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Volumn 4, Issue 3, 2010, Pages 537-547

Angiogenesis: Multiple masks in hepatocellular carcinoma and liver regeneration

Author keywords

Angiogenesis; Hepatocellular carcinoma; Liver regeneration; Metastasis

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOPOIETIN; BEVACIZUMAB; CYTOKINE; EVEROLIMUS; GROWTH FACTOR; PLACEBO; PLATELET DERIVED GROWTH FACTOR; RAPAMYCIN; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SORAFENIB; SUNITINIB; VASCULAR TARGETING AGENT; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

EID: 77958088824     PISSN: 19360533     EISSN: 19360541     Source Type: Journal    
DOI: 10.1007/s12072-010-9192-4     Document Type: Review
Times cited : (37)

References (110)
  • 3
    • 1942444404 scopus 로고    scopus 로고
    • Micrometastases of solitary hepatocellular carcinoma and appropriate resection margin
    • 15022021
    • M Shi CQ Zhang YQ Zhang XM Liang JQ Li 2004 Micrometastases of solitary hepatocellular carcinoma and appropriate resection margin World J Surg 28 4 376 381 15022021
    • (2004) World J Surg , vol.28 , Issue.4 , pp. 376-381
    • Shi, M.1    Zhang, C.Q.2    Zhang, Y.Q.3    Liang, X.M.4    Li, J.Q.5
  • 4
    • 43049095225 scopus 로고    scopus 로고
    • Anatomic versus limited nonanatomic resection for solitary hepatocellular carcinoma
    • 18436008
    • K Tanaka H Shimada C Matsumoto K Matsuo Y Nagano I Endo S Togo 2008 Anatomic versus limited nonanatomic resection for solitary hepatocellular carcinoma Surgery 143 5 607 615 18436008
    • (2008) Surgery , vol.143 , Issue.5 , pp. 607-615
    • Tanaka, K.1    Shimada, H.2    Matsumoto, C.3    Matsuo, K.4    Nagano, Y.5    Endo, I.6    Togo, S.7
  • 6
    • 0021685081 scopus 로고
    • Liver regeneration and tumor growth in the rat after partial hepatectomy
    • 6442381
    • H Ichihashi H Mabuchi M Suenaga T Kondo 1984 Liver regeneration and tumor growth in the rat after partial hepatectomy Jpn J Surg 14 6 510 514 6442381
    • (1984) Jpn J Surg , vol.14 , Issue.6 , pp. 510-514
    • Ichihashi, H.1    Mabuchi, H.2    Suenaga, M.3    Kondo, T.4
  • 7
    • 0026651807 scopus 로고
    • Promotion of hepatic metastases by liver resection in the rat
    • 1616850
    • J Mizutani T Hiraoka R Yamashita Y Miyauchi 1992 Promotion of hepatic metastases by liver resection in the rat Br J Cancer 65 6 794 797 1616850
    • (1992) Br J Cancer , vol.65 , Issue.6 , pp. 794-797
    • Mizutani, J.1    Hiraoka, T.2    Yamashita, R.3    Miyauchi, Y.4
  • 8
    • 0031928718 scopus 로고    scopus 로고
    • Partial hepatectomy accelerates local tumor growth: Potential roles of local cytokine activation
    • 9663252
    • A Picardo HM Karpoff B Ng J Lee MF Brennan Y Fong 1998 Partial hepatectomy accelerates local tumor growth: potential roles of local cytokine activation Surgery 124 1 57 64 9663252
    • (1998) Surgery , vol.124 , Issue.1 , pp. 57-64
    • Picardo, A.1    Karpoff, H.M.2    Ng, B.3    Lee, J.4    Brennan, M.F.5    Fong, Y.6
  • 9
    • 0033770282 scopus 로고    scopus 로고
    • Major hepatic resection may suppress the growth of tumours remaining in the residual liver
    • 10993659
    • H Yokoyama S Goto CL Chen TL Pan K Kawano S Kitano 2000 Major hepatic resection may suppress the growth of tumours remaining in the residual liver Br J Cancer 83 8 1096 1101 10993659
    • (2000) Br J Cancer , vol.83 , Issue.8 , pp. 1096-1101
    • Yokoyama, H.1    Goto, S.2    Chen, C.L.3    Pan, T.L.4    Kawano, K.5    Kitano, S.6
  • 10
    • 0346970677 scopus 로고    scopus 로고
    • Angiogenesis inhibitor TNP-470 can suppress hepatocellular carcinoma growth without retarding liver regeneration after partial hepatectomy
    • 14714227
    • S Kinoshita R Hirai T Yamano I Yuasa K Tsukuda N Shimizu 2004 Angiogenesis inhibitor TNP-470 can suppress hepatocellular carcinoma growth without retarding liver regeneration after partial hepatectomy Surg Today 34 1 40 46 14714227
    • (2004) Surg Today , vol.34 , Issue.1 , pp. 40-46
    • Kinoshita, S.1    Hirai, R.2    Yamano, T.3    Yuasa, I.4    Tsukuda, K.5    Shimizu, N.6
  • 12
    • 42449089769 scopus 로고    scopus 로고
    • Liver regeneration and tumor stimulation: A review of cytokine and angiogenic factors
    • 18181006
    • C Christophi N Harun T Fifis 2008 Liver regeneration and tumor stimulation: a review of cytokine and angiogenic factors J Gastrointest Surg 12 5 966 980 18181006
    • (2008) J Gastrointest Surg , vol.12 , Issue.5 , pp. 966-980
    • Christophi, C.1    Harun, N.2    Fifis, T.3
  • 13
    • 33748940402 scopus 로고    scopus 로고
    • Role of angiogenesis in human tumor dormancy: Animal models of the angiogenic switch
    • 16931911
    • GN Naumov LA Akslen J Folkman 2006 Role of angiogenesis in human tumor dormancy: animal models of the angiogenic switch Cell Cycle 5 16 1779 1787 16931911
