Enhancement of hexokinase II inhibitor-induced apoptosis in hepatocellular carcinoma cells via augmenting ER stress and anti-angiogenesis by protein disulfide isomerase inhibition

Journal of Bioenergetics and Biomembranes

Volumn 44, Issue 1, 2012, Pages 101-115

  Yu, Su Jong ^a   Yoon, Jung Hwan ^a   Yang, Jong In ^b   Cho, Eun Ju ^a   Kwak, Min Sun ^a   Jang, Eun Sun ^a   Lee, Jeong Hoon ^a   Kim, Yoon Jun ^a   Lee, Hyo Suk ^a   Kim, Chung Yong ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University Hospital Healthcare System Gangnam Center   (South Korea)

Author keywords

Apoptosis; Hepatocellular carcinoma; Hexokinase II; Hypoxia; Protein disulfide isomerase

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTINEOPLASTIC AGENT; BACITRACIN; BROMOPYRUVIC ACID; HEXOKINASE II INHIBITOR; PROTEIN DISULFIDE ISOMERASE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CATALYST; CELL DEATH; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOBLOTTING; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; APOPTOSIS; BACITRACIN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM STRESS; HEXOKINASE; HUMANS; IMMUNOBLOTTING; INDOLES; MALE; MICE; MICROVESSELS; PROTEIN DISULFIDE-ISOMERASES; PYRUVATES; STATISTICS, NONPARAMETRIC;

MUS;

EID: 84862777172     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-012-9416-5     Document Type: Article

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