Foretinib demonstrates anti-tumor activity and improves overall survival in preclinical models of hepatocellular carcinoma

Angiogenesis

Volumn 15, Issue 1, 2012, Pages 59-70

  Huynh, Hung ^a   Ong, Richard ^a   Soo, Khee Chee ^a  

^a DIVISION OF MEDICAL ONCOLOGY   (Singapore)

Author keywords

Angiogenesis; Foretinib; Growth inhibition; HCC

Indexed keywords

BEVACIZUMAB; BIM PROTEIN; BIOLOGICAL MARKER; CYCLIN B1; FORETINIB; GSK 1363089G; MYC PROTEIN; PROTEIN P27; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SORAFENIB; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2; ANILIDE; ANTINEOPLASTIC AGENT; QUINOLINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CELL CYCLE ARREST; CELL MIGRATION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG DOSE COMPARISON; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; MALE; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; WESTERN BLOTTING; ANIMAL; CELL CYCLE; CELL MOTION; DRUG EFFECT; DRUG SCREENING; LIVER TUMOR; MOUSE MUTANT; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; SURVIVAL; TIME; TUMOR CELL LINE; VASCULARIZATION;

ANILIDES; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, SCID; NEOVASCULARIZATION, PATHOLOGIC; QUINOLINES; SURVIVAL ANALYSIS; TIME FACTORS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84861535274     PISSN: 09696970     EISSN: 15737209     Source Type: Journal    
DOI: 10.1007/s10456-011-9243-z     Document Type: Article

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