    • (2006) Cell Cycle , vol.5 , Issue.16 , pp. 1779-1787
    • Naumov, G.N.1    Akslen, L.A.2    Folkman, J.3
  • 14
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • 17957189
    • JA Aguirre-Ghiso 2007 Models, mechanisms and clinical evidence for cancer dormancy Nat Rev Cancer 7 11 834 846 17957189
    • (2007) Nat Rev Cancer , vol.7 , Issue.11 , pp. 834-846
    • Aguirre-Ghiso, J.A.1
  • 15
    • 33748923637 scopus 로고    scopus 로고
    • Dormant tumors awaken by a short-term angiogenic burst: The spike hypothesis
    • Indraccolo S, Favaro E, Amadori A. Dormant tumors awaken by a short-term angiogenic burst: the spike hypothesis. Cell Cycle 2006;5(16):1751-1755
    • (2006) Cell Cycle , vol.5 , Issue.16 , pp. 1751-1755
    • Indraccolo, S.1    Favaro, E.2    Amadori, A.3
  • 19
  • 20
    • 5044232017 scopus 로고    scopus 로고
    • Liver regeneration: From myth to mechanism
    • 15459664
    • R Taub 2004 Liver regeneration: from myth to mechanism Nat Rev Mol Cell Biol 5 10 836 847 15459664
    • (2004) Nat Rev Mol Cell Biol , vol.5 , Issue.10 , pp. 836-847
    • Taub, R.1
  • 21
    • 0021858187 scopus 로고
    • The liver sieve: Considerations concerning the structure and function of endothelial fenestrae, the sinusoidal wall and the space of Disse
    • 3926620
    • E Wisse RB De Zanger K Charels P Van Der Smissen RS McCuskey 1985 The liver sieve: considerations concerning the structure and function of endothelial fenestrae, the sinusoidal wall and the space of Disse Hepatology 5 4 683 692 3926620
    • (1985) Hepatology , vol.5 , Issue.4 , pp. 683-692
    • Wisse, E.1    De Zanger, R.B.2    Charels, K.3    Van Der Smissen, P.4    McCuskey, R.S.5
  • 22
    • 33947414087 scopus 로고    scopus 로고
    • Sinusoidal remodeling and angiogenesis: A new function for the liver-specific pericyte?
    • 17326208
    • JS Lee D Semela J Iredale VH Shah 2007 Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte? Hepatology 45 3 817 825 17326208
    • (2007) Hepatology , vol.45 , Issue.3 , pp. 817-825
    • Lee, J.S.1    Semela, D.2    Iredale, J.3    Shah, V.H.4
  • 23
    • 48549088729 scopus 로고    scopus 로고
    • Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function
    • 18570897
    • D Semela A Das D Langer N Kang E Leof V Shah 2008 Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function Gastroenterology 135 2 671 679 18570897
    • (2008) Gastroenterology , vol.135 , Issue.2 , pp. 671-679
    • Semela, D.1    Das, A.2    Langer, D.3    Kang, N.4    Leof, E.5    Shah, V.6
  • 24
    • 0035144232 scopus 로고    scopus 로고
    • Sinusoidal ultrastructure evaluated during the revascularization of regenerating rat liver
    • 11172338
    • KE Wack MA Ross V Zegarra LR Sysko SC Watkins DB Stolz 2001 Sinusoidal ultrastructure evaluated during the revascularization of regenerating rat liver Hepatology 33 2 363 378 11172338
    • (2001) Hepatology , vol.33 , Issue.2 , pp. 363-378
    • Wack, K.E.1    Ross, M.A.2    Zegarra, V.3    Sysko, L.R.4    Watkins, S.C.5    Stolz, D.B.6
  • 25
    • 0035190838 scopus 로고    scopus 로고
    • Spatiotemporal expression of angiogenesis growth factor receptors during the revascularization of regenerating rat liver
    • 11732003
    • MA Ross CM Sander TB Kleeb SC Watkins DB Stolz 2001 Spatiotemporal expression of angiogenesis growth factor receptors during the revascularization of regenerating rat liver Hepatology 34 6 1135 1148 11732003
    • (2001) Hepatology , vol.34 , Issue.6 , pp. 1135-1148
    • Ross, M.A.1    Sander, C.M.2    Kleeb, T.B.3    Watkins, S.C.4    Stolz, D.B.5
  • 26
    • 26044436859 scopus 로고    scopus 로고
    • Expression of hypoxia inducible factor-1alpha during liver regeneration induced by partial hepatectomy in rats
    • 16162160
    • H Maeno T Ono DK Dhar T Sato A Yamanoi N Nagasue 2005 Expression of hypoxia inducible factor-1alpha during liver regeneration induced by partial hepatectomy in rats Liver Int 25 5 1002 1009 16162160
    • (2005) Liver Int , vol.25 , Issue.5 , pp. 1002-1009
    • Maeno, H.1    Ono, T.2    Dhar, D.K.3    Sato, T.4    Yamanoi, A.5    Nagasue, N.6
  • 27
    • 1642450652 scopus 로고    scopus 로고
    • Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice
    • 14739103
    • CA Redaelli D Semela FE Carrick M Ledermann D Candinas B Sauter JF Dufour 2004 Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice J Hepatol 40 2 305 312 14739103
    • (2004) J Hepatol , vol.40 , Issue.2 , pp. 305-312
    • Redaelli, C.A.1    Semela, D.2    Carrick, F.E.3    Ledermann, M.4    Candinas, D.5    Sauter, B.6    Dufour, J.F.7
  • 28
    • 33748918542 scopus 로고    scopus 로고
    • Disruption of the Arnt gene in endothelial cells causes hepatic vascular defects and partial embryonic lethality in mice
    • 16941684
