1705-1708.
-
(2005)
World J. Gastroenterol
, vol.11
, pp. 1705-1708
-
-
Huang, G.1
Yang, L.2
Lu, W.3
-
42
-
-
0032899694
-
Vascular endothelial growth factor production in peritoneal macrophages of cirrhotic patients: Regulation by cytokines and bacterial lipopolysaccharide
-
Pérez-Ruiz, M.; Ros, J.; Morales-Ruiz, M.; Navasa, M.; Colmenero, J.; Ruiz-del-Arbol, L.; Cejudo, P.; Clária, J.; Rivera, F.; Arroyo, V.; Rodés, J.; Jiménez, W. Vascular endothelial growth factor production in peritoneal macrophages of cirrhotic patients: regulation by cytokines and bacterial lipopolysaccharide. Hepatology 1999, 29, 1057-1063.
-
(1999)
Hepatology
, vol.29
, pp. 1057-1063
-
-
Pérez-Ruiz, M.1
Ros, J.2
Morales-Ruiz, M.3
Navasa, M.4
Colmenero, J.5
Ruiz-del-Arbol, L.6
Cejudo, P.7
Clária, J.8
Rivera, F.9
Arroyo, V.10
Rodés, J.11
Jiménez, W.12
-
43
-
-
0035256554
-
Expression and function of interleukin-8 in human hepatocellular carcinoma
-
Akiba, J.; Yano, H.; Ogasawara, S.; Higaki, K.; Kojiro, M. Expression and function of interleukin-8 in human hepatocellular carcinoma. Int. J. Oncol. 2001, 18, 257-264.
-
(2001)
Int. J. Oncol
, vol.18
, pp. 257-264
-
-
Akiba, J.1
Yano, H.2
Ogasawara, S.3
Higaki, K.4
Kojiro, M.5
-
44
-
-
25144507526
-
Interleukin 8 in human hepatocellular carcinoma correlates with cancer cell invasion of vessels but not with tumor angiogenesis
-
Kubo, F.; Ueno, S.; Hiwatashi, K.; Sakoda, M.; Kawaida, K.; Nuruki, K.; Aikou, T. Interleukin 8 in human hepatocellular carcinoma correlates with cancer cell invasion of vessels but not with tumor angiogenesis. Ann. Surg. Oncol. 2005, 12, 800-807.
-
(2005)
Ann. Surg. Oncol
, vol.12
, pp. 800-807
-
-
Kubo, F.1
Ueno, S.2
Hiwatashi, K.3
Sakoda, M.4
Kawaida, K.5
Nuruki, K.6
Aikou, T.7
-
45
-
-
31544468915
-
Cyclooxygenase-2 in hepatocellular carcinoma
-
Wu, T. Cyclooxygenase-2 in hepatocellular carcinoma. Cancer Treat. Rev. 2006, 32, 28-44.
-
(2006)
Cancer Treat. Rev
, vol.32
, pp. 28-44
-
-
Wu, T.1
-
46
-
-
33845875713
-
Potential involvement of the cyclooxygenase-2 pathway in hepatocellular carcinoma-associated angiogenesis
-
Zhao, Q. T.; Yue, S. Q.; Cui, Z.; Wang, Q.; Cui, X.; Zhai, H. H.; Zhang, L. H.; Dou, K. F. Potential involvement of the cyclooxygenase-2 pathway in hepatocellular carcinoma-associated angiogenesis. Life Sci. 2007, 80, 484-492.
-
(2007)
Life Sci
, vol.80
, pp. 484-492
-
-
Zhao, Q.T.1
Yue, S.Q.2
Cui, Z.3
Wang, Q.4
Cui, X.5
Zhai, H.H.6
Zhang, L.H.7
Dou, K.F.8
-
47
-
-
1842852639
-
Cyclooxygenase-2 pathway correlates with vascular endothelial growth factor expression and tumor angiogenesis in hepatitis B virus-associated hepatocellular carcinoma
-
Cheng, A. S.; Chan, H. L.; To, K. F.; Leung, W. K.; Chan, K. K.; Liew, C. T.; Sung, J. J. Cyclooxygenase-2 pathway correlates with vascular endothelial growth factor expression and tumor angiogenesis in hepatitis B virus-associated hepatocellular carcinoma. Int. J. Oncol. 2004, 24, 853-860.
-
(2004)
Int. J. Oncol
, vol.24
, pp. 853-860
-
-
Cheng, A.S.1
Chan, H.L.2
To, K.F.3
Leung, W.K.4
Chan, K.K.5
Liew, C.T.6
Sung, J.J.7
-
48
-
-
17144403485
-
Tumor cyclooxygenase-2 levels correlate with tumor invasiveness in human hepatocellular carcinoma
-
Tang, T. C.; Poon, R. T.; Lau, C. P.; Xie, D.; Fan, S. T. Tumor cyclooxygenase-2 levels correlate with tumor invasiveness in human hepatocellular carcinoma. World J. Gastroenterol. 2005, 11, 1896-1902.
-
(2005)
World J. Gastroenterol
, vol.11
, pp. 1896-1902
-
-
Tang, T.C.1
Poon, R.T.2
Lau, C.P.3
Xie, D.4
Fan, S.T.5
-
49
-
-
33751423908
-
Expression of inducible nitric oxide (NO) synthase but not prevention by its gene ablation of hepatocarcinogenesis with fibrosis caused by a choline-deficient, L-amino acid-defined diet in rats and mice
-
Denda, A.; Kitayama, W.; Kishida, H.; Murata, N.; Tamura, K.; Kusuoka, O.; Tsutsumi, M.; Nishikawa, F.; Kita, E.; Nakae, D.; Konishi, Y.; Kuniyasu, H. Expression of inducible nitric oxide (NO) synthase but not prevention by its gene ablation of hepatocarcinogenesis with fibrosis caused by a choline-deficient, L-amino acid-defined diet in rats and mice. Nitric Oxide 2007, 16, 164-176.
-
(2007)
Nitric Oxide
, vol.16
, pp. 164-176
-
-
Denda, A.1
Kitayama, W.2
Kishida, H.3
Murata, N.4
Tamura, K.5
Kusuoka, O.6
Tsutsumi, M.7
Nishikawa, F.8
Kita, E.9
Nakae, D.10
Konishi, Y.11
Kuniyasu, H.12
-
50
-
-
49649098848
-
Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease
-
Calvisi, D. F.; Pinna, F.; Ladu, S.; Pellegrino, R.; Muroni, M. R.; Simile, M. M.; Frau, M.; Tomasi, M. L.; De Miglio, M. R.; Seddaiu, M. A.; Daino, L.; Sanna, V.; Feo, F.; Pascale, R. M. Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease. Carcinogenesis 2008, 29, 1639-1647.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1639-1647
-
-
Calvisi, D.F.1
Pinna, F.2
Ladu, S.3
Pellegrino, R.4
Muroni, M.R.5
Simile, M.M.6
Frau, M.7
Tomasi, M.L.8
de Miglio, M.R.9
Seddaiu, M.A.10
Daino, L.11
Sanna, V.12
Feo, F.13
Pascale, R.M.14
-
51
-
-
0034906314
-
Coexpression of inducible nitric oxide synthase and COX 2 in hepatocellular carcinoma and surrounding liver: Possible involvement of COX-2 in the angiogenesis of hepatitis C viruspositive cases
-
Rahman, M. A.; Dhar, D. K.; Yamaguchi, E.; Maruyama, S.; Sato, T.; Hayashi, H.; Ono, T.; Yamanoi, A.; Kohno, H.; Nagasue, N. Coexpression of inducible nitric oxide synthase and COX 2 in hepatocellular carcinoma and surrounding liver: possible involvement of COX-2 in the angiogenesis of hepatitis C viruspositive cases. Clin. Cancer Res. 2001, 7, 1325-1332.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 1325-1332
-
-
Rahman, M.A.1
Dhar, D.K.2
Yamaguchi, E.3
Maruyama, S.4
Sato, T.5
Hayashi, H.6
Ono, T.7
Yamanoi, A.8
Kohno, H.9
Nagasue, N.10
-
52
-
-
33746036817
-
Clinical value of apoptosis and angiogenesis factors in estimating the prognosis of hepatocellular carcinoma
-
Guo, R. P.; Zhong, C.; Shi, M.; Zhang, C. Q.; Wei, W.; Zhang, Y. Q.; Li, J. Q. Clinical value of apoptosis and angiogenesis factors in estimating the prognosis of hepatocellular carcinoma. J. Cancer Res. Clin. Oncol. 2006, 132, 547-555.
-
(2006)
J. Cancer Res. Clin. Oncol
, vol.132
, pp. 547-555
-
-
Guo, R.P.1
Zhong, C.2
Shi, M.3
Zhang, C.Q.4
Wei, W.5
Zhang, Y.Q.6
Li, J.Q.7
-
53
-
-
4043104624
-
The role of angiostatin, vascular endothelial growth factor, matrix metalloproteinase 9 and 12 in the angiogenesis of hepatocellular carcinoma
-
Kim, S.; Park, H. S.; Son, H. J.; Moon, W. S. The role of angiostatin, vascular endothelial growth factor, matrix metalloproteinase 9 and 12 in the angiogenesis of hepatocellular carcinoma. Korean J. Hepatol. 2004, 10, 62-72.
-
(2004)
Korean J. Hepatol
, vol.10
, pp. 62-72
-
-
Kim, S.1
Park, H.S.2
Son, H.J.3
Moon, W.S.4
-
54
-
-
28644433990
-
Expressions of inducible nitric oxide synthase and matrix metalloproteinase-9 and their effects on angiogenesis and progression of hepatocellular carcinoma
-
Sun, M. H.; Han, X. C.; Jia, M. K.; Jiang, W. D.; Wang, M.; Zhang, H.; Han, G,; Jiang, Y. Expressions of inducible nitric oxide synthase and matrix metalloproteinase-9 and their effects on angiogenesis and progression of hepatocellular carcinoma. World J. Gastroenterol. 2005, 11, 5931-5937.
-
(2005)
World J. Gastroenterol
, vol.11
, pp. 5931-5937
-
-
Sun, M.H.1
Han, X.C.2
Jia, M.K.3
Jiang, W.D.4
Wang, M.5
Zhang, H.6
Han, G.7
Jiang, Y.8
-
55
-
-
0034544619
-
Constitutive activation of nuclear factor kappaB in hepatocellular carcinoma
-
Tai, D. I.; Tsai, S. L.; Chang, Y. H.; Huang, S. N.; Chen, T. C.; Chang, K. S.; Liaw, Y. F. Constitutive activation of nuclear factor kappaB in hepatocellular carcinoma. Cancer 2000, 89, 2274-2281.
-
(2000)
Cancer
, vol.89
, pp. 2274-2281
-
-
Tai, D.I.1
Tsai, S.L.2
Chang, Y.H.3
Huang, S.N.4
Chen, T.C.5
Chang, K.S.6
Liaw, Y.F.7
-
56
-
-
33645457576
-
Constitutive activation of NF-kappaB in human hepatocellular carcinoma: Evidence of a cytoprotective role
-
Qiao, L.; Zhang, H.; Yu, J.; Francisco, R.; Dent, P.; Ebert, M. P.; Röcken, C.; Farrell, G. Constitutive activation of NF-kappaB in human hepatocellular carcinoma: evidence of a cytoprotective role. Hum. Gene Ther. 2006, 17, 280-290.
-
(2006)
Hum. Gene Ther
, vol.17
, pp. 280-290
-
-
Qiao, L.1
Zhang, H.2
Yu, J.3
Francisco, R.4
Dent, P.5
Ebert, M.P.6
Röcken, C.7
Farrell, G.8
-
57
-
-
37549004392
-
Nuclear factor-κB: From bench to bedside
-
Sethi, G.; Sung, B.; Aggarwal, B. B. Nuclear factor-κB: from bench to bedside. Exp. Biol. Med. 2008, 233, 21-31.
-
(2008)
Exp. Biol. Med
, vol.233
, pp. 21-31
-
-
Sethi, G.1
Sung, B.2
Aggarwal, B.B.3
-
58
-
-
70449404610
-
Nuclear factor-kappa B links carcicinogenesis and chemopreventive agents
-
Ralhan, R.; Pandey, M. K.; Aggarwal, B. B. Nuclear factor-kappa B links carcicinogenesis and chemopreventive agents. Front. Biosci. (Schol. Ed.) 2009, 1, 45-60.
-
(2009)
Front. Biosci. (Schol. Ed.)
, vol.1
, pp. 45-60
-
-
Ralhan, R.1
Pandey, M.K.2
Aggarwal, B.B.3
-
59
-
-
1142275252
-
Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma
-
Futakuchi, M.; Ogawa, K.; Tamano, S.; Takahashi, S.; Shirai, T. Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma. Cancer Sci. 2004, 95, 18-24.
-
(2004)
Cancer Sci
, vol.95
, pp. 18-24
-
-
Futakuchi, M.1
Ogawa, K.2
Tamano, S.3
Takahashi, S.4
Shirai, T.5
-
60
-
-
77952163228
-
The role of NF-kappaB in Hepatitis b virus X protein-mediated upregulation of VEGF and MMPs
-
Liu, L. P.; Liang, H. F.; Chen, X. P.; Zhang, W. G.; Yang, S. L.; Xu, T.; Ren, L. The role of NF-kappaB in Hepatitis b virus X protein-mediated upregulation of VEGF and MMPs. Cancer Invest. 2010, 28, 443-451.
-
(2010)
Cancer Invest
, vol.28
, pp. 443-451
-
-
Liu, L.P.1
Liang, H.F.2
Chen, X.P.3
Zhang, W.G.4
Yang, S.L.5
Xu, T.6
Ren, L.7
-
61
-
-
0141651577
-
Plateletderived endothelial cell growth factor (PD-ECGF) is up-regulated in human hepatocellular carcinoma (HCC) and the corresponding hepatitis liver
-
Morinaga, S.; Yamamoto, Y.; Noguchi, Y.; Imada, T.; Rino, Y.; Akaike, M.; Sugimasa, Y.; Takemiya, S.; Takanashi, Y. Plateletderived endothelial cell growth factor (PD-ECGF) is up-regulated in human hepatocellular carcinoma (HCC) and the corresponding hepatitis liver. Hepatogastroenterology 2003, 50, 1521-1526.
-
(2003)
Hepatogastroenterology
, vol.50
, pp. 1521-1526
-
-
Morinaga, S.1
Yamamoto, Y.2
Noguchi, Y.3
Imada, T.4
Rino, Y.5
Akaike, M.6
Sugimasa, Y.7
Takemiya, S.8
Takanashi, Y.9
-
62
-
-
21644487583
-
Prognostic value of thymidine phosphorylase activity in liver tissue adjacent to hepatocellular carcinoma
-
Ezaki, T.; Ikegami, T.; Maeda, T.; Yamada, T.; Ishida, T.; Hashizume, M.; Maehara, Y. Prognostic value of thymidine phosphorylase activity in liver tissue adjacent to hepatocellular carcinoma. Int. J. Clin. Oncol. 2005, 10, 171-176.
-
(2005)
Int. J. Clin. Oncol
, vol.10
, pp. 171-176
-
-
Ezaki, T.1
Ikegami, T.2
Maeda, T.3
Yamada, T.4
Ishida, T.5
Hashizume, M.6
Maehara, Y.7
-
63
-
-
0031019745
-
Isolation of putative progenitor endothelial cells for angiogenesis
-
Asahara, T.; Murohara, T.; Sullivan, A.; Silver, M.; van der Zee, R.; Li, T.; Witzenbichler, B.; Schatteman, G.; Isner, J. M. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997, 275, 964-967.