    • SH Yim Y Shah S Tomita HD Morris O Gavrilova G Lambert JM Ward FJ Gonzalez 2006 Disruption of the Arnt gene in endothelial cells causes hepatic vascular defects and partial embryonic lethality in mice Hepatology 44 3 550 560 16941684
    • (2006) Hepatology , vol.44 , Issue.3 , pp. 550-560
    • Yim, S.H.1    Shah, Y.2    Tomita, S.3    Morris, H.D.4    Gavrilova, O.5    Lambert, G.6    Ward, J.M.7    Gonzalez, F.J.8
  • 29
    • 0035189114 scopus 로고    scopus 로고
    • Expression and role of vascular endothelial growth factor in liver regeneration after partial hepatectomy in rats
    • 11118484
    • E Taniguchi S Sakisaka K Matsuo K Tanikawa M Sata 2001 Expression and role of vascular endothelial growth factor in liver regeneration after partial hepatectomy in rats J Histochem Cytochem 49 1 121 130 11118484
    • (2001) J Histochem Cytochem , vol.49 , Issue.1 , pp. 121-130
    • Taniguchi, E.1    Sakisaka, S.2    Matsuo, K.3    Tanikawa, K.4    Sata, M.5
  • 30
    • 0035013447 scopus 로고    scopus 로고
    • Vascular endothelial growth factor secreted by replicating hepatocytes induces sinusoidal endothelial cell proliferation during regeneration after partial hepatectomy in rats
    • 11434614
    • H Shimizu M Miyazaki Y Wakabayashi N Mitsuhashi A Kato H Ito K Nakagawa H Yoshidome M Kataoka N Nakajima 2001 Vascular endothelial growth factor secreted by replicating hepatocytes induces sinusoidal endothelial cell proliferation during regeneration after partial hepatectomy in rats J Hepatol 34 5 683 689 11434614
    • (2001) J Hepatol , vol.34 , Issue.5 , pp. 683-689
    • Shimizu, H.1    Miyazaki, M.2    Wakabayashi, Y.3    Mitsuhashi, N.4    Kato, A.5    Ito, H.6    Nakagawa, K.7    Yoshidome, H.8    Kataoka, M.9    Nakajima, N.10
  • 31
    • 0348013133 scopus 로고    scopus 로고
    • Vascular endothelial growth factor increases fenestral permeability in hepatic sinusoidal endothelial cells
    • 14986821
    • H Yokomori M Oda K Yoshimura T Nagai M Ogi M Nomura H Ishii 2003 Vascular endothelial growth factor increases fenestral permeability in hepatic sinusoidal endothelial cells Liver Int 23 6 467 475 14986821
    • (2003) Liver Int , vol.23 , Issue.6 , pp. 467-475
    • Yokomori, H.1    Oda, M.2    Yoshimura, K.3    Nagai, T.4    Ogi, M.5    Nomura, M.6    Ishii, H.7
  • 32
    • 0035024760 scopus 로고    scopus 로고
    • Sinusoidal endothelial cell proliferation and expression of angiopoietin/Tie family in regenerating rat liver
    • 11434615
    • T Sato ON El-Assal T Ono A Yamanoi DK Dhar N Nagasue 2001 Sinusoidal endothelial cell proliferation and expression of angiopoietin/Tie family in regenerating rat liver J Hepatol 34 5 690 698 11434615
    • (2001) J Hepatol , vol.34 , Issue.5 , pp. 690-698
    • Sato, T.1    El-Assal, O.N.2    Ono, T.3    Yamanoi, A.4    Dhar, D.K.5    Nagasue, N.6
  • 33
    • 0033980284 scopus 로고    scopus 로고
    • Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells
    • 10613739
    • V Ankoma-Sey Y Wang Z Dai 2000 Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells Hepatology 31 1 141 148 10613739
    • (2000) Hepatology , vol.31 , Issue.1 , pp. 141-148
    • Ankoma-Sey, V.1    Wang, Y.2    Dai, Z.3
  • 35
    • 0036941610 scopus 로고    scopus 로고
    • The interaction of Neuropilin-1 and Neuropilin-2 with tyrosine-kinase receptors for VEGF
    • 12613545
    • G Neufeld O Kessler Y Herzog 2002 The interaction of Neuropilin-1 and Neuropilin-2 with tyrosine-kinase receptors for VEGF Adv Exp Med Biol 515 81 90 12613545
    • (2002) Adv Exp Med Biol , vol.515 , pp. 81-90
    • Neufeld, G.1    Kessler, O.2    Herzog, Y.3
  • 36
  • 37
    • 0026446859 scopus 로고
    • Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells
    • 1447317
    • EN Unemori N Ferrara EA Bauer EP Amento 1992 Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells J Cell Physiol 153 3 557 562 1447317
    • (1992) J Cell Physiol , vol.153 , Issue.3 , pp. 557-562
    • Unemori, E.N.1    Ferrara, N.2    Bauer, E.A.3    Amento, E.P.4
  • 38
    • 0032473560 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: Conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation
    • 9495249
    • S Zucker H Mirza CE Conner AF Lorenz MH Drews WF Bahou J Jesty 1998 Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation Int J Cancer 75 5 780 786 9495249
    • (1998) Int J Cancer , vol.75 , Issue.5 , pp. 780-786
    • Zucker, S.1    Mirza, H.2    Conner, C.E.3    Lorenz, A.F.4    Drews, M.H.5    Bahou, W.F.6    Jesty, J.7
  • 39
    • 0026321129 scopus 로고
    • Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells
    • 1755866
    • MS Pepper N Ferrara L Orci R Montesano 1991 Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells Biochem Biophys Res Commun 181 2 902 906 1755866
    • (1991) Biochem Biophys Res Commun , vol.181 , Issue.2 , pp. 902-906
    • Pepper, M.S.1    Ferrara, N.2    Orci, L.3    Montesano, R.4
  • 41
    • 0028867704 scopus 로고
    • The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells
    • 8846781
    • MC Puri J Rossant K Alitalo A Bernstein J Partanen 1995 The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells EMBO J 14 23 5884 5891 8846781
    • (1995) EMBO J , vol.14 , Issue.23 , pp. 5884-5891
    • Puri, M.C.1    Rossant, J.2    Alitalo, K.3    Bernstein, A.4    Partanen, J.5
  • 42
    • 34848864570 scopus 로고    scopus 로고
    • Liver regeneration
    • 17559071
    • GK Michalopoulos 2007 Liver regeneration J Cell Physiol 213 2 286 300 17559071
    • (2007) J Cell Physiol , vol.213 , Issue.2 , pp. 286-300
    • Michalopoulos, G.K.1
  • 43
    • 2442719965 scopus 로고    scopus 로고
    • The role of hepatic stellate cells in liver regeneration
    • 15158345
    • C Balabaud P Bioulac-Sage A Desmouliere 2004 The role of hepatic stellate cells in liver regeneration J Hepatol 40 6 1023 1026 15158345
    • (2004) J Hepatol , vol.40 , Issue.6 , pp. 1023-1026
    • Balabaud, C.1    Bioulac-Sage, P.2    Desmouliere, A.3
  • 44
    • 34848914316 scopus 로고    scopus 로고
    • Morphologic features in the regenerating liver-a comparative intravital, lightmicroscopical and ultrastructural analysis with focus on hepatic stellate cells
    • 17674035
    • T Budny D Palmes U Stratmann E Minin H Herbst HU Spiegel 2007 Morphologic features in the regenerating liver-a comparative intravital, lightmicroscopical and ultrastructural analysis with focus on hepatic stellate cells Virchows Arch 451 4 781 791 17674035
    • (2007) Virchows Arch , vol.451 , Issue.4 , pp. 781-791
    • Budny, T.1    Palmes, D.2    Stratmann, U.3    Minin, E.4    Herbst, H.5    Spiegel, H.U.6
  • 45
    • 2442653767 scopus 로고    scopus 로고
    • Role of hepatic stellate cell/hepatocyte interaction and activation of hepatic stellate cells in the early phase of liver regeneration in the rat
    • 15158330
    • A Mabuchi I Mullaney PW Sheard PA Hessian BL Mallard MN Tawadrous A Zimmermann H Senoo AM Wheatley 2004 Role of hepatic stellate cell/hepatocyte interaction and activation of hepatic stellate cells in the early phase of liver regeneration in the rat J Hepatol 40 6 910 916 15158330
    • (2004) J Hepatol , vol.40 , Issue.6 , pp. 910-916
    • Mabuchi, A.1    Mullaney, I.2    Sheard, P.W.3    Hessian, P.A.4    Mallard, B.L.5    Tawadrous, M.N.6    Zimmermann, A.7    Senoo, H.8    Wheatley, A.M.9
  • 46
    • 0033588842 scopus 로고    scopus 로고
    • New model of tumor angiogenesis: Dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
    • 10498889
    • J Holash SJ Wiegand GD Yancopoulos 1999 New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF Oncogene 18 38 5356 5362 10498889
    • (1999) Oncogene , vol.18 , Issue.38 , pp. 5356-5362
    • Holash, J.1    Wiegand, S.J.2    Yancopoulos, G.D.3
  • 48
    • 0030851764 scopus 로고    scopus 로고
    • Signaling vascular morphogenesis and maintenance
    • 9229772
    • D Hanahan 1997 Signaling vascular morphogenesis and maintenance Science 277 5322 48 50 9229772
    • (1997) Science , vol.277 , Issue.5322 , pp. 48-50
    • Hanahan, D.1
  • 52
    • 33947732977 scopus 로고    scopus 로고
    • Angiogenesis: An organizing principle for drug discovery?
    • DOI 10.1038/nrd2115, PII NRD2115
    • J Folkman 2007 Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov 6 4 273 286 17396134 (Pubitemid 46505878)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.4 , pp. 273-286
    • Folkman, J.1
  • 53
    • 28844480321 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma
    • 16250051
    • J Bruix M Sherman 2005 Management of hepatocellular carcinoma Hepatology 42 5 1208 1236 16250051
    • (2005) Hepatology , vol.42 , Issue.5 , pp. 1208-1236
    • Bruix, J.1    Sherman, M.2
  • 54
    • 0034810089 scopus 로고    scopus 로고
    • Cytokine receptors and signaling in hepatic stellate cells
    • 11586468
    • M Pinzani F Marra 2001 Cytokine receptors and signaling in hepatic stellate cells Semin Liver Dis 21 3 397 416 11586468
    • (2001) Semin Liver Dis , vol.21 , Issue.3 , pp. 397-416
    • Pinzani, M.1    Marra, F.2
  • 55
    • 0026027904 scopus 로고
    • Early stages of multistep hepatocarcinogenesis: Adenomatous hyperplasia and early hepatocellular carcinoma
    • 1848205
    • M Sakamoto S Hirohashi Y Shimosato 1991 Early stages of multistep hepatocarcinogenesis: adenomatous hyperplasia and early hepatocellular carcinoma Hum Pathol 22 2 172 178 1848205
    • (1991) Hum Pathol , vol.22 , Issue.2 , pp. 172-178
    • Sakamoto, M.1    Hirohashi, S.2    Shimosato, Y.3
  • 56
    • 0027985208 scopus 로고
    • Hitherto unrecognized arterioles within hepatocellular carcinoma
    • 7823255