-
(1997)
Science
, vol.275
, pp. 964-967
-
-
Asahara, T.1
Murohara, T.2
Sullivan, A.3
Silver, M.4
van der Zee, R.5
Li, T.6
Witzenbichler, B.7
Schatteman, G.8
Isner, J.M.9
-
64
-
-
0034906312
-
The clinicopathological significance of heparanase and basic fibroblast growth factor expressions in hepatocellular carcinoma
-
El-Assal, O. N.; Yamanoi, A.; Ono, T.; Kohno, H.; Nagasue, N. The clinicopathological significance of heparanase and basic fibroblast growth factor expressions in hepatocellular carcinoma. Clin. Cancer Res. 2001, 7, 1299-1305.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 1299-1305
-
-
El-Assal, O.N.1
Yamanoi, A.2
Ono, T.3
Kohno, H.4
Nagasue, N.5
-
65
-
-
0027297822
-
Sinusoidal capillarization of human hepatocellular carcinoma: Possible promotion by fibroblast growth factor
-
Motoo, Y.; Sawabu, N.; Yamaguchi, Y.; Terada, T.; Nakanuma, Y. Sinusoidal capillarization of human hepatocellular carcinoma: possible promotion by fibroblast growth factor. Oncology 1993, 50, 270-274.
-
(1993)
Oncology
, vol.50
, pp. 270-274
-
-
Motoo, Y.1
Sawabu, N.2
Yamaguchi, Y.3
Terada, T.4
Nakanuma, Y.5
-
66
-
-
85047696179
-
Hepatocyte growth factor promotes hepatocarcinogenesis through c-Met autocrine activation and enhanced angiogenesis in transgenic mice treated with diethylnitrosamine
-
Horiguchi, N.; Takayama, H.; Toyoda, M.; Otsuka, T.; Fukusato, T.; Merlino, G.; Takagi, H; Mori, M. Hepatocyte growth factor promotes hepatocarcinogenesis through c-Met autocrine activation and enhanced angiogenesis in transgenic mice treated with diethylnitrosamine. Oncogene 2002, 21, 1791-1799.
-
(2002)
Oncogene
, vol.21
, pp. 1791-1799
-
-
Horiguchi, N.1
Takayama, H.2
Toyoda, M.3
Otsuka, T.4
Fukusato, T.5
Merlino, G.6
Takagi, H.7
Mori, M.8
-
67
-
-
4043074287
-
TGFbeta1-promoted epithelial-to-mesenchymal transformation and cell adhesion contribute to TGF-beta1-enhanced cell migration in SMMC-7721 cells
-
Xu, Z.; Shen, M. X.; Ma, D. Z.; Wang, L. Y.; Zha, X. L. TGFbeta1-promoted epithelial-to-mesenchymal transformation and cell adhesion contribute to TGF-beta1-enhanced cell migration in SMMC-7721 cells. Cell Res. 2003, 13, 343-350.
-
(2003)
Cell Res
, vol.13
, pp. 343-350
-
-
Xu, Z.1
Shen, M.X.2
Ma, D.Z.3
Wang, L.Y.4
Zha, X.L.5
-
68
-
-
0028952342
-
Positive correlation of plasma transforming growth factor-beta 1 levels with tumor vascularity in hepatocellular carcinoma
-
Ito, N.; Kawata, S.; Tamura, S.; Shirai, Y.; Kiso, S.; Tsushima, H.; Matsuzawa, Y. Positive correlation of plasma transforming growth factor-beta 1 levels with tumor vascularity in hepatocellular carcinoma. Cancer Lett. 1995, 89, 45-48.
-
(1995)
Cancer Lett
, vol.89
, pp. 45-48
-
-
Ito, N.1
Kawata, S.2
Tamura, S.3
Shirai, Y.4
Kiso, S.5
Tsushima, H.6
Matsuzawa, Y.7
-
69
-
-
54249139202
-
Transforming growth factor-beta1 and CD105 promote the migration of hepatocellular carcinoma-derived endothelium
-
Benetti, A.; Berenzi, A.; Gambarotti, M.; Garrafa, E.; Gelati, M.; Dessy, E.; Portolani, N.; Piardi, T.; Giulini, S. M.; Caruso, A.; Invernici, G.; Parati, E.A.; Nicosia, R.; Alessandri, G. Transforming growth factor-beta1 and CD105 promote the migration of hepatocellular carcinoma-derived endothelium. Cancer Res. 2008, 68, 8626-8634.
-
(2008)
Cancer Res
, vol.68
, pp. 8626-8634
-
-
Benetti, A.1
Berenzi, A.2
Gambarotti, M.3
Garrafa, E.4
Gelati, M.5
Dessy, E.6
Portolani, N.7
Piardi, T.8
Giulini, S.M.9
Caruso, A.10
Invernici, G.11
Parati, E.A.12
Nicosia, R.13
Alessandri, G.14
-
70
-
-
0037902227
-
Tumoral angiogenesis and tissue factor expression during hepatocellular carcinoma progression in a transgenic mouse model
-
Dupuy, E.; Hainaud, P.; Villemain, A.; Bodevin-Phèdre, E.; Brouland, J. P.; Briand, P.; Tobelem, G. Tumoral angiogenesis and tissue factor expression during hepatocellular carcinoma progression in a transgenic mouse model. J. Hepatol. 2003, 38, 793-802.
-
(2003)
J. Hepatol
, vol.38
, pp. 793-802
-
-
Dupuy, E.1
Hainaud, P.2
Villemain, A.3
Bodevin-Phèdre, E.4
Brouland, J.P.5
Briand, P.6
Tobelem, G.7
-
71
-
-
0242525613
-
Tissue factor expression correlates with tumor angiogenesis and invasiveness in human hepatocellular carcinoma
-
Poon, R. T.; Lau, C. P.; Ho, J. W.; Yu, W. C.; Fan, S. T.; Wong, J. Tissue factor expression correlates with tumor angiogenesis and invasiveness in human hepatocellular carcinoma. Clin. Cancer Res. 2003, 9, 5339-5345.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 5339-5345
-
-
Poon, R.T.1
Lau, C.P.2
Ho, J.W.3
Yu, W.C.4
Fan, S.T.5
Wong, J.6
-
72
-
-
11144354466
-
Overexpression of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma
-
Torimura, T.; Ueno, T.; Kin, M.; Harada, R.; Taniguchi, E.; Nakamura, T.; Sakata, R.; Hashimoto, O.; Sakamoto, M.; Kumashiro, R.; Sata, M.; Nakashima, O.; Yano, H.; Kojiro, M. Overexpression of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma. J. Hepatol. 2004, 40, 799-807.
-
(2004)
J. Hepatol
, vol.40
, pp. 799-807
-
-
Torimura, T.1
Ueno, T.2
Kin, M.3
Harada, R.4
Taniguchi, E.5
Nakamura, T.6
Sakata, R.7
Hashimoto, O.8
Sakamoto, M.9
Kumashiro, R.10
Sata, M.11
Nakashima, O.12
Yano, H.13
Kojiro, M.14
-
73
-
-
0038374813
-
Angiopoietins and Tie-2 expression in angiogenesis and proliferation of human hepatocellular carcinoma
-
Mitsuhashi, N.; Shimizu, H.; Ohtsuka, M.; Wakabayashi, Y.; Ito, H.; Kimura F.; Yoshidome, H.; Kato, A.; Nukui, Y.; Miyazaki, M. Angiopoietins and Tie-2 expression in angiogenesis and proliferation of human hepatocellular carcinoma. Hepatology 2003, 37, 1105-1113.
-
(2003)
Hepatology
, vol.37
, pp. 1105-1113
-
-
Mitsuhashi, N.1
Shimizu, H.2
Ohtsuka, M.3
Wakabayashi, Y.4
Ito, H.5
Kimura, F.6
Yoshidome, H.7
Kato, A.8
Nukui, Y.9
Miyazaki, M.10
-
74
-
-
33645740560
-
Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma: Importance of angiopoietin-2 and hypoxia-induced factor-1 alpha
-
Wada, H.; Nagano, H.; Yamamoto, H.; Yang, Y.; Kondo, M.; Ota, H.; Nakamura, M.; Yoshioka, S.; Kato, H.; Damdinsuren, B.; Tang, D.; Marubashi, S.; Miyamoto, A.; Takeda, Y.; Umeshita, K.; Nakamori, S.; Sakon, M.; Dono, K.; Wakasa, K.; Monden, M. Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma: importance of angiopoietin-2 and hypoxia-induced factor-1 alpha. Liver Int. 2006, 26, 414-423.
-
(2006)
Liver Int
, vol.26
, pp. 414-423
-
-
Wada, H.1
Nagano, H.2
Yamamoto, H.3
Yang, Y.4
Kondo, M.5
Ota, H.6
Nakamura, M.7
Yoshioka, S.8
Kato, H.9
Damdinsuren, B.10
Tang, D.11
Marubashi, S.12
Miyamoto, A.13
Takeda, Y.14
Umeshita, K.15
Nakamori, S.16
Sakon, M.17
Dono, K.18
Wakasa, K.19
Monden, M.20
more..
-
75
-
-
0023181351
-
Tissue distribution and developmental expression of the messenger RNA encoding angiogenin
-
Weiner, H. L.; Weiner, L. H.; Swain, J. L. Tissue distribution and developmental expression of the messenger RNA encoding angiogenin. Science 1987, 237, 280-282.
-
(1987)
Science
, vol.237
, pp. 280-282
-
-
Weiner, H.L.1
Weiner, L.H.2
Swain, J.L.3
-
76
-
-
0029994790
-
Increased serum laminin and angiogenin concentrations in patients with peripheral arterial occlusive disease
-
Burgmann, H.; Hollenstein, U.; Maca, T.; Zedwitz-Liebenstein, K.; Thalhammer, F.; Koppensteiner, R.; Ehringer, H.; Graninger, W. Increased serum laminin and angiogenin concentrations in patients with peripheral arterial occlusive disease. J. Clin. Pathol. 1996, 49, 508-510.
-
(1996)
J. Clin. Pathol
, vol.49
, pp. 508-510
-
-
Burgmann, H.1
Hollenstein, U.2
Maca, T.3
Zedwitz-Liebenstein, K.4
Thalhammer, F.5
Koppensteiner, R.6
Ehringer, H.7
Graninger, W.8
-
77
-
-
10744220077
-
Increased expression of angiogenin in hepatocellular carcinoma in correlation with tumor vascularity
-
Hisai, H.; Kato, J.; Kobune, M.; Murakami, T.; Miyanishi, K.; Takahashi, M.; Yoshizaki, N.; Takimoto, R.; Terui, T.; Niitsu, Y. Increased expression of angiogenin in hepatocellular carcinoma in correlation with tumor vascularity. Clin. Cancer Res. 2003, 9, 4852-4859.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 4852-4859
-
-
Hisai, H.1
Kato, J.2
Kobune, M.3
Murakami, T.4
Miyanishi, K.5
Takahashi, M.6
Yoshizaki, N.7
Takimoto, R.8
Terui, T.9
Niitsu, Y.10
-
78
-
-
0036362236
-
Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth
-
Lawler, J. Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth. J. Cell Mol. Med. 2002, 6, 1-12.
-
(2002)
J. Cell Mol. Med
, vol.6
, pp. 1-12
-
-
Lawler, J.1
-
79
-
-
17344365783
-
Enhanced expression of thrombospondin-1 and hypovascularity in human cholangiocarcinoma
-
Kawahara, N.; Ono, M.; Taguchi, K.; Okamoto, M.; Shimada, M.; Takenaka, K.; Hayashi, K.; Mosher, D. F.; Sugimachi, K.; Tsuneyoshi, M.; Kuwano, M. Enhanced expression of thrombospondin-1 and hypovascularity in human cholangiocarcinoma. Hepatology 1998, 28, 1512-1517.
-
(1998)
Hepatology
, vol.28
, pp. 1512-1517
-
-
Kawahara, N.1
Ono, M.2
Taguchi, K.3
Okamoto, M.4
Shimada, M.5
Takenaka, K.6
Hayashi, K.7
Mosher, D.F.8
Sugimachi, K.9
Tsuneyoshi, M.10
Kuwano, M.11
-
80
-
-
3042670492
-
Clinical significance of thrombospondin 1 expression in hepatocellular carcinoma
-
Poon, R. T.; Chung, K. K.; Cheung, S. T.; Lau, C. P.; Tong, S. W.; Leung, K. L.; Yu, W. C.; Tuszynski, G. P.; Fan, S. T. Clinical significance of thrombospondin 1 expression in hepatocellular carcinoma. Clin. Cancer Res. 2004, 10, 4150-4157.
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 4150-4157
-
-
Poon, R.T.1
Chung, K.K.2
Cheung, S.T.3
Lau, C.P.4
Tong, S.W.5
Leung, K.L.6
Yu, W.C.7
Tuszynski, G.P.8
Fan, S.T.9
-
81
-
-
0033984320
-
Implications of human macrophage metalloelastase and vascular endothelial growth factor gene expression in angiogenesis of hepatocellular carcinoma
-
Gorrin-Rivas, M. J.; Arii, S.; Mori, A.; Takeda, Y.; Mizumoto, M.; Furutani, M.; Imamura, M. Implications of human macrophage metalloelastase and vascular endothelial growth factor gene expression in angiogenesis of hepatocellular carcinoma. Ann. Surg. 2000, 231, 67-73.
-
(2000)
Ann. Surg
, vol.231
, pp. 67-73
-
-
Gorrin-Rivas, M.J.1
Arii, S.2
Mori, A.3
Takeda, Y.4
Mizumoto, M.5
Furutani, M.6
Imamura, M.7
-
82
-
-
9144226806
-
Human apolipoprotein(a) kringle V inhibits angiogenesis in vitro and in vivo by interfering with the activation of focal adhesion kinases
-
Kim, J. S.; Yu, H. K.; Ahn, J. H.; Lee, H. J.; Hong, S. W.; Jung, K. H.; Chang, S. I.; Hong, Y. K.; Joe, Y. A.; Byun, S. M.; Lee, S. K.; Chung, S. I.; Yoon, Y. Human apolipoprotein(a) kringle V inhibits angiogenesis in vitro and in vivo by interfering with the activation of focal adhesion kinases. Biochem. Biophys. Res. Commun. 2004, 313, 534-540.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.313
, pp. 534-540
-
-
Kim, J.S.1
Yu, H.K.2
Ahn, J.H.3
Lee, H.J.4
Hong, S.W.5
Jung, K.H.6
Chang, S.I.7
Hong, Y.K.8
Joe, Y.A.9
Byun, S.M.10
Lee, S.K.11
Chung, S.I.12
Yoon, Y.13
-
83
-
-
0035132924
-
Tumor progression is associated with a significant decrease in the expression of the endostatin precursor collagen XVIII in human hepatocellular carcinomas
-
Musso, O.; Rehn, M.; Théret, N.; Turlin, B.; Bioulac-Sage, P.; Lotrian, D.; Campion, J. P.; Pihlajaniemi, T.; Clément, B. Tumor progression is associated with a significant decrease in the expression of the endostatin precursor collagen XVIII in human hepatocellular carcinomas. Cancer Res. 2001, 61, 45-49.
-
(2001)
Cancer Res
, vol.61
, pp. 45-49
-
-
Musso, O.1
Rehn, M.2
Théret, N.3
Turlin, B.4
Bioulac-Sage, P.5
Lotrian, D.6
Campion, J.P.7
Pihlajaniemi, T.8
Clément, B.9
-
84
-
-
0037110699
-
Serum endostatin predicts tumor vascularity in hepatocellular carcinoma
-
Dhar, D. K.; Ono, T.; Yamanoi, A.; Soda, Y.; Yamaguchi, E.; Rahman, M. A.; Kohno, H.; Nagasue, N. Serum endostatin predicts tumor vascularity in hepatocellular carcinoma. Cancer 2002, 95, 2188-2195.
-
(2002)
Cancer
, vol.95
, pp. 2188-2195
-
-
Dhar, D.K.1
Ono, T.2
Yamanoi, A.3
Soda, Y.4
Yamaguchi, E.5
Rahman, M.A.6
Kohno, H.7
Nagasue, N.8
-
85
-
-
0034907881
-
The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: Possible role of the vascular endothelial growth factor
-
Yoshiji, H.; Kuriyama, S.; Kawata. M.; Yoshii, J.; Ikenaka, Y.; Noguchi, R.; Nakatani, T.; Tsujinoue, H.; Fukui, H. The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: possible role of the vascular endothelial growth factor. Clin. Cancer Res. 2001, 7, 1073-1078.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 1073-1078
-
-
Yoshiji, H.1
Kuriyama, S.2
Kawata, M.3
Yoshii, J.4
Ikenaka, Y.5
Noguchi, R.6
Nakatani, T.7
Tsujinoue, H.8
Fukui, H.9
-
86
-
-
0036617271
-
Suppression of the reninangiotensin system attenuates vascular endothelial growth factormediated tumor development and angiogenesis in murine hepatocellular carcinoma cells
-
Yoshiji, H.; Yoshii, J.; Ikenaka, Y.; Noguchi, R.; Yanase, K.; Tsujinoue, H.; Imazu, H.; Fukui, H. Suppression of the reninangiotensin system attenuates vascular endothelial growth factormediated tumor development and angiogenesis in murine hepatocellular carcinoma cells. Int. J. Oncol. 2002, 20, 1227-1231.