    • H Himeno H Enzan T Saibara S Onishi Y Yamamoto 1994 Hitherto unrecognized arterioles within hepatocellular carcinoma J Pathol 174 3 217 222 7823255
    • (1994) J Pathol , vol.174 , Issue.3 , pp. 217-222
    • Himeno, H.1    Enzan, H.2    Saibara, T.3    Onishi, S.4    Yamamoto, Y.5
  • 57
    • 0028020879 scopus 로고
    • Sinusoidal capillarization in small hepatocellular carcinoma
    • 7530563
    • M Kin T Torimura T Ueno S Inuzuka K Tanikawa 1994 Sinusoidal capillarization in small hepatocellular carcinoma Pathol Int 44 10-11 771 778 7530563
    • (1994) Pathol Int , vol.44 , Issue.1011 , pp. 771-778
    • Kin, M.1    Torimura, T.2    Ueno, T.3    Inuzuka, S.4    Tanikawa, K.5
  • 58
    • 0004623809 scopus 로고    scopus 로고
    • Increased expression of vascular endothelial growth factor and angiogenesis in the early stage of multistep hepatocarcinogenesis
    • 10888784
    • YN Park YB Kim KM Yang C Park 2000 Increased expression of vascular endothelial growth factor and angiogenesis in the early stage of multistep hepatocarcinogenesis Arch Pathol Lab Med 124 7 1061 1065 10888784
    • (2000) Arch Pathol Lab Med , vol.124 , Issue.7 , pp. 1061-1065
    • Park, Y.N.1    Kim, Y.B.2    Yang, K.M.3    Park, C.4
  • 59
    • 0032746097 scopus 로고    scopus 로고
    • Correlation between the blood supply and grade of malignancy of hepatocellular nodules associated with liver cirrhosis: Evaluation by CT during intraarterial injection of contrast medium
    • 10587130
    • M Hayashi O Matsui K Ueda Y Kawamori M Kadoya J Yoshikawa T Gabata T Takashima A Nonomura Y Nakanuma 1999 Correlation between the blood supply and grade of malignancy of hepatocellular nodules associated with liver cirrhosis: evaluation by CT during intraarterial injection of contrast medium AJR Am J Roentgenol 172 4 969 976 10587130
    • (1999) AJR Am J Roentgenol , vol.172 , Issue.4 , pp. 969-976
    • Hayashi, M.1    Matsui, O.2    Ueda, K.3    Kawamori, Y.4    Kadoya, M.5    Yoshikawa, J.6    Gabata, T.7    Takashima, T.8    Nonomura, A.9    Nakanuma, Y.10
  • 60
    • 0033367514 scopus 로고    scopus 로고
    • Phenotypical and morphological alterations to rat sinusoidal endothelial cells in arterialized livers after portal branch ligation
    • 10678569
    • M Yamasaki K Ikeda K Nakatani T Yamamoto Y Kawai K Hirohashi H Kinoshita K Kaneda 1999 Phenotypical and morphological alterations to rat sinusoidal endothelial cells in arterialized livers after portal branch ligation Arch Histol Cytol 62 5 401 411 10678569
    • (1999) Arch Histol Cytol , vol.62 , Issue.5 , pp. 401-411
    • Yamasaki, M.1    Ikeda, K.2    Nakatani, K.3    Yamamoto, T.4    Kawai, Y.5    Hirohashi, K.6    Kinoshita, H.7    Kaneda, K.8
  • 61
    • 0036234428 scopus 로고    scopus 로고
    • Hypoxia-induced VEGF and collagen i expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis
    • 11981751
    • C Corpechot V Barbu D Wendum N Kinnman C Rey R Poupon C Housset O Rosmorduc 2002 Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis Hepatology 35 5 1010 1021 11981751
    • (2002) Hepatology , vol.35 , Issue.5 , pp. 1010-1021
    • Corpechot, C.1    Barbu, V.2    Wendum, D.3    Kinnman, N.4    Rey, C.5    Poupon, R.6    Housset, C.7    Rosmorduc, O.8
  • 63
    • 0036432994 scopus 로고    scopus 로고
    • Hypoxia-induced angiogenesis in human hepatocellular carcinoma
    • 12436347
    • KR Kim HE Moon KW Kim 2002 Hypoxia-induced angiogenesis in human hepatocellular carcinoma J Mol Med 80 11 703 714 12436347
    • (2002) J Mol Med , vol.80 , Issue.11 , pp. 703-714
    • Kim, K.R.1    Moon, H.E.2    Kim, K.W.3
  • 64
    • 1442290121 scopus 로고    scopus 로고
    • Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha
    • 14688211
    • EJ Moon CH Jeong JW Jeong KR Kim DY Yu S Murakami CW Kim KW Kim 2004 Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha FASEB J 18 2 382 384 14688211
    • (2004) FASEB J , vol.18 , Issue.2 , pp. 382-384
    • Moon, E.J.1    Jeong, C.H.2    Jeong, J.W.3    Kim, K.R.4    Yu, D.Y.5    Murakami, S.6    Kim, C.W.7    Kim, K.W.8
  • 65
    • 0035164117 scopus 로고    scopus 로고
    • Dual mechanism of vascular endothelial growth factor upregulation by hypoxia in human hepatocellular carcinoma
    • Z von Marschall T Cramer M Hocker G Finkenzeller B Wiedenmann S Rosewicz 2001 Dual mechanism of vascular endothelial growth factor upregulation by hypoxia in human hepatocellular carcinoma Gut 48 1 87 96
    • (2001) Gut , vol.48 , Issue.1 , pp. 87-96
    • Von Marschall, Z.1    Cramer, T.2    Hocker, M.3    Finkenzeller, G.4    Wiedenmann, B.5    Rosewicz, S.6
  • 66
  • 68
    • 0034219429 scopus 로고    scopus 로고
    • Expression and localization of vascular endothelial growth factor receptors in human hepatocellular carcinoma and non-HCC tissues
    • 10854533
    • R Yamaguchi H Yano Y Nakashima S Ogasawara K Higaki J Akiba DJ Hicklin M Kojiro 2000 Expression and localization of vascular endothelial growth factor receptors in human hepatocellular carcinoma and non-HCC tissues Oncol Rep 7 4 725 729 10854533
    • (2000) Oncol Rep , vol.7 , Issue.4 , pp. 725-729
    • Yamaguchi, R.1    Yano, H.2    Nakashima, Y.3    Ogasawara, S.4    Higaki, K.5    Akiba, J.6    Hicklin, D.J.7    Kojiro, M.8
  • 70
    • 34548671423 scopus 로고    scopus 로고
    • Vascular endothelial growth factor, its receptor Flk-1, and hypoxia inducible factor-1alpha are involved in malignant transformation in dysplastic nodules of the liver
    • 17640715
    • K Nakamura Y Zen Y Sato K Kozaka O Matsui K Harada Y Nakanuma 2007 Vascular endothelial growth factor, its receptor Flk-1, and hypoxia inducible factor-1alpha are involved in malignant transformation in dysplastic nodules of the liver Hum Pathol 38 10 1532 1546 17640715
    • (2007) Hum Pathol , vol.38 , Issue.10 , pp. 1532-1546
    • Nakamura, K.1    Zen, Y.2    Sato, Y.3    Kozaka, K.4    Matsui, O.5    Harada, K.6    Nakanuma, Y.7
  • 71
    • 0035190559 scopus 로고    scopus 로고
    • Microvessel density, vascular endothelial growth factor and its receptors Flt-1 and Flk-1/KDR in hepatocellular carcinoma
    • 11764072
    • IO Ng RT Poon JM Lee ST Fan M Ng WK Tso 2001 Microvessel density, vascular endothelial growth factor and its receptors Flt-1 and Flk-1/KDR in hepatocellular carcinoma Am J Clin Pathol 116 6 838 845 11764072
    • (2001) Am J Clin Pathol , vol.116 , Issue.6 , pp. 838-845
    • Ng, I.O.1    Poon, R.T.2    Lee, J.M.3    Fan, S.T.4    Ng, M.5    Tso, W.K.6
  • 72
    • 0036254553 scopus 로고    scopus 로고
    • Requisite role of VEGF receptors in angiogenesis of hepatocellular carcinoma: A comparison with angiopoietin/Tie pathway
    • 12017318
    • DK Dhar H Naora A Yamanoi T Ono H Kohno H Otani N Nagasue 2002 Requisite role of VEGF receptors in angiogenesis of hepatocellular carcinoma: a comparison with angiopoietin/Tie pathway Anticancer Res 22 1A 379 386 12017318
    • (2002) Anticancer Res , vol.22 , Issue.1 A , pp. 379-386
    • Dhar, D.K.1    Naora, H.2    Yamanoi, A.3    Ono, T.4    Kohno, H.5    Otani, H.6    Nagasue, N.7
  • 73
    • 25144488259 scopus 로고    scopus 로고
    • Different cascades in the signaling pathway of two vascular endothelial growth factor (VEGF) receptors for the VEGF-mediated murine hepatocellular carcinoma development
    • 15809749
    • H Yoshiji R Noguchi S Kuriyama J Yoshii Y Ikenaka K Yanase T Namisaki M Kitade M Yamazaki M Uemura H Fukui 2005 Different cascades in the signaling pathway of two vascular endothelial growth factor (VEGF) receptors for the VEGF-mediated murine hepatocellular carcinoma development Oncol Rep 13 5 853 857 15809749
    • (2005) Oncol Rep , vol.13 , Issue.5 , pp. 853-857
    • Yoshiji, H.1    Noguchi, R.2    Kuriyama, S.3    Yoshii, J.4    Ikenaka, Y.5    Yanase, K.6    Namisaki, T.7    Kitade, M.8    Yamazaki, M.9    Uemura, M.10    Fukui, H.11
  • 76
    • 33748630200 scopus 로고    scopus 로고
    • Expression of angiopoietins, Tie2 and vascular endothelial growth factor in angiogenesis and progression of hepatocellular carcinoma
    • 16830384
    • ZL Zhang ZS Liu Q Sun 2006 Expression of angiopoietins, Tie2 and vascular endothelial growth factor in angiogenesis and progression of hepatocellular carcinoma World J Gastroenterol 12 26 4241 4245 16830384
    • (2006) World J Gastroenterol , vol.12 , Issue.26 , pp. 4241-4245
    • Zhang, Z.L.1    Liu, Z.S.2    Sun, Q.3
  • 77
    • 28144445732 scopus 로고    scopus 로고
    • Angiopoietin 2 displays a vascular endothelial growth factor dependent synergistic effect in hepatocellular carcinoma development in mice
    • 16033879
    • H Yoshiji S Kuriyama R Noguchi J Yoshii Y Ikenaka K Yanase T Namisaki M Kitade M Uemura T Masaki H Fukui 2005 Angiopoietin 2 displays a vascular endothelial growth factor dependent synergistic effect in hepatocellular carcinoma development in mice Gut 54 12 1768 1775 16033879
    • (2005) Gut , vol.54 , Issue.12 , pp. 1768-1775
    • Yoshiji, H.1    Kuriyama, S.2    Noguchi, R.3    Yoshii, J.4    Ikenaka, Y.5    Yanase, K.6    Namisaki, T.7    Kitade, M.8    Uemura, M.9    Masaki, T.10    Fukui, H.11
  • 78
    • 56149106773 scopus 로고    scopus 로고
    • The angiogenic makeup of human hepatocellular carcinoma does not favor vascular endothelial growth factor/angiopoietin-driven sprouting neovascularization
    • 18924243
    • W Zeng AS Gouw MC van den Heuvel PJ Zwiers PE Zondervan S Poppema N Zhang I Platteel KP de Jong G Molema 2008 The angiogenic makeup of human hepatocellular carcinoma does not favor vascular endothelial growth factor/angiopoietin-driven sprouting neovascularization Hepatology 48 5 1517 1527 18924243