-
(2002)
Int. J. Oncol
, vol.20
, pp. 1227-1231
-
-
Yoshiji, H.1
Yoshii, J.2
Ikenaka, Y.3
Noguchi, R.4
Yanase, K.5
Tsujinoue, H.6
Imazu, H.7
Fukui, H.8
-
87
-
-
0023159806
-
Interferons and their actions
-
Pestka, S.; Langer, J. A.; Zoon, K.C.; Samuel, C. E. Interferons and their actions. Annu. Rev. Biochem. 1987, 56, 727-777.
-
(1987)
Annu. Rev. Biochem
, vol.56
, pp. 727-777
-
-
Pestka, S.1
Langer, J.A.2
Zoon, K.C.3
Samuel, C.E.4
-
88
-
-
0347995046
-
Combination of interferon-beta and the angiotensin-converting enzyme inhibitor, perindopril, attenuates murine hepatocellular carcinoma development and angiogenesis
-
Noguchi, R.; Yoshiji, H.; Kuriyama, S.; Yoshii, J.; Ikenaka, Y.; Yanase, K.; Namisaki, T.; Kitade, M.; Yamazaki, M.; Mitoro, A.; Tsujinoue, H.; Imazu, H.; Masaki, T.; Fukui, H. Combination of interferon-beta and the angiotensin-converting enzyme inhibitor, perindopril, attenuates murine hepatocellular carcinoma development and angiogenesis. Clin. Cancer Res. 2003, 9, 6038-6045.
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 6038-6045
-
-
Noguchi, R.1
Yoshiji, H.2
Kuriyama, S.3
Yoshii, J.4
Ikenaka, Y.5
Yanase, K.6
Namisaki, T.7
Kitade, M.8
Yamazaki, M.9
Mitoro, A.10
Tsujinoue, H.11
Imazu, H.12
Masaki, T.13
Fukui, H.14
-
89
-
-
15044356179
-
Combination of interferon and angiotensin-converting enzyme inhibitor, perindopril, suppresses liver carcinogenesis and angiogenesis in mice
-
Yoshiji, H.; Noguchi, R.; Kuriyama, S.; Yoshii, J.; Ikenaka, Y. Combination of interferon and angiotensin-converting enzyme inhibitor, perindopril, suppresses liver carcinogenesis and angiogenesis in mice. Oncol. Rep. 2005, 13, 491-495.
-
(2005)
Oncol. Rep
, vol.13
, pp. 491-495
-
-
Yoshiji, H.1
Noguchi, R.2
Kuriyama, S.3
Yoshii, J.4
Ikenaka, Y.5
-
90
-
-
0042252159
-
Vitamin K cuts hepatocellular carcinoma mortality
-
Jancin, B. Vitamin K cuts hepatocellular carcinoma mortality. Fam. Pract. News 2002, 32.
-
(2002)
Fam. Pract. News
, pp. 32
-
-
Jancin, B.1
-
91
-
-
20144389070
-
2 and the angiotensinconverting enzyme inhibitor, perindopril, attenuates the liver enzyme-altered preneoplastic lesions in rats via angiogenesis suppression
-
2 and the angiotensinconverting enzyme inhibitor, perindopril, attenuates the liver enzyme-altered preneoplastic lesions in rats via angiogenesis suppression. J. Hepatol. 2005, 42, 687-693.
-
(2005)
J. Hepatol
, vol.42
, pp. 687-693
-
-
Yoshiji, H.1
Kuriyama, S.2
Noguchi, R.3
Yoshii, J.4
Ikenaka, Y.5
Yanase, K.6
Namisaki, T.7
Kitade, M.8
Yamazaki, M.9
Masaki, T.10
Fukui, H.11
-
92
-
-
33644877833
-
2 and angiotensin-converting enzyme inhibitor via antiangiogenic activities
-
2 and angiotensin-converting enzyme inhibitor via antiangiogenic activities. Oncol. Rep. 2006, 15, 155-159.
-
(2006)
Oncol. Rep
, vol.15
, pp. 155-159
-
-
Yoshiji, H.1
Kuriyama, S.2
Noguchi, R.3
Yoshii, J.4
Ikenaka, Y.5
Yanase, K.6
Namisaki, T.7
Kitade, M.8
Yamazaki, M.9
Akahane, T.10
Asada, K.11
Tsujimoto, T.12
Uemura, M.13
Fukui, H.14
-
93
-
-
33947720545
-
Synergistic inhibition of hepatocellular carcinoma growth and hepatocarcinogenesis by combination of 5-fluorouracil and angiotensin-converting enzyme inhibitor via anti-angiogenic activities
-
Yanase, K.; Yoshiji, H.; Ikenaka, Y.; Noguchi, R.; Kitade, M.; Kaji, K.; Yoshii, J.; Namisaki, T.; Yamazaki, M.; Asada, K.; Tsujimoto, T.; Akahane, T.; Uemura, M.; Fukui, H. Synergistic inhibition of hepatocellular carcinoma growth and hepatocarcinogenesis by combination of 5-fluorouracil and angiotensin-converting enzyme inhibitor via anti-angiogenic activities. Oncol. Rep. 2007, 17, 441-446.
-
(2007)
Oncol. Rep
, vol.17
, pp. 441-446
-
-
Yanase, K.1
Yoshiji, H.2
Ikenaka, Y.3
Noguchi, R.4
Kitade, M.5
Kaji, K.6
Yoshii, J.7
Namisaki, T.8
Yamazaki, M.9
Asada, K.10
Tsujimoto, T.11
Akahane, T.12
Uemura, M.13
Fukui, H.14
-
94
-
-
0037372605
-
Antiangiogenic gene therapy for hepatocellular carcinoma using angiostatin gene
-
Ishikawa, H.; Nakao, K.; Matsumoto, K.; Ichikawa, T.; Hamasaki, K.; Nakata, K.; Eguchi, K. Antiangiogenic gene therapy for hepatocellular carcinoma using angiostatin gene. Hepatology 2003, 37, 696-704.
-
(2003)
Hepatology
, vol.37
, pp. 696-704
-
-
Ishikawa, H.1
Nakao, K.2
Matsumoto, K.3
Ichikawa, T.4
Hamasaki, K.5
Nakata, K.6
Eguchi, K.7
-
95
-
-
21044453333
-
Inhibitory effect of adeno-associated virus-mediated gene transfer of human endostatin on hepatocellular carcinoma
-
Liu, H.; Peng, C. H.; Liu, Y. B.; Wu, Y. L.; Zhao, Z. M.; Wang, Y.; Han, B. S. Inhibitory effect of adeno-associated virus-mediated gene transfer of human endostatin on hepatocellular carcinoma. World J. Gastroenterol. 2005, 11, 3331-3334.
-
(2005)
World J. Gastroenterol
, vol.11
, pp. 3331-3334
-
-
Liu, H.1
Peng, C.H.2
Liu, Y.B.3
Wu, Y.L.4
Zhao, Z.M.5
Wang, Y.6
Han, B.S.7
-
96
-
-
0025204095
-
Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth
-
Ingber, D.; Fujita, T.; Kishimoto, S.; Sudo, K.; Kanamaru, T.; Brem, H.; Folkman, J. Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature 1990, 348, 555-557.
-
(1990)
Nature
, vol.348
, pp. 555-557
-
-
Ingber, D.1
Fujita, T.2
Kishimoto, S.3
Sudo, K.4
Kanamaru, T.5
Brem, H.6
Folkman, J.7
-
97
-
-
0029098805
-
Intra-arterial administration of the angiogenesis inhibitor TNP-470 blocks liver metastasis in a rabbit model
-
Tanaka, H.; Taniguchi, H.; Mugitani, T.; Koishi, Y.; Masuyama, M.; Higashida, T.; Koyama, H.; Suganuma, Y.; Miyata, K.; Takeuchi, K.; Takahashi, T. Intra-arterial administration of the angiogenesis inhibitor TNP-470 blocks liver metastasis in a rabbit model. Br. J. Cancer 1995, 72, 650-653.
-
(1995)
Br. J. Cancer
, vol.72
, pp. 650-653
-
-
Tanaka, H.1
Taniguchi, H.2
Mugitani, T.3
Koishi, Y.4
Masuyama, M.5
Higashida, T.6
Koyama, H.7
Suganuma, Y.8
Miyata, K.9
Takeuchi, K.10
Takahashi, T.11
-
98
-
-
0034131857
-
Angiogenesis inhibitor TNP-470 suppresses the progression of experimentally-induced hepatocellular carcinoma in rats
-
Kin, M.; Torimura, T.; Ueno, T.; Nakamura, T.; Ogata, R.; Sakamoto, M.; Tamaki, S.; Sata, M. Angiogenesis inhibitor TNP-470 suppresses the progression of experimentally-induced hepatocellular carcinoma in rats. Int. J. Oncol. 2000, 16, 375-382.
-
(2000)
Int. J. Oncol
, vol.16
, pp. 375-382
-
-
Kin, M.1
Torimura, T.2
Ueno, T.3
Nakamura, T.4
Ogata, R.5
Sakamoto, M.6
Tamaki, S.7
Sata, M.8
-
99
-
-
33845687007
-
Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism
-
Mauriz, J. L.; Gonzalez, P.; Duran, M. C.; Molpeceres, V.; Culebras, J. M.; Gonzalez-Gallego, J. Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism. Transl. Res. 2007, 149, 46-53.
-
(2007)
Transl. Res
, vol.149
, pp. 46-53
-
-
Mauriz, J.L.1
Gonzalez, P.2
Duran, M.C.3
Molpeceres, V.4
Culebras, J.M.5
Gonzalez-Gallego, J.6
-
100
-
-
0027276747
-
Angiogenesis inhibitors of microbial origin
-
Terano, H.; Shibata, T.; Otsuka, T. Angiogenesis inhibitors of microbial origin. Drug Future 1993, 18, 239.
-
(1993)
Drug Future
, vol.18
, pp. 239
-
-
Terano, H.1
Shibata, T.2
Otsuka, T.3
-
101
-
-
71649103286
-
Anti-angiogenic therapy on hepatocellular carcinoma development and progression
-
Ishii, Y.; Sakamoto, T.; Ito, R.; Yanaga, K. Anti-angiogenic therapy on hepatocellular carcinoma development and progression. J. Surg. Res. 2010, 158, 69-76.
-
(2010)
J. Surg. Res
, vol.158
, pp. 69-76
-
-
Ishii, Y.1
Sakamoto, T.2
Ito, R.3
Yanaga, K.4
-
102
-
-
0037383444
-
Ribozymes: Recent advances in the development of RNA tools
-
Puerta-Fernández, E.; Romero-López, C.; Barroso-delJesus, A.; Berzal-Herranz, A. Ribozymes: recent advances in the development of RNA tools. FEMS Microbiol. Rev. 2003, 27, 75-97.
-
(2003)
FEMS Microbiol. Rev
, vol.27
, pp. 75-97
-
-
Puerta-Fernández, E.1
Romero-López, C.2
Barroso-delJesus, A.3
Berzal-Herranz, A.4
-
103
-
-
37649022050
-
Antitumor and antiangiogenic activities of anti-vascular endothelial growth factor hairpin ribozyme in human hepatocellular carcinoma cell cultures and xenografts
-
Li, L. H.; Guo, Z. J.; Yan, L. L.; Yang, J. C.; Xie, Y. F.; Sheng, W. H.; Huang, Z. H.; Wang XH. Antitumor and antiangiogenic activities of anti-vascular endothelial growth factor hairpin ribozyme in human hepatocellular carcinoma cell cultures and xenografts. World J. Gastroenterol. 2007, 13, 6425-6432.
-
(2007)
World J. Gastroenterol
, vol.13
, pp. 6425-6432
-
-
Li, L.H.1
Guo, Z.J.2
Yan, L.L.3
Yang, J.C.4
Xie, Y.F.5
Sheng, W.H.6
Huang, Z.H.7
Wang, X.H.8
-
104
-
-
84862751803
-
A novel monoclonal antibody to fibroblast growth factor 2 effectively inhibits growth of hepatocellular carcinoma xenografts
-
Wang, L.; Park, H.; Chhim, S.; Ding, Y.; Jiang, W.; Queen, C.; Kim, K. J. A novel monoclonal antibody to fibroblast growth factor 2 effectively inhibits growth of hepatocellular carcinoma xenografts. Mol. Cancer Ther. 2012, 11, 864-872.
-
(2012)
Mol. Cancer Ther
, vol.11
, pp. 864-872
-
-
Wang, L.1
Park, H.2
Chhim, S.3
Ding, Y.4
Jiang, W.5
Queen, C.6
Kim, K.J.7
-
105
-
-
77950263970
-
Suppression of tumor growth and metastasis by simultaneously blocking vascular endothelial growth factor (VEGF)-A and VEGF-C with a receptorimmunoglobulin fusion protein
-
Zhang, D.; Li, B.; Shi, J.; Zhao, L.; Zhang, X.; Wang, C.; Hou, S.; Qian, W.; Kou, G.; Wang, H.; Guo, Y. Suppression of tumor growth and metastasis by simultaneously blocking vascular endothelial growth factor (VEGF)-A and VEGF-C with a receptorimmunoglobulin fusion protein. Cancer Res. 2010, 70, 2495-2503.
-
(2010)
Cancer Res
, vol.70
, pp. 2495-2503
-
-
Zhang, D.1
Li, B.2
Shi, J.3
Zhao, L.4
Zhang, X.5
Wang, C.6
Hou, S.7
Qian, W.8
Kou, G.9
Wang, H.10
Guo, Y.11
-
106
-
-
0037704549
-
Mechanism of interferon alpha on inhibition of metastasis and angiogenesis of hepatocellular carcinoma after curative resection in nude mice
-
Wang, L.; Wu, W. Z.; Sun, H. C.; Wu, X. F.; Qin, L. X.; Liu, Y. K.; Liu, K. D.; Tang, Z. Y. Mechanism of interferon alpha on inhibition of metastasis and angiogenesis of hepatocellular carcinoma after curative resection in nude mice. J. Gastrointest. Surg. 2003, 7, 587-594.
-
(2003)
J. Gastrointest. Surg
, vol.7
, pp. 587-594
-
-
Wang, L.1
Wu, W.Z.2
Sun, H.C.3
Wu, X.F.4
Qin, L.X.5
Liu, Y.K.6
Liu, K.D.7
Tang, Z.Y.8
-
107
-
-
34250848988
-
Growth inhibitory effects of IFN-β on human liver cancer cells in vitro and in vivo
-
Ogasawara, S.; Yano, H.; Momosaki, S.; Akiba, J.; Nishida, N.; Kojiro, S.; Moriya, F.; Ishizaki, H.; Kuratomi, K.; Kojiro, M. Growth inhibitory effects of IFN-β on human liver cancer cells in vitro and in vivo. J. Interferon Cytokine Res. 2007, 27, 507-516.
-
(2007)
J. Interferon Cytokine Res
, vol.27
, pp. 507-516
-
-
Ogasawara, S.1
Yano, H.2
Momosaki, S.3
Akiba, J.4
Nishida, N.5
Kojiro, S.6
Moriya, F.7
Ishizaki, H.8
Kuratomi, K.9
Kojiro, M.10
-
108
-
-
9144260053
-
IL-12 gene therapy is an effective therapeutic strategy for hepatocellular carcinoma in immunosuppressed mice
-
Harada, N.; Shimada, M.; Okano, S.; Suehiro, T.; Soejima, Y.; Tomita, Y.; Maehara, Y. IL-12 gene therapy is an effective therapeutic strategy for hepatocellular carcinoma in immunosuppressed mice. J. Immunol. 2004, 173, 6635-6644.