    • (2008) Hepatology , vol.48 , Issue.5 , pp. 1517-1527
    • Zeng, W.1    Gouw, A.S.2    Van Den Heuvel, M.C.3    Zwiers, P.J.4    Zondervan, P.E.5    Poppema, S.6    Zhang, N.7    Platteel, I.8    De Jong, K.P.9    Molema, G.10
  • 79
    • 34047118033 scopus 로고    scopus 로고
    • Vascular remodeling and antitumoral effects of mTOR inhibition in a rat model of hepatocellular carcinoma
    • 17321636
    • D Semela AC Piguet M Kolev K Schmitter R Hlushchuk V Djonov C Stoupis JF Dufour 2007 Vascular remodeling and antitumoral effects of mTOR inhibition in a rat model of hepatocellular carcinoma J Hepatol 46 5 840 848 17321636
    • (2007) J Hepatol , vol.46 , Issue.5 , pp. 840-848
    • Semela, D.1    Piguet, A.C.2    Kolev, M.3    Schmitter, K.4    Hlushchuk, R.5    Djonov, V.6    Stoupis, C.7    Dufour, J.F.8
  • 80
    • 0033964164 scopus 로고    scopus 로고
    • Intussusceptive angiogenesis: Its role in embryonic vascular network formation
    • 10679480
    • V Djonov M Schmid SA Tschanz PH Burri 2000 Intussusceptive angiogenesis: its role in embryonic vascular network formation Circ Res 86 3 286 292 10679480
    • (2000) Circ Res , vol.86 , Issue.3 , pp. 286-292
    • Djonov, V.1    Schmid, M.2    Tschanz, S.A.3    Burri, P.H.4
  • 81
    • 66149137539 scopus 로고    scopus 로고
    • Chronic hypoxia attenuates VEGF signaling and angiogenic responses by downregulation of KDR in human endothelial cells
    • 19244479
    • B Olszewska-Pazdrak TW Hein P Olszewska DH Carney 2009 Chronic hypoxia attenuates VEGF signaling and angiogenic responses by downregulation of KDR in human endothelial cells Am J Physiol Cell Physiol 296 5 C1162 C1170 19244479
    • (2009) Am J Physiol Cell Physiol , vol.296 , Issue.5
    • Olszewska-Pazdrak, B.1    Hein, T.W.2    Olszewska, P.3    Carney, D.H.4
  • 82
    • 56849104158 scopus 로고    scopus 로고
    • Angiogenic characteristics in hepatocellular carcinomas: A comparison of HCCs in cirrhotic and non-cirrhotic livers and the influence of grading
    • (abstract)
    • J Weng AS Gouw MC Heuvel S Poppema KP Jong 2006 Angiogenic characteristics in hepatocellular carcinomas: a comparison of HCCs in cirrhotic and non-cirrhotic livers and the influence of grading Hepatology 44 Suppl 1 506A (abstract)
    • (2006) Hepatology , vol.44 , Issue.SUPPL. 1
    • Weng, J.1    Gouw, A.S.2    Heuvel, M.C.3    Poppema, S.4    Jong, K.P.5
  • 83
    • 33750621103 scopus 로고    scopus 로고
    • Significance of circulating endothelial progenitor cells in hepatocellular carcinoma
    • 17006919
    • JW Ho RW Pang C Lau CK Sun WC Yu ST Fan RT Poon 2006 Significance of circulating endothelial progenitor cells in hepatocellular carcinoma Hepatology 44 4 836 843 17006919
    • (2006) Hepatology , vol.44 , Issue.4 , pp. 836-843
    • Ho, J.W.1    Pang, R.W.2    Lau, C.3    Sun, C.K.4    Yu, W.C.5    Fan, S.T.6    Poon, R.T.7
  • 84
    • 34447114446 scopus 로고    scopus 로고
    • Identification and clinical significance of mobilized endothelial progenitor cells in tumor vasculogenesis of hepatocellular carcinoma
    • 17606712
    • D Yu X Sun Y Qiu J Zhou Y Wu L Zhuang J Chen Y Ding 2007 Identification and clinical significance of mobilized endothelial progenitor cells in tumor vasculogenesis of hepatocellular carcinoma Clin Cancer Res 13 13 3814 3824 17606712
    • (2007) Clin Cancer Res , vol.13 , Issue.13 , pp. 3814-3824
    • Yu, D.1    Sun, X.2    Qiu, Y.3    Zhou, J.4    Wu, Y.5    Zhuang, L.6    Chen, J.7    Ding, Y.8
  • 86
    • 75449104452 scopus 로고    scopus 로고
    • Expression and functional significance of Twist1 in hepatocellular carcinoma: Its role in vasculogenic mimicry
    • Sun T, Zhao N, Zhao XL, Gu Q, Zhang SW, Che N, Wang XH, Du J, Liu YX, Sun BC. Expression and functional significance of Twist1 in hepatocellular carcinoma: its role in vasculogenic mimicry. Hepatology 2010;51(2):545-556
    • (2010) Hepatology , vol.51 , Issue.2 , pp. 545-556
    • Sun, T.1    Zhao, N.2    Zhao, X.L.3    Gu, Q.4    Zhang, S.W.5    Che, N.6    Wang, X.H.7    Du, J.8    Liu, Y.X.9    Sun, B.C.10
  • 87
    • 33947590737 scopus 로고    scopus 로고
    • Vasculogenic mimicry is associated with high tumor grade, invasion and metastasis, and short survival in patients with hepatocellular carcinoma
    • 16969481
    • B Sun S Zhang D Zhang J Du H Guo X Zhao W Zhang X Hao 2006 Vasculogenic mimicry is associated with high tumor grade, invasion and metastasis, and short survival in patients with hepatocellular carcinoma Oncol Rep 16 4 693 698 16969481
    • (2006) Oncol Rep , vol.16 , Issue.4 , pp. 693-698
    • Sun, B.1    Zhang, S.2    Zhang, D.3    Du, J.4    Guo, H.5    Zhao, X.6    Zhang, W.7    Hao, X.8
  • 88
    • 37349055797 scopus 로고    scopus 로고
    • A pilot study of vasculogenic mimicry immunohistochemical expression in hepatocellular carcinoma
    • 18081435