-
(2004)
J. Immunol
, vol.173
, pp. 6635-6644
-
-
Harada, N.1
Shimada, M.2
Okano, S.3
Suehiro, T.4
Soejima, Y.5
Tomita, Y.6
Maehara, Y.7
-
109
-
-
77952575808
-
Differential antitumor effect of interleukin-12 family cytokines on orthotopic hepatocellular carcinoma
-
Lo, C. H.; Chang, C. M.; Tang, S. W.; Pan, W. Y.; Fang, C. C.; Chen, Y.; Wu, P. Y.; Chen, K. Y.; Ma, H. I.; Xiao, X.; Tao, M. H. Differential antitumor effect of interleukin-12 family cytokines on orthotopic hepatocellular carcinoma. J. Gene Med. 2010, 12, 423-434.
-
(2010)
J. Gene Med
, vol.12
, pp. 423-434
-
-
Lo, C.H.1
Chang, C.M.2
Tang, S.W.3
Pan, W.Y.4
Fang, C.C.5
Chen, Y.6
Wu, P.Y.7
Chen, K.Y.8
Ma, H.I.9
Xiao, X.10
Tao, M.H.11
-
110
-
-
77953195599
-
Interleukin-17F suppresses hepatocarcinoma cell growth via inhibition of tumor angiogenesis
-
Xie, Y.; Sheng, W.; Xiang, J.; Ye, Z.; Yang, J. Interleukin-17F suppresses hepatocarcinoma cell growth via inhibition of tumor angiogenesis. Cancer Invest. 2010, 28, 598-607.
-
(2010)
Cancer Invest
, vol.28
, pp. 598-607
-
-
Xie, Y.1
Sheng, W.2
Xiang, J.3
Ye, Z.4
Yang, J.5
-
111
-
-
11144354935
-
MDA-7/IL-24 is a unique cytokine-tumor suppressor in the IL-10 family
-
Chada, S.; Sutton, R. B.; Ekmekcioglu, S.; Ellerhorst, J.; Mumm, J. B.; Leitner, W. W.; Yang, H. Y.; Sahin, A. A.; Hunt, K. K.; Fuson, K. L.; Poìndexter, N.; Roth, J. A.; Ramesh, R.; Grimm, E. A.; Mhashilkar, A. M. MDA-7/IL-24 is a unique cytokine-tumor suppressor in the IL-10 family. Int. Immunopharmacol. 2004, 4, 649-667.
-
(2004)
Int. Immunopharmacol
, vol.4
, pp. 649-667
-
-
Chada, S.1
Sutton, R.B.2
Ekmekcioglu, S.3
Ellerhorst, J.4
Mumm, J.B.5
Leitner, W.W.6
Yang, H.Y.7
Sahin, A.A.8
Hunt, K.K.9
Fuson, K.L.10
Poìndexter, N.11
Roth, J.A.12
Ramesh, R.13
Grimm, E.A.14
Mhashilkar, A.M.15
-
112
-
-
34247881993
-
Adenovirusmediated Il-24 expression suppresses hepatocellular carcinoma growth via induction of cell apoptosis and cycling arrest and reduction of angiogenesis
-
Wang, X.; Ye, Z.; Zhong, J.; Xiang, J.; Yang J. Adenovirusmediated Il-24 expression suppresses hepatocellular carcinoma growth via induction of cell apoptosis and cycling arrest and reduction of angiogenesis. Cancer Biother. Radiopharm. 2007, 22, 56-63.
-
(2007)
Cancer Biother. Radiopharm
, vol.22
, pp. 56-63
-
-
Wang, X.1
Ye, Z.2
Zhong, J.3
Xiang, J.4
Yang, J.5
-
113
-
-
0028372227
-
Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite
-
Fujita, T.; Inoue, K.; Yamamoto, S.; Ikumoto, T.; Sasaki, S.; Toyama, R.; Chiba, K.; Hoshino, Y.; Okumoto, T. Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite. J. Antibiot. (Tokyo) 1994, 47, 208-215.
-
(1994)
J. Antibiot. (Tokyo)
, vol.47
, pp. 208-215
-
-
Fujita, T.1
Inoue, K.2
Yamamoto, S.3
Ikumoto, T.4
Sasaki, S.5
Toyama, R.6
Chiba, K.7
Hoshino, Y.8
Okumoto, T.9
-
114
-
-
0344443651
-
Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability
-
Sanchez, T.; Estrada-Hernandez, T.; Paik, J. H.; Wu, M. T.; Venkataraman, K.; Brinkmann, V.; Claffey, K.; Hla, T. Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability. J. Biol. Chem. 2003, 278, 47281-47290.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 47281-47290
-
-
Sanchez, T.1
Estrada-Hernandez, T.2
Paik, J.H.3
Wu, M.T.4
Venkataraman, K.5
Brinkmann, V.6
Claffey, K.7
Hla, T.8
-
115
-
-
33644697587
-
Effects of a novel immunomodulating agent, FTY720, on tumor growth and angiogenesis in hepatocellular carcinoma
-
Ho, J. W.; Man, K.; Sun, C. K.; Lee, T. K.; Poon, R. T.; Fan, S. T. Effects of a novel immunomodulating agent, FTY720, on tumor growth and angiogenesis in hepatocellular carcinoma. Mol. Cancer Ther. 2005, 4, 1430-1438.
-
(2005)
Mol. Cancer Ther
, vol.4
, pp. 1430-1438
-
-
Ho, J.W.1
Man, K.2
Sun, C.K.3
Lee, T.K.4
Poon, R.T.5
Fan, S.T.6
-
116
-
-
63549114458
-
Sirolimus inhibits the growth and metastatic progression of hepatocellular carcinoma
-
Wang, Z.; Zhou, J.; Fan, J.; Tan, C. J.; Qiu, S. J.; Yu, Y.; Huang, X. W.; Tang, Z. Y. Sirolimus inhibits the growth and metastatic progression of hepatocellular carcinoma. J. Cancer Res. Clin. Oncol. 2009, 135, 715-722.
-
(2009)
J. Cancer Res. Clin. Oncol
, vol.135
, pp. 715-722
-
-
Wang, Z.1
Zhou, J.2
Fan, J.3
Tan, C.J.4
Qiu, S.J.5
Yu, Y.6
Huang, X.W.7
Tang, Z.Y.8
-
117
-
-
73449100129
-
Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression
-
Quiles-Perez, R.; Muñoz-Gámez, J. A.; Ruiz-Extremera, A.; O'Valle, F.; Sanjuán-Nuñez, L.; Martín-Alvarez, A. B.; Martín-Oliva, D.; Caballero, T.; Muñoz de Rueda, P.; León, J.; Gonzalez, R.; Muntané, J.; Oliver, F.J.; Salmerón, J. Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression. Hepatology 2010, 51, 255-266.
-
(2010)
Hepatology
, vol.51
, pp. 255-266
-
-
Quiles-Perez, R.1
Muñoz-Gámez, J.A.2
Ruiz-Extremera, A.3
O'Valle, F.4
Sanjuán-Nuñez, L.5
Martín-Alvarez, A.B.6
Martín-Oliva, D.7
Caballero, T.8
Muñoz de Rueda, P.9
León, J.10
Gonzalez, R.11
Muntané, J.12
Oliver, F.J.13
Salmerón, J.14
-
118
-
-
0041409832
-
Effect of octreotide on angiogenesis induced by hepatocellular carcinoma in vivo
-
Jia, W. D.; Xu, G. L.; Sun, H. C.; Wang, L.; Xu, R. N.; Xue, Q. Effect of octreotide on angiogenesis induced by hepatocellular carcinoma in vivo. Hepatobiliary Pancreat. Dis. Int. 2003, 2, 404-409.
-
(2003)
Hepatobiliary Pancreat. Dis. Int
, vol.2
, pp. 404-409
-
-
Jia, W.D.1
Xu, G.L.2
Sun, H.C.3
Wang, L.4
Xu, R.N.5
Xue, Q.6
-
119
-
-
10744230216
-
Octreotide acts as an antitumor angiogenesis compound and suppresses tumor growth in nude mice bearing human hepatocellular carcinoma xenografts
-
Jia, W. D.; Xu, G. L.; Xu, R. N.; Sun, H. C.; Wang, L.; Yu, J. H.; Wang, J.; Li, J. S.; Zhai, Z. M.; Xue, Q. Octreotide acts as an antitumor angiogenesis compound and suppresses tumor growth in nude mice bearing human hepatocellular carcinoma xenografts. J. Cancer Res. Clin. Oncol. 2003, 129, 327-334.
-
(2003)
J. Cancer Res. Clin. Oncol
, vol.129
, pp. 327-334
-
-
Jia, W.D.1
Xu, G.L.2
Xu, R.N.3
Sun, H.C.4
Wang, L.5
Yu, J.H.6
Wang, J.7
Li, J.S.8
Zhai, Z.M.9
Xue, Q.10
-
120
-
-
71349084923
-
Efficacy of lanreotide in preventing the occurrence of chemically induced hepatocellular carcinoma in rats
-
Borbath, I.; Leclercq, I.A.; Sempoux, C.; Abarca-Quinones, J.; Desaeger, C.; Horsmans, Y. Efficacy of lanreotide in preventing the occurrence of chemically induced hepatocellular carcinoma in rats. Chem.-Biol. Interact. 2010, 183, 238-248.
-
(2010)
Chem.-Biol. Interact
, vol.183
, pp. 238-248
-
-
Borbath, I.1
Leclercq, I.A.2
Sempoux, C.3
Abarca-Quinones, J.4
Desaeger, C.5
Horsmans, Y.6
-
121
-
-
84857357820
-
Dovitinib demonstrates antitumor and antimetastatic activities in xenograft models of hepatocellular carcinoma
-
Huynh, H.; Chow, P. K.; Tai, W. M.; Choo, S. P.; Chung, A. Y.; Ong, H. S.; Soo, K. C.; Ong, R.; Linnartz, R.; Shi, M. M. Dovitinib demonstrates antitumor and antimetastatic activities in xenograft models of hepatocellular carcinoma. J. Hepatol. 2012, 56, 595-601.
-
(2012)
J. Hepatol
, vol.56
, pp. 595-601
-
-
Huynh, H.1
Chow, P.K.2
Tai, W.M.3
Choo, S.P.4
Chung, A.Y.5
Ong, H.S.6
Soo, K.C.7
Ong, R.8
Linnartz, R.9
Shi, M.M.10
-
122
-
-
84861535274
-
Foretinib demonstrates anti-tumor activity and improves overall survival in preclinical models of hepatocellular carcinoma
-
Huynh, H.; Ong, R.; Soo, K. C. Foretinib demonstrates anti-tumor activity and improves overall survival in preclinical models of hepatocellular carcinoma. Angiogenesis 2012, 15, 59-70.
-
(2012)
Angiogenesis
, vol.15
, pp. 59-70
-
-
Huynh, H.1
Ong, R.2
Soo, K.C.3
-
123
-
-
18144401256
-
Both antiangiogenesis-and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584
-
Liu, Y.; Poon, R. T.; Li, Q.; Kok, T. W.; Lau, C.; Fan, S. T. Both antiangiogenesis-and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584. Cancer Res. 2005, 65, 3691-3699.
-
(2005)
Cancer Res
, vol.65
, pp. 3691-3699
-
-
Liu, Y.1
Poon, R.T.2
Li, Q.3
Kok, T.W.4
Lau, C.5
Fan, S.T.6
-
124
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
Wilhelm, S. M.; Carter, C.; Tang, L.; Wilkie, D.; McNabola, A.; Rong, H.; Chen, C.; Zhang, X.; Vincent, P.; McHugh, M.; Cao, Y.; Shujath, J.; Gawlak, S.; Eveleigh, D.; Rowley, B.; Liu, L.; Adnane, L.; Lynch, M.; Auclair, D.; Taylor, I.; Gedrich, R.; Voznesensky, A.; Riedl, B.; Post, L. E.; Bollag, G.; Trail, P. A. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. 2004, 64, 7099-7109.
-
(2004)
Cancer Res
, vol.64
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
Wilkie, D.4
McNabola, A.5
Rong, H.6
Chen, C.7
Zhang, X.8
Vincent, P.9
McHugh, M.10
Cao, Y.11
Shujath, J.12
Gawlak, S.13
Eveleigh, D.14
Rowley, B.15
Liu, L.16
Adnane, L.17
Lynch, M.18
Auclair, D.19
Taylor, I.20
Gedrich, R.21
Voznesensky, A.22
Riedl, B.23
Post, L.E.24
Bollag, G.25
Trail, P.A.26
more..
-
125
-
-
33846212284
-
Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
-
Liu, L.; Cao, Y.; Chen, C.; Zhang, X.; McNabola, A.; Wilkie, D.; Wilhelm, S.; Lynch, M.; Carter, C. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. Cancer Res. 2006, 66, 11851-11858.
-
(2006)
Cancer Res
, vol.66
, pp. 11851-11858
-
-
Liu, L.1
Cao, Y.2
Chen, C.3
Zhang, X.4
McNabola, A.5
Wilkie, D.6
Wilhelm, S.7
Lynch, M.8
Carter, C.9
-
126
-
-
52649085241
-
Effect of rapamycin alone and in combination with sorafenib in an orthotopic model of human hepatocellular carcinoma
-
Wang, Z.; Zhou, J.; Fan, J.; Qiu, S. J.; Yu, Y.; Huang, X. W.; Tang, Z. Y. Effect of rapamycin alone and in combination with sorafenib in an orthotopic model of human hepatocellular carcinoma. Clin. Cancer Res. 2008, 14, 5124-5130.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 5124-5130
-
-
Wang, Z.1
Zhou, J.2
Fan, J.3
Qiu, S.J.4
Yu, Y.5
Huang, X.W.6
Tang, Z.Y.7
-
127
-
-
34548316976
-
Molecular basis for sunitinib efficacy and future clinical development
-
Faivre, S.; Demetri, G.; Sargent, W.; Raymond, E. Molecular basis for sunitinib efficacy and future clinical development. Nat. Rev. Drug Discov. 2007, 6, 734-745.
-
(2007)
Nat. Rev. Drug Discov
, vol.6
, pp. 734-745
-
-
Faivre, S.1
Demetri, G.2
Sargent, W.3
Raymond, E.4
-
128
-
-
70349158101
-
Sunitinib (SUTENT, SU11248) suppresses tumor growth and induces apoptosis in xenograft models of human hepatocellular carcinoma
-
Huynh, H.; Ngo, V. C.; Choo, S. P.; Poon, D.; Koong, H. N.; Thng, C. H.; Toh, H. C.; Zheng, L.; Ong, L. C.; Jin, Y.; Song, I. C.; Chang, A. P.; Ong, H. S.; Chung, A. Y.; Chow, P. K.; Soo, K. C. Sunitinib (SUTENT, SU11248) suppresses tumor growth and induces apoptosis in xenograft models of human hepatocellular carcinoma. Curr. Cancer Drug Targets 2009, 9, 738-747.
-
(2009)
Curr. Cancer Drug Targets
, vol.9
, pp. 738-747
-
-
Huynh, H.1
Ngo, V.C.2
Choo, S.P.3
Poon, D.4
Koong, H.N.5
Thng, C.H.6
Toh, H.C.7
Zheng, L.8
Ong, L.C.9
Jin, Y.10
Song, I.C.11
Chang, A.P.12
Ong, H.S.13
Chung, A.Y.14
Chow, P.K.15
Soo, K.C.16
-
129
-
-
2542523903
-
Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice
-
Yoshiji, H.; Kuriyama, S.; Yoshii, J.; Ikenaka, Y.; Noguchi, R.; Hicklin, D. J.; Wu, Y.; Yanase, K.; Namisaki, T.; Kitade, M.; Yamazaki, M.; Tsujinoue, H.; Masaki, T.; Fukui H. Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice. Hepatology 2004, 39, 1517-1524.