    • G Guzman SJ Cotler AY Lin AJ Maniotis R Folberg 2007 A pilot study of vasculogenic mimicry immunohistochemical expression in hepatocellular carcinoma Arch Pathol Lab Med 131 12 1776 1781 18081435
    • (2007) Arch Pathol Lab Med , vol.131 , Issue.12 , pp. 1776-1781
    • Guzman, G.1    Cotler, S.J.2    Lin, A.Y.3    Maniotis, A.J.4    Folberg, R.5
  • 89
    • 36148937125 scopus 로고    scopus 로고
    • Tumour vascularization: Sprouting angiogenesis and beyond
    • 17717633
    • F Hillen AW Griffioen 2007 Tumour vascularization: sprouting angiogenesis and beyond Cancer Metastasis Rev 26 3,4 489 502 17717633
    • (2007) Cancer Metastasis Rev , vol.26 , Issue.3-4 , pp. 489-502
    • Hillen, F.1    Griffioen, A.W.2
  • 90
    • 0027992961 scopus 로고
    • Quantitative immunohistological analysis of the microvasculature in untreated human glioblastoma multiforme. Computer-assisted image analysis of whole-tumor sections
    • 7525899
    • P Wesseling JA van der Laak H de Leeuw DJ Ruiter PC Burger 1994 Quantitative immunohistological analysis of the microvasculature in untreated human glioblastoma multiforme. Computer-assisted image analysis of whole-tumor sections J Neurosurg 81 6 902 909 7525899
    • (1994) J Neurosurg , vol.81 , Issue.6 , pp. 902-909
    • Wesseling, P.1    Van Der Laak, J.A.2    De Leeuw, H.3    Ruiter, D.J.4    Burger, P.C.5
  • 93
    • 0030808102 scopus 로고    scopus 로고
    • Immunohistochemical studies on endothelial cell phenotype in hepatocellular carcinoma
    • 9252152
    • S Nakamura H Muro S Suzuki T Sakaguchi H Konno S Baba AS Syed 1997 Immunohistochemical studies on endothelial cell phenotype in hepatocellular carcinoma Hepatology 26 2 407 415 9252152
    • (1997) Hepatology , vol.26 , Issue.2 , pp. 407-415
    • Nakamura, S.1    Muro, H.2    Suzuki, S.3    Sakaguchi, T.4    Konno, H.5    Baba, S.6    Syed, A.S.7
  • 97
    • 0035890540 scopus 로고    scopus 로고
    • LYVE-1 is not restricted to the lymph vessels: Expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis
    • 11719431
    • C Mouta Carreira SM Nasser E di Tomaso TP Padera Y Boucher SI Tomarev RK Jain 2001 LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis Cancer Res 61 22 8079 8084 11719431
    • (2001) Cancer Res , vol.61 , Issue.22 , pp. 8079-8084
    • Mouta Carreira, C.1    Nasser, S.M.2    Di Tomaso, E.3    Padera, T.P.4    Boucher, Y.5    Tomarev, S.I.6    Jain, R.K.7
  • 100
    • 45849098736 scopus 로고    scopus 로고
    • Lymph circulation in the liver
    • O Ohtani Y Ohtani 2008 Lymph circulation in the liver Anat Rec (Hoboken) 291 6 643 652
    • (2008) Anat Rec (Hoboken) , vol.291 , Issue.6 , pp. 643-652
    • Ohtani, O.1    Ohtani, Y.2
  • 101
    • 34250372946 scopus 로고    scopus 로고
    • Hepatitis B × antigen up-regulates vascular endothelial growth factor receptor 3 in hepatocarcinogenesis
    • 17539024
    • Z Lian J Liu M Wu HY Wang P Arbuthnot M Kew MA Feitelson 2007 Hepatitis B × antigen up-regulates vascular endothelial growth factor receptor 3 in hepatocarcinogenesis Hepatology 45 6 1390 1399 17539024
    • (2007) Hepatology , vol.45 , Issue.6 , pp. 1390-1399
    • Lian, Z.1    Liu, J.2    Wu, M.3    Wang, H.Y.4    Arbuthnot, P.5    Kew, M.6    Feitelson, M.A.7
  • 103
    • 14544305077 scopus 로고    scopus 로고
    • Combination of antiangiogenic therapy with other anticancer therapies: Results, challenges, and open questions
    • 15718328
    • G Gasparini R Longo M Fanelli BA Teicher 2005 Combination of antiangiogenic therapy with other anticancer therapies: results, challenges, and open questions J Clin Oncol 23 6 1295 1311 15718328
    • (2005) J Clin Oncol , vol.23 , Issue.6 , pp. 1295-1311
    • Gasparini, G.1    Longo, R.2    Fanelli, M.3    Teicher, B.A.4
  • 104
    • 58149234169 scopus 로고    scopus 로고
    • Molecular therapy for the treatment of hepatocellular carcinoma
    • 19018262
    • TF Greten F Korangy MP Manns NP Malek 2009 Molecular therapy for the treatment of hepatocellular carcinoma Br J Cancer 100 1 19 23 19018262
    • (2009) Br J Cancer , vol.100 , Issue.1 , pp. 19-23
    • Greten, T.F.1    Korangy, F.2    Manns, M.P.3    Malek, N.P.4
  • 107
  • 108
    • 0037341637 scopus 로고    scopus 로고
    • Antivascular therapy of cancer: DMXAA
    • 12623359
    • BC Baguley 2003 Antivascular therapy of cancer: DMXAA Lancet Oncol 4 3 141 148 12623359
    • (2003) Lancet Oncol , vol.4 , Issue.3 , pp. 141-148
    • Baguley, B.C.1
  • 109
  • 110
    • 7244250405 scopus 로고    scopus 로고
    • Angiogenesis and hepatocellular carcinoma
    • 15519663
    • D Semela JF Dufour 2004 Angiogenesis and hepatocellular carcinoma J Hepatol 41 5 864 880 15519663
    • (2004) J Hepatol , vol.41 , Issue.5 , pp. 864-880
    • Semela, D.1    Dufour, J.F.2


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