-
(2004)
Hepatology
, vol.39
, pp. 1517-1524
-
-
Yoshiji, H.1
Kuriyama, S.2
Yoshii, J.3
Ikenaka, Y.4
Noguchi, R.5
Hicklin, D.J.6
Wu, Y.7
Yanase, K.8
Namisaki, T.9
Kitade, M.10
Yamazaki, M.11
Tsujinoue, H.12
Masaki, T.13
Fukui, H.14
-
130
-
-
32844454531
-
Wnt/Frizzled signaling in hepatocellular carcinoma
-
Lee, H. C.; Kim, M.; Wands, J.R. Wnt/Frizzled signaling in hepatocellular carcinoma. Front. Biosci. 2006, 11, 1901-1915.
-
(2006)
Front. Biosci
, vol.11
, pp. 1901-1915
-
-
Lee, H.C.1
Kim, M.2
Wands, J.R.3
-
131
-
-
79952043062
-
Beta-catenin signaling, liver regeneration and hepatocellular cancer: Sorting the good from the bad
-
Nejak-Bowen, K. N.; Monga, S. P. Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad. Semin. Cancer Biol. 2011, 21, 44-58.
-
(2011)
Semin. Cancer Biol
, vol.21
, pp. 44-58
-
-
Nejak-Bowen, K.N.1
Monga, S.P.2
-
132
-
-
70149095242
-
Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma
-
Hu, J.; Dong, A.; Fernandez-Ruiz, V.; Shan, J.; Kawa, M.; Martínez-Ansó, E.; Prieto, J.; Qian, C. Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma. Cancer Res. 2009, 69, 6951-6959.
-
(2009)
Cancer Res
, vol.69
, pp. 6951-6959
-
-
Hu, J.1
Dong, A.2
Fernandez-Ruiz, V.3
Shan, J.4
Kawa, M.5
Martínez-Ansó, E.6
Prieto, J.7
Qian, C.8
-
133
-
-
76049087581
-
Suppression of liver tumor growth and metastasis by adiponectin in nude mice through inhibition of tumor angiogenesis and downregulation of Rho kinase/IFN-inducible protein 10/matrix metalloproteinase 9 signaling
-
Man, K.; Ng, K. T.; Xu, A.; Cheng, Q.; Lo, C. M.; Xiao, J. W.; Sun, B. S.; Lim, Z. X.; Cheung, J. S.; Wu, E. X.; Sun, C. K.; Poon, R. T.; Fan, S. T. Suppression of liver tumor growth and metastasis by adiponectin in nude mice through inhibition of tumor angiogenesis and downregulation of Rho kinase/IFN-inducible protein 10/matrix metalloproteinase 9 signaling. Clin. Cancer Res. 2010, 16, 967-977.
-
(2010)
Clin. Cancer Res
, vol.16
, pp. 967-977
-
-
Man, K.1
Ng, K.T.2
Xu, A.3
Cheng, Q.4
Lo, C.M.5
Xiao, J.W.6
Sun, B.S.7
Lim, Z.X.8
Cheung, J.S.9
Wu, E.X.10
Sun, C.K.11
Poon, R.T.12
Fan, S.T.13
-
134
-
-
33745936962
-
Opposing effects of arsenic trioxide on hepatocellular carcinomas in mice
-
Liu, B.; Pan, S.; Dong, X.; Qiao, H.; Jiang, H.; Krissansen, G. W.; Sun X. Opposing effects of arsenic trioxide on hepatocellular carcinomas in mice. Cancer Sci. 2006, 97, 675-681.
-
(2006)
Cancer Sci
, vol.97
, pp. 675-681
-
-
Liu, B.1
Pan, S.2
Dong, X.3
Qiao, H.4
Jiang, H.5
Krissansen, G.W.6
Sun, X.7
-
135
-
-
84862777172
-
Enhancement of hexokinase II inhibitor-induced apoptosis in hepatocellular carcinoma cells via augmenting ER stress and anti-angiogenesis by protein disulfide isomerase inhibition
-
Yu, S. J.; Yoon, J. H.; Yang, J. I., Cho, E. J.; Kwak, M. S.; Jang, E. S.; Lee, J. H.; Kim, Y. J.; Lee, H. S.; Kim, C. Y. Enhancement of hexokinase II inhibitor-induced apoptosis in hepatocellular carcinoma cells via augmenting ER stress and anti-angiogenesis by protein disulfide isomerase inhibition. J. Bioenerg. Biomembr. 2012, 44, 101-115.
-
(2012)
J. Bioenerg. Biomembr
, vol.44
, pp. 101-115
-
-
Yu, S.J.1
Yoon, J.H.2
Yang, J.I.3
Cho, E.J.4
Kwak, M.S.5
Jang, E.S.6
Lee, J.H.7
Kim, Y.J.8
Lee, H.S.9
Kim, C.Y.10
-
136
-
-
0027251836
-
A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts
-
Davies, B.; Brown, P. D.; East, N.; Crimmin, M. J.; Balkwill, F. R. A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts. Cancer Res. 1993, 53, 2087-2091.
-
(1993)
Cancer Res
, vol.53
, pp. 2087-2091
-
-
Davies, B.1
Brown, P.D.2
East, N.3
Crimmin, M.J.4
Balkwill, F.R.5
-
137
-
-
0031669587
-
Effects of matrix metalloproteinase inhibitor BB-94 on liver cancer growth and metastasis in a patient-like orthotopic model LCI-D20
-
Bu, W.; Tang, Z. Y.; Sun, F. X.; Ye, S. L.; Liu, K. D.; Xue, Q.; Chen, J.; Gao, D. M. Effects of matrix metalloproteinase inhibitor BB-94 on liver cancer growth and metastasis in a patient-like orthotopic model LCI-D20. Hepatogastroenterology 1998, 45, 1056-1061.
-
(1998)
Hepatogastroenterology
, vol.45
, pp. 1056-1061
-
-
Bu, W.1
Tang, Z.Y.2
Sun, F.X.3
Ye, S.L.4
Liu, K.D.5
Xue, Q.6
Chen, J.7
Gao, D.M.8
-
138
-
-
0038047688
-
Italian BCAA Study Group. Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: A double-blind, randomized trial
-
Marchesini, G.; Bianchi, G.; Merli, M.; Amodio, P.; Panella, C.; Loguercio, C.; Rossi Fanelli, F.; Abbiati, R.; Italian BCAA Study Group. Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial. Gastroenterology 2003, 124, 1792-1801.
-
(2003)
Gastroenterology
, vol.124
, pp. 1792-1801
-
-
Marchesini, G.1
Bianchi, G.2
Merli, M.3
Amodio, P.4
Panella, C.5
Loguercio, C.6
Rossi Fanelli, F.7
Abbiati, R.8
-
139
-
-
22144472524
-
Long-Term Survival Study Group. Effects of oral branched-chain amino acid granules on event-free survival in patients with liver cirrhosis
-
Muto, Y.; Sato, S.; Watanabe, A.; Moriwaki, H.; Suzuki, K.; Kato, A.; Kato, M.; Nakamura, T.; Higuchi, K.; Nishiguchi, S.; Kumada, H.; Long-Term Survival Study Group. Effects of oral branched-chain amino acid granules on event-free survival in patients with liver cirrhosis. Clin. Gastroenterol. Hepatol. 2005, 3, 705-713.
-
(2005)
Clin. Gastroenterol. Hepatol
, vol.3
, pp. 705-713
-
-
Muto, Y.1
Sato, S.2
Watanabe, A.3
Moriwaki, H.4
Suzuki, K.5
Kato, A.6
Kato, M.7
Nakamura, T.8
Higuchi, K.9
Nishiguchi, S.10
Kumada, H.11
-
140
-
-
67349195436
-
Branchedchain amino acids suppress insulin-resistance-based hepatocarcinogenesis in obese diabetic rats
-
Yoshiji, H,; Noguchi, R.; Kitade, M.; Kaji, K.; Ikenaka, Y.; Namisaki, T.; Yoshii, J.; Yanase, K.; Yamazaki, M.; Tsujimoto, T.; Akahane, T.; Kawaratani, H.; Uemura, M.; Fukui. H. Branchedchain amino acids suppress insulin-resistance-based hepatocarcinogenesis in obese diabetic rats. J. Gastroenterol. 2009, 44, 483-491.
-
(2009)
J. Gastroenterol
, vol.44
, pp. 483-491
-
-
Yoshiji, H.1
Noguchi, R.2
Kitade, M.3
Kaji, K.4
Ikenaka, Y.5
Namisaki, T.6
Yoshii, J.7
Yanase, K.8
Yamazaki, M.9
Tsujimoto, T.10
Akahane, T.11
Kawaratani, H.12
Uemura, M.13
Fukui, H.14
-
141
-
-
77953324172
-
Attenuation of insulin-resistance-based hepatocarcinogenesis and angiogenesis by combined treatment with branched-chain amino acids and angiotensin-converting enzyme inhibitor in obese diabetic rats
-
Yoshiji, H.; Noguchi, R.; Kaji, K.; Ikenaka, Y.; Shirai, Y.; Namisaki, T.; Kitade, M.; Tsujimoto, T.; Kawaratani, H.; Fukui, H. Attenuation of insulin-resistance-based hepatocarcinogenesis and angiogenesis by combined treatment with branched-chain amino acids and angiotensin-converting enzyme inhibitor in obese diabetic rats. J. Gastroenterol. 2010, 45, 443-450.
-
(2010)
J. Gastroenterol
, vol.45
, pp. 443-450
-
-
Yoshiji, H.1
Noguchi, R.2
Kaji, K.3
Ikenaka, Y.4
Shirai, Y.5
Namisaki, T.6
Kitade, M.7
Tsujimoto, T.8
Kawaratani, H.9
Fukui, H.10
-
142
-
-
0030759740
-
Halofuginone, a specific inhibitor of collagen type I synthesis, prevents dimethylnitrosamine-induced liver cirrhosis
-
Pines, M.; Knopov, V.; Genina, O.; Lavelin, I.; Nagler, A. Halofuginone, a specific inhibitor of collagen type I synthesis, prevents dimethylnitrosamine-induced liver cirrhosis. J. Hepatol. 1997, 27, 391-398.
-
(1997)
J. Hepatol
, vol.27
, pp. 391-398
-
-
Pines, M.1
Knopov, V.2
Genina, O.3
Lavelin, I.4
Nagler, A.5
-
143
-
-
0035142629
-
Halofuginone to prevent and treat thioacetamide-induced liver fibrosis in rats
-
Bruck, R.; Genina, O.; Aeed, H.; Alexiev, R.; Nagler, A.; Avni, Y.; Pines, M. Halofuginone to prevent and treat thioacetamide-induced liver fibrosis in rats. Hepatology 2001, 33, 379-386.
-
(2001)
Hepatology
, vol.33
, pp. 379-386
-
-
Bruck, R.1
Genina, O.2
Aeed, H.3
Alexiev, R.4
Nagler, A.5
Avni, Y.6
Pines, M.7
-
144
-
-
33646414772
-
Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition
-
Taras, D.; Blanc, J. F.; Rullier, A.; Dugot-Senant, N.; Laurendeau, I.; Bièche, I.; Pines, M.; Rosenbaum J. Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition. Neoplasia 2006, 8, 312-318.
-
(2006)
Neoplasia
, vol.8
, pp. 312-318
-
-
Taras, D.1
Blanc, J.F.2
Rullier, A.3
Dugot-Senant, N.4
Laurendeau, I.5
Bièche, I.6
Pines, M.7
Rosenbaum, J.8
-
145
-
-
0023636242
-
cDNA sequence of human apolipoprotein(a) is homologous to plasminogen
-
McLean, J. W.; Tomlinson, J. E.; Kuang, W. J.; Eaton, D. L.; Chen, E. Y.; Fless, G. M.; Scanu, A. M.; Lawn, R. M. cDNA sequence of human apolipoprotein(a) is homologous to plasminogen. Nature 1987, 330, 132-137.
-
(1987)
Nature
, vol.330
, pp. 132-137
-
-
McLean, J.W.1
Tomlinson, J.E.2
Kuang, W.J.3
Eaton, D.L.4
Chen, E.Y.5
Fless, G.M.6
Scanu, A.M.7
Lawn, R.M.8
-
146
-
-
0042206622
-
Inhibition of angiogenesis and angiogenesis-dependent tumor growth by the cryptic kringle fragments of human apolipoprotein(a)
-
Kim, J. S.; Chang, J. H.; Yu, H. K.; Ahn, J. H.; Yum, J. S.; Lee, S. K.; Jung, K. H.; Park, D. H.; Yoon, Y.; Byun, S. M.; Chung S. I. Inhibition of angiogenesis and angiogenesis-dependent tumor growth by the cryptic kringle fragments of human apolipoprotein(a). J. Biol. Chem. 2003, 278, 29000-29008.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 29000-29008
-
-
Kim, J.S.1
Chang, J.H.2
Yu, H.K.3
Ahn, J.H.4
Yum, J.S.5
Lee, S.K.6
Jung, K.H.7
Park, D.H.8
Yoon, Y.9
Byun, S.M.10
Chung, S.I.11
-
147
-
-
4944230455
-
Suppression of colorectal cancer liver metastasis and extension of survival by expression of apolipoprotein(a) kringles
-
Yu, H. K.; Kim, J. S.; Lee, H. J.; Ahn, J. H.; Lee, S. K.; Hong, S. W.; Yoon, Y. Suppression of colorectal cancer liver metastasis and extension of survival by expression of apolipoprotein(a) kringles. Cancer Res. 2004, 64, 7092-7098.
-
(2004)
Cancer Res
, vol.64
, pp. 7092-7098
-
-
Yu, H.K.1
Kim, J.S.2
Lee, H.J.3
Ahn, J.H.4
Lee, S.K.5
Hong, S.W.6
Yoon, Y.7
-
148
-
-
33646578180
-
Adenoassociated virus-mediated expression of apolipoprotein (a) kringles suppresses hepatocellular carcinoma growth in mice
-
Lee, K.; Yun, S. T.; Kim, Y. G.; Yoon, Y.; Jo, E. C. Adenoassociated virus-mediated expression of apolipoprotein (a) kringles suppresses hepatocellular carcinoma growth in mice. Hepatology 2006, 43, 1063-1073.
-
(2006)
Hepatology
, vol.43
, pp. 1063-1073
-
-
Lee, K.1
Yun, S.T.2
Kim, Y.G.3
Yoon, Y.4
Jo, E.C.5
-
149
-
-
0032910586
-
Effect of antiangiogenic agents on experimental animal models of hepatocarcinoma
-
Qin, L. X.; Tang, Z. Y.; Li, X. M.; Bu, W.; Xia, J. L. Effect of antiangiogenic agents on experimental animal models of hepatocarcinoma. Ann. Acad. Med. Singapore 1999, 28, 147-151.
-
(1999)
Ann. Acad. Med. Singapore
, vol.28
, pp. 147-151
-
-
Qin, L.X.1
Tang, Z.Y.2
Li, X.M.3
Bu, W.4
Xia, J.L.5
-
150
-
-
0028216334
-
Thalidomide is an inhibitor of angiogenesis
-
D'Amato, R. J.; Loughnan, M. S.; Flynn, E.; Folkman, J. Thalidomide is an inhibitor of angiogenesis. Proc. Natl. Acad. Sci. USA 1994, 91, 4082-4085.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4082-4085
-
-
D'Amato, R.J.1
Loughnan, M.S.2
Flynn, E.3
Folkman, J.4
-
151
-
-
12344321483
-
Effects of thalidomide on angiogenesis and tumor growth and metastasis of human hepatocellular carcinoma in nude mice
-
Zhang, Z. L.; Liu, Z. S.; Sun, Q. Effects of thalidomide on angiogenesis and tumor growth and metastasis of human hepatocellular carcinoma in nude mice. World J. Gastroenterol. 2005, 11, 216-220.
-
(2005)
World J. Gastroenterol
, vol.11
, pp. 216-220
-
-
Zhang, Z.L.1
Liu, Z.S.2
Sun, Q.3
-
152
-
-
77951873502
-
Delayed hepatocarcinogenesis through antiangiogenic intervention in the nuclear factor-kappa B activation pathway in rats
-
Dong, Z. Z.; Yao, D. F.; Wu, W.; Yao, M.; Yu, H. B.; Shen, J. J.; Qiu, L. W.; Yao, N. H.; Sai, W. L.; Yang, J. L. Delayed hepatocarcinogenesis through antiangiogenic intervention in the nuclear factor-kappa B activation pathway in rats. Hepatobiliary Pancreat. Dis. Int. 2010, 9, 169-174.
-
(2010)
Hepatobiliary Pancreat. Dis. Int
, vol.9
, pp. 169-174
-
-
Dong, Z.Z.1
Yao, D.F.2
Wu, W.3
Yao, M.4
Yu, H.B.5
Shen, J.J.6
Qiu, L.W.7
Yao, N.H.8
Sai, W.L.9
Yang, J.L.10
-
153
-
-
0020000982
-
Role of prostaglandin E1 and copper in angiogenesis
-
Ziche, M.; Jones, J.; Gullino, P. M. Role of prostaglandin E1 and copper in angiogenesis. J. Natl. Cancer Inst. 1982, 69, 475-482.
-
(1982)
J. Natl. Cancer Inst
, vol.69
, pp. 475-482
-
-
Ziche, M.1
Jones, J.2
Gullino, P.M.3
-
154
-
-
0029257122
-
MR imaging of hepatocellular carcinoma. Correlation of metal content and signal intensity
-
Honda, H.; Onitsuka, H.; Kanazawa, Y.; Matsumata, T.; Hayashi, T.; Kaneko, K.; Fukuya, T.; Tateshi, Y.; Adachi, E.; Masuda, K. MR imaging of hepatocellular carcinoma. Correlation of metal content and signal intensity. Acta Radiol. 1995, 36, 163-167.
-
(1995)
Acta Radiol
, vol.36
, pp. 163-167
-
-
Honda, H.1
Onitsuka, H.2
Kanazawa, Y.3
Matsumata, T.4
Hayashi, T.5
Kaneko, K.6
Fukuya, T.7
Tateshi, Y.8
Adachi, E.9
Masuda, K.10
-
155
-
-
0035892359
-
The copper-chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells
-
Yoshiji, J.; Yoshiji, H.; Kuriyama, S.; Ikenaka, Y.; Noguchi, R.; Okuda, H.; Tsujinoue, H.; Nakatani, T.; Kishida, H.; Nakae, D.; Gomez, D. E.; De Lorenzo, M. S.; Tejera, A. M.; Fukui, H. The copper-chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells. Int. J. Cancer 2001, 94, 768-773.
-
(2001)
Int. J. Cancer
, vol.94
, pp. 768-773
-
-
Yoshiji, J.1
Yoshiji, H.2
Kuriyama, S.3
Ikenaka, Y.4
Noguchi, R.5
Okuda, H.6
Tsujinoue, H.7
Nakatani, T.8
Kishida, H.9
Nakae, D.10
Gomez, D.E.11
de Lorenzo, M.S.12
Tejera, A.M.13
Fukui, H.14
-
156
-
-
2142802120
-
The copper-chelating agent, trientine, attenuates liver enzyme-altered preneoplastic lesions in rats by angiogenesis suppression
-
Yoshiji, H.; Kuriyama, S.; Yoshii, J.; Ikenaka, Y.; Noguchi, R.; Yanase, K.; Namisaki, T.; Yamazaki, M.; Tsujinoue, H.; Imazu, H.; Fukui, H. The copper-chelating agent, trientine, attenuates liver enzyme-altered preneoplastic lesions in rats by angiogenesis suppression. Oncol. Rep. 2003, 10, 1369-1373.
-
(2003)
Oncol. Rep
, vol.10
, pp. 1369-1373
-
-
Yoshiji, H.1
Kuriyama, S.2
Yoshii, J.3
Ikenaka, Y.4
Noguchi, R.5
Yanase, K.6
Namisaki, T.7
Yamazaki, M.8
Tsujinoue, H.9
Imazu, H.10
Fukui, H.11
-
157
-
-
0037058676
-
The copper chelator trientine has an antiangiogenic effect against hepatocellular carcinoma, possibly through inhibition of interleukin-8 production
-
Moriguchi, M.; Nakajima, T.; Kimura, H.; Watanabe, T.; Takashima, H.; Mitsumoto, Y.; Katagishi, T.; Okanoue, T.; Kagawa, K. The copper chelator trientine has an antiangiogenic effect against hepatocellular carcinoma, possibly through inhibition of interleukin-8 production. Int. J. Cancer 2002, 102, 445-452.
-
(2002)
Int. J. Cancer
, vol.102
, pp. 445-452
-
-
Moriguchi, M.1
Nakajima, T.2
Kimura, H.3
Watanabe, T.4
Takashima, H.5
Mitsumoto, Y.6
Katagishi, T.7
Okanoue, T.8
Kagawa, K.9
-
158
-
-
0037446897
-
Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins
-
Sudhakar, A.; Sugimoto, H.; Yang, C.; Lively, J.; Zeisberg, M.; Kalluri, R. Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins. Proc. Natl. Acad. Sci. USA 2003, 100, 4766-4771.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4766-4771
-
-
Sudhakar, A.1
Sugimoto, H.2
Yang, C.3
Lively, J.4
Zeisberg, M.5
Kalluri, R.6
-
159
-
-
51049083190
-
Tum-1, a tumstatin fragment, gene delivery into hepatocellular carcinoma suppresses tumor growth through inhibiting angiogenesis
-
Goto, T.; Ishikawa, H.; Matsumoto, K.; Nishimura, D.; Kusaba, M.; Taura, N.; Shibata, H.; Miyaaki, H.; Ichikawa, T.; Hamasaki, K.; Nakao, K.; Maeshima, Y.; Eguchi, K. Tum-1, a tumstatin fragment, gene delivery into hepatocellular carcinoma suppresses tumor growth through inhibiting angiogenesis. Int. J. Oncol. 2008, 33, 33-40.
-
(2008)
Int. J. Oncol
, vol.33
, pp. 33-40
-
-
Goto, T.1
Ishikawa, H.2
Matsumoto, K.3
Nishimura, D.4
Kusaba, M.5
Taura, N.6
Shibata, H.7
Miyaaki, H.8
Ichikawa, T.9
Hamasaki, K.10
Nakao, K.11
Maeshima, Y.12
Eguchi, K.13
-
160
-
-
77950462129
-
Chemopreventive effect of bacoside A on N-nitrosodiethylamineinduced hepatocarcinogenesis in rats
-
Janani, P.; Sivakumari, K.; Geetha, A.; Ravisankar, B.; Parthasarathy, C. Chemopreventive effect of bacoside A on N-nitrosodiethylamineinduced hepatocarcinogenesis in rats. J. Cancer Res. Clin. Oncol. 2010, 136, 759-770.
-
(2010)
J. Cancer Res. Clin. Oncol
, vol.136
, pp. 759-770
-
-
Janani, P.1
Sivakumari, K.2
Geetha, A.3
Ravisankar, B.4
Parthasarathy, C.5
-
161
-
-
77249140494
-
Bacoside A downregulates matrix metalloproteinases 2 and 9 in DENA-induced hepatocellular carcinoma
-
Janani, P.; Sivakumari, K.; Geetha, A.; Ravisankar, B.; Parthasarathy, C. Bacoside A downregulates matrix metalloproteinases 2 and 9 in DENA-induced hepatocellular carcinoma. Cell Biochem. Funct. 2010, 28, 164-169.
-
(2010)
Cell Biochem. Funct
, vol.28
, pp. 164-169
-
-
Janani, P.1
Sivakumari, K.2
Geetha, A.3
Ravisankar, B.4
Parthasarathy, C.5
-
162
-
-
0033015577
-
Food applications of chitin and chitosan
-
Shahidi, F.; Arachchi, J.K.V.; Jeon, Y. J. Food applications of chitin and chitosan. Trends Food Sci. Tech. 1999, 10, 37-51.
-
(1999)
Trends Food Sci. Tech
, vol.10
, pp. 37-51
-
-
Shahidi, F.1
Arachchi, J.K.V.2
Jeon, Y.J.3
-
163
-
-
75149149835
-
Chitosan nanoparticles inhibit the growth of human hepatocellular carcinoma xenografts through an antiangiogenic mechanism
-
Xu, Y.; Wen, Z.; Xu, Z. Chitosan nanoparticles inhibit the growth of human hepatocellular carcinoma xenografts through an antiangiogenic mechanism. Anticancer Res. 2010, 30, 5103-5110.
-
(2010)
Anticancer Res
, vol.30
, pp. 5103-5110
-
-
Xu, Y.1
Wen, Z.2
Xu, Z.3
-
164
-
-
24344503047
-
Antiangiogenic activity of curcumin in hepatocellular carcinoma cells implanted nude mice
-
Yoysungnoen, P.; Wirachwong, P.; Bhattarakosol, P.; Niimi, H.; Patumraj, S. Antiangiogenic activity of curcumin in hepatocellular carcinoma cells implanted nude mice. Clin. Hemorheol. Microcirc. 2005, 33, 127-135.
-
(2005)
Clin. Hemorheol. Microcirc
, vol.33
, pp. 127-135
-
-
Yoysungnoen, P.1
Wirachwong, P.2
Bhattarakosol, P.3
Niimi, H.4
Patumraj, S.5
-
165
-
-
33644797877
-
Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice
-
Yoysungnoen, P.; Wirachwong, P.; Bhattarakosol, P.; Niimi, H.; Patumraj, S.; Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice. Clin. Hemorheol. Microcirc. 2006, 34, 109-115.
-
(2006)
Clin. Hemorheol. Microcirc
, vol.34
, pp. 109-115
-
-
Yoysungnoen, P.1
Wirachwong, P.2
Bhattarakosol, P.3
Niimi, H.4
Patumraj, S.5
-
166
-
-
44849122833
-
Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice
-
Yoysungnoen, P.; Wirachwong, P.; Changtam, C.; Suksamrarn, A.; Patumraj S. Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice. World J. Gasterenterol. 2008, 14, 2003-2009.
-
(2008)
World J. Gasterenterol
, vol.14
, pp. 2003-2009
-
-
Yoysungnoen, P.1
Wirachwong, P.2
Changtam, C.3
Suksamrarn, A.4
Patumraj, S.5
-
167
-
-
70349585440
-
(-)-Epigallocatechin gallate suppresses the growth of human hepatocellular carcinoma cells by inhibiting activation of the vascular endothelial growth factor-vascular endothelial growth factor receptor axis
-
Shirakami, Y.; Shimizu, M.; Adachi, S.; Sakai, H.; Nakagawa, T.; Yasuda, Y.; Tsurumi, H.; Hara, Y.; Moriwaki, H. (-)-Epigallocatechin gallate suppresses the growth of human hepatocellular carcinoma cells by inhibiting activation of the vascular endothelial growth factor-vascular endothelial growth factor receptor axis. Cancer Sci. 2009, 10, 1957-1962.
-
(2009)
Cancer Sci
, vol.10
, pp. 1957-1962
-
-
Shirakami, Y.1
Shimizu, M.2
Adachi, S.3
Sakai, H.4
Nakagawa, T.5
Yasuda, Y.6
Tsurumi, H.7
Hara, Y.8
Moriwaki, H.9
-
168
-
-
24944575266
-
Comparative evaluation of the chemopreventive efficacy of green and black tea polyphenols in the hamster buccal pouch carcinogenesis model
-
Chandra Mohan, K. V.; Hara, Y.; Abraham, S. K.; Nagini, S. Comparative evaluation of the chemopreventive efficacy of green and black tea polyphenols in the hamster buccal pouch carcinogenesis model. Clin. Biochem. 2005, 38, 879-886.
-
(2005)
Clin. Biochem
, vol.38
, pp. 879-886
-
-
Chandra Mohan, K.V.1
Hara, Y.2
Abraham, S.K.3
Nagini, S.4
-
169
-
-
67650886038
-
Black tea polyphenols target matrix metalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model
-
Murugan, R. S.; Vinothini, G.; Hara, Y.; Nagini S. Black tea polyphenols target matrix metalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model. Anticancer Res. 2009, 29, 2301-2305.
-
(2009)
Anticancer Res
, vol.29
, pp. 2301-2305
-
-
Murugan, R.S.1
Vinothini, G.2
Hara, Y.3
Nagini, S.4
-
170
-
-
31344441221
-
Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis
-
Gu, Y.; Zhu, C.; Iwamoto, H.; Chen, J. S.; Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis. World J. Gasteroenterol. 2005, 11, 6512-5517.
-
(2005)
World J. Gasteroenterol
, vol.11
, pp. 5517-6512
-
-
Gu, Y.1
Zhu, C.2
Iwamoto, H.3
Chen, J.S.4
-
171
-
-
78650582952
-
Genistein potentiates the effect of arsenic trioxide against human hepatocellular carcinoma: Role of Akt and nuclear factor-κB
-
Ma, Y.; Wang, J.; Liu, L.; Zhu, H.; Chen, X.; Pan, S.; Sun, X.; Jiang, H. Genistein potentiates the effect of arsenic trioxide against human hepatocellular carcinoma: role of Akt and nuclear factor-κB. Cancer Lett. 2011, 301, 75-84.
-
(2011)
Cancer Lett
, vol.301
, pp. 75-84
-
-
Ma, Y.1
Wang, J.2
Liu, L.3
Zhu, H.4
Chen, X.5
Pan, S.6
Sun, X.7
Jiang, H.8
-
172
-
-
36549001577
-
Attenuation of N-nitrosodiethylamine-induced hepatocellular carcinogenesis by a novel flavonol-Morin
-
Sivaramakrishnan, V.; Shilpa, P. N.; Praveen Kumar, V. R.; Niranjali Devaraj, S. Attenuation of N-nitrosodiethylamine-induced hepatocellular carcinogenesis by a novel flavonol-Morin. Chem.-Biol. Interact. 2008, 171, 79-88.
-
(2008)
Chem.-Biol. Interact
, vol.171
, pp. 79-88
-
-
Sivaramakrishnan, V.1
Shilpa, P.N.2
Praveen Kumar, V.R.3
Niranjali Devaraj, S.4
-
173
-
-
67349224725
-
Morin regulates the expression of NF-B-p65, COX-2 and matrix metalloproteinases in diethylnitrosamine induced rat hepatocellular carcinoma
-
Sivaramakrishnan, V.; Devaraj, S. N. Morin regulates the expression of NF-B-p65, COX-2 and matrix metalloproteinases in diethylnitrosamine induced rat hepatocellular carcinoma. Chem.-Biol. Interact. 2009, 180, 353-359.
-
(2009)
Chem.-Biol. Interact
, vol.180
, pp. 353-359
-
-
Sivaramakrishnan, V.1
Devaraj, S.N.2
-
174
-
-
33744795150
-
Liposomal quercetin efficiently suppresses growth of solid tumors in murine models
-
Yuan, Z. P.; Chen, L. J.; Fan, L. Y.; Tang, M. H.; Yang, G. L.; Yang, H. S.; Du, X. B.; Wang, G. Q.; Yao, W. X.; Zhao, Q. M.; Ye, B.; Wang, R; Diao, P.; Zhang, W.; Wu, H. B.; Zhao, X.; Wei, Y. Q. Liposomal quercetin efficiently suppresses growth of solid tumors in murine models. Clin. Cancer Res. 2006, 12, 3193-3199.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 3193-3199
-
-
Yuan, Z.P.1
Chen, L.J.2
Fan, L.Y.3
Tang, M.H.4
Yang, G.L.5
Yang, H.S.6
Du, X.B.7
Wang, G.Q.8
Yao, W.X.9
Zhao, Q.M.10
Ye, B.11
Wang, R.12
Diao, P.13
Zhang, W.14
Wu, H.B.15
Zhao, X.16
Wei, Y.Q.17
-
175
-
-
62549154478
-
Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: Inhibition of cell proliferation and induction of apoptosis
-
Bishayee, A.; Dhir, N. Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis. Chem. Biol. Interact. 2009, 10, 131-144.
-
(2009)
Chem. Biol. Interact
, vol.10
, pp. 131-144
-
-
Bishayee, A.1
Dhir, N.2
-
176
-
-
77953229913
-
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis
-
Bishayee, A.; Barnes, K. F.; Bhatia, D.; Darvesh, A. S.; Carroll, R.T. Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis. Cancer Prev. Res. 2010, 3, 753-763.
-
(2010)
Cancer Prev. Res
, vol.3
, pp. 753-763
-
-
Bishayee, A.1
Barnes, K.F.2
Bhatia, D.3
Darvesh, A.S.4
Carroll, R.T.5
-
177
-
-
77953231047
-
Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis
-
Bishayee, A.; Waghray, A.; Barnes, K. F.; Mbimba T.; Bhatia D.; Chatterjee, M.; Darvesh, A. S. Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis. Pharm. Res. 2010, 27, 1080-1091.
-
(2010)
Pharm. Res
, vol.27
, pp. 1080-1091
-
-
Bishayee, A.1
Waghray, A.2
Barnes, K.F.3
Mbimba, T.4
Bhatia, D.5
Chatterjee, M.6
Darvesh, A.S.7
-
178
-
-
79251543646
-
Resveratrol inhibits VEGF expression of human hepatocellular carcinoma cells through a NF-B-mediated mechanism
-
Yu, H. B.; Zhang, H. F.; Zhang, X.; Li, D. Y.; Xue, H.Z.; Pan, C. E.; Zhao, S. H. Resveratrol inhibits VEGF expression of human hepatocellular carcinoma cells through a NF-B-mediated mechanism. Hepato-Gastroenterology 2010, 57, 1241-1246.
-
(2010)
Hepato-Gastroenterology
, vol.57
, pp. 1241-1246
-
-
Yu, H.B.1
Zhang, H.F.2
Zhang, X.3
Li, D.Y.4
Xue, H.Z.5
Pan, C.E.6
Zhao, S.H.7
-
179
-
-
77951663321
-
Selenium in the prevention and treatment of hepatocellular carcinoma
-
Darvesh, A. S.; Bishayee, A. Selenium in the prevention and treatment of hepatocellular carcinoma. Anti-Cancer Agents Med. Chem. 2010, 10, 338-345.
-
(2010)
Anti-Cancer Agents Med. Chem
, vol.10
, pp. 338-345
-
-
Darvesh, A.S.1
Bishayee, A.2
-
181
-
-
33645419548
-
Effect of seleniumenriched malt on hepatocarcinogenesis, paraneoplastic syndrome and the hormones regulating blood glucose in rats treated by diethylnitrosamine
-
Liu, J. G.; Zhao, H. J.; Liu, Y. J.; Wang, X. L. Effect of seleniumenriched malt on hepatocarcinogenesis, paraneoplastic syndrome and the hormones regulating blood glucose in rats treated by diethylnitrosamine. Life Sci. 2006, 78, 2315-2321.
-
(2006)
Life Sci
, vol.78
, pp. 2315-2321
-
-
Liu, J.G.1
Zhao, H.J.2
Liu, Y.J.3
Wang, X.L.4
-
182
-
-
73449102474
-
Effect of seleniumenriched malt on VEGF and several relevant angiogenic cytokines in diethylnitrosamine-induced hepatocarcinoma rats
-
Liu, J. G.; Zhao, H. J.; Liu, Y.J.; Wang, X. L. Effect of seleniumenriched malt on VEGF and several relevant angiogenic cytokines in diethylnitrosamine-induced hepatocarcinoma rats. J. Trace Elem. Med. Biol. 2010, 24, 52-57.
-
(2010)
J. Trace Elem. Med. Biol
, vol.24
, pp. 52-57
-
-
Liu, J.G.1
Zhao, H.J.2
Liu, Y.J.3
Wang, X.L.4
-
183
-
-
84868205248
-
Effect of two selenium sources on hepatocarcinogenesis and several angiogenic cytokines in diethylnitrosamine-induced hepatocarcinoma rats
-
in press. PMID: 22425635
-
Liu, J. G.; Zhao, H. J.; Liu, Y. J.; Liu, Y. W.; Wang, X. L. Effect of two selenium sources on hepatocarcinogenesis and several angiogenic cytokines in diethylnitrosamine-induced hepatocarcinoma rats. J. Trace Elem. Med. Biol. 2012, in press. PMID: 22425635
-
(2012)
J. Trace Elem. Med. Biol
-
-
Liu, J.G.1
Zhao, H.J.2
Liu, Y.J.3
Liu, Y.W.4
Wang, X.L.5
-
184
-
-
33646828371
-
Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats
-
Ramakrishnan, G.; Raghavendran, H. R.; Vinodhkumar, R.; Devaki, T. Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats. Chem. Biol. Interact. 2006, 161, 104-114.
-
(2006)
Chem. Biol. Interact
, vol.161
, pp. 104-114
-
-
Ramakrishnan, G.1
Raghavendran, H.R.2
Vinodhkumar, R.3
Devaki, T.4
-
185
-
-
44449096507
-
Silymarin downregulates COX-2 expression and attenuates hyperlipidemia during NDEAinduced rat hepatocellular carcinoma
-
Ramakrishnan, G.; Elinos-Báez, C. M.; Jagan, S.; Augustine, T. A.; Kamaraj, S.; Anandakumar, P.; Devaki T. Silymarin downregulates COX-2 expression and attenuates hyperlipidemia during NDEAinduced rat hepatocellular carcinoma. Mol. Cell. Biochem. 2008, 313, 53-61.
-
(2008)
Mol. Cell. Biochem
, vol.313
, pp. 53-61
-
-
Ramakrishnan, G.1
Elinos-Báez, C.M.2
Jagan, S.3
Augustine, T.A.4
Kamaraj, S.5
Anandakumar, P.6
Devaki, T.7
-
186
-
-
64649086559
-
Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis
-
Ramakrishnan, G.; Jagan, S.; Kamaraj, S.; Anandakumar, P.; Devaki, T. Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis. Invest. New Drugs 2009, 27, 233-240.
-
(2009)
Invest. New Drugs
, vol.27
, pp. 233-240
-
-
Ramakrishnan, G.1
Jagan, S.2
Kamaraj, S.3
Anandakumar, P.4
Devaki, T.5
-
187
-
-
0030856731
-
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
-
Presta, L. G.; Chen, H.; O'Conner, S. J.; Chisholm, V.; Meng, Y. G.; Krummen, L.; Winkler, M.; Ferrara, N. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res. 1997, 57, 4593-4599.
-
(1997)
Cancer Res
, vol.57
, pp. 4593-4599
-
-
Presta, L.G.1
Chen, H.2
O'Conner, S.J.3
Chisholm, V.4
Meng, Y.G.5
Krummen, L.6
Winkler, M.7
Ferrara, N.8
-
188
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colon cancer
-
Hurwitz, H.; Fenrenbacher, L.; Novotny, W.; Cartwright, T.; Hainsworth, J.; Heim, W.; Berlin, J.; Baron, A.; Griffing, S.; Holmgren, E.; Ferrara, N.; Fyfe, G.; Rogers, B.; Ross, R.; Kabbinavar, F. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colon cancer. N. Engl. J. Med. 2004, 350, 2335-2342.
-
(2004)
N. Engl. J. Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fenrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
189
-
-
46449091500
-
Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma
-
Siegel, A. B.; Cohen, E. I.; Ocean, A.; Lehrer, D.; Goldenberg, A.; Knox, J. J.; Chen, H.; Clark-Garvey, S.; Weinberg, A.; Mandeli, J.; Christos, P.; Mazumdar, M.; Popa, E.; Brown, R. S. Jr; Rafii, S.; Schwartz, J. D. Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma. J. Clin. Oncol. 2008, 26, 2992-2998.
-
(2008)
J. Clin. Oncol
, vol.26
, pp. 2992-2998
-
-
Siegel, A.B.1
Cohen, E.I.2
Ocean, A.3
Lehrer, D.4
Goldenberg, A.5
Knox, J.J.6
Chen, H.7
Clark-Garvey, S.8
Weinberg, A.9
Mandeli, J.10
Christos, P.11
Mazumdar, M.12
Popa, E.13
Brown Jr., R.S.14
Rafii, S.15
Schwartz, J.D.16
-
190
-
-
33646351795
-
Phase II study of gemcitabine and oxaliplatin in combination with benacizumab in patients with advanced hepatocellular carcinoma
-
Zhu, A. X.; Blaszkowsky, L. S.; Ryan, D. P.; Clark, J. W.; Muzikansky, A.; Horgan, K.; Sheehan, S.; Hale, K. E.; Enzinger, P. C.; Bhargava, P.; Stuart, K. Phase II study of gemcitabine and oxaliplatin in combination with benacizumab in patients with advanced hepatocellular carcinoma. J. Clin. Oncol. 2006, 24, 1898-1903.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 1898-1903
-
-
Zhu, A.X.1
Blaszkowsky, L.S.2
Ryan, D.P.3
Clark, J.W.4
Muzikansky, A.5
Horgan, K.6
Sheehan, S.7
Hale, K.E.8
Enzinger, P.C.9
Bhargava, P.10
Stuart, K.11
-
191
-
-
40349112983
-
Early antiangiogenic activity of bevacizumab evaluated by computed tomography perfusion scan in patients with advanced hepatocellular carcinoma
-
Zhu, A. X.; Holalkere, N. S.; Muzikansky, A.; Horgan, K.; Sahani, D. V. Early antiangiogenic activity of bevacizumab evaluated by computed tomography perfusion scan in patients with advanced hepatocellular carcinoma. Oncologist 2008, 13, 120-125.
-
(2008)
Oncologist
, vol.13
, pp. 120-125
-
-
Zhu, A.X.1
Holalkere, N.S.2
Muzikansky, A.3
Horgan, K.4
Sahani, D.V.5
-
192
-
-
60549098640
-
Sorafenib: A review of its use in advanced hepatocellular carcinoma
-
Keating, G. M.; Santoro, A. Sorafenib: a review of its use in advanced hepatocellular carcinoma. Drugs 2009, 69, 223-240.
-
(2009)
Drugs
, vol.69
, pp. 223-240
-
-
Keating, G.M.1
Santoro, A.2
-
193
-
-
34247857540
-
Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: A review of four phase I trials in patients with advanced refractory solid tumors
-
Strumberg, D.; Clark, J. W.; Awada, A.; Moore, M. J.; Richly, H.; Hendlisz, A.; Hirte, A. W.; Eder, J. P.; Lenz, H. J.; Schwartz, B. Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: a review of four phase I trials in patients with advanced refractory solid tumors. Oncologist 2007, 12, 426-437.
-
(2007)
Oncologist
, vol.12
, pp. 426-437
-
-
Strumberg, D.1
Clark, J.W.2
Awada, A.3
Moore, M.J.4
Richly, H.5
Hendlisz, A.6
Hirte, A.W.7
Eder, J.P.8
Lenz, H.J.9
Schwartz, B.10
-
194
-
-
33749017926
-
Phase II study of sarafenib in patients with advanced hepatocellular carcinoma
-
Abou-Alfa, G. K.; Schwartz, L.; Ricci, S.; Amadori, D.; Santoro, A.; Figer, A.; De Greve, J.; Douillard, J. Y.; Lathia, C.; Schwartz, B.; Taylor, I.; Moscovici, M.; Saltz, L. B. Phase II study of sarafenib in patients with advanced hepatocellular carcinoma. J. Clin. Oncol. 2006, 24, 4293-4300.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 4293-4300
-
-
Abou-Alfa, G.K.1
Schwartz, L.2
Ricci, S.3
Amadori, D.4
Santoro, A.5
Figer, A.6
de Greve, J.7
Douillard, J.Y.8
Lathia, C.9
Schwartz, B.10
Taylor, I.11
Moscovici, M.12
Saltz, L.B.13
-
195
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
SHARP Investigators Study Group
-
Llovet, J. M.; Ricci, S.; Mazzaferro, V.; Hilgard, P.; Gane, E.; Blanc, J. F.; de Oliveira, A. C.; Santaro, A.; Raoul, J. L.; Forner, A.; Schwartz, M.; Porta, C.; Zeuzem, S.; Bolondi, L.; Greten, T. F.; Galle, P. R.; Seitz, J. F.; Borbath, I.; Haussinger, D.; Giannaris, T.; Shan, M.; Moscovici, M.; Voliotis, D.; Bruix, J; SHARP Investigators Study Group. Sorafenib in advanced hepatocellular carcinoma. N. Engl. J. Med. 2008, 359, 378-379.
-
(2008)
N. Engl. J. Med
, vol.359
, pp. 378-379
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
Blanc, J.F.6
de Oliveira, A.C.7
Santaro, A.8
Raoul, J.L.9
Forner, A.10
Schwartz, M.11
Porta, C.12
Zeuzem, S.13
Bolondi, L.14
Greten, T.F.15
Galle, P.R.16
Seitz, J.F.17
Borbath, I.18
Haussinger, D.19
Giannaris, T.20
Shan, M.21
Moscovici, M.22
Voliotis, D.23
Bruix, J.24
more..
-
196
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomized, double-blind, placebo-controlled trial
-
Cheng, A. L.; Kang, Y. K.; Chen, Z.; Tsao, C. J.; Qin, S.; Kim, J.S.; Luo, R.; Feng, J.; Ye, S.; Yang, T.S.; Xu, J.; Sun, Y.; Liang, H.; Liu, J.; Wang, J.; Tak, W. Y.; Pan, H.; Burock, K.; Zou, J.; Voliotis, D.; Guan, Z. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomized, double-blind, placebo-controlled trial. Lancet Oncol. 2009, 10, 25-34.
-
(2009)
Lancet Oncol
, vol.10
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
Tsao, C.J.4
Qin, S.5
Kim, J.S.6
Luo, R.7
Feng, J.8
Ye, S.9
Yang, T.S.10
Xu, J.11
Sun, Y.12
Liang, H.13
Liu, J.14
Wang, J.15
Tak, W.Y.16
Pan, H.17
Burock, K.18
Zou, J.19
Voliotis, D.20
Guan, Z.21
more..
-
197
-
-
73349110120
-
Sunitinib in hepatocellular carcinoma: Redefining appropriate dosing, schedule, and activity end points
-
Faivre, S. J.; Bouattour, M.; Dreyer, C.; Raymond, E. Sunitinib in hepatocellular carcinoma: redefining appropriate dosing, schedule, and activity end points. J. Clin. Oncol. 2009, 27, 248-252.
-
(2009)
J. Clin. Oncol
, vol.27
, pp. 248-252
-
-
Faivre, S.J.1
Bouattour, M.2
Dreyer, C.3
Raymond, E.4
-
198
-
-
67649946279
-
Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: A phase II study
-
Zhu, A. X.; Sahani, D. V.; Duda, D. G.; di Tomaso, E.; Ancukiewicz, M.; Catalano, O. A.; Sindhwani, V.; Blaszkowsky, L. S.; Yoon, S. S.; Lahdenranta, J.; Bhargava, P.; Meyerhardt, J.; Clark, J. W.; Kwak, E. L.; Hezel, A. F.; Miksad, R.; Abrams, T. A.; Enzinger, P. C.; Fuchs, C. S.; Ryan, D. P.; Jain, R. K. Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study. J. Clin. Oncol. 2009, 27, 3027-3035.
-
(2009)
J. Clin. Oncol
, vol.27
, pp. 3027-3035
-
-
Zhu, A.X.1
Sahani, D.V.2
Duda, D.G.3
di Tomaso, E.4
Ancukiewicz, M.5
Catalano, O.A.6
Sindhwani, V.7
Blaszkowsky, L.S.8
Yoon, S.S.9
Lahdenranta, J.10
Bhargava, P.11
Meyerhardt, J.12
Clark, J.W.13
Kwak, E.L.14
Hezel, A.F.15
Miksad, R.16
Abrams, T.A.17
Enzinger, P.C.18
Fuchs, C.S.19
Ryan, D.P.20
Jain, R.K.21
more..
-
199
-
-
69549131042
-
Development of sunitinib in hepatocellular carcinoma: Rationale, early clinical experience, and correlative studies
-
Zhu, A. X.; Duda, D. G.; Sahani, D. V.; Jain, R. K. Development of sunitinib in hepatocellular carcinoma: rationale, early clinical experience, and correlative studies. Cancer J. 2009, 5, 263-268.
-
(2009)
Cancer J
, vol.5
, pp. 263-268
-
-
Zhu, A.X.1
Duda, D.G.2
Sahani, D.V.3
Jain, R.K.4
-
200
-
-
67651165187
-
Safety and efficacy of sunitinib in patients with advanced hepatocellular carcinoma: An open-label, multicenter, phase II study
-
Faivre, S.; Raymond, E.; Boucher, E.; Douillard, J.; Lim, H. Y.; Kim, J. S.; Zappa, M.; Lanzalone, S.; Lin, X.; Deprimo, S.; Harmon, C.; Ruiz-Garcia, A.; Lechuga, M. J.; Cheng, A. L. Safety and efficacy of sunitinib in patients with advanced hepatocellular carcinoma: an open-label, multicenter, phase II study. Lancet Oncol. 2009, 10, 794-800.
-
(2009)
Lancet Oncol
, vol.10
, pp. 794-800
-
-
Faivre, S.1
Raymond, E.2
Boucher, E.3
Douillard, J.4
Lim, H.Y.5
Kim, J.S.6
Zappa, M.7
Lanzalone, S.8
Lin, X.9
Deprimo, S.10
Harmon, C.11
Ruiz-Garcia, A.12
Lechuga, M.J.13
Cheng, A.L.14
-
201
-
-
0037099598
-
PTK787/ZK222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging
-
Drevs, J.; Muller-Driver, R.; Wittig, C.; Fuxius, S.; Esser, N.; Hugenschmidt, H.; Konerding, M. A.; Allergrini, P. R.; Wood, J.; Hennig, J.; Unger, C.; Marme, D. PTK787/ZK222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging. Cancer Res. 2002, 62, 4015-4022.
-
(2002)
Cancer Res
, vol.62
, pp. 4015-4022
-
-
Drevs, J.1
Muller-Driver, R.2
Wittig, C.3
Fuxius, S.4
Esser, N.5
Hugenschmidt, H.6
Konerding, M.A.7
Allergrini, P.R.8
Wood, J.9
Hennig, J.10
Unger, C.11
Marme, D.12
-
202
-
-
18144401256
-
Both antiangiogenesis-and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584
-
Liu, Y.; Poon, R. T.; Li, Q.; Kok, T. W.; Lau, C.; Fan, S. T. Both antiangiogenesis-and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584. Cancer Res. 2005, 65, 3691-3699.
-
(2005)
Cancer Res
, vol.65
, pp. 3691-3699
-
-
Liu, Y.1
Poon, R.T.2
Li, Q.3
Kok, T.W.4
Lau, C.5
Fan, S.T.6
-
203
-
-
20444473802
-
Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumors
-
Mross, K.; Drevs, J.; Muller, M.; Medinger, M.; Marme, D.; Henng, J.; Morgan, B.; Lebwohl, D.; Masson, E.; Ho, Y.Y.; Gunther, C.; Laurent, D.; Unger, C. Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumors. Eur. J. Cancer 2005, 41, 1291-1299.
-
(2005)
Eur. J. Cancer
, vol.41
, pp. 1291-1299
-
-
Mross, K.1
Drevs, J.2
Muller, M.3
Medinger, M.4
Marme, D.5
Henng, J.6
Morgan, B.7
Lebwohl, D.8
Masson, E.9
Ho, Y.Y.10
Gunther, C.11
Laurent, D.12
Unger, C.13
-
204
-
-
39849106728
-
Influence of hepatic dysfunction on safety, tolerability, and pharmacokinetics (PK) of PTK787/ZK222584 in patients with unresectable hepatocellular carcinoma
-
Koch, I.; Baron, A.; Roberts, S.; Junker, U.; Palacay-Ramona, M.; Manson, E.; Kay, A.; Wiedenmann, B.; Laurent, D.; Cebon, J. Influence of hepatic dysfunction on safety, tolerability, and pharmacokinetics (PK) of PTK787/ZK222584 in patients with unresectable hepatocellular carcinoma. J. Clin. Oncol. 2005, 23, 4134.
-
(2005)
J. Clin. Oncol
, vol.23
, pp. 4134
-
-
Koch, I.1
Baron, A.2
Roberts, S.3
Junker, U.4
Palacay-Ramona, M.5
Manson, E.6
Kay, A.7
Wiedenmann, B.8
Laurent, D.9
Cebon, J.10
-
205
-
-
78249288161
-
Phase 1-2 trial of PTK787/ZK222584 combined with intravenous doxorubicin for treatment of patients with advanced hepatocellular carcinoma
-
Yau, T.; Chan, P.; Pang, R.; Ng, K.; Fan, S. T.; Poon, R. T. Phase 1-2 trial of PTK787/ZK222584 combined with intravenous doxorubicin for treatment of patients with advanced hepatocellular carcinoma. Cancer 2010, 116, 5022-5029.
-
(2010)
Cancer
, vol.116
, pp. 5022-5029
-
-
Yau, T.1
Chan, P.2
Pang, R.3
Ng, K.4
Fan, S.T.5
Poon, R.T.6
-
206
-
-
0033916672
-
Activity of thalidomide in AIDS-related Kaposi's sarcoma
-
Little, R. F.; Wyvill, K. M.; Pluda, J. M.; Welles, L; Marshall, V; Figg, W. D.; Newcomb, F. M.; Tosato, G.; Feigal, E.; Steinberg, S. M.; Whitby, D.; Goedert, J. J.; Yarchoan, R. Activity of thalidomide in AIDS-related Kaposi's sarcoma. J. Clin. Oncol. 2000, 18, 2593-2602.
-
(2000)
J. Clin. Oncol
, vol.18
, pp. 2593-2602
-
-
Little, R.F.1
Wyvill, K.M.2
Pluda, J.M.3
Welles, L.4
Marshall, V.5
Figg, W.D.6
Newcomb, F.M.7
Tosato, G.8
Feigal, E.9
Steinberg, S.M.10
Whitby, D.11
Goedert, J.J.12
Yarchoan, R.13
-
207
-
-
85027956130
-
Activity of thalidomide and capecitabine in patients with advanced hepatocellular carcinoma
-
Ang, S. F.; Tan, S. H.; Toh, H. C.; Poon, D. Y.; Ong, S. Y.; Foo, K. F.; Choo, S. P. Activity of thalidomide and capecitabine in patients with advanced hepatocellular carcinoma. Am. J. Clin. Oncol. 2012, 35, 222-227.
-
(2012)
Am. J. Clin. Oncol
, vol.35
, pp. 222-227
-
-
Ang, S.F.1
Tan, S.H.2
Toh, H.C.3
Poon, D.Y.4
Ong, S.Y.5
Foo, K.F.6
Choo, S.P.7
-
208
-
-
79951789375
-
Thalidomide, lenalidomide and bortezomib in the management of newly diagnosed multiple myeloma
-
Laubach, J. P.; Schlossman, R. L.; Mitsiades, C. S.; Anderson, K. C.; Richardson, P. G. Thalidomide, lenalidomide and bortezomib in the management of newly diagnosed multiple myeloma. Expert Rev. Hematol. 2011, 4, 51-60.
-
(2011)
Expert Rev. Hematol
, vol.4
, pp. 51-60
-
-
Laubach, J.P.1
Schlossman, R.L.2
Mitsiades, C.S.3
Anderson, K.C.4
Richardson, P.G.5
-
209
-
-
77958030144
-
Inhibitory effect of thalidomide on growth of human hepatoma cell line SMMC-7721 cells
-
Sun, P.; Zhang, L. M.; Sun, D. J.; Dong, L. L. Inhibitory effect of thalidomide on growth of human hepatoma cell line SMMC-7721 cells. Zhonghua Zhong Liu Za Zhi 2009, 31, 582-586.
-
(2009)
Zhonghua Zhong Liu Za Zhi
, vol.31
, pp. 582-586
-
-
Sun, P.1
Zhang, L.M.2
Sun, D.J.3
Dong, L.L.4
-
210
-
-
84984535366
-
Phase I and pharmacokinetic study of oral thalidomide in patients with advanced hepatocellular carcinoma
-
Shiah, H. S.; Chao, Y.; Chen, L. T.; Yao, T. J.; Huang, J. D.; Chang, J. Y.; Chen, P. J.; Chuang, T. R.; Chin, Y. H.; Whang-Peng, J.; Liu, T. W. Phase I and pharmacokinetic study of oral thalidomide in patients with advanced hepatocellular carcinoma. Cancer Chemother. Pharmacol. 2006, 58, 654-664.
-
(2006)
Cancer Chemother. Pharmacol
, vol.58
, pp. 654-664
-
-
Shiah, H.S.1
Chao, Y.2
Chen, L.T.3
Yao, T.J.4
Huang, J.D.5
Chang, J.Y.6
Chen, P.J.7
Chuang, T.R.8
Chin, Y.H.9
Whang-Peng, J.10
Liu, T.W.11
-
211
-
-
17644376932
-
Effect of thalidomide in hepatocellular carcinoma: Assessment with power Doppler US and analysis of circulating angiogenic factors
-
Hsu, C.; Chen, C. N.; Chen, L. T.; Wu, C. Y.; Hsieh, F. J.; Cheng, A. L. Effect of thalidomide in hepatocellular carcinoma: assessment with power Doppler US and analysis of circulating angiogenic factors. Radiology 2005, 235, 509-516.
-
(2005)
Radiology
, vol.235
, pp. 509-516
-
-
Hsu, C.1
Chen, C.N.2
Chen, L.T.3
Wu, C.Y.4
Hsieh, F.J.5
Cheng, A.L.6
-
212
-
-
10844248554
-
Phase II study of thalidomide in patients with unresectable hepatocellular carcinoma
-
Lin, A. Y.; Brophy, N.; Fisher, G. A.; So, S.; Biggs, C.; Yock, T. I.; Levitt, L. Phase II study of thalidomide in patients with unresectable hepatocellular carcinoma. Cancer 2004, 119-125.
-
(2004)
Cancer
, pp. 119-125
-
-
Lin, A.Y.1
Brophy, N.2
Fisher, G.A.3
So, S.4
Biggs, C.5
Yock, T.I.6
Levitt, L.7
-
213
-
-
13444303839
-
Thalidomide in the treatment of patients with hepatocellular carcinoma
-
Patt, Y. Z.; Hassan, M. M.; Lozano, R. D.; Nooka, A. K.; Schnirer, I. I.; Zeldis, J. B.; Abbruzzese, J. L.; Brown, T. D. Thalidomide in the treatment of patients with hepatocellular carcinoma. Cancer 2005, 103, 749-755.
-
(2005)
Cancer
, vol.103
, pp. 749-755
-
-
Patt, Y.Z.1
Hassan, M.M.2
Lozano, R.D.3
Nooka, A.K.4
Schnirer, I.I.5
Zeldis, J.B.6
Abbruzzese, J.L.7
Brown, T.D.8
-
214
-
-
37149051789
-
Efficacy and tolerability of low-dose thalidomide as first-line systemic treatment of patients with advanced hepatocellular carcinoma
-
Yau, T.; Chan, P.; Wong, H.; Ng, K. K.; Chok, S. H.; Cheung, T. T.; Lam, V.; Epstein, R. J.; Fan, S. T.; Poon, R. T. P. Efficacy and tolerability of low-dose thalidomide as first-line systemic treatment of patients with advanced hepatocellular carcinoma. Oncology 2007, 72, 67-71.
-
(2007)
Oncology
, vol.72
, pp. 67-71
-
-
Yau, T.1
Chan, P.2
Wong, H.3
Ng, K.K.4
Chok, S.H.5
Cheung, T.T.6
Lam, V.7
Epstein, R.J.8
Fan, S.T.9
Poon, R.T.P.10
-
215
-
-
53549121418
-
Thalidomide in advanced hepatocellular carcinoma as antiangiogenic treatment approach: A phase I/II trial
-
Pinter, M.; Winchlas, M.; Schmid, K.; Plank, C.; Müller, C.; Wrba, F.; Peck-Radosavljevic, M. Thalidomide in advanced hepatocellular carcinoma as antiangiogenic treatment approach: a phase I/II trial. Eur. J. Gastroenterol. Hepatol. 2008, 20, 1012-1019.
-
(2008)
Eur. J. Gastroenterol. Hepatol
, vol.20
, pp. 1012-1019
-
-
Pinter, M.1
Winchlas, M.2
Schmid, K.3
Plank, C.4
Müller, C.5
Wrba, F.6
Peck-Radosavljevic, M.7
-
216
-
-
47549118684
-
Adjuvant chemotherapy with tegafur/uracil administration after transcatheter arterial chemoembolization for advanced hepatocellular carcinoma
-
Ueda, H.; Tanaka, H.; Kida, Y.; Fukuchi, H.; Ichinose, M. Adjuvant chemotherapy with tegafur/uracil administration after transcatheter arterial chemoembolization for advanced hepatocellular carcinoma. Oncol. Reports 2008, 19, 1355-1361.
-
(2008)
Oncol. Reports
, vol.19
, pp. 1355-1361
-
-
Ueda, H.1
Tanaka, H.2
Kida, Y.3
Fukuchi, H.4
Ichinose, M.5
-
217
-
-
77957559384
-
Early alpha-fetoprotein response predicts treatment efficacy of antiangiogenic systemic efficacy of antiangiogenic systemic therapy in patients with advanced hepatocellular carcinoma
-
Shao, Y. Y.; Lin, Z. Z.; Hsu, C.; Shen, C. Y.; Hsu, C.C.; Cheng, A. L. Early alpha-fetoprotein response predicts treatment efficacy of antiangiogenic systemic efficacy of antiangiogenic systemic therapy in patients with advanced hepatocellular carcinoma. Cancer 2010, 116, 4590-4596.
-
(2010)
Cancer
, vol.116
, pp. 4590-4596
-
-
Shao, Y.Y.1
Lin, Z.Z.2
Hsu, C.3
Shen, C.Y.4
Hsu, C.C.5
Cheng, A.L.6
-
218
-
-
79953803472
-
A phase I/II trial of the oral antiangiogenic agent TSU-68 in patients with advanced hepatocellular carcinoma
-
Kanai, F.; Yoshida, H.; Tateishi, R.; Sato, S.; Kawabe, T.; Obi, S.; Kondo, Y.; Taniguchi, M.; Tagawa, K.; Ikeda, M.; Morizane, C.; Okusaka, T.; Arioka, H.; Shiina, S.; Omata, M. A phase I/II trial of the oral antiangiogenic agent TSU-68 in patients with advanced hepatocellular carcinoma. Cancer Chemother. Pharmacol. 2011, 67, 315-24.
-
(2011)
Cancer Chemother. Pharmacol
, vol.67
, pp. 315-324
-
-
Kanai, F.1
Yoshida, H.2
Tateishi, R.3
Sato, S.4
Kawabe, T.5
Obi, S.6
Kondo, Y.7
Taniguchi, M.8
Tagawa, K.9
Ikeda, M.10
Morizane, C.11
Okusaka, T.12
Arioka, H.13
Shiina, S.14
Omata, M.15
-
219
-
-
79955580873
-
HCC and angiogenesis: Possible targets and future directions
-
Zhu, A. X.; Duda, D. G.; Sahani, D. V.; Jain, R. K. HCC and angiogenesis: possible targets and future directions. Nature Revs. Clin. Oncol. 2011, 8, 292-302.
-
(2011)
Nature Revs. Clin. Oncol
, vol.8
, pp. 292-302
-
-
Zhu, A.X.1
Duda, D.G.2
Sahani, D.V.3
Jain, R.K.4
-
220
-
-
79956328903
-
Molecular mechanisms and clinical applications of angiogenesis
-
Carmeliet, P.; Jain, R. K. Molecular mechanisms and clinical applications of angiogenesis. Nature 2011, 473, 298-307.
-
(2011)
Nature
, vol.473
, pp. 298-307
-
-
Carmeliet, P.1
Jain, R.K.2
-
221
-
-
84855317068
-
Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer
-
Reuben, S. C.; Gopalan, A.; Petit, D. M.; Bishayee, A. Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer. Mol. Nutr. Food Res. 2012, 56, 14-29.
-
(2012)
Mol. Nutr. Food Res
, vol.56
, pp. 14-29
-
-
Reuben, S.C.1
Gopalan, A.2
Petit, D.M.3
Bishayee, A.4
|